LOCUS       gnlProkkaBMAFOOIP_34   15216 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BMAFOOIP_34.
ACCESSION   gnlProkkaBMAFOOIP_34
VERSION     gnlProkkaBMAFOOIP_34
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 04:29:47
            Original ID  :: gnl|Prokka|BMAFOOIP_34
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15216
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15216
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[4865:5216]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4866..5216
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15216
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15216
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             2..184
                     /locus_tag="ctg34_1"
                     /transl_table=11
                     /translation="MIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARANPLRKQYYEK
                     RDDSDKLKLDTVDED"
     CDS             194..1435
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg34_2"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             1422..1949
                     /locus_tag="ctg34_3"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             1955..2728
                     /locus_tag="ctg34_4"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTAPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGYELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             2735..3130
                     /locus_tag="ctg34_5"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPAAETPAPAAE"
     CDS             3380..4768
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_6"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             4866..5216
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_7"
                     /sec_met_domain="PqqD_RRE (E-value: 7.1e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.6e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(5235..5519)
                     /locus_tag="ctg34_8"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(5556..6623)
                     /locus_tag="ctg34_9"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKVAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKMPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             complement(6697..8208)
                     /locus_tag="ctg34_10"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHTLTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             9431..9655
                     /locus_tag="ctg34_11"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             9849..11393
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 46.8; E-value: 2.5e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_12"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             11434..11970
                     /locus_tag="ctg34_13"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             12030..12599
                     /locus_tag="ctg34_14"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAIDKL"
     CDS             12689..13843
                     /locus_tag="ctg34_15"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVVLLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYEEDGDDDIDYEYEEDWEEE"
     CDS             13840..14652
                     /locus_tag="ctg34_16"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLDAYPEVAHFVTTRHGGISTGAYGSFNCSP
                     YTNDSCVNVNRNQNWLFQCMNHQIKELFIPEQSHGCASLIINESFFKESLERRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSHVMDNMTQKF
                     GTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNRRVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRTLSGIMIRK"
ORIGIN
        1 cgatattgca ggcaagggag tggcttgtga agattctttc cgccaggcaa tctatgttgc
       61 catcgacgtg ttccgtaatc gtcagcgtga aaaagtggct cgtgccaatc cgttgcgtaa
      121 acagtattac gagaaacgtg acgatagtga taaactgaag ctggatacag tagacgaaga
      181 ttaaaaacga gtgatgacga aagcagagat acaacaagtg aaacagcgtt ttggtattat
      241 tggaaatact gaagcattgt cgcgcgccat agatgttgcc attcaggtag ctcctaccga
      301 tttgtctgtg ctgattaccg gagaaagtgg agtcggaaaa gaaagttttc cgcagattat
      361 tcatcaatat agccggagga agcacggaca gtatattgct gtcaactgtg gcgctattcc
      421 ggaaggtacg attgattccg aactgttcgg acatgagaaa ggtgcgttta ccggtgcgat
      481 tggcgaacgg aaagggtact ttggcgaagc tgacggtggt actatttttc ttgatgaagt
      541 aggggagttg ccgatgtcta cccaggcacg tttgctccgt gtactggaga gtggcgagtt
      601 tatgaaagta ggttcgtcca aagtacaaaa aacggatgtg cgtgtggtgg cagctaccaa
      661 cgtcaatctg acacaagcga ttgcagaagg acgtttccgt gaagatttat attaccggtt
      721 gaatacggtg cctatccaaa taccgccttt gcgtgaacgt ggtgacgatg tacttttgtt
      781 gttccgtaag ttttccgcag actttgcaga gaaatatcgg atgcctgcta ttcagttgac
      841 ggaggatgcg aagaaagagt tgttagctta cccgtggccc ggaaacgtgc gtcagttgaa
      901 gaacatcacc gagcaaatat ctatcattga aaccaatagg gagatctctg ctgctatctt
      961 gcagaattat cttcccgcac aaaatacgca acgtcttccc gcgctgatgg gaacgcgtga
     1021 gagtaaaggc tttgagagcg aacgggagat tctttattcc gttctgttcg atatgcgcca
     1081 ggaagtggcg gagctgaaga agatggtgca caacctgatg gcggaacgtg ccggacaggt
     1141 ggggcaggta ggacaaatgg gaacggtggt tactactccg gtagtgacgg cgcatcaacc
     1201 ttcggtacct gctattattc acaccatgca gcctacggtt tgcaaggatg atgatgacat
     1261 acaagacacg gaagaatatg tagaagaatc tcctttgtca ctggacgaag tggagaaaga
     1321 aatgatacgc aaggcacttg agaggcatca tggaaagcgg aagagtgcgg ccaaggactt
     1381 gaatatttcc gagcgtacac tttatagaaa aataaaagaa tatgaattgg attaagaaaa
     1441 taatacgccc tttgttactg ttcggcttgc cgttggtagt cattgcgtgc actgtttcct
     1501 ataagtttaa cggatcgtct atcaattatg ataaggtaaa gaccatttcg atagccgact
     1561 tcccgatcaa gtcggagtat gtatatgctc cgttggcaac caaattcaat gaggacctga
     1621 aagatatctt catccggcag acccgtctgc aactgctcaa gccgaatcag aatgcggact
     1681 tgcagattga cggagaaatc acaggataca atcagtacaa ccaggcagta tctgccgacg
     1741 gttactcttc ggagacgaag ttgactatta ccgtcaatgt acgttttgtc aacaacacca
     1801 atcatgccga agactttgaa caacagtttt ctgcgttccg tacctacgac tctagccagt
     1861 tgctgactgc cgtacaggac ggattgattg ctgaaatgtc taaagagatc accgaccaaa
     1921 tttttaatgc aactgtagca aactggtaat ataaatgact tctgttaact ttcaacaatg
     1981 gattcagcat cccgagacgc tgaataggga tactttgtac gaactgcgca atcttcttgc
     2041 gaggtatccg tattttcagt cacttcgtct gctgtatctg aagaatctgt atattctcca
     2101 tgatattagt ttcggtggag aactgcggaa agcagttctt tacattgcag acagacggca
     2161 gttgttccgg ttgattgaag gtgaccgcta tgatgtgcaa gcacggaaaa agggagtacc
     2221 tctcacggag gtactgaaag acgaaccatc tgtagaccgc acattagcat tgatcgacgc
     2281 tttcttgtcc acagcccccg aagaagtgac tgcccgcacc agcttcgact attcgatgga
     2341 ttacacctct tatcttttgg aggagactcc ggccacggaa cagccggccg aagaaacgcc
     2401 caaactcaaa ggctacgaac tgattgacga ctttatagaa aagagcgaga gcgactctcc
     2461 cctctgcatg aaacctttaa gagaagaaat gccatcttcg ccaacctctt cggacgaact
     2521 taccgaagaa gaaacgatga aggaagaaga ggaagatgac agctgtttta cggaaacttt
     2581 ggcaaaaatc tatgttaaac agcaacgata ttcaaaagct cttgaaataa ttaaaaaatt
     2641 aagcttgaaa tatccaaaaa aaaatgctta ctttgcagac caaatcagat ttttggagaa
     2701 attgattatt aacgctaatt caaaataact aaaaatgtac ttattattcg ttatcttaat
     2761 ggttattgca gccttgttga tgtgtttcat cgtgctgatt cagaactcaa aaggaggcgg
     2821 acttgcttct ggtttctctt catctaacgc catcatgggc gtgcgcaaga ctacagattt
     2881 tctggaaaaa gcaacatggg gcttagctat cttcatggtg gtaatgagca ttgctactgc
     2941 ttatgtagtt cctcgctctg ctgttgctaa agacgcagtg ttggaacagg cacagaaaga
     3001 acaacagact aacccgtata acttacccgc aggtacggct gcgccgcaaa ctgaagctcc
     3061 tgctaccaat gcacctgcta cagaaactcc ggcaccggct gctgaaactc ctgctcctgc
     3121 agcagagtaa ttcactctgt cgtcaggtaa gactttgggg taaaaccatt aatgggaagg
     3181 tgcagacgaa tgctgcattt ctttgatatt taagtgcgga ttacgcagat tacacggatt
     3241 ttcaatcttc cgcgtggtca gtgtaatccg cacttaactt tttcttgtaa aaacaatctc
     3301 tttttgatag aaacaaacga gatttaacta cctttgttgg tcgtatgaag attattaact
     3361 actattttta aatataacaa tgacagaaca tttgaaacag aaattgaatg actccgccgt
     3421 actccgatgg agtgttctag cattagtcgc atttactatg ctatgcggct atttcctcac
     3481 cgacgtaatg tctcctctaa aacccatgct tgagaaagaa ctactatggg acagtctgga
     3541 ttatggtttc ttcacaagcg cttacgggtg gtttaatgta ttcctgttga tgctgatctt
     3601 cggtggtatc attttggata agatgggagt tcgtttcacc ggaatggggg cttgcttatt
     3661 gatggtgttt ggttgtggat tgaaatacta tgcgatttct actacttttc cggaaggtgc
     3721 catgctcttc ggattcaaaa cacaggtaac cctggctgca ttggggtatg ctatcttcgg
     3781 tgtaggtgtg gaaattgccg gtatcacagt ttccaagatt atcgtaaaat ggttcaaggg
     3841 taaggaaatg gcattggcta tgggacttga aatggctacg gcacgtatcg gaacaactct
     3901 ggcaatggtg cttacggttc ctttggccga ctttttcgga tctacggatg agagtggcac
     3961 attccatacc aatattcctg ctcctattct gttttgtctg attatgttgt gcgtgggtac
     4021 gattgctttc ttcctttata ctttctatga taagaagttg gatgcttctt tggatgcaga
     4081 gggattggag ccggaagagc cgttccgtat gaaagatatt gtgtatatca ttaccaataa
     4141 aggattctgg ttgattgcat tactatgtgt attgttctac tcggctgtat tcccctttat
     4201 caagtatgct gccgacttga tggtgcagaa gtataatgta gatccgaagt tggcgggaac
     4261 gattcccgga ttgttgccga ttggtgcgat tatcctgact ccgttgttcg gctcgcttta
     4321 tgaccgtatc ggtaagggag ctacgttgat gataatcgga tcagtgatgc ttatttttgt
     4381 gcatacgatg ttcgctctgc ctatactgaa tatatggtgg tttgctacta tcatcatgat
     4441 tatattggga tttgccttct cgttggtgcc ttcagctatg tggccgtctg ttccgaagat
     4501 tattccggaa aaacagttgg gtaccgcata cgcattgatt ttctgggtac agaactgggg
     4561 attgatgggt gttcctttgt tgatcggatg ggtgttgaat acttattgta aaggtccggt
     4621 agtagacggt gcacagactt atgactacac gttgccgatg gctatttttg ctctctttgg
     4681 tgtgcttgct ctgattgtgg ctttgatgtt gaaggcagag aacaagaaga agggatacgg
     4741 tctggaagag gcgaatatcc aaaagtaact aggaaattca atacctaaag taacaaagga
     4801 attttgtatc aaggtgtaaa caaaagggta tcagtatgaa tactctgaaa taaaaaataa
     4861 gaagtatggc tgccaaagag aaaatcaacc tgttagaggt cattccctgt cgcagtgaac
     4921 atattacagc agaaagggaa ggggagacaa ttgtgctctc ctttccccgt tttaaatatc
     4981 cgtggatgca acgcttcctt gtgccgaaag gaatgtcgaa agaacttcat gtgaaattgg
     5041 aagaacacgg tacggctgta tgggaactga tagatggaaa acgcaatgtt cgtgagatta
     5101 tagaaaaact cgcagaccac tttcaaaatg aagagggcta cgagtcgcgt gtatcggctt
     5161 atctttctca aatgcagaaa gatggattta taaaactggt gataccagtc gcataaatag
     5221 gaacttatta ttatttattt gataaataca gcccaaagta tgacggcaat tgctatcagg
     5281 acccccatga taataagcgt tccccaaaca aaataattgc tgtctttctc tttctttttc
     5341 tccgagtcgt ggatgatacg ttccatttct tcgggagtgg tgttgggtag tggataaggt
     5401 tcgtttgcac ggtttagatg cttcaactta tcgttagcac gttcacgacg taggcgggaa
     5461 gcttcccgtc cctcttttat tcggcgtatc atgtcgaatg catgtccttc accaaccata
     5521 ttctttgttt tttagaagtt cacttccttg tttttctatt tcccttcttc tctgtccact
     5581 ttgagcaatc ctcccgtatt cggatcaaaa taaactttga tggtagaatt cttattgaac
     5641 aaaaccggag ccagatattc tatcacaccg aattgagtaa taggaagctc accttcgtaa
     5701 agtttctttt taccgtcggt cagtgtaacc atagcttgtc cgggtacgtt gtaggcgatt
     5761 ccatccaaat ctttcttctt cttaccgtct tcctgtggca tcttgacaga tttcaggtct
     5821 ttcagactga tataaaacgg agttcctgcc aaatcattgt tggcaactac acctaacttc
     5881 ttcgagaagc ggaaagcaac ttcattgttg aattccttgt caggggtaag gcggacagtg
     5941 aatgttcttt cttctttgtt gcaggtgccg gagaacattt gcgtcatggc ttcttcctgt
     6001 gcattcagat tgtcgagcat aatcttaagc tgtgctccgt ctgaaggcat attgtcagcc
     6061 tgtccgcgca ataaggcatt tttgctttcg cggatgttat agatttcttt agccaccagc
     6121 tcggccatct tggcggtaga gctagccatc agaatctcct cggtcaggaa ttcgcgagga
     6181 ttcgctttct tttggaggac tgcgggagcg ggagcaactt ttttgcctac actgctattg
     6241 ctgtaaggaa cattgatcgt tttcacaatg ccatcctctg tcagttccat aagcggtgct
     6301 actgtcttat ccttcaattt tacgaaatac gtagtttcgc tgttgggcac acctacggat
     6361 ttcactttta cgctagccag ttcccagtac tcttcaggat cggcggagac gttggtcagt
     6421 cgcaggtaac gatcagcata tttgctgaat tctcccggag tatagttgac tttgttggct
     6481 tttatttcaa gttctatttg ggttttggga agactgtaaa ccactccata gtcttttcct
     6541 cgggtaaccc ctgtcagtac ttcggtttgt gcataggcgg acgttgtcat aagtagtcct
     6601 gctgctataa ttaacttttt catattcggt tcttttttaa ctggttttga aaacaaagtt
     6661 aatgaagtta ttgaaaaaac tgtaagttct taacttttat tcgcttacaa gtcgccatgc
     6721 tgtcggcaga caggtgataa tatcgcttgc gatcattccg atcattcctt gcttcttttg
     6781 agcgacatcg cccgccaatc cgtgaatgta agtgccgatt ttagcggctt cttcggtggg
     6841 ataaccttgg gcaagcagtg ccaggattac tccggtcagt acgtcaccgc tacctccggt
     6901 tgccattccc ggatttccgg ttgggttgaa gaaacattta ccttctgggg tgataatggc
     6961 ggaataggct ccttttaaaa taatgtgaac atgggcggca cgagccaatt cgcaagcctt
     7021 catcagacgt tcgtaagagt cttggcattt gccggtcaga cgttccagtt ctttcggatg
     7081 cggggtgagg atggaaccct tcggcaggtg ggtaagggta tggcggtggt tggcaaggat
     7141 attaagtgcg tcggcatcca ctacaacagg agtctggcaa tgttccagtt gctccaataa
     7201 ggcagcttcc gtttcctcgt ttcgtcccag tcccggaccg atgccgactg cttgatagtc
     7261 gtccgtgtcg gtaggtacgg caaaacaggt ttcgttgatg tcggtttcta cgattgcttc
     7321 gggtatggag gtctgcaaga tgtcgttgtt gcacattggt gcatgaacag tcagcaaccc
     7381 tactcccgaa cggaggcagg cacgggcagc gagaacagag gctcctgcca ttccttttga
     7441 accggcaatc aatagtgcat gaccgaagtt tcccttgtgg gcaaactgtt tgcgtggctt
     7501 gatgagtgaa cggatttgct ctatttccaa catttcgtag ttcgtttcca tctcttcaat
     7561 accgtcttcg ctcaattgga tatccaacaa ttcccattct ccgacaaatt ctgtgttttc
     7621 tgcgaaaaga aaggcgagct tcggcagttg cagactgaaa gttacgtcgg cacggataat
     7681 attagctttt acgttgaatg tattttcttc tcccatcagt ccggaaggga tgtcgatggc
     7741 tactaccatg gcaggggagg aattgatgta tttcactacg gcagcgaatc cgccgctcaa
     7801 cggtttgttc aggcctgaac cgaataatcc gtcgattacc agatggtcgg gcgtcagggc
     7861 gggaggtacg aattgggtac tgatctcgtg gaattttact tcttccatca tttctaccag
     7921 ttctttattg gtctggcagt cgggtgaaag ttctcctttc gtgttgaaga gaaatacctc
     7981 gattttatat cctttttcag ccatcatgcg ggctacggcg agagcgtctc cgccattatt
     8041 ccccggtccg gcaaagatag tgaccggcgt ttccgtattc catctgtctg tgatggcttt
     8101 tgttaatacg gttgctgcac gttccatcag atcgattgat gcaataggtt cgttctcaat
     8161 ggtataagcg tccaatttct tgatactgct gcttggaaat attttcattg cgatgttctt
     8221 ttagttttcg gattacaaat gtacatgatt cttctgactt ttcccgtttg ttgtgggaag
     8281 aaaaccataa ttgcaacttt taattcatca ttagttctat ctttgggtca gagaaatatc
     8341 tgcttttgaa ctattaagtg ttagaataac tccgccaaaa aataattcaa tgcagcacca
     8401 ttatgaactt acttttattt ctcctgaaaa agatttctgg ttcttcgtca aatttggtgg
     8461 taaattcttt atctctttat ttccaagtta ataattatcc ctttttactc actttcataa
     8521 gaaaatatag gcactgactg aattagctaa atgagcggag aaaaacttac caccaaattt
     8581 gacgaagaac cagatttctt catttcattt ctcatattct cattgttttt cgataaacga
     8641 aagctaatca aatagatatc ttatgagaaa cactttttcg aaacggtatt tctcataagt
     8701 tctcccatat tttggctcaa aagccgcctt attctcatag tatttcaggg tatttctcat
     8761 agtcaaaagc catttgttct tccttttttc tttcagcctg ccttattttt atcaggaaat
     8821 gaagctacta tttagataaa atagtggctt tttgcttgaa gatgctcatt ggtctcgatt
     8881 gtcccatata ttgtgggaaa gttttccttc aatatacggg aatactttcc cacaaaataa
     8941 gggaatactt tcccaagcct tagggaatct tttcccacaa tatgtggaac taagacactg
     9001 tgtatggaag caagcaaaag gaatacatag ttttatttat tcaatgtcag cttccggcac
     9061 actacactat gagaaatgaa gcaaaatccg ggttattttg cgaagaaact atgagaaata
     9121 cctgttttaa aatcatttct catagcctat cttattagtt tactgccact tgtttcttat
     9181 ttatgagaat atgagaaatg aaaaatcttt ttctgtagag gcgcggatgg aaattgtgtt
     9241 tagtttatcg ccataccttc ttaaacaaat ttttaatgcg gttcccctta ttaagccttt
     9301 gattatttgc cgtttccgat aaaaatgtta tctttggaga tagataatgt gcatcacatc
     9361 attttccagt gctcacaatg aaaatgaatt aaaatctaaa taacggattg tttaatcttc
     9421 taaagtttgc atgatggaaa agacaaaaat tggcttgaat gccgggaaag tatggcgcat
     9481 cttaaatgaa aaaggtgaac tttcaatgtt cgatttgtgc cgtgaattaa gtttgacgtt
     9541 tgaagacgta gctctcgcta ttggttggct ggcccgagaa gacaaaatct ttttgaggaa
     9601 aagagaagga atgctttttg ccagtatcga aaatgtcgaa tttacttttg gctaaggtgg
     9661 tagctaacct acatttaaga tggatctcca ctttattatt tacactgcta aaaaagtaat
     9721 gaagtggatc agtaggattt tttatgctcg tttttactat tccccctatt attctgtttg
     9781 ataagagaag catctaatct actttttctg tacctttgca ccccataaac tactaaacac
     9841 ataaattcat gagtgcattg aaagggcatc cgaaaggcct ttatttgatt ttcgcgacaa
     9901 gcacggcaga acgtttcagt tattacggta tgcgtgcgat ctttattctt ttcctgacgc
     9961 aggcattatt gtttgacaaa gaagcggcag catccatcta cggcagctat accggactag
    10021 tttatttaac cccgttgatt ggcggataca ttgccgataa atattgggga atccgtcgtt
    10081 ccgtgttttg gggagcggtg atgatggcag tcggacaatt cctgatgttt atgagtgcct
    10141 ccactttaga taatacaaac cttgcccact ggatgatgta tggcggacta ggcttcctga
    10201 tcttgggcaa tggttgcttc aaacccactg tctcttctct ggtaggtcag ctctacgaac
    10261 ccggagacag gcggttggat gctgcataca ccatttttta tatgggagtg aatgtaggct
    10321 cttttgctgc tcctttgatt tgtggttatc tgggtgatac cggtgatccg catgacttta
    10381 aatggggatt tcttgcagcc ggaatcatga cactgttcac cgttgttctt ttcgagactc
    10441 aaaagaataa atatcttttt tctccttccg gagaaccgat tggtattatc cccgatgcta
    10501 aacgtgaaaa gaaagaagac aaggccgacc atatctcaca cccgaagatg gacaaacgta
    10561 ccaaagtacg taataccctt gtaatcacaa ttcttaccat tgctttaata gccttcttta
    10621 actatgcatt tgaaggcgat tgggtgagta tcggcatttt taccgcctgc attgttttcc
    10681 ctgttctgat cttgttagac ggttcattga ccaaaataga acgcagccgt attttcgtta
    10741 tctatatagt agccttcttt gtcatcttct tctgggcagc ctacgaacag gcgggagctt
    10801 ctttaactct ctttgcgtcc gaacagacga atcgtgacat tttcggttgg gaaatgccgg
    10861 cttcatggtt tcaatccttc aatcccctgt ttgtagttgt cctggcatat atcatgccgg
    10921 gtgtatgggg tttcctgaac aagcgaaaga tggaacctgc ttctcctacc aaacaagcga
    10981 ttggtctgtt actcctttct ttaggttatc ttttcatctg tttcggagtg aaagatgctg
    11041 ttcccggagt gaaagtgagc atgatttggc tgacaggact ttactttatt cataccatgg
    11101 gtgaaatagc tttgtcgcct atcggacttt caatggtaaa taaattgagt ccgctgcgtt
    11161 tcgcctccct gatgatggga atctggtatc tgtctactgc cacagccaat aaatttgcgg
    11221 gaatgttgag cgggctctat ccggaagccg gaaaagtgaa gtcaatcttt ggttatcaga
    11281 ttgctaccat gtatgatttc tttatggtat tcgtcgtaat gtccggtgtt gcttcgttga
    11341 ttctgttcct tctctcgaag aaattacaga agatgatgca cggggtagaa taaaaaatcg
    11401 tatttttgca aggttatttt taaattaccg gttatggata ccattcagat aaaagacaaa
    11461 ttgtttaccg tttccattaa ggaacaagaa attcagaaag aagtgattcg cgtagcgaac
    11521 gaaatcaacc gcgatttggc aggtaagaat ccgcttttcc ttagtgtgtt gaacggttcg
    11581 ttcatgttta ccgctgattt attgaagcat atcaccatcc cttgtgaaat ctcatttgtg
    11641 aagttggcgt cttatcaggg catcacttcc accggagtga ttaaagaggt aatcggcctg
    11701 aatgaagaca ttgccggacg taccattgtg atcgtagaag atatcgtaga cacaggactg
    11761 acgatgcagc gactgctcga aacattaggt acacgcaatc ccgaagctat tcatatcgct
    11821 tctctgttgg tgaaacctga aaagctcaag gtaaacctca acattgaata tgtagcgatg
    11881 gaaatcccga acgactttat cgtaggttac ggactggatt atgatggttt cggacgtaat
    11941 tatcccgata tttatacagt agtagattaa tattaaatag gtaccagttt aaatggtaaa
    12001 tagtaaatcg ttaaattgta aataacaaaa tgttgaacat cgtaattttc ggtgctccgg
    12061 gttcaggaaa aggaacacag agcgaacgta tcgtagaaaa gtatggaatc aatcacatct
    12121 cgacaggaga tgtattgcgt gctgaaatca agaatggcac agaactgggt aaaacagcta
    12181 aaggttacat cgaccaaggt caattgattc ctgatgaatt aatgattgat attctggcaa
    12241 gcgtattcga cagcttcaaa gatagcaaag gtgtaatttt cgacggtttc ccaagaacaa
    12301 ttgcacaagc agaagcatta aagaaaatgt tggcagaaag aggacaggac gtttctgtaa
    12361 tggttgactt ggatgttccg gaagaagaac tgatggtacg tctcattaaa cgtggcaagg
    12421 attccggtcg tgctgatgat aacgaagaga caatcaagaa acgtctgcat gtatatcatt
    12481 cacagactgc tccactgatc gactggtaca agaacgaaaa gaaataccaa cacatcaacg
    12541 gcttgggtac tatggaaggt atcttcgctg aaatctgcga agcaatagat aaattgtaat
    12601 aatacaatat tataaataaa taagtcagta gccggagtgt tctaattaac tgctctaact
    12661 actgactact ttaactcttt aaaaaaatat ggctgaatcg aattttgttg attacgtaaa
    12721 gatatactgt cgctcgggta agggcggaag aggctctacg cacatgaggc gcgagaaata
    12781 ttgtcctaac ggaggtcctg atgggggcga tggtggaaga ggaggtcata tcatcttgcg
    12841 cggtaaccgt aattactgga cattgctgca cttgaagtat gaccgtcatg caatggccgg
    12901 tcatggtgaa tcggggagca aaggacgtag tttcggaaaa gacggtgcgg ataaaataat
    12961 agaagtaccc tgcggaacgg tagtttataa tgccgagaca ggggagtatc tttgtgacgt
    13021 aacagaagac ggacaggaag tggtcttgct caaaggcggc cgcggcggtc agggtaactg
    13081 gcatttcaag acggccaccc gtcaggctcc gcgttttgcg cagccaggag aaccgatgca
    13141 ggaaatgacc gttatcatgg agctgaaact gcttgccgat gttggtctgg taggtttccc
    13201 gaatgcggga aagtcaactt tgctttcttc catttcggct gccaaaccga aaattgccga
    13261 ttacccgttt actacactcg aacccaactt gggcatcgtt tcctatcacg gtggaaaatc
    13321 ctttgtgatg gcggacatac cgggtattat cgaaggtgct agccagggga aaggtttggg
    13381 actgcgtttc ttgcgtcata tcgagcgtaa ttcattactg ctgtttatgg ttccggcaga
    13441 cagcgacgac attcgtaaag aatatgaagt cttgctgaac gaactgcgta ccttcaatcc
    13501 tgaaatgttg gacaagcaac gtgtgttggc tgtcaccaag agtgatatgc tcgatcagga
    13561 gttgatggac gagattgaac ctacattgcc ggaaggcatt ccacatgtat tcatatcttc
    13621 tgtttccggt ttgggtatct cggtgttgaa agacatcctt tgggaagaac tgaacaagga
    13681 aagcaataaa atagaggaca tcgttcaccg tccgaaagac gtgacccgtc tgcaacagga
    13741 actcaaagac atgggcgaag atgaagacat cgtttatgaa tatgaggaag atggcgacga
    13801 tgatatcgat tatgagtacg aagaagattg ggaagaagaa tgatttctct tacaaaacat
    13861 aacgagttga agggatataa gtcattagat gcatatcccg aagtagctca tttcgtaact
    13921 acacgtcacg gaggtataag caccggagct tacggctctt tcaactgttc gccttatacc
    13981 aacgactcat gtgtgaacgt caatcgcaat cagaactggt tgtttcagtg catgaatcat
    14041 cagataaagg aattatttat tcctgaacag agtcatggtt gcgccagtct gattatcaat
    14101 gaatcatttt ttaaagaatc attggaaagg agacggctac ttctgcgagg aatggatgct
    14161 ttgataacga atgtgccggg atattgcgtt tgtgtcacga cagcggattg tgttcctgta
    14221 ttgctgtacg acaaaaaaca acacgttgtg gctgccgttc atgccggatg gaagggaacg
    14281 gtgaagcata ttgtcagtca tgtgatggac aacatgactc aaaagttcgg gacgcaaggc
    14341 gaagatgtaa tagcttgcat cgggccgagc atttcgctcg aatcatttga agtaggcgat
    14401 gaagtgtatg atgcttttga agaaagcggt ttcgatatgt ctcttatttc tatgaagaag
    14461 aaggagacag gcaaatatca tattgatttg tgggaagcca accggattga attactgaat
    14521 cgcagagtgc ctgcagagca gatagaagtg gctggaatct gtacctatat tcatcatgat
    14581 gaattcttct ccgcacgtag actgggaata gattccggtc gtacattgtc gggaataatg
    14641 attagaaagt aataattggt gtccgttatt gcaggacgct gatgattggt ttatgataag
    14701 ttatgtttga aataaaagta tctaaagaaa taaaagacgc atgtccggtt tttgccggag
    14761 ccgctgtgta tgctgttgtg aaaaatacag cttacagcga agggctttgg caggaaatcg
    14821 acgcttttac caagcaactg acttccacaa cacagatgga agacatcaaa catcaacccg
    14881 ttatctttgc tacccgtgag gcttataaac gttgtggcaa agaccccgga cgttatcgtc
    14941 cgtcagccga agctctacgc cgccgcctga tgcgtggaat tcctttatat cagattgata
    15001 cgttggtaga ccttattaat ttagtgtctc ttcgtacggg acattcgatc ggtggttttg
    15061 acgcggacaa aatacaaggt acgcaccttg aactcggtat cggcaaagca ggagaaccgt
    15121 ttgaaggtat cggacgcggt gtattgaata tcgaaggatt acctgtatat cgcgattctt
    15181 tcggaggaat cggaaccccg acaagcgatc atgaac
//
