LOCUS       c00059_gnlPro..        17052 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KECIDAGE_59.
ACCESSION   c00059_gnlPro..
VERSION     c00059_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 03:45:08
            Original ID  :: gnl|Prokka|KECIDAGE_59
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 95814
            Orig. end    :: 112866
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17052
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[105814:109300]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13486
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..17052
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17052
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(772..2976)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_36C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_36N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Melibiase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_74"
                     /sec_met_domain="Glyco_hydro_36C (E-value: 1.5e-20,
                     bitscore: 66.0, seeds: 330, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_36N (E-value: 2.1e-48,
                     bitscore: 157.5, seeds: 284, tool: rule-based-clusters)"
                     /sec_met_domain="Melibiase (E-value: 9e-125, bitscore:
                     408.6, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALLLTVALLLGCVTVSSQDKDTGIITVSTNDLSMVFSISPDKK
                     VVYNYFGDKFQDVSPFLHKKYKEQPDNGIGYAPVIYPAYGGRFFLNPALKLTHDDGVQT
                     TELIYAAHQVKNIDNNRIETVIQLKDPLYPVFVNLNFTAYQKENVICQSVSISHQEKNK
                     LAVENIASAYLPLHADSYYLTHFHGAWASEMQLVEEQLTPGVKRVESKKGIRTTQSENS
                     SFLLSLNGPANEDMGEVYAGSLAWLGNYLSSFEIDECGLLHVMSGMNDFASTYNLEPGK
                     TLQTPEMVWTYSSTGKGQVSRNLHDWSRNYALAHGDQELPIVLNSWEGAYFDFNEKTIT
                     DMIDDAAAFGVEMFVLDDGWFGNKYPRNSDKVGLGDWQVNRKKLPRGIDYLAKHAVSKG
                     LKFGIWIEPEMVSPKSELAEKHPEWIVKSGKRDIIPMRNQWLLDLSNPEVQDFVVKTFD
                     EVIALSPDISYIKWDANRHVDNFGSEYLSKENQTHFWIDYTKGLYSVYERIRAKHPDVL
                     IQLCSSGGGRLDFGALKYHDEFWASDNTNSLDRIFIQYSTNLFFPAKATAAHVSTTPNH
                     QTGMMAPLKFRFDVAMTGRLGMELQPEDLTGDELPFAEQAIKNYKRIRPIVQFGDLYRL
                     KSPYDGTGWASHMYISKDKKESVFFAYSLKYHGRTTFFETRLKGLDPAKMYKITELNKA
                     GNSTFYGDGQVFPGDYLMKAGISLTIGNTYESTVLLITEQ"
     CDS             complement(3155..4375)
                     /locus_tag="ctg59_75"
                     /transl_table=11
                     /translation="MEYIGLHEDKISLADIIKYLSLLKGNMDELNLLEFKTIKGWLVYS
                     LSLVLLLCIPCVIILLITGLLSGNIDSGLLLAVSFIPFLFILPLTLLLTFINNYRKPKK
                     LRELMQTVLMRYEWDGPINQTGRLQLECRKDHFLFRTEVLRQMNPKGRNVSLIFISVPF
                     YVPIEKELIHAEDIIAYLKGKSLFVIEPDMACLGMSFKMFQKLDLREDIDQLIYVMKRF
                     SLRPGTLFKAQDITLKVPETLEIQALFIFGQKIDQRFLNWANLMLDAGFVSDNMKIMAE
                     QASLTLPQKELKKRVEVIFLEFNLYFSKETVLNNYLIFLILEEQEERRSVLEIIQCLAS
                     LYQSSRLPLLQEYDLLYKAKRALDETGEQNFWTADPPLTVDNVDTYILTYLTRRLADLI
                     ASREKDQ"
     CDS             4507..4698
                     /locus_tag="ctg59_76"
                     /transl_table=11
                     /translation="MKKPQYKDKPETSVCQVFYRQYMLSLSGIVAKNCFRTQNFIQYRQ
                     KLLILTVKTAKSIEKDVL"
     CDS             complement(4676..5443)
                     /locus_tag="ctg59_77"
                     /transl_table=11
                     /translation="MAGVALAVVSCSISALLLYYYGHTGWLVAWLDSLVSVGIFCVSGF
                     LFWYVTGILRPLQAQIALAVGVLIISVTGGYMAGALVYPDRMDWFASTIPFRILLGLLG
                     WIILAQWYYIRWKELQMEIQEEQRKEENAPAETGVSSPEEEAILDRISVKDGSRIHLIH
                     LEELLYIQASGDYVALFTTDGQYIKDQTMKYFESHLPANLFIRIHRSCIVNSEQIMRVE
                     LFGKESYQVRLKTGVCLRASLTGYKLLKERLSL"
     CDS             complement(5485..6234)
                     /locus_tag="ctg59_78"
                     /transl_table=11
                     /translation="MNLRKNLFWAIPFIVVGVVWIMRNTGMITDDLFHIIVSWQMLVMY
                     IGIGSISRRHYIGGLITFLVGAAFLLPRLGWMDSDWLQVYWPAAFVIVGLMLIFEPRKK
                     NSYHYNSRREDTGGEDIRGNAVAGKVKSDFINTDGYVESDNTFGYVEQIILDPVFKGAR
                     IRTVFGGTVLDLRKTKLDSAKTYIDIDCKFAGVEIYLPGDWAVNFHGSPIMGACEDKRF
                     NASMEMDKEHILVVRGIVMFGGIEFKS"
     CDS             complement(6640..7224)
                     /locus_tag="ctg59_79"
                     /transl_table=11
                     /translation="MTTKLKDLFDTFLNIAASSQKLGINLIRVAILIIFVWIGGLKFYN
                     YEAEGIVPFVANSPFMSFFYAKSAPEYKEYKLKEGEFNEAKHQWHVENNTYIFSHGLGI
                     MIMAIGILTFLGIFSPKIGLIGSGLAIIMTLGTLSFLVTTPEVWVPDLGSGEHGFPLLT
                     GAGRLVIKDTAIIAGAIVVLSDCAQRILKKK"
     CDS             complement(7402..8511)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_80"
                     /sec_met_domain="Radical_SAM (E-value: 4.5e-09, bitscore:
                     29.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCFYAEDMDKKEKDLTFEEIKTISETAGQFNRLWVSGGEPTLREE
                     LPEIIEMFYKNNEIKDVNIPTNGLKPDRIVAWVKQIRQNCPELNINLSLSLDGFGDTHD
                     IQRGVPGNFYKAMGTLKLIEKNFADDGRVLKNLATVITKYNENEVEDLMIWMLGRFHLS
                     NHIIEAARGMTRDDGVKVLTEPTLRALQDKVVPIYNVYGERMAEETGGFRKPIARFFYL
                     GFIRTLYNVRATNIDHPTPWGMDCTAGETTLVIDYDGRFRACELREPLGNVKDYDCNIA
                     KIMESDAMKQEIAAIGHGDKANCWCTHGCWITSSLVFNPRKMITQVYKGYREMKKLNRP
                     LNISEELLQSIERKYALDEQKLVELGVRN"
     CDS             8857..9702
                     /locus_tag="ctg59_81"
                     /transl_table=11
                     /translation="MEDNIPKFDLPVDFIVGNSITGEILNQYGRFPCKIKAGIFVLCVQ
                     GTVHATVNLTEFTIRKNDFITLPPGCFIQIHEVSDDVKLCFAGFSSVFVSHINYIKTIT
                     NYLPVIFDSPIMPLPEHISLLYQQAFDLLINAYSMPKTIENKEIIKAIFTIFMQGVIEL
                     YRNHTPYSNAPMTRNMEICREFVQLAMENYTKEHSVSYYAKRLNITLQHFCYVIKKVSG
                     RTALDILSNIIIMDAKAQLKSTDMPVKKIAFALGFDNLSFFNKYFRQHVGMTPQEYRES
                     "
     CDS             complement(9764..9898)
                     /locus_tag="ctg59_82"
                     /transl_table=11
                     /translation="MLLVFLICYTTLISILTIDKLENTCIFVLWFFHNSIRFKVNKVG"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_83"
                     /sec_met_domain="Fer2_3 (E-value: 5.9e-26, bitscore: 83.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1.9e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.1e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKSPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANSIAIPRADAEMAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(10784..12727)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 195.7; E-value:
                     4.7e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_84"
                     /sec_met_domain="FAD_binding_2 (E-value: 6.6e-60, bitscore:
                     195.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 6.5e-38,
                     bitscore: 122.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWKNYKDHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRMIGLNKVKMYTRHEMLDVVKVDGRARGIIARNLITGQIERFSAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDYQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSDAINRLGKDVVKAKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFAEAEKGIKDRIKKLMSIKGKESVDSIHKKLGHI
                     MWEHVGMARDAKGLQEAIQMLKELKKEFWSNVYIPGEADNLNVELDKALRLADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             complement(12761..13486)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_85"
                     /sec_met_domain="SucD_FumR (E-value: 1.5e-75, bitscore:
                     245.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSVSGLFLVLFLLFHLSMNVAAAFSGEAYNMI
                     CSLLGANWYAVAATLVLAAGVVIHFVYAVLLTLQNRKARGNDRYAINARPKGVEWASQN
                     MLVLGIIIILFMVLHFSQFWYKMMFAELLGNHMVTLCDGTTTVSPQDGAAFINYYFQGN
                     ILNTVLYLVWYVALWFHLTHGFWSAIQTIGWSNTIWMNRWICISKIVATVICVVFAIIT
                     IVFYLNGVGGDYVAVCAGH"
     CDS             13725..15122
                     /locus_tag="ctg59_86"
                     /transl_table=11
                     /translation="MLQRKMLSFLFMMIFIPSVRAQWKDSTRFINKEHEFETTYNKISE
                     NKVYQMLRVPVPLFAISAITYGQGDKFRTLRNTHTPNFHYRYDDFLQYTPLLAVYGMKL
                     GGVESRSSWPRMIVSNAFSATIMAATVNSMKYTIKRERPDGSKNNSFPSGHTATAFMAA
                     TIMHREYGLTRSPLYSIGGYTVATATAFSRQLNNRHWLSDVLAGAGIGILSTELGYFLA
                     DLIFKDKGLNLPDKLRESAPKGGRPSFLEFAVGYSIINGSIEVGKNIRLSSPGATNVSV
                     KGGYFFNPYFGIGGEITALASPMAFDMSLYTGTTPSTKYDITRIHADPTGVFTFTAGPY
                     FSLPVASKLLLGTKFQAGYSYLVKNEVEMDLQEKHPPYGTINNIAFMKGNGSSNYVLRT
                     GISATGIVSRNLGIRMFVDYDYTFLKAPYEILTSLRDSQPVYGESHLSKHKIHYFTIGA
                     TVTALFW"
     CDS             complement(15126..16949)
                     /locus_tag="ctg59_87"
                     /transl_table=11
                     /translation="MNKTILLVVFCFSLFVSGYSQGIRFDSYPSHPRLLVKKGEEQKIK
                     SDLALNPEMLRLHNYLLGQCDDLITTPVLAYKKEGKRLLAVSREALRRIFYLSYAYRMT
                     GEDKYRLRAEQEMIAVCSFTDWNPSHFLDTGEMTMAVAIGYDWLFDRLSPDARRLVQEA
                     ILNKGFAPSRDKRYNWFLRATNNWNQVCNAGLVYGALAVLEDHPEEAREIIERALSTVG
                     LTLKGYGPDGAYPEGYNYWGYGTTFQVLLNAALESALGTDGGLSSAEGFLASARFMQFM
                     TGTTGKCFNFSDSRESVFALPAMYWFADKLQDPTLLWNEKDMLSRAELSFSDEESRFLP
                     LIPIYGSQYKMNELVPPAMKLWAANGQTPVVLVRTGWENGEGFYLGIKGGTASTSHAHM
                     DAGSFVFDASGVRWVQDLGMQEYYSLEKENVDLWNMSQNGQRWNVFRYNNLAHNTLTVN
                     GKYHDVNGFVPVTNIYSEAHKLGASLNMTDLFGGELENAVREVALINEKYLSVIDRVKA
                     GSQPATVRWTIVTGAIPRVLDSHMVELTKDGKCMQLIVDSPSVTSVSVLDNVSKNSYDA
                     SNEGTCRIVFDVSLESGQESDIKVRLVPAAD"
ORIGIN
        1 cgaaaaatac cttaggagac tttaccattt ttccttttaa agcaccgtgt gccttagagt
       61 cgcgtgtcaa cgaatcggca acgccgccga agcaaaccaa tgaaccgata ttattacggt
      121 cgcctttccc catatcgata ccggtcttcc agtcggagtg ttccactgaa ccgatgacaa
      181 aacctttacg gtcgtcgttg ttgaagacag tcgctacttc atagctacgt aattgatcga
      241 aagtgagcgg atgagactga taacgtatcc agcaatcgtt atcgaaaggc tggaataacg
      301 cgcggttatc accttcagcc aacacggccg gcatgcggtc gatagtaacc ggggccatat
      361 aattcgattc aacgtcagcg gctcctccct gaagagtaaa ttccgtcagc agataatctt
      421 tctccggata gatgtagaaa gattgtacaa gcgtaggcag gttgctatcc gtgtaggtca
      481 cctgcaacaa tgaaccctga ccgaaagcat cgctgatagc ggtgactttc gaactgctct
      541 ttttgtagtc acgggtcgtg accaacttat tacccaactt gtaggaggca taaaccccat
      601 cggaaagaag ctggttctcc ttctcgatac ggtggccttt ctgcacctgg tcatagctaa
      661 ccgtccactt tcccgaagaa acggatgatt cgccgcagga tacaagcagg gcgagcaata
      721 gcagcagatt taaattgatg agtttcatgt attgataatt tatagatagt ttcattgttc
      781 cgttatcaac agaacggtac tttcataagt attccctatc gtcaggctga ttccggcttt
      841 catcagataa tcaccgggga aaacctgacc gtcgccatag aaggtgctgt tcccggcttt
      901 gttcaactct gtgatcttat acattttagc tgggtccagt cctttcaatc tggtctcaaa
      961 gaatgttgta cgtccgtggt atttcaggct ataagcaaaa aacaccgatt cctttttatc
     1021 cttagatata tacatatgtg aagcccagcc ggttccgtcg taaggagatt tcaggcgata
     1081 gaggtctcca aactgtacga tcgggcggat acgtttataa ttctttatag cttgctcagc
     1141 gaaaggtagt tcgtcgccgg tcaagtcttc gggttgcagc tccatgccca ggcggcctgt
     1201 catagccaca tcaaaacgga acttcagcgg cgccatcata cccgtctgat gattcggagt
     1261 agtcgaaaca tgggcggccg tagcctttgc cgggaagaaa agatttgtgc tgtattggat
     1321 gaatatacgg tcaagcgaat tggtgttatc gctagcccag aactcgtcat gatatttcaa
     1381 tgcaccgaag tcgagacggc cgccacccga agaacacaac tgaataagaa catccgggtg
     1441 ttttgcacga atccgttcgt aaacactgta caagcccttt gtatagtcaa tccagaaatg
     1501 agtctgattt tctttggaca gatattcgga accgaaatta tccacgtgac ggtttgcatc
     1561 ccattttata taagagatat caggagacaa agcgatcact tcatcaaacg tctttacaac
     1621 aaagtcctgt acctccggat tactcaaatc gagtaaccac tggttacgca tcgggattat
     1681 atcacgttta ccgctcttga cgatccattc cggatgcttc tctgccagtt cactcttggg
     1741 acttaccatt tcaggctcaa tccagatacc gaacttcaat cctttactta ccgcatgctt
     1801 cgccagataa tcgattccgc gtggcagttt tttcctgttc acctgccaat cgcccaaacc
     1861 aaccttatcc gaattgcggg gatatttatt tccgaaccat ccgtcatcga gtacgaacat
     1921 ttcaacgcca aaagcagcag cgtcatcgat catatccgta atcgtttttt cattaaaatc
     1981 gaaataagcg ccttcccagc tattcaggac gataggcaat tcctgatctc catgggccaa
     2041 tgcatagtta cgcgaccagt catggaggtt tctcgatacc tgtcccttac cggtagaact
     2101 gtatgtccag accatttccg gagtctgcaa cgttttaccc ggttccagat tataagtaga
     2161 ggcaaaatca ttcatcccgc tcatgacatg cagcaaaccg cattcgtcta tctcaaagga
     2221 agacagatag ttacctaacc aggccaggga gccggcatac acttcgccca tgtcttcatt
     2281 ggcagggcca ttcagggaaa gcaggaaaga agagttttca gactgggtag tacgtatccc
     2341 cttcttggat tccacccgtt tcacacccgg tgtcagttgt tcttctacca gttgcatttc
     2401 ggaagcccag gccccgtgga aatgggtcag ataataagaa tctgcatgaa ggggaagata
     2461 agcggaggca atattctcga cagccagctt gtttttctcc tgatgggata tggagactga
     2521 ctggcagatt acattttctt tctgataagc cgtgaagttc aggttaacga aaaccggata
     2581 caaaggatct ttcaattgta tcactgtttc tattctatta ttatctatat tctttacctg
     2641 atgagctgca tatattaatt cggttgtctg aacgccgtcg tcatgggtca gtttcaatgc
     2701 cggattcagg aagaaacgtc ctccgtaagc cggatagatt accggagcat aaccgattcc
     2761 gttatccggt tgttctttat acttcttatg aaggaaaggg gaaacgtcct ggaatttatc
     2821 gccaaaatag ttatacacta ctttcttatc cggagagatc gaaaagacca tactcagatc
     2881 gtttgtagag acggtaatta tccccgtatc tttatcctgt gaggaaacgg ttacgcaccc
     2941 cagcagcagg gcaacagtta acaatagtgc tttcatgtct atcaaattta ttttacttat
     3001 tcaaggttga tggtgcaaac taaatcaata aacaatagca caaaaagcac gaactcgcca
     3061 attatttgta attatgcgct taattcatag aggtttaata aaaatgcaac atttacgtca
     3121 ttttttgacg catctgttac aaagggatga tcgatcactg atccttttct cgagaggcta
     3181 tcaggtcagc tagccttctg gtcaaatagg ttaatatata agtatccaca ttatcgaccg
     3241 tcaaaggcgg gtctgccgtc cagaaatttt gttctcctgt ttcatccaat gcccttttag
     3301 ctttatataa cagatcatat tcttgcaaca gaggcagcct ggaagattga tagagactgg
     3361 ccagacattg tataatctcc aaaacagacc ttcgttcttc ctgttcttcc agtataagga
     3421 atatcaaata attatttaat acagtctctt tagagaaata caaattaaac tccaggaaaa
     3481 tcacctccac tcttttcttc aattcttttt gagggagagt cagagatgct tgttcagcca
     3541 taattttcat attatcactc acaaatccgg catcaagcat caggttagcc caattcagaa
     3601 acctttggtc tattttttga ccgaaaataa acagtgcctg tatttccagt gtttcaggaa
     3661 ctttcaaagt tatatcctgc gccttgaaga gtgttccggg gcgaagggaa aaacgtttca
     3721 tcacataaat caactgatca atatcttcac gcaaatccag tttctgaaac attttaaacg
     3781 acattcccaa acatgccata tctggctcaa tcacgaaaag agacttgcct ttcagataag
     3841 caattatatc ttcggcatgt atcagctcct tttctatcgg tacatagaaa ggaacggata
     3901 tgaaaatcaa agacacatta cgccctttgg gattcatttg ccgcaaaact tccgttctaa
     3961 acagaaaatg gtccttcctg cattccaact gcaaccgtcc ggtttgattg ataggaccat
     4021 cccattcgta acgcatcaaa accgtctgca ttagttccct caactttttg ggttttctgt
     4081 aattgttgat gaaagtcaat aacaatgtca aaggcaaaat aaagaggaaa gggataaaag
     4141 aaacagccaa taataatccg ctatctatat ttccggataa aagacctgtt attaataaaa
     4201 tgattacaca aggtatacac aacaaaagaa ctaatgacaa agaataaacc aaccaacctt
     4261 taatggtttt gaattcaagc aaattcaatt catccatatt acctttcaaa agagaaagat
     4321 attttataat atcagcaagt gatattttat cttcatgcag tcctatatat tccatagctt
     4381 gcaaagataa cacctcaaaa tcaaagattc atacaaaatg atgagaaaag aaccccctat
     4441 aaacaattaa agcctgtctc acgacaagcc ctaaccaact ttgttaacct taaatctaat
     4501 actattatga aaaaaccaca gtacaaagat aagcctgaaa caagcgtttg tcaagtcttt
     4561 tacagacaat atatgttaag cctttcgggc attgtagcta aaaattgttt ccgaacacaa
     4621 aactttatac aatacagaca aaaactgcta attttaacag ttaaaacagc caaatctata
     4681 gagaaagacg ttctttaagc aacttgtatc cggtcaggct ggcacgcaga cagacacctg
     4741 ttttaagacg aacctggtaa ctttccttgc cgaacagttc cacacgcatg atctgttcgc
     4801 tattaacgat acaggaacgg tgaatacgga taaacaggtt tgccggcaga tgcgattcaa
     4861 aatatttcat tgtctgatct tttatatact gtccgtcggt cgtgaagagt gccacatagt
     4921 caccgctggc ctggatataa agtaactcct ccaggtggat cagatggata cggctgccat
     4981 ccttcacaga gatgcgatcc agtattgctt cctcttccgg tgacgatacg cctgtttccg
     5041 ccggagcatt ttcttctttt ctctgttcct cctgtatctc catctgcaac tccttccaac
     5101 ggatataata ccactgggcc aaaataatcc atcccagcaa acccaacaaa atacggaacg
     5161 gaatggtaga tgcaaaccaa tccatcctat ccggataaac cagcgccccg gccatatatc
     5221 ctccggtaac ggatatgata aggacgccaa cagccaatgc aatctgggcc tgtaatggcc
     5281 gcaatatgcc tgttacatac cagaacagga aaccggagac acagaatata ccgaccgaaa
     5341 ccagactatc caaccatgcg acaagccatc ccgtatgtcc gtaataatag aggagcaagg
     5401 cgcttatgct gcaactgacc acagccaaag ccacaccagc cattctacac aggacagaat
     5461 ttataaacgg atgtgtctgc ataatcaact cttaaattca atgccaccga acataacaat
     5521 tccccgtaca accagtatat gttctttatc catttccata gaggcattaa aacgtttatc
     5581 ctcgcatgcc cccatgatcg gactgccatg aaaattgacc gcccaatccc caggaagata
     5641 gatttccaca ccggcaaact tacaatcgat atcaatatag gttttagcac tatccagctt
     5701 cgttttccgc aaatccagga ccgttccccc aaacacagtc ctaatcctgg ctcctttaaa
     5761 taccggatct aaaataattt gttccacata gccaaatgta ttatccgatt ccacatatcc
     5821 gtccgtatta ataaaatcac tttttacttt accggcaacg gcatttcccc ggatatcttc
     5881 tccaccggta tcctctctcc ggctattgta atgataggag ttctttttac gcggttcgaa
     5941 gatcagcatt aaaccgacaa tgacaaaagc agccggccaa tagacctgca accaatcgct
     6001 atccatccac cccagtcgtg gcagtaaaaa tgccgcacca accaaaaagg taatcaaacc
     6061 gcctatataa tgtctccggg aaatactccc tatacctata tacattacaa gcatctgcca
     6121 ggatacaatg atatgaaaaa gatcatccgt gatcatgcct gtgttcctca tgatccatac
     6181 gacccccact acaataaacg ggatggccca aaataagttt ttcctaagat tcatacgata
     6241 tacagtttaa ttgtttgaga gcaaaagtat gctcctgtca gccttccggc aatagaaata
     6301 cgtcctatta cagtcaaata tcggtgaatt gccgaatatt accgataaaa aagggagtta
     6361 tttttcagag aatgccatat ttaaaagaaa aaaggcttgc atttccgaat gcaaacccct
     6421 ataaacaatt aaagcctgtc tcacgacaag ccctaaccaa ctttgttaac cttaaatcta
     6481 atactattat gaaaaaacca cgatgcaaat atactgctta atccaaacct gtcaagaggt
     6541 tttatgctaa atggtgtttc atacactata agaaaagcta acaaggttca atatgtttgt
     6601 tttttgcttc caaagtgtta aaataaacac tttttattcc tatttcttct ttaatatacg
     6661 ttgtgcacag tcggacaata ccacgatcgc tccggctatg attgccgtat cttttattac
     6721 cagccgacct gctccggtca gtaaggggaa accatgttct ccgcttccca aatcgggcac
     6781 ccacacttca ggtgttgtca ccaggaatga aagcgtaccc aatgtcatta tgatcgccag
     6841 tccggaacct atcaagccaa ttttcggaga aaagataccc aggaaagtca ggataccgat
     6901 cgccatgatc ataatgccta gtccatgtga aaaaatatag gtattgtttt ctacatgcca
     6961 ctgatgcttg gcttcattga attcaccttc tttcaactta tattctttgt attccggtgc
     7021 actctttgca tagaaaaagc tcataaacgg actgtttgcc acaaaaggaa cgatcccttc
     7081 cgcttcataa ttatagaatt tcagcccgcc gatccatacg aatataatca ggatagctac
     7141 gcggatcagg ttaataccca gtttctgtga agaagctgca atgttcagaa atgtgtcgaa
     7201 taaatctttt aatttagtag tcatgtcttt ctttgtttat cagtttaact tatgatgcaa
     7261 agatccgaca tttttcccct atgggaaatg gcaattctac cggataattt gacaattatt
     7321 cccttaaaca caataaagcc ggttaacaga ggtatatttc ccgtcaaccg gctttataaa
     7381 tgatccgtta tcggaactat tttaattacg aactcccagc tccaccagtt tctgttcgtc
     7441 caaggcatat ttgcgttcga tactctgcaa aagctcttca ctgatattca gaggacggtt
     7501 cagcttcttc atctcccggt atcctttata gacctgcgtg atcatcttgc ggggattgaa
     7561 aacaagcgat gaagtgatcc aacacccatg cgtacaccag cagttagcct tgtcaccatg
     7621 accgatagcg gcaatctctt gtttcatggc atcgctctcc ataatctttg cgatattgca
     7681 gtcataatcc ttgacattac cgagcggttc gcgaagttca caggcacgga aacgaccgtc
     7741 atagtctatt accagtgttg tttcgccggc cgtacaatcc ataccccagg gtgtcggatg
     7801 atcgatattg gtcgcacgta cattatataa tgtacgtatg aaacccaggt agaagaaacg
     7861 ggcgataggt tttctgaacc caccggtttc ctccgccata cgctccccat atacattata
     7921 aataggaaca accttatcct gcaaggcgcg tagagtaggc tcggtaagaa ccttcactcc
     7981 gtcgtcgcgg gtcataccgc gtgcagcttc aataatatga ttggaaagat ggaaacgtcc
     8041 cagcatccat atcatcagat cctcgacctc attctcgtta tatttggtga ttacggtggc
     8101 caggtttttc aacaccctgc cgtcgtcagc aaagtttttt tcaatcagct tcagtgtccc
     8161 catcgctttg tagaaattgc cgggaacgcc gcgctgtata tcatgcgtat caccgaaacc
     8221 gtccaaagaa aggctcaggt tgatattcag ttccggacaa ttctggcgga tctgttttac
     8281 ccaggcgacg atccggtcag gcttcaatcc gttggtaggg atattcacgt cctttatctc
     8341 gttattcttg tagaacatct ctataatttc aggtaactcc tcacgcagtg tcggttcacc
     8401 gccggatacc cacaaacggt tgaactgccc ggctgtttcg gagattgtct tgatttcttc
     8461 aaaagtcagg tctttctcct ttttatccat gtcttctgca tagaaacaca ttttacattt
     8521 agcattacac cgtcctgtga caaacaggaa aacagattct aattttctgt ttgtgctcat
     8581 tgtcctgaaa gagctctttg ttcttttcgt actcattgtt attatcgatt agatttctct
     8641 attagtatta gctcccatat cttatttagc agatagacaa atatatacca tcccaacaaa
     8701 tctatcagca agacttgaaa acattcgcaa atttcaacta ttatacagca caaaacaatc
     8761 tccatttgtg ggattcgatg ttctatattt aagattatcg actaacttgt ctcaaaaaaa
     8821 ctatctttgt acattcaatt aagtgtatat aaaagtatgg aagacaatat tcctaaattc
     8881 gacctccccg tagattttat tgtaggaaac agtattacag gtgaaatact gaaccagtac
     8941 ggacgtttcc cgtgcaagat caaggctggc atattcgtgc tttgcgtaca agggacagtc
     9001 cacgcgactg taaacttaac tgagtttacc atccggaaga acgactttat caccttaccc
     9061 ccgggttgct tcattcagat acatgaggtt tccgatgatg taaaactgtg ttttgcaggc
     9121 ttttcttccg tattcgtcag ccatatcaat tatataaaga cgattacgaa ctatctgcct
     9181 gtcatattcg acagtccgat catgcctctg ccggaacata tatccttact ctaccaacag
     9241 gctttcgact tgctgatcaa tgcttattcc atgcctaaaa ccatcgagaa caaggagatt
     9301 atcaaggcaa tctttactat cttcatgcaa ggggttattg aattatacag gaatcatacg
     9361 ccatatagca atgctcccat gacgcgtaac atggaaatat gccgggagtt cgtacaactg
     9421 gcgatggaaa actacacgaa agagcatagc gtgtcttatt acgccaaaag gctcaacatc
     9481 accttgcagc atttctgtta tgtgataaaa aaggtcagcg gacggactgc attggatatc
     9541 ctgagcaata tcatcattat ggatgccaaa gcgcagctta aatcgaccga tatgccggtc
     9601 aagaaaattg cattcgccct gggtttcgac aacctttcgt tcttcaacaa atatttccgg
     9661 caacatgtag gaatgacccc gcaggaatac agggagagct aaaaaaaggg atatgccgga
     9721 cgcaaacccc tataaacaat taaagcctgt ctcacgacaa gccctaacca actttgttaa
     9781 ccttaaatct aatactatta tgaaaaaacc acagtacaaa gatacaggta ttctccaact
     9841 tgtcaatagt taaaatgcta attagtgttg tatagcatat aagaaacact aacaacattc
     9901 aagatattta tctatgactt cagaaatgtt aaaatagggg caaaaaagaa gaggcgctgc
     9961 cataagcaac gcctctccgg acatacatat ataatgtata ttagtcttgc aatttagcac
    10021 aaatgaactc gcggttcaaa cgagcgatgt tgctgacaga gatgttcttc ggacattcca
    10081 tttcgcaagc acgcgtgttg gtacagttac cgaagcccag ttcgtccatc ttggcaacca
    10141 ttgctttcgc acgacgagca gcttctacct taccctgagg caacagagcc aactggctaa
    10201 cctttgcaga aacgaacaac atagccgaac cgttcttaca agcagcagca caagcaccgc
    10261 aaccgataca tgcagcagca tccatagcca tttcagcatc tgcacgagga atagcgattg
    10321 aattggcatc aggtacacca cctgtgttca ctgatacgaa accacctgcc tggataattt
    10381 tatcgtaagc ataacggtct accatcaagt cgcggattac cgggaaaccg gcagaacgcc
    10441 acggttcgat tgtaatagtt tcgccatcat tgaagcgacg catataaagc tggcaagtag
    10501 ttgcgccggt tgcaggtccg tgcggatgtc cgtttacata caaagaacac ataccgcaga
    10561 taccttcacg acagtcgtga tcgaatacga tcggctcttt accttcactg accaaacgtt
    10621 cattcaaaat gtctaacatt tccaggaaag aaacactctg attgattttg tctatttggt
    10681 aagtctcaaa ttgtccttta tctttcggac ttttctgacg ccaaacttta agtgttactt
    10741 ttatatcttt atccatgatt ctaatttttg tgattgatga ttattacttc ttgtagttac
    10801 gtgtttgagg aacaacgaac tgatagttca aatcttcctt cagcataacc ggatctttgt
    10861 cttcaccctg gtattcccaa caagatacgt acatgaactt atcgtcatga cgcagggctt
    10921 cgccttcctc ggtctggtgc tctgtacgga agtgtcctcc acaagattcg gcacggtcca
    10981 atgcatcgtg tgccatcaat gtaccaatct caataaagtc agccaaacgc aatgccttat
    11041 ccaactctac gttcaggtta tcggcttcac ccggaatata tacattactc cagaactctt
    11101 tcttcagctc tttcaacatc tggatcgctt cctgcaaacc ttttgcatca cgtgccatac
    11161 ctacatgttc ccacatgata tgacccagtt tcttatggat agaatctacc gactctttac
    11221 ccttgatact catcaatttc ttgatgcggt ctttgatccc cttttcagct tctgcaaact
    11281 caggcaggtc ggtgctgaaa cgtggaacct ggatctggtc tgacagatag ttctgaattg
    11341 tataaggcaa tacaaagtag ccatcggcca atccctgcat caacgcagaa gcacccagac
    11401 ggttagctcc gtggtcagag aagttagctt caccgatagc gaacagaccc ggaatagaag
    11461 tcatcaattc atagtcaacc cacagaccac ccatcgagta gtgcaatgca ggataaatca
    11521 tcatcggagt ttcgtatgga tcgtcgttgg taatttcttc gtacatgtcg aacaagttac
    11581 catatttagc ttttacaaca tctttaccca gacggttgat ggcgtcggag aagtcgagga
    11641 acacggccag acctgtgttg ttcacaccga agccggcgtc gcaacgttct ttagcggcac
    11701 gtgaagccac gtcacgcgga accaggttac cgaatgccgg ataacggcgt tccagatagt
    11761 agtcgcggtc tgcttcagga atgtctttcc ctttcttagt tccggcctgt aatgcttttg
    11821 catcttccag tttcttcgga acccagatac gaccgtcgtt acgcaatgat tcagacatca
    11881 aagtcagctt agactggtag tcacctttca ccggtacaca agtcgggtgg atctgcacca
    11941 tacaagggtt agcgaagtaa gcacctttct tgtagcactg ccatgcagca gaaccgttgg
    12001 aagccattgc gttagtagac aggaagaaag tatttacata accacctgtt gccaccacta
    12061 ctgcgtgagc agaaaaacgt tcgatctgac ctgtgatcag gttacgtgcg atgataccgc
    12121 gggcacggcc atccaccttc acaacgtcca gcatttcgtg gcgggtatac atctttactt
    12181 tgttcaaacc gatcatacgg ctcaaagcag agtaagcacc cagcaacaac tgctgtccgg
    12241 tctgaccgcg ggcatagaac gtacgggata cctgagcacc accgaatgaa cggttatcca
    12301 gcagaccacc gtattcgcga gcgaaaggaa caccctgtgc tacgcactgg tcgataatag
    12361 agttggaaac ttcagccaga cgataaacgt ttgcttcgcg ggcacgatag tcaccacctt
    12421 tgattgtatc gtagaacaga cggtaaacag agtcaccatc attctgataa ttctttgcag
    12481 cattgatacc accctgtgcg gcgattgagt gtgcgcgacg gggagaatcc tggatacaga
    12541 agttcaatac gttgaatccc atttctgcca gagaggcagc agcagaagca ccggccagac
    12601 cagtaccaac tacaatcacg tccagacgac gtttgtttgc ggggttcacc agtttctgat
    12661 gatctttata atttttccac ttctcagcca acgggccctg agggatttta gaatctattt
    12721 gagtcataat gatttatttt caatattgtt acaccttaaa ttaatgtcct gcacaaacag
    12781 ctacatagtc accacctaca ccattcaggt agaaaacgat agtaatgata gcaaacacta
    12841 cgcaaataac ggttgctaca atcttggaaa tgcagatcca acggttcatc cagatcgtgt
    12901 tactccaacc gatagtctga atagcgctcc agaacccgtg agtcaggtgg aaccacaaag
    12961 ctacgtacca taccagatac agcactgtat tcaggatatt accctggaaa tagtagttga
    13021 taaacgctgc accgtcctga ggagatacgg ttgttgttcc gtcgcaaagt gttaccatgt
    13081 gattgcctag gagttcggcg aacatcatct tataccagaa ctggctgaag tgcaacacca
    13141 tgaacaggat aatgataata cccagtacca gcatgttctg agatgcccat tccacacctt
    13201 tcggacgagc gttaattgca taacggtcgt taccgcgagc cttacggttt tgcagtgtaa
    13261 ggagaacagc atacacaaag tgaatcacaa cgcctgctgc cagcaccaat gttgctgcca
    13321 cggcatacca atttgctccc aacaatgaac aaatcatgtt ataggcttct cccgagaaag
    13381 cagccgccac attcattgac aagtggaaca ataagaacaa aacaagaaaa aggcctgata
    13441 cactcattat cagcttcttc ccgatagaag aattaagtaa ccacataaga taataattta
    13501 agttatttaa ttgtttttag aaattcatat caatatactc aattatcagg caaaggtatg
    13561 ctaaatacac gtatcacgca aacgattaaa gaaatatttc gccaatcaaa cctatacatt
    13621 tcaggaggga caaacggtaa atcctattca ataaataaat taacgaaaat gtaaccagta
    13681 ctaaccggca tttttatatc ttcgtggcat aatcagggga tcgtatgtta caacgtaaaa
    13741 tgctgagctt cttatttatg atgattttta taccgtctgt tcgtgctcag tggaaagata
    13801 gtacgagatt cataaataaa gaacatgaat ttgaaaccac ttacaacaaa atatcagaga
    13861 ataaggtata ccagatgctg cgtgtccctg ttcctctttt cgccatttca gccataacat
    13921 atgggcaggg cgataaattc cggacattgc gcaatacgca tacgcccaac ttccattaca
    13981 gatacgatga ttttctgcaa tatactccgt tgcttgctgt ttacgggatg aagctcggcg
    14041 gtgtggaaag tcgtagttca tggccccgga tgatcgtatc gaacgctttt tcggcaacga
    14101 tcatggccgc taccgtcaac agcatgaaat atacgatcaa acgcgaacgc cccgacggct
    14161 caaagaacaa ctcattccct tcgggacaca cggcaaccgc tttcatggct gctaccatca
    14221 tgcaccggga atatggtctg acccgcagcc cgttatatag tatcggggga tatacagtcg
    14281 ccacagccac cgctttcagc cggcaactga acaaccgcca ctggctgagc gacgtactgg
    14341 ccggggccgg tatcggcatc ttatccacag agttagggta ttttctggca gacctgatct
    14401 tcaaggacaa aggcttgaat ctccctgaca agctcaggga gtctgccccc aaaggagggc
    14461 gcccttcttt cctggagttc gccgtaggat acagtatcat caacggaagt atcgaggtag
    14521 gtaaaaatat acgcctgagc tcgccgggag caaccaatgt cagcgtaaaa ggcggttact
    14581 tcttcaatcc ttatttcggt atcggcggcg aaataacagc gctggcaagc ccgatggcat
    14641 tcgacatgtc gctttataca ggaacaaccc cttcaaccaa atatgacatc acccgcatcc
    14701 atgccgatcc gaccggtgtt tttactttta cggcagggcc ttatttctcg ttacctgtag
    14761 ccagtaaatt gcttttagga acaaagttcc aggccggata ttcctatctg gtgaaaaatg
    14821 aagtggaaat ggacttacag gaaaagcacc ccccatacgg aaccataaat aatattgctt
    14881 ttatgaaagg caacggtagc agcaactatg ttttacgcac aggcatttca gcgaccggga
    14941 tcgtcagccg caacctgggt atccgtatgt tcgtagatta cgattatacg ttcctgaaag
    15001 caccttacga aatcttaacc agcctcagag acagccaacc agtctacggc gagagccatt
    15061 taagcaagca caaaatacac tattttacaa taggggcaac cgtaacggcg ctgttctggt
    15121 aattatcagt cagcagcagg aaccagccgg actttgatat cgctctcctg cccgctttcc
    15181 agacttacat cgaaaacgat acggcaggtt ccctcattgg aagcatcata gctattcttc
    15241 gatacattat caaggacgga cacagaagtt acggatggac tatcaacgat cagttgcata
    15301 catttgccgt cttttgtcag ttccaccata tgactgtcca atacacgggg aatggccccg
    15361 gttacaatcg tccatctgac agttgccggc tgactgccag cttttacacg atcaatcacc
    15421 gacagatatt tttcattgat cagagcaact tcacggacgg cattttccaa ttctccgccg
    15481 aacaagtccg tcatattcag agaagctccg agtttatgcg cttccgaata gatatttgtc
    15541 acaggtacaa aaccgtttac atcatggtat ttaccgttta cagtcagtgt attatgcgcc
    15601 aggttattat aacggaacac attccagcgc tgcccgttct gcgacatatt ccataaatct
    15661 acattttcct tttccagcga ataatattcc tgcatcccca ggtcctgcac ccagcgaaca
    15721 cccgaagcat cgaacacaaa cgatccggca tccatatggg catggctggt cgaagccgtt
    15781 cctcctttta ttcccagata gaaaccttct ccattctccc aacccgtacg gaccagcacg
    15841 acaggcgtct gtccgttagc cgcccacaat ttcatagcag gaggcaccag ttcattcatt
    15901 ttatattgtg aaccataaat cggaatcaac ggaaggaaac ggctctcctc atccgaaaaa
    15961 gacaactccg cccgactcaa catatccttt tcattccaaa gcagtgtagg gtcttgcagc
    16021 ttgtcggcaa accagtacat agccggcaaa gcaaagacac tctcacggga atcgctgaag
    16081 ttaaagcatt taccggtcgt tccggtcata aactgcataa aacgggcaga agccagaaaa
    16141 ccttcagccg aagagagacc gccgtcagtc cccaaggcgg attccaacgc ggcattcaaa
    16201 agaacctgga aggtagtccc gtatccccaa taattatatc cttcgggata agcgccatcg
    16261 ggaccatagc ccttcaaagt caagccgact gtagataaag cacgttcaat gatttcacgg
    16321 gcctcttccg gatgatcttc taaaacggca agtgcaccgt aaaccagtcc ggcattacag
    16381 acctggttcc agttattggt cgctctcaga aaccagttat atcttttatc cctcgacggg
    16441 gcaaaacctt tattcagaat cgcctcctgc accagcctcc gggcatccgg agataaccga
    16501 tcgaacaacc agtcataacc gattgcaacc gccatagtca tttcgcccgt atccagaaaa
    16561 tgggacgggt tccaatcggt aaacgaacac acggcaatca tttcctgctc tgcccgcaaa
    16621 cgatacttat cctctcctgt catccggtaa gcatatgaaa gatagaagat acgccgcaag
    16681 gcttcacgcg atacggccag caaccgtttc ccttcttttt tatatgccag cacaggcgtc
    16741 gtgatcagat cgtcgcattg cccaagtaga tagttatgca accggagcat ctccggatta
    16801 agagccagat cggatttaat cttttgctcc tctcctttct ttaccagcaa ccggggatga
    16861 gaagggtaag aatcaaagcg tattccctgt gaataccccg aaacgaacag ggaaaagcaa
    16921 aacacaacaa gcaggatagt tttattcata caggtattat atttaattgg agttacaaac
    16981 ttacataaaa attgagattt ataagcgcgt ctaataaaaa taaagaccac tccctgctgt
    17041 tattccaccg ac
//
