LOCUS       gnlProkkaPANEFEJP_7    15201 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PANEFEJP_7.
ACCESSION   gnlProkkaPANEFEJP_7
VERSION     gnlProkkaPANEFEJP_7
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 00:13:37
            Original ID  :: gnl|Prokka|PANEFEJP_7
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15201
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15201
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4850:5201]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4851..5201
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15201
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15201
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2..169
                     /locus_tag="ctg7_1"
                     /transl_table=11
                     /translation="MVACEDSFRQAIYVAIDVFRNRQREKVARANPLRKQYYEKRDDSD
                     KLKLDTVDED"
     CDS             179..1420
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg7_2"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             1407..1934
                     /locus_tag="ctg7_3"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             1940..2713
                     /locus_tag="ctg7_4"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTAPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGYELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             2720..3115
                     /locus_tag="ctg7_5"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPAAETPAPAAE"
     CDS             3365..4753
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_6"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             4851..5201
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_7"
                     /sec_met_domain="PqqD_RRE (E-value: 7.2e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.6e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(5220..5504)
                     /locus_tag="ctg7_8"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(5541..6608)
                     /locus_tag="ctg7_9"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKVAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKMPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(6682..8193)
                     /locus_tag="ctg7_10"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHTLTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             complement(8629..8745)
                     /locus_tag="ctg7_11"
                     /transl_table=11
                     /translation="MRNTLKYYENKAAFEPKYGRTYEKYRFEKVFLIRYLFD"
     CDS             9416..9640
                     /locus_tag="ctg7_12"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             9834..11378
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 46.8; E-value: 2.5e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_13"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             11419..11955
                     /locus_tag="ctg7_14"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             12015..12584
                     /locus_tag="ctg7_15"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAIDKL"
     CDS             12674..13828
                     /locus_tag="ctg7_16"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVVLLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYEEDGDDDIDYEYEEDWEEE"
     CDS             13825..14637
                     /locus_tag="ctg7_17"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLDAYPEVAHFVTTRHGGISTGAYGSFNCSP
                     YTNDSCVNVNRNQNWLFQCMNHQIKELFIPEQSHGCASLIINESFFKESLERRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSHVMDNMTQKF
                     GTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNRRVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRTLSGIMIRK"
ORIGIN
        1 gggagtggct tgtgaagatt ctttccgcca ggcaatctat gttgccatcg acgtgttccg
       61 taatcgtcag cgtgaaaaag tggctcgtgc caatccgttg cgtaaacagt attacgagaa
      121 acgtgacgat agtgataaac tgaagctgga tacagtagac gaagattaaa aacgagtgat
      181 gacgaaagca gagatacaac aagtgaaaca gcgttttggt attattggaa atactgaagc
      241 attgtcgcgc gccatagatg ttgccattca ggtagctcct accgatttgt ctgtgctgat
      301 taccggagaa agtggagtcg gaaaagaaag ttttccgcag attattcatc aatatagccg
      361 gaggaagcac ggacagtata ttgctgtcaa ctgtggcgct attccggaag gtacgattga
      421 ttccgaactg ttcggacatg agaaaggtgc gtttaccggt gcgattggcg aacggaaagg
      481 gtactttggc gaagctgacg gtggtactat ttttcttgat gaagtagggg agttgccgat
      541 gtctacccag gcacgtttgc tccgtgtact ggagagtggc gagtttatga aagtaggttc
      601 gtccaaagta caaaaaacgg atgtgcgtgt ggtggcagct accaacgtca atctgacaca
      661 agcgattgca gaaggacgtt tccgtgaaga tttatattac cggttgaata cggtgcctat
      721 ccaaataccg cctttgcgtg aacgtggtga cgatgtactt ttgttgttcc gtaagttttc
      781 cgcagacttt gcagagaaat atcggatgcc tgctattcag ttgacggagg atgcgaagaa
      841 agagttgtta gcttacccgt ggcccggaaa cgtgcgtcag ttgaagaaca tcaccgagca
      901 aatatctatc attgaaacca atagggagat ctctgctgct atcttgcaga attatcttcc
      961 cgcacaaaat acgcaacgtc ttcccgcgct gatgggaacg cgtgagagta aaggctttga
     1021 gagcgaacgg gagattcttt attccgttct gttcgatatg cgccaggaag tggcggagct
     1081 gaagaagatg gtgcacaacc tgatggcgga acgtgccgga caggtggggc aggtaggaca
     1141 aatgggaacg gtggttacta ctccggtagt gacggcgcat caaccttcgg tacctgctat
     1201 tattcacacc atgcagccta cggtttgcaa ggatgatgat gacatacaag acacggaaga
     1261 atatgtagaa gaatctcctt tgtcactgga cgaagtggag aaagaaatga tacgcaaggc
     1321 acttgagagg catcatggaa agcggaagag tgcggccaag gacttgaata tttccgagcg
     1381 tacactttat agaaaaataa aagaatatga attggattaa gaaaataata cgccctttgt
     1441 tactgttcgg cttgccgttg gtagtcattg cgtgcactgt ttcctataag tttaacggat
     1501 cgtctatcaa ttatgataag gtaaagacca tttcgatagc cgacttcccg atcaagtcgg
     1561 agtatgtata tgctccgttg gcaaccaaat tcaatgagga cctgaaagat atcttcatcc
     1621 ggcagacccg tctgcaactg ctcaagccga atcagaatgc ggacttgcag attgacggag
     1681 aaatcacagg atacaatcag tacaaccagg cagtatctgc cgacggttac tcttcggaga
     1741 cgaagttgac tattaccgtc aatgtacgtt ttgtcaacaa caccaatcat gccgaagact
     1801 ttgaacaaca gttttctgcg ttccgtacct acgactctag ccagttgctg actgccgtac
     1861 aggacggatt gattgctgaa atgtctaaag agatcaccga ccaaattttt aatgcaactg
     1921 tagcaaactg gtaatataaa tgacttctgt taactttcaa caatggattc agcatcccga
     1981 gacgctgaat agggatactt tgtacgaact gcgcaatctt cttgcgaggt atccgtattt
     2041 tcagtcactt cgtctgctgt atctgaagaa tctgtatatt ctccatgata ttagtttcgg
     2101 tggagaactg cggaaagcag ttctttacat tgcagacaga cggcagttgt tccggttgat
     2161 tgaaggtgac cgctatgatg tgcaagcacg gaaaaaggga gtacctctca cggaggtact
     2221 gaaagacgaa ccatctgtag accgcacatt agcattgatc gacgctttct tgtccacagc
     2281 ccccgaagaa gtgactgccc gcaccagctt cgactattcg atggattaca cctcttatct
     2341 tttggaggag actccggcca cggaacagcc ggccgaagaa acgcccaaac tcaaaggcta
     2401 cgaactgatt gacgacttta tagaaaagag cgagagcgac tctcccctct gcatgaaacc
     2461 tttaagagaa gaaatgccat cttcgccaac ctcttcggac gaacttaccg aagaagaaac
     2521 gatgaaggaa gaagaggaag atgacagctg ttttacggaa actttggcaa aaatctatgt
     2581 taaacagcaa cgatattcaa aagctcttga aataattaaa aaattaagct tgaaatatcc
     2641 aaaaaaaaat gcttactttg cagaccaaat cagatttttg gagaaattga ttattaacgc
     2701 taattcaaaa taactaaaaa tgtacttatt attcgttatc ttaatggtta ttgcagcctt
     2761 gttgatgtgt ttcatcgtgc tgattcagaa ctcaaaagga ggcggacttg cttctggttt
     2821 ctcttcatct aacgccatca tgggcgtgcg caagactaca gattttctgg aaaaagcaac
     2881 atggggctta gctatcttca tggtggtaat gagcattgct actgcttatg tagttcctcg
     2941 ctctgctgtt gctaaagacg cagtgttgga acaggcacag aaagaacaac agactaaccc
     3001 gtataactta cccgcaggta cggctgcgcc gcaaactgaa gctcctgcta ccaatgcacc
     3061 tgctacagaa actccggcac cggctgctga aactcctgct cctgcagcag agtaattcac
     3121 tctgtcgtca ggtaagactt tggggtaaaa ccattaatgg gaaggtgcag acgaatgctg
     3181 catttctttg atatttaagt gcggattacg cagattacac ggattttcaa tcttccgcgt
     3241 ggtcagtgta atccgcactt aactttttct tgtaaaaaca atctcttttt gatagaaaca
     3301 aacgagattt aactaccttt gttggtcgta tgaagattat taactactat ttttaaatat
     3361 aacaatgaca gaacatttga aacagaaatt gaatgactcc gccgtactcc gatggagtgt
     3421 tctagcatta gtcgcattta ctatgctatg cggctatttc ctcaccgacg taatgtctcc
     3481 tctaaaaccc atgcttgaga aagaactact atgggacagt ctggattatg gtttcttcac
     3541 aagcgcttac gggtggttta atgtattcct gttgatgctg atcttcggtg gtatcatttt
     3601 ggataagatg ggagttcgtt tcaccggaat gggggcttgc ttattgatgg tgtttggttg
     3661 tggattgaaa tactatgcga tttctactac ttttccggaa ggtgccatgc tcttcggatt
     3721 caaaacacag gtaaccctgg ctgcattggg gtatgctatc ttcggtgtag gtgtggaaat
     3781 tgccggtatc acagtttcca agattatcgt aaaatggttc aagggtaagg aaatggcatt
     3841 ggctatggga cttgaaatgg ctacggcacg tatcggaaca actctggcaa tggtgcttac
     3901 ggttcctttg gccgactttt tcggatctac ggatgagagt ggcacattcc ataccaatat
     3961 tcctgctcct attctgtttt gtctgattat gttgtgcgtg ggtacgattg ctttcttcct
     4021 ttatactttc tatgataaga agttggatgc ttctttggat gcagagggat tggagccgga
     4081 agagccgttc cgtatgaaag atattgtgta tatcattacc aataaaggat tctggttgat
     4141 tgcattacta tgtgtattgt tctactcggc tgtattcccc tttatcaagt atgctgccga
     4201 cttgatggtg cagaagtata atgtagatcc gaagttggcg ggaacgattc ccggattgtt
     4261 gccgattggt gcgattatcc tgactccgtt gttcggctcg ctttatgacc gtatcggtaa
     4321 gggagctacg ttgatgataa tcggatcagt gatgcttatt tttgtgcata cgatgttcgc
     4381 tctgcctata ctgaatatat ggtggtttgc tactatcatc atgattatat tgggatttgc
     4441 cttctcgttg gtgccttcag ctatgtggcc gtctgttccg aagattattc cggaaaaaca
     4501 gttgggtacc gcatacgcat tgattttctg ggtacagaac tggggattga tgggtgttcc
     4561 tttgttgatc ggatgggtgt tgaatactta ttgtaaaggt ccggtagtag acggtgcaca
     4621 gacttatgac tacacgttgc cgatggctat ttttgctctc tttggtgtgc ttgctctgat
     4681 tgtggctttg atgttgaagg cagagaacaa gaagaaggga tacggtctgg aagaggcgaa
     4741 tatccaaaag taactaggaa attcaatacc taaagtaaca aaggaatttt gtatcaaggt
     4801 gtaaacaaaa gggtatcagt atgaatactc tgaaataaaa aataagaagt atggctgcca
     4861 aagagaaaat caacctgtta gaggtcattc cctgtcgcag tgaacatatt acagcagaaa
     4921 gggaagggga gacaattgtg ctctcctttc cccgttttaa atatccgtgg atgcaacgct
     4981 tccttgtgcc gaaaggaatg tcgaaagaac ttcatgtgaa attggaagaa cacggtacgg
     5041 ctgtatggga actgatagat ggaaaacgca atgttcgtga gattatagaa aaactcgcag
     5101 accactttca aaatgaagag ggctacgagt cgcgtgtatc ggcttatctt tctcaaatgc
     5161 agaaagatgg atttataaaa ctggtgatac cagtcgcata aataggaact tattattatt
     5221 tatttgataa atacagccca aagtatgacg gcaattgcta tcaggacccc catgataata
     5281 agcgttcccc aaacaaaata attgctgtct ttctctttct ttttctccga gtcgtggatg
     5341 atacgttcca tttcttcggg agtggtgttg ggtagtggat aaggttcgtt tgcacggttt
     5401 agatgcttca acttatcgtt agcacgttca cgacgtaggc gggaagcttc ccgtccctct
     5461 tttattcggc gtatcatgtc gaatgcatgt ccttcaccaa ccatattctt tgttttttag
     5521 aagttcactt ccttgttttt ctatttccct tcttctctgt ccactttgag caatcctccc
     5581 gtattcggat caaaataaac tttgatggta gaattcttat tgaacaaaac cggagccaga
     5641 tattctatca caccgaattg agtaatagga agctcacctt cgtaaagttt ctttttaccg
     5701 tcggtcagtg taaccatagc ttgtccgggt acgttgtagg cgattccatc caaatctttc
     5761 ttcttcttac cgtcttcctg tggcatcttg acagatttca ggtctttcag actgatataa
     5821 aacggagttc ctgccaaatc attgttggca actacaccta acttcttcga gaagcggaaa
     5881 gcaacttcat tgttgaattc cttgtcaggg gtaaggcgga cagtgaatgt tctttcttct
     5941 ttgttgcagg tgccggagaa catttgcgtc atggcttctt cctgtgcatt cagattgtcg
     6001 agcataatct taagctgtgc tccgtctgaa ggcatattgt cagcctgtcc gcgcaataag
     6061 gcatttttgc tttcgcggat gttatagatt tctttagcca ccagctcggc catcttggcg
     6121 gtagagctag ccatcagaat ctcctcggtc aggaattcgc gaggattcgc tttcttttgg
     6181 aggactgcgg gagcgggagc aacttttttg cctacactgc tattgctgta aggaacattg
     6241 atcgttttca caatgccatc ctctgtcagt tccataagcg gtgctactgt cttatccttc
     6301 aattttacga aatacgtagt ttcgctgttg ggcacaccta cggatttcac ttttacgcta
     6361 gccagttccc agtactcttc aggatcggcg gagacgttgg tcagtcgcag gtaacgatca
     6421 gcatatttgc tgaattctcc cggagtatag ttgactttgt tggcttttat ttcaagttct
     6481 atttgggttt tgggaagact gtaaaccact ccatagtctt ttcctcgggt aacccctgtc
     6541 agtacttcgg tttgtgcata ggcggacgtt gtcataagta gtcctgctgc tataattaac
     6601 tttttcatat tcggttcttt tttaactggt tttgaaaaca aagttaatga agttattgaa
     6661 aaaactgtaa gttcttaact tttattcgct tacaagtcgc catgctgtcg gcagacaggt
     6721 gataatatcg cttgcgatca ttccgatcat tccttgcttc ttttgagcga catcgcccgc
     6781 caatccgtga atgtaagtgc cgattttagc ggcttcttcg gtgggataac cttgggcaag
     6841 cagtgccagg attactccgg tcagtacgtc accgctacct ccggttgcca ttcccggatt
     6901 tccggttggg ttgaagaaac atttaccttc tggggtgata atggcggaat aggctccttt
     6961 taaaataatg tgaacatggg cggcacgagc caattcgcaa gccttcatca gacgttcgta
     7021 agagtcttgg catttgccgg tcagacgttc cagttctttc ggatgcgggg tgaggatgga
     7081 acccttcggc aggtgggtaa gggtatggcg gtggttggca aggatattaa gtgcgtcggc
     7141 atccactaca acaggagtct ggcaatgttc cagttgctcc aataaggcag cttccgtttc
     7201 ctcgtttcgt cccagtcccg gaccgatgcc gactgcttga tagtcgtccg tgtcggtagg
     7261 tacggcaaaa caggtttcgt tgatgtcggt ttctacgatt gcttcgggta tggaggtctg
     7321 caagatgtcg ttgttgcaca ttggtgcatg aacagtcagc aaccctactc ccgaacggag
     7381 gcaggcacgg gcagcgagaa cagaggctcc tgccattcct tttgaaccgg caatcaatag
     7441 tgcatgaccg aagtttccct tgtgggcaaa ctgtttgcgt ggcttgatga gtgaacggat
     7501 ttgctctatt tccaacattt cgtagttcgt ttccatctct tcaataccgt cttcgctcaa
     7561 ttggatatcc aacaattccc attctccgac aaattctgtg ttttctgcga aaagaaaggc
     7621 gagcttcggc agttgcagac tgaaagttac gtcggcacgg ataatattag cttttacgtt
     7681 gaatgtattt tcttctccca tcagtccgga agggatgtcg atggctacta ccatggcagg
     7741 ggaggaattg atgtatttca ctacggcagc gaatccgccg ctcaacggtt tgttcaggcc
     7801 tgaaccgaat aatccgtcga ttaccagatg gtcgggcgtc agggcgggag gtacgaattg
     7861 ggtactgatc tcgtggaatt ttacttcttc catcatttct accagttctt tattggtctg
     7921 gcagtcgggt gaaagttctc ctttcgtgtt gaagagaaat acctcgattt tatatccttt
     7981 ttcagccatc atgcgggcta cggcgagagc gtctccgcca ttattccccg gtccggcaaa
     8041 gatagtgacc ggcgtttccg tattccatct gtctgtgatg gcttttgtta atacggttgc
     8101 tgcacgttcc atcagatcga ttgatgcaat aggttcgttc tcaatggtat aagcgtccaa
     8161 tttcttgata ctgctgcttg gaaatatttt cattgcgatg ttcttttagt tttcggatta
     8221 caaatgtaca tgattcttct gacttttccc gtttgttgtg ggaagaaaac cataattgca
     8281 acttttaatt catcattagt tctatctttg ggtcagagaa atatctgctt ttgaactatt
     8341 aagtgttaga ataactccgc caaaaaataa ttcaatgcag caccattatg aacttacttt
     8401 tatttctcct gaaaaagatt tctggttctt cgtcaaattt ggtggtaaat tctttatctc
     8461 tttatttcca agttaataat tatccctttt tactcacttt cataagaaaa tataggcact
     8521 gactgaatta gctaaatgag cggagaaaaa cttaccacca aatttgacga agaaccagat
     8581 ttcttcattt catttctcat attctcattg tttttcgata aacgaaagct aatcaaatag
     8641 atatcttatg agaaacactt tttcgaaacg gtatttctca taagttctcc catattttgg
     8701 ctcaaaagcc gccttattct catagtattt cagggtattt ctcatagtca aaagccattt
     8761 gttcttcctt ttttctttca gcctgcctta tttttatcag gaaatgaagc tactatttag
     8821 ataaaatagt ggctttttgc ttgaagatgc tcattggtct cgattgtccc atatattgtg
     8881 ggaaagtttt ccttcaatat acgggaatac tttcccacaa aataagggaa tactttccca
     8941 agccttaggg aatcttttcc cacaatatgt ggaactaaga cactgtgtat ggaagcaagc
     9001 aaaaggaata catagtttta tttattcaat gtcagcttcc ggcacactac actatgagaa
     9061 atgaagcaaa atccgggtta ttttgcgaag aaactatgag aaatacctgt tttaaaatca
     9121 tttctcatag cctatcttat tagtttactg ccacttgttt cttatttatg agaatatgag
     9181 aaatgaaaaa tctttttctg tagaggcgcg gatggaaatt gtgtttagtt tatcgccata
     9241 ccttcttaaa caaattttta atgcggttcc ccttattaag cctttgatta tttgccgttt
     9301 ccgataaaaa tgttatcttt ggagatagat aatgtgcatc acatcatttt ccagtgctca
     9361 caatgaaaat gaattaaaat ctaaataacg gattgtttaa tcttctaaag tttgcatgat
     9421 ggaaaagaca aaaattggct tgaatgccgg gaaagtatgg cgcatcttaa atgaaaaagg
     9481 tgaactttca atgttcgatt tgtgccgtga attaagtttg acgtttgaag acgtagctct
     9541 cgctattggt tggctggccc gagaagacaa aatctttttg aggaaaagag aaggaatgct
     9601 ttttgccagt atcgaaaatg tcgaatttac ttttggctaa ggtggtagct aacctacatt
     9661 taagatggat ctccacttta ttatttacac tgctaaaaaa gtaatgaagt ggatcagtag
     9721 gattttttat gctcgttttt actattcccc ctattattct gtttgataag agaagcatct
     9781 aatctacttt ttctgtacct ttgcacccca taaactacta aacacataaa ttcatgagtg
     9841 cattgaaagg gcatccgaaa ggcctttatt tgattttcgc gacaagcacg gcagaacgtt
     9901 tcagttatta cggtatgcgt gcgatcttta ttcttttcct gacgcaggca ttattgtttg
     9961 acaaagaagc ggcagcatcc atctacggca gctataccgg actagtttat ttaaccccgt
    10021 tgattggcgg atacattgcc gataaatatt ggggaatccg tcgttccgtg ttttggggag
    10081 cggtgatgat ggcagtcgga caattcctga tgtttatgag tgcctccact ttagataata
    10141 caaaccttgc ccactggatg atgtatggcg gactaggctt cctgatcttg ggcaatggtt
    10201 gcttcaaacc cactgtctct tctctggtag gtcagctcta cgaacccgga gacaggcggt
    10261 tggatgctgc atacaccatt ttttatatgg gagtgaatgt aggctctttt gctgctcctt
    10321 tgatttgtgg ttatctgggt gataccggtg atccgcatga ctttaaatgg ggatttcttg
    10381 cagccggaat catgacactg ttcaccgttg ttcttttcga gactcaaaag aataaatatc
    10441 ttttttctcc ttccggagaa ccgattggta ttatccccga tgctaaacgt gaaaagaaag
    10501 aagacaaggc cgaccatatc tcacacccga agatggacaa acgtaccaaa gtacgtaata
    10561 cccttgtaat cacaattctt accattgctt taatagcctt ctttaactat gcatttgaag
    10621 gcgattgggt gagtatcggc atttttaccg cctgcattgt tttccctgtt ctgatcttgt
    10681 tagacggttc attgaccaaa atagaacgca gccgtatttt cgttatctat atagtagcct
    10741 tctttgtcat cttcttctgg gcagcctacg aacaggcggg agcttcttta actctctttg
    10801 cgtccgaaca gacgaatcgt gacattttcg gttgggaaat gccggcttca tggtttcaat
    10861 ccttcaatcc cctgtttgta gttgtcctgg catatatcat gccgggtgta tggggtttcc
    10921 tgaacaagcg aaagatggaa cctgcttctc ctaccaaaca agcgattggt ctgttactcc
    10981 tttctttagg ttatcttttc atctgtttcg gagtgaaaga tgctgttccc ggagtgaaag
    11041 tgagcatgat ttggctgaca ggactttact ttattcatac catgggtgaa atagctttgt
    11101 cgcctatcgg actttcaatg gtaaataaat tgagtccgct gcgtttcgcc tccctgatga
    11161 tgggaatctg gtatctgtct actgccacag ccaataaatt tgcgggaatg ttgagcgggc
    11221 tctatccgga agccggaaaa gtgaagtcaa tctttggtta tcagattgct accatgtatg
    11281 atttctttat ggtattcgtc gtaatgtccg gtgttgcttc gttgattctg ttccttctct
    11341 cgaagaaatt acagaagatg atgcacgggg tagaataaaa aatcgtattt ttgcaaggtt
    11401 atttttaaat taccggttat ggataccatt cagataaaag acaaattgtt taccgtttcc
    11461 attaaggaac aagaaattca gaaagaagtg attcgcgtag cgaacgaaat caaccgcgat
    11521 ttggcaggta agaatccgct tttccttagt gtgttgaacg gttcgttcat gtttaccgct
    11581 gatttattga agcatatcac catcccttgt gaaatctcat ttgtgaagtt ggcgtcttat
    11641 cagggcatca cttccaccgg agtgattaaa gaggtaatcg gcctgaatga agacattgcc
    11701 ggacgtacca ttgtgatcgt agaagatatc gtagacacag gactgacgat gcagcgactg
    11761 ctcgaaacat taggtacacg caatcccgaa gctattcata tcgcttctct gttggtgaaa
    11821 cctgaaaagc tcaaggtaaa cctcaacatt gaatatgtag cgatggaaat cccgaacgac
    11881 tttatcgtag gttacggact ggattatgat ggtttcggac gtaattatcc cgatatttat
    11941 acagtagtag attaatatta aataggtacc agtttaaatg gtaaatagta aatcgttaaa
    12001 ttgtaaataa caaaatgttg aacatcgtaa ttttcggtgc tccgggttca ggaaaaggaa
    12061 cacagagcga acgtatcgta gaaaagtatg gaatcaatca catctcgaca ggagatgtat
    12121 tgcgtgctga aatcaagaat ggcacagaac tgggtaaaac agctaaaggt tacatcgacc
    12181 aaggtcaatt gattcctgat gaattaatga ttgatattct ggcaagcgta ttcgacagct
    12241 tcaaagatag caaaggtgta attttcgacg gtttcccaag aacaattgca caagcagaag
    12301 cattaaagaa aatgttggca gaaagaggac aggacgtttc tgtaatggtt gacttggatg
    12361 ttccggaaga agaactgatg gtacgtctca ttaaacgtgg caaggattcc ggtcgtgctg
    12421 atgataacga agagacaatc aagaaacgtc tgcatgtata tcattcacag actgctccac
    12481 tgatcgactg gtacaagaac gaaaagaaat accaacacat caacggcttg ggtactatgg
    12541 aaggtatctt cgctgaaatc tgcgaagcaa tagataaatt gtaataatac aatattataa
    12601 ataaataagt cagtagccgg agtgttctaa ttaactgctc taactactga ctactttaac
    12661 tctttaaaaa aatatggctg aatcgaattt tgttgattac gtaaagatat actgtcgctc
    12721 gggtaagggc ggaagaggct ctacgcacat gaggcgcgag aaatattgtc ctaacggagg
    12781 tcctgatggg ggcgatggtg gaagaggagg tcatatcatc ttgcgcggta accgtaatta
    12841 ctggacattg ctgcacttga agtatgaccg tcatgcaatg gccggtcatg gtgaatcggg
    12901 gagcaaagga cgtagtttcg gaaaagacgg tgcggataaa ataatagaag taccctgcgg
    12961 aacggtagtt tataatgccg agacagggga gtatctttgt gacgtaacag aagacggaca
    13021 ggaagtggtc ttgctcaaag gcggccgcgg cggtcagggt aactggcatt tcaagacggc
    13081 cacccgtcag gctccgcgtt ttgcgcagcc aggagaaccg atgcaggaaa tgaccgttat
    13141 catggagctg aaactgcttg ccgatgttgg tctggtaggt ttcccgaatg cgggaaagtc
    13201 aactttgctt tcttccattt cggctgccaa accgaaaatt gccgattacc cgtttactac
    13261 actcgaaccc aacttgggca tcgtttccta tcacggtgga aaatcctttg tgatggcgga
    13321 cataccgggt attatcgaag gtgctagcca ggggaaaggt ttgggactgc gtttcttgcg
    13381 tcatatcgag cgtaattcat tactgctgtt tatggttccg gcagacagcg acgacattcg
    13441 taaagaatat gaagtcttgc tgaacgaact gcgtaccttc aatcctgaaa tgttggacaa
    13501 gcaacgtgtg ttggctgtca ccaagagtga tatgctcgat caggagttga tggacgagat
    13561 tgaacctaca ttgccggaag gcattccaca tgtattcata tcttctgttt ccggtttggg
    13621 tatctcggtg ttgaaagaca tcctttggga agaactgaac aaggaaagca ataaaataga
    13681 ggacatcgtt caccgtccga aagacgtgac ccgtctgcaa caggaactca aagacatggg
    13741 cgaagatgaa gacatcgttt atgaatatga ggaagatggc gacgatgata tcgattatga
    13801 gtacgaagaa gattgggaag aagaatgatt tctcttacaa aacataacga gttgaaggga
    13861 tataagtcat tagatgcata tcccgaagta gctcatttcg taactacacg tcacggaggt
    13921 ataagcaccg gagcttacgg ctctttcaac tgttcgcctt ataccaacga ctcatgtgtg
    13981 aacgtcaatc gcaatcagaa ctggttgttt cagtgcatga atcatcagat aaaggaatta
    14041 tttattcctg aacagagtca tggttgcgcc agtctgatta tcaatgaatc attttttaaa
    14101 gaatcattgg aaaggagacg gctacttctg cgaggaatgg atgctttgat aacgaatgtg
    14161 ccgggatatt gcgtttgtgt cacgacagcg gattgtgttc ctgtattgct gtacgacaaa
    14221 aaacaacacg ttgtggctgc cgttcatgcc ggatggaagg gaacggtgaa gcatattgtc
    14281 agtcatgtga tggacaacat gactcaaaag ttcgggacgc aaggcgaaga tgtaatagct
    14341 tgcatcgggc cgagcatttc gctcgaatca tttgaagtag gcgatgaagt gtatgatgct
    14401 tttgaagaaa gcggtttcga tatgtctctt atttctatga agaagaagga gacaggcaaa
    14461 tatcatattg atttgtggga agccaaccgg attgaattac tgaatcgcag agtgcctgca
    14521 gagcagatag aagtggctgg aatctgtacc tatattcatc atgatgaatt cttctccgca
    14581 cgtagactgg gaatagattc cggtcgtaca ttgtcgggaa taatgattag aaagtaataa
    14641 ttggtgtccg ttattgcagg acgctgatga ttggtttatg ataagttatg tttgaaataa
    14701 aagtatctaa agaaataaaa gacgcatgtc cggtttttgc cggagccgct gtgtatgctg
    14761 ttgtgaaaaa tacagcttac agcgaagggc tttggcagga aatcgacgct tttaccaagc
    14821 aactgacttc cacaacacag atggaagaca tcaaacatca acccgttatc tttgctaccc
    14881 gtgaggctta taaacgttgt ggcaaagacc ccggacgtta tcgtccgtca gccgaagctc
    14941 tacgccgccg cctgatgcgt ggaattcctt tatatcagat tgatacgttg gtagacctta
    15001 ttaatttagt gtctcttcgt acgggacatt cgatcggtgg ttttgacgcg gacaaaatac
    15061 aaggtacgca ccttgaactc ggtatcggca aagcaggaga accgtttgaa ggtatcggac
    15121 gcggtgtatt gaatatcgaa ggattacctg tatatcgcga ttctttcgga ggaatcggaa
    15181 ccccgacaag cgatcatgaa c
//
