LOCUS       gnlProkkaBPLELJHN_43   12151 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BPLELJHN_43.
ACCESSION   gnlProkkaBPLELJHN_43
VERSION     gnlProkkaBPLELJHN_43
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 08:15:30
            Original ID  :: gnl|Prokka|BPLELJHN_43
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 68200
            Orig. end    :: 80351
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12151
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:7151]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7151
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..12151
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12151
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             1825..3012
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-387). E-value:
                     1.1e-72. Score: 237.0. Matches aSDomain:
                     nrpspksdomains_ctg38_44_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 273.7; E-value:
                     4.3e-83)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_44"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.1e-72, bitscore:
                     237.1, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3.9e-07,
                     bitscore: 23.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTKKEILNRLNNNFAKLTPGGIREFDYQVSAIPGIIKLTLGEP
                     DFNVPIAMKQAAIDSINANDSHYAPGNGTLALRQAIAHFMQDRYELEYDPENEIAVTVG
                     ATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKILGGIPIEVDTSNDDFVLTPAKLQS
                     ILEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTIKSTNLIVIADEIYSELVYGATHT
                     SIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQELMKSVSAIHAMLVTAASNPAMAAA
                     VAAFGTDEGKTATQEMKDAYEQRRDFVVNNLQKLGFELINPQGAFYVFAKIPEQYGNDD
                     LKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATSMENLTGALDNIAAFINKED"
     aSDomain        1933..2985
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg38_44_Aminotran_1_2.1"
                     /evalue="1.10E-72"
                     /label="ctg38_44_Aminotran_1_2.1"
                     /locus_tag="ctg38_44"
                     /protein_end="387"
                     /protein_start="36"
                     /score="237.0"
                     /tool="antismash"
                     /translation="IIKLTLGEPDFNVPIAMKQAAIDSINANDSHYAPGNGTLALRQAI
                     AHFMQDRYELEYDPENEIAVTVGATEGIFASLSTIINPGDEIIIPTPTFPFYMAVTKIL
                     GGIPIEVDTSNDDFVLTPAKLQSILEEHPNAKGLVLNYPSNPTGVTYTQDQIKALADTI
                     KSTNLIVIADEIYSELVYGATHTSIANYIPEQTLILNGASKSHAMTGYRIGFIAGPQEL
                     MKSVSAIHAMLVTAASNPAMAAAVAAFGTDEGKTATQEMKDAYEQRRDFVVNNLQKLGF
                     ELINPQGAFYVFAKIPEQYGNDDLKFATDLANEGKVAVIPGSFFGAGGQGYVRISYATS
                     MENLTGALDNI"
     CDS             3014..4009
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1072:dehydrogenase (Score: 299.5; E-value: 3.3e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_45"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 6.6e-53, bitscore:
                     172.1, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKILMTSVRDDEQTAINEYAKEHNIEIITTPKLIDDAVELTADV
                     DGLVIQQRSKVPADIYEKLHTNGLKQIATRTAGFDMVDIKKANENGLVVTNVPAYSPRS
                     VAEFALMQIFRLLRKTYRFDHQVAENDFRWFSDEQSTEIHTATIGIIGVGRIGGTLAKL
                     LHALGATVLGYDTNPRTDLDGIVQFVSKEELLKQADVVSLHVDLNPTSKGLLTANDFEV
                     MKPTASLVNASRGPVINTADLVAALKKGTIAAAALDTFEGEETVAATNRREKGLDDQPL
                     VKELHEMDNVILTPHIAFFTNLAVKNMVDISLDDVMTILNGEKSPHEITL"
     CDS             4077..4505
                     /locus_tag="ctg38_46"
                     /transl_table=11
                     /translation="MSKYKVTATKTTTGMQGSAGTRGFEITFDEPESTNTGMNPVEILL
                     ASFGACQAITAQALAKKRNFDLRAFWVTIEGDLGREDVADGKNVRKFTEIRYQPHLRSS
                     ESDEDIKKFLADVAAKCPVENTLTYGTKFVQDGFVKVD"
     CDS             4783..4968
                     /locus_tag="ctg38_47"
                     /transl_table=11
                     /translation="MKIHFNKDFWRDGFFYIYLLLLFLWIAPFSDGSLPLDEELLCIFF
                     IIFTIGSMLAIMFNKD"
     CDS             complement(5001..7151)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 332; E-value:
                     1.2e-100)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_48"
                     /sec_met_domain="Peptidase_C39 (E-value: 3.2e-39, bitscore:
                     127.2, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 2.1e-275, bitscore:
                     908.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKINYPHYVAQVDEADCGVASLAMILRNFGSVYPIAKLRDLARTT
                     KQGTTALGLVKAAKHLGLDVIPIQADISLFDDPEITYPLIAHVIKDDLLHYCVVFKANQ
                     DYIYVADPDPATKVQKMTRDEFDRLWSGVCLLFSPAKGYTPQKEPLAGLTTMFQQLTNY
                     KKDISGIVIAAMLITFISIVGSYYLQLIIDRFIPSKNINGLTILAGSLLVVYVFNSLFN
                     YLRDVLLTRLDQKLTSQISLRYIHHVYRLPMRFFSTRKTGEITSRFNDINKIIDALSST
                     IISMFLDVGVMVIIGIVLSLYDRSLFLTTISTIPIYVIIIYAFNKRFVKLDQEQMESNA
                     QLSSAIIEDLKGVETLKVLQLENIRYKNVEKQFADFLRKNLTYVKTKSFQDAIKMWIQY
                     GLVTIILFQGAVLVIQGRLSIGTLMAFNALLAFFISPLQNIINLQPKLQEAKVANNRLN
                     EVLQVDTEKSDTNSQDQTDLIGPINIQHVDYSYEYSRPILQDINLQIGCNDKLAIVGLS
                     GSGKSTLAKLLVGFYLPTQGQIEFNQHKTTEINLCDIRQYVHYLPQSPQLFSGTIKDNL
                     LMGLDREVSVEEIDNACKLALIYNDIQEMPLKYETKLDEEATVLSGGQKQRLTIARALL
                     TSARVLIFDESTSSLDPITEKRIVENLLSIEDRTMIFIAHRLSIAKKVNRVVVMRDGKI
                     IEQGTHQELLNHHQEYYNLWNA"
     CDS             complement(7428..7586)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_49"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTYRKLNFDELSKVSGGWSLSSQVNELVRDVVNSLNKWAQSCYAG
                     YKDSPFH"
     CDS             complement(7789..8556)
                     /locus_tag="ctg38_50"
                     /transl_table=11
                     /translation="MLKVIILENDDYQADYTERLVSQRKLINATPNSYDIELYLRTNDP
                     QEVIDSIKDEAYLAILDIELDNQLSGIDVAEQIRKRAEFAEIIFVTAYQEYLPYTVSRR
                     IEPFDYISKGKQIESIADRLRIDIDEAYARYQNYVSSNQKHHEKITYEPIRGVKRQVDL
                     EKLYYIESVKNTNRRLRIVGKDIRIEYHGELNQVDSKHLLKVNQSTLINPKAIQEFNRK
                     ERIVYFDANREIKVTVSYRKIKSLVDFLEKENH"
     CDS             complement(8564..9877)
                     /locus_tag="ctg38_51"
                     /transl_table=11
                     /translation="MIHLTVGQGLTSSILNIIEIILIYQLVTSDFSLGLVIIDFLAVLM
                     IIFFSIVFFMLGSLYPVLIVFYFWLVDRIKSNSYIVINSILAMCISIVMASLFDLVDHY
                     TYTFFLQGKTDIALLGWLIPINDLIITIVVAILAVKVVRPKLRWIRINFPRPIGLWQIT
                     AILFMLYVWLTAIAEKDGVANKYASLLLIMYLIIIVVCATGFINFVKSSQQTQRQQQII
                     DKYQAQIASANQLNQQYNEIRRERHDTRNMLLSVQGYIRDHKDKEAEKLLATFLQNDTV
                     EKHYGEIDNALDKIKISGLHNLIKEKAYKIVEKGIPFSFEVNAEIDELPGSEIKTARII
                     GILMDNAIEATFKQTKPYIQFALLKHSPEVYELVIANSIEQKLNINTALKFEHSTKEGH
                     QGIGLSNVTQLVENDDHYSFSAEVKDKVIMMTCFIQGK"
     CDS             complement(9874..10005)
                     /locus_tag="ctg38_52"
                     /transl_table=11
                     /translation="MLKKSYKFLSRKELSKVLGGWGYSLAFKSPRSWERAVLNWIKR"
     CDS             complement(10032..10196)
                     /locus_tag="ctg38_53"
                     /transl_table=11
                     /translation="MVDLDLETKKNLVIINLFYIGLIALYCILHAGPLNFLVFLGMLVL
                     ANIAEFVVK"
     CDS             complement(10320..11714)
                     /locus_tag="ctg38_54"
                     /transl_table=11
                     /translation="MQKLSIKQLIIITLGLLVLVMGLMTIHQRRHFNKNVKIDNVAVGG
                     LTAKQALKKLQDNPQTPKVYVNNDLVYTGKQPVAKFTQADEEKVANALHRQYTFFPSNK
                     DKNLLIKPQKFNQSVVPQVDQAVSQKVMELNNGRKAPINAYAVYENGQVQVRPAVGGTQ
                     YSLDGLHNQVEKELVQGEVKLKPIYKAPLSAKSKTVQNEKTKLEQIAKRDVTYQVQGKK
                     YHLTSADIITRATYQDGKYHFNTKVLGTKIDEINNQQATLGKPFEFKTHSGSVIKTTAA
                     GSYGWKISKKQAGKTLTNALIENKQTVNAKNDIYGKGYNQQGTGYNTTSNNGIGDTYAE
                     VSLADQHAWFYKNGKCVLSTDIVSGTNNKDNETPKGVWYIMYQQTPSVLRGLNDDGSKY
                     ASKVQYWSPFTDSGCGFHDASWRHDWSKQAYLAKGGGSHGCINMHPDVAGQAFSDLHKN
                     EPVVIY"
ORIGIN
        1 gctgggtgct ttgctgctaa gtgagcagcg gtcatatcga ttaagtcgat agccttgtca
       61 ggtaatgcgc gttgtggcat gtattgaaca gagtaatcaa cagcagcttg gagaacgtca
      121 tctggtaact ttacattgtg gtgacgttcg tacaagtcac ggataccttt aagaatagct
      181 acagtatcag ccttgcttgg agcattaaca gtaacagcat tgaaccgccg tgctaatgca
      241 gcatccttca taatagtgtt ccggtattca tcttgagtag ttgcaccgat aaccgttagt
      301 tcaccacggg ataatgctgg cttaataatg tcagacatac ccttggaacc actagaatca
      361 ccagttgaac cggcaccgat aatttggtga atttcatcga agaagaggat gatatttcca
      421 gccttcttga cttcatcaac caacttttgc atgttttctt caaagctacc acggtattga
      481 gtacctgctt caaggccaga aatatcgata ctgataattt ccttgtcctt gatagcagct
      541 ggtacatcgc cagaaacaat tgcttgtgct aatccttcaa caacagcagt cttaccaaca
      601 ccagcgtccc caactaatac agggttgttc tttgtccgcc ggcttaaaat ttcagctgtt
      661 tcttggattt ccttgttccg accaataaca gggtcaagtt catgttcacg agcttcttga
      721 gttaagtttc gacctaactt gtgtaagata ctgtccttac ctgcgttagg ttgagggcca
      781 ggttgcccac cttgttgagg atttgcaccg cctggcaatt gaccagttct acgatattca
      841 gcaaattctt ctggtgttac ttcacgacca ttgattaggt aacgccgatt atcagaattg
      901 aaaccattca tgccacccat taattgatta aagatgtcat tcatgtcgtt gtcaaatgga
      961 ttcattgggt tttgagccat atgcaatccc tcctcaatta aatataatat tttgttttct
     1021 aagtttcgta gtctaagtat tctagaagtt aaaagttaac gcatttaact tcctgtggct
     1081 acagcaaagc cacaatctca ttcgaggtaa tgctcttcta gttctttaag gacctcccac
     1141 atgctcttgt cctgagcacg agccaaggca tcaagatcac gcaggttaag cgaggtcgaa
     1201 ctagactgtg gtttgttaaa cgatttgtgt aaagtcgtgt agccgtaacc ggaacgcttg
     1261 gaaacttgat aaatggtcaa gtggttaact tccaaataat gtttgatgtc gatccgcatt
     1321 gctacccact tcctttacga ttaatattat atcacatttg tggagtaaaa caacaaaaaa
     1381 gacacgaaaa aataaaaaaa attgtagaat ataaatttaa tattaaatta aaggcggact
     1441 aataatcaca aacattttcg cactttatta tatttacatt tgtcatcaat aaataatttt
     1501 gtaattaata atttttctca atcaactctt gacaaaaatt aaaaaacaat tagaataatt
     1561 aataatcagt taatcaaaag gaggacacaa tgatgagcac tgcgacaatt cacttgaatc
     1621 aagcgtatgt cttctggttt agcgcgatta ccgtccgcta accagcagtg attttatcat
     1681 tgtgatgttc ccggatgacc cccaaacatc cgagagcctc ttttatactc attccaatct
     1741 gatcaagaag ccctggatgt ttttcctata gcattcaggg cttctttttt tctaaatcta
     1801 catattatat aggaggaatt tatcatgcca actactaaaa aagaaattct caatcgtctt
     1861 aacaataatt tcgctaaact cactcctggc gggatccgcg aatttgacta tcaagtcagt
     1921 gcaattcctg gcatcattaa actaacatta ggtgaaccag actttaatgt gccaatcgca
     1981 atgaagcagg ccgcaatcga tagcatcaat gccaatgatt cacactatgc tccgggaaat
     2041 gggaccttag cactacgcca agcaatcgct cacttcatgc aagatcgtta cgagctggaa
     2101 tacgatccgg aaaacgaaat tgctgttaca gttggcgcaa cagaaggaat tttcgcttct
     2161 ctttctacta ttattaatcc tggcgacgaa attatcattc caaccccaac tttccccttc
     2221 tacatggctg tcacaaagat tcttggtggg attccgattg aagttgatac aagcaacgat
     2281 gattttgttc tcacacccgc aaaactccaa agcatcctag aagaacatcc taacgcaaag
     2341 ggactagttc ttaactaccc ctccaaccca actggtgtta cttacaccca agatcaaatt
     2401 aaagcactag ccgatacgat taaatcaacg aacctaattg taattgcaga tgaaatttac
     2461 tctgaacttg tttatggagc tactcatact tcaatcgcta attacatccc cgaacaaacg
     2521 ctaattttaa atggtgcctc aaagtcacat gcaatgactg gttaccgcat tggttttatc
     2581 gctgggccgc aagaattgat gaaatcagtc agtgccattc acgcgatgtt agtaaccgct
     2641 gcttctaatc cagcaatggc cgctgcagtc gccgcatttg gtactgacga aggaaaaaca
     2701 gctactcaag aaatgaaaga tgcttatgag caacgacgag actttgttgt taataacctc
     2761 caaaaattag ggttcgaact gattaatcct caaggagcct tctacgtttt tgctaagatt
     2821 cctgaacaat atggtaatga tgaccttaaa tttgcgacgg atcttgccaa tgaaggaaaa
     2881 gttgctgtga ttcctggttc cttctttgga gctggcggcc aaggatatgt tcgaattagt
     2941 tacgcaacca gtatggaaaa tctaaccgga gctcttgata acattgcggc cttcattaat
     3001 aaggaggatt aacatgacaa aaatcttgat gactagtgtg cgggacgatg aacaaaccgc
     3061 cattaacgaa tacgcaaaag aacataatat cgaaatcatc acaacgccga aattgattga
     3121 tgatgctgtt gaattaacgg ccgatgttga tggactcgtg attcagcaac gtagtaaagt
     3181 tccggctgat atttatgaaa agctccatac caatgggctc aaacagattg caacgcggac
     3241 agctggtttt gacatggtcg acatcaaaaa ggccaacgaa aatggcttag tcgtgaccaa
     3301 tgtaccagca tattcaccgc ggagtgtcgc cgagtttgca ttaatgcaga ttttccggtt
     3361 acttcggaaa acttaccgct ttgaccacca agtcgccgaa aatgacttcc gctggtttag
     3421 cgatgaacaa tcaacggaaa ttcatactgc cacgattggt attattggtg ttggacgcat
     3481 tggcggaact ctggcaaaac ttcttcatgc attaggtgct accgttctag gatatgacac
     3541 gaatccgcgc actgacctcg atggaattgt ccagttcgtt tctaaagaag aattactaaa
     3601 gcaagccgat gttgttagtc tccacgtcga tttaaatcca acttctaaag gtttattgac
     3661 tgctaacgac tttgaagtga tgaaaccaac tgccagtttg gtcaatgcta gccgtggtcc
     3721 agtcattaat acagctgatt tagttgcggc cttaaaaaag ggaacaattg cagctgccgc
     3781 tcttgatact tttgaaggtg aagaaacggt ggcggccaca aatcgtcgag aaaaagggct
     3841 tgatgatcag ccccttgtta aagaattaca cgaaatggat aatgtcattc ttactcctca
     3901 cattgccttc tttactaatt tagcggtcaa aaatatggtg gatatttcac ttgatgatgt
     3961 gatgacaatc cttaatggcg aaaaatcacc acatgaaatt accttataat tagcaccctc
     4021 attgaccaaa agtatcgtct cgattacact atgggtatta aaaggaggga acggctatga
     4081 gtaaatataa agtaacagca actaagacaa caacggggat gcaaggttca gcaggtaccc
     4141 gtggttttga aattacattt gatgaaccag aaagtacaaa tacggggatg aatccagtag
     4201 aaattctcct tgcatcattt ggtgcctgtc aggcaatcac tgcccaagca ttagctaaaa
     4261 agcgtaactt tgatttacga gctttttggg taacaatcga gggtgatctt ggtcgtgaag
     4321 atgttgctga tggtaagaat gttcgtaagt ttactgagat ccgttaccaa ccacatcttc
     4381 gcagcagcga gtctgatgaa gacatcaaga agttcctcgc tgacgttgcc gcaaagtgtc
     4441 ccgtggaaaa cactctgacc tacggaacga aatttgttca agatggattt gtaaaagttg
     4501 attagttgaa agggagcgag acagaagtca ctcgtgactt cgttttcgag cccccgcaag
     4561 caacaatagg cctccaatat tcggttttac cgggcgttgg aggccattgg tgtactgcgc
     4621 catttgtttt tttatgaaag taacttcgct tatgtcacag tccctttcta aataggtaac
     4681 ctatacgaat tctgcaagaa acttaacgaa ttttgcaaaa tgtcctttaa attagatctt
     4741 tcattataat aaggtacaca tactgtctta gggggagaac taatgaaaat tcatttcaat
     4801 aaggactttt ggcgggatgg tttcttttat atatacttat tacttttgtt tctctggatt
     4861 gctccatttt cagatggttc gcttccatta gatgaggagc tactatgtat cttctttata
     4921 atttttacta tcggttccat gctcgcaatt atgtttaata aagactgaaa aaaggctcca
     4981 acagcaatgt tcggagcctt ttatgcattc cacaaattat agtattcttg atgatgattc
     5041 aaaagttcct ggtgagtacc ctgctcaatg atttttccgt cgcgcattac tactactcta
     5101 ttgacctttt tagcaattga aaggcggtgg gcaataaaaa tcattgtgcg gtcttcaata
     5161 ctaagcaaat tctcaacgat tcttttttca gtaattggat ctaagctact tgttgattca
     5221 tcgaaaatta aaacacgcgc agaagttagg agtgctcgtg caatcgtcaa gcgttgtttt
     5281 tgaccaccag ataatacggt tgcttcttca tctagttttg tttcatattt taagggcatc
     5341 tcttgaatat cgttatagat taatgccaat ttacatgcat tatcgatttc ttcaacagat
     5401 acttcacggt ctaatcccat tagcaagtta tctttgattg ttcccgaaaa taattgtggc
     5461 gattggggta agtaatgtac atattgtcta atatcgcaaa gattaatctc tgttgtttta
     5521 tgctgattaa attctatctg cccttgagta ggtaaataaa agccaactaa taactttgcc
     5581 aaggtcgatt taccagaacc gcttaaccct acaattgcca atttgtcatt acaaccaatt
     5641 tgaagattga tatcttgtaa aattggacga ctatattcat atgaatagtc aacatgttga
     5701 atgtttatcg gacctattaa atctgtttga tcctgagaat tcgtatctga cttttcggta
     5761 tcaacttgca gcacttcatt taatcgatta ttcgctactt tagcttcttg gagtttaggt
     5821 tgaagattaa taatattttg taatggactg ataaaaaagg ctaataacgc attaaaggcc
     5881 atcaatgtcc caatacttaa gcgaccctga attaccaaaa ctgctccttg aaaaagaatg
     5941 attgttacta agccgtattg aatccacatt ttaattgcat cctgaaaaga tttagtttta
     6001 acatatgtta gattctttcg taagaaatcc gcaaattgtt tttcaacatt tttataacgg
     6061 atattttcaa gttgcagcac tttcaatgtc tctacgcctt ttaaatcctc aataattgca
     6121 gaacttaatt gagcattact ctccatctgt tcctgatcaa gtttaacaaa gcgcttatta
     6181 aaggcataaa taataatgac ataaatcgga atggtactaa ttgtagttaa aaataatgac
     6241 cgatcatata aagaaagaac aattcctata atcaccatca cgccaacgtc taagaacatt
     6301 gaaataatag tgcttgataa ggcatcaata atcttattaa tgtcattaaa ccgtgaagta
     6361 atttctcccg tttttcttgt ggagaaaaat cgcatcggta gacgataaac atggtgaata
     6421 tatctaagac ttatttgtga tgtcagtttt tgatccagcc tagtcaaaag aacatctcgc
     6481 agataattaa aaagagaatt aaacacatac actactaata aactaccagc aaggatcgtt
     6541 aagccattaa tatttttcga gggaataaac cgatcaataa ttaattggag atagtatgaa
     6601 ccgacgatgc tgatgaaagt aattagcatt gccgcaataa caattccgga tatatctttt
     6661 ttataattag ttaattgttg aaacatcgtc gttaatccag ctaaaggttc tttttgcggt
     6721 gtatacccct tagcaggcga aaaaagcaaa catacgcctg accataaacg atcaaattca
     6781 tcccgcgtca ttttttgtac tttcgtagca ggatctggat cagctacata gatgtaatct
     6841 tgattagcct taaaaacgac acagtaatga agtaaatcat ccttaatcac atgtgcgatc
     6901 aacgggtaag taatttcagg atcatcaaac aatgatatat ctgcttgaat gggtataacg
     6961 tctaatccaa gatgctttgc tgcttttaca agtcctaagg cggtagttcc ttgcttagtc
     7021 gtccgggcta ggtcacgtaa ttttgcgatt gggtaaacag agccaaaatt gcgcaaaatc
     7081 atcgctaagg aggcaacccc acaatctgct tcatcaactt gggctacata atgaggataa
     7141 ttgattttca ttcaccttac tttctaatta gacaaagaaa taaagtccaa aattaataat
     7201 gattctgggc tttatattct tataaaatac tatttatttt ttaaataaaa ttcgtagagc
     7261 tgcaaaaata ccaatgattg tgcaagctat acatataatt gtttcataaa tgttacttgc
     7321 cttgggaatt gctaaaaccc agaagaatgt aactataata tagatataaa aatcaagatt
     7381 ggtgtaaaaa tcgcggttaa atttcataat cattaagtta taaactatta gtgaaatgga
     7441 ctatctttat agcctgcgta gcaagattga gcccatttgt tcaaggaatt aacaacatct
     7501 ctaactagtt cattaacctg tgaagagaga ctccatcctc cagaaacctt gcttaattca
     7561 tcaaagttta atttacgata agtcatttta attacctcct gatacgataa agttaggatt
     7621 ccaacattag tatataagta aaaattttct ctgtgtcatt ttgcaaaatt cgtaagcctt
     7681 tctgcagaat tcgtagtaaa attcttgaaa acgtttacta aaattgtttg acaataaaaa
     7741 aagaaaccac gacagctttt tgtcacagtt tctttgaaaa taaagtagtt agtggttttc
     7801 cttttcgaga aaatcgacta atgattttat ttttcgataa ctaacagtta ctttaatttc
     7861 tcgattcgca tcaaagtaaa ctatacgttc tttacgatta aattcttgga ttgctttagg
     7921 attaataaga gtactctgat taactttcaa taagtgttta ctatcaactt gatttagctc
     7981 accatgatac tcaattcgaa tatcctttcc aacgatccgt aaccgtcgat ttgtattttt
     8041 tactgattca atatagtaaa gcttttccaa atcaacttgt cgtttcacac cacgaatagg
     8101 ttcataggta attttttcgt ggtgtttttg attactactt acataattct gatagcgagc
     8161 atatgcttca tcaatatcaa tccggagacg atccgcaatt gactcaatct gcttaccctt
     8221 tgatatataa tcaaatggct caattcggcg cgaaacagtg taaggtaaat attcttgata
     8281 tgcagttaca aagataattt cggcaaattc agctcttttg cggatttgct ccgcaacatc
     8341 aatcccacta agttgattat ctagttcaat atctaaaatc gctaaataag cctcatcttt
     8401 gatactatca atcacttctt gcggatcatt tgtccgcaaa tataattcta tgtcataact
     8461 atttggagta gcgttaatca attttcgctg agaaactagg cgctctgtat aatcagcttg
     8521 ataatcatca ttttccaaaa taattacttt tagcatttta ttctcacttt ccctgaataa
     8581 aacaagtcat cataattacc ttatctttaa cttccgctga aaaagaataa tggtcatcat
     8641 tttctaccaa ctgtgtcaca tttgaaaggc caattccttg atgcccttct ttagtcgaat
     8701 gttcaaattt taacgcagta ttaatattaa gtttttgctc aatcgaatta gcaattacca
     8761 attcataaac ttccgggctg tgcttaagca acgcaaactg gatataaggt ttagtttgct
     8821 taaaagttgc ttcaattgca ttatccatta aaataccgat aattctagca gtttttattt
     8881 ctgaacccgg caactcgtcg atctcagcat taacttcaaa tgaaaatgga ataccttttt
     8941 ctactatttt ataagccttt tccttaataa gattatgcaa ccctgaaatt ttaatcttat
     9001 ctaatgcatt atcaatttca ccataatgct tctcaactgt atcattttga agaaacgttg
     9061 ctagcaattt ttctgcttcc ttatctttgt gatcacgaat atatccttga acactgagaa
     9121 gcatattacg tgtatcgtga cgttcacgcc gaatttcatt gtattgttgg ttcaactgat
     9181 tggcactggc aatttgcgct tgatatttat cgatgatttg ttgctgtcgt tgtgtttgct
     9241 gactactttt aacgaaatta ataaatccgg ttgcacacac tacgataatt atcaaataca
     9301 ttattaacaa cagcgaggca tacttatttg ctaccccgtc cttttcggca atagcagtta
     9361 accacacata aagcatgaac aaaattgccg taatttgcca taaccctatc ggtcgaggaa
     9421 aattaatcct aatccatctc agtttgggac gaactacttt aactgctaag attgcaacta
     9481 caatagttat gattaaatca ttaattggaa taagccatcc taaaagtgct atatctgtct
     9541 ttccttgtaa aaaaaacgta taagtatagt gatctactaa atcgaataaa gatgccatta
     9601 caatactaat acacatcgca agaatactat ttataactat ataagaatta gattttattc
     9661 tgtcaactaa ccaaaaataa aatactataa gtactgggta tagcgatcct aacataaaaa
     9721 atactattga aaaaaatata atcatcaaga ctgctaaaaa atcaattatt actaatccta
     9781 atgaaaagtc gctagttacc aattgatata ttaatattat ttcaataata tttaatatag
     9841 atgacgttaa tccttgtcct acagttaaat gaatcatctt ttaatccaat ttaaaactgc
     9901 tctttcccat gaacgaggac ttttaaaggc aagtgaatat ccccaaccac ctaatacttt
     9961 agataattct ttccttgata aaaatttata tgattttttt aacataatta cctccaataa
    10021 ataacaatta cctatttaac tacaaattca gcaatattag ccaaaactaa cattcccaaa
    10081 aacactaaaa aattcagtgg ccctgcatgc aaaatacaat acaaggcaat caatccgata
    10141 taaaaaaggt taatgattac caaatttttc ttcgtttcta aatccaaatc caccatataa
    10201 ctaactccta ctttatccat ccctctgata atgcaaaaga aataataatt gttaaaacaa
    10261 agcaagctat tgcaatcata attgcgcgtt cagcactcgg gcgcacaaca tctcctcctt
    10321 tagtagataa ccacaggctc atttttatgt aagtcactaa aagcttgacc agctacatct
    10381 ggatgcatgt taatacaacc gtgcgatcca ccgcctttag caagataagc ctgttttgac
    10441 caatcgtgac gccaacttgc atcatgaaat ccacatccac tatcagtaaa tggtgaccaa
    10501 tattgaactt tgctagcgta tttcgaaccg tcatcgttaa ggccccgaag aacagacggt
    10561 gtttgctggt acatgatata ccagacaccc ttcggcgtct cgttatcttt gttattggtc
    10621 ccactaacaa tgtcagtgct aagaacacat ttaccattct tatagaacca cgcatgttgg
    10681 tcggctaatg aaacttcggc gtaagtgtcc cctatgccgt tgttacttgt ggtattatac
    10741 ccagttcctt gttgattata acccttacca taaatatcat tttttgcatt tactgtttgc
    10801 ttattttcaa tcaatgcatt cgtaagagtc tttccagctt gtttcttact gatcttccaa
    10861 ccatatgaac cagcagccgt tgttttaatc actgatccac tgtgagtttt gaactcaaat
    10921 ggctttccca aagtagcttg ctgattattg atttcatcaa tttttgtacc taatactttg
    10981 gtattaaaat gatacttgcc atcttgataa gtagctcgag taatgatatc cgcactggtc
    11041 aaatggtact tcttaccttg gacttgatag gtcacgtccc gcttagctat ctgttctagc
    11101 ttcgtttttt cattttgtac tgtcttactc ttggcagaaa gcggagcctt gtaaattggc
    11161 tttagtttaa cctctccctg cacaagttct ttttcgactt gattatgcaa accatctaaa
    11221 ctgtactgag taccgccaac tgctggtcta acctgtactt gaccattttc gtataccgca
    11281 taagcattaa ttggtgcttt gcgcccatta tttagttcca ttaccttttg actaacggcc
    11341 tgatcaacct gtggaacaac actttgatta aacttttgtg gcttaatcag caaattttta
    11401 tccttattag atggaaaaaa ggtatattga cgatgcaagg cgttagccac cttttcttca
    11461 tcagcttggg taaatttagc aactggttgt tttcctgtat aaactaggtc gttgttcacg
    11521 tatactttgg gtgtttgcgg gttatcttgc aattttttta gtgcttgctt agccgttaaa
    11581 ccaccgaccg ctacattatc aattttgaca tttttattaa agtgccggcg ctgatgaatc
    11641 gtcatcaaac ccattaccag tactagcaaa cctaatgtga ttattatcag ttgtttaata
    11701 gataattttt gcataaaagt actccaactt aataagttaa ataatagaaa tgccctacac
    11761 gctaataatt atagcagtag ggttttctat attaaacaaa aaaataatat ttttattaca
    11821 aaacacgacg agcaaagttt ggcatccagt aactcattgg ttgttctttt actgtttgac
    11881 caggttgtgg tgcaaataaa gtcttaccat ttccagtgta aattccaaca tggtatgcac
    11941 ttcctggatt accccagaat aagagatccc ctagttgtaa gttattcatg ctgacgctgt
    12001 acccttggtt agattgttgg gcagctgtcc gtggtaagtt aactcctgcc tgacgataaa
    12061 cgtattgaac caatccagag caatcaaatg aattaggacc cgttgccccg tatacatatg
    12121 gctttccaag ctgctgacga gctaaggaaa t
//
