LOCUS       c00174_gnlPro..        16494 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KILNDFON_174.
ACCESSION   c00174_gnlPro..
VERSION     c00174_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 03:40:46
            Original ID  :: gnl|Prokka|KILNDFON_174
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 8762
            Orig. end    :: 25256
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16494
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[18762:22311](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..13549)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16494
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16494
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             669..1556
                     /locus_tag="ctg174_16"
                     /transl_table=11
                     /translation="MNNIIVGMGEALWDVLPEGKKIGGAPANFAYHVSQFGFDSRVVSA
                     VGKDELGDEILNVFNEKKLKTQIEQVDYPTGTVQVTLDNEGVPCYEIKEGVAWDNIPFT
                     DELKRLALSTRAVCFGSLAQRNEVSRATINRFLDTMPDIDGQLKIFDINLRQDFYTKEV
                     LRESFRRCNILKINDEELVTISRMFGYPGIDLQDKCWILLAKYNLKMLILTCGINGSYV
                     FTPGVVSFQETPRVPVADTVGAGDSFTAAFCASILNGKPVPEAHKLAVEVSAYVCTQSG
                     AMPELPQVLKDRLM"
     CDS             1763..2881
                     /locus_tag="ctg174_17"
                     /transl_table=11
                     /translation="MKHVSILFRSKCWNVFLLLCIALPSLAQKEFKIDQVSVVNVGDGR
                     FLYRDLMTEKPLNGEHRIIDGYHSAYILASFKDGFYDGKYEEHLDNILINEGVYKDGRK
                     NGLFKIYSKFDGKLKEEKSYKEGKLNGTSKTFFTDGKIESEKNYRMGKEDGKHLSYDYD
                     GTLRMDHNYKDGKQVGKQYTFMKGTYELYETVYYNNEGLKDGEYSSIFTFGAPHVLGSY
                     KNGQKNGRWTEIAESGDTIVIETYLNGKEEGLHVSYSGETGMRTKEYYLKNDRKDGIYR
                     EYDLKNGELKYEATYQFGRLHGKARQLVVDNRFDYWETSTYVNGRQNGPFESRYVKNNK
                     LRECGEYKNGHRVGRWKLYTIDGKLEREWDEN"
     CDS             3219..3374
                     /locus_tag="ctg174_18"
                     /transl_table=11
                     /translation="LFSIVHLGHRKKYEKNENDGIYKVDSSLALSSWHDGLSAGHTPLP
                     YRGGAM"
     CDS             3361..6099
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 61.6; E-value: 2.7e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg174_19"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.3e-19, bitscore:
                     61.6, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VAQCSDDSWRHKMNDEILREAMFYDGVSVEIRSAADDNRKQAEDV
                     HYFIDEGVDLLIISANEAAPMTPIVEEAYQKGIPVILVDRKILSDKYTAYIGADNYEIG
                     RAVGNYIASSLKGKGNVVELTGLGGSTPAMERHQGFMAAISNFPDIKLIDKADAAWERE
                     PAEVEMDSMLRRHPKIDAVYAHNDRIAPGAYQAAKKVGREKEMIFVGIDALPGKGNGLE
                     MVLDSVLNATFIYPTNGDKVMQLAMNILEKRPYPRETVMNTAVVDRTNAHVMQLQTTHI
                     SELDQKIETLNGRIGGYLSRVATQQVVMYGGLVILLLVAGLLLVVYKSLRAKNRLNKEL
                     SEQKKQLEEQRDKLEEQRDQLEEQRDKLEEQRDQLIQLSHQLEEATHAKLVFFTNISHD
                     FRTPLTLVADPVEHLLADHTLSGDQHRMLMLIQRNVNILLRLVNQILDFRKYENGKMEY
                     TPVQIDVLSSFEGWNESFLAAARKKHIHFSFDNMPDTDYHTLADMEKLERIYFNLLSNA
                     FKFTPENGKITVRLSSLTKEDTRWIRFTVANTGSMISAEHIRSIFDRFYKIDMHHAGSG
                     IGLALVKAFVELHKGTISVESDEKQGTVFTVDLPVQTCETILAEDSLKSSISAVPLNPA
                     SPGSPASSDLNGTLAAEEEELEKGYDSSKPSVLVIDDNADIRSYVRGLLHTDYTVIEAA
                     DGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPVILLTACSLDEQRI
                     QGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEK
                     FKALIEAKMGDSNLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELLRIARLKKAASLLA
                     SSDMTVAEIGYEVGFSSPSYFTKCYREQFGESPTDLLKRKG"
     CDS             6276..6614
                     /locus_tag="ctg174_20"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVAREIPVGKVSTYGGIAALLGMPQ
                     CSRMVGRALKQIPDDLSVPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVSE"
     CDS             complement(6744..6881)
                     /locus_tag="ctg174_21"
                     /transl_table=11
                     /translation="LFSTAAFLILTYDKQVECSHGSVMSHDNMTVRRFLNGLKKTDRVV
                     "
     CDS             6914..8140
                     /locus_tag="ctg174_22"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGHEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTAGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSRQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETHEFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             8137..8961
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.5; E-value: 8.7e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg174_23"
                     /sec_met_domain="BPD_transp_1 (E-value: 4.2e-29, bitscore:
                     92.5, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMVHFSTFFDAVNAGIGSFIIGFQHVLFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSPRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             8982..9848
                     /locus_tag="ctg174_24"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAMLLLASCTNSGLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFLG
                     EVYGEARVGLVVPQYVTIQSISELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRQLVDSW
                     IPKSENK"
     CDS             complement(10001..13549)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg174_25"
                     /sec_met_domain="PFOR_II (E-value: 1.7e-18, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.9e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.7e-31, bitscore: 100.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.7e-12, bitscore:
                     37.3, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 6.9e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 1.1e-08, bitscore: 26.0,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.3e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 4.2e-25, bitscore: 78.4,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDYLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDNPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     EQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTAKYEKRGVAAFVPEWNPENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAQAENWTYCAENVKTKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIAADCTPAEVKELFAEWINNMLDADKTKE
                     LAAKIIPVVEANKDKCNHCKQIAELQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGAE"
     CDS             complement(13582..14436)
                     /locus_tag="ctg174_26"
                     /transl_table=11
                     /translation="MCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREF
                     LNLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSEN
                     LLKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVM
                     NYIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFANSL
                     WKDHKVHKGDKNVSFMVDEVMPFKICQEGAKIKNNPNVTYALHKAEIGRGNQIPLWMFG
                     FLY"
     CDS             14461..14754
                     /locus_tag="ctg174_27"
                     /transl_table=11
                     /translation="MFEHLVDQQYFSATFLKFVGEVYNAVAREIEVVHVDEQTGTVVPE
                     FLFGVLEKESGFSYATCPFDTNQAVAPVDLVHKIAANGGIGVLNEVGVCAVE"
     CDS             14893..16125
                     /locus_tag="ctg174_28"
                     /transl_table=11
                     /translation="LQNKVLNSFEMTKKALYIFNPEHDLALASGETNYMAPASARRMAS
                     ELALLPMWYAEEGSAVLASSAYNLDYLKQMQELLGVSIHLMTEPELAVGPDLDIRPWGW
                     DVALRKRLLGLGVDEALLPSMEQLNGLREYSHRSKAVSLLPELQLNEYFCGESYYLKAL
                     EEWKTFVEERECCLLKAPLSGSGKGLNWCKGIFTPFISGWCTRVAASQGGIIAEPIYNK
                     VEDFAMEFYSDGTGEVTFMGYSLFHTGKSGMYEGNRLLSNEAIWKQLSQYVPSKVLTDL
                     ENCLKYRLSALVGTVYKGYLGVDMMICRFPENEKPVFRIHPCVEINLRMNMGVVARFLY
                     DHYVHPGSIGRFVIDYHPSEGEALQEHERMSATYPLKIREGRVYSGYLPLVPVHRRSCY
                     RAWIWVTPDNI"
     CDS             complement(16136..16402)
                     /locus_tag="ctg174_29"
                     /transl_table=11
                     /translation="VVFYIVFKLMGQFTDAEVRSARGRADAVVKTPKYIYVFEFKLHDT
                     AEAALKQIDDKGYLIPYQADGREVIKIGVEFSAEKRNISRWLV"
     CDS             16403..16492
                     /locus_tag="ctg174_30"
                     /transl_table=11
                     /translation="LVVTLCLLVQFVVEIGKEGLQAGEKGIVVS"
ORIGIN
        1 gccgtcattg ctatcctgtt gctcaatgtc acacagatta aagaggaaaa agaagaaggt
       61 aaaccgtcta ctttcggaca atgtctcgct ttgcttggca aaccgtttat cctgctttct
      121 ttcatcggta tcatgtgtca cgttggaatt gatgtgggaa caaataccac tgcccccaag
      181 attttgatgg aacgtctcgg catgggcctt gatgatgcgg cttttgcaac aagcctttat
      241 ttcatcttcc gtacggcagg ctgcttcctc ggttctttca ttttacgtaa gatgtcaccg
      301 aagtctttct tcggcattag cgttgtgatg atgctgatag cgatggcagg tttgtttata
      361 ttccatgaca agacaatgat ttatgtatgc atcggtctga ttggtttcgg caactccaat
      421 gtgttttccg tagtcttctc gcaggcattg ctttacctgc cgggtaagaa aaatgaagtt
      481 tccggtctga tgattatggg actgttcggc ggcacggtat ttccgttggc tatgggagta
      541 gcatccgatg ccatgggaca gagtggggca gtagccgtaa tgacagtggg cgtgctttat
      601 ctcttgttct atacgttccg tattaaaaaa taattttata actttggaaa caataaaatc
      661 cgtagatcat gaataatata atcgtaggaa tgggcgaggc actttgggat gtgttgcccg
      721 aaggaaagaa aataggtggt gctccggcaa actttgccta tcatgtatca cagtttggtt
      781 ttgacagtcg cgtggtgagt gccgtgggca aggatgagtt gggagatgag attctgaacg
      841 tattcaacga gaagaaactg aaaacgcaga ttgaacaagt ggattatcct accggtacgg
      901 tacaggtgac actggataac gagggggtgc cttgttacga aatcaaagaa ggtgtggcat
      961 gggataacat accttttacg gatgaactga aacgtttggc attgagtacg cgtgccgttt
     1021 gcttcggttc cctggctcaa cgtaatgaag tgagccgtgc cactatcaac cgttttctgg
     1081 atacgatgcc cgacatagac ggacaactga aaatctttga tattaatctc cgccaggact
     1141 tctacaccaa agaggtattg cgcgaatctt tccgccgttg caacattctg aagataaacg
     1201 acgaagaact ggtgaccatc agccgtatgt ttggctatcc cggcatcgac ttacaggaca
     1261 aatgctggat tctgttggca aaatacaacc tgaagatgtt gattctgact tgcggaatta
     1321 atggcagtta tgtgtttact ccgggtgttg tctctttcca ggagacgccg agagttccgg
     1381 ttgccgatac ggtgggggca ggtgattctt ttacggctgc tttctgtgct tccattttga
     1441 atggaaaacc ggttcccgaa gctcacaaac ttgccgttga agtttctgct tatgtctgca
     1501 cgcaaagcgg tgcaatgccc gaacttccgc aggttttgaa agacaggctg atgtaatttc
     1561 tctattgatg taaatgtagg gacgaaaaga atccaaaagt gaaaatcctt cttactacgg
     1621 tatgttgtag taaggaggat ttttttaatt caaatctttt cggatatcac ctcttttctt
     1681 ctctttttat tgttagattt ttagctaatt gtatatcttt gcacgattca caagataata
     1741 actaaaaaga gaatgtcaca ttatgaaaca cgtttctatt ttattccgct cgaaatgctg
     1801 gaatgtattt ttgcttctat gcatagccct tccctcatta gcacaaaaag agtttaaaat
     1861 cgatcaggta tctgtcgtta atgtaggcga cggaagattc ttgtaccgag acttgatgac
     1921 ggaaaaaccg ctcaacggcg aacatcgtat cattgacggt tatcactctg cgtatatact
     1981 ggcctctttt aaagatggtt tttatgatgg caaatatgaa gagcatttgg ataacattct
     2041 gataaatgaa ggcgtctaca aagatggacg gaagaatggc ttatttaaaa tctattctaa
     2101 gtttgacggt aaactgaaag aagaaaagtc ttataaggaa ggaaagttga acggtacgag
     2161 caaaacgttc tttactgacg gaaaaataga aagtgagaaa aactaccgga tgggcaagga
     2221 ggatggaaaa catttgtcgt atgattatga cggaactctg cggatggacc ataattataa
     2281 ggatggtaaa caagtaggga aacaatatac tttcatgaag ggtacttatg aactatacga
     2341 aacggtttat tataataacg aagggttgaa ggatggagaa tattcgtcca tctttacttt
     2401 tggagctcct catgtattgg gtagttacaa gaatgggcag aagaacggtc gttggacaga
     2461 gattgcagag agtggcgata ccattgtaat tgaaacttat ctgaatggaa aagaagaagg
     2521 cctgcacgtt tcatacagtg gtgagacagg gatgcgtacc aaagaatatt atctgaaaaa
     2581 tgaccgcaag gacggaatct atcgtgaata tgacttgaaa aatggcgaat tgaagtacga
     2641 ggcaacctat cagtttggca gactgcacgg aaaagcacgc cagttagtgg tggacaatcg
     2701 ctttgattat tgggaaactt ctacatacgt caacggacgg caaaacggtc cttttgaatc
     2761 tcgttatgtg aagaataaca agctccgcga atgtggagaa tataagaacg gtcaccgggt
     2821 aggacgttgg aaactttata ccattgatgg caaactggaa agggaatggg atgaaaacta
     2881 ggtcttatca actgtcatat aggttgtagg tgttatacag agtgcaaggc gtagccgtac
     2941 agacataaaa aaaggagcaa cgccttgctc caacctttgt taaccttaaa tctaatacta
     3001 tgaaaaacac attgcaaaga tacggacttc tgttaaatct gcaaataatc caaataaaaa
     3061 gagatgtttt ataacattta ttgagtgttt gtcttacgct ttatactttt gttaatagtt
     3121 tccggttgaa tattgggaac tgttttgcat ttctttggag ggtaatgatg agaataattg
     3181 ggtgatagat agcatactca cagttttatt tcttattttt gttctcaatc gtccatttgg
     3241 gtcatagaaa gaaatacgaa aaaaatgaga atgatgggat atacaaagtg gatagcagtc
     3301 ttgctctgtc ttcttggcat gacggcttgt cggcaggaca cacaccgctt ccgtatcggg
     3361 gtggcgcaat gtagtgatga ctcctggcgg cataagatga atgatgaaat tcttcgcgaa
     3421 gcaatgttct acgatggggt atcggttgaa atccggtcgg ctgcggatga taatcgcaaa
     3481 caggcggagg acgttcatta ttttatagat gaaggggttg acttattgat tatttctgcc
     3541 aacgaagcgg cccccatgac tccgattgta gaggaagcct atcaaaaggg aatacctgtc
     3601 atcctggtag accggaagat tctttctgat aaatatactg cctatatcgg tgccgacaat
     3661 tatgaaatag gacgtgcggt aggcaattat attgcgtcaa gcctgaaagg aaaagggaat
     3721 gtggtggaac ttactggact gggtggctca actcctgcca tggaacgcca tcaaggattt
     3781 atggctgcta tcagtaactt tccggatatc aaactgattg ataaagcgga tgctgcgtgg
     3841 gagcgtgaac cggcggaagt ggaaatggat agtatgctcc gtcggcatcc gaagatagac
     3901 gccgtgtatg cgcataatga ccgtatcgct ccgggagctt atcaggctgc aaagaaagtg
     3961 ggacgggaga aggaaatgat ttttgtcggt atcgatgctc tccccggcaa aggcaacgga
     4021 ttggaaatgg tgctcgacag tgtgttgaat gctactttta tttatccgac caatggcgac
     4081 aaagtgatgc aactggcaat gaatatcctt gagaaaaggc cttatccccg ggaaacggtc
     4141 atgaacactg cggtggtcga ccgtacgaat gcgcatgtca tgcaacttca gacaactcac
     4201 atctcggaac tggatcagaa gattgaaaca ttgaacggac gtatcggcgg atatctgtct
     4261 cgggttgcta cacagcaggt ggtgatgtat ggcggtttgg ttattcttct attggtggca
     4321 ggcttattat tggtagtcta taaatctctc cgtgctaaaa atcgtctgaa taaggaactt
     4381 tccgagcaga agaaacagct ggaagagcaa cgggacaagt tagaggaaca acgtgaccaa
     4441 ttagaagaac agcgggacaa actggaagag caacgggatc agctcatcca gctttctcat
     4501 caactggaag aggcaacgca tgccaaactg gtgttcttca caaatatatc tcacgatttc
     4561 cgtactccgc ttacattggt tgccgatccg gtagaacatt tattggccga tcatacacta
     4621 agtggagatc agcatcgaat gttgatgctg attcaacgaa acgtgaatat cctcttacgt
     4681 cttgtcaatc agattctgga tttccgtaaa tacgagaacg gtaagatgga atatacacct
     4741 gttcagatag atgttctttc ctcttttgag ggctggaacg aatcattcct tgcagcggcc
     4801 cggaagaaac acattcattt ctcttttgat aatatgccgg atacggatta ccatacattg
     4861 gcggatatgg aaaagttgga acgtatttat tttaatctgc tttccaacgc gttcaagttc
     4921 acaccggaaa atggaaagat aacggttcgt ttatcttcct taacgaaaga ggatactcgc
     4981 tggattcgtt ttactgttgc caataccggt tcaatgattt ccgccgaaca tattcggagc
     5041 attttcgatc gtttttataa aatagacatg caccatgccg gttcgggaat cgggcttgca
     5101 ttggtcaaag ctttcgttga attgcataaa ggtacaattt ctgtggaaag tgatgaaaag
     5161 cagggcactg tttttaccgt tgatttaccg gtacagactt gtgaaactat tctggccgaa
     5221 gattctctaa agtcatcaat ctctgcagtt cctttaaatc ctgcttctcc cggatctccc
     5281 gcctcttccg acctgaatgg aactttagct gccgaagaag aggaactgga aaaaggctat
     5341 gattcttcca aaccttccgt tttggtaatt gatgataatg cagatatccg ttcgtatgta
     5401 cgcggattac tccataccga ttatactgta attgaagcag cagacggttc ggagggcatc
     5461 cgcaaagcaa tgaaatatgt cccggacttg ataatctctg atgtgatgat gcctggtatt
     5521 gatggaatag agtgttgtcg tcggctgaaa agcgaactgc aaacctgcca tatccctgtc
     5581 atcttattga cagcctgttc tttggatgaa caacggattc agggatatga cggaggtgcg
     5641 gattcttata tctccaagcc cttcagttcg caattgctgt tggcacgcgt tcgtaatctg
     5701 atagattcac atcgccgcct gaaacaattc tttggtgacg gacaaacgtt ggcgaaagag
     5761 gatgtctgtg atatggataa agattttgtg gaaaaattca aggctttgat tgaagcaaag
     5821 atgggagact caaatttgaa tgtagaagat ttgggtaagg atatgggatt aagtcgtgtg
     5881 cagctctatc gcaaaataaa atccttgact aattattctc cgaatgaatt gcttcgtatc
     5941 gctcgtttaa agaaagctgc ttccttgctt gcttcgtcgg atatgacagt ggcagagatt
     6001 ggttatgaag tcggtttcag ctctccttct tattttacca aatgttatag agagcagttt
     6061 ggagaaagtc cgacagattt gctgaagagg aaaggataga acttatttct ttgattgaga
     6121 tatggtaaat caagcatata agcgtatgtt attgtgtttt aggtacaaat ttcccaaaca
     6181 tgaaacaggt gtttgttggg tactgttgtt cttattattt gcaaattctc ttctttttat
     6241 ctagctttgg aaatgaaata aataaagtct aaacgatgaa agattataaa gtagacaaag
     6301 cgagtctctc cgcatccttt tgtcaagagg tgtatcaggt tgctcgggaa attccggtag
     6361 gtaaagtttc tacctatggg ggaattgccg cattattggg aatgcctcaa tgttcccgta
     6421 tggtggggcg tgctttgaaa cagattccgg atgatttatc tgtgccttgt caccgggttg
     6481 tcaatgcatc gggacgcctt gttccggggt ggacagagca gaaacaactc ttgttggaag
     6541 aagggatctc tttcaagcaa aatggatgcg tagacttgaa aaagcatctt tggaattact
     6601 ccgtatctga atgaaatttg catatttaat ctattttcct tacctttgtg ccaacaatat
     6661 gcaagaacag actgttattt atttatgaaa atactgtttt ctactgttca ttgagaggat
     6721 aatcttatca aattctattc cttttaaact actctgtctg ttttttttaa accatttaaa
     6781 aaacgtcgga ccgtcatgtt atcatgtgac atgactgaac catgcgaaca ttcaacttgt
     6841 ttatcgtaag tgagaataag gaatgcggca gttgaaaaca aaacaaatat tataatctaa
     6901 accaatatat tatatgagta aaatagaaat aaaggatttg taccttatct ttggtcacga
     6961 gaagcagaaa gcactcaaga tgttgaaaaa agataagagt aaagaggaaa ttctgaaaga
     7021 taccggttgt acggtaggag tgaaagatgc caatctttca attaatgaag gagagttttt
     7081 tgtgataatg ggactttcgg gaagtggaaa atcgacatta ctgcgttgta tcaatcgtct
     7141 gatacgtcct actgccggac aagtacttgt aaacggagta gatatatcta aaatatccga
     7201 aaaagagtta ttgcaagttc gccggaaaga gttggcgatg gttttccaga atttcggtct
     7261 gttacctcac cgttccgtat tgagcaatat cgcgttcggc ctcgaacttc agggagtgaa
     7321 gaaagaggaa cgtgagaaga aagcgatgga aagtatgaag cttgtcggat tgaaaggata
     7381 tgaaaatcag atggtgggcg agctttccgg tggaatgcaa cagcgtgtcg gactggcccg
     7441 tgctctggct aataatcccg aagtgctttt aatggatgag gctttctctg cgctcgatcc
     7501 tctgattcgt gtgcaaatgc aggatgaact gctggctttg cagtcgaaga tgaaaaaaac
     7561 aattgtcttt attacccatg acttgagtga agcgattaaa ctgggcgacc gtattgccat
     7621 tatgaaagac ggagaggtgg tgcaggtagg tacttcagaa gaaatactga ccgaaccggc
     7681 taacgattat gtagcccgtt ttgttgaaaa cgtggacagg agtaaaatta tcaccgcttc
     7741 ttctttaatg attgacaaac cactggtggc ccgtctgaag aaagagggac ctgaagtatt
     7801 gattcgtaag atgcgtgcga agaatatcac cgtattacct gtcatagacg ccgatgataa
     7861 actggtcgga gaagtacgtc tgaacgacct gcttaagtta cgtagcagac aggaaaaatc
     7921 cattgaaacg attgtgcgta cagaagtaca ttctgtattg gaggatacag tgttggagga
     7981 tatacttcct ttaatgacaa agagcaattc gccggtatgg gtgattgatg agacgcatga
     8041 gtttttagga acaatcccgc tttcctcctt aatcatcgaa gtgacgggga aagataaaga
     8101 agaaataaac gaaataattc aaaacgcaat agatttatga taaatatagg acaatatata
     8161 gagatggcca tcaattggat gatggtacat ttttccactt tctttgatgc cgtgaatgca
     8221 ggcatcggta gttttattat aggattccaa cacgtacttt ttggaatacc tttttatata
     8281 accattctag tgcttgctgc actcgcatgg atgaaggcag gacgtggtac ggcaattttc
     8341 accgcattag gattattact gatttatgga atgggatttt gggaggctac tatgcaaacc
     8401 ctggctctcg ttttttcatc tacctgtctg gctctgattg ttggtgtacc tttaggagtg
     8461 tggacggcaa acagtccgcg tgcagagaaa atacttcgtc ctgttctcga cttgatgcag
     8521 acgatgcctg cttttgttta tctgattcct gccgttttgt ttttcggatt gggagcagtg
     8581 ccgggagtgt ttgccaccat tatctttgct atgcctcctg tggtccgcct tactggattg
     8641 ggaattcggc aagttcctaa aaatgtagtg gaagcttccc gttcgttcgg ggctacccgt
     8701 tggcagttat tgtataaagt gcagcttcct ttggcgttgc caaccatcct gacaggtgtc
     8761 aatcagacaa taatgatgtc gctttctatg gttgtcattg ctgccatgat tgctgccggt
     8821 ggtctgggag aaattgtatt gaaaggtatt acccaaatga aaatcggact tgggtttgaa
     8881 ggtggtatcg cagttgttat tttagctatc atcttagacc gtatcacaca aggaatggca
     8941 ggacgaaaaa ataagaacta aacggaaagg ataaaatacg tatgagaata tataaaatag
     9001 taggaatagt attgtcagct atgcttttgc tagcttcctg tactaattca ggcttagaga
     9061 aaaagaaagt aaaaatagcc tatgccaatt ggctggaagg tattgccatg agtcatttgg
     9121 ccaaggtggt attggaagag catggatatg aggttgaatt gcaaaatgct gatcttgccc
     9181 ctatttttgt atctatgtca ggaaagaaat ctgatgtctt tctggatgca tggttaccaa
     9241 taacgatgaa agattatatg gatcagtatg gagacagcat cgaatttttg ggggaggtat
     9301 atggagaagc ccgtgtagga ctggttgttc ctcaatatgt tacgatccag tctattagtg
     9361 agctggaagc taataaagac cgtttctctt ctgaaatagt aggaattgat gcgggagcag
     9421 ggataatgaa gacgaccgat aaggccattg ctgcttacgg acttgatggg tataccctca
     9481 tgacttcaag tagttccacc atgctggctt ctttgaaaaa agcgatggac aaaggagaat
     9541 ggattgtcat tacggggtgg acaccgcatt ggatgttcga ccagtttgac ttgaaattct
     9601 tggatgatcc gaagaaagta tatggagact tggaagaaat acatgctatt gcatggaaag
     9661 gattcagtga gaaagatccg tttgctgccg aattctttgg caacatcaaa ctaacgacag
     9721 aagaacttag ctcttttatg acagctatga aggatgcccg gatggatgaa gaagaaatag
     9781 cccgtaaatg gagggatgaa catcggcagt tggtggatag ttggattccg aagtcagaga
     9841 ataaatagat tggagcattg ttatttttaa ttttaaatat aaaatagaca tgaactctag
     9901 tgggaaaaag ggagtattgt ttatgttaga cagagttcat acaataaaaa aacggtaatc
     9961 ttctacaaga ttaccgtttt atatttatag ggtattacta ttattcagca ccccagtttt
    10021 ctctagccaa acgtttgtag ctgttgtaac gccatttagc gttttcttca gcagctttga
    10081 acagttcttc agcttcagca ggatattgtt tcattacaga agcgtaacga acttcaccct
    10141 tcaagaaacc ttggaaatct tcccagttcg gttctttgct atccaattgg aatgggttct
    10201 tgccttcttc ttccaaagcc gggttgtaac gccacaagtg ccagtaaccg cacttaacag
    10261 ctttttcttc ttcttcttgg ctcttaccca tacctgcttt cagaccgtgg ttgatacatg
    10321 gagcataagc gataatcaaa gatggtcccg gatatgcttc agcttcacgg atagctttca
    10381 gagtttgagc ttggtcagca cccatagcga tctgtgcaac atatacataa ccgtaagtag
    10441 tagccatcag accgaggtct ttcttacgta cgcgcttacc agcagcagcg aacttagcga
    10501 tagcacctac cggagtagct ttagaagact gaccacctgt gttagagtaa acttcagtat
    10561 ccagaacgag gatgttaacg tccttaccgg aagcgattac atggtcaaga ccaccgtaac
    10621 cgatatcgta agaagcaccg tcaccaccaa tgatccactg gctgcgtttt acaagatatt
    10681 gttgcagttc agcgatttgt ttgcagtggt tacatttatc cttgttagct tcaacaaccg
    10741 gaatgatctt agcagccaat tccttagtct tgtccgcatc cagcatattg ttgatccatt
    10801 cagcgaacag ttcttttact tcagcaggag tgcaatcagc agcaatagcc tcgttcatca
    10861 ctttcacgag acgagcacgc atcttttcgt tagccagttc catacccaaa ccgaattcac
    10921 agaagtcttc gaacagtgag ttagcccaag caggaccgtg tccgttttcg tttgtagtat
    10981 acggagtaga aggaacagaa ccagagtaga tagaagaaca tccggtagcg ttagcaacca
    11041 tttcacggtc accgaacaat tgagaaatca atttcacgta tggagtttca ccacaaccag
    11101 agcaagcgcc ggagaactca aacaacggag tagcgaactg tgagttcttc acgttagcct
    11161 tgatatcaac aagatgttgt ttagtcttca cgttttcagc acagtaagtc cagttttcag
    11221 cttgagccaa ttggctttcg aggtgtttca ttgtcaatgc tttgccaccc ttcttcggat
    11281 tacccggaca gatgtcagca cagttaccgc aacccagaca gtcgagaacg tccacctgga
    11341 tacggaatgt cataccgtcg aatgctttac ctacagcttt cagttgttcg aacttagcac
    11401 ccttctgctc ttcagcgtcg agtacgaacg gacggataga agcgtgagga caaacgtatg
    11461 cacacttgtt acactggata cagttttccg gattccattc aggaacgaat gcagctacac
    11521 cacgtttttc gtatttagca gtaccttgat accaagtacc gtcttcgata cccttgaatg
    11581 cagataccgg caacaagtca ccgtcttgtg cattgatcgg acgaactact tcgttgatga
    11641 atgcaggatc gttgttttca gcttttgcgt catccggaag gttagcccaa gcaggatcaa
    11701 cagccaaagt cttgtattca ccaccacggt caacggcagc atagttcttg ttaacaacgt
    11761 cttcaccctt cttgccgtaa gacttaacga tgaatttctt catctgctca acagcttgtt
    11821 ctacaggaat aacgcctgtg atacggaaga atgcagattg aaggattgtg ttggtacggt
    11881 tacccaaacc aatttccagt gcaatctgtg ttgcgttgat atagtataca gaaatgttgt
    11941 tctgtgcaaa atatttctta accttgttag gcaggttctt agccagttct tcaccttccc
    12001 agattgtgtt cagcaagaaa gaaccgttct tacgcaaacc acgagttaca tcgtacatgt
    12061 gcaggtaagc ctgaacgtga caagcaacga agttcggagt gtttaccaaa taagtagaac
    12121 ggatcggatt atcaccgaaa cgcaagtgag aacaagtgaa gccacctgac ttcttagagt
    12181 cataagagaa gtaagcctgg cagtgtttgt cagtgttatc accgataatc tttacagagt
    12241 tcttgttagc acctactgta ccgtcagcac ccaaaccgta gaatttagct tcgaacatac
    12301 cttcgccgcc taaagcgatt tcttcttttt gaggaagaga agtgaaagta acgtcgtcta
    12361 cgataccgat agtgaagtgg ttcttcggca ttggcatagc caagttttcg aatactgaaa
    12421 ggatttgagc aggagtagta tcttttgaac ccaaaccgta gcgaccgcca acgataaccg
    12481 gagcattttc tgcaccgtag aagcagtctt taacgtcaag gtaaagaggt tcgccgttag
    12541 cacccggttc tttagtacgg tcaagaactg cgatagtctt agcagtctta ggtacagcag
    12601 ccaggaagtg tttagcagag aacggacgat acaggtgtac ggcaaccata cccacttttt
    12661 cgccgtttgc taccaggtag tcgatagctt cgcgggcagc ttctgttaca gaacccatag
    12721 cgataattac gcgttctgca tcttctgcac catagtaatc gaacaaaccg tatttacgac
    12781 ctgtgatctt agaaatttca ttcatgtatt cttctacgat agcaggaact gcttcatagt
    12841 agttgttgca tgattcacga tgttggaaga aatggtcagg attttcagcc ataccacgag
    12901 ctaccggttt catcgggttc agtgcgcggg cacggaattc agccaaagct tcctggtcga
    12961 tcagcggagc aagatcatca ttttccaaca tttcaatctt ttggatttcg tgagatgtac
    13021 ggaaaccatc gaagaagttc atgaacggaa cgcgagattt gatggtagcc aagtgagcaa
    13081 caccagccaa atccataact tcctgtacag agccttcagc caacatagca aagccagtct
    13141 gacgagctga cattacgtct tggtggtcac cgaagataca caatgcgtga gaagccaatg
    13201 tacgagcaga tacatggaat acgcaaggca agaactcacc ggcaattttg tacatgttag
    13261 ggatcatcag gagaagaccc tgggaagcag tgtaagtagt agtcaacgca ccagcctgaa
    13321 gagaaccgtg aactgcaccg gcagcaccac cttcagattg catttcctgt actaatactg
    13381 tttcgccgaa gatgttctta cgtcctgcgg cagcccattc gtctacgtac tcagccatag
    13441 tcgaagaagg agtgatgggg tagatagctg ctacttcaga gaacatatac gagatatgcg
    13501 ctgcagcctg gttaccatca caagtgatga atttcttctg tttagtcata actaaattaa
    13561 atatttaagt aaataaatct tttaatataa aaagccgaac atccagagag gtatctggtt
    13621 gccccgacct atttcagcct tatgcaacgc gtatgttaca ttcggattgt tcttgatctt
    13681 tgcgccttcc tggcaaattt tgaacggcat tacttcgtct accataaaag agacgttttt
    13741 atctccttta tgtaccttat ggtctttcca taaagaattt gcaaagaatg tgtcgagcac
    13801 atcctgctct tccactttca ccggatagat ggaatacatc aggttggagt tgtgcatcat
    13861 tatctttgaa ggttttttag ggaattcttc ccctttcgga taaaccagat taatgagtcg
    13921 cgcatctgcc agatacttga tatagttcat caccgtggcg cgagatgtct gtatgtcgct
    13981 tgccagttgg ctcacatttg gagctttcgg cccgtcgaca gcgagcaaat atagcaattt
    14041 ttttatcttt gaaagatatt tcagttcaat ttgtttgatg agaagtatat ctacttccac
    14101 catcatgttc atcgttttca gcagattctc cgaaaagtta cgtttttcaa ggaagaacgg
    14161 atagaatccg tggtgcagat aatcctgaaa ataatccaac ggacggactt tggagagtac
    14221 tcctttggca atctgttcgt gagtgctaag aatttcttcg aggctatatg ccctgaattt
    14281 catgcctgtt tgcaagttta ggaattcacg gaaagagaat ccacgcaggt tatagctctt
    14341 ggcgatatca cgtaattcaa gattttcttc tttcagtcgc atcacggacg agccggtgaa
    14401 gacaattttc aggttaggaa aacggtcgta acacatgcgt aactctttgc tccattccgg
    14461 atgtttgaac acctggtcga tcaacaatac ttttccgcca cgtttctgaa attcgttggc
    14521 gaagtctaca atgctgtggc ccgagaaata gaagttgttc atgttgatga acagacagga
    14581 acggtcgttc ccgaatttct ctttggcgta ttggagaagg aaagtggttt ttcctacgcc
    14641 acgtgtccct ttgataccaa tcaggcggtc gctccagtcg atctcgtcca taagatcgcg
    14701 gcgaacgggg gcattggtgt gctcaacgag gtaggcgtgt gtgcggtaga atgattccat
    14761 ttcagttctt tgtttttcgg gtggcaaata tactgctttt tttaggattt gcaaagtaga
    14821 gatggcaaaa ttgtgtgttt aattccaact ttctgtttat tgtagtcatt cctgactatt
    14881 tcctgtatat atttgcagaa taaagttttg aattcatttg aaatgacaaa aaaggctctt
    14941 tatatattca atccggaaca tgacttggcg ttggccagcg gtgaaactaa ttatatggct
    15001 ccagcttcgg ccagacgtat ggcttccgag ttggctttgc ttccgatgtg gtatgcagag
    15061 gaggggagtg ctgtattagc ttcttccgct tataatctgg attatttgaa gcaaatgcag
    15121 gaattgctgg gagtttcgat tcatttgatg actgaaccgg aacttgctgt cggaccggat
    15181 ttggatattc gtccttgggg gtgggatgta gctttgcgga aacggctttt agggctgggc
    15241 gtggacgaag ccctgcttcc ttctatggag caattaaacg gtttgcggga atactcccat
    15301 cgttctaaag ccgtctcgtt acttccggaa ttacaactga atgaatattt ctgcggagaa
    15361 tcttattatt tgaaggcact ggaagaatgg aaaacttttg tggaagagcg ggaatgctgc
    15421 ctgttgaaag ctccgctttc gggaagcggt aaaggcttga actggtgtaa aggcatattt
    15481 actcctttta tttccggttg gtgtacgcgt gtggctgctt cgcagggtgg aatcattgcg
    15541 gaacctatat ataataaggt agaggatttt gccatggagt tttattccga tggtacaggt
    15601 gaagtgacat ttatgggata ttccctcttc cataccggaa agagtgggat gtatgaaggg
    15661 aatcgtttgc tttctaatga ggcaatctgg aaacaacttt cgcaatatgt cccttcaaag
    15721 gttctgacgg atttggagaa ctgcttgaaa tataggcttt ctgcgttggt aggaaccgtt
    15781 tataaaggtt atcttggagt tgatatgatg atttgtcggt ttccggaaaa tgaaaagccg
    15841 gtttttcgga ttcatccctg tgtggaaatc aatctgcgca tgaatatggg agttgttgcg
    15901 cgttttttat atgaccatta tgtacatcca ggttcaatag ggcgttttgt gattgattat
    15961 catccttcgg aaggtgaagc cttgcaggaa catgaacgaa tgtccgcaac ttatccgttg
    16021 aaaatcaggg aaggtagagt gtactccggt tatttacctt tggttcctgt tcataggaga
    16081 agttgttatc gggcgtggat atgggtaact cctgataata tttaacttta tctgttcaca
    16141 ccagccagcg actgatattg cgtttttccg cactgaactc taccccgatc tttatcactt
    16201 cacgtccgtc tgcctgatac ggtatcagat agcctttatc gtcgatctgc ttcaatgccg
    16261 cttctgccgt gtcatgcagc ttgaattcga agacatagat atatttaggt gttttcacta
    16321 cggcatctgc acgaccgcgg gcgctgcgta cttcggcatc ggtgaactgt cccataagtt
    16381 tgaagacaat atagaaaacc acttggtagt gacgctctgt ctgctcgttc aattcgtagt
    16441 tgaaatcggc aaagaaggct tgcaggcggg tgagaaaggc atcgtagtct ccac
//
