LOCUS       c00021_gnlPro..        22753 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GDABHCCE_51.
ACCESSION   c00021_gnlPro..
VERSION     c00021_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 09:35:23
            Original ID  :: gnl|Prokka|GDABHCCE_51
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 8353
            Orig. end    :: 31106
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22753
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[18353:24873]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..16520
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..22753
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22753
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(470..1924)
                     /locus_tag="ctg21_9"
                     /transl_table=11
                     /translation="VPTEIKGLNEECGVFGVFDAANASQLTYYGLHTLQHRGQEGAGIV
                     STDGTELYQHRDRGLLAKVFADPAELKRLKGNAAIGHVRYGTSGHNSIANVQPFLFHFH
                     DGAVALAHNGNLTNAVTLRRELENEGAVFQSDSDTEILIHLIRKYINEGFIPALKKSLN
                     LVHGGFAYLLLQKDRLIAALDPNGIRPLCIGRLENGAYVVTSETCALDIINAQFVRDVL
                     PGELIIIDKNGLHIDHYTTQTQLAICSMEYIYFARPDSIIHGVTVHNARKRMGKFLAKE
                     HLVDADMVIGVPNSSLSAASGYAEESGLPYEMGLIKSQYVARTFIQPTQELRELGVQMK
                     LSAVRGVVKGKRVVVVDDSIVRGTTSKQIVQMLKRAGAKEVHMLISSPPFKFPCFYGID
                     VSTRSELMAAHYSIEEMRQLIGADSLNFLSIDSLIQAINVPDAGDAPNGGLTVAYFDGK
                     YPTPLYDYEEGYLKSLSEQERLARKG"
     CDS             complement(1900..4128)
                     /locus_tag="ctg21_10"
                     /transl_table=11
                     /translation="MKQAMTPEEIKEKKPYLDWSLTEAEYDYIRTQLLGRLPNYTETGL
                     FSAMWSEHCSYKKSKPVLRLFPNKNERVLQGPGEGAGVVDIDDGQAVVFKAESHNHPTT
                     VEPYQGAATGVGGILRDIFSMGARPIASLDSLHFGELDNSTTRMKVTNTVRGIGDYGNC
                     MGIPTIAGETTFDPCYQGNILCNAMSVGLMDQKDIQQGRAAGIGNAVMYVGAKTGRDGI
                     HGATFASADFNDENMTQRSAVQVGNPFMEKLLLEACLDLIRNHPDWLVGIQDMGAAGIV
                     SSSAEMASEGQSGMELNLDLVPQREPGMSAYEIMLSESQERMLLCVKKGHEEDVKKIFD
                     FYDLEAVTIGRITAGHDYVLFHDGEEVCHIPVSSLTDDVLEEESLEKKPARIELAEQQP
                     TWIPDIDNVAEVLTALLAQSTIADKSSLYQQYDSQVRTNTVAGPGSDAGVLRIRGTHKG
                     LAMTTDGNGRFVYLSPEVGGQIALVEAAANIIASGAEPLAITDCLNYGDPTDPEIFWEL
                     HQSVQGMADACREFNTPVISGNVSLYNENNGQAIHPTPMVGMVGLIKNIDRVIPSFVQH
                     PGDKVYLVGQTRDDYAGSELQKMMTGDISGIVKSFDLHHVHQYMQRLLTTMENGLVSSA
                     HDLSEGGLGVALAETVFKTDLGLKVDFADQPATRLFSETPGRFIVTVAPEKATEFEQAL
                     GKDAHLIGEVTNSHWLMVKLANGELNESVAKLQKTWEEAIPCQLKSKD"
     CDS             complement(4132..4812)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_11"
                     /sec_met_domain="GATase (E-value: 3.2e-09, bitscore: 27.6,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAVVVFPGSNCDVDLYEALHSVCHADVEYVSHRQKSLAGFDAV
                     MLPGGFSYGDYLRAGAIARFTNIMPAIIKMANEGKPVFGTCNGFQILTEAGLLPGGLKR
                     NDSQRFVCKTVPLEVVNSQTLFTSHYQDHERIALPIAHADGSYYADEKTLDELEANNQI
                     VFRYATENPNGSLRNIAGITNKHGNVLGMMPHPERAVETILGSTDGLRLFESLLENGRI
                     KVEA"
     CDS             complement(4813..5061)
                     /locus_tag="ctg21_12"
                     /transl_table=11
                     /translation="MVNVRIFVTYKQSVFDPQGETIKDAIHSLGHDEVTAVKVGKFFDV
                     TLDTNEDEVATAVKEIADQLLVNFNMETYTYQVMEEA"
     CDS             complement(5062..5781)
                     /locus_tag="ctg21_13"
                     /transl_table=11
                     /translation="MEKLLYTGKAKQMWQTEDPAVLRVVYLDQATALNGKKKDHFTGKG
                     KAANAISSLVFDYLMKQGIETHFIKKLSTNEDLVKKCEMFPLEFVTRNVIAGHFASRYG
                     LSEGEELPSPVEETFYKSDELNDPFINESATIALEIASKEELAQMWGICRKVNNLLKPL
                     FAKANLRLVDFKLEFGRLSDGKIILADEFSPDNCRLWDLTTKQHMDKDVYRRKLADLTQ
                     TYDEVLERLEAVIKEEA"
     CDS             complement(6006..7301)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_14"
                     /sec_met_domain="Lyase_1 (E-value: 1.8e-63, bitscore:
                     205.5, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDRYTSPEMKKIWSLETQYQCWLDVEIAADEAWSKLGHIPAEDV
                     EKIKKNAKFSVEGIAEIEAVTHHDVIAFTRDVSKSLGPERKWVHYGMTSTDVVDTAQGL
                     RLKKANDILRQDIDNFMDILKELAEKYKYTVCMGRTHGIHAEPTTFGLKAARWYSEMKR
                     NKERFEHAAKGVEAGKISGAVGTFAEIDPFVEEYVCKKLGLRPQEISTQVLPRDLHAEY
                     IATIALIGTSMEEMATEIRSLQRTEIHEVEEHFAKGQKGSSAMPHKRNPIGSENITGCA
                     RMLRGFMVPAYEDVSLWHERDISHSSAERMILPDATSLLDYMLRRFGRLLKNLDVFPET
                     MKKNMDETLGLIYSGRVLLKLVNSGMTREAAYDLIQPYTAKCWAEQIPFRPLLEDDPTI
                     QKQLTKEDLDDAFDYHWHLRHVDDIYKRLGLD"
     CDS             complement(7373..8527)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hacid_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_15"
                     /sec_met_domain="Hacid_dh_C (E-value: 1e-09, bitscore:
                     28.7, seeds: 144, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 2.7e-12,
                     bitscore: 37.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKQKKVGSILNKFIPQGSTIGIIGGGQLGQMMALDAKQTGMKVI
                     ILDPTPHCPAGQVADEQIVAPYADTKAIEKLADKADVLTYEFENVDLSALEDVQDRVYL
                     PQGTNLLYTTKNRLREKNFLRQAGVKTAPFMAVHTLAELKDAVKKIGYPAVLKTSEGGY
                     DGHGQEVLRNKDDLDKCAPILATSDCILEGWVPFNRECSVMVGRNEDGEITAFPVSENI
                     HHDEILHLSIVPARISSELQQKAQKIAVQIAQAINLRGILGVEMFVTDDGEIYINELAP
                     RPHNSGHYSIEACNFSQFAIHNRAICNWPLPQVELLKPVVMVNVLGQHVNGVRQQIQKK
                     ADWHFHDYGKAEVRHNRKMGHVTILTDDIEATLAEIDNTGIWSA"
     CDS             complement(8490..8975)
                     /locus_tag="ctg21_16"
                     /transl_table=11
                     /translation="MSDISVVMGSKSDWPTVKETCDILDEFGVSYEKNVISAHRMPNEM
                     FAFAQNAVDNGVKVIIACAGGAAHLPGMIAANTPLPVIGIPGQTKALGGMDSLLSIVQM
                     PAGIPVATTAIGKAGAKNAALLALQILGITDKHIQQQIIEYRQAMHDQAKESGQYLE"
     CDS             complement(9129..9989)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_17"
                     /sec_met_domain="GHMP_kinases_C (E-value: 3.3e-10,
                     bitscore: 31.1, seeds: 112, tool: rule-based-clusters)"
                     /sec_met_domain="GHMP_kinases_N (E-value: 5.1e-15,
                     bitscore: 46.4, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIQAPASSANLGPGFDSIGIAVSLYLKLEVLGPSDNWQVDHQLG
                     KLPHDETNMIVTTALSVAPDLLPQHLRVVSEIPIAHGLGSSSSAIVAGIELANQLKNLN
                     LSKEEKVEIASQIEGHPDNVAPTILGGLVVGTHINGHFSAIEAPLFPYAFAAYIPPYNL
                     KTADARAALPYQLEYSQAVHASAVANTFVASLFAKNYDVAFKLMEADRFHEPYRKELVP
                     ELDQIRELGKKHGALATYLSGAGPTVMTVIDNDDYGLFEQAVHAAGLKGKVVRLHPDVE
                     GVKLI"
     CDS             complement(10001..11275)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: Homoserine_dh"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_18"
                     /sec_met_domain="Homoserine_dh (E-value: 2.7e-65, bitscore:
                     210.3, seeds: 932, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNIKLGLLGLGTVGSGVLQMVQQNADKIIDVTGCKLTVKTALVR
                     NLGNYNKYADETSLTTDFDEILNDDEIKIVVELMGGIHPAKEYITTLLKNHKNVVTANK
                     DLIASYGPELMTVAHENHCDLMFEASVAGGIPILRTIANSFTADKVTEVKGIVNGTTNY
                     ILTQMSQRGWSYHQALAQAQQLGFAESDPTNDVTGKDAAYKMIILSQFAFGTQLDIKDI
                     AVEGIDRLNDADVQQAASFGYVIKLLGITKLVNNGVFVEVGPVLIPRDHPLATINNEFN
                     AVMVTAQAVGDTLFYGRGAGGLPTANSVLSDITTVTKNIILGTNGNLFNNYQQPYIPAK
                     LADIKYPYYLSLTLPDVPGQMLKLTQMMTNINASFREITQTKDGKIAHIAIITHRMSKE
                     QLQTLLTKVANDQSINLSAAYKVMG"
     CDS             11382..12875
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_19"
                     /sec_met_domain="PALP (E-value: 2.6e-14, bitscore: 44.0,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYRSTQGDLSTILKSPTAILQGLSPDGGLYVPLHFPQPTYNLAT
                     LISLPYQQLAATILNWFFDEFTSDQLLKNANTAYGSQWDNRLIAPLTPKHASNYYLELF
                     HGPTLAFKDIALQMLPQLVSRAAQNTQLEKQIVILTATSGDTGTASMRGFSNQKDTQVI
                     VFYPAGGVSPVQLRQMLGQPGSNLHAIAIKGNFDDAQTSVKHIFNDQAFNDRLAQNNNC
                     FSSANSMNIGRLIPQIVYYFAAYGQLVHTGGIQLGEKVNFTVPTGNFGDILAGYYAKKL
                     GLPINKLLCASNENNVLTDFFKSGKYERRRNFYLTNSPAMDILVSSNLERLLFDLYDES
                     CVTVAKLMKQLATDGHYQVDSTVLNKLQEQFVAGFATPDEVEAEIKRVYLNDGYVIDPH
                     TAVASHVTHQYQQQSHDTTPTVIVSTASPYKFPETVYHALTNQKVSQSGLPALQQLHDL
                     LGDQLSAGVQALVDQTPRQEKVINPADMETLISKILNLK"
     CDS             complement(14108..14824)
                     /locus_tag="ctg21_20"
                     /transl_table=11
                     /translation="MTTLYEHGTLAALMAGNFDGTITVSDLLKHGSMGIGTFTGLDGEV
                     VILNNEVYQAVSSGQVNRITDMDATMPFASVHFPAEQQDITLRNVNFAKLNNDFVKEHQ
                     LANVFAFLQLSGEFKHVKIRIAPKQEKPYPTLLDVAQHQPEFTAENISGTIIGYYAPDI
                     FGTITAAGWHLHFISDDRQFAGHLLAFDASKLTGSFEVFDNLEQHLPIDNKEFRASEVD
                     MATLRDGIAKSEGNAD"
     CDS             complement(14841..16520)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_21"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2e-44, bitscore:
                     141.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKKLHGADIVIDSLRKHGVNLVFGIPGAKIDRLFEGLDGQDSED
                     APKLIVTRHEQNAAFMAQAYGRLTGKTGVAITTSGPGVGNLVTGIMTANAEGDPMLAIG
                     GQVQRKDLHRATHQSTPSTEIMAPITQYSAEIQDPNNISEIMANAFEASQDARKGAAFV
                     SLPQDVDDAEVTEKPLPIYETPKMGPADPNDLQKLVELIKNSKMPVILVGQRGADEKIT
                     TALRKLLSDYSLPVVETYQAAGVVSRDLEQQSYFGRIGLFRNQVGDQLLQQSDLVITVG
                     YDPIEYEPQNWNKEGNLRIVNLDTLPAQIDNHFTPIMQLVGNIATSLTELDKLLKGYEY
                     PVAATEQLAKYKQELDQDKKIQIPASDDASHPLAVVHAIQENVTDDMHVALDVGSHYIW
                     MARHFRCYQPRHLLISNGMQTLGVGLPWAMVAAMLYPEHKSVAVCGDGGFLFSGAELAT
                     AVQYHLNVVTIVWNDGGYYDMVKFQEEMKYPQAAGVKFGNVDIVKYAESFGATGLRVNE
                     PADLTKVISQAFNIDGPVVVDVPVDYSNNKELAANLIDSQLG"
     CDS             complement(16715..18376)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_22"
                     /sec_met_domain="FTHFS (E-value: 1.6e-261, bitscore: 859.0,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDIEIADQATLEPITEIAEKLGLSEDEIEQYGKYKAKIDLNVKP
                     LPDKKHKLILVTSINPTPAGEGKSTVLIGLGDALNQLNYQTTIAMREPSMGPVFGIKGG
                     ATGGGYSQVVPMEDINLNFTGDLHALTSANNTLAALIDNYIMRDNAMNLDPRRIIWKRV
                     EDVNDRALRNVVTGLGGPMAGVPRETGFDITAASELMAILCLSTSLHDLKERISRIVVG
                     YTYDKEPVTVGQLNFQDAITIILKDALKPNLVQTLDHTPTIVHGGPFANIAHGCNSVLA
                     TQTALNLSDYTVTEAGFGADLGGEKFLDIKQRVLGKHPDAIVIVATVRALEYNGGAKLA
                     DLNEENLDALKKGMANLNRHIKNMQLYGLPIVVAINHFVSDTDKEIQMIKDDCAKQNVE
                     AILTDAWAKGGKGTHDLANKVVELADSPSEFTHIYDVQVDDLQTKLEKIAKQIYGAKEV
                     SFSRKAQNQLKRFAKYGWNDLPVCIAKTQYSFTDDQKQLGAPTDFTFHIRELVPKIGAG
                     FVVALAGNMMTMPGLPKEPAAVNMTIDDNGKITGLF"
     CDS             complement(18546..19580)
                     /locus_tag="ctg21_23"
                     /transl_table=11
                     /translation="MTNAWKHFIENVKLRRFTVLLLIIVVLWLMRSMMNLILFTFILTY
                     LVVSWVRLVQRWLPRMSTSLIVIVTYVLLIVLLYLGVTRYLPVLSRQVVKMVNSVVHFY
                     STHQATMIYRYVSHYVSTATIMSQVRHGITIAVSTLTSIGAITVSFVMSLILSFFYTLE
                     LKQMNEFSHSFLDSDFGWFFQDIDYFGKKFVNTFGVVLEAQFFIAICNTVITMIGLLFM
                     RMPQIFALSLIVFIFSLVPVAGVIISTIPLAMVGYSVGGIRDVVYIIIMIIIIHTLEAY
                     VLNPKFMSSRTDLPIFYTFIVLLIGEHLFGTWGLIVGVPIFTFLLDVLGVKPIRGAKKE
                     VSKK"
     CDS             19751..20926
                     /locus_tag="ctg21_24"
                     /transl_table=11
                     /translation="MLEKTFYKSLLKHSFNIPVKIVFWDGSSVIYGDGTPEVTITFKEK
                     IPMRDITKNASIALGEAYMDKKIEIQGSIQELIESAYESADSFMRSSKFRKFLPKQGHS
                     EKESENDVQSHYDVGNDFYKLWLDDTLTYSCAYFTDGNHDDLTKAQVDKVHHILKKLDP
                     KPGKTLLDIGCGWGTLMLTAAKEYGLKVTGVTLSEEQYRLVKERIEKEGLQDVAEVKLV
                     DYRELGDQKWDYITSVGMFEHVGKENLGLYFKDIQGYLTDDGVALIHGITRQQGGAYNG
                     WINKYIFPGGYVPGLEEMIGHIEENHMQIADIEMLRRHYQRTLEIWDMNFNEHRAQILD
                     MMGERFTRMWDLYLQACAASFESGNIDVIQYLITKGPSGKNLPMTRDYMTK"
     CDS             21183..21845
                     /locus_tag="ctg21_25"
                     /transl_table=11
                     /translation="MQSQFSTVEEALNQLVNGGYIILADNEDRENEGDLVALGENVNAD
                     TIYEMLNEANGLMCVPVSEGIAKHLAFKPMVEHSTDPHQTPFMVTTDGTLEATGVTTGV
                     SAFDRAATIRQIAKPTAQASDFNHPGHIQPLYAQPHGLRDRIGHTEAAIDLAYLAGKAP
                     VAVIIEVLKRDGTMARRDSLSVLANRVHVPFITINQIIEYLDVKGIDYAADLAKVNA"
     CDS             21922..22563
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg21_26"
                     /sec_met_domain="HAD_2 (E-value: 2e-14, bitscore: 44.8,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDGAIFSFNNIFVNTNKLSFTAWQRFAMYEFGMGLPGKLASQFDN
                     LTPSQGLSLVLAHFNANPAPSEKASMIAEWQKFLNEEADSLSEKDQLPGIKRLLLNLYD
                     HYVKIAVLDTNGDVQNVLKQIGLDNYVDSIVKTNDKENPYLTAVNQLNLIGANCIGVGT
                     TAHDIENIHHINAIAIGVGDAKTLASADYQVVQVGDLRYPMLQKIWEDKQ"
ORIGIN
        1 tgttcctgcc aggtcatact cattggctgc atacatatct ggcatttctg ctgtttctcc
       61 accaattaaa gcggccccag cttctcggca accagtcgct actccgctaa caatcgctgt
      121 catcttagcc ggatcattat ggccggtcgc aatgtagtcg agaaatgtta ttggttccgc
      181 tccctgcgcc aggacatcat taacacacat tgcgacaaca tcgatcccga ttgtatcgtg
      241 cttattcatt tgttgggcaa ttaagagttt cgttcccaca ccatcagtgc cagagacaag
      301 aatcggatgc cgtacctgta atttttctaa gtcaaacatc cccccaaagc tgccaattcc
      361 cccaatcaca cctgggcgat cagttgattt gactgcatct ttaatacggt gaacaagttc
      421 gtacccggca tttacatcta cccctgcatc ttgataacga ctcatcctct tacccctttc
      481 ttgctaatcg ctcttgttcg cttaacgact ttaagtaccc ttcttcataa tcataaagcg
      541 gcgttgggta cttcccatca aaataagcca cggtaagtcc accattagga gcatctcctg
      601 catctggtac gttaattgct tggattaaac tatcaatact caaaaaatta agagaatctg
      661 caccaattaa ctgccgcatt tcttcaatgg agtaatgagc agccatcagt tctgaacgcg
      721 ttgatacgtc aatcccatag aaacatggaa acttaaatgg tggtgaggag ataagcatat
      781 gaacttcttt ggccccagct ctttttagca tttggacaat ctgcttagaa gttgttccgc
      841 gcacaatcga atcgtcgact actaccactc tttttccttt tacaactccg cggacagctg
      901 ataatttcat ctgaacgcct aactcccgta actcttgagt tggttgaata aacgtccgcg
      961 caacgtattg gctctttatt aaccccattt catatggaag gccactttct tcagcatacc
     1021 cactagcagc agataacgat gaattaggta ctccaatcac catatcagca tcaaccagat
     1081 gttcctttgc taagaacttt cccatgcgtt tacgtgcatt atgtaccgtt accccatgaa
     1141 taatagaatc aggacgggcg aaatagatat actccattga gcaaatcgcc agttgagttt
     1201 gggtagtgta atgatcaata tgtaacccat ttttatcaat aattattaat tctcctggca
     1261 aaacatcacg cacaaattga gcattaataa tgtctaaagc acacgtctca ctagtaacaa
     1321 cataagcgcc attttctaac cttccaatac ataaaggacg aatcccatta ggatctaaag
     1381 ccgcaattag ccgatctttt tgcagtaata gataggcaaa tccaccatgg acaaggttga
     1441 ggcttttctt caaagcagga ataaaacctt cattaatata tttccggata aggtgaatta
     1501 aaatttccgt atcagaatct gactggaaaa ctgccccttc attttccaat tcacgacgaa
     1561 gggtaacagc attagttaaa ttaccattgt gggcgagggc aacagcacca tcatgaaagt
     1621 gaaaaaggaa gggttgaaca ttagcaatcg aattatgtcc acttgtccca taacgaacat
     1681 ggccaatcgc agcgtttcct tttaatcgtt taagctcagc cggatcagca aacactttcg
     1741 ccaacaatcc tcggtcacgg tgctgataaa gttccgtccc atcagttgag acaatgccgg
     1801 ctccttcttg gccgcgatgc tgaagagtat gcaggccgta ataggttaat tgactagcgt
     1861 tagccgcatc aaaaacccca aagaccccac attcttcatt taatcctttg atttcagttg
     1921 gcacggaatt gcctcctccc atgttttttg taattttgca acactttcat tgagttcacc
     1981 atttgccagt ttaaccatta accagtggct atttgtaact tctccaatta ggtgtgcatc
     2041 ttttcctaat gcctgttcga attcggttgc cttttcagga gcaaccgtca cgataaatct
     2101 tccaggagtc tcactaaaca ggcgagttgc tggctgatca gcaaagtcaa ctttcaaccc
     2161 taaatcagtt ttgaagaccg tttcggctaa agctactccg aggccacctt cactcaaatc
     2221 atgggcactg gaaacaaggc cgttctccat cgtcgtcagt aaccgttgca tatattgatg
     2281 aacatggtga agatcaaatg acttaacaat tccgctaata tcgccggtca tcattttttg
     2341 caactcagac cccgcataat catcacgagt ttggcccact agataaacct tatctcccgg
     2401 gtgttggaca aacgaaggaa ttacgcgatc aatattttta attagaccaa ccattccaac
     2461 catcggcgtc ggatgaattg cttgcccatt gttttcgtta tataaagaaa cattcccaga
     2521 aataaccggg gtattaaatt cacggcaagc atcagccatc ccttggacag attgatgaag
     2581 ttcccagaaa atttctggat cagttgggtc accataattt aagcagtcag taattgctaa
     2641 cggttcagct ccactggcaa ttatgttggc agccgcttca actaaggcaa tttgtccacc
     2701 aacttctgga ctaaggtaaa caaaccgacc gttcccatca gttgtcatcg ctaacccttt
     2761 atgtgttcca cgaatccgca gaaccccagc atcactcccg ggaccagcca ctgtgtttgt
     2821 ccgtacttga gaatcatatt gctgataaag actactttta tccgcaatcg ttgactgagc
     2881 aagcaaggca gttaaaactt cagcaacgtt atcaatatct ggaatccacg ttggttgctg
     2941 ttcggctaat tcaattcgcg caggcttttt ttcgaggctt tcttcttcta gtacgtcatc
     3001 cgttaaactc gacactggga tatgacatac ttcttcacca tcatgaaaga gaacataatc
     3061 atgacccgca gtaatccggc caattgtgac cgcttcaaga tcgtaaaaat caaaaatctt
     3121 tttgacatct tcttcatggc ctttttttac gcaaagaagc attcgttctt gggattcact
     3181 aagcataatt tcataagccg acatcccggg ttcacgttgc ggaacaagat ccaaatttag
     3241 ctccattcca ctttgacctt cggaagccat ttccgcactt gaagaaacaa ttcccgctgc
     3301 ccccatatct tgaattccta ctaaccagtc tggatgattt ctaataaggt caagacaggc
     3361 ttctaataag agtttttcca taaaaggatt accaacttga accgccgaac gttgcgtcat
     3421 attttcatca ttaaagtctg cggaagcaaa ggtggcgcca tgaattccat cacggccggt
     3481 tttagcgccg acatacatca ctgcatttcc aattccggca gcgcgaccct gctggatatc
     3541 tttttggtcc attaagccaa cactcattgc attacacaga atattgccct ggtagcatgg
     3601 atcaaatgtt gtttcacccg caattgtagg aattcccata caattaccgt aatcaccaat
     3661 tccccgaaca gtattagtta ctttcatccg cgttgtcgaa ttatctaatt caccgaaatg
     3721 gagggaatca agggaagcga ttggtcgtgc acccatgctg aaaatatctc gcaggatccc
     3781 accgacacca gttgccgctc cttgataagg ttcaacagtt gtcggatgat tgtgactttc
     3841 agctttgaat accactgctt gtccatcatc aatatcaaca acccctgctc cttctccggg
     3901 accttgcaat actcgctcat ttttattagg gaagagacgc agaaccggtt ttgacttttt
     3961 atatgaacag tgctcactcc acatcgcaga aaacaagcca gtttcagtat aatttggtaa
     4021 tcgtcctaag agctgggtac gaatgtaatc atattctgct tcagtcaagc tccaatctaa
     4081 gtatggtttc ttttctttaa tctcttctgg ggtcattgct tgtttcatta actatgcctc
     4141 cactttaatt ctgccgtttt ctaacaagga ttcaaataac cgtaagccat ccgtactacc
     4201 aagaatagtt tctactgccc gttcaggatg gggcatcatg cctaagacat ttccgtgctt
     4261 attagtaatt ccagcaatgt tgcgtaaact accatttgga ttttcagtcg cgtaacgaaa
     4321 aacaatttga ttatttgctt ccagttcatc tagtgttttt tcatctgcat agtaactacc
     4381 atcggcatgc gcaattggta atgcgattcg ttcgtgatcc tggtaatgac tagtaaaaag
     4441 agtttgcgag ttcactactt ctaaaggaac agttttacaa acaaagcgtt ggctatcatt
     4501 gcgtttgagt ccacctggca aaagacctgc ttctgtcaaa atttgaaatc cgttacacgt
     4561 tccaaagact ggtttcccct catttgccat tttgattatt gcaggcatga tattggtaaa
     4621 ccgagcaatt gcgccagctc gtagataatc accataggaa aatcctcctg gtaacatcac
     4681 agcatcaaaa ccagctaaac ttttttgccg gtgagagaca tactccacat ctgcatggca
     4741 aacggaatga agggcttcat ataaatccac atcgcaattg gatcccggaa aaacaaccac
     4801 cgcaattttc atctaggctt cctccataac ttggtatgta taagtttcca tattgaaatt
     4861 aacaaggagc tgatcggcaa tttcttttac tgccgttgct acctcatcct catttgtgtc
     4921 taaggtaacg tcaaagaatt tcccaacttt aacggcagtt acttcatcat gacctagaga
     4981 atggatcgca tccttaattg tttctccctg cggatcaaag actgattgct tatatgttac
     5041 gaaaatccga acattgacca tttatgcttc ctccttaatc actgcttcta accgttccaa
     5101 tacctcatca tatgtttggg ttaaatcagc aagtttgcgt cgatatacgt ctttatccat
     5161 atgttgctta gttgtcagat cccataaccg acagttatct ggcgaaaatt catctgcaag
     5221 aataatcttg ccatcactta aacggccaaa ttcgagtttg aagtcaacca accgtaaatt
     5281 agctttggca aataatggtt taagtaagtt attgaccttc cgacagatcc cccacatttg
     5341 cgcaagctcc tctttgctgg caatctcaag agcaatcgtt gcggattcat tgataaaggg
     5401 atcattaagt tcatcgcttt tatagaaggt ttcctcaact ggtgaaggaa gctcttcccc
     5461 ttctgaaagt ccataccgac tcgcaaaatg accagcaatt acattccgcg ttacaaattc
     5521 aagcgggaac atctcacatt tttttacaag gtcttcgtta gttgatagtt tcttaataaa
     5581 gtgggtctca attccctgct tcattaagta atcaaaaacg agggaagaaa tagcattggc
     5641 agccttaccc ttaccagtaa agtgatcctt cttttttccg ttgagggcgg tagcttggtc
     5701 cagataaact actcgtaaaa ccgctggatc ctcagtttgc cacatttgct ttgccttgcc
     5761 ggtatacaat aacttctcca tttacggaac ttcctttcag taaaacacga acatttattt
     5821 taatatccga aaattaattc gatatttcat gacaacaata tactctcccc ttctcccttt
     5881 tgtcaatacg aattacgata tttatatgat ttttcacctg gattgttcgt gtttttactg
     5941 gataaagcat aacaaaaagg ctagacaaac ttttttgttc gtctagcccc ttaaactagc
     6001 ttatattagt ctaatcccaa tcgtttataa atgtcatcaa catggcggag gtgccagtgg
     6061 taatcaaagg catcgtcaag atcttcttta gttaattgct tttgaattgt tggatcatct
     6121 tccaatagtg ggcggaatgg aatctgttct gcccagcact tagcggtata tggttgaatc
     6181 aaatcataag ctgcttcccg agtcattcca ctgttaacca acttcaaaag aacccgacca
     6241 ctgtaaatta agcccaatgt ctcatccata ttcttcttca ttgtttcagg gaatacatca
     6301 agattcttta agagtcgacc aaaacgccgc aacatgtaat caagtaatga agttgcatct
     6361 ggtaaaatca ttcgctctgc actggaatga gaaatatccc gttcatgcca aagcgaaaca
     6421 tcttcataag caggtaccat aaagccacga agcatccgcg cacaaccagt aatgttttct
     6481 gagccaattg gattacgctt atgtggcata gcagaagatc ctttttgtcc cttagcaaag
     6541 tgttcttcga cttcatggat ttccgttcgt tgaagagagc gaatctcggt tgccatttct
     6601 tccatacttg ttccaataag cgcaatggta gcaatatatt cagcatgtaa atctcgcgga
     6661 agaacttgtg tggagatttc ttgaggacgt aagccaagtt ttttgcagac atattcctca
     6721 acaaatgggt caatttcagc aaaagttcct actgcaccag aaattttacc agcttcaaca
     6781 cccttagcag catgttcaaa acgttcttta ttacgcttca tttctgaata ccaccgagca
     6841 gctttcaagc caaaagttgt tggttcggca tgaataccat gtgttcgtcc catacaaact
     6901 gtgtacttat atttttcagc taattcttta aggatatcca taaagttatc aatatcttga
     6961 cgaaggatat cgttcgcctt ttttaatcgc aagccttgtg cagtatcaac tacatctgta
     7021 ctcgtcattc cgtagtgaac ccactttcgt tcaggcccca atgatttaga aacgtcccgg
     7081 gtaaaagcaa tcacatcatg atgggtcact gcttcaatct ctgcaattcc ctccacagaa
     7141 aacttggcat tctttttaat cttttccaca tcttctgctg gaatatgccc tagcttactc
     7201 cacgcttcat cagcagcaat ctcaacatct aaccaacatt ggtattgtgt ttctaagctc
     7261 caaatctttt tcatctctgg actggtataa cgatcaatca tcagttaaaa atcctctcta
     7321 ttttttctaa atgtattatc gcacaggaaa agcggttacg taaagccgaa ctttatgcac
     7381 tccaaattcc tgtattgtca atttctgcta aagtagcttc aatatcatca gtcaagattg
     7441 taacgtggcc cattttccgg ttgtgacgaa cttctgcttt cccataatca tgaaaatgcc
     7501 aatctgcctt tttctgaatc tgttgtcgga ctccattaac atgctgaccc aaaacattta
     7561 ccattaccac cggctttaat agctctactt gcgggagtgg ccagttacaa attgctcgat
     7621 tatggatggc gaactgtgag aagttacaag cttcaattga ataatgacca gaattgtggg
     7681 gacggggagc aagctcatta atatagatct ctccatcatc tgttacaaac atttcaaccc
     7741 ctaaaattcc tcgcaaatta atcgcttggg caatctgcac cgctattttt tgcgcctttt
     7801 gttgtaattc agaagagatc cttgctggaa caatgcttaa atgtagaatt tcatcatggt
     7861 gaatattttc tgaaacagga aatgccgtta tttctccatc ttcattacgt ccgaccatta
     7921 ctgaacattc gcggttaaaa ggaacccatc cctctaagat acagtcgcta gtggctaaaa
     7981 taggggcaca cttatcaaga tcgtccttat tacgtaacac ttcttgccca tgtccgtcat
     8041 atcccccttc actggttttc aaaactgctg ggtaaccgat tttctttacc gcatctttta
     8101 attcagccaa agtatgcact gccatgaaag gtgctgtttt tacccctgcc tgacgtaaga
     8161 aattcttttc ccgtaaacga tttttggtcg tgtaaagcaa gttagttcct tggggaagat
     8221 aaacgcgatc ctgcacatct tccaaagcgc ttaaatcaac attttcaaat tcgtaggtta
     8281 atacatccgc tttatcagcc aacttttcaa tcgctttagt atcggcataa ggagcaacga
     8341 tttgttcatc agcaacctgc cccgctggac aatgaggggt tggatctaaa ataataacct
     8401 tcatccccgt ctgtttggca tccaatgcca tcatctgtcc caattgccca ccaccaataa
     8461 tgccaatcgt tgaaccttgt ggaataaatt tattcaagat actgcccact ttcttttgct
     8521 tgatcatgca tcgcctgtcg atattcgatg atttgttgtt ggatatgctt atctgtgatc
     8581 cccagaattt gcaatgctaa taacgcagcg tttttagctc ctgcttttcc aatcgcagta
     8641 gttgccaccg gaattcccgc tggcatttga acaattgata aaagcgagtc cattccaccg
     8701 agagctttcg tctgtcctgg gatcccaatt actggcaggg gggtattggc tgcaatcatg
     8761 cccggaagat gggctgctcc cccggcacac gcaataatta ctttaacccc attatcaacc
     8821 gcattttgcg caaacgcgaa catttcgttt ggcatccgat gagcagaaat tacattcttt
     8881 tcatatgaaa caccaaattc atctaaaata tcacaagttt ctttaacagt tggccaatct
     8941 gatttactgc ccatcacaac actaatatca ctcataacaa tgcctcctca aatctgcttt
     9001 aaggatagca aagatttttt tataattcaa tgtaaaaatc gaacttaatc aagttaaagc
     9061 ataaaatagt tcgttaaaat tcacaaaaaa gaaaaaaggc cgaattcatt tccagcctct
     9121 ttcctaaatt atattagttt aactccttca acatctgggt gtaaacggac tacttttccc
     9181 tttagccccg cagcatgtac tgcctgttca aataatccgt aatcgtcatt atcgataact
     9241 gtcattactg ttggtccggc gccgcttaaa tatgttgcta gtgctccatg tttttttcct
     9301 aattcacgaa tttgatctaa ttctggaact agttctttgc gatatggttc atgaaagcga
     9361 tctgcctcca ttaatttaaa cgctacatca tagtttttag caaacaaact agcaacaaag
     9421 gtattagcaa ccgcgctcgc atgaacagct tgggaatatt ctagttgata tggcaaggca
     9481 gctcgcgcat cagctgtttt tagattataa ggcgggatat atgcagcaaa agcatagggg
     9541 aataagggcg cttcaatcgc agaaaaatgc ccattaatat gtgtccccac tactaatccc
     9601 cctagaatag tcggtgcgac attatcagga tggccttcaa tctggctggc aatctcaact
     9661 ttttcttcct tgctaaggtt caggttctta agctgatttg ctaattcgat tccagcaaca
     9721 attgcgcttg aactacttcc taatccatgt gctatcggaa tttcactgac tacccgcagg
     9781 tgctgtggca gcaaatccgg tgcaacactt aatgccgttg ttacaatcat attcgtctca
     9841 tcatgaggga gcttcccaag ctggtgatca acttgccagt tatcgcttgg accaaggact
     9901 tctaatttta aatacaaaga gactgcaatc ccaatcgagt caaatcccgg accaagatta
     9961 gcactggaag caggtgcttg aataatcatt atacttcctc ctatcccatc actttataag
    10021 ccgccgacaa gttaattgac tgatcattag ccactttagt tagtaatgtc tgtaattgtt
    10081 ctttgctcat ccggtgagta atgattgcaa tgtgcgcaat tttgccatct tttgtttggg
    10141 ttatttcacg aaaactagca ttaatattcg tcatcatctg ggttagcttc aacatttgcc
    10201 caggaacatc cggcaaggtt aacgataaat aatatggata ttttatatca gcaagttttg
    10261 ccggaatata aggttgttgg taattattaa agagattccc attagttccc aggataatgt
    10321 ttttcgttac cgttgtaata tcacttaaca cactgttagc agttggcaag ccccctgcac
    10381 cgcggccata aaagagcgta tcaccgaccg cttgggctgt aaccattact gcattaaatt
    10441 cattattgat tgttgctaaa ggatgatcac gggggattaa cactgggcca acttcgacaa
    10501 atactccatt attaaccagc ttggtaatcc ctagtaattt aattacgtat ccaaatgacg
    10561 ctgcttgttg aacatcagcg tcattcaatc ggtcaatccc ttctaccgca atgtccttaa
    10621 tatctagttg agttccaaat gcaaattgac ttaatataat catcttgtaa gccgcatcct
    10681 tacccgtcac gtcattggtt ggatcactct ctgcaaatcc cagctgttgt gcttgggcaa
    10741 gtgcttggtg gtatgaccat ccccgctgac tcatttgcgt taagatgtaa ttcgttgttc
    10801 catttacaat tccctttact tcagtaacct tatctgccgt aaagctatta gcaatcgtcc
    10861 gcaaaatagg aatcccacca gccacactcg cttcaaacat taagtcacag tgattttcat
    10921 gcgcgacagt catcaattct gggccataag acgcaatcaa atccttgttc gctgtgacca
    10981 cattcttatg attttttaat aaggttgtaa tatattcttt agccggatga ataccaccca
    11041 taagttcaac gacaattttt atttcatcat cattcaagat ttcatcaaaa tcagttgtta
    11101 aagaagtttc atcagcatac ttattatagt taccaaggtt tcgaactaaa gctgttttaa
    11161 ctgttaactt gcacccagta acatcgataa ttttatccgc attttgttga accatctgta
    11221 agactcctga cccgaccgta cccagaccga gcagtcccag tttaatgttt ttcattttcc
    11281 cgcctcagtt tctcattgtt ttttcatttt cagtattgta ccatagcata taagaaacat
    11341 acaattaaaa taaaatcacc tttgaaattg gaggaattat catggactac cgtagcactc
    11401 agggagactt atcaacgatt ttaaaatcac caactgctat cttacaagga ctttctccag
    11461 acggcggtct ttatgtaccg cttcattttc ctcaaccaac ttataacctt gcaaccttaa
    11521 tttcgttgcc gtaccaacaa cttgctgcaa ctattcttaa ctggtttttt gatgaattta
    11581 cgagcgacca actactgaaa aatgcaaata ccgcttatgg tagtcagtgg gataaccgtt
    11641 taattgcccc attaacgccc aaacacgcca gcaattatta tcttgagctt tttcacgggc
    11701 cgacactggc atttaaggat atcgccttac aaatgttacc ccaattagtg tcacgtgctg
    11761 cacaaaacac ccaactagaa aaacaaatcg ttatccttac cgcaacttct ggtgatactg
    11821 gaacagcctc aatgcgaggg tttagcaatc aaaaagacac acaggtaatc gtcttctacc
    11881 ctgctggcgg ggttagtccg gttcaattac gccaaatgct ggggcagcct ggatcaaacc
    11941 tccacgcaat cgcaattaag ggtaattttg atgatgccca aacaagcgtt aaacatattt
    12001 tcaacgatca agcatttaat gaccgccttg cgcaaaataa taactgcttt tcctcagcta
    12061 attcaatgaa tatcgggcgg cttatccccc aaattgtgta ctattttgct gcatacggac
    12121 agcttgttca tacaggcggg atccaactag gggagaaagt taatttcacc gtgccgactg
    12181 gtaattttgg cgatatcctc gctggttact acgctaaaaa attaggctta ccaattaata
    12241 agctcctgtg tgcttctaat gaaaacaatg tattgaccga ctttttcaag agcggaaaat
    12301 atgagcggcg acgcaacttt tacctaacta actcaccagc aatggatatt ttagtatcaa
    12361 gtaatcttga gcggctcctc tttgatcttt atgatgaaag ctgcgtaaca gttgctaaat
    12421 taatgaagca attagctact gacggtcact accaggtaga ttccaccgta ttaaataagc
    12481 ttcaggagca atttgtggct ggttttgcga ccccagatga agttgaagcc gaaattaaac
    12541 gagtatattt aaatgatgga tatgttattg acccgcatac tgcagtggca tcacatgtaa
    12601 cacatcaata tcagcaacaa agccatgaca caactcccac agttatcgtg tcaactgcca
    12661 gtccatataa attccctgaa accgtctacc acgcactaac caaccaaaaa gttagtcaaa
    12721 gcgggcttcc tgctcttcaa cagttacatg atcttctggg agatcagctt agcgctggtg
    12781 tccaagcgtt agtagaccaa acgccgcgcc aagaaaaagt cattaaccca gcagacatgg
    12841 aaacattgat aagtaaaatt ttaaacttaa agtaagctac ccttgacgct gccggtattc
    12901 ccgtagtgtc atccctaccc gttccttaaa tattttacta aaataggcac tcgtactaaa
    12961 tcccgcccgc aaagcaatat ccgtgatcga aagctccgaa tgccgcaata atttctttgc
    13021 ctgctcaacc cggtaattta ataagtattc aattggcgtt tggtgaatgt ttttcttaaa
    13081 tgaccgaata cattctttgg gactaatatt gaccgcagtt gcactatcat taattgttac
    13141 cttttccgca tagtgtttaa atacgctaaa atatttttgc tgcgttcacg tgggataacc
    13201 gtcaattgct ggtgttgttc ttgaaactta atttcagcaa ttagtgtcaa ccaagcttgt
    13261 gaaaggagat tgcggattta aaattcctta tcaggctggt ccgccacatc tgttagctgg
    13321 tggagtaagg taatgaattt tttgacggtc gggttagatt cttgaatcac caaaacttca
    13381 actgaacgat tttttaaaac aggatttagg tatttagtgt aaaaagcact attgaaatac
    13441 ctgccaagca gaaatggaaa tgtcacaatc atgtcctaat gctaccggtg ggcacaaggg
    13501 atcagaaagt tctttattat gatgacatgg tacaaatcta caaaatggct aaccaggaaa
    13561 tctagcttat gttacgatta ggaattattg gaacccatac tatttttgac cagatgattc
    13621 atgcagcaca agatactggg aaatattaac ttactgttgt atattcccgt aagcttagca
    13681 ccgcagaagc atttggcaat aaatataggc ttcgcgacac gctaataatt gacagtattt
    13741 tcgatactaa gaatgtgact tatcttaata atcaggggga gtattcaagt tatcaataac
    13801 cactacttag ataacaccat gtttgacgag ttaaacgatt ttgcacaact ctttactaac
    13861 cccgaatcgc cacagcagca ggataattat caacgatggc ttgaactagc taaaattgtt
    13921 aatatgactc tataccgtct ccgtaaatct gcaaatatta tttttccaag cgactactaa
    13981 ttaatcaact cattaaaaac gacaacttaa gatgatattt tagaaatcac aaaaagggtt
    14041 ccagagttcg ttaccgagca ctggagccct ttttcggcgt tatttatacc gctgcttcat
    14101 ttgttcttta gtctgcattt ccttctgatt tagcaattcc atcacgtaaa gttgccatat
    14161 caacttcact cgcccgaaat tctttattat caatcggcaa atgctgttcc aaattatcaa
    14221 agacttcaaa actcccggtc aatttggaag catcaaacgc caggagatgc ccagcaaatt
    14281 gccgatcatc gctaataaaa tgaaggtgcc agccagctgc cgtaatcgtg ccaaaaatgt
    14341 ctggtgcata ataaccgata atggtcccag aaatattttc agccgtaaac tcaggttggt
    14401 gttgcgcaac atcgagtaaa gtcgggtatg gcttttcttg cttcggagca atccgaattt
    14461 tgacgtgctt aaactcacca ctcaattgta agaatgcaaa aacattagca agctgatgtt
    14521 ctttaacaaa atcattattc agtttagcaa agtttacatt ccttaatgtt atatcctgtt
    14581 gttcagcagg aaaatggact gaagcaaatg gcattgtagc atccatatct gtaatgcggt
    14641 taacttgacc acttgaaacg gcctggtaca cttcattatt caggataaca acctcaccgt
    14701 ctaatccagt aaaagttcca attcccatcg aaccatgttt taacaaatca ctgacagtaa
    14761 ttgtgccatc aaaatttcct gccatcaacg cagctaacgt tccgtgttca tataatgttg
    14821 tcataatctt tgttcccctc ttagccaagt tgtgaatcaa tcaagttggc agctaattct
    14881 ttattgttac tgtaatcaac tggaacatct accacaaccg ggccatcaat attaaaggct
    14941 tggctgatta ccttagtaag atcagccggc tcatttaccc gtagtccagt tgcgccaaaa
    15001 ctctcagcat acttaacgat atcaacattg ccaaacttaa caccagctgc ttgggggtac
    15061 ttcatctctt cttggaactt aaccatatca taatagccac catcattcca tacaatcgtt
    15121 acaacattaa gatggtattg gacggctgtc gctaattccg ccccagagaa gaggaagcct
    15181 ccatccccgc aaactgccac tgatttatgt tcgggataaa gcatcgctgc aaccatcgcc
    15241 catggcaagc caacgcctag tgtttgcatc ccgttactga ttaacaagtg tcgtggttgg
    15301 tagcagcgga aatgtcgtgc catccagata tagtgggaac ccacatctag cgcaacgtgc
    15361 atgtcatcag taacattttc ttgaattgca tgcacaaccg ctaacggatg actggcatca
    15421 tcacttgctg gtatttgaat ctttttatct tggtcaagtt cttgcttata tttagcaagt
    15481 tgctcagtgg ctgcaacagg atactcatac ccctttagta acttatcaag ctcagttaag
    15541 cttgtagcaa tattaccaac taattgcata atcggtgtaa agtggttatc tatttgtgct
    15601 ggcaaagtat cgaggttaac aatccgcaaa ttaccttctt tattccaatt ctgcggttca
    15661 tattcgattg ggtcatatcc aacagtaatt actaaatcac tttgttggag caattgatcc
    15721 ccaacttgat tacggaaaag tccaattcga ccaaagtatg attgttgttc taagtcacgt
    15781 gataccactc cagccgcttg atatgtttca acaacaggca atgaataatc acttaataat
    15841 ttgcggagag cagtcgtaat tttttcatcc gcgccccgtt gacccactaa gataaccggc
    15901 attttactat ttttaattag ttcgactagt ttttgtaagt cgtttggatc agcaggcccc
    15961 atcttaggtg tttcataaat tggcaatggc ttttcagtta cctcagcatc atcaacgtct
    16021 tgtggaaggc taacgaaagc tgctccctta cgtgcatctt gacttgcttc aaatgcatta
    16081 gccataatct ctgaaatgtt attaggatct tgaatttcag cgctatattg cgtaatcggt
    16141 gccataattt cagttgaagg cgtgctttgg tgggttgcac ggtgaagatc tttccgttgt
    16201 acttgtcctc caatcgctaa cattggatct ccttctgcgt tagctgtcat gatcccagtt
    16261 actaaattac caactcctgg gccagatgta gtgatcgcga cccctgtttt tccggttaag
    16321 cgaccataag cttgggccat aaacgccgca ttttgctcat gccgagtaac aattaattta
    16381 ggtgcatctt cactgtcttg accatctagt ccttcaaaca aacgatcaat cttcgctcca
    16441 ggaataccaa agacgagatt aaccccgtgt tttcttaaac tatcaataac aatatcggcg
    16501 ccatgtagtt tcttttccat tagccattca cctctaccta aattaaactt ataaaacgat
    16561 atagctctac tgtagtcctt attttataat ttcacaagaa aacgattaag ttcacatagc
    16621 ggtatatcaa taacttcaac ccgctaacct tgaaaagttt gtgaaaaaaa catcgatgta
    16681 cgttattgca caatcgatgt tttgtgttgg ttatttagaa taatccagta attttaccat
    16741 tatcgtcaat cgtcatgttt acagcagctg gttctttagg gaggcctggc attgtcatca
    16801 tattaccagc taaggccacg acaaagccgg caccgatctt tggtaccaat tcccgaatat
    16861 ggaaagtaaa gtcagttggg gcacctagtt gtttttggtc atctgtaaat gaatactggg
    16921 tcttagcaat acatactggc aaatcattcc atccatactt agcaaatcgc ttcaattgat
    16981 tttgtgcttt acggctaaat gatacttctt tagcgccata aatctgctta gcaatcttct
    17041 ctaacttagt ttgaaggtca tcaacttgaa cgtcatagat atgagtaaat tcacttggac
    17101 tatcagcaag ttcgactact ttattagcca aatcatgggt acctttaccg cccttggccc
    17161 aagcatcagt caaaatcgct tcaacatttt gcttagcgca atcatcctta atcatttgga
    17221 tttctttatc ggtatcactg acaaaatgat tgattgcaac tacgattggt aacccatata
    17281 attgcatgtt cttaatgtga cgattaaggt ttgccattcc ttttttcagc gcatcaagat
    17341 tttcttcatt taagtctgcg agcttggccc cgccattgta ttctagcgct cggacagtag
    17401 ctacgatgac aattgcatca ggatgcttac caagaacacg ttgcttaata tcaaggaact
    17461 tttctccacc aaggtcagcc ccaaaaccag cctccgttac agtatagtca gaaaggttaa
    17521 gggcagtttg cgtcgccaga acactattac acccatgcgc aatgttagca aatggtcccc
    17581 cgtgtacaat tgttggcgta tggtctaaag tttgaacaag gttaggcttt aatgcgtctt
    17641 tcaagataat tgtaattgca tcctgaaaat taagctgacc aactgtaacc ggttctttat
    17701 cgtatgtata tcctactaca attcgactaa tccgttcttt caagtcatga aggctagttg
    17761 aaaggcataa aattgccatc aactcggagg cagctgtaat gtcgaagccc gtttcacgtg
    17821 gaacaccagc cattggacca ccaagaccgg taactacatt tcggagagca cgatcgttaa
    17881 cgtcttctac ccgtttccag ataattcgcc gtggatcaag gttcattgca ttatcacgca
    17941 taatatagtt atcaattaaa gcggccaaag tattattagc acttgtaaga gcatgcaagt
    18001 caccagtaaa gttcagatta atatcttcca ttggaacaac ctgactatat ccaccaccgg
    18061 ttgcaccacc tttgattcca aaaacaggcc ccatcgatgg ttcacgcatt gcaatcgttg
    18121 tctgatagtt taattgattt aatgcatccc ctaaaccaat taggacagtc gactttcctt
    18181 caccagcagg agttggattg atggacgtaa ctaaaattag tttatgtttt ttatcaggta
    18241 acggctttac atttaaatca attttagctt tgtacttacc atattgttcg atttcgtctt
    18301 ctgaaagtcc tagtttctcg gcaatttctg taattggttc cagggtcgct tggtctgcaa
    18361 tctcaatgtc tgtcatgaat atcagcttcc tttctttagg cctatcttaa tttcattata
    18421 cactaactca agactttttc agctatttaa caaaataagt tcgatttccg ttaactttat
    18481 tcaactaact aacgtatatt gttcggataa ccaaaaagca aaaaataaaa tcccgctatg
    18541 gaactttatt ttttacttac ttcttttttt gcaccacgaa tgggttttac gcctaataca
    18601 tcaagtaaga aggtaaagat tggtaccccc acaatcaatc cccatgtacc aaagagatgt
    18661 tcaccaatca gcaatacaat aaaagtataa aagattggta gatctgtccg gctagacata
    18721 aacttaggat ttaagacgta ggcctccaaa gtatggatga tgataatcat gatgataatg
    18781 taaaccacat cgcgaattcc accgactgag taaccaacca ttgccaatgg gattgttgaa
    18841 ataattaccc cagcaaccgg aaccaaacta aagataaata caatcaatga tagggcgaat
    18901 atctgtggca tccgcataaa taataggcca atcatggtaa tcaccgtatt gcaaatagca
    18961 ataaagaatt gggcctccaa tacaacccca aaagtattga caaatttctt gccaaaataa
    19021 tcaatatcct ggaaaaacca gccaaaatca ctatctaaaa agctatgaga aaattcattc
    19081 atctgtttta attcaagcgt atagaaaaag ctcaagatta aagacattac aaatgaaacg
    19141 gtgattgcac caatacttgt caaagtgcta actgcgattg ttatcccatg tcgaacctga
    19201 ctcataatag tagcggtact tacgtaatgg ctgacataac gatatatcat cgtcgcttga
    19261 tgcgtactat agaaatgaac tactgaatta accattttaa caacttgccg agacaaaact
    19321 ggtaaatagc gtgtcactcc taaatacaat agaacaatta acaacacata ggtaacgatt
    19381 acaattaaac ttgtcgacat tcgtggtaac caccgctgga cgagtcttac ccaactaaca
    19441 acaaggtaag taagaataaa cgtaaataaa attaaattca tcattgatct cattaaccag
    19501 agtacgacaa tgattaataa taagacggtg aaacgccgta gttttacatt ctcaataaaa
    19561 tgcttccagg cattcgtcat tcaatcatct ccctattttt cttactaatt agcatagtag
    19621 caagctttca ttttttcagc aattagttta tcgctttctt atgaaatgtt ttttataaat
    19681 tgtcttgaaa cacttttatt ttaagggtgt tataatgaat attattattg cagaaagaag
    19741 gatacgtttc atgttagaaa agacgttcta taagtcacta ctaaagcact cgtttaacat
    19801 tccagtaaag atcgtatttt gggatggatc aagtgttatc tatggtgacg gaactcccga
    19861 ggtaactatc acttttaagg aaaaaattcc aatgcgtgat attaccaaga acgcctcaat
    19921 tgcacttggg gaagcctaca tggataagaa gattgagatc cagggtagca ttcaagaatt
    19981 gatcgaatca gcctatgaaa gtgctgatag ttttatgcgg agttctaagt tccgcaaatt
    20041 tttgcctaaa caaggccact cagaaaaaga aagtgaaaat gatgttcaaa gtcattatga
    20101 tgtggggaac gacttctaca agttatggct tgatgatacg ctaacttact catgtgctta
    20161 ctttactgat ggcaaccacg atgatcttac aaaggcccaa gttgacaagg ttcatcacat
    20221 cttgaagaag cttgatccaa agcctggcaa aacattgctt gatattggat gtggttgggg
    20281 aacattaatg ctaaccgctg caaaagaata tggcttaaaa gttaccgggg ttactctaag
    20341 cgaagaacaa tatcgccttg ttaaggaacg gattgaaaaa gaaggtttgc aagacgttgc
    20401 cgaagttaaa ctagttgatt atcgtgaact tggtgaccaa aagtgggatt acattacatc
    20461 ggtcggaatg tttgaacacg tcggaaaaga aaatctaggt ctttacttta aggacatcca
    20521 aggttatctt accgatgatg gtgttgccct gattcatggg attactcgtc aacaaggcgg
    20581 cgcatataac ggatggatta acaagtatat cttccctggc ggttatgtac ctggtcttga
    20641 agaaatgatc ggtcacattg aagaaaatca tatgcaaatc gctgatattg aaatgcttcg
    20701 tcgtcactat caacgcaccc tcgaaatttg ggatatgaac tttaatgaac atcgtgctca
    20761 aattcttgat atgatgggcg aacgttttac acggatgtgg gatttatacc ttcaagcatg
    20821 tgctgcatcc tttgaatctg gaaatattga tgttattcaa tacttaataa ctaagggtcc
    20881 ttcaggtaaa aacttaccaa tgactcgtga ttacatgaca aaatagaaca acctaagatt
    20941 agttcaggac gaaaaatatc tcgttctgga cttttttgtt actctaaaga cagagcgtag
    21001 agctagtgag aaatctttat tccctccagc cttttcgcaa acttatactt tgaaattctt
    21061 taacattatt cgtgttttag tttaaaaata ggttgattta aattaaaatg ttcgttatta
    21121 taatgacaca ttcgaatgta actgttctat cactttcaga atttcaaagg agtatataaa
    21181 ttatgcaaag tcaattttca actgttgaag aagcattaaa ccaattagta aatggtggtt
    21241 atatcatctt agccgataat gaggatcgtg aaaacgaagg tgatttagta gctttaggtg
    21301 aaaatgtcaa cgctgatact atctacgaaa tgttgaacga ggcaaatggt ttgatgtgtg
    21361 taccagtaag cgaaggtatt gctaaacatt tagcgtttaa gcccatggta gaacatagca
    21421 ccgacccaca ccaaacacca tttatggtta ctactgatgg taccttagaa gctaccggtg
    21481 ttactactgg tgtttccgct tttgaccgcg cagcaacgat tcggcaaatt gccaaaccaa
    21541 ctgcccaagc atctgacttt aatcatcccg gccacattca acctctttac gcccaacctc
    21601 atggattaag agatcgaatc ggtcataccg aagcagctat tgatcttgcc tatttagcag
    21661 gaaaggcacc agttgctgtt attatcgaag tgttaaagcg cgacggcacg atggctcgtc
    21721 gtgatagtct gtcagtcctc gctaaccgag ttcatgtacc atttattaca atcaatcaaa
    21781 ttattgagta tttagatgta aagggaatcg attatgccgc tgacctcgct aaagtaaatg
    21841 cttaattaat gtattgtatt ccctttcatt ttcgattacg ttaaaatata gacataatta
    21901 cctatgaagg gatgtttaat catggacggt gcgatttttt cgtttaataa tatctttgtt
    21961 aatacaaata agttatcctt tactgcatgg caacgttttg caatgtatga atttgggatg
    22021 ggattacctg gaaaattagc ttcccaattt gataacctta ctccttcgca agggctctcc
    22081 ctagtcttag cccattttaa tgctaatcct gcccctagcg aaaaggcttc aatgattgca
    22141 gaatggcaaa aatttcttaa cgaagaagcg gatagcctaa gtgaaaaaga tcaacttcca
    22201 gggattaagc gtcttttact aaatctctat gatcattacg ttaaaattgc tgttttagat
    22261 actaatgggg atgtgcaaaa tgtcctcaaa caaattggcc ttgataacta tgtcgatagt
    22321 atcgttaaga ctaatgataa agaaaaccca tatctaactg ctgttaatca attaaacctt
    22381 atcggcgcta attgtatagg agttggaacg acagctcatg atatcgagaa tattcatcac
    22441 ataaatgcga ttgcaattgg tgttggtgat gccaaaacat tagcaagtgc agattatcaa
    22501 gtagtacaag ttggtgactt acgctaccca atgctccaaa agatttggga agataagcaa
    22561 taagataaag cctaagatta attcagatta acattctttc tgaatcaatc ttaggctttt
    22621 ttgatacgcc gtttgtaaaa ttaagttaga aaaaaaaaag ccatttgtga tagacttttg
    22681 agtatcccta atcaaaagaa aggcaatcac aaatgaccta taaacatctt accacacgcg
    22741 aattaactct cat
//
