LOCUS       gnlProkkaMHMFAJIL_71    5858 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MHMFAJIL_71.
ACCESSION   gnlProkkaMHMFAJIL_71
VERSION     gnlProkkaMHMFAJIL_71
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 08:23:33
            Original ID  :: gnl|Prokka|MHMFAJIL_71
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5858
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5858
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[340:858]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      341..858
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..5858
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..5858
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(38..205)
                     /locus_tag="ctg71_1"
                     /transl_table=11
                     /translation="MDKIISIIIVILILLATIAFYLAPFVGGLWQGAARSKVIAKILPQ
                     FTIQVQHPDD"
     CDS             complement(341..556)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_2"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.3e-09,
                     bitscore: 29.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISKEVGITLKQHDLVLIQGGAKRRNKPSGCIVSTIGGAVAGAAG
                     LNPFTTVAGAAIGLSLCLSTNYIHPA"
     CDS             complement(553..858)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_3"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.2e-15,
                     bitscore: 46.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYVKDSKVDLTQNSLLLFEERRKIMSYNYRQLDDFQLSGVSGGKK
                     KFDCAATFVTGITAGIGSGTITGLAGGPFGIIGGAVVGGNLGAVGSAIKCLGDGMQ"
     CDS             complement(1058..2011)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     220.3; E-value: 5.2e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_4"
                     /transl_table=11
                     /translation="MKQVRLGGFNWQASSVALGIMRMNVLAPDKAANVLDSAYNDGINF
                     IDSADIYGQGKSEEVFGEALKQASVSRDQLFIQSKVGIVVDPKRSHGSLVFGKRYDFSK
                     DHLLSAVDHILKRLQVDYLDSVLLHRPDPLMEVDDVAAAFDALEQSGKVRHFGVSNFNP
                     EQLALLESGIRQPLLIDQVQFSVAHTGMVNAGMHTNMADAASVDHDGSLLPYLQRKHMT
                     LQAWSPFQYGMFEGTFIDSPKFKALNDELQKVADHYHTNKNAIAVAWLLRHPVGVQVIL
                     GSMNPEHIKESAEGADITLTRQEWYDIYFAAGNDLP"
     CDS             2201..2950
                     /NRPS_PKS="Domain: PKS_KR (11-174). E-value: 4.2e-12.
                     Score: 38.2. Matches aSDomain:
                     nrpspksdomains_ctg71_5_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     192.8; E-value: 1.2e-58)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_5"
                     /sec_met_domain="adh_short (E-value: 6.5e-35, bitscore:
                     111.5, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAVILTVKDKVVVITGASSGIGAATVQVLAEAGAKLVIGARRTE
                     RLAELAASFTDGQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAEL
                     KVNEWERMIDVNIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWA
                     IQAIMDGLRQEQAANHIKTTMISPGAVNTELFSTITDPKRREAVEADEKNNGLSASDVA
                     KAVLYAIDQPANVAINEVLLRPVTQER"
     aSDomain        2234..2722
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg71_5_PKS_KR.1"
                     /evalue="4.20E-12"
                     /label="ctg71_5_PKS_KR.1"
                     /locus_tag="ctg71_5"
                     /protein_end="174"
                     /protein_start="11"
                     /score="38.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVVITGASSGIGAATVQVLAEAGAKLVIGARRTERLAELAASFTD
                     GQVLYQQTDVTDQQQVKALIDLALDKFGHVDVLYNNAGLMPLSEMAELKVNEWERMIDV
                     NIKGVLYGIAAVLPPMIAQHSGQIITTDSVAGHIVHPGTAVYSGTKWAIQAIMDGLRQE
                     "
     CDS_motif       2237..2317
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg71_5_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg71_5"
                     /protein_end="39"
                     /protein_start="12"
                     /score="14.1"
                     /tool="antismash"
                     /translation="VVITGASSGIGAATVQVLAEAGAKLVI"
     CDS             2976..4139
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217:NADH:flavin oxidoreductase/NADH oxidase (Score:
                     282.1; E-value: 9.6e-86)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_6"
                     /transl_table=11
                     /translation="MSGYHFLKRFTFKHQTITLKNRIVIPPMTTRLSFEDGTVTRDEIR
                     YYQQRAGGVGMFITGTANVNALGKGFEGELSVADDRFIPGLSKLAAAMKTGGTKAILQI
                     FSAGRMSNSKILRGEQPVSASAVAAPREGYETPRALTSAEIEATIHDFGQAVRRAILAG
                     FDGIELHGANTCLIQQFYSPNSNRRTDEWGGDRDKRMRFPLAVVHEAEKVIATIADRPF
                     LLGYRISPEELEQPGITLDDTLALIDALKQTKIDYLHVSQSDVWRTSLRNPEDTAIMNE
                     QIRDHVAGAFPVIVVGGLKTPADAEKAADSFDLVAIGHEMIREPHWVQKVLDHDEKAIR
                     YQIAPADLEELGIAPTFLDFIESISGGAKGVPLTTAQSMTSSNVPQD"
     CDS             complement(4401..5777)
                     /locus_tag="ctg71_7"
                     /transl_table=11
                     /translation="MSKYRTETDTLGPVEIPANALWGPQTERSRHNFQAGPLMPMPVIR
                     ALLQLKKAAARANVAADVLPAPKGQLITRAVDALLALPDEKLQKDFPLHVYQTGSGTQT
                     NMNVNEVISHQAAKLNPDLPILPNDDVNHSQSSNDTFPTVMNITAAIAVNQLLHAVNQL
                     CSVLYSKAVTYARVVKIGRTHLQDATPLTFGQEISGWVAMMEHDQIALKQLQPNLFYLA
                     IGGTAVGTGLNADPNFGKIVAGRLSDVYQLPLSAKTNKFAALAAHSEISVVHGAVKTLA
                     ADLLKIANDIRFLASGPRAGYGELRIPANEPGSSIMPGKVNPTQAEALTMAAVRVMGND
                     TTITVAASQGNFELNVYKPVIISTFLESADLLTKTVTSFTEKLAAGLTIHAPHMRALVD
                     HSLMLVTALAPHIGYEKSAAIAQLAEQENLDLKAAAIKSGDVTAAQFDKWVDPLKMTRA
                     "
ORIGIN
        1 agcactaaca agaataggtc ttcatggcct ttatggtcta gtcgtcaggg tgttgcactt
       61 gaattgtaaa ctggggaagt atcttggcaa tgactttgct tcttgctgcc ccttgccaaa
      121 gtcctccaac aaatggtgct agataaaaag cgatcgtcgc cagtaaaatc aagataacta
      181 tgatgatact tattatctta tccatttgta tttcctcttc cttttgcaca aatagactaa
      241 tttgaaatcg atctttgact aagacaagaa aaagtgagca ctaccaaggt gttagttata
      301 ttgaacagtt gcgataggag ctaaccgtct ttgtccaata ttaggctggg tgaatgtaat
      361 tagtgctgag acacaaggat aatcctattg cagcgcctgc aacagttgta aatggattta
      421 atccagctgc ccctgctacc gctcccccga tcgtggacac aatacaccca ctaggtttat
      481 tgcgtcgctt ggctcctcct tggattaaga ccaaatcatg ctgttttaaa gtaatgccca
      541 cttctttact tatcattgca tcccatctcc taagcattta atagctgacc caaccgctcc
      601 taagtttcca ccaactacgg cgccgccgat tatcccaaaa ggaccaccag ctaggccagt
      661 aatcgttcct gatccaatac cagccgtgat gccagtaaca aatgtagcag cacaatcaaa
      721 tttctttttc ccacctgaaa cccctgacaa ctgaaaatcg tcaagctggc gataattata
      781 agacataatt ttccttcttt cttcaaaaag caacaagcta ttttgtgtaa ggtcgacttt
      841 actgtcttta acatacatta attatttgtg taaaatgcca aaatttttta aacgtaggaa
      901 atttccagtt taacgtcgtc tttacacttt tattgttcag ttgcgcttta aaagtcaaaa
      961 attcttaacg tttaaatctc cttgcttggt aaaaacttca attttttgca aaaaaaatcg
     1021 tctcagcaat ttgagacaat tttttcatat catcaactta cggcaagtca ttccccgccg
     1081 caaagtaaat gtcataccat tcctgtcggg tcaacgtgat gtccgcgcct tccgcacttt
     1141 ccttgatatg ttcaggattc atagagccga gaatcacttg cacaccgact ggatggcgta
     1201 atagccaagc gactgcgatt gcatttttat tggtatggta gtggtcagcg actttctgca
     1261 gttcatcatt caacgcctta aacttcgggc tatcgatgaa ggtaccttca aacatgccgt
     1321 attggaatgg cgaccaggct tgtaaggtca tgtgtttgcg ttgcaagtat ggtagcaggc
     1381 tgccgtcatg atcgacagaa gccgcgtcgg ccatgttggt gtgcatcccc gcattgacca
     1441 taccagtgtg cgcaacggag aactgaactt ggtcgatcag caaaggctgc cgaatgccgc
     1501 tttcaagcaa cgcaagttgt tcagggttaa agttggagac gccaaaatgc cgaaccttgc
     1561 cgctttgttc caatgcatca aaggccgccg caacgtcatc gacttccatt aacggatctg
     1621 gccgatgcag caagaccgaa tcaaggtaat caacctgcaa ccgtttcaaa atgtgatcaa
     1681 ccgctgacag taagtgatct tttgaaaagt cgtaccgttt gccgaatacc aaactgccat
     1741 gagagcgttt tggatcaacg acgatcccga ctttcgattg aatgaataac tgatcgcggg
     1801 aaacgctggc ttgcttcaag gcttcaccaa aaacttcttc ggatttgcct tggccataaa
     1861 tgtcggccga gtcgataaag ttgatgccgt cattgtacgc actatccagc acattggccg
     1921 ctttgtcggg ggccagcaca ttcatccgca tgatgcccaa ggccacactt gacgcctgcc
     1981 aattgaatcc gcctaatcga acttgtttca taaacacaaa actcccttcg atacgtcatt
     2041 tcaaattatg ttactgacga caagttaagt gtagccccta aagtccactt gaggtcaagc
     2101 caatattaga atttcaataa aacagcttgc atggtgctga gctgcgcggt aggttaagct
     2161 gtgtctgtta cttatttttt cttagcagga taagcccata atggaggccg tgattttgac
     2221 agttaaagat aaagtggttg taatcacagg tgcatcgagc gggattggcg cggcaacggt
     2281 acaagtgttg gccgaggctg gtgcaaaact agtcatcggt gcgcggcgca cagaacggtt
     2341 ggctgaattg gcggccagct ttacggacgg tcaggtgctt tatcaacaaa ccgatgtgac
     2401 cgaccagcag caagtgaaag cgctgattga tttggcgttg gataagtttg gtcatgtgga
     2461 tgttttgtat aacaacgctg gcctgatgcc actttctgaa atggccgaac tcaaagtcaa
     2521 cgaatgggaa cgtatgattg acgtcaacat taaaggcgtc ttgtatggga tcgccgcggt
     2581 tttaccgcct atgattgctc aacacagtgg ccaaattatc acaacagact cggtcgccgg
     2641 tcacattgtt caccctggaa ccgccgttta ctccggtacc aagtgggcta tccaggcgat
     2701 catggacggc ctgcgacaag aacaagcggc taatcatatt aaaacgacca tgatctcgcc
     2761 cggtgccgtg aatactgagc ttttcagcac aattaccgat cctaagcgcc gtgaagctgt
     2821 tgaagccgat gaaaaaaaca atggcctcag cgcctcggat gttgccaagg cagttttgta
     2881 tgccattgat caaccggcca atgttgccat caatgaagtg ctcttacggc cagtcacgca
     2941 agaacgttaa ttttcgtcta aaggagtgtg attgcatgtc gggttatcat tttttaaaac
     3001 ggttcacctt caagcaccaa accatcacgt tgaaaaatcg cattgtcatt ccgccgatga
     3061 caacgcgcct gtcgtttgaa gacggcactg tgacgcggga cgaaatcagg tattaccagc
     3121 agcgggccgg tggcgtcggc atgtttatta ccggtaccgc caatgtcaat gcgcttggca
     3181 aaggattcga aggtgagcta agtgtcgctg atgatcgatt catccccggt ttgagcaaac
     3241 tcgccgctgc gatgaaaaca ggcggcacca aggctatttt gcaaatcttc agcgctggcc
     3301 gcatgagcaa tagcaagatt ctgcgcggtg agcagccagt cagtgccagt gcggttgctg
     3361 cgccacggga gggttacgaa acaccgcgcg cattgacatc ggcagaaatc gaggccacta
     3421 ttcacgattt tggtcaggct gtgcgccgcg ccatccttgc tggttttgat ggcatcgaac
     3481 tgcatggtgc caacacctgt ctgatacagc aattctattc gccaaactct aatcgccgaa
     3541 ccgatgaatg gggcggtgac cgcgataagc ggatgcgttt tccgttggca gtcgttcatg
     3601 aagcagaaaa agtgattgcc acaattgctg accggccatt tttgttaggc taccgcattt
     3661 cgccggaaga gttggaacag cctggcatta ccttggatga taccttggcc ttaatcgacg
     3721 ctttgaaaca aaccaagatt gattacctgc atgtctccca aagtgacgtt tggcgaacct
     3781 cattgcgcaa ccctgaggac acagccatca tgaatgaaca aattcgtgac cacgtcgccg
     3841 gtgcttttcc agtgattgtg gttggtggtc tgaaaacgcc agccgatgct gagaaagcgg
     3901 cagattcctt tgacttggtc gccattggtc acgaaatgat tcgcgagccg cactgggttc
     3961 agaaggtctt agaccatgac gaaaaggcga tccgttacca gatcgcccct gctgatcttg
     4021 aagaacttgg cattgcgccg accttcctcg attttatcga aagtatttcc ggtggggcaa
     4081 aaggtgtccc gttaacaact gcgcagtcta tgacatcaag caacgtgcct caagattaat
     4141 ctagcatttc aaatcatcgt gcgagtcgag ctgtaaaaag ctcggctttt ttcttgccgt
     4201 cttcaactta cgcgatggtg cctggagcta ccagtgattt ataagtttta aatcaaggtg
     4261 tgatcatcac ctgctcacgc tctgatttaa acgcgttcac cagcgcagct cggctatgcg
     4321 aagaacagtg acacagatgg tccaaagccc agaccatctg tgtcactgcc acttcgctac
     4381 gccgagctaa ccgcgccagc tcacgctctt gtcattttta acgggtcgac ccatttatca
     4441 aactgcgctg ctgtgacgtc gccgcttttg atggcggctg cttttagatc gaggttttct
     4501 tgctcagcca attgcgcgat ggcggcactt ttttcgtagc cgatgtgggg tgcgagggcg
     4561 gtgaccagca tgagcgaatg atcaacgagt gctctcatat gcggtgcgtg gatggtcaag
     4621 ccggcagcta atttttcagt gaaactcgtg actgttttgg ttagtagatc agctgactct
     4681 aaaaaggtac tgatgataac cggcttgtag acgttcaatt caaaattgcc ttgtgacgcg
     4741 gccaccgtga tcgtcgtatc gttgcccatg actcgaacag cggccatggt tagcgcttcg
     4801 gcctgtgtgg gattcacttt gcccggcatg atggaactac caggctcatt ggccggaatg
     4861 cgcaactcgc cgtatccagc acgtggacca ctggcaagga agcgaatgtc attggcgatt
     4921 ttaagcagat cagccgctag cgttttaacg gcaccatgaa caacgctaat ttctgagtga
     4981 gccgctaaag cagcaaactt attggttttc gccgaaagtg gtaattgata aacatcgctc
     5041 aatcggcccg ccacaatctt gccaaaatta gggtcagcgt taagccccgt tccgactgct
     5101 gttccgccaa tggctaagta aaaaagattg ggctgaagct gctttaaagc aatctgatca
     5161 tgctccatca tggccaccca tccgctgatt tcttggccaa acgttagcgg cgttgcatcc
     5221 tgtaaatgag ttcgaccgat tttaacaaca cgagcgtaag tgacggcttt tgaatataaa
     5281 acactgcaca gttggttgac agcgtgcagc aactgattca ctgcaatagc cgccgtaata
     5341 ttcatcacag ttggaaaagt atcattggag ctttggctgt gattcacatc atcattcggt
     5401 aagatcggca agtcggggtt gagttttgca gcttggtggc taatgacttc gttcacattc
     5461 atatttgttt gtgtgcctga cccggtttga taaacatgca gtggaaaatc tttttgcagt
     5521 ttttcgtctg gcaaggccaa caaggcatcg actgctcgcg tgattaattg gccttttggt
     5581 gccggtaaaa catcagcggc cacatttgct cgcgctgccg cttttttgag ttgcagcaag
     5641 gccctaatca ctggcatcgg catcaatgga ccagcctgaa aattatgccg gctgcgctct
     5701 gtttgcggtc cccacaaagc gtttgccgga atttcaactg gtcctaatgt gtccgtttct
     5761 gttcgatatt tgctcatgtt tacctccgtc atcaccatca gaaaaattca accaacatgc
     5821 ctatttgcat agacctattt tacacgaatt cgccgacg
//
