LOCUS       gnlProkkaJEOKJBPC_11   15219 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JEOKJBPC_11.
ACCESSION   gnlProkkaJEOKJBPC_11
VERSION     gnlProkkaJEOKJBPC_11
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:07:58
            Original ID  :: gnl|Prokka|JEOKJBPC_11
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 111622
            Orig. end    :: 126841
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15219
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10351]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10351
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15219
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15219
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             complement(565..1377)
                     /locus_tag="ctg11_78"
                     /transl_table=11
                     /translation="MISLTKHNELKGYKSLDAYPEVAHFVTTRHGGISTGAYGSFNCSP
                     YTNDSCVNVNRNQNWLFQCMNHQIKELFIPEQSHGCASLIINESFFKESLERRRLLLRG
                     MDALITNVPGYCVCVTTADCVPVLLYDKKQHVVAAVHAGWKGTVKHIVSHVMDNMTQKF
                     GTQGEDVIACIGPSISLESFEVGDEVYDAFEESGFDMSLISMKKKETGKYHIDLWEANR
                     IELLNRRVPAEQIEVAGICTYIHHDEFFSARRLGIDSGRTLSGIMIRK"
     CDS             complement(1374..2528)
                     /locus_tag="ctg11_79"
                     /transl_table=11
                     /translation="MAESNFVDYVKIYCRSGKGGRGSTHMRREKYCPNGGPDGGDGGRG
                     GHIILRGNRNYWTLLHLKYDRHAMAGHGESGSKGRSFGKDGADKIIEVPCGTVVYNAET
                     GEYLCDVTEDGQEVVLLKGGRGGQGNWHFKTATRQAPRFAQPGEPMQEMTVIMELKLLA
                     DVGLVGFPNAGKSTLLSSISAAKPKIADYPFTTLEPNLGIVSYHGGKSFVMADIPGIIE
                     GASQGKGLGLRFLRHIERNSLLLFMVPADSDDIRKEYEVLLNELRTFNPEMLDKQRVLA
                     VTKSDMLDQELMDEIEPTLPEGIPHVFISSVSGLGISVLKDILWEELNKESNKIEDIVH
                     RPKDVTRLQQELKDMGEDEDIVYEYEEDGDDDIDYEYEEDWEEE"
     CDS             complement(2618..3187)
                     /locus_tag="ctg11_80"
                     /transl_table=11
                     /translation="MLNIVIFGAPGSGKGTQSERIVEKYGINHISTGDVLRAEIKNGTE
                     LGKTAKGYIDQGQLIPDELMIDILASVFDSFKDSKGVIFDGFPRTIAQAEALKKMLAER
                     GQDVSVMVDLDVPEEELMVRLIKRGKDSGRADDNEETIKKRLHVYHSQTAPLIDWYKNE
                     KKYQHINGLGTMEGIFAEICEAIDKL"
     CDS             complement(3247..3783)
                     /locus_tag="ctg11_81"
                     /transl_table=11
                     /translation="MDTIQIKDKLFTVSIKEQEIQKEVIRVANEINRDLAGKNPLFLSV
                     LNGSFMFTADLLKHITIPCEISFVKLASYQGITSTGVIKEVIGLNEDIAGRTIVIVEDI
                     VDTGLTMQRLLETLGTRNPEAIHIASLLVKPEKLKVNLNIEYVAMEIPNDFIVGYGLDY
                     DGFGRNYPDIYTVVD"
     CDS             complement(3824..5368)
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 46.8; E-value: 2.5e-14)"
                     /gene_kind="transport"
                     /locus_tag="ctg11_82"
                     /transl_table=11
                     /translation="MSALKGHPKGLYLIFATSTAERFSYYGMRAIFILFLTQALLFDKE
                     AAASIYGSYTGLVYLTPLIGGYIADKYWGIRRSVFWGAVMMAVGQFLMFMSASTLDNTN
                     LAHWMMYGGLGFLILGNGCFKPTVSSLVGQLYEPGDRRLDAAYTIFYMGVNVGSFAAPL
                     ICGYLGDTGDPHDFKWGFLAAGIMTLFTVVLFETQKNKYLFSPSGEPIGIIPDAKREKK
                     EDKADHISHPKMDKRTKVRNTLVITILTIALIAFFNYAFEGDWVSIGIFTACIVFPVLI
                     LLDGSLTKIERSRIFVIYIVAFFVIFFWAAYEQAGASLTLFASEQTNRDIFGWEMPASW
                     FQSFNPLFVVVLAYIMPGVWGFLNKRKMEPASPTKQAIGLLLLSLGYLFICFGVKDAVP
                     GVKVSMIWLTGLYFIHTMGEIALSPIGLSMVNKLSPLRFASLMMGIWYLSTATANKFAG
                     MLSGLYPEAGKVKSIFGYQIATMYDFFMVFVVMSGVASLILFLLSKKLQKMMHGVE"
     CDS             complement(5562..5786)
                     /locus_tag="ctg11_83"
                     /transl_table=11
                     /translation="MMEKTKIGLNAGKVWRILNEKGELSMFDLCRELSLTFEDVALAIG
                     WLAREDKIFLRKREGMLFASIENVEFTFG"
     CDS             6457..6573
                     /locus_tag="ctg11_84"
                     /transl_table=11
                     /translation="MRNTLKYYENKAAFEPKYGRTYEKYRFEKVFLIRYLFD"
     CDS             7009..8520
                     /locus_tag="ctg11_85"
                     /transl_table=11
                     /translation="MKIFPSSSIKKLDAYTIENEPIASIDLMERAATVLTKAITDRWNT
                     ETPVTIFAGPGNNGGDALAVARMMAEKGYKIEVFLFNTKGELSPDCQTNKELVEMMEEV
                     KFHEISTQFVPPALTPDHLVIDGLFGSGLNKPLSGGFAAVVKYINSSPAMVVAIDIPSG
                     LMGEENTFNVKANIIRADVTFSLQLPKLAFLFAENTEFVGEWELLDIQLSEDGIEEMET
                     NYEMLEIEQIRSLIKPRKQFAHKGNFGHALLIAGSKGMAGASVLAARACLRSGVGLLTV
                     HAPMCNNDILQTSIPEAIVETDINETCFAVPTDTDDYQAVGIGPGLGRNEETEAALLEQ
                     LEHCQTPVVVDADALNILANHRHTLTHLPKGSILTPHPKELERLTGKCQDSYERLMKAC
                     ELARAAHVHIILKGAYSAIITPEGKCFFNPTGNPGMATGGSGDVLTGVILALLAQGYPT
                     EEAAKIGTYIHGLAGDVAQKKQGMIGMIASDIITCLPTAWRLVSE"
     CDS             8594..9661
                     /locus_tag="ctg11_86"
                     /transl_table=11
                     /translation="MKKLIIAAGLLMTTSAYAQTEVLTGVTRGKDYGVVYSLPKTQIEL
                     EIKANKVNYTPGEFSKYADRYLRLTNVSADPEEYWELASVKVKSVGVPNSETTYFVKLK
                     DKTVAPLMELTEDGIVKTINVPYSNSSVGKKVAPAPAVLQKKANPREFLTEEILMASST
                     AKMAELVAKEIYNIRESKNALLRGQADNMPSDGAQLKIMLDNLNAQEEAMTQMFSGTCN
                     KEERTFTVRLTPDKEFNNEVAFRFSKKLGVVANNDLAGTPFYISLKDLKSVKMPQEDGK
                     KKKDLDGIAYNVPGQAMVTLTDGKKKLYEGELPITQFGVIEYLAPVLFNKNSTIKVYFD
                     PNTGGLLKVDREEGK"
     CDS             9698..9982
                     /locus_tag="ctg11_87"
                     /transl_table=11
                     /translation="MVGEGHAFDMIRRIKEGREASRLRRERANDKLKHLNRANEPYPLP
                     NTTPEEMERIIHDSEKKKEKDSNYFVWGTLIIMGVLIAIAVILWAVFIK"
     CDS             complement(10001..10351)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg11_88"
                     /sec_met_domain="PqqD_RRE (E-value: 7.1e-11, bitscore:
                     34.4, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.6e-17, bitscore: 55.6,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAKEKINLLEVIPCRSEHITAEREGETIVLSFPRFKYPWMQRFL
                     VPKGMSKELHVKLEEHGTAVWELIDGKRNVREIIEKLADHFQNEEGYESRVSAYLSQMQ
                     KDGFIKLVIPVA"
     CDS             complement(10449..11837)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 92.3; E-value: 4e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg11_89"
                     /transl_table=11
                     /translation="MTEHLKQKLNDSAVLRWSVLALVAFTMLCGYFLTDVMSPLKPMLE
                     KELLWDSLDYGFFTSAYGWFNVFLLMLIFGGIILDKMGVRFTGMGACLLMVFGCGLKYY
                     AISTTFPEGAMLFGFKTQVTLAALGYAIFGVGVEIAGITVSKIIVKWFKGKEMALAMGL
                     EMATARIGTTLAMVLTVPLADFFGSTDESGTFHTNIPAPILFCLIMLCVGTIAFFLYTF
                     YDKKLDASLDAEGLEPEEPFRMKDIVYIITNKGFWLIALLCVLFYSAVFPFIKYAADLM
                     VQKYNVDPKLAGTIPGLLPIGAIILTPLFGSLYDRIGKGATLMIIGSVMLIFVHTMFAL
                     PILNIWWFATIIMIILGFAFSLVPSAMWPSVPKIIPEKQLGTAYALIFWVQNWGLMGVP
                     LLIGWVLNTYCKGPVVDGAQTYDYTLPMAIFALFGVLALIVALMLKAENKKKGYGLEEA
                     NIQK"
     CDS             complement(12087..12482)
                     /locus_tag="ctg11_90"
                     /transl_table=11
                     /translation="MYLLFVILMVIAALLMCFIVLIQNSKGGGLASGFSSSNAIMGVRK
                     TTDFLEKATWGLAIFMVVMSIATAYVVPRSAVAKDAVLEQAQKEQQTNPYNLPAGTAAP
                     QTEAPATNAPATETPAPAAETPAPAAE"
     CDS             complement(12489..13262)
                     /locus_tag="ctg11_91"
                     /transl_table=11
                     /translation="MTSVNFQQWIQHPETLNRDTLYELRNLLARYPYFQSLRLLYLKNL
                     YILHDISFGGELRKAVLYIADRRQLFRLIEGDRYDVQARKKGVPLTEVLKDEPSVDRTL
                     ALIDAFLSTAPEEVTARTSFDYSMDYTSYLLEETPATEQPAEETPKLKGYELIDDFIEK
                     SESDSPLCMKPLREEMPSSPTSSDELTEEETMKEEEEDDSCFTETLAKIYVKQQRYSKA
                     LEIIKKLSLKYPKKNAYFADQIRFLEKLIINANSK"
     CDS             complement(13268..13795)
                     /locus_tag="ctg11_92"
                     /transl_table=11
                     /translation="MNWIKKIIRPLLLFGLPLVVIACTVSYKFNGSSINYDKVKTISIA
                     DFPIKSEYVYAPLATKFNEDLKDIFIRQTRLQLLKPNQNADLQIDGEITGYNQYNQAVS
                     ADGYSSETKLTITVNVRFVNNTNHAEDFEQQFSAFRTYDSSQLLTAVQDGLIAEMSKEI
                     TDQIFNATVANW"
     CDS             complement(13782..15023)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 390.2; E-value:
                     2.3e-118)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg11_93"
                     /transl_table=11
                     /translation="MTKAEIQQVKQRFGIIGNTEALSRAIDVAIQVAPTDLSVLITGES
                     GVGKESFPQIIHQYSRRKHGQYIAVNCGAIPEGTIDSELFGHEKGAFTGAIGERKGYFG
                     EADGGTIFLDEVGELPMSTQARLLRVLESGEFMKVGSSKVQKTDVRVVAATNVNLTQAI
                     AEGRFREDLYYRLNTVPIQIPPLRERGDDVLLLFRKFSADFAEKYRMPAIQLTEDAKKE
                     LLAYPWPGNVRQLKNITEQISIIETNREISAAILQNYLPAQNTQRLPALMGTRESKGFE
                     SEREILYSVLFDMRQEVAELKKMVHNLMAERAGQVGQVGQMGTVVTTPVVTAHQPSVPA
                     IIHTMQPTVCKDDDDIQDTEEYVEESPLSLDEVEKEMIRKALERHHGKRKSAAKDLNIS
                     ERTLYRKIKEYELD"
     CDS             complement(15033..15218)
                     /locus_tag="ctg11_94"
                     /transl_table=11
                     /translation="MDIAGKGVACEDSFRQAIYVAIDVFRNRQREKVARANPLRKQYYE
                     KRDDSDKLKLDTVDED"
ORIGIN
        1 gttcatgatc gcttgtcggg gttccgattc ctccgaaaga atcgcgatat acaggtaatc
       61 cttcgatatt caatacaccg cgtccgatac cttcaaacgg ttctcctgct ttgccgatac
      121 cgagttcaag gtgcgtacct tgtattttgt ccgcgtcaaa accaccgatc gaatgtcccg
      181 tacgaagaga cactaaatta ataaggtcta ccaacgtatc aatctgatat aaaggaattc
      241 cacgcatcag gcggcggcgt agagcttcgg ctgacggacg ataacgtccg gggtctttgc
      301 cacaacgttt ataagcctca cgggtagcaa agataacggg ttgatgtttg atgtcttcca
      361 tctgtgttgt ggaagtcagt tgcttggtaa aagcgtcgat ttcctgccaa agcccttcgc
      421 tgtaagctgt atttttcaca acagcataca cagcggctcc ggcaaaaacc ggacatgcgt
      481 cttttatttc tttagatact tttatttcaa acataactta tcataaacca atcatcagcg
      541 tcctgcaata acggacacca attattactt tctaatcatt attcccgaca atgtacgacc
      601 ggaatctatt cccagtctac gtgcggagaa gaattcatca tgatgaatat aggtacagat
      661 tccagccact tctatctgct ctgcaggcac tctgcgattc agtaattcaa tccggttggc
      721 ttcccacaaa tcaatatgat atttgcctgt ctccttcttc ttcatagaaa taagagacat
      781 atcgaaaccg ctttcttcaa aagcatcata cacttcatcg cctacttcaa atgattcgag
      841 cgaaatgctc ggcccgatgc aagctattac atcttcgcct tgcgtcccga acttttgagt
      901 catgttgtcc atcacatgac tgacaatatg cttcaccgtt cccttccatc cggcatgaac
      961 ggcagccaca acgtgttgtt ttttgtcgta cagcaataca ggaacacaat ccgctgtcgt
     1021 gacacaaacg caatatcccg gcacattcgt tatcaaagca tccattcctc gcagaagtag
     1081 ccgtctcctt tccaatgatt ctttaaaaaa tgattcattg ataatcagac tggcgcaacc
     1141 atgactctgt tcaggaataa ataattcctt tatctgatga ttcatgcact gaaacaacca
     1201 gttctgattg cgattgacgt tcacacatga gtcgttggta taaggcgaac agttgaaaga
     1261 gccgtaagct ccggtgctta tacctccgtg acgtgtagtt acgaaatgag ctacttcggg
     1321 atatgcatct aatgacttat atcccttcaa ctcgttatgt tttgtaagag aaatcattct
     1381 tcttcccaat cttcttcgta ctcataatcg atatcatcgt cgccatcttc ctcatattca
     1441 taaacgatgt cttcatcttc gcccatgtct ttgagttcct gttgcagacg ggtcacgtct
     1501 ttcggacggt gaacgatgtc ctctatttta ttgctttcct tgttcagttc ttcccaaagg
     1561 atgtctttca acaccgagat acccaaaccg gaaacagaag atatgaatac atgtggaatg
     1621 ccttccggca atgtaggttc aatctcgtcc atcaactcct gatcgagcat atcactcttg
     1681 gtgacagcca acacacgttg cttgtccaac atttcaggat tgaaggtacg cagttcgttc
     1741 agcaagactt catattcttt acgaatgtcg tcgctgtctg ccggaaccat aaacagcagt
     1801 aatgaattac gctcgatatg acgcaagaaa cgcagtccca aacctttccc ctggctagca
     1861 ccttcgataa tacccggtat gtccgccatc acaaaggatt ttccaccgtg ataggaaacg
     1921 atgcccaagt tgggttcgag tgtagtaaac gggtaatcgg caattttcgg tttggcagcc
     1981 gaaatggaag aaagcaaagt tgactttccc gcattcggga aacctaccag accaacatcg
     2041 gcaagcagtt tcagctccat gataacggtc atttcctgca tcggttctcc tggctgcgca
     2101 aaacgcggag cctgacgggt ggccgtcttg aaatgccagt taccctgacc gccgcggccg
     2161 cctttgagca agaccacttc ctgtccgtct tctgttacgt cacaaagata ctcccctgtc
     2221 tcggcattat aaactaccgt tccgcagggt acttctatta ttttatccgc accgtctttt
     2281 ccgaaactac gtcctttgct ccccgattca ccatgaccgg ccattgcatg acggtcatac
     2341 ttcaagtgca gcaatgtcca gtaattacgg ttaccgcgca agatgatatg acctcctctt
     2401 ccaccatcgc ccccatcagg acctccgtta ggacaatatt tctcgcgcct catgtgcgta
     2461 gagcctcttc cgcccttacc cgagcgacag tatatcttta cgtaatcaac aaaattcgat
     2521 tcagccatat ttttttaaag agttaaagta gtcagtagtt agagcagtta attagaacac
     2581 tccggctact gacttattta tttataatat tgtattatta caatttatct attgcttcgc
     2641 agatttcagc gaagatacct tccatagtac ccaagccgtt gatgtgttgg tatttctttt
     2701 cgttcttgta ccagtcgatc agtggagcag tctgtgaatg atatacatgc agacgtttct
     2761 tgattgtctc ttcgttatca tcagcacgac cggaatcctt gccacgttta atgagacgta
     2821 ccatcagttc ttcttccgga acatccaagt caaccattac agaaacgtcc tgtcctcttt
     2881 ctgccaacat tttctttaat gcttctgctt gtgcaattgt tcttgggaaa ccgtcgaaaa
     2941 ttacaccttt gctatctttg aagctgtcga atacgcttgc cagaatatca atcattaatt
     3001 catcaggaat caattgacct tggtcgatgt aacctttagc tgttttaccc agttctgtgc
     3061 cattcttgat ttcagcacgc aatacatctc ctgtcgagat gtgattgatt ccatactttt
     3121 ctacgatacg ttcgctctgt gttccttttc ctgaacccgg agcaccgaaa attacgatgt
     3181 tcaacatttt gttatttaca atttaacgat ttactattta ccatttaaac tggtacctat
     3241 ttaatattaa tctactactg tataaatatc gggataatta cgtccgaaac catcataatc
     3301 cagtccgtaa cctacgataa agtcgttcgg gatttccatc gctacatatt caatgttgag
     3361 gtttaccttg agcttttcag gtttcaccaa cagagaagcg atatgaatag cttcgggatt
     3421 gcgtgtacct aatgtttcga gcagtcgctg catcgtcagt cctgtgtcta cgatatcttc
     3481 tacgatcaca atggtacgtc cggcaatgtc ttcattcagg ccgattacct ctttaatcac
     3541 tccggtggaa gtgatgccct gataagacgc caacttcaca aatgagattt cacaagggat
     3601 ggtgatatgc ttcaataaat cagcggtaaa catgaacgaa ccgttcaaca cactaaggaa
     3661 aagcggattc ttacctgcca aatcgcggtt gatttcgttc gctacgcgaa tcacttcttt
     3721 ctgaatttct tgttccttaa tggaaacggt aaacaatttg tcttttatct gaatggtatc
     3781 cataaccggt aatttaaaaa taaccttgca aaaatacgat tttttattct accccgtgca
     3841 tcatcttctg taatttcttc gagagaagga acagaatcaa cgaagcaaca ccggacatta
     3901 cgacgaatac cataaagaaa tcatacatgg tagcaatctg ataaccaaag attgacttca
     3961 cttttccggc ttccggatag agcccgctca acattcccgc aaatttattg gctgtggcag
     4021 tagacagata ccagattccc atcatcaggg aggcgaaacg cagcggactc aatttattta
     4081 ccattgaaag tccgataggc gacaaagcta tttcacccat ggtatgaata aagtaaagtc
     4141 ctgtcagcca aatcatgctc actttcactc cgggaacagc atctttcact ccgaaacaga
     4201 tgaaaagata acctaaagaa aggagtaaca gaccaatcgc ttgtttggta ggagaagcag
     4261 gttccatctt tcgcttgttc aggaaacccc atacacccgg catgatatat gccaggacaa
     4321 ctacaaacag gggattgaag gattgaaacc atgaagccgg catttcccaa ccgaaaatgt
     4381 cacgattcgt ctgttcggac gcaaagagag ttaaagaagc tcccgcctgt tcgtaggctg
     4441 cccagaagaa gatgacaaag aaggctacta tatagataac gaaaatacgg ctgcgttcta
     4501 ttttggtcaa tgaaccgtct aacaagatca gaacagggaa aacaatgcag gcggtaaaaa
     4561 tgccgatact cacccaatcg ccttcaaatg catagttaaa gaaggctatt aaagcaatgg
     4621 taagaattgt gattacaagg gtattacgta ctttggtacg tttgtccatc ttcgggtgtg
     4681 agatatggtc ggccttgtct tctttctttt cacgtttagc atcggggata ataccaatcg
     4741 gttctccgga aggagaaaaa agatatttat tcttttgagt ctcgaaaaga acaacggtga
     4801 acagtgtcat gattccggct gcaagaaatc cccatttaaa gtcatgcgga tcaccggtat
     4861 cacccagata accacaaatc aaaggagcag caaaagagcc tacattcact cccatataaa
     4921 aaatggtgta tgcagcatcc aaccgcctgt ctccgggttc gtagagctga cctaccagag
     4981 aagagacagt gggtttgaag caaccattgc ccaagatcag gaagcctagt ccgccataca
     5041 tcatccagtg ggcaaggttt gtattatcta aagtggaggc actcataaac atcaggaatt
     5101 gtccgactgc catcatcacc gctccccaaa acacggaacg acggattccc caatatttat
     5161 cggcaatgta tccgccaatc aacggggtta aataaactag tccggtatag ctgccgtaga
     5221 tggatgctgc cgcttctttg tcaaacaata atgcctgcgt caggaaaaga ataaagatcg
     5281 cacgcatacc gtaataactg aaacgttctg ccgtgcttgt cgcgaaaatc aaataaaggc
     5341 ctttcggatg ccctttcaat gcactcatga atttatgtgt ttagtagttt atggggtgca
     5401 aaggtacaga aaaagtagat tagatgcttc tcttatcaaa cagaataata gggggaatag
     5461 taaaaacgag cataaaaaat cctactgatc cacttcatta cttttttagc agtgtaaata
     5521 ataaagtgga gatccatctt aaatgtaggt tagctaccac cttagccaaa agtaaattcg
     5581 acattttcga tactggcaaa aagcattcct tctcttttcc tcaaaaagat tttgtcttct
     5641 cgggccagcc aaccaatagc gagagctacg tcttcaaacg tcaaacttaa ttcacggcac
     5701 aaatcgaaca ttgaaagttc acctttttca tttaagatgc gccatacttt cccggcattc
     5761 aagccaattt ttgtcttttc catcatgcaa actttagaag attaaacaat ccgttattta
     5821 gattttaatt cattttcatt gtgagcactg gaaaatgatg tgatgcacat tatctatctc
     5881 caaagataac atttttatcg gaaacggcaa ataatcaaag gcttaataag gggaaccgca
     5941 ttaaaaattt gtttaagaag gtatggcgat aaactaaaca caatttccat ccgcgcctct
     6001 acagaaaaag atttttcatt tctcatattc tcataaataa gaaacaagtg gcagtaaact
     6061 aataagatag gctatgagaa atgattttaa aacaggtatt tctcatagtt tcttcgcaaa
     6121 ataacccgga ttttgcttca tttctcatag tgtagtgtgc cggaagctga cattgaataa
     6181 ataaaactat gtattccttt tgcttgcttc catacacagt gtcttagttc cacatattgt
     6241 gggaaaagat tccctaaggc ttgggaaagt attcccttat tttgtgggaa agtattcccg
     6301 tatattgaag gaaaactttc ccacaatata tgggacaatc gagaccaatg agcatcttca
     6361 agcaaaaagc cactatttta tctaaatagt agcttcattt cctgataaaa ataaggcagg
     6421 ctgaaagaaa aaaggaagaa caaatggctt ttgactatga gaaataccct gaaatactat
     6481 gagaataagg cggcttttga gccaaaatat gggagaactt atgagaaata ccgtttcgaa
     6541 aaagtgtttc tcataagata tctatttgat tagctttcgt ttatcgaaaa acaatgagaa
     6601 tatgagaaat gaaatgaaga aatctggttc ttcgtcaaat ttggtggtaa gtttttctcc
     6661 gctcatttag ctaattcagt cagtgcctat attttcttat gaaagtgagt aaaaagggat
     6721 aattattaac ttggaaataa agagataaag aatttaccac caaatttgac gaagaaccag
     6781 aaatcttttt caggagaaat aaaagtaagt tcataatggt gctgcattga attatttttt
     6841 ggcggagtta ttctaacact taatagttca aaagcagata tttctctgac ccaaagatag
     6901 aactaatgat gaattaaaag ttgcaattat ggttttcttc ccacaacaaa cgggaaaagt
     6961 cagaagaatc atgtacattt gtaatccgaa aactaaaaga acatcgcaat gaaaatattt
     7021 ccaagcagca gtatcaagaa attggacgct tataccattg agaacgaacc tattgcatca
     7081 atcgatctga tggaacgtgc agcaaccgta ttaacaaaag ccatcacaga cagatggaat
     7141 acggaaacgc cggtcactat ctttgccgga ccggggaata atggcggaga cgctctcgcc
     7201 gtagcccgca tgatggctga aaaaggatat aaaatcgagg tatttctctt caacacgaaa
     7261 ggagaacttt cacccgactg ccagaccaat aaagaactgg tagaaatgat ggaagaagta
     7321 aaattccacg agatcagtac ccaattcgta cctcccgccc tgacgcccga ccatctggta
     7381 atcgacggat tattcggttc aggcctgaac aaaccgttga gcggcggatt cgctgccgta
     7441 gtgaaataca tcaattcctc ccctgccatg gtagtagcca tcgacatccc ttccggactg
     7501 atgggagaag aaaatacatt caacgtaaaa gctaatatta tccgtgccga cgtaactttc
     7561 agtctgcaac tgccgaagct cgcctttctt ttcgcagaaa acacagaatt tgtcggagaa
     7621 tgggaattgt tggatatcca attgagcgaa gacggtattg aagagatgga aacgaactac
     7681 gaaatgttgg aaatagagca aatccgttca ctcatcaagc cacgcaaaca gtttgcccac
     7741 aagggaaact tcggtcatgc actattgatt gccggttcaa aaggaatggc aggagcctct
     7801 gttctcgctg cccgtgcctg cctccgttcg ggagtagggt tgctgactgt tcatgcacca
     7861 atgtgcaaca acgacatctt gcagacctcc atacccgaag caatcgtaga aaccgacatc
     7921 aacgaaacct gttttgccgt acctaccgac acggacgact atcaagcagt cggcatcggt
     7981 ccgggactgg gacgaaacga ggaaacggaa gctgccttat tggagcaact ggaacattgc
     8041 cagactcctg ttgtagtgga tgccgacgca cttaatatcc ttgccaacca ccgccatacc
     8101 cttacccacc tgccgaaggg ttccatcctc accccgcatc cgaaagaact ggaacgtctg
     8161 accggcaaat gccaagactc ttacgaacgt ctgatgaagg cttgcgaatt ggctcgtgcc
     8221 gcccatgttc acattatttt aaaaggagcc tattccgcca ttatcacccc agaaggtaaa
     8281 tgtttcttca acccaaccgg aaatccggga atggcaaccg gaggtagcgg tgacgtactg
     8341 accggagtaa tcctggcact gcttgcccaa ggttatccca ccgaagaagc cgctaaaatc
     8401 ggcacttaca ttcacggatt ggcgggcgat gtcgctcaaa agaagcaagg aatgatcgga
     8461 atgatcgcaa gcgatattat cacctgtctg ccgacagcat ggcgacttgt aagcgaataa
     8521 aagttaagaa cttacagttt tttcaataac ttcattaact ttgttttcaa aaccagttaa
     8581 aaaagaaccg aatatgaaaa agttaattat agcagcagga ctacttatga caacgtccgc
     8641 ctatgcacaa accgaagtac tgacaggggt tacccgagga aaagactatg gagtggttta
     8701 cagtcttccc aaaacccaaa tagaacttga aataaaagcc aacaaagtca actatactcc
     8761 gggagaattc agcaaatatg ctgatcgtta cctgcgactg accaacgtct ccgccgatcc
     8821 tgaagagtac tgggaactgg ctagcgtaaa agtgaaatcc gtaggtgtgc ccaacagcga
     8881 aactacgtat ttcgtaaaat tgaaggataa gacagtagca ccgcttatgg aactgacaga
     8941 ggatggcatt gtgaaaacga tcaatgttcc ttacagcaat agcagtgtag gcaaaaaagt
     9001 tgctcccgct cccgcagtcc tccaaaagaa agcgaatcct cgcgaattcc tgaccgagga
     9061 gattctgatg gctagctcta ccgccaagat ggccgagctg gtggctaaag aaatctataa
     9121 catccgcgaa agcaaaaatg ccttattgcg cggacaggct gacaatatgc cttcagacgg
     9181 agcacagctt aagattatgc tcgacaatct gaatgcacag gaagaagcca tgacgcaaat
     9241 gttctccggc acctgcaaca aagaagaaag aacattcact gtccgcctta cccctgacaa
     9301 ggaattcaac aatgaagttg ctttccgctt ctcgaagaag ttaggtgtag ttgccaacaa
     9361 tgatttggca ggaactccgt tttatatcag tctgaaagac ctgaaatctg tcaagatgcc
     9421 acaggaagac ggtaagaaga agaaagattt ggatggaatc gcctacaacg tacccggaca
     9481 agctatggtt acactgaccg acggtaaaaa gaaactttac gaaggtgagc ttcctattac
     9541 tcaattcggt gtgatagaat atctggctcc ggttttgttc aataagaatt ctaccatcaa
     9601 agtttatttt gatccgaata cgggaggatt gctcaaagtg gacagagaag aagggaaata
     9661 gaaaaacaag gaagtgaact tctaaaaaac aaagaatatg gttggtgaag gacatgcatt
     9721 cgacatgata cgccgaataa aagagggacg ggaagcttcc cgcctacgtc gtgaacgtgc
     9781 taacgataag ttgaagcatc taaaccgtgc aaacgaacct tatccactac ccaacaccac
     9841 tcccgaagaa atggaacgta tcatccacga ctcggagaaa aagaaagaga aagacagcaa
     9901 ttattttgtt tggggaacgc ttattatcat gggggtcctg atagcaattg ccgtcatact
     9961 ttgggctgta tttatcaaat aaataataat aagttcctat ttatgcgact ggtatcacca
    10021 gttttataaa tccatctttc tgcatttgag aaagataagc cgatacacgc gactcgtagc
    10081 cctcttcatt ttgaaagtgg tctgcgagtt tttctataat ctcacgaaca ttgcgttttc
    10141 catctatcag ttcccataca gccgtaccgt gttcttccaa tttcacatga agttctttcg
    10201 acattccttt cggcacaagg aagcgttgca tccacggata tttaaaacgg ggaaaggaga
    10261 gcacaattgt ctccccttcc ctttctgctg taatatgttc actgcgacag ggaatgacct
    10321 ctaacaggtt gattttctct ttggcagcca tacttcttat tttttatttc agagtattca
    10381 tactgatacc cttttgttta caccttgata caaaattcct ttgttacttt aggtattgaa
    10441 tttcctagtt acttttggat attcgcctct tccagaccgt atcccttctt cttgttctct
    10501 gccttcaaca tcaaagccac aatcagagca agcacaccaa agagagcaaa aatagccatc
    10561 ggcaacgtgt agtcataagt ctgtgcaccg tctactaccg gacctttaca ataagtattc
    10621 aacacccatc cgatcaacaa aggaacaccc atcaatcccc agttctgtac ccagaaaatc
    10681 aatgcgtatg cggtacccaa ctgtttttcc ggaataatct tcggaacaga cggccacata
    10741 gctgaaggca ccaacgagaa ggcaaatccc aatataatca tgatgatagt agcaaaccac
    10801 catatattca gtataggcag agcgaacatc gtatgcacaa aaataagcat cactgatccg
    10861 attatcatca acgtagctcc cttaccgata cggtcataaa gcgagccgaa caacggagtc
    10921 aggataatcg caccaatcgg caacaatccg ggaatcgttc ccgccaactt cggatctaca
    10981 ttatacttct gcaccatcaa gtcggcagca tacttgataa aggggaatac agccgagtag
    11041 aacaatacac atagtaatgc aatcaaccag aatcctttat tggtaatgat atacacaata
    11101 tctttcatac ggaacggctc ttccggctcc aatccctctg catccaaaga agcatccaac
    11161 ttcttatcat agaaagtata aaggaagaaa gcaatcgtac ccacgcacaa cataatcaga
    11221 caaaacagaa taggagcagg aatattggta tggaatgtgc cactctcatc cgtagatccg
    11281 aaaaagtcgg ccaaaggaac cgtaagcacc attgccagag ttgttccgat acgtgccgta
    11341 gccatttcaa gtcccatagc caatgccatt tccttaccct tgaaccattt tacgataatc
    11401 ttggaaactg tgataccggc aatttccaca cctacaccga agatagcata ccccaatgca
    11461 gccagggtta cctgtgtttt gaatccgaag agcatggcac cttccggaaa agtagtagaa
    11521 atcgcatagt atttcaatcc acaaccaaac accatcaata agcaagcccc cattccggtg
    11581 aaacgaactc ccatcttatc caaaatgata ccaccgaaga tcagcatcaa caggaataca
    11641 ttaaaccacc cgtaagcgct tgtgaagaaa ccataatcca gactgtccca tagtagttct
    11701 ttctcaagca tgggttttag aggagacatt acgtcggtga ggaaatagcc gcatagcata
    11761 gtaaatgcga ctaatgctag aacactccat cggagtacgg cggagtcatt caatttctgt
    11821 ttcaaatgtt ctgtcattgt tatatttaaa aatagtagtt aataatcttc atacgaccaa
    11881 caaaggtagt taaatctcgt ttgtttctat caaaaagaga ttgtttttac aagaaaaagt
    11941 taagtgcgga ttacactgac cacgcggaag attgaaaatc cgtgtaatct gcgtaatccg
    12001 cacttaaata tcaaagaaat gcagcattcg tctgcacctt cccattaatg gttttacccc
    12061 aaagtcttac ctgacgacag agtgaattac tctgctgcag gagcaggagt ttcagcagcc
    12121 ggtgccggag tttctgtagc aggtgcattg gtagcaggag cttcagtttg cggcgcagcc
    12181 gtacctgcgg gtaagttata cgggttagtc tgttgttctt tctgtgcctg ttccaacact
    12241 gcgtctttag caacagcaga gcgaggaact acataagcag tagcaatgct cattaccacc
    12301 atgaagatag ctaagcccca tgttgctttt tccagaaaat ctgtagtctt gcgcacgccc
    12361 atgatggcgt tagatgaaga gaaaccagaa gcaagtccgc ctccttttga gttctgaatc
    12421 agcacgatga aacacatcaa caaggctgca ataaccatta agataacgaa taataagtac
    12481 atttttagtt attttgaatt agcgttaata atcaatttct ccaaaaatct gatttggtct
    12541 gcaaagtaag catttttttt tggatatttc aagcttaatt ttttaattat ttcaagagct
    12601 tttgaatatc gttgctgttt aacatagatt tttgccaaag tttccgtaaa acagctgtca
    12661 tcttcctctt cttccttcat cgtttcttct tcggtaagtt cgtccgaaga ggttggcgaa
    12721 gatggcattt cttctcttaa aggtttcatg cagaggggag agtcgctctc gctcttttct
    12781 ataaagtcgt caatcagttc gtagcctttg agtttgggcg tttcttcggc cggctgttcc
    12841 gtggccggag tctcctccaa aagataagag gtgtaatcca tcgaatagtc gaagctggtg
    12901 cgggcagtca cttcttcggg ggctgtggac aagaaagcgt cgatcaatgc taatgtgcgg
    12961 tctacagatg gttcgtcttt cagtacctcc gtgagaggta ctcccttttt ccgtgcttgc
    13021 acatcatagc ggtcaccttc aatcaaccgg aacaactgcc gtctgtctgc aatgtaaaga
    13081 actgctttcc gcagttctcc accgaaacta atatcatgga gaatatacag attcttcaga
    13141 tacagcagac gaagtgactg aaaatacgga tacctcgcaa gaagattgcg cagttcgtac
    13201 aaagtatccc tattcagcgt ctcgggatgc tgaatccatt gttgaaagtt aacagaagtc
    13261 atttatatta ccagtttgct acagttgcat taaaaatttg gtcggtgatc tctttagaca
    13321 tttcagcaat caatccgtcc tgtacggcag tcagcaactg gctagagtcg taggtacgga
    13381 acgcagaaaa ctgttgttca aagtcttcgg catgattggt gttgttgaca aaacgtacat
    13441 tgacggtaat agtcaacttc gtctccgaag agtaaccgtc ggcagatact gcctggttgt
    13501 actgattgta tcctgtgatt tctccgtcaa tctgcaagtc cgcattctga ttcggcttga
    13561 gcagttgcag acgggtctgc cggatgaaga tatctttcag gtcctcattg aatttggttg
    13621 ccaacggagc atatacatac tccgacttga tcgggaagtc ggctatcgaa atggtcttta
    13681 ccttatcata attgatagac gatccgttaa acttatagga aacagtgcac gcaatgacta
    13741 ccaacggcaa gccgaacagt aacaaagggc gtattatttt cttaatccaa ttcatattct
    13801 tttatttttc tataaagtgt acgctcggaa atattcaagt ccttggccgc actcttccgc
    13861 tttccatgat gcctctcaag tgccttgcgt atcatttctt tctccacttc gtccagtgac
    13921 aaaggagatt cttctacata ttcttccgtg tcttgtatgt catcatcatc cttgcaaacc
    13981 gtaggctgca tggtgtgaat aatagcaggt accgaaggtt gatgcgccgt cactaccgga
    14041 gtagtaacca ccgttcccat ttgtcctacc tgccccacct gtccggcacg ttccgccatc
    14101 aggttgtgca ccatcttctt cagctccgcc acttcctggc gcatatcgaa cagaacggaa
    14161 taaagaatct cccgttcgct ctcaaagcct ttactctcac gcgttcccat cagcgcggga
    14221 agacgttgcg tattttgtgc gggaagataa ttctgcaaga tagcagcaga gatctcccta
    14281 ttggtttcaa tgatagatat ttgctcggtg atgttcttca actgacgcac gtttccgggc
    14341 cacgggtaag ctaacaactc tttcttcgca tcctccgtca actgaatagc aggcatccga
    14401 tatttctctg caaagtctgc ggaaaactta cggaacaaca aaagtacatc gtcaccacgt
    14461 tcacgcaaag gcggtatttg gataggcacc gtattcaacc ggtaatataa atcttcacgg
    14521 aaacgtcctt ctgcaatcgc ttgtgtcaga ttgacgttgg tagctgccac cacacgcaca
    14581 tccgtttttt gtactttgga cgaacctact ttcataaact cgccactctc cagtacacgg
    14641 agcaaacgtg cctgggtaga catcggcaac tcccctactt catcaagaaa aatagtacca
    14701 ccgtcagctt cgccaaagta ccctttccgt tcgccaatcg caccggtaaa cgcacctttc
    14761 tcatgtccga acagttcgga atcaatcgta ccttccggaa tagcgccaca gttgacagca
    14821 atatactgtc cgtgcttcct ccggctatat tgatgaataa tctgcggaaa actttctttt
    14881 ccgactccac tttctccggt aatcagcaca gacaaatcgg taggagctac ctgaatggca
    14941 acatctatgg cgcgcgacaa tgcttcagta tttccaataa taccaaaacg ctgtttcact
    15001 tgttgtatct ctgctttcgt catcactcgt ttttaatctt cgtctactgt atccagcttc
    15061 agtttatcac tatcgtcacg tttctcgtaa tactgtttac gcaacggatt ggcacgagcc
    15121 actttttcac gctgacgatt acggaacacg tcgatggcaa catagattgc ctggcggaaa
    15181 gaatcttcac aagccactcc cttgcctgca atatcgtat
//
