LOCUS       c00920_gnlPro..        14863 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMFJGOLO_920.
ACCESSION   c00920_gnlPro..
VERSION     c00920_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:00:45
            Original ID  :: gnl|Prokka|BMFJGOLO_920
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14863
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..96)
                     /locus_tag="ctg920_1"
                     /transl_table=11
                     /translation="MLIYKAVQSNIASKDKKKKWHPCLIKMGNVVD"
     protocluster    1..14863
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9897:14454]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9898..14454
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..14863
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14863
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             330..524
                     /locus_tag="ctg920_2"
                     /transl_table=11
                     /translation="MKKTELALLYMPYASADVARRHLNKCIRRNRELLEALEATGWAFW
                     IHWLTPLQVELIEKYLGEP"
     CDS             complement(815..2614)
                     /locus_tag="ctg920_3"
                     /transl_table=11
                     /translation="MDRFKELGIDTHGRTSGKMKTKCPWCHAQRTDKRDKSLSVNLDTK
                     LYLCHYCGAHGSAAIYAGKGRKLGDPLVKFPTATGSNSSCPPSEKPHGDPEQGALTQKQ
                     IEWCRDVRHIPPEVLVEAGVAFASISMPISGKEKGWEKRDCLCFNFFENGELVNTKFRD
                     SQKHFKLLQGARTIPYNIDAIRDTPECILVEGEFDALSYMAVGRTDVISVPNGANSQLD
                     WLDELSESHFEQKQVIYLSVDTDRKGRELCRELSRRLGVDRCRIVTYGEAYKDANELLV
                     AEGPDALLKALEDAPIPRLEGTFTAEDLREGLHQLFEEGYTSGVELGIPNLDEIMRLET
                     GRVLTVTGIPGHGKSDFVDEIVLRLCTRQDWRAGYFSPENTPIEYHHAKLAEKLLGHRF
                     RKDFSTEEEFARVVDYLSQRVWHILPDGDFTLGNVLSKARELVHRHGIRVFVIDPYNYI
                     NHQIPAGMTETGYIGSFMNSLARFARLNSCLVILVAHPRKMNKQYGTQKTEVPTMYDIN
                     GSANFFNMTDYGIVVDRQDEMGIVYIHVEKTRFRNFGTKGNAAFCYDVTNGRYSPCTPP
                     PEPGMQVQPWKGAKDLFSSEGWI"
     CDS             complement(2643..3947)
                     /locus_tag="ctg920_4"
                     /transl_table=11
                     /translation="MTTSNSANTKQSNNASQKRKPIHNGYFNHPTSSSSNIPMSILIRE
                     QGLEIYGLYWVMLEEAHAQLKCCVNIQTMGIIANIFHAQPEHLELLYHHYFRRPGKGYN
                     SHILYADFCEESAIRSYFPHPLLAYTDNELLRMIMQDGLKAYGLYWLVMEKLYQQPQHF
                     LAPQTASFIQNLYDVSDELMESVLYNYGLFYLDEKMNLHSKAIDDYREALDNMEDKKKR
                     NTKPHVNNSLKANGNAEDFNTREMKNTSNIQKNPSPIINKEINKKNSSSEESGKEKEEE
                     NGLKVTDLNAVTPDMRPNAWEENLQEAMNDTSWYEVVAIQSGIPRLMMEEKEWFFNYLR
                     EQIILRGNESSMNSLHEIKNYFANLTRQGSHVSSTTQVALKRFLKNRQEQQQCSPYETI
                     TNGIRTYDGHPIPAYAKPRPSAAHIWNPVTNEWTR"
     CDS             complement(4286..4681)
                     /locus_tag="ctg920_5"
                     /transl_table=11
                     /translation="MLTFQHKEICMKKTMKNDSCLTVSRRAAIIRQDAEENYGTLLTLG
                     ESMRRAYQVEELIDRMRWDNADFCLQRTDGTCLSITGTLTEYEHYFGRPYYENPSNRFL
                     PYYDVHCRKWLTCRVAGIVFGSSVKKN"
     CDS             complement(4958..5389)
                     /locus_tag="ctg920_6"
                     /transl_table=11
                     /translation="MPKWISVEKAVIKYHIEKEAILLWVEMGQFPMLYIDNVPNVDEEC
                     ILELFRRSKAGITAEYIDTLEQLCIDKTMVCEKYAHIIQLKEKEIQLQKEINTLINEIQ
                     AAMKRQNERIRDLKKAIGQNNNVIRSDSWIKRLRKRFQW"
     CDS             5656..5769
                     /locus_tag="ctg920_7"
                     /transl_table=11
                     /translation="MLIYDYLRGVSVVSSLGVKKLLIFKFERQYVIYSIKE"
     CDS             complement(6123..6530)
                     /locus_tag="ctg920_8"
                     /transl_table=11
                     /translation="MEITDLKQMTKEEVFNFIRQRLSFSKELQEQFRHVNKDDLAKEHR
                     RFEMSGNESKTGQCTIFNTAILNEFADLGIYDYTSYLFLDFHNGTPIVYLKYFSENENL
                     EYSFTGYTTTEIIFAILELTIFSGKPKRNRS"
     CDS             6724..7938
                     /locus_tag="ctg920_9"
                     /transl_table=11
                     /translation="MINREQYMEQIVPFIDKPFVKVITGIRRSGKSVVLRLIRDELLRR
                     GVREERIIYLNFESFQWIDLKEAKALYAYIRGQAGDAGKYYILLDEIQEVDGWEKVVNS
                     LLVDLDTDIYVTGSNSRMLSSELATYLTGRYVAFHVMTLSFREYLTFHDLQANDPTLNR
                     KEEFQKYLRMGGFPAIHTADYGYEAIYKIVYDIYSSVILRDTVQRHNIRNVELLERVVK
                     FVFDNIGNKLNAKNIADYFKSQQRKVDMNTIYNYLNALESAFIIQRIPRYDIKGKEILQ
                     TNEKYFVSDLSLIYSVMGYRDRLIAGMLENLVCLELKRRGYEVYVGKQDDKEVDFVAIR
                     REEKIYVQVTYQLASQATVEREFAPLLAINDHYPKYVVSMDSLWQDNVEGVRHRHIADF
                     LLDDA"
     CDS             complement(8019..8273)
                     /locus_tag="ctg920_10"
                     /transl_table=11
                     /translation="MKKGLHPESYRPVVFKDMSNGDMFLSRSTVATKETIEFEGETYPL
                     LKIEISNTSHPFYTGKSTLVDTAGRVDKFMSRYGDRKKK"
     CDS             8707..9711
                     /locus_tag="ctg920_11"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFEVVDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAVRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAQ"
     CDS             complement(9898..11058)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg920_12"
                     /sec_met_domain="OAD_beta (E-value: 1.1e-153, bitscore:
                     501.4, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATVGHVVMILVGLVFIYLAIAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKNERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFIIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDSTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(11060..11491)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.7; E-value:
                     2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg920_13"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.6e-22, bitscore:
                     67.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKPV
                     AKPVTVRPMPNAPAAPTQVVKPTAPSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVNKGDSVLEGNDLVIIE"
     CDS             complement(11516..12436)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg920_14"
                     /sec_met_domain="OAD_gamma (E-value: 9.4e-16, bitscore:
                     48.5, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLVLNEILIDNQSNFQD
                     DYGLHSAWIEIFNKSFGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGKKLLDQIVVPAGALGPNQSYARVSDGAAEW
                     EVKSGSGDKYVTPSTNNKTLDSNSKMEKFEEHDADGVGMSISAMSVVFCGLILLFIAFK
                     IVGKVAVNLSKRNAMKSKGIDKHEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRETPPRK"
     CDS             complement(12468..14021)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg920_15"
                     /sec_met_domain="CT_Btheta (E-value: 2.7e-290, bitscore:
                     953.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERLAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPT
                     KPYDMYEVIGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             complement(14050..14454)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg920_16"
                     /sec_met_domain="Glyoxalase_4 (E-value: 4.5e-24, bitscore:
                     75.1, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAEGKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             complement(14630..14863)
                     /locus_tag="ctg920_17"
                     /transl_table=11
                     /translation="RKTYALQYPGVLAVWKALEDAHQRGFRHMEFMDVGLPFRKHGYRD
                     FVLRFGGKQSSTRRWFRVNWSWLNKLLVKFYV"
ORIGIN
        1 atccactacg tttcccattt taatcaggca gggatgccat ttcttctttt tgtccttcga
       61 tgcgatattg gactgaaccg ctttgtaaat caacatactg atttcctcct ttttaagtga
      121 ataaataaga ttttattgag tcagtaaacg aacgttttct gtctctttta cagtagcaaa
      181 gataccccaa ccgacagggg aggaaacatg aaacggtatc tgccggtaag tgaaggcaaa
      241 cgcttgaata tctgtgtatt tgcttgcatt tctacgcaaa aaacagtatc tttacatgac
      301 gtaaataata aattaaaaga agaaaatcta tgaagaaaac ggaattggca ttactctata
      361 tgccgtatgc aagtgccgat gtggcaagaa gacatttaaa taaatgcatc cgccgaaacc
      421 gggagctgct ggaggctctc gaagctaccg gctgggcgtt ttggatacat tggctcacac
      481 cgttgcaggt ggagctgatt gagaagtatt tgggagagcc ttaatcccta tttttgatct
      541 cccaaaaacc attacgacga ccgtttttac gctctatgat gctcctttcg ctcaagttga
      601 cagtcatggt tttaacggtt ctttcagact ttcctatatg ctgggcaatt tctttttgtg
      661 ttgcattagg tttttcttga aggtatttca gtacggccat ttcttccaaa gtgcaatcca
      721 aagtgcaaaa attgcacttt ggattttctg tctctgtttg ttttgcactt tgagtagctt
      781 gcttttcaag ttattcttgt agcagcctta atccctaaat ccatccctct gacgagaata
      841 agtctttggc tcccttccac ggttgcacct gcatgcccgg ttcgggtggc ggcgtacaag
      901 gggaatatct tccgttggtc acatcgtagc agaacgctgc gtttcccttt gttccgaaat
      961 tacggaaacg ggttttctcg acatgtatat acacgatccc catttcatcc tgacggtcta
     1021 ccactattcc gtagtccgtc atgttgaaaa agttggccga gccgttgatg tcatacatgg
     1081 tgggaacttc cgttttctgc gtgccgtatt gcttgttcat ctttctcgga tgcgccacca
     1141 gaatgacgag gcaggagttg agccgggcaa aacgtgccag actattcatg aatgagccga
     1201 tataccccgt ctccgtcatg cctgccggga tctgatggtt gatgtaattg tacgggtcga
     1261 tgacaaacac acggatgccg tgacggtgca ccagttcgcg tgctttcgac aagacgttgc
     1321 ccagtgtgaa atccccgtcc ggaagaatgt gccagacgcg ttgcgaaaga taatccacta
     1381 cgcgggcgaa ttcctcctcc gtagagaaat ctttgcggaa acggtgtccc agcagttttt
     1441 ccgccagttt ggcatgatga tactcgattg gcgtgttctc cggactgaaa tatcccgctc
     1501 gccaatcttg gcgggtgcag agccggagca ctatctcatc tacaaagtcc gatttgccat
     1561 gtccgggaat accggtgacg gtgagcaccc gccccgtttc cagcctcatg atttcgtcca
     1621 gattcggtat tcccaattcc acgcccgaag tatacccctc ttcaaacagt tggtgcaacc
     1681 cctcccgtaa gtcttctgcc gtaaacgtac cttccaggcg ggggatgggc gcgtcctcca
     1741 gtgccttcag tagtgcgtcc gggccttccg ccacgagcag ttcgttggcg tccttgtatg
     1801 cttcgccgta ggtgacgata cggcagcggt ctacccccag ccgtcgggag agttcccggc
     1861 acagttcccg tcccttgcgg tcggtgtcca ccgacagata aatcacttgt ttctgctcga
     1921 aatgagattc cgacaattcg tccagccagt ccagttgact gttggcaccg ttcggcacgg
     1981 aaatgacatc cgtccggccg acagccatgt aggagagagc atcaaattcc ccttccacga
     2041 ggatgcactc cggcgtgtcg cggatagcgt cgatgttgta agggatggtg cgcgctcctt
     2101 gcagcaattt gaagtgcttt tgtgagtcgc ggaactttgt gttcaccaat tccccgtttt
     2161 cgaaaaagtt gaagcagaga cagtccctct tttcccagcc tttctccttt ccggatatag
     2221 gcatcgagat ggaggcgaaa gccacgccag cttccaccaa tacttccggc ggaatgtggc
     2281 ggacgtcacg acaccattca atttgcttct gtgtgagtgc cccttgctct gggtcgccgt
     2341 gcggcttttc agagggcgga caactggagt tgctacctgt tgccgttgga aatttgacca
     2401 acggatcacc cagctttctg ccttttccgg catatatggc tgccgaaccg tgtgcgccgc
     2461 agtagtggca caaatacagt ttggtatcga ggttgacact tagtgattta tcacgcttat
     2521 ccgtccgttg ggcatgacac cagggacatt ttgttttcat tttgccgctt gtgcgaccgt
     2581 gggtatcaat acccagttct ttgaatctat ccatatttag taaatgattg agagataata
     2641 tgctatcgtg tccattcgtt cgtcaccgga ttccagatat gtgccgccga aggtcgcggc
     2701 ttggcataag cggggatggg atgcccgtcg taggtacgta ttccgttggt gatggtttcg
     2761 tagggcgaac attgctgttg ctcttgccgg tttttgagaa acctcttcag tgccacctgc
     2821 gttgtggatg acacatggct tccctgccgg gtgagattgg cgaaatagtt ttttatttcg
     2881 tgcaggctgt tcatcgagct ttcattcccc cgtaagatga tttgctcccg taaatagttg
     2941 aagaaccatt ctttttcttc catcatcagc cgggggatgc ccgactgaat ggctacgact
     3001 tcataccagg atgtgtcgtt cattgcctcc tgtagatttt cttcccatgc gttggggcgc
     3061 atatcgggtg tcacagcgtt caagtccgtc accttcaaac cattttcttc ttctttttct
     3121 tttccgcttt cttcagaaga agaatttttt ttgtttattt ctttatttat aatgggggat
     3181 ggatttttct gtatatttga cgtatttttc atttcccgag tgttaaaatc ctctgcattt
     3241 ccgttggctt tcagagagtt attgacgtgc ggtttcgtgt tgcgcttttt tttatcttcc
     3301 atgttgtcaa gtgcttccct ataatcgtct attgctttag aatggaggtt cattttctca
     3361 tccagataaa agagtccgta attgtataat acactttcca tcagttcatc gctcacatca
     3421 taaaggttct ggatgaagga agcagtttgc ggtgccagaa aatgttgtgg ctgttgatag
     3481 agcttttcca tcacaagcca atatagtccg taggctttca gtccgtcttg cataatcatc
     3541 cgcagcagtt cgttgtcggt gtatgccagt agggggtgcg gaaaataact tctgatggca
     3601 gattcttcgc aaaagtcggc atagagtata tgcgagttgt atcctttgcc gggacgccgg
     3661 aaataatggt ggtagaggag ctcaagatgt tcgggttggg catggaatat attggcgatg
     3721 attcccattg tctggatatt gacgcagcat ttaagctgtg catgagcttc ttcgagcatc
     3781 acccagtata gtccgtatat ttccagtcct tgttcccgta tcaaaatact catgggtata
     3841 ttgctggaag aagaagtggg atgattgaag taaccgttat gaatcggttt tctcttttgt
     3901 gatgcgttgt tcgattgttt ggtatttgct gaattagatg ttgtcataat aaaatatatt
     3961 agtttctgtt ttaaattcta tttttctgaa aatacagata cgaagaatcc ggccacttct
     4021 taggaaagca gcaaatatcg tactcattct tcatgatgga atcggagtat tctcttcgtg
     4081 tatgtaatct gtaatatagg gaattttcgg agcaggggag atttaattcc gaagttctga
     4141 aaaagcaatg ctggaaaaac agataactgc ctctgtcaaa aaacaaggaa gcagcattga
     4201 catgattttt tctcttactt gcggttgcaa agtaactact ttatttcgta tatgtcctac
     4261 aactttcctt atttaatcca tgaaattaat tttttttcac agaagagccg aatacaatcc
     4321 ctgccactcg acacgtaagc cattttctac aatgcacgtc atagtatggg agaaacctgt
     4381 tggaggggtt ttcgtagtag gggcggccga aatagtgttc atattctgtc agtgtccctg
     4441 taatggaaag gcaggttccg tctgttcgtt gcaggcagaa atcggcgttg tcccatctca
     4501 tccggtctat cagttcttct acttggtatg cacggcgcat agattctccc agtgtcaaca
     4561 gtgtgccgta attctcttcc gcatcttggc ggataatagc tgcccgacgg gaaaccgtca
     4621 ggcaactgtc attcttcatc gtttttttca tacagatttc tttgtgctga aatgtgagca
     4681 tttcagttct tgttagtggt gtaaatgtag tgaatttact tgactttaca aaggataaaa
     4741 ttacttatat aatagatgat tagttaaata aatggaataa aatattttgt attttcattg
     4801 tctgaatata ggctttaaag agcttatgga ggagtttaaa gaaagctgtg gagggaatgg
     4861 aaataggctg caaagggcaa aggacggccc tctttatcct ctgtagtgaa aaccgtgcaa
     4921 taatgttcca catggtaatt ggtacactga taattattca ccattgaaac cttttgcgca
     4981 gcctttttat ccaactgtcg ctacgtataa cgttgttatt ctgtccaatc gcttttttca
     5041 aatcccggat tcgttcgttt tgtctcttca ttgctgcctg tatttcgttt atcaacgtat
     5101 ttatttcctt ctgcagctga atttcctttt ctttcaattg aataatgtgg gcgtatttct
     5161 cgcagaccat cgttttgtct atgcacagtt gttccagcgt atcaatatat tctgctgtaa
     5221 tgccggcttt acttcggcga aagagttcca gaatacattc ttcgtcaacg ttcggaacat
     5281 tgtctatgta taacataggg aattgtccca tttccaccca aagcaggatc gcttcttttt
     5341 cgatgtgata cttaatcact gctttttcta cactaatcca ttttggcata tcgcttttgt
     5401 tttaatgtgt tataaaaaag gagtaaataa cgtattgtcc ggagaggtgc aacgaacacc
     5461 cacgattttt atgatttcgg tcggctgggg aattggttgg ggtataagga ttgttgaaac
     5521 cgaccggata caataaaagc gtgagtgctg ttgtaccatt atctaaactt aaggcttagc
     5581 aacacccttc accagataat gataaacaac agacacccac gccaaacgtt tatatataac
     5641 aaatctctaa tcgatatgtt gatatacgac tatctacgtg gagtatctgt tgtatcatct
     5701 ctcggtgtga aaaaactgct aatttttaag tttgagagac aatacgttat ttactccatt
     5761 aaggaataaa aaaacgcttt tgcctgtttc atcacgctga tgggcagaaa gcgtgtgaca
     5821 aagatatatg tttttttcgg aataggatgg aaaagaggaa ataaatgcag gaaatatggt
     5881 atgagaatag agagtatggt ataaagatgg taaatatgct atacgggtgg caaatataat
     5941 gtgatgataa aaaggaggga gccaaaagta aaaccatcta ttagattgat attatttagg
     6001 tacggattac acggatttcg cggttttagt ctaatggaac cgtgaaaccc gtgtaatccg
     6061 tgcctaaatg aaagccataa aagtcttttg acctcgtatt gtctttccgt gcaattcttt
     6121 ttttagctgc gatttctttt gggctttccg gagaagatag tcagttcaag aattgcaaag
     6181 atgatttccg ttgtggtata tccggtaaat gaatattcta aattttcatt ttcggagaag
     6241 tatttgagat aaacgattgg agtgccattg tggaagtcga gaaaaaggta agaagtataa
     6301 tcatagatgc caagatcggc aaactcgttc agaatcgctg tgttgaaaat cgtgcattgg
     6361 cctgtctttg attcatttcc ggacatttcg aatctgcgat gttcttttgc gagatcgtct
     6421 ttattcacat gcctgaattg ttcttgcagt tctttactga aagaaaggcg ttgtctgatg
     6481 aaattaaaaa cttcttcctt tgtcatttgt tttaaatcgg ttatttccat tttttattaa
     6541 ttattggggt aaaggtactt tctttatttg gtaataaatc ggatttagtc atatttcttt
     6601 tatttatttt tcggcttata accctaaaag aatctgaatt tatggattta tttagggtta
     6661 taaccctaaa aactttccga aaatagtata tctttgtgct tataacccta aaaacttttg
     6721 aatatgatta atcgtgaaca gtatatggaa caaattgttc cttttataga taagccgttt
     6781 gtaaaagtga taacgggtat tcgtcgcagt ggaaagtcgg tagtgctgcg tctgattcgt
     6841 gacgaactgt tgaggagggg agttcgtgaa gaacgtatca tctatctgaa ttttgaaagt
     6901 tttcagtgga tagatttgaa agaggcgaag gctttgtatg cttatattcg gggacaggcg
     6961 ggagatgcgg gtaaatatta tattctcttg gatgaaattc aggaagtgga cggttgggaa
     7021 aaagtggtca actcacttct ggtagatttg gatacggata tttatgtgac cggctccaac
     7081 tcacgtatgt tatcgtccga actggcaact tatttaacgg gacggtatgt cgctttccat
     7141 gtcatgacct tgtcttttag agaatatctg actttccatg acttgcaggc caatgatccg
     7201 acgctcaacc ggaaggagga atttcagaaa tatctccgta tgggaggatt tccggccata
     7261 catactgccg attatggata tgaggctatc tataaaattg tctacgacat ctattcttct
     7321 gtcattcttc gtgacacggt gcagcgtcac aatatccgga atgtggaact gctcgaacgg
     7381 gtagtgaagt ttgttttcga taatataggc aataagctga acgctaaaaa tatagccgat
     7441 tacttcaaaa gtcagcaacg gaaggtggat atgaatacca tctataatta tctgaatgca
     7501 ttggaaagtg cttttatcat tcaacgtatt ccccggtatg atattaaagg aaaggaaatt
     7561 ctgcagacga atgaaaagta ttttgtaagt gacctttctt tgatttattc cgtgatgggc
     7621 tatcgtgacc ggttgattgc aggtatgttg gagaatctgg tctgtctgga gttgaaaaga
     7681 aggggttatg aagtgtatgt aggcaaacag gatgataaag aagtggattt tgtagccatc
     7741 cgtcgggaag aaaagattta tgtgcaagta acgtatcagt tagcttcaca ggccactgtt
     7801 gagagggagt ttgctccttt gctcgccatt aacgaccatt atcctaaata tgtagttagc
     7861 atggacagct tgtggcagga taatgtggag ggtgtcaggc atcgtcatat agccgatttc
     7921 ttgttggatg atgcttgacg ttaaggaata tagaaaacga aaaagaggaa attctctgcg
     7981 agaatctcct cttttttcat ctttcacgaa agatcgaatt atttcttctt acggtcaccg
     8041 taacggctca tgaacttgtc aacacgacct gcagtatcta ccaatgtaga tttacctgta
     8101 tagaacgggt gagaagtgtt tgagatttca atcttcagca acggataagt ttcaccttcg
     8161 aattcgatgg tttctttagt tgctacagtt gatctagaca aaaacatgtc accatttgac
     8221 atatctttaa atactaccgg acggtatgat tctggatgaa ggcctttttt catttcagta
     8281 tctgtttttt taatttatat tctgttacta ttttggtaag aaatagtgta atggtcattt
     8341 tcagagcgca aagataatgc ttttctgtga aatagaaaaa ggttttctaa aatttctgat
     8401 ttctaattta tgatttctga tttgctatgc agattttggt gattaaatga atgaaaaatg
     8461 aggtataaat aaggtataaa taaggagata taaatccgaa ggcatcaatc agaattcaga
     8521 aatcataaat cccaaagttt gcaaggtgga cattacaatc taatgtcaca ctcgtattcc
     8581 tgctaaattt tgcagtctga tttaaacctt tttctactat atttttcttt ccgatgttcg
     8641 ttattcgatg gataatgctt acttttgcgt agaattttta ttcactaaca ataaacttta
     8701 aacaaaatgg taaattacaa agatttagga ttggtaaaca caagagaaat gtttgctaag
     8761 gctatcaaag gtggatatgc tatcccagca ttcaacttca acaatatgga acaaatgcag
     8821 gctatcatca aggctgctgt tgaaactaaa tctcctgtga ttcttcaggt ttctaaaggt
     8881 gctcgtcagt atgctaacgc tactttgttg cgttacatgg cacagggtgc tgtagaatat
     8941 gctaaagaat taggctgcgc acatccggaa atcgttcttc accttgacca cggagataca
     9001 ttcgaaactt gcaaatcttg tatcgattct ggtttctctt cagtaatgat cgatggttct
     9061 caccttcctt acgaagaaaa cgtagcattg actaagaaag ttgttgaata cgctcaccag
     9121 tttgacgtaa ctgtagaagg tgaacttggc gtattggctg gtgtagaaga tgaagtttct
     9181 tccgaccatc acacatatac tgaccctgaa gaagtaatcg acttcgctac tcgcactggt
     9241 tgcgactctt tggctatctc aatcggtact tctcacggtg cttacaagtt tactccggaa
     9301 caatgccaca tcgacccgaa gactggccgt atggttcctc ctccattggc tttcgaagta
     9361 gtggacgctg taatggaaaa acttccggga ttccctatcg ttcttcacgg atcatcttca
     9421 gttccggaag aagaagtgga aactatcaac aaatatggtg gtgcactgaa agctgctatc
     9481 ggcattccgg aagaagaatt gcgtaaagct gctaagtctg ctgtttgcaa aatcaacatc
     9541 gactctgact ctcgtctggc tatgactgct gctgtacgta aggtattcgc tgaaaaaccg
     9601 gctgaattcg acccacgtaa gtatcttggc ccggctcgtg acaatatgga aaaactgtac
     9661 aagcacaaaa tcatcaacgt gctcggttct gacaataaat tggcacagta ataatctccg
     9721 gattattcca taaataaaag aaagaggctg ctccggtttg aacactggta gcagcctttt
     9781 ttatgacgtt taatcgtttc tgaacggagg gaagataaca ctatggctgt aattaaagaa
     9841 cacccgtgtc acaactgaat gtaacacggg tgttcttatc tattataata atgtttctta
     9901 catcaagaat ccaagcagga taccggcagc aacagctgaa ccgatcactc cggcaacgtt
     9961 cggacccata gcgtgcatca gcaaatagtt ggtcgaatcg tattccaaac caatcacttg
    10021 tgagatacgt gcagagtcgg ggacagcaga aacccctgca ttaccgatca atggattgat
    10081 cttgttgccc ttcttcaaga agatattgaa tatcttaacg aagattacac cggatgcagt
    10141 tgcaatgatg aatgacaatg caccgagggc gaaaatcttg atagaatcga gcgtcaggaa
    10201 ttcggaagct tgcgtagaag cacctactgt cagacccaac aggatagtga ttgtatcaat
    10261 caacggacca ctggcagtat tagccaaacg gcgggttaca ccactttctt tcaacaggtt
    10321 accgaagaac agcataccca gcaaaggcag accggaagga accaggaaac aagtcagcaa
    10381 caaaccgatg atcgggaaaa tcaccttctc cgtgtgagaa acggcacgcg gcggtttcat
    10441 gcggatgaca cgttcgttct tggtggtgag cagacgcatg ataggcggct gtatcaccgg
    10501 aactaacgcc atataggagt aggcggacac cgcaatggct cccatcaggt taggtgctag
    10561 cttggaagaa aggaagatgg ccgtcgggcc gtctgctcca ccaatgatac cgatagcacc
    10621 ggcttgcatc gggtcgaagc ccatttctag cgcgatcata taagcaccga agataccgaa
    10681 ttgtgcagct gcaccgatca gcatcaattt tggattagag ataagtgccg agaagtccgt
    10741 catggcgccg atgcccaaaa agatgagcgg cggataccag ccggaggtca ctccctgata
    10801 caatatattc aatacagaac cttcttcata aataccgact ttcagcccgg catccatatt
    10861 aaaaggtatg ttaccgatta atataccgaa accgatagga atcagcagca ttggttcgaa
    10921 ctctttggct attgccaaat agatgaatac caagccaacg agaatcatga ctacatgccc
    10981 taccgtagca ttggcaaagc ctgtgtatgt ccagaagtcg gccaggttat ttcctaaaaa
    11041 gtttataaaa tctcccatat tattcaataa ttacgaggtc attaccttca agaacagagt
    11101 ctcccttgtt gacgttgatg gcagtaatct taccgtcctt atccgcattg atattgtttt
    11161 ccatcttcat ggcttccaat atgataatgg tctgtccttt ctttacagta tcgcctacat
    11221 tcactttgat gtcgaggatc acacccggca acggagattt tactcctgat tttccggtag
    11281 acggagcggt cggtttcact acttgagtag gagcagcagg agcattaggc atcgggcgta
    11341 ctgtcacggg tttcgcaaca ggcttcggct gtttctccat ttctacttta tagtgtgtac
    11401 cgttcacttc tacatgagcg atgttgtctt caatatctcc gatggttact ttatatgagt
    11461 taccgttgat tttatattta tattctttca tcgtttttac tttttaaaag gtgacttact
    11521 ttctgggagg agtttcacgc aaagtgtaaa tcttcgaact ccatggtgag tagctgcgtt
    11581 ttacgcgggt gatggtcagc accgtttctt ctacgtcgtg cacctcatcc tgcatttcgt
    11641 gtaatgccat agaaatagca gcgtatactt cgcccggagc ctgtgacagt tccttagctt
    11701 catgcttgtc aatgccttta gatttcatag cgttgcgctt gctcaaatta acagctactt
    11761 ttcctacaat cttaaaagca ataaagagaa gaatcaatcc gcagaatact acgctcatgg
    11821 cagaaatgga cattccaacg ccatcagcat cgtgttcttc aaacttttcc atcttggaat
    11881 tgctgtcaag agtcttgttg ttggtgctcg gagtcacgta tttgtcaccg cttccacttt
    11941 ttacttccca ttcagctgcc ccgtcgctta cacgagcgta tgattggttg ggaccgagcg
    12001 cgcctgcggg cactacaatc tggtcgagca actttttgcc ggagtcgaac agaccaaccc
    12061 aattagctgt ttccggattc agcttgaagc tggtatggaa agtaccacgg ttaggttcgc
    12121 catctgccca gaatagtgca tgttggcgtg gtttcactaa agtaagtata tcacctttcg
    12181 ggataaaata agtaactgta tcgcccggtt ggctacttac tttcagcaag caagctgcca
    12241 ggtcggcgct accgaatgat ttattgaata tttcaatcca tgcgctgtgc aatccgtaat
    12301 cgtcctgaaa attactctga ttgtctatca ggatttcgtt tagcaccagc ttattgttcg
    12361 acttttgctc tccacaagaa gtcaaaccaa tcagcaacag caaagaaagg aatattccga
    12421 ttttggtttt gttcataatc gttcttgttt taatgtgaaa agtaggatta caacggaata
    12481 ttaccatgct tcttagccgg attactcaat ttcttagtct gcaactgctg caaagcacgg
    12541 ataacacgga aacgtgtgtt gcgcggttca atcacatcgt cgatgtagcc atatttagct
    12601 gcattgtaag gattggcgaa caatttcgtg tattctgctt ctttctctgc aaggaattga
    12661 gccgggtttt cctgatcttt ggcttcgcgt gcgtacaata cttctactgc tcctgcacca
    12721 cccattactg cgatttcggc agtaggccat gcgtagttca tgtcaccgcg aagttgctta
    12781 cagctcatca cgatgtgaga accaccgtag gatttacgca atgtgatagt aaccttaggc
    12841 acagtagctt caccgtaagc atacaacagt ttagcaccat gaaggataac gccattgtat
    12901 tcctgacctg ttcccggaag gaatcccggt acgtctacca acgatacgat aggaatattg
    12961 aatgcatcgc agaaacgaac gaaacgtgca cccttacgag atgcgttact atcgagcaca
    13021 ccagccagat acttaggctg attagcaacg atacctaccg attgtccgtt gaagcgggcg
    13081 aaaccgatga tgatattctt tgcataatct ttctggattt caaggaattc accgttgtcc
    13141 acaatagcgc cgatcacttc gtacatgtca tacggtttag tagggctgtc ggggataata
    13201 tcgttcaaag aatcttccag acggtcgatt gggtctgtgc aatctacata aggagcttct
    13261 tcaaggttgt tttgaggaat atagctcaac agtttgcgaa tcagttcgaa accttcttct
    13321 tctgtttggg cggtgaaatg agtcacaccc gatttagtgg agtgaacgct tgcgccaccg
    13381 aggttttcct ggctaacgtc ttcacctgta acggtcttca ccactttcgg tccggtgagg
    13441 aacatataag aagtgccttc catcatcagt gtgaagtcgg tcagagccgg agaataaaca
    13501 gcaccaccgg cacaaggacc gaagataccg gaaatctgcg gaataacacc tgaagcaagg
    13561 atgttgcgtt ggaagatttc tgcataacct gccaaagcgt tgataccttc ctggatacgt
    13621 gcaccacccg agtcgttgat accgatacag ggagcgccca tcttcatggc ttgatccatg
    13681 attttacaaa ttttcaatga catcgtttct gacagtgaac cggcagaaac agtgaagtcc
    13741 tgtgcgaaca catataccag acgtccttcg atcgtaccgc agccggttac tacaccgtct
    13801 cccgggtaat gttttttctc catgccgaag ttcgtgcatc tgtgctcaac gaacatgtcc
    13861 atttcttcga agctaccctc gtcaagcagc atagccagac gctcgcgtgc tgtgtatttc
    13921 cctttttcgt gttgcttcgc aattgctttt tcaccgcctc cgatacgtgc tacggcacgg
    13981 cgttcaataa gctctttaat tttttcaagt tgattactca tgagttcttg ttagttttag
    14041 agtttatgat taatgttcgc agagttctgt taacacaccc aaagttgatt tcgggtgaag
    14101 gaaagcgata ttcaaacctt cagcaccttt gcggggagct ttgtcgataa ggcggatttc
    14161 tttgccttct gcctctgcca gcgcattggc tacgccatct tctacagcaa atgcgacgtg
    14221 gtgaacgcct gcacctttgt tttcaatgaa tttggcaata gtactctccg ggcaagtagg
    14281 ctccaacagt tcaatttttg tttcgcccac ttttaaaaaa gcagttctta ctttctgatc
    14341 ttccactgtt tcaatgttgt aacacttcag acctaataca ttttcgtagt aaggaagggc
    14401 ttcttcgatg ctttttacag caatgcccag atgttcaatg tgtgaaatct tcataactat
    14461 acttttttta tttggtttta aatctgtgct tataaggcat aaaacagcac aaagaaagac
    14521 atttcttatc taataaagaa atatttctgc atttaattat tggattatta aacagaaaaa
    14581 atggtgggaa aggagcataa aacattgttt tgtaatcttg agattacatt tagacataaa
    14641 acttgactaa gagtttattc agccaactcc aattgacgcg gaaccaacgg cgggtactgc
    14701 tttgttttcc tccgaagcga agaacgaaat cacgataacc gtgtttacgg aacggaagtc
    14761 ctacatccat aaattccatg tggcggaatc cccgttggtg tgcgtcttcc aatgctttcc
    14821 aaacggctag cacacccgga tattgaagtg cgtaagtctt tct
//
