LOCUS       c00373_gnlPro..        13594 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EFLHGBCO_373.
ACCESSION   c00373_gnlPro..
VERSION     c00373_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 02:50:51
            Original ID  :: gnl|Prokka|EFLHGBCO_373
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13594
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13594
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6064:12504]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6065..12504
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
     cand_cluster    1..13594
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /kind="single"
                     /product="OD_unknown"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13594
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_unknown"
                     /region_number="1"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /tool="gutsmash"
     CDS             complement(251..1981)
                     /locus_tag="ctg373_1"
                     /transl_table=11
                     /translation="MRRVYSIALLLLVALGLSATTKEVKLKLLETSDIHGNFFPYNFIE
                     QREWGGSLARVYSFVQEERRAYGDNLLLLDNGDILQGQPSAYYYNFMDTVSTHIASAMM
                     NYMGYNAGNMGNHDVEAGHAVFDRWIKQCDFPILGANIIRTSDRETYLKPYEVFERDGV
                     KIVVLGMITPAIPVWLPETLWQGLYFADMEETARKWMKIIQEKEKPDVVVGIFHAGNEA
                     RTMSGQYREDASMEVAQRIPGFDVVIMGHDHRRYCGKVANIEGDSVLLINPASNGRVVG
                     SVDVVLKMEHGKVLDKQVSGVLTDVDKLEPSKEFMEKFAPQYKAVNDFVSEKVGTFTES
                     IATRPAYFGPSAFIDFIHSLQLELTGADVSFAAPLSFDAKIDKGDITISDMFSLYKYEN
                     MLYTMNLTGAEIKGFLEESYAMWTNRMKSPDDHVLLLKERKKGQENYVSFVNFSFNFDS
                     AAGIIYTVDVTKPKGEKITILKMADGKPFDENKTYKVALNSYRGNGGGELLTKGAGIPQ
                     DELKSRIIHSTDKDLRYYMIQYIKEKGVLSPQPLNQWQMIPQDWTRPAAERDCKFLFGE
                     "
     CDS             complement(2000..4426)
                     /locus_tag="ctg373_2"
                     /transl_table=11
                     /translation="MKTYLFLLLFVFQAFSLSSQISLKGYNQEKIDPSLFEGRWKARWI
                     SYPGEAPNVYGVYHFRKSFDLEVVPSRFIVHVSADNRYKLYVNGKLVSLGPARGDIYNW
                     SFETVDLAPYLRKGKNTLASVVWNYAERKPVAQISYDQTGFILQGNTGHEAVVNTDTTW
                     VCLRNKAYAPWTEWQVLGYYVAGPGEELEASAYPWGWEQPDYDDRKWEKAVRGMEGATK
                     GSRDYPGRLLVPSPIPPMDSRIERLAKLRRSEGIECPQGFPYWPKALTIPANTEVRLLL
                     DNDYLTTGYFSLAFSKGKEAEIHIGYSEALYKQEEESTTKSYALNGKGHRDELTDKQFI
                     GYGDKILADGGDNRLFTSLWWRTWRYVELKVKTASEPLVIEDMYGTFSAYPFRNETAFS
                     APGHEELGRMLEIGWRTARLCANETYMDCPYYEQLQYFGDTRIQAMISMYNTSDPYMVK
                     NALEQGRQSMVAEGITMSRYPSSVHQFISSFSLWWICMGHDYWMYRGDEAYMKTLLPAY
                     RQVLSWYEQWLKPDYSLSYVPHWFFVDWAAGFDYGEPIREKEGNSALQDLMYIMTLEFA
                     AEMEQAIGLPAMADHYRKIATEMRKTIRPKYWDAARNLFADTQDHRSYSQHVNALAILT
                     GVTKGEEAVKVMNQTLADTSLIQCTIYFRYYLNQALKASGLGDQFLDNLQIWRDQMALG
                     LTTWAEMPEPSRSDCHAWGASPNIEFYRILLGIDSDAPGFRKIRIAPSLGKLKEVSGTI
                     PHPLGSVTAAYKLNERGEGTARLVLPEGTTGIFIWDGKEIPLKPGEQVISLSSRH"
     CDS             complement(4548..5336)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg373_3"
                     /sec_met_domain="Fer4_7 (E-value: 4.5e-11, bitscore: 32.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.7e-11, bitscore: 31.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.6e-06, bitscore: 15.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYSNIHLIYFSPTHTSAKIAYAIAEGMGATSMSESDVTCESLDM
                     EEYIDDELTIIAAPVYGGRVAETAMERFRMFRSAHHAPVVPVVLYGNRDYEDALKELCD
                     LVSEQGFVPVAAGAFIGEHSFSRKGMPIAEGRPDESDLKQATEFGKKIIEELEKVSCVE
                     CLSALEVKGNFPYRVKGPSTPQAPVTDNDLCTQCEYCVDVCPTHAISLADEGMYSDPNL
                     CIKCCACVKECPEGARTFDTPYTAMLHKNFSARREPEIFF"
     CDS             complement(5342..5917)
                     /locus_tag="ctg373_4"
                     /transl_table=11
                     /translation="MRFDENFNVSLSLNPKREMIKVMKKYLLVSLLALLAFVGKAQEDN
                     SDIVKVGDTMPSFTIVSDNGSKLQSASLKGKVILVNFFATWCPPCQKELAAVQQTLWPK
                     YKNNKDFVLLVIGREHSDADLQKYNEKKGFDFPLYPDKDRAIFGAFAKNLIPRGYLVGK
                     DGKIIYTSKGYTDEEFAELMTKIEGALK"
     CDS             complement(6065..6646)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg373_5"
                     /sec_met_domain="POR (E-value: 5.3e-44, bitscore: 139.9,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTDIILSGVGGQGILSIAAVIGEAALKEGLYMKQAEVHGMSQRG
                     GDVQSNLRLSDEPIASDLIPKGHADLIISLEPMESLRYLPYLKKEGWLVTNSRPFVNIP
                     NYPEIEKVNAELDRLPHKVVLDVEEIAKEAGSVRAANIVMLGAAAPFIGIEYDKIEAGI
                     RQIFGRKGEDIVNMNLKALKAGYDLAQSLR"
     CDS             complement(6643..8244)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg373_6"
                     /sec_met_domain="POR_N (E-value: 1.4e-14, bitscore: 43.9,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-18, bitscore:
                     56.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHLFLGDEAIAQAAIDAGISGVYAYPGTPSTEITEYIQGSPVT
                     KERGIHCRWSTNEKTAMEAALGMCYAGKRALCCMKHVGLNVAADCFMNAAMSGINGGMI
                     ILTADDPSMHSSQNEQDNRVYGNFAMIPMFEPSSQQEAYDMVYHGFELSEKLGYPILLR
                     VTTRMAHSRAGVVTSPLKPENRMNCPEDGRQRFILLPALARKRFKSLLASQEAFTEASE
                     NSAYNKYFDAPNKDLGIITTGIAFNYLSENYPDGFEHPVLKISQYPLPRKQVEKIVGEC
                     KEILVLEEGYPVVEEQLKGFLAKGVTVHGRLDGTLQRDGELTPDAVGKALGKEIQSYYA
                     IPEVVEQRPPALCQGCGHRDMYEALNEVIAEYNGTAKVFGDIGCYTLGALPPFRAIDSC
                     IDMGASITMAKGASDAGVFPAISVIGDSTFTHSGMTGLLDCVNENTNITIVISDNETTA
                     MTGGQDSAGTGRLESICAGIGVDPAHIRVMVPLKKNFEEMKSIIREEIEYKGVSVLIPR
                     RECIQTLTRKKKASKK"
     CDS             complement(8349..9398)
                     /locus_tag="ctg373_7"
                     /transl_table=11
                     /translation="MDLNKQILSRRPIIIALIAILVVLIGGGGFWVYRLAWAPNFKPDK
                     TVYVYIDDKKDFDDLCRQLSDSANCLRIGSFKQLSGLLKYPASMRTGRYAVKPGMSNLT
                     LLNDLRRGHQVATRVTFNNIRFKEDLAERISDQLMFGKENLLRLLNDSVYCDSLGFTPE
                     TIHALFIPNTYEIYWNISADKFIRRMKREYDAFWTPERLKKAEEIGLTPVEVSILASIV
                     EEETAASDEYPIVAGLYINRLRAGIPLQADPTVKFAVGDFSLQRILFEHLEIDSPYNTY
                     KYAGLPPGPLRIPTIKGLNSVLNHTKHKYLYMCAKEDFSGRHNFAVTLAEHNRNANRYR
                     AELNRRRIR"
     CDS             9764..10381
                     /locus_tag="ctg373_8"
                     /transl_table=11
                     /translation="MTIAFIRTYNNKQNSEVQEAVIREFAESQKIEIGKWAKEVGNSPR
                     ANRRLESIVKSLSPGDEILVSDISRVSRKMIEIIHIILLCIERKVTLRSVSDGYVFEDN
                     IDSKTLAFTFGLVSEIERKLVSIRTKEALALIRSKGVVLGRPKGSQQMGRLEPYKEQIE
                     KDLKDPSLTYAQIAEKYNVSLSSFKRFLKEYLPDKKKKKTKK"
     CDS             complement(10444..12504)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: Succ_CoA_lig"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: CoA_binding_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg373_9"
                     /sec_met_domain="Succ_CoA_lig (E-value: 4.8e-37, bitscore:
                     116.4, seeds: 149, tool: rule-based-clusters)"
                     /sec_met_domain="CoA_binding_2 (E-value: 4.2e-22, bitscore:
                     68.5, seeds: 225, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINRELINPQSIVVVGGSNNVHKPGGRIVRNLLDGKYKGELCVVN
                     AKETDVQGVKSYPSVHDIPETELAIISIPSKSCPEVMEVLARQKGVKAFIVISAGFGEE
                     THEGGILEQQMLDVVNEAGASLIGPNCIGLMNMNYHGVFTQPIPEFHPDGVDFISSSGG
                     TALFIIESALTKGLRFSSVWSVGNSKQNGVEDILEYMDRNFDPVLDSKIKMLYIEQIKQ
                     PDKLLYHASSLIRKGCKIAAIKAGSTESGKRAASSHTGAIASSDSAVEALFRKAGIVRC
                     FSREELTTVASIFTLKDVKGKNCAIVTHAGGPAVMLADALSKGRLNVPSLEGPIADELK
                     SKLYPGAAVGNPIDIIGTGTPEHLATAIDFCENRFDNVDLMMVIFGSPGLVKLYDTYEV
                     LHKKMEECKKPIFPILPSIVTAGPEVKSFVKKGHVNFSDEVTLGTALSRVINTPKPMST
                     DIQLYGVDVPEVRRIIDRLPGSGYLNPEEVRTLLRAANIPLVEEYASDDRDALLAFAKK
                     VKYPVVAKVVGPVHKSDIGGVALNIRGEEHLLFEYERMMRLPGVTGIMVQPMLKGQELF
                     LGAKYEDRFGHVVLCGLGGIFVEVLKDVSYGLAPLSYDETYSMIRSLRGYPIIKGTRGQ
                     KGIDEQQYADIIVRLSTLLRFASEIKEMDINPLVATDRGLFAVDARIRIEK"
     CDS             complement(12584..13336)
                     /locus_tag="ctg373_10"
                     /transl_table=11
                     /translation="MCGTCGCGEHHHHHDHMHEHSHGHEHHHHPDEGIVINLEQDILQR
                     NNLLAERNRGYFEAKNLFCLNLMSSPGSGKTTLLEETIRRLKAKRSIYVIEGDQQTSND
                     ADRIAALEIPVFQVNTGTGCHLEADMVNHAVKHLNPKEGAILFIENVGNLVCPAMFDLG
                     ESKKVVIVSTTEGDDKPLKYPHIFQEADICVINKIDLAPYLNTKVEVLRENALKVNHRL
                     QIFEVSATKGDEMDAWCDWLQTESAKCK"
     CDS             complement(13366..13593)
                     /locus_tag="ctg373_11"
                     /transl_table=11
                     /translation="IQTLEFALDSAIKGSKLEKARIIRHYIEGEGQCSDCETIFPMNAL
                     FSPCPHCGSYLVKILKGKELRVKSIVIKKE"
ORIGIN
        1 agaaaaataa tatttacatc actctacaga caagaggggt ataaacgtta tttacagaaa
       61 aagttttaga aacatacgta aagatgcgcc ccttgcgccc taacctatca gcaacatccc
      121 taatacggga tacaaaaaag tcaatgggac acggccgtaa agtcattgag aaaccatctc
      181 tattccattg actttaccac cgtttcccat tgagatacta tcgcaaacca gacacttcaa
      241 ggacggaaac tcattccccg aaaagaaact tacaatcccg ttcggccgcc ggtctcgtcc
      301 aatcctgcgg gatcatttgc cattggttta aaggttgtgg gctaagtaca cccttttcct
      361 ttatatattg aatcatataa taacggaggt ctttatcggt cgaatgaatg atacgactct
      421 ttaactcgtc ttggggaatg ccggcccctt tcgtcaataa ctcacctcct ccattacctc
      481 ggtaagagtt aagagctact ttatacgttt tattctcgtc gaaaggctta ccatccgcca
      541 ttttcaagat cgtgatcttc tcgcccttgg gtttcgttac atccacggtg taaatgatac
      601 cagctgcgga gtcaaagtta aaactgaagt tgacgaatga gacataattc tcctgtcctt
      661 tctttctctc tttcaataat aagacatgat cgtccggaga tttcatccgg ttggtccaca
      721 tagcgtatga ttcctccaag aaacctttga tctcggctcc cgtcaaattc atcgtataaa
      781 gcatattctc atatttgtaa agactgaaca tatcgctgat cgtgatatcc cctttatcta
      841 tttttgcgtc aaaggataac ggggcggcaa aagagacgtc cgcaccagtc aactccaatt
      901 gtaaagagtg aataaaatca ataaaagcgg atggcccaaa gtaagcggga cgggtcgcga
      961 tactctccgt aaaagttccc accttctcgg agacaaaatc attcaccgct ttgtattgcg
     1021 gagcgaattt ctccataaac tccttgctag gctccaactt atccacatcc gtcaaaacac
     1081 ccgatacttg tttgtccaaa acctttccat gctccatctt taacacgaca tcaacggaac
     1141 cgactacacg cccattactt gccggattta tcaataacac ggaatctccc tcgatattcg
     1201 ccaccttacc acaataccgg cgatgatcat gccccattat aaccacatcg aagcccggaa
     1261 tgcgctgggc aacctccatc gacgcatcct cacggtactg gccggacatg gtacgagcct
     1321 catttcccgc atgaaagata cctaccacaa catccggttt ctccttctcc tgaatgatct
     1381 tcatccattt acgggccgtc tcttccatat cggcgaaata aagaccttgc cacagagtct
     1441 ccggcaacca tacaggaata gccggagtaa tcatccccag tacaacgatc ttcacaccgt
     1501 cacgctcaaa tacctcatag ggctttaaat aggtctcccg gtcggaggta cggataatat
     1561 tggcacccaa gatagggaaa tcacattgtt tgatccaacg atcgaaaacg gcatggccag
     1621 cctctacatc atggttaccc atatttcccg cattgtaccc catataattc atcatggcgg
     1681 aagctatatg cgtagagacc gtatccatga aattgtaata atacgccgaa ggttgtcctt
     1741 gcaagatatc gccattatcc aatagcaaaa ggttatcgcc atacgcccgg cgttcttctt
     1801 gcacgaacga atataccctt gccagacttc ctccccactc ccgctgctcg ataaaattat
     1861 acgggaagaa atttccatga atatcactgg tttccaataa tttcaacttt acttccttcg
     1921 ttgtcgccga cagaccgaga gcgaccagca gcaataaggc aattgaataa actcgtctca
     1981 tatcaggatt ttagatagat taatgacgcg aagataacga aataacctgt tcgcccggtt
     2041 tcaacgggat ttcttttcca tcccagataa atatacccgt agtaccttcc ggcaagacca
     2101 gacgggcggt tccctcacct ctttcattca atttataagc ggcggtcacg cttccaagcg
     2161 gatgtgggat cgtaccggaa acctccttca gttttcccaa agacggagcg atccgtatct
     2221 tcctaaatcc gggagcatcg ctatctatcc ccaacaagat ccggtaaaac tcgatattcg
     2281 gactggctcc ccaagcatgg caatcagaac gggatggctc cggcatctct gcccatgtgg
     2341 tcaatcccaa cgccatctga tcccgccata tttgtaagtt atccaagaac tgatccccta
     2401 aaccggaagc tttcaacgct tgattcaagt aataacggaa atagatcgta cactggatca
     2461 agctcgtatc cgccaaggtt tggttcatca cctttacggc ctcctcccct ttcgtaaccc
     2521 cagtcaagat cgccaaggcg ttcacatgct gggaatagct gcgatgatcc tgcgtatcgg
     2581 cgaatagatt acgggcagcg tcccaatatt tcgggcggat cgtcttacgc atctcggtag
     2641 cgatcttccg gtaatgatcc gccatggcag ggaggccgat cgcttgttcc atctccgccg
     2701 caaactccaa ggtcattata tacatcaaat cttggagcgc cgagtttccc tctttctccc
     2761 gtatcggctc gccataatca aaaccggccg cccaatccac gaagaaccaa tgaggaacgt
     2821 acgacaaact ataatccggc ttcaaccatt gctcgtacca cgacaaaacc tgacggtaag
     2881 cgggaagcaa ggtcttcatg tatgcctcat ccccacggta catccaataa tcgtgcccca
     2941 tacaaatcca ccagagagag aacgaggata taaactgatg tacgctagac ggatatcggc
     3001 tcatcgtaat cccttccgcc accatggact gccgtccttg ctctagagca ttcttcacca
     3061 tataagggtc tgatgtatta tacatggaaa tcattgcctg tatgcgtgta tccccgaaat
     3121 attgcagttg ctcgtaatac gggcagtcca tatacgtctc attggcgcac agacgggcgg
     3181 tacgccatcc tatctcgagc atacggccca gctcctcatg tcccggagcg gagaaagcgg
     3241 tctcgttacg gaaaggatag gcggagaaag tcccatacat atcctcgatc accaaaggct
     3301 cggaagccgt cttcactttc aactccacat atctccatgt acgccaccac agggaggtga
     3361 agagacgatt atctccccca tcagccagta tcttatcccc gtacccgata aactgcttat
     3421 ccgtcaactc gtcccgatgt cccttgccat tcaacgcata cgatttagtg gtcgattcct
     3481 cttcttgctt atagagggct tccgaataac cgatatggat ctcggcctcc tttcctttgc
     3541 tgaaggctaa ggagaaataa cccgtcgtca ggtaatcatt atccagaagc aagcggacct
     3601 ccgtattcgc cgggatcgtc aaagcttttg gccagtaagg aaatccttgc gggcattcga
     3661 tcccttccga ccggcggagc ttggccagac gctcgatccg gctgtccatc ggaggtatcg
     3721 ggctaggaac cagcaaccgt cccgggtaat ctctcgatcc tttcgtggca ccctccatgc
     3781 cccgtacggc cttctcccat ttcctgtcgt cgtaatccgg ttgttcccag ccccaaggat
     3841 aagcggaggc ttccagttcc tcgcccgggc cagccacgta ataccccaat acctgccatt
     3901 cggtccaagg agcatacgcc ttattacgca ggcagaccca agtggtatcc gtatttacca
     3961 ccgcctcatg ccccgtattg ccttgcagga taaaacccgt ctgatcgtaa ctgatctggg
     4021 cgacaggttt acgctcggca taattccaga caacggaggc cagcgtattc ttccctttcc
     4081 tcagataagg agccagatcc accgtctcga aactccagtt atagatatcc ccacgggccg
     4141 gacccaagga taccaatttc ccgtttacat ataatttata acggttatcg gcggaaacat
     4201 ggacgataaa ccgggaagga accacctcca gatcgaacga tttacgaaaa tgatagaccc
     4261 catatacatt cggagcctca cccgggtagg agatccaacg ggctttccat cgtccctcga
     4321 aaagagaagg atcgatcttc tcctgattat accctttcag gctaatctgg gaggaaaggg
     4381 agaaggcttg aaacacaaaa agcaaaagga ataaataggt tttcatacaa acacggtatt
     4441 atttgagatt aacgatccga acaaaggtac aaaaaaagag aaagcgccaa aagaactttt
     4501 gccttttgac gctttccctc acaatatacc ggatacccgg tcctccatta gaagaatatc
     4561 tccggctccc ggcgtgcgct aaagttctta tggagcatcg ccgtgtaagg agtatcgaaa
     4621 gtacgtgcgc cctcgggaca ctctttcacg caggcgcaac atttgataca taggttcggg
     4681 tcgctataca taccctcgtc tgccaaggat atcgcatgtg taggacacac atccacgcaa
     4741 tactcacatt gcgtacataa atcgttatcc gtaacaggag cttgaggagt ggaagggcct
     4801 ttcacccgat acgggaaatt acctttcacc tccaaggcgg acaagcattc cacgcaggaa
     4861 accttctcca gctcctcgat aatctttttc ccgaattccg tagcctgctt aagatccgac
     4921 tcgtccggac gcccctcggc aatgggcatc cccttgcggc tgaaagaatg ctcgccgata
     4981 aacgctccgg cagccacagg tacgaacccc tgctccgaca ctaaatcaca gagctctttc
     5041 aaggcatcct cataatcccg gttcccatac agtaccacgg ggactaccgg cgcatggtgg
     5101 gcagaacgga acatgcgaaa acgttccatg gcagtctccg ccacacggcc accgtataca
     5161 ggagcggcta taatcgtcag ctcatcatca atatactctt ccatatccag actctcacaa
     5221 gtgacatcag actcggacat cgaagtggca cccattcctt ccgctatcgc ataagcgatc
     5281 ttggcggacg tgtgtgtcgg agaaaaataa attaaatgta tgttactata tttcatgatt
     5341 cttattttaa cgcaccctct attttagtca ttaactcagc aaattcctca tcggtatagc
     5401 ctttgctcgt ataaatgatc ttcccgtctt ttccgaccaa atagccacga gggatcaagt
     5461 tcttggcgaa agcgccgaaa atagcccggt ccttatcggg atacaatgga aaatcgaagc
     5521 cttttttctc gttatatttc tgtagatcgg catcggaatg ctcacgcccg atcaccaaga
     5581 gaacgaagtc cttgttgttc ttgtatttcg gccagagggt ttgttggaca gcggccaatt
     5641 ctttttggca aggaggacac caagtggcga aaaaattcac gaggatcact tttcccttca
     5701 acgaagcgga ctgcaactta ctcccgttgt cggaaacaat cgtaaatgac ggcatagtat
     5761 caccgacctt cacgatatcg gaattatcct cctgagcttt gcctacgaaa gccaataacg
     5821 ctagtaaact aaccaataaa tacttcttca taaccttaat catttctcgt ttaggattca
     5881 gcgacaaaga tacattaaaa ttctcatcaa accgcataat tctaaggctt acgaaagttc
     5941 tacggtgccg tacctacccc tcgacagctc ttctaaaagt tctagggggt tagatgttaa
     6001 aaaaaacgta cgtgaaaccc ggagatgtca cgtacgctga tatcatgcaa acccggagaa
     6061 agatttaccg cagactttgc gctaagtcat aaccggcttt caacgccttt aggttcatat
     6121 taactatatc ctcgccctta cgaccgaata tctgacggat tcccgcctcg atcttatcat
     6181 actcgatccc gataaatggg gcagctgcac ccaacatcac gatattggcg gcacggacag
     6241 aacccgcttc cttggcgatc tcctccacgt ccaatacgac cttgtgaggg agcctgtcca
     6301 actcggcgtt cactttctcg atctccggat agttcgggat gttcacgaac ggacgggagt
     6361 tcgtcaccag ccaaccctct ttcttcaggt aaggcagata acgcaagctc tccatcggtt
     6421 ccaaagagat gatcaaatcg gcgtggccct tcgggatcaa gtccgaggcg atcggctcgt
     6481 cggaaagacg caggttagac tgcacgtctc ccccccgttg actcataccg tgtacttccg
     6541 cttgcttcat atacagacct tcttttaagg cagcttctcc aataacggcg gcgatagaaa
     6601 ggataccctg tcctcctacg cctgatagta taatatctgt tttcatttct tgcttgcttt
     6661 tttctttctg gttaatgtct ggatacactc acggcgaggg atcaatacgg atacgccctt
     6721 gtactcgatt tcctcacgga tgatagactt catctcctcg aagttctttt ttaaaggaac
     6781 catcacacgg atgtgagccg ggtccacacc gataccggcg cagatagatt ccagacgtcc
     6841 cgttccggcg gaatcctgcc ctccggtcat ggccgttgtc tcattatcgg agataacgat
     6901 ggtgatattc gtgttctcgt tcacgcaatc cagcaaacca gtcataccgg aatgggtaaa
     6961 cgtagaatcg ccaatcacgg agatagccgg gaatacaccc gcgtcggaag cacccttcgc
     7021 catcgtgata gaggccccca tatcgataca agaatcgatc gcacggaaag gaggcaaagc
     7081 tcccaaggta taacagccga tatcgccaaa caccttagcc gtaccgttat actcggcgat
     7141 cacctcgttc aaggcctcat acatatcccg gtgtccacaa ccttggcaca atgcgggcgg
     7201 acgttgctca accacctcgg ggatcgcata atagctctgg atctccttac ccaaggcttt
     7261 gcctaccgcg tctggcgtaa gctcgccgtc acgctgaagc gtaccgtcca gacggccatg
     7321 aaccgtcacg cctttcgcca agaaaccttt taattgctct tcaacgaccg gatatccctc
     7381 ttccaacacc aagatctcct tacactcgcc aacgatcttc tccacttgct ttctcggaag
     7441 cggatactgg gagatcttca atacgggatg ctcgaaaccg tccggataat tctcggaaag
     7501 ataattgaaa gcgatacccg tcgtgatgat acccaagtct ttattcgggg catcgaaata
     7561 cttattatat gcggaattct cggaagcttc cgtgaaagcc tcttgagacg ccagcaaact
     7621 cttgaaacgt ttacgggcca atgccgggag taagataaaa cgttgacgac cgtcttccgg
     7681 acaattcatc cggttctccg gcttcaacgg gctggttacg acaccggcac gagaatgcgc
     7741 catacgggtc gttacacgca gcaagatagg ataccctaat ttctcggata actcgaatcc
     7801 atgatatacc atatcataag cctcttgctg gctggatggc tcaaacatcg ggatcatggc
     7861 gaaattgcca taaacacggt tgtcttgctc attctgggaa gagtgcatgg atgggtcgtc
     7921 ggccgtaagg atgatcatac ctccgttgat accgctcata gcggcgttca taaagcaatc
     7981 ggcggctaca ttcaaaccca cgtgcttcat gcagcaaagc gcacgtttac cggcatagca
     8041 catacccaaa gcggcttcca tggcggtttt ctcatttgtg ctccagcgac aatggatacc
     8101 tctttccttc gttaccggag aaccttggat atattctgtg atttcagtag aaggggttcc
     8161 cgggtatgcg tacaccccgg agattccagc gtctatagcg gcttgcgcta tggcctcgtc
     8221 ccccaaaaat aaatgttttt ccatgtgtat ctgttttctt aatattgact attcacacta
     8281 tttagctgcc aaaggtaatg aaaaatgttc aatttagaat gagagactta tgatttatac
     8341 tagatccatt accgtatccg gcgcctattc aactccgccc gataccggtt ggcattgcgg
     8401 ttatgctccg ccaacgtcac ggcgaaatta tgccgtcccg agaaatcctc cttagcgcac
     8461 atgtataagt atttatgttt cgtatgattc aatacgctat tcaagccctt gatagtagga
     8521 atccgtagag gaccgggagg taggcccgca tatttatagg tattataggg agaatctatt
     8581 tccaaatgct caaataagat acgttgcaaa gaaaaatccc ccaccgcaaa ctttacggta
     8641 gggtccgcct gtaaaggaat accggcacga aggcggttga tataaagacc cgccacgatt
     8701 ggatattcgt ccgatgccgc cgtctcctct tctacgatag aagccaagat agatacctca
     8761 actggagtaa gcccgatctc ctctgccttt ttcaatcgtt ccggtgtcca gaaagcgtca
     8821 tattcacgct tcatgcgacg tataaattta tccgcggata tattccaata aatctcatag
     8881 gtattaggaa tgaaaagggc atggatcgtt tccggggtaa aacctaaaga gtcgcaatac
     8941 acggaatcat tcaatagacg caggagattt tccttcccga acatcaattg atcacttata
     9001 cgttccgcca aatcttcctt gaaacggata ttattaaaag taacccgggt cgctacttga
     9061 tgtcctctcc gcaagtcatt caataaggtt aaattactca tgccgggttt cacggcgtat
     9121 cgaccggtac gcatggacgc aggatacttc aacaatccac tcaattgctt aaagctaccg
     9181 atacggagac agttcgccga atcactcaac tgccggcaaa gatcatcaaa atccttttta
     9241 tcatctatat agacatagac cgtcttatcc ggcttaaaat tcggagccca agccaaacgg
     9301 tacacccaaa agcctccacc gcctatcaaa acaacgagaa tcgctatcaa ggcgataatt
     9361 atcggacgcc tcgataaaat ttgtttgttc aaatccatga ataatctatt gaatatcaga
     9421 ataaggcaca aaagtagtat cttttttcga aaaaaatgat gtgcaaagcc ttgtttattt
     9481 aaaattatag ttctaccttt gcatcgcaat tctaaggaag aagcacagaa cacacaagga
     9541 agtgtgggtg agtggctgaa accaccagtt tgctaaactg acgtactcgt tagggtaccg
     9601 ggggttcgaa tccccccgct tccgcaaaga gccaactaat aaatttatta gttggttttt
     9661 ttgtttttaa gccaaccgaa ttaaagtgtt tcatatattt gtcatatttg aacttatcgt
     9721 aagtcgatct gttattaaaa ggagataatt aaatatatac attatgacaa ttgcttttat
     9781 ccgaacatat aacaataagc aaaactccga ggtccaagaa gctgtgatcc gggaatttgc
     9841 agaatctcag aagatagaga tcgggaagtg ggctaaagag gtgggaaata gtcctcgtgc
     9901 gaaccgcaga ctggaaagta ttgtcaaatc tttaagtccc ggggatgaga tacttgtgtc
     9961 cgatatatcc cgtgtgagcc gtaagatgat cgagatcatc catatcattt tgctttgtat
    10021 agagcgaaag gtaacgctcc gtagcgtaag cgacggatat gtgttcgagg ataatatcga
    10081 cagtaagact ttggccttta ccttcggtct ggtctctgag atcgagcgaa agctggtctc
    10141 tatccgtacg aaggaagccc ttgccttgat cagaagtaaa ggtgtggtgc tgggccgtcc
    10201 gaaaggtagt caacaaatgg gacgcttgga gccttataag gaacaaatcg agaaagactt
    10261 gaaagacccg agcttgactt acgctcagat agcggagaaa tacaatgtat cgttaagtag
    10321 cttcaaacgc tttctgaaag agtatcttcc cgataagaaa aagaagaaga ctaaaaaata
    10381 agaaaagctc ctttcacctc tgctaagtat attagcattc agtagtgaaa ggagcttgtt
    10441 tttttatttc tctatacgga tacgggcgtc tacagcgaac aagcctctat ccgtagccac
    10501 caacggattt atatccattt cctttatctc gctggcaaaa cgcaataagg tagagaggcg
    10561 aacgataatg tccgcatatt gttgctcgtc gatacccttt tgcccacgtg tacctttaat
    10621 gatcggatac cctctcaaag aacgaatcat tgaataagtc tcatcgtatg acaacggagc
    10681 caaaccataa gacacatctt tcaatacctc cacgaagatt ccacccaacc cgcaaagtac
    10741 cacatggccg aaacgatcct catatttagc tcccaagaat aattcctgtc ctttcaacat
    10801 cggttgtacc atgatgcccg taacacccgg cagacgcatc atacgttcat actcgaacaa
    10861 taaatgctct tctccacgga tattcaaggc cacaccaccg atatcgctct tatgcacagg
    10921 ccctacaacc ttggctacca ccggatattt caccttcttg gcaaaagcca gcaacgcatc
    10981 cctatcatcc gaagcatatt cctccactaa cgggatatta gcggcacgca acaatgtacg
    11041 cacttcctcc ggatttaaat aaccgctacc cggcaaccga tctatgatac gacgaacttc
    11101 cggtacatcc acgccatata gctggatatc cgtgctcatc ggtttcggcg tattgatcac
    11161 ccgtgaaagg gcagtaccca atgtcacctc gtccgagaag ttcacatggc ctttcttgac
    11221 aaagctcttc acctccggtc cggccgttac gatagacggt aatatcggga agatcggctt
    11281 cttgcactct tccatctttt tatgaagtac ctcgtaggta tcataaagtt ttaccaaacc
    11341 gggactaccg aagatgacca tcatcaaatc cacattatcg aaacgattct cacagaaatc
    11401 gatggctgta gccagatgtt ccggtgtccc cgtaccgata atatcaatcg gattaccgac
    11461 agcggcaccc ggatacagtt tggatttcaa ctcatcagcg atagggcctt ccaaactagg
    11521 gacattcaaa cgccccttgg ataaggcgtc cgccagcatt accgcaggcc ctccggcatg
    11581 tgtcacgatc gcacaattct tccctttcac gtctttcaag gtaaagatac tcgccacggt
    11641 agtcaattcc tcacggctaa aacaacgcac gatacccgcc ttacggaaca aagcctccac
    11701 ggcagagtcc gaactagcga tagcgcccgt atgcgaagag gcagctcgct ttcccgactc
    11761 cgtacttccc gccttgatag cggcgatctt gcatccctta cgtatcaagg aagacgcatg
    11821 atacaacaat ttatccggtt gcttgatttg ctcgatatac aacatcttga tcttggaatc
    11881 caataccgga tcaaagttcc gatccatata ttcaaggata tcctctactc cattctgctt
    11941 ggagtttcca accgaccaaa cagaagagaa acgcagccct tttgtcagcg ccgactcgat
    12001 aatgaacaag gccgtaccgc cggagctaga gatgaaatcc acgccatcgg gatggaattc
    12061 cggtatcggt tgcgtaaaca cgccatgata attcatattc atcaacccga tacagttcgg
    12121 gccgatcaag gaagctcccg cctcattcac gacatccagc atctgttgtt ccaagatacc
    12181 gccttcgtgt gtctcctcgc cgaaaccggc tgagatcacg ataaaagctt ttaccccctt
    12241 ttgccgggcc agcacttcca tcacctcggg gcacgattta ctcggaatcg agatgatcgc
    12301 caactccgtc tccgggatat catgtacaga aggataagac ttgacgcctt gcacgtctgt
    12361 ctccttggcg tttaccacac ataattctcc tttatatttt ccatccaaca ggtttcgcac
    12421 gatacgaccg cccggtttat gtacgttgtt ggaacctccc accactacga tgctttgagg
    12481 attaatcaat tctcggttaa tcataacatt ttgattagtt agattcaatg aatgggagca
    12541 aatatagttt ttttctccat ttattcatta aaacccgggg tatttattta cactttgcac
    12601 tctctgtctg caaccagtca caccatgcat ccatctcgtc tcctttcgtg gcggatacct
    12661 cgaatatctg gagacggtga tttaccttca aggcgttttc ccgaagcact tccacttttg
    12721 tattcagata aggagccaga tcaatcttgt tgattacgca gatatctgcc tcctgaaaga
    12781 tatgtgggta tttcaacggt ttatcatctc cctccgtcgt actcacgata acgactttct
    12841 tggactctcc gagatcgaac atggccggac agaccagatt gccgacattc tctataaaaa
    12901 ggatcgctcc ctccttcgga ttcagatgct taacggcatg attgaccatg tcggcttcca
    12961 aatgacagcc ggtaccggta tttacctgaa acacgggaat ctccaacgcc gctatacggt
    13021 cggcatcgtt tgaggtttgt tgatcgcctt ctatcacata gatcgatcgc ttcgctttca
    13081 aacggcggat cgtctcttcc agcaaggttg tcttaccgga tccgggcgaa ctcatcaagt
    13141 tcaggcagaa caggttctta gcctcgaaat atccccggtt tcgctccgcc aataagttgt
    13201 tacgttgaag tatatcttgt tccagattga ttacgatccc ttcatcagga tggtgatgat
    13261 gttcatggcc atgagaatgc tcatgcatat gatcgtgatg gtgatgatgc tctccgcatc
    13321 cgcaagttcc gcacatagta tttaagtttt tatttcatta atatatcatt cctttttaat
    13381 aacaatcgac ttcacccgaa gttccttccc tttaaggatt ttaactaaat aggagccaca
    13441 atggggacaa ggggaaaaca aggcgttcat tgggaaaatg gtctcacagt cgctacactg
    13501 tccttccccc tcaatataat gacggataat ccgggccttt tccagcttgc taccttttat
    13561 ggcgctatcc aatgcgaact ctaaggtttg gatc
//
