LOCUS       c00026_gnlPro..        17000 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IBBNHGCA_26.
ACCESSION   c00026_gnlPro..
VERSION     c00026_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 04:14:26
            Original ID  :: gnl|Prokka|IBBNHGCA_26
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5891
            Orig. end    :: 22891
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17000
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[15891:18864]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12973
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17000
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17000
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(1560..2117)
                     /locus_tag="ctg26_6"
                     /transl_table=11
                     /translation="MVYVMRNGRRVIAALSFLLLCCGVHVHAQRVAVKTNALGWLTASP
                     NVEAEFVLGSHVSLNMGIAANPISTDNFKTTFTHFQPEVRYWLNRPMVSHFLGITAFVN
                     NFDMMVKDVHHKGDAYAAGLTYGYAWVLGDHWNIEATAGVGVLRYRQFKYDKGTPKPGA
                     VNDSKTTIAPVKLGVSFVYIIR"
     CDS             complement(2347..4845)
                     /locus_tag="ctg26_7"
                     /transl_table=11
                     /translation="MYWKSHATEVYVKGETFDHAGGEKAPYPTVRYTGTRGTAATHGRP
                     KLADVVPYDDEDGNVTFCNNALPDRPMESVHPSKTGRNIESLNCEILGIARDAAFLYWM
                     TDEEKFAKLAAGVFDTYMTGIYYRNVPIDLNHGHQQTLVGLTSFEVIHEDALHIAVPLY
                     DFLYNYLKANYPDKMEIYAGAFKKWADNIIANGVPHNNWNLLQARFIMNVGLVLEDNKE
                     YADGKGREYYIDYVMNRSSIRQWSLTQLADYGFDINTGIWAECPGYSSVVINDYANFVN
                     QFDTNLQYDLVKAMPVLSKAVATTPQYLFPNRMICGFGDTHPGYLSTNFFIRMIQNAQA
                     NGKKEQENYFTALLKCLNPDLGNDKTEKKNVRVSVNSFFEDKPLALNPKVQPGKIEDYV
                     SPLFYAPNVSWLVQRNGMHPRNSLMISLNGSEGNHMHANGISMELYGKGYVLGPDAGIG
                     LFLYSGLDYAEYYSQFPSHNTVCVDGISSYPVMKSNHSFDLLSCFPASAEPGKAFTSVT
                     YSNLYFREPESRADQTRMMSIVTTGAETGYYVDVFRSRKEKGGDKMHDYFYHNLGQTLT
                     LTAADGSDLNLQSTEELAFAGAHLYAYSYLYDKKVAATNKDVKATFTIDMKDKDGDDIY
                     MNLWMKGEPDREVFTALAPMTEGLSRTPNMPYNIKEQPTLTFVARQHGEAWNRPFVSIY
                     EPSTKKEPSAIQSVSYFDAEGAGLEDFAGICVKSKNGRIDHIFSLSDAAQTAIYQGMKV
                     KADYAVISNEYAGNRTLFLGNGTQLVAPGVMIQTDNAANVLLEKKEGKWYIISSAPCTV
                     VIGDKKIKSDASSEPMLLRI"
     CDS             5549..7171
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH_4Fe-4S"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_8"
                     /sec_met_domain="Fer4_7 (E-value: 2.2e-10, bitscore: 31.4,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 5.1e-11, bitscore: 32.7,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.3e-50, bitscore:
                     161.7, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00039, bitscore: 11.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="NADH_4Fe-4S (E-value: 3.5e-34, bitscore:
                     107.0, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIIPDNTFYTQVTPEDAEEIINEHIIGGRRIERLLYVDPKTEHT
                     VSDSKHMDFYRKQLRIALRNCGFIDPENIEEYIAREGYFALADCLLNKQPTDVIDIIKR
                     SGLRGRGGGGFPTGLKWEFANKQQSDVKYVVCNADEGDPGAFMDRSIMEGDPHSIVEAM
                     CVCGYSIGSTKGLVYIRAEYPLAINRLKTAINQAREYGLLGDHILGTDFSFDIEIRYGA
                     GAFVCGEETALIHSMEGKRGEPTLKPPFPAESGYLGKPTNVNNVETLANIPIILTKGAD
                     WFATIGTERSKGTKVFALAGKINNVGLIEVPMGTTLREVIYEIGGGIKGGKKFKAVQTG
                     GPSGGCLTEKHLDTPIDFDNLLSAGSMMGSGGMIVMDEDDCMVSVARFYLDFTVEESCG
                     KCTPCRIGNKRLLELLNKITEGKGTEKDLDTLATLGQVIKDTALCGLGQTSPNPVLSTL
                     DNFYDEYMEHVRDKTCRSKQCKSLLTYTISPERCIGCHLCAKNCPADAISGLVRKPHVI
                     APDKCIKCGMCMARCKFNAILVC"
     CDS             7120..8949
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH-G_4Fe-4S_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_9"
                     /sec_met_domain="Fer4 (E-value: 5.4e-10, bitscore: 29.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_4 (E-value: 4.2e-23, bitscore: 71.6,
                     seeds: 126, tool: rule-based-clusters)"
                     /sec_met_domain="NADH-G_4Fe-4S_3 (E-value: 3.9e-19,
                     bitscore: 58.4, seeds: 418, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRHVHGTLQIQRYSCLLKSITMEDKQITLQIDGHFITVPEGSTIL
                     EAATKIGINIPTLCHIDLKGTCIKNNPASCRICVVEVIGRRNLAPACATRCTEGMVVKT
                     STLRVMNARKVVAELILSDHPNDCLTCPKCGNCELQTLALRFNIREMPFNGGELSPRKR
                     EITASIVRNMDKCIFCRRCESVCNDVQTVGALGAIRRGFNTTIAPAFDRMMTESECTYC
                     GQCVAVCPVGALTERDYTNRLLDDLANPDKVVIVQTAPAVRAALGEEFGFPPGTLVTGK
                     MVYALRELGFDYVFDTDFAADLTIMEEGSEILNRLTRYLNGDKSVRLPILTSCCPAWVN
                     FFEHHFPDMLDIPSTARSPQQMFGSIAKSYWAEKMGIPREKLVVVSIMPCLAKKYECAR
                     DEFKVNGIPDVDYSISTRELARLIKRANIGFPLVLDSPFDNPMGESTGAGVIFGTTGGV
                     MEAALRSVYEIYTGESLKNVNFEQVRGLNGVRRATINLNGFELKVGIAHGLGNARHLLE
                     DIRNGHNEYHVIEIMACPGGCIGGGGQPLHHGNSEILYARANALYREDANKPLRKSHEN
                     PYIKTLYEEYLGKPLGEISETLLHTHYFNKSMD"
     CDS             8968..9495
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_10"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 1.5e-47,
                     bitscore: 151.4, seeds: 130, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDIKLACDVAEQVRTICDKHGNNPGELINILHEAQHLHGYLPEE
                     MQRIIASKLNIPVSKVYGVVTFYTFFTMTPKGKHPISVCMGTACYVRGSEKLLEEFKRV
                     LGIEVGETTPDGKFSLDCLRCVGACGLAPVVXXXXIATDRCEEDYRGVGINVRNKKVAA
                     LKNQGSRFQTFF"
     CDS             10001..12229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_11"
                     /sec_met_domain="Gly_radical (E-value: 8.1e-47, bitscore:
                     148.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1172.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSTEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERANNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLRNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYMEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     NFEEVMSNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIQGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATEEDRVENLVTMMDGYFTKGAHHLNVNVLN
                     REMLYDAMEHPEKYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             12245..12973
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74.2;
                     E-value: 4.3e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_12"
                     /sec_met_domain="Radical_SAM (E-value: 7.2e-30, bitscore:
                     94.9, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGVTFSGGEPTFQAKALVPLVRELKEKGIHVCIDSN
                     GGIWNEEVEELFKLTDLVLLDIKEFNPARHQALTGRSNEQTIRTAAWLEENEKPFWLRY
                     VLVPGYSDFEEDIRRLGEALGKYKMVQRVEILPYHTLGVHKYEAMEQEYKLKDVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(13001..13444)
                     /locus_tag="ctg26_13"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRADRDFTAKDVDTAHRFRGFSCWGYHYYIRK
                     SGQIEPMRDEDTVGAHARGFNAISLGVCYEGGLDENGKAADTRTSRQKEAMHRLVNELL
                     QRYPDAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVKAETW"
     CDS             complement(13619..14122)
                     /locus_tag="ctg26_14"
                     /transl_table=11
                     /translation="MAMTVTYSVVPRKNPAKKDESAKYYAQAQASGELDFEELCEGITS
                     RSTCTETDVRAAISGILYEAKRALKAGRIVRLGDLGSLQIGLNSEGAVSVKEFSSSLIT
                     AAHIIFRPGKTLADITKILSYQQVTTRAVAQTGGSGNEGEDDDKGSGGGSDGGGSGEAP
                     DPAA"
     CDS             14316..14546
                     /locus_tag="ctg26_15"
                     /transl_table=11
                     /translation="MYYPDQPFHICTYKKSELAHLYNPNVCLKVALQILRRWIVYNLPL
                     LQELEQEGYRARNRLLSPRQVATIIRYLGEP"
     CDS             complement(14844..15326)
                     /locus_tag="ctg26_16"
                     /transl_table=11
                     /translation="MVVECHLFGEGIVVWCCRLFLFAGCPFLLLRLEEYRWLFHDDSCG
                     IGIEINIRIVREQASTADILSGSVDLNSAELGIKGSDFVISGMMEIFNFLNRFGQCPVR
                     PAYTYHDFQSHSFGTDESDAGVGTLFCQCEDACQCFLCLMVDVYHDVSQILDESCV"
     CDS             complement(15591..15821)
                     /locus_tag="ctg26_17"
                     /transl_table=11
                     /translation="MVGAAEVGVDQILNRLDGARIAQFVHLHPNAVFHHFVENMERFRL
                     LRVRFPSAIFHDMKHFVVACIVIFFDMLLNL"
     CDS             16065..16751
                     /locus_tag="ctg26_18"
                     /transl_table=11
                     /translation="LRAYLSTGLINPNNKDDLAKIAQAMLINLDEFEGMNGRELNIFKD
                     LVTRKVISIRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHVNSMEFIKIN
                     YAQLYAQIKYLLNKPGYQYWFTQSENSRIEENNEDFIFHSPEEELVLTHIRKPERFEKV
                     HYLTVTEIAELIRERTGYQYSHGTKAQLGKVMSKHGFEFHKGKNGRRYTVFIIDTEQVK
                     SNRLYE"
     CDS             complement(16883..16999)
                     /locus_tag="ctg26_19"
                     /transl_table=11
                     /translation="NNKAPACESRGFVRKKQKVCILTHLRFFEEEKGKGEGR"
ORIGIN
        1 ttcattggct gcatacgtaa agttatcata aagttcaaga gcttccctac aatacttttc
       61 cctttcgtcg ggagtttttg ctgtcgtaat catacggtaa tattcgaaac gggtcagttc
      121 cttcggattc tttctgtaaa gttctctaat ctcgtcgtcc gtcaaagaac ggaagattga
      181 ataaccatag gtatattgca cctttctcaa tttaggcaaa taagtagccg caagttcctt
      241 gtagaaaggt ttcgatttca agaccccatt caaccggtaa ggagtagctg tatattgttt
      301 gattaagtcc tctacttctt tagccagttc cggcttggag ttttttttca gcaattcagc
      361 tacctccttc caggaggcaa ccgatgcatc cgatttcacc tccaacagtt tacgtgtttc
      421 cgggtccagt tgtgccagta tacgttccag ggccttatcc gtacgcaatt ttgccagacg
      481 aagattcgtc gcgtaagaac cgtccggcga agccaccccc gtaatatgaa aactcttcaa
      541 agaggcatcc gggttcgtct caataccacg caattcctga ttcaaccggt tcagttccac
      601 ctgattttgt ggattcttat catccaggtc ggctttacct accaggaagg ttaagtttac
      661 ctcacctttc gtatcccgca actgcatcac gggtttcgga aggtatttct cgtccgtcag
      721 gctgaaagcg gagaatttat actccaagaa gcgaagcggg ttgaccgttc cgcgtgcaat
      781 ggagaaagag tcacgataaa tgatattccg gtaattttcc atcgccagat gcacatctgc
      841 acggtagtca tgttgcagat attctatata gatagaatca tggtaagcaa taatatcccc
      901 cttgcgtgaa gaagtagttt tcacacggat gtaatcgtgc aaaggatctt tatccatatc
      961 ataatcgtac attcgatttt gcgttgtatt ataagtatcc ccgtcgaata caacaggacg
     1021 catcaacaga cgctttttca gtgtcacatc ataaatggaa ggctgcaata ccaagcgacg
     1081 atgtgagtta aacatctcct taggcaccgg gacacgagtt ttcagatgga aataattacc
     1141 tttgatttcg atgtccgtag gttccggaat cactttgtcc ttcactttgg aagtaattgt
     1201 aacttcgtcc agttcgatga cggcatcttt caatactaca ttcagaatct gctttcctgc
     1261 caccttcact gttttgtctt cataaccgac acatgtaaac ttcaacgagc cgtttttctc
     1321 aaccaagaca ctgtaacggc catcctcgtc ggacatttct atacgttcgt cattgaccgg
     1381 attcaacaca tttacattcg gaacactttt tccctgcggg tttgtgatat gcccctgcac
     1441 gcggatccgt tgggcggata cattcatacc gacgaacatc atcgccacga gaagtatacc
     1501 tgttaatcta tcacgtttca aattgatttt cattctcttt tctgactagc taatgttcgt
     1561 tatcgaataa tataaacaaa ggataccccc agtttgacag gtgcaatggt ggtcttacta
     1621 tcgttgaccg cacccggttt cggagtaccc ttatcatact taaactgacg gtagcgcaac
     1681 acacccactc cggcagttgc ttcgatgttc caatgatcgc ccagcaccca tgcgtatcca
     1741 taggtcaaac cggcggcgta tgcatcgcct ttgtgatgca catcttttac catcatatca
     1801 aaattattca cgaaagcggt gattccaaga aaatgactca ccatcggacg atttagccag
     1861 taacgaactt caggctgaaa atgcgtgaaa gtcgttttaa agttgtctgt actgattggg
     1921 ttcgcagcaa tccccatgtt caaggagaca tgactaccca atacaaattc tgcttctaca
     1981 ttcggactgg cggtcagcca acccaatgca tttgtcttta cagccacccg ttgtgcgtgc
     2041 acatgtacac cacaacataa taacagaaat gataacgcag ctattaccct gcgaccattt
     2101 ctcatcacat ataccatcat ttatttccca ctaaatattt cccactaaat atttacccac
     2161 aaaaaaaggg cttactgtcc attttatata ctacttggac agaaagccac aaaattagaa
     2221 aaaatatagt attaaaaacg tttaaacacg ctttttttgt tttttattgc aacaatttcc
     2281 atcttaggcc ataatatacc atactacgga taagatatac aatttttctt tattaccaat
     2341 gaaacatcag atacgcaaca acataggctc cgacgaagca tcggatttta tcttcttatc
     2401 gccgataaca accgtacagg gagcagaaga aataatatac catttccctt ctttcttttc
     2461 gagcaataca ttagcggcat tgtcggtctg aatcattacc ccgggtgcaa ccaattgggt
     2521 cccattccct aaaaacaacg tccggtttcc tgcatattca ttgctgataa cagcataatc
     2581 cgctttcact ttcattcctt gataaatagc ggtttgtgca gcatcagata gagagaagat
     2641 atgatctata cgtccgtttt tgcttttcac acagataccg gcaaagtctt ccaaacctgc
     2701 tccttctgca tcaaagtaag agacggactg aatagcagac ggttcctttt tcgtactcgg
     2761 ttcatatatc gagacaaaag gacgattcca agcttctcca tgctgacggg caacaaatgt
     2821 cagcgtcggc tgctccttta tattataggg catattcggt gtacggctta gcccttcggt
     2881 cattggcgcc aaagccgtaa agacttcacg atccggttcg cctttcatcc aaagattcat
     2941 gtatatatca tcgccgtcct tatctttcat atctatggtg aaagttgcct tgacatcctt
     3001 attggttgca gccactttct tatcatataa ataggaataa gcgtaaagat gtgcgcctgc
     3061 aaaggcgagt tcttccgtag actggagatt caggtcgctg ccatctgctg ccgtcaatgt
     3121 caaagtctgt ccaaggttgt gatagaagta atcgtgcatc ttatcgcctc ctttctcttt
     3181 ccggctgcgg aatacatcga cataataccc cgtctccgcc ccggtagtga caatactcat
     3241 catacgggtc tgatccgccc tgctttccgg ttcacgaaaa taaaggttac tgtaagtaac
     3301 ggacgtaaat gctttgcccg gttccgctga tgccgggaaa caggaaagca aatcaaaaga
     3361 atgattactt ttcatcaccg gatagctcga tattccatcc acacaaactg tattatgact
     3421 ggggaattga gaataatatt ccgcataatc cagtccgcta tacaggaaaa gcccgatacc
     3481 tgcatccggc cccagtacgt atccttttcc ataaagttcc atcgaaatgc cgttagcgtg
     3541 catgtggttc ccttcactgc cattcaacga aatcatcaaa ctgttgcgcg gatgcatacc
     3601 gttgcgctgt accagccatg acacattggg agcataaaac aaaggagaaa cataatcttc
     3661 tatctttccc ggctgcactt tgggatttag cgccagcggt ttatcttcaa agaaagaatt
     3721 gacagataca cgcacattct tcttttctgt tttatcattt cccaaatccg ggttcaggca
     3781 tttcaataaa gccgtgaaat agttttcctg ttctttcttc ccgttcgcct gtgcattctg
     3841 tatcatacgg ataaagaagt tcgtactcaa atatcccgga tgcgtatctc caaagccaca
     3901 aatcatacgg ttgggaaaca gatattgggg agtggttgct accgctttcg acaatacagg
     3961 cattgctttc accaaatcat attgcagatt cgtatcaaac tgattcacaa aattggcata
     4021 atcattgatt accacactgc tatatcccgg acattctgcc caaattcccg tatttatatc
     4081 gaaaccataa tctgccaatt gcgtcagact ccattggcgg atgctggaac ggttcatcac
     4141 atagtcgata taatattcac gtccttttcc gtcggcatat tctttattgt cttccaatac
     4201 caatccgaca ttcataataa accgtgcctg tagcaaattc cagttgttat gaggtacacc
     4261 gttcgctatg atattatccg cccatttctt aaaagctccg gcgtagattt ccattttatc
     4321 cgggtaattg gcctttagat aattatatag aaaatcgtat aaagggacag cgatatggag
     4381 tgcgtcttca tggatgactt cgaaagaagt caatcctacc aatgtttgct gatggccgtg
     4441 attcaggtcg atgggcacgt ttctataata aatacctgtc atatatgtat caaagacccc
     4501 cgcggcaagt ttagcgaatt tctcttcatc cgtcatccaa taaaggaaag cggcatcacg
     4561 ggcaattccc aggatttcgc agttcaggct ttcaatattc cggcctgttt tggatgggtg
     4621 tacactctcc ataggacggt cgggaagtgc attattgcag aaagtgacat tcccatcctc
     4681 atcatcataa ggaacgacat ccgccaattt gggacggccg tgggtagcag ctgtgccacg
     4741 ggttcctgtg taacgcacag tgggataagg agctttttca ccacctgcat ggtcgaacgt
     4801 ttcacctttc acatatactt ccgtggcatg agacttccag tacattgcca aacgagacag
     4861 caaccacgcc ggttgagcat ccgtcaggtt cgtatatact tccgtccgtt ccttcaattt
     4921 attgaaaaca tctttcgccc attcttcttt tttaatcagc ttccatgttt cctgctttcc
     4981 cgccggagta gtcagtaccc gcggatgtgt ctgcggcatc ttttccggca aaggaatctc
     5041 ttgtccggat gcgctgttca gaaaggatag aaaacatagt ccaagtaaaa ttcgtctcat
     5101 acttcaattt tcttttttta ggtttgatac ctattaaata cgaagataga gatttattta
     5161 cctaaatcct ccgtcaaaga acaattttat ttgtacgaga ctacgctgtt atttcaaaca
     5221 aagaattata tttgcaaaaa accgactaac aattctgata cttatgaaaa ttttatctat
     5281 ccatgatttg gcaacaatca ggaagagagc agagcacaat ctttcattgc gcgaagaaag
     5341 taatgaaaag gtgactgaaa agtgttacgg actggcatcc ggtgcgcaac atcttcagat
     5401 tctgatctgc ggtggtacag gctgtaaggc atcttccagc cagggtatta cagacaatct
     5461 tctaaaagcc atcaaaaaga acgaaatcac cgataaagta gaagtcatca ccgtaggctg
     5521 tttcggcttc tgtgaaaaag gtcctatcgt gaaaattatc cccgataata ccttttacac
     5581 ccaagtcact cccgaagatg cggaagaaat catcaacgag catatcatcg gaggacgaag
     5641 aatcgaacgg ttgctgtatg tagatcccaa aacggaacat accgtcagcg actccaagca
     5701 catggatttc taccggaaac aactccgcat cgcattgcgt aactgtggtt ttatcgatcc
     5761 cgaaaatatt gaagagtata tcgcccgtga aggatacttt gcattggccg attgcctgct
     5821 taacaaacag ccgacggacg ttattgatat tatcaaacgt tcgggacttc gcggacgtgg
     5881 tggtggcggt ttcccgacgg gactgaaatg ggaatttgcc aacaagcaac agtcagatgt
     5941 caaatacgtg gtttgtaacg ccgacgaagg agatcccggt gcattcatgg accgttccat
     6001 tatggagggc gacccacatt cgattgtaga agcgatgtgt gtctgcggtt attccattgg
     6061 ttccaccaaa ggattagtat atatccgtgc ggaatatccg ttagccatca accgactgaa
     6121 aacagctatc aatcaggcac gcgaatacgg attattggga gatcatatct taggaacaga
     6181 tttcagtttc gacatagaaa tacgatacgg agccggagct tttgtatgcg gagaagaaac
     6241 tgcccttatt cattcgatgg aaggaaaacg gggagagccg actctgaaac ctcccttccc
     6301 tgccgaatcc ggttatctgg gaaaaccaac caatgtgaat aatgtggaaa cgcttgccaa
     6361 tattcccatt attctaacca aaggagccga ctggtttgca acgattggca cagaacgttc
     6421 caaaggaacc aaagtgtttg ctcttgccgg aaagattaat aatgtcggac tgatcgaagt
     6481 gccgatggga actactcttc gggaagtaat ctacgaaatc ggaggaggca tcaaaggcgg
     6541 aaagaagttc aaagctgtac aaacaggagg accgtcaggc ggctgtctga cagaaaaaca
     6601 tctggacact cccattgact ttgacaacct tctctcggcc ggttccatga tgggttcagg
     6661 agggatgatt gtcatggatg aggacgactg catggtatcc gtagcccgct tttatctgga
     6721 ttttacagtg gaagagtcct gcgggaaatg cacaccttgc cgcattggaa acaaacgtct
     6781 gttggaacta ctgaacaaga ttacagaagg aaaaggcaca gaaaaagacc tggacacact
     6841 tgccactttg ggacaagtca tcaaagatac ggccctctgc ggactgggac aaacctctcc
     6901 gaatcccgtt ttatccacat tggataactt ctacgatgaa tatatggaac acgtacggga
     6961 taagacttgt cgttccaagc aatgtaaatc actattaacg tataccatca gtccggaacg
     7021 ttgcattggt tgtcatctat gcgccaaaaa ctgtccggcg gatgctatca gcgggctggt
     7081 gcgcaagcca catgtcattg ctcccgataa atgtatcaaa tgcggcatgt gcatggcacg
     7141 ctgcaaattc aacgctattc ttgtctgcta aaatcgatta ctatggaaga taaacaaatc
     7201 accctccaga tagacggcca tttcatcacc gtccccgaag gaagtaccat ccttgaagcc
     7261 gccacgaaaa tcggcatcaa cataccgacc ctgtgtcaca tcgacctgaa aggcacctgc
     7321 ataaagaaca atcctgcttc ctgccgcatc tgcgtggtcg aggttatagg acgccgcaat
     7381 ctggctcctg cctgcgctac ccgttgcaca gaaggaatgg tagtaaaaac cagtacgcta
     7441 cgtgtgatga acgcacgcaa agtggtagcc gaacttatcc tgtcggatca tcccaacgac
     7501 tgtctcacct gccccaaatg tggcaattgc gaacttcaga cattagcgct acgctttaat
     7561 atccgcgaaa tgcctttcaa tggaggcgag ctctctcccc gcaaacggga aatcactgcc
     7621 tccatcgtgc gcaacatgga taaatgtatt ttctgtcgcc gctgcgaaag tgtctgtaac
     7681 gatgttcaga cagtcggtgc gctcggtgcc atccgtcgcg gattcaacac gacgatagcc
     7741 cctgcctttg accgaatgat gacggagagc gaatgtacct attgcggaca atgcgtagct
     7801 gtctgtccgg tgggtgcact gaccgaacgc gattatacga accgcctgct cgacgactta
     7861 gctaacccgg ataaagtggt gattgtgcaa acagcccctg ccgtacgtgc tgccctgggc
     7921 gaagaattcg gttttcctcc cggcacactg gtaaccggaa aaatggttta tgccctgcgt
     7981 gaactgggat tcgactatgt attcgatact gactttgccg ccgacctcac catcatggaa
     8041 gaaggatcgg aaatactaaa ccgtctgacg cgctatctca acggagataa gtccgtacgg
     8101 ttacctatcc tgacctcctg ctgtccggca tgggtgaact tcttcgaaca tcacttcccg
     8161 gatatgctgg acattccatc caccgcccgt tcaccgcaac agatgttcgg ttctatcgcc
     8221 aaatcctatt gggcggaaaa gatgggaatc cctagagaaa agctggtagt cgtatccatc
     8281 atgccctgtc tggcaaaaaa gtatgaatgt gcccgcgatg aatttaaagt gaacggtatt
     8341 cccgacgtag attattctat ttccacccgc gaactggcac gactgattaa acgcgccaat
     8401 atcggcttcc cgctggtact ggacagcccg tttgacaacc ctatgggtga gtcgaccggt
     8461 gccggcgtta ttttcggtac aacaggtggt gtaatggaag ccgccctccg ttctgtttat
     8521 gaaatctata ccggagaatc tctgaaaaat gtaaacttcg aacaagtacg cggacttaac
     8581 ggtgtccggc gtgctaccat caacctaaac ggatttgaat taaaagtagg catcgcacac
     8641 ggactaggca acgcccgcca tctattggaa gatatacgga acgggcacaa cgaatatcat
     8701 gtaatcgaaa ttatggcttg ccccggaggt tgcatcggag gaggcggaca gccgttgcat
     8761 cacggcaact cggaaatatt gtatgcacgc gccaacgcac tctaccgcga agacgccaac
     8821 aagcctttgc gcaaatcgca cgagaatccg tacatcaaga ccttgtacga agaatatctc
     8881 ggcaaaccac tgggcgagat atcggaaacg ctattgcaca cgcactattt caacaaatct
     8941 atggattaac tttaaacgaa gagtattatg tcagatataa aactagcctg cgatgtggca
     9001 gaacaagtcc gaacgatttg cgacaagcac ggaaacaacc cgggcgaact aatcaatatt
     9061 ttgcacgaag cgcaacacct gcacggctac ctgcccgaag agatgcaacg catcatcgct
     9121 tccaaactca atatccccgt atcgaaagta tatggagtgg tcaccttcta taccttcttc
     9181 accatgaccc cgaaagggaa acatcccatc tccgtctgca tgggtacggc atgttacgtg
     9241 cgcggctccg agaagttact cgaagaattc aaacgcgtac taggcatcga agtcggcgaa
     9301 accacaccag atggaaaatt ctcattggac tgcctgcgct gcgtaggtgc ctgcggactg
     9361 gctccggtag tgnnnnnnnn nnngattgca accgatagat gtgaagaaga ttatcgagga
     9421 gttggaataa atgtccggaa taaaaaagtg gctgctttga aaaatcaagg cagccgcttt
     9481 caaacatttt tttaacaaca aacaaaaaag cggagagaac gagattcgaa ctcgtgatac
     9541 cctttagggg tatacacgct ttccaggcgt gcctcttcaa ccactcgagc acctctcctt
     9601 attttccaat aaaaacagac aatggaaata tattttccac aaaagaaata gcagcttaaa
     9661 agctgctatc ctagcggaga gacagggatt cgaaccccgg gtacctcgcg gtacaacggt
     9721 tttcaagacc gccgcaatcg accactctgc cacctctcca aaacttcctt ttcagaagtg
     9781 ctttttgtta aaagcggtgc aaaggtacga atatatttta aacttgcaag agttttcaca
     9841 aaaaaaaatc acgaacatca tttccaaaga atagctatat ctaggtattt tatgttgaaa
     9901 agcataaaat acagcatatt tatgctgatt atatgaaaaa acgttgtaac tttgtgcgct
     9961 ctaaagaaaa ggataactac aacctctaat tttatcattt atggaattaa ataagatctt
    10021 taaagacggt ctttggagca cagaaatcaa cgtaagagat ttcgttagtc acaacatcac
    10081 tccgtattat ggagatgctt ctttcctcga aggacctacc gaacgcacta aagctgtatg
    10141 gaaccgctgc ctcgaagcac tggcagaaga aagagccaat aacggagtac gctcactgga
    10201 taatgtcacc gtctcaacca tcacttctca taaagccgga tatatcgaca aagaaaacga
    10261 actgatcgtc ggtctgcaaa cagacgaact tctgaaacgt gcaatcaaac ctttcggagg
    10321 tatcaacgtg gtgagcaaag cctgccacga aaacggcgtg gaagtggacg accgtgtaaa
    10381 agatatattc actcactacc gcaagacgca caatgacgga gtatttgacg tatataccga
    10441 agaaatccgt tcgttccgtt ctctgggatt cctcaccgga cttcctgaca actatgcccg
    10501 cggacgtatc atcggcgact accgccgtat ggctctctat ggtatcgacc gactgattga
    10561 ggcaaaaaaa gaagatttgc gtaaccttac cggtccgatg accgaagccc gcatccgcct
    10621 gcgcgaagaa gtggcagagc aaatcaaggc attgaaagac atgaaagtaa tgggcgaata
    10681 ctacggactc gacttgagcc gtcctgccta caccgcacaa gaagcagtac aatgggtgta
    10741 catggcttac cttgctgccg taaaagaaca agacggtgct gccatgtcac tgggtaacgt
    10801 ctcttcgttc ctcgacattt atatggaata tgaattgagc aaaggaacta tcacagaatc
    10861 tttcgcacag gagctgatcg accagtttgt catcaaactg cgtatggtgc gccacctgcg
    10921 tatgcaatct tacaacgaca tctttgccgg cgacccgaca tgggtaaccg aatccctggg
    10981 cggacgcctc aacgacggac gcaccaaggt gacaaagact tctttccgct tcctgcaaac
    11041 actctacaac ctcggccctt caccggaacc gaacctgact gtattgtgga gcccggaact
    11101 gccggaagga ttcaaagaat tctgcgcaaa agtatctatc gacacttctt ccatccaata
    11161 tgaaaacgac gacctgatgc gtgaagtgcg ccagtctgat gactacggaa tcgcgtgctg
    11221 cgtatcttat caggaaatcg gaaaacaaat ccagttcttc ggcgcacgtt gcaacctggc
    11281 taaagccctg ctgcttgcca tcaacggcgg acgttgcgaa aacaccggta cggtaatggt
    11341 gaaaaacatc cccgtactaa ccagcgacac actgaacttc gaagaagtaa tgagcaacta
    11401 caagaaggta ttgacagaaa tcgcccgtgt ttacaacgaa gcgatgaaca tcatccatta
    11461 tatgcatgat aagtattact acgaaaaagc ccaaatggct cttgtagata ccaacccacg
    11521 catcaacctt gcttacggtg tagccggact ttctatcgcc ctcgattcac tgtcggccat
    11581 caaatatgcc aaagtaaccg cacgccgcaa cgacatcggt ctgacagaag gtttcgatat
    11641 tcaaggcgaa ttcccttgct tcggtaatga caacgacaag gtagaccacc tgggtgttga
    11701 cctggtctat ttcttcagcg aagaattgaa gaaacttccg gtttacaaaa atgcccgtcc
    11761 tactctgtct ttgctcacca tcacttccaa cgtgatgtat ggcaagaaga caggtgctac
    11821 tcccgacggc cgcgccaaag gtgtcgcttt tgctccggga gccaacccta tgcacggacg
    11881 tgacaagaac ggtgccatcg cctctttgag ttccgtagcg aaattacgtt accgcgactc
    11941 acaggacggt atcagcaaca ccttctccat cgttccgaaa tcactgggag ctactgaaga
    12001 agatcgcgta gaaaatctgg tgacaatgat ggatggttac ttcaccaaag gcgctcacca
    12061 cctgaacgtg aacgtactga accgtgaaat gctttacgac gccatggaac atccggaaaa
    12121 atatccgcaa ctcaccatcc gtgtttccgg ttatgccgta aacttcgtga agttgagccg
    12181 cgaacatcaa ttggaagtta tcagccgtag cttccacgaa cgtatgtaat cagatctact
    12241 caatatgacg ataaacgtac attcatacga aagtatggga acattcgacg ggccgggctt
    12301 acggctcgtc gtttttcttc aaggatgcaa tttccgctgc ctgtattgtg ccaatcccga
    12361 cacgatagcc ggaaaaggag gtacacctac cccaccggaa gaaatcgtcc gcatggctat
    12421 gagccaacgt ccttttttcg ggaaacgcgg aggagtcact ttctccggag gagaacctac
    12481 gtttcaggcc aaagcactag tccctttagt gcgtgaactg aaagaaaagg gaatacatgt
    12541 atgcatagac agcaacggcg gtatctggaa cgaagaagta gaagaacttt tcaaactgac
    12601 ggatcttgta ttgctggata ttaaagagtt caatccggca cgccatcaag cactgaccgg
    12661 aagaagtaac gagcaaacca tccgcacggc agcatggctg gaagaaaacg agaaaccttt
    12721 ctggctgcgt tatgtattag tgcccggata cagcgatttc gaagaggata tccgccgctt
    12781 gggagaggct ctgggaaaat ataagatggt gcaacgagtg gaaatcctgc cttatcatac
    12841 attaggcgta cataagtatg aagcgatgga gcaggaatac aagctgaaag acgtaaaaga
    12901 aaataccccc gaacaacttg aaaaagccgc ggaggtattt aaagagtatt tcactactgt
    12961 ggtggtcaat taaccaccac agtaataaat aggataaaaa tcaccatgtc tctgctttca
    13021 cctcgaaaca gggacactct ttgatccgct cccaagggtc aacaattcca ttataattgg
    13081 tgtcaggact caagtcccga tgaccgacca cctttgcatc cggataacgc tgcaacaact
    13141 cgtttaccag acgatgcatc gcctctttct ggcgggaagt acgcgtatct gctgcctttc
    13201 cgttctcatc cagcccgcct tcatagcaca ctcctaaact aatcgcatta aaaccgcgtg
    13261 catgagcacc caccgtatct tcatccctca tcggctctat ctgtcccgac ttgcggatat
    13321 aataatgata cccccaacaa gaaaagcccc gaaagcgatg ggcagtgtcc acatccttcg
    13381 ccgtgaagtc gcgatcagca cgggtagcag agcagtgaat cacaatcaga ctaatctttc
    13441 tcatcgtcct tctccctttc cgtcgttttc acattacaca cttccttatg ggtagcattg
    13501 aagcgcacct ctctcacaat tctgttccgc tttctttttc cgaagaaagg cacaaggaac
    13561 ataattacat ccaaaatctt agttacaatt tctttcattt gattcaatat taaagttatc
    13621 atgctgccgg atccggagct tctccgcttc caccaccgtc tgaaccgcca ccggaacctt
    13681 tgtcatcatc ttctccttca ttgccgctac cgcccgtttg ggccaccgca cgcgtcgtta
    13741 cctgctggta gctaagaatc ttcgtgatgt ccgccaacgt ctttccggga cgaaaaataa
    13801 tatgggcagc cgtaatcagc gaacttgaaa actccttgac cgacacagct ccttcactgt
    13861 tcaacccgat ctgcaaactg cccaaatcac ccaaccggac tattcttccc gctttcaacg
    13921 cacgcttcgc ctcataaaga atacccgaaa tggcggcacg cacatctgtc tccgtacagg
    13981 tagaccggct ggtgattccc tcgcacaact cttcaaaatc caactctccc gaagcctgtg
    14041 cctgcgcgta atactttgcc gactcatcct ttttggcagg attcttgcgc ggcactactg
    14101 aataagttac tgtcattgcc ataataaaat aattttaaga tttcacacat ttcgaacgcg
    14161 ttccttattt gttaacgaca taaagataac acatttttca ccctccggat tccccaacga
    14221 agtttcctga tactctatga ataataatga cgttattctt ttattaaacc attaattttc
    14281 agtaacttta tagcataaac caaatatcat tcatcatgta ttatccggat cagccgtttc
    14341 atatctgcac ttataaaaag tcggaactag ctcatcttta caaccccaac gtatgcctta
    14401 aagtagcctt acaaatacta cgtcgttgga ttgtctacaa ccttccgctc ctgcaagaac
    14461 tcgaacaaga aggctatcgt gcccgcaacc gccttctctc tccccggcaa gtggcaacga
    14521 tcatacgcta tttgggagaa ccctaggaac ttaatcaaaa aaacgaaaag ttccattcta
    14581 ttattttaca aacaaatttc tttgcaaccg caaattaaaa agaacaaacc aacatggagc
    14641 attttaccat ctttcaagac ttttaccgcg tcatagccga aatgacagaa gaagaaatcg
    14701 tatcggccat cagcaacggc acataccggg aaacagtgga ggacgtgcgc cgaatcttcg
    14761 cggaacaagg cgagaaagca gcaaacgaaa agaaaataga actaccggaa atcacctttt
    14821 cagccaacta ccggggagga cgttcaaacg caactctcgt caagtatctg ggatacatcg
    14881 tggtagacat cgaccatcag acacaggaag cattggcacg catcctcgca ctggcaaaaa
    14941 agtgtgccca cacccgcatc gctttcatca gtcccaaagg aatgggactg aaaatcgtgg
    15001 tacgtgtatg ccggacggac gggacattgc ccgaaacgat tcaggaaatt gaagatttcc
    15061 atcatgccgc ttatcacaaa atcgcttcct tttatgccca gctctgcgga gttgaggtcg
    15121 acacttccgg acaagatgtc agccgtactt gcctgttctc ttacgatccg gatatttatt
    15181 tcaatcccga tgccacagct gtcatcgtgg aacagccacc gatattcttc aagtctcaaa
    15241 agaagaaaag ggcatccggc aaaaagaaaa agacgacagc accagacaac aatcccctca
    15301 ccgaacaagt ggcactcaac taccattcct cgcacgcttc cttaatggtg actctgaact
    15361 attatcacaa taaatccgaa aagtacgtca ccggcaaccg gaacaactac ctgcattgcc
    15421 tggcttgtat gtacaatcgc tacggcgtcc cccaggaaga ggcggcagct tttatcaaga
    15481 gccagttcac cgatcttccc gcggatgaaa tggacgcact gatcgggagt gcttacggac
    15541 acaatgagga attcgacacc cgcaagctga atagtacgca gaagcgaata ttacagattg
    15601 agcaacatat caaagaaaat tacgatacac gctacaacga agtgcttcat atcatggaat
    15661 atcgcagaag gaaaacggac acggagcaac cggaaccttt ccatattctc gacgaaatga
    15721 tggaaaacag catttggatg gagatgaacg aactgggcta ttcgtgcacc gtcaagacga
    15781 ttcagaatct gatctactcc gacttcagca gcacctacca tcctattcgc gagtatttag
    15841 actcgctgcc tgaatgggac ggaacggatt atatcggtat ccttgccaac agcgtgcata
    15901 ctagtcacca gaaattttgg gtagaatgtc tggaacgtta tctggtggga atgtgcgctg
    15961 ccgccacgca agacgatgtg gtgaaccaca ctgttttgtt gctttgcagc gaaatacaga
    16021 acatcggaaa gactacgttt atcaacaacc tgctgccgcc cgaattgcgc gcctatcttt
    16081 ctaccggtct tattaacccg aacaacaagg atgatctggc caaaatagcg caggcaatgc
    16141 ttatcaatct ggatgagttt gaagggatga acggacggga actgaatatc ttcaaggatt
    16201 tggttacccg caaagtaatc agcatccgcc tgccatacgc gcggcgttca cagaacttcc
    16261 ctcacacggc ttcttttgcc ggcacatgca attatcagga agtgcttcac gacaccacag
    16321 gtaaccgccg ttttctctgc tttcatgtca actcgatgga gtttatcaaa ataaactacg
    16381 cgcagttgta tgcacaaatc aagtatctgc tcaacaagcc ggggtatcag tattggttca
    16441 cccaatcgga aaactcacgg attgaagaga acaacgagga tttcattttc cactcaccgg
    16501 aagaagaact ggtgttgaca catatccgca aaccggaacg tttcgaaaag gtgcattatc
    16561 tgacggtcac tgaaattgcg gaattgattc gcgaacgaac ggggtatcaa tattctcacg
    16621 gaaccaaagc ccaactagga aaagtgatgt ccaaacacgg cttcgaattt cataagggaa
    16681 aaaacgggag aagatacact gtattcatta ttgatacgga acaggtgaaa tcaaacaggc
    16741 tatatgaata agatttcatc tccttcgcac gcaaaaaggt gagggttggt gagggtactt
    16801 ttgcaacttt tcatttttat atttcttatt tctattcttc tattttcttc taaaaaaaaa
    16861 tacgaatgtt agaaatttac cctcacctac cctcaccttt tcctttttct tcctcaaaaa
    16921 aacgaaggtg tgtcaaaatg cacaccttct gttttttacg cacaaagccc cgactttcac
    16981 aagctggggc tttgttatta
//
