LOCUS       gnlProkkaGEPDGMEL_64   15650 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GEPDGMEL_64.
ACCESSION   gnlProkkaGEPDGMEL_64
VERSION     gnlProkkaGEPDGMEL_64
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 08:39:25
            Original ID  :: gnl|Prokka|GEPDGMEL_64
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 1922
            Orig. end    :: 17572
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15650
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:10650]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..10650
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..15650
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15650
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(665..1204)
                     /locus_tag="ctg27_6"
                     /transl_table=11
                     /translation="MNNDVEKVLYTQDQVNQRLDELANTLTEKYQGEFPVLVSVMTGAM
                     IFTSEMMKRLNFKLNVDYVDVSSYEESSESTGKVKLIQDLSHDIKDRPVLIMEDIIDTG
                     HTLKYLVALFANRGAKSIEICSLLDKPDRREVDVEADYVGFKVPNEFIVGYGLDFDGLY
                     RNLPYVGVLKRSVYEK"
     CDS             1418..2437
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053:beta-lactamase (Score: 118.6; E-value: 5.2e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg27_7"
                     /transl_table=11
                     /translation="MKKVNLYIFLTLCSFAIFLLTTPSKVKAEVVDKQTQHQLQDYMKD
                     HHINGVMLVNGKDGKPVAIENHETTNKDQIVKADRLFPTASLQKIVTGTAVYQLRQKKQ
                     LAWDTSLSKYYQQIDGSKDITIRELMNHTSGLINNDRPFEPLRGQKAQIAYMLKHLKYD
                     HTHTWDYQDVDYEILAAIVSKQTHQSYNAYIRKNFAKPLHLHQIKDFSEVSKKEIPQPM
                     DPTVDWHRVTVTTSSDFGAGNLFISPNDYWKFVYNEVLKDPKMINEYYHQAQHQEVAYF
                     GGVYFDGDVIRANGSIPGYNSCFVADYKTKRMIMLFSNNIDYLKLKAASDDILHNYME"
     CDS             complement(2505..2867)
                     /locus_tag="ctg27_8"
                     /transl_table=11
                     /translation="MAEGYARIFLKDKYEIQSAGLEAHGVNPLAIEVMAEDNIDISHQY
                     SKTIDPHYFKTANLIVTLCGDAKDRCPVIAPSTHSIYWPLPDPAQATGTPEQQLQIFRQ
                     VRNEIKQRILALASNP"
     CDS             complement(3253..3747)
                     /locus_tag="ctg27_9"
                     /transl_table=11
                     /translation="MALGTYQQVKDALKNFGITDYTVIDHPATHTTEEADAYIAGHEGV
                     RTKAMFLKGKKKNFYMVIMDDKKPMDFHEFMALTGAKRVSMARPEYLQEQLGLAPGIVS
                     PFGLLNNEAHNVKVYFDKDIVDEPIQTFHPNENTHTIFIKTDDMFKFLKPIDFEPEIID
                     L"
     CDS             3962..4252
                     /locus_tag="ctg27_10"
                     /transl_table=11
                     /translation="MLSYDREVITMSSKVQVNIDPELKQSAENIIKEIGLTPTAVINGM
                     YKQIVATGKIPLSFSLTPKQRTELELREVSKKIPVREVKTKEELEEFFNED"
     CDS             4242..4568
                     /locus_tag="ctg27_11"
                     /transl_table=11
                     /translation="MRTNQIYTAYVSWGLDGKRRPVLIVEDKNKNVFCYRITSKYKNKS
                     ERIKKNYFPLMDWKIEGLDKQSYVDVGDIIKLSKEHVSFRLIGELSTHDIEALVEFIRN
                     RYEI"
     CDS             complement(5001..7160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 280.8; E-value:
                     3.8e-85)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_12"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.2e-39, bitscore:
                     124.7, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 6.4e-290, bitscore:
                     954.4, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYNFRRHYINQVDEADCGVAALAMILHNYGSKISLATLRKFTKTT
                     TDGTTALGIVKAAEKLKMDVEAYQADASLFDSKDVIYPFIAHLIKKDSGLLHYCVVFKS
                     SKKHIFIADPDPNIQVKRIPKVNFFEEWTGIAIFAKPGKNYKAIQEKIPTFKRLCRPLF
                     QQKSLLCGIITAAFIVTFLNILNSYYLQTLLDTLIPNKLQDPLAIISIGLLFAYLFNTL
                     FTFSRDYLLAILGQRLSKIIILNYIKHVLKLPMAFFSTRKTGDILSRFTDANKVIDALV
                     SSIISIFLDATILIIIGTVLALQDIRLFGITMLVIPIYSLLIFSFTSNFRKLNQKEMES
                     NATVSASIIEDIRGIETIKSLNCEEVRSNKITNEFNDFLHKSLVHTRLNNIQQGLKTFV
                     QLSLNLIILWVGANQVIKNELSIGQLMTYNALLVYFTTSLQNIINLQPKIQSAQVANNR
                     LNEIYMVKDEFENTTKHNHSLKNGTIELKNVSYSYEYNSPILQNINLKIKSGEKMTIVG
                     LSGSGKSTLMKLLVNYFDVSNGEILINNLNILNISKKQLRSFINYVPQIPYTFSGTIKE
                     NLLLGNRTTITEKDIVTACKTAMIHDDIMHLPLGYDSKLDENAATFSGGQKQRLTIARA
                     LLSPAKVLIFDESTSGLDVLTEEKLIKNLMALSSKTIIFIAHRLSIARITNNITVIDNG
                     KIIERGSHEELLKNKSLYFNLMQTQ"
     CDS             complement(7172..7945)
                     /locus_tag="ctg27_13"
                     /transl_table=11
                     /translation="MEYHLIICDDDRTQAKNIATLLKMSSIILEEQDIHPTIDLIATDA
                     ESVLDYLEFNSDLNNIIAFLDIQLDENSNSKGGLDLAQKIKTLNEKAQIIFITTHEELA
                     FLTFQRRINPLDYITKTTSQRDLQRRLTETLELAIRKLNEFNYIKKNTFSYKVGTRIIN
                     VNFSNILYISTTKFPHKLKIVTSNGQGEFSGDIKTIEQNYSMFFKASQSSLINLQNVET
                     INTKKRLIKFSNNDCLNYSRSRAKELNNLYKNLTC"
     CDS             complement(7958..9220)
                     /locus_tag="ctg27_14"
                     /transl_table=11
                     /translation="MNFYLQILTSLFSIVIDYFLFLFLLRKKLFITDIWFLLSTFIIIF
                     IIDGLGYIGAYFSPLLEAFLLYLYYKKKTPKYLLISALLLVSLNSILIDFCTYVIGNFF
                     SISINYQILISITLYFSSFIILRIYNPIQYFQNDKSSINLWILFYLFITLNIAGFIIIT
                     IPSFTPSFIAIFCLLILQCIFTIFIYKANKQIQQKKLNLQEKKDLLFLIQNLEESQSRL
                     RRFKHDYQNLLNSLKLSALSGNNLELLEKLEKYSKERLGKDSLWQFQDTKNIKDDVLRS
                     IFISKLNSIYQKDIKYKFECVNKVTKLPKIDLFDLTRIIGIAYDNAIEECEQLKKGGIN
                     NVYIYSMLYQPTPRKLEFEIKNSCNPNIDIGNITAEGVSNKVNHHGLGLATVQKTIAKY
                     NNAFTSYSIEDESFTLIISFE"
     CDS             complement(9238..9420)
                     /locus_tag="ctg27_15"
                     /transl_table=11
                     /translation="MLGDGIMQSYKKLSTKQLATTIGGNIQQQSSQMVSLQSFGRITDK
                     DYTYTIYKKLKGIFH"
     CDS             complement(9438..9587)
                     /locus_tag="ctg27_16"
                     /transl_table=11
                     /translation="MGCLWLLLLGTETNKVNIFQNSYKQLPSLQNLSAIYPLLNFTDLK
                     TRSC"
     CDS             complement(9544..10062)
                     /locus_tag="ctg27_17"
                     /transl_table=11
                     /translation="MVKTKLFKRNKLMNKLFQWFYNMPKLTNQDNKDYMAKISLNIAVS
                     LFLFNLVAVLISFFIVTTTENYELSFNILAGALLIFTVYIVGGYSIYAKRKINRVVTHD
                     NTHIVKNSFASAVYITLIIYLLNSLTNALSFHTSLISELKNPMSYIIPTVIGIIYGVLM
                     ALITWYRNK"
     CDS             10229..10435
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_18"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.3e-16,
                     bitscore: 51.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLDNSQLKMILGGKNSWQQNVWGVARSTAAGAGLGAAICGPGC
                     GFVGAHYGAIVWAGTTGATHGFH"
     CDS             10462..10650
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg27_19"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.1e-10,
                     bitscore: 32.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLKYNQLELIIGGNRWGNATIGAMNGAKYGVKLCRPGGPWAMG
                     GCGLVGAGIGGYVGYRF"
     CDS             11345..11641
                     /locus_tag="ctg27_20"
                     /transl_table=11
                     /translation="MVEILIKTVAGRASPFDCKVKRTTNPATGHALRITVVKSGTPVIP
                     NNNKIVVPRIGKKIFLTKRLPQSAVGNLIFLILRLARLLPMTIIDSGVNAGLV"
     CDS             complement(11743..11886)
                     /locus_tag="ctg27_21"
                     /transl_table=11
                     /translation="MGVPLAQGLFGSVGVFYAVASMIDFNVMSWTQGIGIFQKRQPHDW
                     RT"
     CDS             12185..12436
                     /locus_tag="ctg27_22"
                     /transl_table=11
                     /translation="MTTWLKICPIDIASLPSVKHPDDKKKIYYSLTSNGKKVAKVHDQM
                     HETIKTKLVDKLTAKYSMDELNIVANFLNDLYRLEQKF"
     CDS             12533..13213
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 212.2; E-value: 1.1e-64)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg27_23"
                     /transl_table=11
                     /translation="MKKAVIMLVEDEESLASFLITELELEGYEVIWAKDGREALEIFKE
                     KDITLILLDWMLPIYDGLTVLRRIRQSSNVPIIMITARSQTSDISMALDQGLDDYITKP
                     FEIEELLARIRVVLRRLGQKKAEKYDYKFRPFEINLLKHQFMVDGKRVHLTPKEFSLMV
                     ALIKEPGVVQTRDDLLNEIWGYDFDGQTNTVDVYIRALRNKLGKYRDLIKTVRGIGYVL
                     GDEQ"
     CDS             13210..14541
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 181.5; E-value: 6.1e-55)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg27_24"
                     /transl_table=11
                     /translation="MSNTHPVTASRQLTRLFLMLFTVILVIINLLFVVTATNLIYRYAD
                     DQAEEVIETIEEDWPENQNRETFLNAYVARQDDDAIEITDGKREYTSPKAHKIFKRIDQ
                     RNLAIKNLQLTRHGVYYLRQQKIDHNRIVKVAINVDDLIKLTGWLLIVTLLINLAISII
                     ALPIIHRLARRWTRPLTNLDNEIDAITPQSNRLQTLTVPQQPLEVRKVAQSFNHLLGRQ
                     YRTMQREKEFIANASHELKTPLAGILGHVNLIRRHGDKHPELIGKSLKYIDQEAQRMSQ
                     LINELLILEGHQTKKLTEINLSKIIFAEVESLQGAYQQKFITDLNPNISYRITKGDFQS
                     LVHNLLENAAKYSPTDSIIDVLLTTDDRHIILRVADQGRGIAKENREKVFERFYREDES
                     HSNKIAGSGIGLAIVKMIIEKYHGKITIRDNEPSGTIFTVYLPK"
     CDS             14646..15296
                     /locus_tag="ctg27_25"
                     /transl_table=11
                     /translation="MTEKIEKRQDQQPKPDKKKARKFPKMTKKVLITACVCGGLVLGAG
                     GIAGVAAMDGYHAQIEAAVKHEKLANKSDIKINQQAAIDQFNKKYPDKHLNEVELESDK
                     GKYVYKVKGFDNTNEYKVKANAKDGKLISNKSEKLDQNEKEYTLDPGKAISRDEASQIA
                     EKAAKKGSAIEWKLEQEKENQAVWEVKVKDGRTVKEVKIDAGSKKILEVETDH"
     CDS             15314..15508
                     /locus_tag="ctg27_26"
                     /transl_table=11
                     /translation="MKVACEGFYYNFMFNDDFRDIGAYSFLSKYQKREKIPPGVALLLF
                     KMSILRGIVRLQFLLIDFI"
ORIGIN
        1 gggactttaa aatatttttt gtttaactga ttaataagtg catgcaaatc atcagtgttt
       61 ccttctaact ggataaagca agagaatcct ttactttgct tgagtgcaaa ttgatccaga
      121 tattttccaa gcacttctgc taagaggaca caacaagtac cgataacccc gatgctatat
      181 aaaccactac cataagcaag gccgattgca ccagtaaccc agatccctgc tgcggttgtt
      241 aaaccatcaa ttatttgatc atgacgatta ataattgttc cagcacccaa aaaaccaatt
      301 ccgctaacaa cttgagctgc aatccgcgat gggtcaacat tccaattact atgagtaatc
      361 ttcattaaat cgaaaaaacc atattttgaa ataatcatga ccattgctgc ccccacggca
      421 attagggcat gcgttcgaat tccagccatt ttagccttgc tttttcgctc aaaaccaatg
      481 atcccaccac ataaggcagc catgagcatt cgtaaacacc agtcaagcct aagcaacgat
      541 tacccctcct ttaccaaaaa tcaattatta tcaattttat taacctaact gtactatatc
      601 gcgtttaggt gtttaaagcc aaaaagaaag ctgaacgaaa tgaaaatttc cttcagcttt
      661 ttaactattt ctcatataca gaacgcttta gcacgcccac atatggaaga ttgcggtaga
      721 gaccatcaaa gtctaagccg tatccaacaa taaattcatt gggaacttta aagccaacat
      781 aatcggcttc aacatcaact tcacgccggt ctggcttatc gagtaaggag caaatctcaa
      841 tactcttagc gccgcgatta gcaaaaagag caacgagata ctttaatgta tgaccagtat
      901 caataatgtc ttccataata agaactggcc gatccttaat atcatgggaa agatcttgaa
      961 ttaatttaac ttttccggtg gattctgaac tttcttcata actagaaacg tcgacataat
     1021 caacgtttaa cttgaaatta aggcgcttca tcatttcgct agtgaaaatc attgctcctg
     1081 tcattacgga aactaaaact ggaaattcac cttggtattt ttcagtaagg gtattggcaa
     1141 gttcatctaa gcgttggttg acttgatctt gagtatataa aactttttcg acgtcgttat
     1201 tcattctagc tctcccttga taatgttcgt tatttacgaa ctatttttgc ggtttttatt
     1261 tattgacgtt agaattttaa cataaatcga atgaatttaa agtgttttag caagaaaaat
     1321 cagatttttg ttctgctttg taagaagagg cataaaattt gtataataca ggtagatatt
     1381 ttttgaaaac ggatgcctgg aagggatact tataattatg aaaaaagtta acttatatat
     1441 ttttttgacg ctttgttcct ttgccatctt cttattgacc acgccatcaa aggtaaaggc
     1501 agaagtagtt gacaaacaaa cgcaacacca acttcaagat tatatgaagg accatcatat
     1561 taatggagtg atgctagtta atggcaaaga tggaaagcca gttgccattg agaatcatga
     1621 aaccacgaat aaggatcaaa tcgtaaaggc ggatcgacta tttcccacgg catcgcttca
     1681 aaagattgta acgggaaccg ctgtttacca attaaggcaa aaaaagcaat tagcttggga
     1741 cacttcgcta agtaagtatt atcagcagat tgacggtagt aaagatatta cgattcggga
     1801 attaatgaat cataccagtg gcttgattaa taatgatcgt cccttcgaac cacttagagg
     1861 tcaaaaagca caaattgctt atatgcttaa acatctcaag tatgatcata cgcacacgtg
     1921 ggattatcag gatgttgatt atgaaatctt ggcagcgatt gttagtaagc aaacgcatca
     1981 aagctataat gcctatattc gaaaaaactt tgctaaaccg ctccatcttc accaaattaa
     2041 agatttttct gaggtttcca aaaaagaaat tccgcaacca atggatccaa cagttgattg
     2101 gcaccgggta actgtaacga cctcctcaga ttttggagcg gggaacttat ttatatcacc
     2161 aaacgattat tggaagtttg tatataatga ggtcctgaaa gatccaaaaa tgattaatga
     2221 atattatcat caagcccagc atcaagaagt ggcctatttt ggtggggtct actttgatgg
     2281 ggatgtaatc cgggccaacg ggagtattcc gggctacaac agttgctttg tcgccgatta
     2341 caagacgaaa cgaatgatta tgctgttctc taataatatc gattatctaa aattaaaggc
     2401 agcttcggat gatattctcc ataactatat ggaataacga taaatgcctt ctgagtaaac
     2461 aaatgagttt tgctcagaag gcatttttag atattaatat aattttacgg gttgcttgct
     2521 aaggctaaaa tccgctgctt aatctcattg cgtacttgcc ggaaaatttg caactgctgt
     2581 tcaggagttc cggtggcttg tgctggatct ggcagaggcc agtagatact gtgcgttgaa
     2641 ggagcgatga ctgggcaacg gtctttggcg tctccgcata aggttacaat taaattggcg
     2701 gtcttaaaat aatgaggatc aatcgtttta gaatattggt gactaatatc gatattgtct
     2761 tctgccatta cctcaattgc tagggggtta acgccatgag cttcaagacc agcactttgg
     2821 atttcgtact tgtctttcag aaaaattctt gcatatcctt ccgccatttg actgcgacaa
     2881 gaatttccag tacataagaa ataaatttta ttcattttag taatatctcc tgggataaaa
     2941 ttaggatcaa gtaggctgag ggactagaga gaagcagaat tactgatata ataacatgaa
     3001 aaagttagga atttaagttg aaaactagta aaagtgaaca cgagcttaaa atagacttat
     3061 atattgcttg ttacttattc ctaataggta cgttatgtca cagtgtaatt tcctgacggg
     3121 ggatcacctt atatctgaag gtggccctgt tttttacttg aacttatttg ctattagtga
     3181 gaacattaca agataaaaaa actccccccc aaaaaaagag ggagctaatc gcgataagta
     3241 atcgactggt ggttacaagt caataatttc tggttcaaaa tcaatcggct tgagaaattt
     3301 aaacatgtca tctgttttaa taaaaattgt atgagtattt tcattgggat ggaaagtctg
     3361 aattggttcg tcgacaatgt ccttgtcaaa atataccttt acattatgag cttcattatt
     3421 taggaggcca aatggtgaaa caattcctgg tgctaagcca agctgttctt gcagatattc
     3481 cggtcgagcc attgaaaccc ttttagctcc agttagggcc ataaattcat gaaagtccat
     3541 tggtttttta tcatccataa taaccatata gaaattcttt ttcttccctt tcagaaacat
     3601 ggctttagtg cgaacacctt catgaccagc gatatatgca tcagcttctt cggtggtgtg
     3661 agtagcaggg tgatcaatca cagtataatc agttattccg aaattcttta gggcatcttt
     3721 aacttgctga taggttccta atgccataat ttcgctcctt aattaaattt tttgtcatga
     3781 aacgcttaca ttaattataa agcaaattaa gcgattaaat gagccaatat tttttctgta
     3841 aaacttgttt caattaatgc tagggatcga acttaatatt ttttatggaa gaaattttaa
     3901 ttgaagcctt tgttgcttat taggaaatgt catgatgatt cttatatttt ataatcacaa
     3961 tatgttatca tatgatcgtg aggtgattac aatgagttcg aaagttcaag taaacattga
     4021 tccagaatta aaacagtcag cggagaatat tataaaggaa attggtttaa ccccgacagc
     4081 tgtaataaat ggaatgtata aacaaatagt tgccacaggg aaaatccctc ttagtttttc
     4141 tttgacacca aaacaaagga cggaattgga gttaagagaa gtatccaaga aaattccagt
     4201 tcgagaagtt aaaacaaaag aggaacttga ggaatttttt aatgaggact aatcaaattt
     4261 atactgctta tgtatcttgg ggattagatg gaaaaaggcg tccagttttg atcgtagaag
     4321 ataaaaataa aaatgtcttt tgttatagaa taacaagtaa atacaaaaac aaatctgaga
     4381 gaattaagaa aaattatttt cctcttatgg attggaaaat agaagggctt gataagcagt
     4441 catatgttga tgtgggagat attattaagc tttcaaaaga acatgtgtct tttagactta
     4501 ttggagaatt gtcaacgcac gatattgaag cgctggtaga atttattcgc aatcgatatg
     4561 agatatagaa acaaaaacgt cgcagaaaaa attctgtggc gttttgtttt gcaacttgcg
     4621 aggaaattaa agcgtaaacg catagagtca cagtaaatta ccacgaccct atgcgttcaa
     4681 gtttcagtta actgtaacca gaccactcca tcgctttagt caggtcgatt cgatctttcc
     4741 cagttgcgat ccaagaaata ttttgacgat tgcggtaatc aaggtaatct tttgtaactt
     4801 gttcactcgt aataatttag ataaaaaagc ctcttttgcc ttaagatgta ggtgttcgag
     4861 ccaaagtcaa taagggaaaa gaggtaataa gaatatgact aataattaaa caagttagtc
     4921 ataattaaaa gattatatgg ctattgtata agctaaggag gcttaatctt tatgcaaaat
     4981 tgaataaaaa tagtctctat ttattgtgtt tgcataagat taaaatataa cgatttattt
     5041 ttgaggagtt cttcatgaga accccgttca ataatcttac cattatcaat aactgtaata
     5101 ttatttgtaa ttcgagctat tgaaagacga tgggcaataa agataattgt ttttgaagat
     5161 aatgccatga gatttttgat tagtttctct tctgttaaaa catcaagtcc actagtagat
     5221 tcatcgaaaa tgagtacttt tgctggtgag agtaatgctc tcgctattgt aagtcgctgc
     5281 ttctgccctc cagaaaaggt tgctgcattt tcatctaatt tactatcata tcccaacggt
     5341 aaatgcatta tatcatcatg tatcatagcg gttttacatg cagttacaat atctttttca
     5401 gtaatcgtag tgcggtttcc taataataag ttttctttaa tcgttcctga aaatgtataa
     5461 ggaatctgtg gcacgtaatt aataaaagaa cgtaactgct ttttagagat atttaaaata
     5521 tttagattat taataagaat ttcaccattt gaaacatcaa aataatttac taataatttc
     5581 atcaaggttg atttaccaga gccacttaga cctacgattg tcattttttc gccagactta
     5641 atttttaagt taatattttg taatatagga gaattgtact cgtagctata agaaacattt
     5701 tttaactcga ttgttccatt ttttaatgaa tgattatgtt tagttgtatt ttcaaattcg
     5761 tctttaacca tgtatatctc atttaaacga ttattagcaa cttgcgcact ttggattttg
     5821 ggttgtaggt taatgatgtt ttgaagggaa gttgtaaagt aaactagtaa tgcattatag
     5881 gtcattaatt gtccaattga taattcattt ttaataacct ggttagctcc aacccataaa
     5941 atgataaggt taagcgaaag ttgaacaaaa gttttgagtc cttgttgtat attatttaat
     6001 ctagtgtgga ctaatgactt gtgtaagaaa tcattaaatt cgttagtaat cttgttagaa
     6061 cgaacttctt cgcaattaag agatttaata gtttcgattc ctctaatatc ttctataatt
     6121 gatgcactta ctgttgcgtt actttccatt tctttttggt ttagtttcct aaaattacta
     6181 gtaaatgaaa aaattagcag agaataaata ggaataacaa gcatagtaat tccgaataat
     6241 ctaatatctt gtaaagcaag aactgtacct ataattatta aaatagtggc atctaaaaag
     6301 atagatataa ttgaactgac aagagcatca attactttat tcgcgtcggt aaaacgagat
     6361 agaatatcac cagtctttct agtagagaaa aatgccattg gaagttttaa aacatgcttt
     6421 atatagttta ggataataat tttagatagt ctctgcccta gaatagctaa taagtaatcc
     6481 cgagaaaaag taaatagagt gttaaaaaga taggcgaaca atagtccaat gctaataatt
     6541 gctaaaggat cttgaagttt attaggaatt aatgtgtcaa gtaaagtttg tagataataa
     6601 gaatttaaaa tattaagaaa cgttacaata aaagctgctg taataattcc acaaagtagg
     6661 gatttttgtt gaaaaagtgg tcgacataat cttttaaaag tggggatttt ttcttgaata
     6721 gctttatagt tcttacctgg ttttgcaaaa atagcaattc cagtccattc ttcaaaaaaa
     6781 ttgaccttag gaatacgttt aacttgtata ttaggatcag gatcagcaat aaaaatatgt
     6841 tttttggaac ttttaaaaac aacacaatag tgaaggagcc cactgtcttt ttttatgaga
     6901 tgagcaataa aaggataaat tacatctttt gaatcaaata aactagcatc tgcttgatac
     6961 gcttcaacat ccatttttaa cttttctgct gcttttacaa tcccaagtgc agtagttcca
     7021 tcagtagtgg tttttgtaaa ttttcgcaga gttgctaatg aaattttaga gccgtaatta
     7081 tgaagaatca ttgctagtgc tgctactcca caatcagctt catcaacttg atttatatag
     7141 tgtcttctaa agttatacat aaagtgcctc gttaacaagt tagattttta tatagattat
     7201 ttaattcttt agctctgctt ctagaataat ttaaacaatc attgttagaa aacttaatga
     7261 gccgtttttt agtattaatt gtttcaacat tttgtaagtt aattaagcta gactgagaag
     7321 ccttgaaaaa catagaataa ttttgctcaa ttgttttaat atcacctgag aattcccctt
     7381 gaccattaga tgtaacgatc tttaatttat gagggaattt tgtagtagag atataaagga
     7441 tattactgaa gtttacattt ataatccttg tgccaacttt ataactgaat gtattttttt
     7501 taatatagtt aaattcattc agtttcctta tagctagttc tagggtttcg gttagccgtc
     7561 tttgtaaatc tcgttggctt gtggttttag ttatataatc caacggatta attcgacgtt
     7621 gaaaggtgag aaaagctagc tcttcatgcg ttgtaataaa gattatttgt gctttttcgt
     7681 taagtgtttt tatcttttga gctaaatcta gaccaccttt tgaattggaa ttttcatcta
     7741 actgaatatc taaaaaggca ataatattat ttaaatcact attaaactca aggtaatcta
     7801 aaacactctc tgcgtccgtt gcaatcaaat caatggttgg atgaatatct tgttcttcaa
     7861 gaataattga tgacatttta agcagggtag cgatattttt tgcttgagtt ctgtcatcat
     7921 cgcaaattat taaatgatat tccatttttt gtcctttcta ttcaaaagaa attataagag
     7981 taaaagattc atcttctatg ctataagaag taaatgcatt attatatttt gcaatcgttt
     8041 tttgtactgt agctagtcct aaaccatggt ggttaacttt atttgaaact ccttctgcag
     8101 tgatatttcc aatatcaatg ttaggattac acgaattctt tatttcaaat tctagttttc
     8161 taggtgtggg ttgataaagc atggaataaa tatatacgtt atttattccg ccttttttaa
     8221 gttgctcgca ttcttcaatt gcattatcat aggcaattcc gattattctg gttaaatcaa
     8281 ataaatctat tttgggtaac ttggttactt tatttacaca ttcaaatttg tattttatgt
     8341 ctttctggta tattgaattt aatttactaa tgaagatact tcgtaaaaca tcatctttga
     8401 tattttttgt gtcttgaaat tgccaaagcg aatcttttcc taatctttct ttcgaatatt
     8461 tttctaattt ttccaatagt tctaaattgt taccacttaa agcactaagt tttaaactat
     8521 ttaataaatt ttgatagtcg tgcttaaagc gccttaacct agattggctt tcttctagat
     8581 tttgaattaa gaatagtaag tctttctttt cttgtaaatt tagctttttc tgttggattt
     8641 gtttattagc tttgtagata aaaatggtga aaatacattg taaaattaat agacaaaaaa
     8701 tagcaataaa tgatggcgta aaacttggaa tagtaatgat tataaaacca gcaatattta
     8761 aggttataaa taaataaaat agaatccaca aattgatgga actcttatca ttttgaaaat
     8821 attggatagg attatagatc cttagaataa taaagctaga aaaatataaa gtaatgctaa
     8881 ttagaatttg gtaattgatg gaaatactga aaaaatttcc tataacataa gtgcagaaat
     8941 ctataagaat tgaatttaag gaaaccaata ataaagcgct aatcaataga tatttaggcg
     9001 tttttttctt gtaatagaga tataaaagaa aggcttcgag tagtggtgaa aagtaagcgc
     9061 caatataccc aaggccatca atgataaaaa taataataaa agtgcttaat agaaaccata
     9121 tatcagtaat aaaaagcttt tttcgtaaaa gaaaaagaaa taaaaagtag tcaatcacta
     9181 tagagaacaa cgaagtaagt atttggagat aaaaattcaa agtaattacc ttctaaatta
     9241 gtgaaaaatg ccttttaact ttttataaat tgtatatgtg taatctttat cagttattcg
     9301 tccaaagctt tgaagagata ccatttggct agattgttgt tgtatattac cacctatagt
     9361 agttgctaat tgttttgttg aaagtttttt ataactttgc ataattccgt ctcctaacaa
     9421 tttttaatag ttttattcta acaagatcta gtttttaaat cagtaaaatt caaaagtggg
     9481 taaatagcac tcaaattctg taaagaaggt agttgtttat atgagttttg aaaaatattt
     9541 accttatttg tttctgtacc aagtaataag agccataagc accccatata taatcccaat
     9601 tacagttgga attatataac tcatgggatt ttttaattcg ctaataagtg aagtatgaaa
     9661 actaagagca tttgtaagag aattaagtaa ataaataatc agtgttatat atacagctga
     9721 ggcaaaacta ttctttacaa tatgtgtgtt atcatgagtc acgactcgat taattttacg
     9781 ttttgcatat atagaatagc caccaacaat ataaacagta aagatcagta acgccccagc
     9841 taaaatatta aaagacaatt cataattctc tgttgtagta acaatgaaaa aggaaataag
     9901 gacagcaacg aggttaaaaa gaaataagct aacagcgata ttaagactaa tcttcgccat
     9961 ataatcttta ttatcttgat ttgttaattt gggcatatta tagaaccatt gaaaaagttt
    10021 attcattaat ttattccttt taaaaagttt ggtttttacc atagcataat ttatcttttt
    10081 taataatttc cttctaattt tagtggaatt ttagcatatt aggatgttga agcaggatat
    10141 gagtgtaatt tgtacaaatt agaagtttcc atttagcagt cttaatttac tttatgctta
    10201 aagtatagaa attaaggagg taattgttat gaaaaaatta gataattcac aattaaaaat
    10261 gattttaggt ggtaaaaatt cctggcaaca aaacgtctgg ggagttgcgc gttctacagc
    10321 agcaggtgca gggcttggtg cagctatctg tggcccaggt tgtggatttg ttggggcaca
    10381 ttatggtgct attgtttggg cagggactac tggtgctacc catggctttc actaaaaatt
    10441 aagaatacga ggagaattgt aatgaaacaa ttaaaataca accaattaga acttattatc
    10501 ggcgggaatc gttggggaaa tgcaacaatc ggcgcaatga atggtgccaa atatggagtg
    10561 aaactttgcc gtcctggtgg tccatgggcc atgggaggat gtggtcttgt tggtgctggc
    10621 atcggcggct atgttggata tcgtttctaa aataggagga attctttata aaaaattttt
    10681 tgtttgatcc attatatttt tttgctatag cttttatata tttaatattt gattacaatt
    10741 ttggcatgat atcgatgtca atcttttgtg gactttcgtt attaattagt aatctaggaa
    10801 agaaattttt atatctgcaa gcactattgt tcataatata tggattatta ctttttatag
    10861 ttcatccaag cacatggata gtttctgtaa ttttgatctt aattggaata gttttcttta
    10921 tattttattt tagaggctaa actggcttct agaagaagac tggagtaaaa ggtatgatcc
    10981 cagttggata ttggaatcat acctttttat cttgcacttt aactttataa atttcattac
    11041 gcaagactct tcgttacttt agtttaaata ctcaaagtat atgctagagt tcttgcgttt
    11101 tcttgttttt aaagcaaaaa cgcatagaat cacagtaatt taacccgatc ctatgcattt
    11161 aattttcaat tgtaatatat ggtttattca tttataaagc ctccttaata tctaattcca
    11221 tcatagatta aggaggctgt tatttgaaat gcttattata tttaatactt tattcaaaga
    11281 ttgtatatac cattaccaca aactagcaaa ccaatagact aatggaatag ttactaaact
    11341 caaaatggtt gaaatactca ttaagacggt tgctggccgt gcatccccat ttgattgtaa
    11401 ggtaaaaaga acgactaatc ctgctactgg acatgcacta agaattactg tggtgaagag
    11461 tggaacaccg gtgattccta ataataataa gatagttgtc cctagaattg ggaagaaaat
    11521 attccttacg aagagacttc cccagagtgc agttggtaat ttgatatttt taatacttag
    11581 attggcaaga ttacttccga tgacaatcat tgatagtgga gtaaacgctg gactggtgta
    11641 atcaataaaa ccagcaatta attttggcaa ccgaaaagaa ctaatgaata ggaagaggcc
    11701 aataatagcg ataatattag gatttaaaat aattttcttt aactatgttc tccaatcatg
    11761 aggctgtcgt ttttgaaaaa ttccaattcc ctgggtccat gacatgacat taaaatcaat
    11821 cattgaggcg acggcataga agacccccac acttccaaaa agtccttgtg ctaatggaac
    11881 gcccataaaa ccattgttag aatagatact tccctaagtt gcaatttgac gaatattttg
    11941 gtcattttct ttatgaaaaa gtagttttgc aatcaaaatt gaaacaaaat aggtcagaaa
    12001 gacaccagca attaatagta ataattgata aaatcgtgat cgcgaaaacg gctgttcaaa
    12061 ggccttaata attacgattg gcgataaaaa gtagagtgta atatttgtta ggtcattaat
    12121 tgattgcgga tggagaaatc cgagcttttt aataactgcc cctaaaagca ttagtaagaa
    12181 aataatgacg acctggttaa aaatttgccc aatcgacatt gcatcacttc cttcagtaaa
    12241 acatcctgat gataaaaaga aaatatatta ttcattaacg agtaatggga aaaaagtagc
    12301 aaaagttcat gatcaaatgc atgaaacaat aaagactaag ttggttgata aactaaccgc
    12361 aaaatattca atggatgaat taaatattgt tgctaatttc ttaaatgatt tatatcggct
    12421 tgaacaaaaa ttctaattac cagtaaaaaa gtttcatatg aaactttttt tatttgcctg
    12481 caatcaaaac agctaaaata gtatatagga caaagtaatt ggaggcaaaa taatgaagaa
    12541 agctgtaatt atgttagttg aggatgagga aagtcttgca agtttcttaa taactgaatt
    12601 agaactagaa ggatatgaag ttatctgggc caaagatggg cgtgaggcac tcgagatatt
    12661 taaagaaaaa gatataacct taatcttatt agattggatg ctcccaattt atgatggtct
    12721 cacagttcta cgccgaattc ggcaatcaag taatgtgcca attattatga ttacggctcg
    12781 tagtcaaact tctgatatta gtatggcact tgatcaagga ttagatgatt atattactaa
    12841 accgtttgag attgaggaac ttttagcacg aattagggtt gtattacgac gattgggtca
    12901 aaaaaaagca gagaaatatg attataaatt tagaccattt gaaattaatt tactgaaaca
    12961 tcaatttatg gttgatggca agcgggttca tttaacgcct aaagaatttt ccctcatggt
    13021 tgccctaatt aaagaaccag gagtcgttca aacccgtgat gaccttctta atgaaatatg
    13081 ggggtatgat tttgatggtc agaccaatac tgttgatgtc tatattcgtg ctttgcgcaa
    13141 caagttaggc aaataccgcg acttaattaa aacggtgcga gggattggtt atgtattagg
    13201 tgatgagcaa tgagtaacac acatccagta actgcatcgc ggcaattaac tcgtcttttc
    13261 ttaatgttgt ttacagtgat tttagtaatt attaatcttc tttttgtggt taccgccact
    13321 aatttaatct atcgttatgc tgatgatcag gcagaagaag tgattgagac aattgaggaa
    13381 gattggcccg aaaatcaaaa tcgcgaaact tttttgaatg cttatgttgc tcgtcaagac
    13441 gatgacgcaa tcgagatcac tgatggtaaa cgagaatata cctcacccaa agcccataaa
    13501 atttttaaac gaattgacca gcgaaattta gcaatcaaga atctacagtt aacccggcat
    13561 ggagtctatt atttacggca gcaaaaaata gaccataatc gaatcgtcaa agtagcaatt
    13621 aatgttgatg atttaatcaa attaacaggc tggctcttga tagtgacgct gttaattaac
    13681 cttgcaataa gtatcattgc tctccccatc attcatcgtt tagctcgccg atggacccga
    13741 ccattgacta atttagataa tgaaattgat gcaatcacgc cccaaagcaa tcgattgcaa
    13801 actttaacgg ttccgcaaca accattagag gtacgaaaag ttgcccagtc ttttaatcat
    13861 ttgctaggac ggcaatatcg tacaatgcaa cgcgaaaaag aatttattgc aaatgcatct
    13921 catgagttga agacaccact tgccggaatt ctgggacatg taaacttgat aagaaggcat
    13981 ggggataaac atccggaatt aattggcaaa tcattaaagt acattgatca agaagcgcaa
    14041 cgaatgagtc aattaataaa tgaactgctt attttagaag gacaccaaac caaaaaatta
    14101 acagaaatta acttatcgaa aattattttc gctgaagttg agtcactcca aggggcatat
    14161 cagcagaaat ttattactga tttaaatccg aatatatctt accggataac aaagggtgac
    14221 tttcaaagtc ttgtgcataa tttattagaa aatgcggcca aatattcacc aactgattca
    14281 ataattgatg tgctgttaac gacagatgat cgccacataa ttttaagagt tgctgatcaa
    14341 gggcggggaa ttgctaagga aaatcgggaa aaagttttcg aaagatttta ccgtgaagat
    14401 gaatcacact ccaataagat tgctggttca gggattggcc tggcgattgt caaaatgatt
    14461 atcgaaaaat atcacggaaa aatcacgata cgcgataatg aaccaagtgg gaccattttt
    14521 acggtttacc ttccaaaata aaaatgaaga tttctttatc atactttcac cggttcttgg
    14581 ttttagttga ccgattattt tgtagaataa aattaccaat taaagttaag aagggatgaa
    14641 taaaaatgac tgaaaaaatt gaaaaaagac aagaccaaca accaaagcca gacaaaaaga
    14701 aagcaaggaa gttcccaaag atgactaaaa aggttctgat taccgcctgt gtttgtggag
    14761 gacttgtgtt aggagctgga ggcattgctg gtgtcgccgc aatggatggt tatcatgctc
    14821 aaatcgaagc cgcggtgaaa catgaaaagt tagctaataa gagcgacatc aagattaacc
    14881 aacaggctgc aattgatcag tttaacaaga agtacccaga taagcacctc aatgaagtag
    14941 agctggaaag tgacaaggga aaatatgtgt acaaggtaaa gggctttgac aataccaacg
    15001 aatacaaggt taaagccaat gccaaggatg gcaaactaat ctctaacaag tctgaaaagc
    15061 ttgaccaaaa tgagaaggaa tataccttag atccaggtaa ggcaattagc cgtgatgaag
    15121 cgagccaaat tgccgaaaaa gccgctaaaa agggtagtgc gatcgaatgg aaattagaac
    15181 aagaaaagga aaatcaagct gtttgggaag ttaaagtaaa agatggccgg acagttaaag
    15241 aagttaagat tgatgctgga tcgaagaaaa tattagaggt tgaaactgat cattaataaa
    15301 atcccccgca tgtgtgaagg ttgcatgcga gggattttat tacaatttta tgtttaatga
    15361 tgattttcgc gatattggtg cgtactcgtt cctgtccaag tatcaaaagc gcgaaaaaat
    15421 acctcctgga gttgcacttt tattatttaa aatgtcaatc ctaaggggta ttgtacgtct
    15481 acaatttctc cttatagatt ttatttagtt cttttgttcg actacgggaa aatttgattt
    15541 tatcgccatt gataaacgtt acgattcggc tttttgtatt gattgattca atattttgcg
    15601 gattgatcag agctgattgt gatgccttaa aaaagaacga ataattctgt
//
