Select genomic region:
Overview
47.1
68.1
112.1

### Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaNKMGLCHI_79 (original name was: gnl|Prokka|NKMGLCHI_79)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 47.1 | lanthipeptide-class-ii,RiPP-like | 1 | 18,603 |

gnlProkkaNKMGLCHI_100 (original name was: gnl|Prokka|NKMGLCHI_100)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 68.1 | NRPS | 1 | 13,974 |

gnlProkkaNKMGLCHI_144 (original name was: gnl|Prokka|NKMGLCHI_144)

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 112.1 | T3PKS | 1 | 4,476 |

Region | Type | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | ---
Region 47.1 | lanthipeptide-class-ii,RiPP-like | 1 | 18,603 |
Region 68.1 | NRPS | 1 | 13,974 |
Region 112.1 | T3PKS | 1 | 4,476 |

No secondary metabolite regions were found in these records:
  gnlProkkaNKMGLCHI_1 (original name was: gnl|Prokka|NKMGLCHI_1)
  gnlProkkaNKMGLCHI_2 (original name was: gnl|Prokka|NKMGLCHI_2)
  gnlProkkaNKMGLCHI_3 (original name was: gnl|Prokka|NKMGLCHI_3)
  gnlProkkaNKMGLCHI_4 (original name was: gnl|Prokka|NKMGLCHI_4)
  gnlProkkaNKMGLCHI_5 (original name was: gnl|Prokka|NKMGLCHI_5)
  gnlProkkaNKMGLCHI_6 (original name was: gnl|Prokka|NKMGLCHI_6)
  gnlProkkaNKMGLCHI_7 (original name was: gnl|Prokka|NKMGLCHI_7)
  gnlProkkaNKMGLCHI_8 (original name was: gnl|Prokka|NKMGLCHI_8)
  gnlProkkaNKMGLCHI_9 (original name was: gnl|Prokka|NKMGLCHI_9)
  gnlProkkaNKMGLCHI_10 (original name was: gnl|Prokka|NKMGLCHI_10)
  gnlProkkaNKMGLCHI_11 (original name was: gnl|Prokka|NKMGLCHI_11)
  gnlProkkaNKMGLCHI_12 (original name was: gnl|Prokka|NKMGLCHI_12)
  gnlProkkaNKMGLCHI_13 (original name was: gnl|Prokka|NKMGLCHI_13)
  gnlProkkaNKMGLCHI_14 (original name was: gnl|Prokka|NKMGLCHI_14)
  gnlProkkaNKMGLCHI_15 (original name was: gnl|Prokka|NKMGLCHI_15)
  gnlProkkaNKMGLCHI_16 (original name was: gnl|Prokka|NKMGLCHI_16)
  gnlProkkaNKMGLCHI_17 (original name was: gnl|Prokka|NKMGLCHI_17)
  gnlProkkaNKMGLCHI_18 (original name was: gnl|Prokka|NKMGLCHI_18)
  gnlProkkaNKMGLCHI_19 (original name was: gnl|Prokka|NKMGLCHI_19)
  gnlProkkaNKMGLCHI_20 (original name was: gnl|Prokka|NKMGLCHI_20)
  gnlProkkaNKMGLCHI_21 (original name was: gnl|Prokka|NKMGLCHI_21)
  gnlProkkaNKMGLCHI_22 (original name was: gnl|Prokka|NKMGLCHI_22)
  gnlProkkaNKMGLCHI_33 (original name was: gnl|Prokka|NKMGLCHI_33)
  gnlProkkaNKMGLCHI_44 (original name was: gnl|Prokka|NKMGLCHI_44)
  gnlProkkaNKMGLCHI_55 (original name was: gnl|Prokka|NKMGLCHI_55)
  gnlProkkaNKMGLCHI_58 (original name was: gnl|Prokka|NKMGLCHI_58)
  gnlProkkaNKMGLCHI_59 (original name was: gnl|Prokka|NKMGLCHI_59)
  gnlProkkaNKMGLCHI_60 (original name was: gnl|Prokka|NKMGLCHI_60)
  gnlProkkaNKMGLCHI_61 (original name was: gnl|Prokka|NKMGLCHI_61)
  gnlProkkaNKMGLCHI_62 (original name was: gnl|Prokka|NKMGLCHI_62)
  gnlProkkaNKMGLCHI_63 (original name was: gnl|Prokka|NKMGLCHI_63)
  gnlProkkaNKMGLCHI_64 (original name was: gnl|Prokka|NKMGLCHI_64)
  gnlProkkaNKMGLCHI_65 (original name was: gnl|Prokka|NKMGLCHI_65)
  gnlProkkaNKMGLCHI_66 (original name was: gnl|Prokka|NKMGLCHI_66)
  gnlProkkaNKMGLCHI_67 (original name was: gnl|Prokka|NKMGLCHI_67)
  gnlProkkaNKMGLCHI_68 (original name was: gnl|Prokka|NKMGLCHI_68)
  gnlProkkaNKMGLCHI_69 (original name was: gnl|Prokka|NKMGLCHI_69)
  gnlProkkaNKMGLCHI_70 (original name was: gnl|Prokka|NKMGLCHI_70)
  gnlProkkaNKMGLCHI_71 (original name was: gnl|Prokka|NKMGLCHI_71)
  gnlProkkaNKMGLCHI_72 (original name was: gnl|Prokka|NKMGLCHI_72)
  gnlProkkaNKMGLCHI_73 (original name was: gnl|Prokka|NKMGLCHI_73)
  gnlProkkaNKMGLCHI_74 (original name was: gnl|Prokka|NKMGLCHI_74)
  gnlProkkaNKMGLCHI_75 (original name was: gnl|Prokka|NKMGLCHI_75)
  gnlProkkaNKMGLCHI_76 (original name was: gnl|Prokka|NKMGLCHI_76)
  gnlProkkaNKMGLCHI_77 (original name was: gnl|Prokka|NKMGLCHI_77)
  gnlProkkaNKMGLCHI_78 (original name was: gnl|Prokka|NKMGLCHI_78)
  gnlProkkaNKMGLCHI_80 (original name was: gnl|Prokka|NKMGLCHI_80)
  gnlProkkaNKMGLCHI_81 (original name was: gnl|Prokka|NKMGLCHI_81)
  gnlProkkaNKMGLCHI_82 (original name was: gnl|Prokka|NKMGLCHI_82)
  gnlProkkaNKMGLCHI_83 (original name was: gnl|Prokka|NKMGLCHI_83)
  gnlProkkaNKMGLCHI_84 (original name was: gnl|Prokka|NKMGLCHI_84)
  gnlProkkaNKMGLCHI_85 (original name was: gnl|Prokka|NKMGLCHI_85)
  gnlProkkaNKMGLCHI_86 (original name was: gnl|Prokka|NKMGLCHI_86)
  gnlProkkaNKMGLCHI_87 (original name was: gnl|Prokka|NKMGLCHI_87)
  gnlProkkaNKMGLCHI_88 (original name was: gnl|Prokka|NKMGLCHI_88)
  gnlProkkaNKMGLCHI_89 (original name was: gnl|Prokka|NKMGLCHI_89)
  gnlProkkaNKMGLCHI_90 (original name was: gnl|Prokka|NKMGLCHI_90)
  gnlProkkaNKMGLCHI_91 (original name was: gnl|Prokka|NKMGLCHI_91)
  gnlProkkaNKMGLCHI_92 (original name was: gnl|Prokka|NKMGLCHI_92)
  gnlProkkaNKMGLCHI_93 (original name was: gnl|Prokka|NKMGLCHI_93)
  gnlProkkaNKMGLCHI_94 (original name was: gnl|Prokka|NKMGLCHI_94)
  gnlProkkaNKMGLCHI_95 (original name was: gnl|Prokka|NKMGLCHI_95)
  gnlProkkaNKMGLCHI_96 (original name was: gnl|Prokka|NKMGLCHI_96)
  gnlProkkaNKMGLCHI_97 (original name was: gnl|Prokka|NKMGLCHI_97)
  gnlProkkaNKMGLCHI_98 (original name was: gnl|Prokka|NKMGLCHI_98)
  gnlProkkaNKMGLCHI_99 (original name was: gnl|Prokka|NKMGLCHI_99)
  gnlProkkaNKMGLCHI_101 (original name was: gnl|Prokka|NKMGLCHI_101)
  gnlProkkaNKMGLCHI_102 (original name was: gnl|Prokka|NKMGLCHI_102)
  gnlProkkaNKMGLCHI_103 (original name was: gnl|Prokka|NKMGLCHI_103)
  gnlProkkaNKMGLCHI_104 (original name was: gnl|Prokka|NKMGLCHI_104)
  gnlProkkaNKMGLCHI_105 (original name was: gnl|Prokka|NKMGLCHI_105)
  gnlProkkaNKMGLCHI_106 (original name was: gnl|Prokka|NKMGLCHI_106)
  gnlProkkaNKMGLCHI_107 (original name was: gnl|Prokka|NKMGLCHI_107)
  gnlProkkaNKMGLCHI_108 (original name was: gnl|Prokka|NKMGLCHI_108)
  gnlProkkaNKMGLCHI_109 (original name was: gnl|Prokka|NKMGLCHI_109)
  gnlProkkaNKMGLCHI_110 (original name was: gnl|Prokka|NKMGLCHI_110)
  gnlProkkaNKMGLCHI_111 (original name was: gnl|Prokka|NKMGLCHI_111)
  gnlProkkaNKMGLCHI_112 (original name was: gnl|Prokka|NKMGLCHI_112)
  gnlProkkaNKMGLCHI_113 (original name was: gnl|Prokka|NKMGLCHI_113)
  gnlProkkaNKMGLCHI_114 (original name was: gnl|Prokka|NKMGLCHI_114)
  gnlProkkaNKMGLCHI_115 (original name was: gnl|Prokka|NKMGLCHI_115)
  gnlProkkaNKMGLCHI_116 (original name was: gnl|Prokka|NKMGLCHI_116)
  gnlProkkaNKMGLCHI_117 (original name was: gnl|Prokka|NKMGLCHI_117)
  gnlProkkaNKMGLCHI_118 (original name was: gnl|Prokka|NKMGLCHI_118)
  gnlProkkaNKMGLCHI_119 (original name was: gnl|Prokka|NKMGLCHI_119)
  gnlProkkaNKMGLCHI_120 (original name was: gnl|Prokka|NKMGLCHI_120)
  gnlProkkaNKMGLCHI_121 (original name was: gnl|Prokka|NKMGLCHI_121)
  gnlProkkaNKMGLCHI_122 (original name was: gnl|Prokka|NKMGLCHI_122)
  gnlProkkaNKMGLCHI_123 (original name was: gnl|Prokka|NKMGLCHI_123)
  gnlProkkaNKMGLCHI_124 (original name was: gnl|Prokka|NKMGLCHI_124)
  gnlProkkaNKMGLCHI_125 (original name was: gnl|Prokka|NKMGLCHI_125)
  gnlProkkaNKMGLCHI_126 (original name was: gnl|Prokka|NKMGLCHI_126)
  gnlProkkaNKMGLCHI_127 (original name was: gnl|Prokka|NKMGLCHI_127)
  gnlProkkaNKMGLCHI_128 (original name was: gnl|Prokka|NKMGLCHI_128)
  gnlProkkaNKMGLCHI_129 (original name was: gnl|Prokka|NKMGLCHI_129)
  gnlProkkaNKMGLCHI_130 (original name was: gnl|Prokka|NKMGLCHI_130)
  gnlProkkaNKMGLCHI_131 (original name was: gnl|Prokka|NKMGLCHI_131)
  gnlProkkaNKMGLCHI_132 (original name was: gnl|Prokka|NKMGLCHI_132)
  gnlProkkaNKMGLCHI_133 (original name was: gnl|Prokka|NKMGLCHI_133)
  gnlProkkaNKMGLCHI_134 (original name was: gnl|Prokka|NKMGLCHI_134)
  gnlProkkaNKMGLCHI_135 (original name was: gnl|Prokka|NKMGLCHI_135)
  gnlProkkaNKMGLCHI_136 (original name was: gnl|Prokka|NKMGLCHI_136)
  gnlProkkaNKMGLCHI_137 (original name was: gnl|Prokka|NKMGLCHI_137)
  gnlProkkaNKMGLCHI_138 (original name was: gnl|Prokka|NKMGLCHI_138)
  gnlProkkaNKMGLCHI_139 (original name was: gnl|Prokka|NKMGLCHI_139)
  gnlProkkaNKMGLCHI_140 (original name was: gnl|Prokka|NKMGLCHI_140)
  gnlProkkaNKMGLCHI_141 (original name was: gnl|Prokka|NKMGLCHI_141)
  gnlProkkaNKMGLCHI_142 (original name was: gnl|Prokka|NKMGLCHI_142)
  gnlProkkaNKMGLCHI_143 (original name was: gnl|Prokka|NKMGLCHI_143)
  gnlProkkaNKMGLCHI_145 (original name was: gnl|Prokka|NKMGLCHI_145)
  gnlProkkaNKMGLCHI_146 (original name was: gnl|Prokka|NKMGLCHI_146)
  gnlProkkaNKMGLCHI_147 (original name was: gnl|Prokka|NKMGLCHI_147)
  gnlProkkaNKMGLCHI_148 (original name was: gnl|Prokka|NKMGLCHI_148)
  gnlProkkaNKMGLCHI_149 (original name was: gnl|Prokka|NKMGLCHI_149)
  gnlProkkaNKMGLCHI_150 (original name was: gnl|Prokka|NKMGLCHI_150)
  gnlProkkaNKMGLCHI_151 (original name was: gnl|Prokka|NKMGLCHI_151)

Compact view
gnlProkkaNKMGLCHI_79 - Region 1 - RiPP-like,lanthipeptide-class-ii
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 18,603 nt. (total: 18,603 nt) Show pHMM detection rules used
Region on contig edge.
lanthipeptide-class-ii: cds(LANC_like and DUF4135)
RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Lanthipeptides
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Lanthipeptide predictions
Shows the possible core peptides for each biosynthetic enzyme.
Includes CompaRiPPson results for any available databases, with a detailed explanation here.

#### Lanthipeptide(s) for ctg47_11

ctg47_9
Leader:
MSNKDLNNIVGG
Core:
A F E E M S I Q Q M T E I Q G L G V T Q V Q S T P T V A I S R A G I A A S R A S S V R C A R W V S A A A G G A Y T W K K H H
Core with dehydrations:
A F E E M Dha I Q Q M Dhb E I Q G L G V Dhb Q V Q Dha Dhb P Dhb V A I Dha R A G I A A Dha R A Dha Dha V R Cys A R W V Dha A A A G G A Y Dhb W K K H H

#### MIBiG 3.1 matches for ctg47_9

8.1% BGC0000582 (ADR72962.1): Linaridin: cypemycin
23
S T P T V A
28
+T P T V A
4
A T P T V A
9

#### antiSMASH-DB 4.0 matches for ctg47_9

40.3% NZ_CP045729.1: Lanthipeptides: allorf_1568662_1568871_lanthipeptide
11
T E I Q G L G V T Q V Q S T P T V A I S R A G I A A S R A S S V R C A R W V S A A A G G A Y T W K K H H
62
T I Q G G Q++P + I S+A S S V R C A+W V S A +G +W K H H
1
T S I Q G N G A E S A Q T S P L I P I S K A-------S S V R C A K W V S A I S G--L S W A K H H
43
30.6% NZ_CP045729.1: Lanthipeptides: LG045_RS07910_lanthipeptide
17
G V T Q V Q S T P T V A I S R A G I A A S R A S S V R C A R W V S A A A G G A Y T W K
59
G Q S T P A I S R ++ +R S S +C W+S +A G G ++K
1
G T E T A Q S T P--A I S R V T L S I A R K S S A K C I S W I S F S A G G L N S Y K
41
22.6% NZ_FPCC01000026.1: Lanthipeptides: BM377_RS12925_lanthipeptide
1
A F E E M S I Q Q M T E I Q G L G V T Q V Q S T P T V A I S R A G I A A S R A S S V R C
44
A F E E+ + M ++Q G G + ++T +++ A A++ S S +C
1
A F E E L D V D D M Q Q V Q G A G D V E A E T T V P L S V V I A T A A S A I Y S S K K C
44
with 8 more sequence matches
22.6% NZ_KB976303.1 and 1 other:
NZ_KB976303.1 Lanthipeptides: IGY_RS26035_lanthipeptide
Lanthipeptides: IGY_RS26045_lanthipeptide
25
P T V A I S R A G I A A S R A S S V R C A R W V S A A A G
53
P T V I S R A S S C V S A +G
9
P T V------I V V S R A S S K A C M S G V S A I S G
31
21.0% NZ_KN125582.1: Lanthipeptides: DJ91_RS27550_lanthipeptide
25
P T V A I S R A G I A A S R A S S V R C A R W V S A A A G
53
P T V I S R S S +C A +S A +G
9
P T V------I V V S R I S S A K C A S T I S A I S G
31
17.7% NZ_FPCC01000026.1: Lanthipeptides: BM377_RS12915_lanthipeptide
1
A F E E M S I Q Q M T E I Q G L G V T Q V Q S T P T V A I S R A
32
A+E+++ + M Q G G T+ + T ++A I+ A
1
A Y E D L N T E D M Q N T Q G A G D T E A E-T V S L A I T G A
31
16.1% NZ_CP031746.1: Lanthipeptides: allorf_1813979_1814164_lanthipeptide
42
V R C A R W V S A A---A G G A Y T W K K
60
V C A R W V + A G T W+
5
V G C A R W V P C S L L G A G C P V T W R P
26
14.5% NZ_LT800494.1: Lanthipeptides: B7E07_RS02625_lanthipeptide
17
G V T Q V Q S T P T V A I S R A G I A A
36
G V + Q+T P T+A++ A + A
2
G V A E P Q A T P T I A L T S A L V G A
21
12.9% NZ_CP094681.1: Lanthipeptides: K5I26_RS05295_lanthipeptide
20
Q V Q S T P T V A I S R A G I A A S R A S S V R C A R W V S
49
+V Q V G I R ++ C A +++
6
E V Q E A Q K V C C P D K G I E R G R T T T S D C A L F L T
35
12.9% NZ_FPCC01000026.1: Lanthipeptides: BM377_RS12905_lanthipeptide
1
A F E E M S I Q Q M T E I Q G L G V T Q V Q S T P T V
27
+F E+++ + M Q G G ++T P +
1
S F E D L N T E D M Q N T Q G A G D V D A E T T P V I
27
12.9% NZ_PVMZ01000043.1 and 1 other:
NZ_PVMZ01000043.1 Lanthipeptides: CLV67_RS49775_lanthipeptide
Lanthipeptides: CLV67_RS49775_lanthipeptide
39
A S S V R C A R W V S A A A G G
54
+S S R C A ++ A G G
1
S S S T R C A E S I A R A T G G
16
ctg47_21
Leader:
MATSQQEVALKGS
Core:
R E R C N L S L Q A I R V S Q L T K L M C T R S K L L A N A N K C Y N L K
Core with dehydrations:
R E R Cys N L Dha L Q A I R V Dha Q L Dhb K L M Cys Dhb R Dha K L L A N A N K Cys Y N L K

#### antiSMASH-DB 4.0 matches for ctg47_21

20.5% NZ_CP020327.1: Lanthipeptides: B5S25_RS25065_lanthipeptide
15
Q L T K L M C T R S K L L A N A N K C Y N L
36
+L T K++ + +L+ N K Y L
3
K L T K V L R R Q H R L V I N K K K V Y R L
24
18.9% NZ_AP018268.1: Lanthipeptides: CDC39_RS06790_lanthipeptide
17
T K L M C T R S K L L A N A N K
32
T ++C R + N A N K
7
T P I I C L R Y T M F R N A N K
22
18.9% NZ_JALMDK010000007.1: Lanthipeptides: MZC64_RS28180_lanthipeptide
13
V S Q L T K L M C T R S K L L A
28
S +T+L C T R+ L +
3
T S V I T R L A C T R T P L C S
18
allorf_10987_11124
Leader:
MQLLHNLLHPFEKYSIYNA
Core:
Y S P S S L C S I V I R K M F F L A F Y I K R C S F
Core with dehydrations:
Y Dha P Dha Dha L Cys Dha I V I R K M F F L A F Y I K R Cys Dha F

#### Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine
Lanthipeptides
Core peptide predictions
Lists the possible core peptides in the region. Each core peptide lists the number of lanthionine bridges, possible molecular weights, and the scores for cleavage site prediction and RODEO.

ctg47_9 - Class II
  Cleavage pHMM score: -0.90
  RODEO score: 0
  Monoisotopic mass: 6370.3 Da
  Molecular weight: 6374.2 Da
  Number of bridges: 1
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    6392.2 Da N = 1
    6410.2 Da N = 2
    6428.2 Da N = 3
    6446.2 Da N = 4
    6464.3 Da N = 5
    6482.3 Da N = 6
    6500.3 Da N = 7
    6518.3 Da N = 8
    6536.3 Da N = 9
    6554.4 Da N = 10
    6572.4 Da N = 11
ctg47_21 - Class II
  Cleavage pHMM score: -7.10
  RODEO score: 0
  Monoisotopic mass: 4189.3 Da
  Molecular weight: 4192.0 Da
  Number of bridges: 3
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    4210.0 Da N = 1
    4228.0 Da N = 2
allorf_10987_11124 - Class II
  Cleavage pHMM score: -7.30
  RODEO score: 0
  Monoisotopic mass: 3015.6 Da
  Molecular weight: 3017.7 Da
  Number of bridges: 2
  Alternative weights
    (assuming N unmodified Ser/Thr residues)
    3035.7 Da N = 1
    3053.7 Da N = 2
    3071.7 Da N = 3

gnlProkkaNKMGLCHI_100 - Region 1 - NRPS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 13,974 nt. (total: 13,974 nt) Show pHMM detection rules used
Region on contig edge.
NRPS: cds(Condensation and (AMP-binding or A-OX))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
NRPS/PKS domains
KnownClusterBlast
NRPS/PKS modules
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Detailed domain annotation
Shows NRPS- and PKS-related domains for each feature that contains them. Click on each domain for more information about the domain's location, consensus monomer prediction, and other details.
A domain glossary is available here, and an explanation of the visualisation is available here.
Selected features only
Show module domains
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.

Module view
Shows module structures for each candidate cluster in NRPS and PKS regions.
Genes are shown in predicted order, and are only present when containing at least one complete module.
A domain glossary is available here, and an explanation of the visualisation is available here.
Legend
NRPS/PKS products
NRPS/PKS substrates
Predicted core structure(s)
Shows estimated product structure and polymer for each candidate cluster in the region. To show the product, click on the expander or the candidate cluster feature drawn in the overview.
For candidate cluster 1, location 0 - 13974:
Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:
  (Ala) + (X) + (Thr)

Direct lookup in NORINE database: strict or relaxed
Link to NORINE database query form
NRPS/PKS substrate predictions
Shows the predicted substrates for each adenylation domain and acyltransferase within genes. Each gene prediction can be expanded to view detailed predictions of each domain. Each prediction can be expanded to view the predictions by tool (and, for some tools, further expanded for extra details).

ctg68_2: Ala
  Search NORINE for peptide: strict or relaxed
  AMP-binding (7..393): Ala
  nrpys: Ala
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
    Small clusters prediction:
      Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
    Single AA prediction:
      ala (Ala)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DLFNNALTYK
    Nearest Stachelhaus code(s):
      Ala DLFNNALTYK (76% 8Å match)
    Stachelhaus code match:
      100% (strong)
ctg68_3: X
  AMP-binding (267..640): X
  nrpys: (unknown)
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      N/A
    Small clusters prediction:
      pro (Pro)
    Single AA prediction:
      pro (Pro)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DVRHFALLAK
    Nearest Stachelhaus code(s):
      Asp DVRHFALMAK (74% 8Å match)
    Stachelhaus code match:
      90% (moderate)
ctg68_4: Thr
  Search NORINE for peptide: strict or relaxed
  AMP-binding (484..878): Thr
  nrpys: Thr
  SVM prediction details:
    Predicted physicochemical class:
      hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
    Large clusters prediction:
      Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
    Small clusters prediction:
      thr (Thr)
    Single AA prediction:
      thr (Thr)
  Stachelhaus prediction details:
    Stachelhaus sequence:
      DFWNIGMVHK
    Nearest Stachelhaus code(s):
      Thr DFWNIGMVHK (91% 8Å match)
    Stachelhaus code match:
      100% (strong)

gnlProkkaNKMGLCHI_144 - Region 1 - T3PKS
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
More detailed help is available here.
Download region GenBank file
Download region SVG
Location: 1 - 4,476 nt. (total: 4,476 nt) Show pHMM detection rules used
Region on contig edge.
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
Gene overview
KnownClusterBlast
Gene/CDS overview
A brief tabular summary of genes/CDS features within the region.
Filtering the table will also search biosynthetic profiles and gene function data. If enabled, the overview will then zoom to show the area covered by the filtered selection.
Genes selected in the region drawing above will be marked in the table with an indicator to the left of the gene name.
Filter:
Automatically zoom to filtered/selected features

Identifier | Product | Length | Function | Sequence | NCBI Blast | Filter details
--- | --- | --- | --- | --- | --- | ---
|  | NT | AA |  | NT | AA |  |

No genes match the given filter
Similar known gene clusters from MIBiG 3.1
Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
Click on an accession to open that entry in the MiBIG database.

No matches found.