Select genomic region:
Overview
4.1
11.1
13.1
18.1
22.1
33.1
33.2
48.1
49.1

### Identified primary metabolite regions

c00004_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_4)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 4.1 | Rnf_complex | E-MGC | 28,702 | 53,762 | Rnf complex C. sporogenes | RNF | 83%

c00011_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_11)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 11.1 | TPP_fatty_acids | Putative | 176,549 | 201,406 |

c00013_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_13)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 13.1 | succinate2propionate | SCFA | 79,140 | 103,667 | Succinate to propionate B. theta | PRO | 50%

c00018_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_18)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 18.1 | OD_unknown | Putative | 45,446 | 68,772 |

c00022_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_22)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 22.1 | Fumarate2succinate | SCFA | 56,697 | 80,161 | Fumarate to succinate B. thetaiotaomicron | SUC | 100%

c00033_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_33)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 33.1 | Arginine2putrescine | Aliphatic_amine | 65,354 | 95,995 |
Region 33.2 | TPP_AA_metabolism | Putative | 124,343 | 150,309 |

c00048_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_48)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 48.1 | Pyruvate2acetate-formate | SCFA | 141,207 | 164,182 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%

c00049_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_49)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 49.1 | porA | SCFA | 85,709 | 108,544 | porA C. sporogenes | POR | 60%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 4.1 | Rnf_complex | E-MGC | 28,702 | 53,762 | Rnf complex C. sporogenes | RNF | 83%
Region 11.1 | TPP_fatty_acids | Putative | 176,549 | 201,406 |
Region 13.1 | succinate2propionate | SCFA | 79,140 | 103,667 | Succinate to propionate B. theta | PRO | 50%
Region 18.1 | OD_unknown | Putative | 45,446 | 68,772 |
Region 22.1 | Fumarate2succinate | SCFA | 56,697 | 80,161 | Fumarate to succinate B. thetaiotaomicron | SUC | 100%
Region 33.1 | Arginine2putrescine | Aliphatic_amine | 65,354 | 95,995 |
Region 33.2 | TPP_AA_metabolism | Putative | 124,343 | 150,309 |
Region 48.1 | Pyruvate2acetate-formate | SCFA | 141,207 | 164,182 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%
Region 49.1 | porA | SCFA | 85,709 | 108,544 | porA C. sporogenes | POR | 60%

No primary metabolite regions were found in these records:
  c00001_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_1)
  c00002_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_2)
  c00003_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_3)
  c00005_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_5)
  c00006_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_6)
  c00007_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_7)
  c00008_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_9)
  c00010_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_10)
  c00012_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_12)
  c00014_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_16)
  c00017_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_17)
  c00019_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_21)
  c00023_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_23)
  c00024_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_30)
  c00031_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_31)
  c00032_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_32)
  c00034_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_34)
  c00035_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_39)
  c00040_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_40)
  c00041_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_43)
  c00044_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_44)
  c00045_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_45)
  c00046_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_47)
  c00050_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_51)
  c00052_gnlPro.. (original name was: gnl|Prokka|NCBOLKND_52)

Compact view
c00004_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 28,702 - 53,762 nt. (total: 25,061 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00011_gnlPro.. - Region 1 - TPP_fatty_acids
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 176,549 - 201,406 nt. (total: 24,858 nt) Show pHMM detection rules used
TPP_fatty_acids: (TPP_enzyme_C and (minimum(2, [ACD1_car, ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro, Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, Carboxyl_trans, CoA_trans, CoA_trans_230_acto, CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1, ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C, Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and not (POR or POR_N))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00013_gnlPro.. - Region 1 - succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 79,140 - 103,667 nt. (total: 24,528 nt) Show pHMM detection rules used
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00018_gnlPro.. - Region 1 - OD_unknown
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 45,446 - 68,772 nt. (total: 23,327 nt) Show pHMM detection rules used
Region on contig edge.
OD_unknown: (minimum(1, [PFOR_II, POR, POR_N]) and minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC, Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical or Gly_430_pcre or Gly_8-9_TMA))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00022_gnlPro.. - Region 1 - Fumarate2succinate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 56,697 - 80,161 nt. (total: 23,465 nt) Show pHMM detection rules used
Fumarate2succinate: (Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or Fer4_7 or SucD_FumR))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00033_gnlPro.. - Region 1 - Arginine2putrescine
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 65,354 - 95,995 nt. (total: 30,642 nt) Show pHMM detection rules used
Arginine2putrescine: (minimum(3, [AdoMet_dc, Amidinotransf, Arginase, OKR_DC_1, OKR_DC_1_7_arginine, OTCace]) or ((OKR_DC_1_5_ornithine or OKR_DC_1 or Orn_Arg_deC_N) and minimum(1, [Arginase, OTCace, OTCace_N, PAD_porph])))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00033_gnlPro.. - Region 2 - TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 124,343 - 150,309 nt. (total: 25,967 nt) Show pHMM detection rules used
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00048_gnlPro.. - Region 1 - Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 141,207 - 164,182 nt. (total: 22,976 nt) Show pHMM detection rules used
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00049_gnlPro.. - Region 1 - porA
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 85,709 - 108,544 nt. (total: 22,836 nt) Show pHMM detection rules used
porA: (Fer4_7 and TPP_enzyme_C and POR and POR_N and PFOR_II and not (EKR or Fer4_16))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.