LOCUS       c00022_gnlPro..        22103 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NLFBOJIL_42.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 09:18:08
            Original ID  :: gnl|Prokka|NLFBOJIL_42
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22103
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22103
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5580:12103]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5581..12103
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..22103
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22103
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(190..852)
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="MQSQFSTVEEALNQLVNGGYIILADNEDRENEGDLVALGENVNAD
                     TIYEMLNEANGLMCVPVSEDIAKHLAFKPMVEHSTDPHQTPFMVTTDGTLEATGVTTGV
                     SAFDRAATIRQIAKPTAQASDFNHPGHIQPLYAQPHGLRDRIGHTEAAIDLAYLAGKAP
                     VAVIIEVLKRDGTMARRDSLSVLANRVHVPFITINQIVEYLDVKGIDYAADLAKVNA"
     CDS             complement(1109..2284)
                     /locus_tag="ctg22_2"
                     /transl_table=11
                     /translation="MLEKTFYKSLLKHSFNIPVKIVFWDGSSVIYGDGTPEVTITFNEK
                     IPMRDITKNASIALGEAYMDKKIEIQGSIQELIESAYESADSFMRSSKFRKFLPKQGHS
                     EKESENDVQSHYDVGNDFYKLWLDDTLTYSCAYFTDGNHDDLTKAQVDKVHHILKKLDP
                     KPGKTLLDIGCGWGTLMLTAAKEYGLKVTGVTLSEEQYRFVKERIEKEGLQDVAEVKLV
                     DYRELGDQKWDYITSVGMFEHVGKENLGFYFKDIQGCLADDGVALIHGITRQQGGAYNG
                     WINKYIFPGGYVPGLEEMIGHIEENHMQIADIEMLRRHYQRTLEIWDMNFNEHRAQILD
                     MMGERFTRMWDLYLQACAASFESGNIDVIQYLITKGPSGKNLPMTRDYMTK"
     CDS             2454..3488
                     /locus_tag="ctg22_3"
                     /transl_table=11
                     /translation="MTNAWKHFIENVKLRRFTVLLLIIVVLWLMKSMMNLILFTFILTY
                     LVVSWVRLVQRWLPRMSTSLIVIVTYVLLIVLLYLGVTRYLPVLSRQVVKMVNSVVHFY
                     STHQATMIYRYVSHYISTATIMSQVRHGITIAVSTLTSIGAITVSFVMSLILSFFYTLE
                     LKQMNEFSHSFLDSDFGWFFQDIDYFGKKFVNTFGVVLEAQFFIAICNTVITTIGLLFM
                     RMPQIFALSLIVFIFSLVPVAGVIISTIPLAMVGYSVGGIRDVVYIIIMIIIIHTLEAY
                     VLNPKFMSSRTDLPIFYTFIVLLIGEHLFGTWGLIVGVPIFTFLLDVLGVKPIRGAKRI
                     KKEV"
     CDS             3726..5387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_4"
                     /sec_met_domain="FTHFS (E-value: 2.2e-260, bitscore: 855.3,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDIEIADKATLEPITEIAEKLGLSEDAIEQYGKYKAKIDLNVKP
                     LPDKKHKLILVTSINPTPAGEGKSTVLIGLGDALNQLNYQTTIAMREPSMGPVFGIKGG
                     ATGGGYSQVVPMEDINLNFTGDLHALTSANNTLAALIDNYIMRDNAMNLDPRRIIWKRV
                     EDVNDRALRNVVTGLGGPMAGVPRETGFNITAASELMAILCLSTSLHDLKERISRIVVG
                     YTYDKEPVTVGQLNFQDAITIILKDALKPNLVQTLDHTPTIVHGGPFANIAHGCNSVLA
                     TQTALNLSDYTVTEAGFGADLGGEKFLDIKQRVLGKHPDAIVIVATVRALEYNGGAKLA
                     DLNDENLDALKKGMANLNRHIKNMQLYGLPIVVAINHFVSDTDKEIQMIKDDCAKQNVE
                     AILTDAWAKGGKGTHDLANKVVELADSPSEFTHIYDVQVDDLQTKLEKIAKQIYGAKEV
                     SFSRKAQNQLKRFAKYGWNDLPVCIAKTQYSFTDDQKQLGAPTDFTFHIRELVPKIGAG
                     FVVALAGNMMTMPGLPKEPAAVNMTIDDNGKITGLF"
     CDS             5581..7260
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.4e-44, bitscore:
                     141.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEKLHGADVVIDSLRKHGVNLVFGIPGAKIDRLFEGLDGQDSED
                     APKLIVTRHEQNAAFMAQAYGRLTGKTGVAITTSGPGVGNLATGIMTANAEGDPMLAIG
                     GQVQRKDLHRATHQSTPSTEIMAPITQYSAEIQDPNNISEIMANAFEASQDARKGAAFV
                     SLPQDVDDAEVTEKPLPIYETPKMGPADPNDLQKLVELIKNSKMPVILVGQRGADEEIT
                     TALRKLLSDYLLPVVETYQAAGVVSRDLEQQSYFGRIGLFRNQVGDQLLQQSDLVIAVG
                     YDPIEYEPRNWNKEGNLRIVNLDTLPAQIDNHYTPIMQLVGNITTSLTELDKLLKGYEY
                     PLAATEQLAKYKQELDQDKKIQVPASNDASHPLAVVHAIQENVTDDMHVALDVGSHYIW
                     MARHFRCYQPRHLLISNGMQTLGVGLPWAMVAAMLYPEHKSVAVCGDGGFLFSGAELAT
                     AVQHHLNVVTIVWNDGGHYDMVKFQEEMKYSQAAGVKFGNVDIVKYAESFGATGLRVNK
                     PADLTKVISQAFNIDGPVVVDVPVDYSNNKELAANLIDSQLG"
     CDS             7316..7993
                     /locus_tag="ctg22_6"
                     /transl_table=11
                     /translation="MAGNFDGTITVGDLLKHGSMGIGTFTGLDGEVVILNNEVYQAVSS
                     GQVNHITDMDATMPFASVHFPAEQQDITLRNVNFAKLNNDFVKEHQLTNVFAFLQLSGE
                     FKHVKIRIAPKQEKPYPTLLDVAQHQPEFAADNIAGTIIGYYAPEIFGTITAAGWHLHF
                     ISDDRQFAGHLLAFDAPELTGSFEIFDNLEQHLPIHNQEFRASEVDMATLRDGIAKSEG
                     NAD"
     CDS             8895..9227
                     /locus_tag="ctg22_7"
                     /transl_table=11
                     /translation="LTVIPRERSKNILAYLHKHYAEKVTINDSATAVNISPKECIRSFK
                     KNIHQTPIEYLLNYRVEQAKKLLRHSELSITDIVLRAGFSTSAYFSKIFKERVGMTLRE
                     YRQRQG"
     CDS             complement(9229..10722)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_8"
                     /sec_met_domain="PALP (E-value: 2.6e-14, bitscore: 44.0,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYRSTQGDLSTILKSPTAILQGLSPDGGLYVPLHFPQPTYNLAT
                     LISLPYQQLAATILNWFFDEFTSDQLLKNANTAYGSQWDNRLIAPLTPKHASNYYLELF
                     HGPTLAFKDIALQMLPQLVSRAAQNTQLEKQIVILTATSGDTGTASMRGFSNQKDTQVI
                     VFYPAGGVSPVQLRQMLGQPGSNLHAIAIKGNFDDAQTSVKHIFNDQAFNDRLAQNNNC
                     FSSANSMNIGRLIPQIVYYFAAYGQLVHTGGIQLGEKVNFTVPTGNFGDILAGYYAKKL
                     GLPINKLLCASNENNVLTDFFKSGKYERRRNFYLTNSPAMDILVSSNLERLLFDLYDES
                     CVTVAKLMKQLATDGHYQVDSTVLNKLQEQFVAGFATPDEVEAEIKRVYLNDGYVIDPH
                     TAVASHVTHQYQQQSHDTTPTVIVSTASPYKFPETVYHALTNQKVSQSGIPALQQLHDL
                     LGDQLSAGVQALVDQTPRQEKVINPADMETLISKILNLK"
     CDS             10829..12103
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: Homoserine_dh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_9"
                     /sec_met_domain="Homoserine_dh (E-value: 2.7e-65, bitscore:
                     210.3, seeds: 932, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNIKLGLLGLGTVGSGVLQMVQQNADKILDVTGCKLTVKTALVR
                     NLGNYNKYADETSLTTDFDEILNDDEIKIVVELMGGIHPAKEYITTLLKNHKNVVTANK
                     DLIASYGPELMTVAHENHCDLMFEASVAGGIPILRTIANSFTADKVTEVKGIVNGTTNY
                     ILTQMSQRGWSYHQALAQAQQLGFAESDPTNDVTGKDAAYKMIILSQFAFGTQLDIKDI
                     AVEGIDRLNDADVQQAASFGYVIKLLGITKLVNNGVFVEVGPVLIPRDHPLATINNEFN
                     AVMVTAQAVGDTLFYGRGAGGLPTANSVLSDITTVTKNIILGTNGNLFNNYQQPYIPAK
                     LADIKYPYYLSLTLPDVPGQMLKLTQMMTDINASFREITQTKDGKIAHIAIITHRMSKE
                     QLQTLLTKVANDQSINLSAAYKVMG"
     CDS             12115..12975
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_10"
                     /sec_met_domain="GHMP_kinases_C (E-value: 5.5e-10,
                     bitscore: 30.4, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 5.1e-15,
                     bitscore: 46.4, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIQAPASSANLGPGFDSIGIAVSLYLKLEVLGPSDNWQVDHQLG
                     KLPYDETNMIVTTALSVAPDLPPQHLRVVSEIPIAHGLGSSSSAIVAGIELANQLKNLN
                     LSKEEKVEIASQIEGHPDNVAPTILGGLVVGTHINGHFSAIEAPLFPYAFAAYIPPYNL
                     KTADARAALPYQLEYSQAVHASAVANTFVASLFAKNYDVAFKLMEADRFHEPYRKELVP
                     ELDQIRELGKKHGALATYLSGAGPTVMTVIDNDNYGLFEQAVHAAGLKGKVVRLHPDVE
                     GVKLI"
     CDS             13129..13614
                     /locus_tag="ctg22_11"
                     /transl_table=11
                     /translation="MSDISVVMGSKSDWPTVKETCDILDEFGVSYEKNVISAHRMPNEM
                     FAFAQNAVDNGVKVIIACAGGAAHLPGMIAANTPLPVIGIPGQTKALGGMDSLLSIVQM
                     PAGIPVATTAIGKAGAKNAALLALQILGITDKHIQQQIIEYRQAMHDQAKESGQYLE"
     CDS             13577..14731
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hacid_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_12"
                     /sec_met_domain="Hacid_dh_C (E-value: 6.7e-10, bitscore:
                     29.4, seeds: 144, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 5.2e-13,
                     bitscore: 39.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKQKKVGSILNKFIPQGSTIGIIGGGQLGQMMALDAKQTGMKVI
                     ILDPTPNCPAGQVADEQIVAPYADTKAIEKLADKADVLTYEFENVDLNALEDVQDRVYL
                     PQGTNLLYTTKNRLREKNFLRQAGVKTAPFMAVHTSAELKDAVKKIGYPAVLKTSEGGY
                     DGHGQEVLRNKDDLDKCASILATGDCILEGWVPFNRECSVMVGRNEDGEITAFPVSENI
                     HHDEILHLSIVPARISSELQQKAQKIAVQIAQAINLRGILGVEMFVTDDGEIYINELAP
                     RPHNSGHYSIEACNFSQFAIHNRAICNWPLPQVELLKPVVMVNVLGQHVNGVRQQIQKK
                     ANWHFHDYGKAEVRHNRKMGHVTILTDDIEATLAEIDNAGIWGA"
     CDS             14803..16098
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_13"
                     /sec_met_domain="Lyase_1 (E-value: 5.9e-64, bitscore:
                     207.1, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDRYTSPKMKKIWSLETQYQCWLDVEIAADEAWSKLGHIPAEDV
                     EKIKKNAKFSVEGIAEIEAVTHHDVIAFTRDVSKSLGPERKWVHYGMTSTDVVDTAQGL
                     RLKKANDILRQDIDNFMDVLKELAEKYKYTVCMGRTHGIHAEPTTFGLKAARWYSEMKR
                     NKERFEHATKGVEAGKISGAVGTFAEIDPFVEEYVCKKLGLRPQEISTQVLPRDLHAEY
                     IATIALIGTSMEEMATEIRSLQRTEIHEVEEHFAKGQKGSSAMPHKRNPIGSENITGCA
                     RMLRGFMVPAYEDVSLWHERDISHSSAERMILPDATSLLDYMLRRFGRILKNLDVFPET
                     MKKNMDKTLGLIYSGRVLLKLVNSGMTREAAYDLIQPYTAKCWAEQIPFRPLLEDDPTI
                     QKQLTKEDLDDAFDYHWHLRHVDDIYKRLGLD"
     CDS             16322..17041
                     /locus_tag="ctg22_14"
                     /transl_table=11
                     /translation="MEKLLYTGKAKQMWQTEDPAVLRVVYLDQATALNGKKKDHFTGKG
                     KAANAISSLVFGYLMKQGIETHFIKKLSTNEDLVKKCEMFPLEFVTRNVIAGHFASRYG
                     LSEGEELPSPVEETFYKSDELNDPFINESATIALEIASKEELAQMWGICRKVNNLLKPL
                     FAKANLRLVDFKLEFGRLSDGKIILADEFSPDNCRLWDLTTMQHMDKDVYRRKLADLTQ
                     TYDEVLERLEAVMKEEA"
     CDS             17042..17290
                     /locus_tag="ctg22_15"
                     /transl_table=11
                     /translation="MVNVRIFVTYKQSVFDPQGETIKDAIHSLGHDEVTAVKVGKFFDV
                     TLDTNEDEVASAVKEIADQLLVNFNMETYTYQVMEEA"
     CDS             17291..17971
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_16"
                     /sec_met_domain="GATase (E-value: 3.4e-09, bitscore: 27.5,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAVVVFPGSNCDVDLYEALHSVCHADVEYVSHRQKSLAGFDAV
                     MLPGGFSYGDYLRAGAIARFTNIMPAIIKMANEGKPVFGTCNGFQILTEAGLLPGGLKR
                     NDSQRFVCKTVPLEVVNSHTLFTSHYQDHERIALPIAHADGSYYADEKTLDELEANNQI
                     VFRYATENPNGSLRNIAGITNKHGNVLGMMPHPERAVETILGSTDGLRLFESLLENGRI
                     KVEA"
     CDS             17975..20203
                     /locus_tag="ctg22_17"
                     /transl_table=11
                     /translation="MKQAMTPEEIKEKKPYLDWSLTEAEYDYIRTQLLGRLPNYTETGL
                     FSAMWSEHCSYKKSKPVLRLFPNKNERVLQGPGEGAGVVDIDDGQAVVFKAESHNHPTT
                     VEPYQGAATGVGGILRDIFSMGARPIASLDSLHFGELDNSTTRMKVTNTVRGIGDYGNC
                     MGIPTIAGETTFDPCYQGNILCNAMSVGLMDQKDIQQGRAAGIGNAVMYVGAKTGRDGI
                     HGATFASADFNDENTTQRSAVQVGNPFMEKLLLEACLDLIRNHPDWLVGIQDMGAAGIV
                     SSSAEMASEGKSGMELNLDLVPQREPGMSAYEIMLSESQERMLLCVKKGHEEDVKKIFD
                     FYDLEAVTIGRITAGHDYVLFHDGEEVCHIPVSSLTDDVLEEESLEKKPARIELAEQQP
                     AWIPDVDNVAEVLTALLAQSTIADKSSLYQQYDSQVRTNTVAGPGSDAGVLRVRGTHKG
                     LAMTTDGNGRFVYLSPEVGGQIALVEAAANIIASGAEPLAITDCLNYGDPTDPEIFWEL
                     HQSVQGMADACREFNTPVISGNVSLYNENNGQAIHPTPMVGMVGLIKNIDRVIPSFVQY
                     PGDKVYLVGQTRDDYAGSELQKMMTGDISGIVKSFDLHHVHQYMQRLLTTMENGLVSSA
                     HDLSEGGLGVALAETVFKTDLGLKVDFADQPAARLFSETPGRFIVTVAPDKATEFEQAL
                     GEDAHLIGEVTNSHWLMVKLANGELNENVAKLQKTWEEAIPCQLKSKD"
     CDS             20179..21633
                     /locus_tag="ctg22_18"
                     /transl_table=11
                     /translation="VPTEIKGLNEECGVFGVFDAANASQLTYYGLHTLQHRGQEGAGIV
                     STDGTELYQHRDRGLLAKVFADPAELKRLKGNAAIGHVRYGTSGHNSIANVQPFLFHFH
                     DGAVALAHNGNLTNAVTLRRELENEGAVFQSDSDTEILIHLIRKYINEGFIPALKKSLN
                     LVHGGFAYLLLQKDRLIAALDPNGIRPLCIGRLENGAYVVASETCALDIISAQFVRDVL
                     PGELIVIDKNGLHIDHYTTQTQLAICSMEYIYFARPDSIIHGVTVHNARKRMGKLLAKE
                     HPVDADMVIGVPNSSLSAASGYAEESGLPYEMGLIKSQYVARTFIQPTQELRELGVHMK
                     LSAVRGVVKGKRVVVVDDSIVRGTTSKQIVQMLKRAGAKEVHMLISSPPFKFPCFYGID
                     VSTRSELMAAHYSIEEMRQLIGADSLNFLSIDSLIKAINVPDAGDAPNGGLTVAYFDGK
                     YPTPLYDYEEGYLKSLSEQERLARKG"
ORIGIN
        1 ctggcgaact ccaattgaga tctttttgct taatctgcgt cattaaattt gttcaagtta
       61 tttattgcaa tctaccatta acaaagatat tattaaacga aaaaatcgca ccatccatga
      121 ttaaacatcc cttcatagat aattatgtct atattttaac gtaatcgaaa atgaaaggga
      181 atacattaat taagcattta ctttagcgag gtcagcggca taatcgattc cctttacatc
      241 taaatactca acaatttgat tgattgtaat aaatggtaca tgaactcggt tagcaaggac
      301 tgacagacta tcacgacgag ccatcgtgcc gtcacgcttt aacacttcga taataacagc
      361 aactggtgcc tttcctgcta aataggcaag atcaatagct gcttcggtgt gaccgattcg
      421 atctcttaat ccatgaggtt gggcgtaaag aggttgaatg tggccgggat gattaaagtc
      481 agatgcttgg gcagttggct tggcaatttg ccgaatcgtt gctgcgcggt caaaagcgga
      541 aacaccagta gtaacaccgg ttgcttctaa ggtaccatca gtagtaacca taaatggtgt
      601 ttggtgtggg tcagtgctat gctctaccat gggcttaaac gctaaatgct tagcaatatc
      661 ttcgcttact ggcacacaca tcaaaccatt tgcctcgttc aacatttcat agatagtatc
      721 agcgttgaca ttttcaccta aagctactaa atcaccttcg ttttcacgat cttcattatc
      781 ggctaagata atataaccac catttactaa ttggtttaat gcttcttcaa cagttgaaaa
      841 ttgactttgc ataatttata tactcctttg aaattctgaa agtgatagaa cagttacatt
      901 cgaatgtgtt attataataa cgaacgtttt aatttaaatc aacctatttt taaactaaaa
      961 cacgaataat attaaaagat ttcaaagggt aagtttgcta aagagctgga gaaaataaag
     1021 atttctcacc agctctacgc tctatcttta gagtaacaaa aaagtccaga acgagatatt
     1081 tttcgtcctg aactaatctt aggttgttct attttgtcat gtaatcacga gtcattggta
     1141 agtttttacc tgaaggaccc ttagttatca agtattgaat aacatcaata tttccagatt
     1201 caaatgatgc agcacatgct tgaagatata aatcccacat ccgtgtaaaa cgttcaccca
     1261 tcatatcaag gatttgagca cgatgttcat taaagttcat gtcccaaatt tcgagggtgc
     1321 gttgatagtg acggcgaagc atttcgatat cagcgatttg catatgattt tcttcaatgt
     1381 gaccgatcat ttcttcgaga ccaggtacat aaccgccagg gaagatatac ttgttaatcc
     1441 acccattata tgcaccgcct tgttgacgag tgataccatg aatcaaggca acaccatcat
     1501 cagcaaggca accttggata tctttaaagt aaaaacctag attttctttt ccaacgtgtt
     1561 caaacatacc aacggatgta atataatccc acttttggtc accaagttca cggtaatcaa
     1621 caagtttaac ttcggcaacg tcttgcaaac cttctttttc aatccgttcc ttaacaaagc
     1681 gatattgttc ttcgcttaaa gtaaccccag taacttttaa gccatattct tttgcagcag
     1741 ttaacattaa tgttccccaa ccacatccaa tatcaagcaa tgttttgcca ggctttggat
     1801 caagcttctt taagatgtga tgaaccttat caacttgtgc ttttgtaaga tcatcatggt
     1861 tgccatcagt aaaataagca catgagtaag ttagcgtatc atcaagccat aacttgtaga
     1921 agtcgttccc aacatcataa tgactttgga catcattttc gctctctttt tctgagtggc
     1981 cttgtttagg caaaaatttg cggaacttag aactccgcat aaaactatcg gcactttcat
     2041 atgctgattc gatcaattct tgaatgctac cctggatctc gattttctta tccatgtagg
     2101 cttccccaag tgcaattgag gcgttcttgg taatatcacg cattggaatt ttctcattaa
     2161 aggtgatagt tacctcagga gttccgtcac catagataac acttgatcca tcccaaaata
     2221 cgatctttac gggaatgtta aatgagtgct ttagtagtga cttgtagaac gtcttttcta
     2281 acatgaaacg catccttctt tctgcaataa taatattcat tataacaccc ttaaaataaa
     2341 agtgtttcaa gacaattaat gaaaacattt cataagaaag cgataaacta attgctgaaa
     2401 aaatgaaagc ttgctactat gctaattagt aggaaaaata gggagatgat tgaatgacga
     2461 atgcctggaa gcattttatt gagaatgtaa aactacggcg tttcactgtc ttattattaa
     2521 tcattgtcgt actctggcta atgaaatcaa tgatgaattt aattttattt acatttattc
     2581 ttacttatct tgttgttagt tgggtaagac tcgtccagcg atggttacca cgaatgtcga
     2641 caagtttaat tgtaatcgtt acctatgtat tgttaattgt tctcttatac ttaggggtga
     2701 cccgctattt accggtttta tctcggcaag ttgttaaaat ggtcaattca gtagttcatt
     2761 tctatagtac tcatcaagcg acgatgatat atcgttatgt cagccattac ataagtaccg
     2821 ccactattat gagtcaggtt cggcatggga taacaatcgc ggttagtact ttgacaagta
     2881 ttggtgcaat taccgtttca tttgtaatgt ctttaatctt gagctttttc tatacgcttg
     2941 aattaaaaca aatgaatgaa ttttctcata gctttttaga tagtgatttt ggctggtttt
     3001 tccaggatat tgattatttt ggtaaaaaat ttgtcaatac ttttggggta gtattagagg
     3061 cccaattttt tattgctatt tgcaatacag tgattaccac gattggccta ttatttatgc
     3121 ggatgccgca gatttttgcc ctatcgttaa ttgtgtttat ctttagtttg gttccggttg
     3181 ctggagtaat tatttcaaca atcccattgg cgatggttgg ttactcagtc ggtggaattc
     3241 gcgatgtggt ttacattatc atcatgatta tcatcatcca tactttggag gcctacgtct
     3301 taaatcctaa gtttatgtct agccggacag atctaccaat cttttatact tttatcgtat
     3361 tactgattgg tgaacatctt tttggtacat ggggattgat tgtgggggta ccaatcttta
     3421 ccttcttact tgatgtatta ggcgtaaagc ccattcgcgg tgcaaaaaga ataaaaaaag
     3481 aagtgtgagt gagagttagc cttgtggcga cgcaaagcta tttccataat gtcttgctac
     3541 tattcatgga aacagttaag gctgggagaa aaagttttct cccagttttt gttatccgaa
     3601 caatttatgt taattcattg gataaagtta ataaaaatcg aacttatttt gcaaaattgc
     3661 tgaaaaagtc ttgagttagt gtataatgaa attaagatag gtctaaagaa aggaagctga
     3721 tattcatgac agacatcgag attgcagaca aagcgacact ggaaccaatt acagaaattg
     3781 ccgagaaact cggactttca gaagacgcaa tcgaacaata tggtaagtat aaagccaaaa
     3841 ttgatttaaa tgtaaagcct ttacctgata aaaaacataa actaatttta gttacgtcca
     3901 tcaaccctac tcctgctggt gaagggaagt cgactgtcct cattggctta ggggatgcat
     3961 taaatcagtt aaattatcag acaacgattg caatgcgtga accatcgatg gggcctgttt
     4021 ttggaatcaa aggtggtgca actggtggtg gatatagtca ggttgttcca atggaagata
     4081 ttaacctgaa ctttaccggt gacttgcatg ctcttacaag tgctaataat actttggccg
     4141 ctttaattga taactatatt atgcgtgata atgcaatgaa ccttgatccg cggcgaatta
     4201 tctggaaacg ggtagaagac gttaacgatc gtgctctccg aaatgtagtt accggtcttg
     4261 gcggtccaat ggctggtgtt ccacgtgaaa caggctttaa catcacagct gcttccgagt
     4321 tgatggcaat tttatgtcta tcaactagtc ttcatgactt gaaagaacgg attagtcgaa
     4381 ttgtagtagg atatacatac gataaagaac cggtcacagt tggccagctt aattttcagg
     4441 atgcaattac aattatcttg aaagatgcat taaagcctaa ccttgtccaa actttagacc
     4501 atacgccaac aatcgtacat gggggaccat ttgccaacat tgcccatggg tgtaatagcg
     4561 ttttggcgac gcaaactgcc cttaaccttt ctgactatac tgtgacggaa gctggctttg
     4621 gggctgacct tggtggggaa aaattccttg atattaaaca acgtgttctt ggtaagcatc
     4681 cagatgcaat tgtcatcgta gcgactgtcc gagcgctaga atacaatggc ggtgccaaac
     4741 ttgcagactt aaatgatgaa aatcttgatg cgctgaaaaa aggaatggca aaccttaatc
     4801 gtcacattaa gaatatgcaa ttatatgggt taccaatcgt agttgcaatc aaccattttg
     4861 tcagtgatac cgataaagaa attcaaatga ttaaggatga ctgtgctaag caaaatgttg
     4921 aagcaatttt gactgatgct tgggctaagg gcggtaaagg tacccatgat ttggctaata
     4981 aagtagtcga acttgctgat agtccaagtg aatttactca tatctatgac gttcaagttg
     5041 atgaccttca aactaagtta gagaagattg ctaagcagat ttatggtgct aaagaagtat
     5101 catttagccg taaagcacaa aatcaattga agcgatttgc taagtatgga tggaatgact
     5161 tgccagtatg tattgctaag acccagtact catttacaga tgaccaaaaa caactcggtg
     5221 ccccaactga ctttactttc catattcggg aattggtacc aaagatcggt gccggctttg
     5281 tcgtggcatt agctggtaat atgatgacaa tgccaggcct ccctaaagaa ccagcggctg
     5341 taaacatgac gattgacgat aatggtaaaa ttaccggatt attctaaata accaacacaa
     5401 aacatcgatt gtgcaataac gtacatcgat gtttttttta caaaattttc aaggttagcg
     5461 ggttgaagtt attgatatac tgctatgtga acttaatcgt tttcttgtga aattataaaa
     5521 taaggactac agtaaaggta tatcgtttta taagtttaat taggtagagg tgaatggcta
     5581 atggaggaga aactacatgg cgcagatgtt gttattgata gtttgagaaa acacggggtt
     5641 aatctcgtct ttggtattcc cggagcgaag attgatcgtt tgtttgaagg actagatggt
     5701 caagacagtg aagatgcacc taaattaatt gttacccggc atgagcaaaa tgcggcgttt
     5761 atggcccaag cttatggtcg cttaaccgga aaaacagggg tcgcgatcac tacatctggc
     5821 ccaggagttg gtaatttagc aactgggatc atgacagcca acgcagaagg agatccaatg
     5881 ttagcgattg ggggacaagt acaacggaaa gaccttcacc gcgcaaccca ccaaagcacg
     5941 ccttcaactg aaattatggc accgattacg caatatagcg ctgaaattca agaccctaat
     6001 aatatttcag aaattatggc caatgcattt gaagcgagtc aggatgcacg taagggagca
     6061 gctttcgtta gtcttccaca agatgttgat gatgctgagg taactgaaaa gccattgcca
     6121 atttatgaaa cacctaagat gggtcctgct gatccaaatg acttacaaaa actagtcgaa
     6181 ctaattaaaa atagtaaaat gccggttatc ttagtcggtc aacggggcgc ggatgaagaa
     6241 attacgactg ctctccgcaa attattaagt gattatttat tgcctgttgt tgaaacatat
     6301 caagcggctg gagtagtatc acgtgactta gaacaacagt catactttgg acggattggc
     6361 cttttccgta atcaagtagg agatcagctt cttcaacaaa gcgaccttgt tattgctgtt
     6421 ggttatgatc cgattgaata tgaaccacgg aactggaaca aggaggggaa tctgcgaatt
     6481 gtaaaccttg ataccttgcc agcgcaaatt gataaccact atacaccaat catgcaacta
     6541 gttggtaata ttactacaag cttaactgag cttgataagt tactaaaggg gtatgaatat
     6601 cctcttgcag ccactgagca actcgctaag tataagcaag aacttgacca agataaaaag
     6661 attcaagtac cagcaagcaa tgatgccagt catccgttag cggttgtgca tgcaattcaa
     6721 gaaaatgtta ctgatgatat gcacgttgcg ctagatgtgg gttcccacta tatctggatg
     6781 gcacgacatt tccgttgcta ccaaccacga cacctgttaa ttagtaacgg gatgcaaaca
     6841 ctgggagttg gcttgccatg ggcgatggtt gcagcgatgc tttatcccga acataaatca
     6901 gtggcagttt gcggggatgg aggcttcctc ttctctgggg cggaattagc gacagccgtc
     6961 caacaccatc ttaatgttgt aacgattgta tggaatgatg gcggtcatta cgacatggtt
     7021 aaattccagg aagagatgaa gtattcgcaa gcagctggtg ttaaatttgg aaatgttgat
     7081 atcgttaagt atgctgagag ttttggtgca actggactgc gagtaaataa gccggctgac
     7141 cttactaagg taatcagcca agcctttaat attgatggcc cggttgtggt agatgttcca
     7201 gttgattaca gtaacaataa agaattagct gccaacttga ttgattcaca acttggctaa
     7261 gaggggaaca aagattatga caacattata tgaacacgga acgttagctg cgttgatggc
     7321 aggaaatttt gatggcacaa ttactgtcgg tgatttatta aaacatggtt cgatgggaat
     7381 tgggactttt actggcttag acggtgaggt tgttatcctg aataatgaag tgtaccaggc
     7441 cgtttcaagt ggtcaagtta accacattac agatatggat gctacaatgc catttgcttc
     7501 agtccatttt cctgctgaac aacaggatat aacattaagg aatgtaaact ttgctaaact
     7561 gaataatgat tttgttaaag aacatcagct tactaatgtt tttgcattct tacaattgag
     7621 tggtgagttt aagcacgtca aaattcggat tgctccgaag caagaaaagc catacccgac
     7681 tttactcgat gttgcgcaac accagcctga atttgcggct gataatatcg cagggacaat
     7741 catcggctac tatgcgccag aaatctttgg aacaataacg gcagcgggat ggcaccttca
     7801 ctttatcagt gatgatcgac aatttgctgg tcaccttctg gcgtttgatg ccccagaatt
     7861 aacaggtagc tttgaaattt ttgataacct ggaacaacat ctgccgattc ataatcaaga
     7921 atttcgggcg agtgaagttg atatggcaac tttacgtgat ggaattgcta aatcagaagg
     7981 aaatgcagac taaagaacaa atgaagcagc ggtataaata acgccgaaaa agggctccag
     8041 tgctcggtaa cgaactctgg aacccttttt gtgattttta aaatatcatc ttaagttgtc
     8101 gtttttaatg agttgattaa ttagtagtcg cttggaaaaa taatatttgc agatttacgg
     8161 agacggtata gagtcatatt aacaatttta gctagttcaa tccatcgttg ataattatcc
     8221 tgctgctgtg gcgattcggg gttagtaaag agttgtgcaa aatcgtttaa ctcgtcaaac
     8281 atggtgttat ctaagtagtg gttattgata acttgaatac tcccctgatt attaagataa
     8341 gtcactttct tagtatcgaa aatactgtca attattagcg tgtcgcgaag cctatattta
     8401 ttgccaaatg cttttgcggt gctaagctta cgggaatata caacagtaag ttaatatttc
     8461 ccagtatctt gtgctgcatg aatcatctgg tcaaaaatag tatgggttcc aataattcct
     8521 aatcgtaaca taagctagat ttcctggtta gccattttgt agatttgtac catgtcatca
     8581 taataaagaa ctttctgatc ccttgtgccc accggtagca ttaggacatg attgtgacat
     8641 ttccatttct gcttggcagg tatttcaata gtgcttttta tactaaatac ctaaaccttg
     8701 ttttaaaaaa tcgttcagtt gaagttttgg tgattcaaga atctaacccg accggcaaaa
     8761 aattcattac cttactccac cagctaacag atgtggcgga ccagcctgat aagtaatttt
     8821 aaatccgcaa tctcctttta caagcttggt tgacactaat tgctgaaatt aagtttcaag
     8881 aataacacca gcaattgacg gttatcccac gtgaacgcag caaaaatatt ttagcgtatt
     8941 tgcacaaaca ctatgcggaa aaggtaacaa ttaatgatag tgcaactgcg gtcaatatta
     9001 gtcccaaaga atgtattcgg tcatttaaga aaaacattca ccaaacgcca attgaatact
     9061 tattaaatta ccgggttgag caggcaaaga aattattgcg gcattcggag ctttcgatca
     9121 cggatattgt tttgcgggcg ggatttagta cgagtgccta ttttagtaaa atatttaagg
     9181 aacgggtagg gatgacacta cgggaatacc ggcagcgtca agggtagctt actttaagtt
     9241 taaaatttta cttatcaatg tttccatgtc tgctgggtta atgacttttt cttggcgcgg
     9301 cgtttggtct actaacgctt ggacaccagc gctaagctga tctcccagaa gatcatgtaa
     9361 ctgttgaaga gcaggaatcc cgctttgact aactttttgg ttggttagtg cgtggtagac
     9421 ggtttcaggg aatttatatg gactggcagt tgacacgata actgtgggag ttgtgtcatg
     9481 gctttgttgc tgatattgat gtgttacatg tgatgccact gcagtatgcg ggtcaataac
     9541 atatccatca tttaaatata ctcgtttaat ttcggcttca acttcatctg gggtcgcaaa
     9601 accagccaca aattgctcct gaagcttatt taatacggtg gaatctacct ggtagtgacc
     9661 gtcagtagct aattgcttca ttaatttagc aactgttacg cagctttcat cataaagatc
     9721 aaagaggagc cgctcaagat tacttgatac taaaatatcc attgctggtg agttagttag
     9781 gtaaaagttg cgtcgccgct catattttcc gctcttgaaa aagtcggtca atacattgtt
     9841 ttcattagaa gcacacagga gcttattaat tggtaagcct aattttttag cgtagtaacc
     9901 agcgaggata tcgccaaaat taccagtcgg cacggtgaaa ttaactttct cccctagttg
     9961 gatcccgcct gtatgaacaa gctgtccgta tgcagcaaaa tagtacacaa tttgggggat
    10021 aagccgcccg atattcattg aattagctga ggaaaagcag ttattatttt gcgcaaggcg
    10081 gtcattaaat gcttgatcgt tgaaaatatg tttaacgctt gtttgggcat catcaaaatt
    10141 acccttaatt gcgattgcgt ggaggttgga tccaggctgc cccagcattt ggcgtaattg
    10201 aaccggacta accccgccag cagggtagaa gacgattacc tgtgtgtctt tttgattgct
    10261 aaaccctcgc attgaggctg ttccagtatc accagaagtt gcggtaagga taacgatttg
    10321 tttttctagt tgggtgtttt gtgcagcacg tgacactaat tggggtaaca tttgtaaggc
    10381 gatatcctta aatgccagtg tcggcccgtg aaaaagctca agataataat tgctggcgtg
    10441 tttgggcgtt aatggggcaa ttaaacggtt atcccactga ctaccataag cggtatttgc
    10501 atttttcagt agttggtcgc tcgtaaattc atcaaaaaac cagttaagaa tagttgcagc
    10561 aagttgttgg tacggcaacg aaattaaggt tgcaaggtta taagttggtt gaggaaaatg
    10621 aagcggtaca taaagaccgc cgtctggaga aagtccttgt aagatagcag ttggtgattt
    10681 taaaatcgtt gataagtctc cctgagtgct acggtagtcc atgataattc ctccaatttc
    10741 aaaggtgatt ttattttaat tgtatgtttc ttatatgcta tggtacaatg ctgaaaatga
    10801 aaaaacaatg agaaactgag gtgggaaaat gaaaaacatt aaactgggac tgctcggtct
    10861 gggtacggtc gggtcaggag tcttacagat ggttcaacaa aatgcggata aaattctcga
    10921 tgttactggg tgcaagttaa cagttaaaac agctttagtt cgaaaccttg gtaactataa
    10981 taagtatgct gatgaaactt ctttaacaac tgattttgat gaaatcttga atgatgatga
    11041 aataaaaatt gtcgttgaac ttatgggtgg tattcatccg gctaaagaat atattacaac
    11101 cttattaaaa aatcataaga acgtggtcac agcgaacaag gatttgattg cgtcttatgg
    11161 cccagaattg atgactgtcg cgcatgaaaa tcactgtgac ttaatgtttg aagcgagtgt
    11221 ggctggtggg attcctattt tgcggacgat tgctaatagc tttacggcag ataaggttac
    11281 tgaagtaaag ggaattgtaa atggaacaac gaattacatc ttaacgcaaa tgagccagcg
    11341 gggatggtca taccaccaag cacttgccca agcacaacag ctgggatttg cagagagtga
    11401 tccaaccaat gacgtgacgg gtaaggatgc ggcttacaag atgattatat taagtcaatt
    11461 tgcatttgga actcaactag atattaagga cattgcggta gaagggattg accgattgaa
    11521 tgacgctgat gttcaacaag cagcgtcatt tggatacgta attaaattac tagggattac
    11581 caagctggtt aacaatggag tatttgtcga agttggccca gtgttaatcc cccgtgatca
    11641 tcctttagca acaatcaata atgaatttaa tgcagtaatg gttacagccc aagcggtcgg
    11701 tgatacgctc ttctatggcc gcggtgcagg gggcttgcca actgctaaca gtgtgttaag
    11761 tgatattaca acggtaacga aaaacattat cctgggaact aatgggaatc tctttaataa
    11821 ttaccaacaa ccttatattc cggcaaaact tgctgatata aaatatccat attatttatc
    11881 gttaaccttg ccggatgttc ctgggcaaat gttgaagcta acccagatga tgacggatat
    11941 taatgctagt tttcgtgaaa taacccaaac aaaagatggc aaaattgcgc acattgcaat
    12001 cattactcac cggatgagca aagaacaatt acagacatta ctaactaaag tggctaatga
    12061 tcagtcaatt aacttgtcgg cggcttataa agtgatggga taggaggaag tataatgatt
    12121 attcaagcac ctgcttccag tgctaatctt ggtccgggat ttgactcaat tgggattgca
    12181 gtctctttgt atttaaaatt agaagtcctt ggtccaagcg ataactggca agttgatcac
    12241 cagcttggga agctccctta tgatgagacg aatatgattg taacaacggc attaagtgtc
    12301 gcaccggatt tgccgccaca gcacctgcgg gtagtcagtg aaattccgat agcacatgga
    12361 ttaggaagta gttcaagcgc aattgttgct ggaatcgaat tagcaaatca gcttaagaac
    12421 ctgaacctta gcaaggaaga aaaagttgag attgccagcc agattgaagg ccatcctgat
    12481 aatgtcgcac cgactattct agggggatta gtagtgggga cacatattaa tgggcatttt
    12541 tctgcgattg aagcgccctt attcccctat gcttttgctg catatatccc gccttataat
    12601 ctaaaaacag ctgatgcgcg agctgccttg ccatatcaac tagaatattc ccaagctgtt
    12661 catgcgagcg cggttgctaa tacctttgtt gctagtttgt ttgctaaaaa ctatgatgta
    12721 gcgtttaaat taatggaggc agatcgcttt catgaaccat atcgcaaaga gctagttcca
    12781 gaattagatc aaattcgtga attaggaaaa aaacatggag cactagcaac atatttaagc
    12841 ggcgccggac caacagtaat gacagttatc gataatgaca attacggatt atttgaacag
    12901 gcagtacatg ctgcggggct aaagggaaaa gtagtccgtt tacacccaga tgttgaagga
    12961 gttaaactaa tataatttag gaaagaggct ggaaatggat tcggcctttt ttctttttta
    13021 tgaattttaa cgaactattt tatgttttaa ctttattaag ttcgattttt acattgaatt
    13081 ataaaaaaat ctttgctatc cttaaagcag atttgaggag gcattgttat gagtgacatt
    13141 agtgtagtaa tgggcagtaa atcagactgg ccaactgtta aagaaacttg tgatatttta
    13201 gatgaatttg gtgtttcata tgaaaagaac gtgatttctg ctcatcggat gccaaatgaa
    13261 atgttcgcgt ttgcgcaaaa tgcggttgat aatggggtca aagtaataat tgcatgtgcc
    13321 gggggagcag cccatcttcc cggaatgatt gcggcaaata cccccctgcc agtaattggg
    13381 atcccaggac agacaaaagc tcttggtggc atggactcgc ttttatcaat tgttcaaatg
    13441 ccagcgggaa ttccggtggc aaccactgcg attggaaaag caggcgctaa aaatgcagcg
    13501 ttattagcat tgcaaattct tgggatcaca gataagcata ttcaacaaca aatcatcgaa
    13561 tatcgacagg cgatgcatga tcaagcaaaa gaaagtgggc agtatcttga ataaatttat
    13621 tccacaaggc tcaactattg gcattattgg tggtggccaa ttgggacaga tgatggcatt
    13681 ggatgccaaa cagacgggga tgaaggttat tattttagat ccgacaccaa attgtccagc
    13741 ggggcaggtt gctgatgaac aaattgttgc tccttatgcc gatactaaag cgattgaaaa
    13801 gttagctgat aaagcggatg tattaaccta cgaatttgaa aatgttgatt taaatgcttt
    13861 ggaagatgta caggatcgcg tttatcttcc ccagggaact aatttgcttt acacgaccaa
    13921 aaatcgttta cgggaaaaga atttcttacg tcaggcaggg gtaaaaacag cacctttcat
    13981 ggcagtacat acttctgctg aattaaaaga tgcagtaaag aaaatcggtt acccagcagt
    14041 tttgaaaact agtgaagggg gatatgacgg acacggtcaa gaagtattac gtaataagga
    14101 tgacctcgat aagtgtgcgt ctattttagc cactggcgac tgtatcttag aaggctgggt
    14161 tccttttaac cgcgaatgtt cagtaatggt cggacgtaat gaagatggag aaataacggc
    14221 ttttcctgtt tcagaaaata ttcaccatga tgaaattcta catttaagca ttgtcccagc
    14281 aagaatctct tctgaattac aacaaaaggc gcaaaaaata gcggtgcaga ttgcccaagc
    14341 gattaatttg cgagggattt taggggttga aatgtttgta acagatgatg gagagatcta
    14401 tattaatgag cttgctcctc gtcctcacaa ttctggtcat tattcaattg aagcttgtaa
    14461 cttctcacag ttcgccatcc ataatcgagc aatttgtaac tggccactcc cgcaagtaga
    14521 gttattaaag ccggtggtaa tggtaaatgt tttaggtcag catgttaatg gagtccgaca
    14581 acagattcag aaaaaggcaa attggcattt tcatgattat gggaaagcag aagttcgtca
    14641 taaccggaaa atgggccacg ttacaatctt gactgatgat attgaagcta ctttagcaga
    14701 aattgacaat gcaggtatct ggggtgcata aagttcggct ttacgtaacc gcttttcctg
    14761 tgcgataata catttagaaa aaatagagag gatttttgac tgatgattga tcgttatacc
    14821 agtccaaaga tgaaaaagat ttggagctta gaaacacaat accaatgttg gttagatgtt
    14881 gagattgctg ctgatgaagc gtggagtaag cttgggcata ttccagcaga agatgtggaa
    14941 aagattaaaa agaatgccaa gttttctgtg gagggaattg cagagattga agcagtgact
    15001 catcatgatg tgattgcttt tacccgtgat gtttctaaat cattggggcc tgaacgaaag
    15061 tgggttcact acggaatgac gagtacagat gtagttgata ctgcacaagg cttgcgatta
    15121 aaaaaggcga acgatatcct tcgtcaagat attgataact ttatggatgt ccttaaagaa
    15181 ttagctgaaa aatataagta cacagtttgt atgggacgaa cacatggtat ccatgctgaa
    15241 ccaacaactt ttggcttgaa agctgctcgg tggtattcag aaatgaagcg taataaagaa
    15301 cgttttgaac atgctactaa gggtgtcgaa gcgggtaaaa tttctggtgc agtaggaact
    15361 tttgctgaaa ttgacccatt tgttgaggaa tatgtctgca aaaaacttgg cttacgtcct
    15421 caagaaatct ccacacaagt tcttccgcga gatttacatg ctgaatatat tgctaccatt
    15481 gcgcttattg gaacaagtat ggaagaaatg gcaaccgaga ttcgctctct tcaacgaacg
    15541 gaaatccatg aagtcgaaga acactttgcc aagggacaaa aaggatcttc tgctatgcca
    15601 cataagcgta atccaattgg ctcagaaaac attactggtt gtgcgcggat gctccggggc
    15661 tttatggtgc ctgcttatga agatgtttcg ctttggcatg aacgggatat ttctcattcc
    15721 agtgcagagc gaatgatttt accagatgca acttcattac ttgattacat gttgcggcgt
    15781 tttggtcgaa tcttaaagaa tctcgatgta ttccctgaaa caatgaagaa gaatatggat
    15841 aagacattgg gcttaattta cagtggtcgg gttcttttga agttggttaa cagtggaatg
    15901 actcgggaag cagcttatga tttgattcaa ccatataccg ctaagtgctg ggcagaacag
    15961 attccgttcc gtccattatt ggaagatgac ccaacaattc aaaagcaatt aactaaagaa
    16021 gatcttgatg atgcctttga ttaccactgg cacctccgcc atgttgatga catttataaa
    16081 aggctgggat tagactaatt taagttagtt taagaggcta gacgaacaaa aaagtttgcc
    16141 tagccttttt attatgcttt atttagtaaa acacgaacaa tttgaacgaa aaatcatata
    16201 aatatcgtaa ttcgtattga caatcgggag ggggaaagag tatattgttg tcataaaata
    16261 tcgaattaat tttcggatat taaaataaat gttcgttttt ttctgaaagg aagttccgta
    16321 aatggagaag ttattgtata ccggcaaggc aaagcagatg tggcaaactg aggatccagc
    16381 ggttttacga gtagtttatc tggaccaagc taccgccctc aacggaaaaa agaaggatca
    16441 ctttactggt aagggtaagg ctgccaatgc tatttcttcc ctcgtttttg gttacttaat
    16501 gaagcaagga attgagaccc actttattaa gaaactatca actaacgaag accttgtaaa
    16561 aaaatgtgag atgttcccgc ttgaatttgt aacgcggaat gtaattgctg gccattttgc
    16621 aagtcggtat ggactttcag aaggggaaga gcttccttca ccagttgagg aaacgttcta
    16681 taaaagcgat gagcttaatg atccctttat caatgaatcc gcaacgattg ctcttgagat
    16741 tgccagcaaa gaggagcttg cgcaaatgtg ggggatctgt cggaaggtca acaacttact
    16801 taaaccatta tttgccaaag ctaatttacg gttggttgac ttcaaactcg aatttggccg
    16861 tttaagtgat ggcaagatta ttcttgcaga tgaattttcg ccagataact gtcggttatg
    16921 ggatctgaca actatgcagc atatggataa agacgtatat cgacgcaaac ttgctgattt
    16981 aacccaaaca tatgatgagg tattggaacg gttagaagca gtgatgaagg aggaagcata
    17041 aatggtcaat gttcggattt tcgtaacgta taagcaatca gtctttgatc cgcagggaga
    17101 aacaattaag gatgcgatcc attctctagg tcatgatgaa gtaactgccg ttaaagttgg
    17161 gaaattcttt gacgttacct tagacacaaa tgaggatgag gtagcatcag cggtaaaaga
    17221 aattgctgat cagctccttg ttaatttcaa tatggaaact tatacatacc aagttatgga
    17281 ggaagcctag atgaaaattg cggtggttgt ttttccagga tccaattgcg atgtggattt
    17341 atatgaagcc cttcattccg tttgccatgc agatgtggag tatgtttctc accggcaaaa
    17401 aagtttagct ggttttgatg ctgtgatgtt accaggagga ttttcctatg gtgattatct
    17461 acgagctggc gcaattgctc ggtttaccaa tatcatgcct gcaataatca agatggcaaa
    17521 tgaggggaaa ccagtctttg gaacgtgtaa cggatttcaa attttgacag aagcaggtct
    17581 tttgccaggc ggactcaaac gcaatgatag ccaacgcttt gtttgcaaaa ctgttccttt
    17641 agaagtagtg aactcgcaca ctctttttac tagtcattac caggatcacg aacgaatcgc
    17701 attaccaatt gcgcatgccg atggtagtta ctatgcagat gaaaaaacat tagatgaact
    17761 ggaagcaaat aatcaaattg tttttcgtta cgcgactgaa aatccaaatg gtagtttacg
    17821 caacattgct ggaattacta ataagcacgg aaatgtctta ggcatgatgc cccatcctga
    17881 acgggcagta gaaactattc ttggcagtac ggatggctta cggttatttg aatccttgtt
    17941 agaaaacggc agaattaaag tggaggcata gttaatgaag caagcaatga ccccagaaga
    18001 gattaaagaa aagaaaccat acttagattg gagcttgaca gaagcagaat atgattacat
    18061 tcgtacccag ctcttggggc gattacccaa ttatactgaa actggcttgt tttctgcgat
    18121 gtggagtgag cactgttcat ataaaaagtc aaagccggtt ctgcgtctct tccctaataa
    18181 aaatgagcga gtattgcaag gccccggaga aggagcaggg gttgttgata ttgatgatgg
    18241 acaagcggtg gtattcaaag ctgaaagtca caatcatccg acaactgttg aaccttatca
    18301 aggagcagca accggtgtcg gtggaattct acgagacatt ttcagcatgg gggcacgacc
    18361 aatcgcttcc cttgattccc tccatttcgg tgaattagat aattcgacaa cgcggatgaa
    18421 agtaactaat actgttcggg gaattggtga ttacggtaat tgtatgggaa ttcctacaat
    18481 tgcgggtgaa acaacatttg atccatgcta ccagggcaat attctgtgta atgcaatgag
    18541 tgttggctta atggaccaaa aagatatcca gcagggtcgc gctgccggaa ttggaaatgc
    18601 agtgatgtat gtcggcgcta aaaccggccg tgatggaatt catggcgcca cctttgcttc
    18661 cgcagacttt aatgatgaaa atacgacgca acgttcggcg gttcaagttg gtaatccttt
    18721 tatggaaaaa ctcttattag aagcctgtct tgaccttatt agaaatcatc cagactggtt
    18781 agtaggaatc caagatatgg gggcagcagg gattgtttct tcaagtgcgg aaatggcttc
    18841 cgaaggtaaa agtggaatgg agctaaattt ggatcttgtt ccgcaacgtg aacccgggat
    18901 gtcggcttat gaaattatgc ttagtgaatc ccaagaacgg atgctacttt gcgtaaaaaa
    18961 aggtcatgaa gaagatgtca aaaagatttt tgatttttac gatcttgaag cggtcacaat
    19021 tggccggatt actgcgggtc atgattatgt tctctttcat gatggtgaag aagtatgtca
    19081 tatcccagtg tcgagtttaa cggatgacgt actagaagaa gaaagcctcg aaaaaaagcc
    19141 tgcgcggatt gaattagccg aacagcagcc agcgtggatt ccagatgttg ataacgttgc
    19201 tgaagtttta actgccttgc ttgctcagtc aacgattgcg gataaaagta gtctttatca
    19261 gcaatatgat tctcaagtac ggacaaacac agtggctggg cccgggagtg atgctggggt
    19321 tctgcgggtt cgtggaacac ataaagggtt agcgatgaca actgatggga acggtcggtt
    19381 tgtttacctt agtccagaag ttggcggaca aattgcctta gttgaagcag ctgccaacat
    19441 aattgccagt ggagctgagc cgttagcaat tactgactgc ttaaattatg gtgacccaac
    19501 tgatccagaa attttctggg aacttcatca atctgttcaa gggatggctg atgcttgccg
    19561 tgaatttaat accccggtta tttctgggaa tgtttcttta tataacgaaa acaacgggca
    19621 agcaattcat ccgacgccga tggttggaat ggttggtcta attaaaaata ttgatcgcgt
    19681 aattccttcg tttgttcaat acccgggaga taaggtttat ctagtgggcc aaactcgtga
    19741 tgattatgcg gggtctgagt tgcaaaaaat gatgaccggc gatattagcg gaattgttaa
    19801 gtcatttgac cttcaccatg ttcatcaata tatgcaacgt ttactgacga cgatggagaa
    19861 cggccttgtt tccagtgccc atgatttgag tgaaggtggt ctcggagtag ccttagcaga
    19921 aacggtcttc aaaactgatt tagggttgaa agttgacttt gctgatcagc cagcagctcg
    19981 cctgtttagt gagactcctg gaagatttat cgtgacggtt gctcccgaca aggcaactga
    20041 atttgaacag gcattaggag aagatgcgca cctaatcgga gaagttacaa atagccactg
    20101 gttaatggtt aaactggcaa atggtgaact caatgaaaat gttgcgaaat tacaaaaaac
    20161 atgggaggag gcaattccgt gccaactgaa atcaaaggat taaatgaaga atgtggggtc
    20221 tttggggttt ttgatgcggc taacgctagt caattaacct attacggcct gcatactctt
    20281 cagcaccgcg gccaagaagg agcaggaatt gtctcaactg atgggacgga actttatcaa
    20341 caccgtgacc gaggattgtt ggcgaaagtg tttgctgatc cggctgagct taaacgatta
    20401 aaaggaaacg ctgcgattgg ccatgtgcgt tatgggacaa gtggacataa ttcgattgct
    20461 aatgttcaac ccttcctttt tcactttcat gatggtgctg ttgcactcgc ccacaatggt
    20521 aatttaacta atgctgttac ccttcgtcgt gaattggaaa atgaaggggc agttttccag
    20581 tcagattctg atacggaaat tttaattcac cttatccgga aatatattaa tgaaggtttt
    20641 attcctgctt tgaagaaaag cctcaacctt gtccatggtg gatttgccta cctattactg
    20701 caaaaagatc ggttgattgc ggctttggat cctaatggga ttcgtccttt atgtattgga
    20761 aggttagaaa atggtgctta tgttgttgct agtgagactt gtgctttaga tattattagt
    20821 gctcaatttg tgcgtgatgt tttgccagga gaattaatag ttattgataa aaatgggtta
    20881 catattgacc attacactac ccaaactcag ctggcaattt gctcaatgga gtatatctat
    20941 tttgcccgtc ctgattctat tattcatggg gtaacggtac ataatgcgcg gaaacgaatg
    21001 ggaaagttat tagcaaagga acatccggtt gatgctgata tggtgattgg agtacctaac
    21061 tcatcgttgt ctgctgctag tggatatgct gaagaaagtg gccttccata tgaaatgggg
    21121 ttaataaaga gccaatatgt tgcgcgaacg tttattcaac caactcaaga gttacgggag
    21181 ttaggcgttc atatgaaact gtcagctgtc cgcggagttg taaaaggaaa aagagtggta
    21241 gtagtcgacg attcgattgt gcgcggaaca acttctaagc agattgtcca gatgctaaaa
    21301 agagctgggg ctaaagaagt tcatatgctt atctcctcac caccatttaa gtttccgtgt
    21361 ttctatggga ttgacgtatc aacgcgttca gaactgatgg ctgctcatta ctccattgaa
    21421 gaaatgcggc agttaattgg tgcagattct cttaattttt tgagtattga tagtttaatc
    21481 aaagcaatta acgtaccaga tgcaggagat gctcctaatg gtggacttac cgtggcttat
    21541 tttgatggga agtacccaac gccactttat gattatgaag aagggtactt aaagtcgtta
    21601 agcgaacaag agcgattagc aagaaagggg taagaggatg agtcgttatc aagatgcagg
    21661 ggtggatgta aatgccgggt acgaacttgt tcaccgtatt aaagatgcag tcaaatcaac
    21721 tgatcgccca ggtgtgattg ggggaattgg cagctttggg gggatgtttg acttagaaaa
    21781 attacaggta cggcatccgg tccttgtctc tggcactgat ggtgtgggaa cgaaactctt
    21841 aattgcccaa caaatgaata agcacgatac aatcgggatc gatgttgtcg caatgtgcgt
    21901 taatgatgtc ttggcgcagg gagcggaacc aataacattt ctcgactaca ttgcgaccgg
    21961 ccataatgat ccggctaaga tggcagcgat tgttagcgga gtagcgactg gttgccgaga
    22021 agctggagcc gctttaattg gtggagaaac agcagaaatg ccagatatgt atgcagccaa
    22081 tgagtatgac ctggcaggaa cag
//
