LOCUS       gnlProkkaJNNEHKAM_13   17515 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JNNEHKAM_13.
ACCESSION   gnlProkkaJNNEHKAM_13
VERSION     gnlProkkaJNNEHKAM_13
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:33:28
            Original ID  :: gnl|Prokka|JNNEHKAM_13
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 72297
            Orig. end    :: 89812
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17515
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10567]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10567
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..17515
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17515
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(401..1201)
                     /locus_tag="ctg13_70"
                     /transl_table=11
                     /translation="MKLYKKKILNVNVGKCLLVSLITFVIRYFYANVYLGFHNSLVTIT
                     EGVRSQIYFGGILIDHSFDLISLSFFAILFILEICYLTMDLFNDANDNMVILLPRYGKK
                     HIIYKDILIKMILRDCIVVVSDYLFFLFVEHTSNGLEDFKVIFMLLIEIFHLQMISYLF
                     SFWKDSIIGYIVAFIVFFIPVMVCGFYFSMGNVIWKIWHYSLLHIPLFNWHNKLIIYYV
                     EENYEWTTSNIDLLNFKSSCLISVISSAVLVWIGKFLCEKKQIL"
     CDS             complement(1188..2018)
                     /locus_tag="ctg13_71"
                     /transl_table=11
                     /translation="MKKMVLIEIKHCIDRAEYKVVFIALMILNIASYILCVKNDIGKSY
                     QFIRSANENFVLQGTEAAYIPYIMYLLLPVYATIIASLSLIREEKSNSSILLIQRIGKK
                     KYLAGKLFGILIVTFLTITIPMLINLLLCHLTYPIHGYDSAWGEPDYAIGLVSYNADNF
                     LDMVRLQHPTLYNLIYIFNYGIFGSGLAILAYALSYYNKMKVLYFAKIPGALFIFYIVF
                     NLIVSVFGLNEFSIQGYIMPNVHGNIIGEIVLILLIFGLSIGIIQRKIKNYEVI"
     CDS             complement(2073..2492)
                     /locus_tag="ctg13_72"
                     /transl_table=11
                     /translation="MMLKSLKQKIAKVGIGLFCAGCVFLSSAAYSQAASYTAYALKLNK
                     TNNFTSMHAKTTSDDYITNEVTAITNTSYANFWAVNNSKSKISNKYKQGVGTGSCNLIF
                     TKSGYNSTNTQVGMGMENYQSQLSTAFVSGNVDFR"
     CDS             complement(2889..4283)
                     /locus_tag="ctg13_73"
                     /transl_table=11
                     /translation="MAENIENNGCSQRDNAEHEGYVKASRSFNRIWKERDSAQPRLLET
                     ILYKDNFNRAYKRVKANKGAPGIDGMTIEEALPYLKEHQQEITDRIYRGKYTPSPVRRV
                     EIPKPDGGVRKLGIPTVIDRTLQQAITQQLVPIYEPLFADGSYGYRPNRSAKDAILKVK
                     EYAEQGYTFAVVLDLSKYFDTLNHEILINLLRKNVKDERVVQLIKRYLKSGVMENGVVI
                     DTEEGSPQGGNLSPLLANIYLNEFDQEYLKRGVPCIRYADDIVLLAKSKRASERLLESS
                     TKYLEERLKLTVNREKSRTVSVFAIRNFKFLGFALGRNGKGIYVRVHPKSWKKFKSRLK
                     ELSSRKRCQSIKPSLEKIKVYARGWLNYYGIASMKNNIDDINGWLYHRIRMCIWKQWKK
                     PRTKYKNLVKLGIPEHYASTIANSRRKYWYISNNKAVIWALNKERLINSGFYDLATAYQ
                     SVHVNY"
     CDS             complement(4794..5465)
                     /locus_tag="ctg13_74"
                     /transl_table=11
                     /translation="MKKSSIYGILSIVLIVGMFFTGCASKNNASQLNTNVSNLPIHQMH
                     ASFVYDTDNIREAVGICDYVFVAKVVSCDGTEYRNVITTEDEKGNPKEVGSPYTNYTIQ
                     VLENIKGELITDKPIPIVKQGGISEKQDAIYLFENDSLPSENSIYIFLAYAQEDGSLLI
                     SGPNSNVMCNDSNMYSINSVSEEKSVTEYDEFITYKDANDNEIIPVDRERYKSIYETDN
                     N"
     CDS             complement(5481..6002)
                     /locus_tag="ctg13_75"
                     /transl_table=11
                     /translation="MHFKKSVLKNHLLYSIITLMAIAMLFPITAFAQAYVQTWDLVDSG
                     KHLDYDGNSTYMSYINTGAATWNAYKSGVIRKDSAFVVEDVYVSDVNASNGWAGMTYSS
                     GKIELNTYYMSGYSNSKKQNVATHELGHALGLDHSTSTDVMDAAITGHTSTQALSQNDK
                     DSYDAAYNNY"
     CDS             complement(6319..7572)
                     /locus_tag="ctg13_76"
                     /transl_table=11
                     /translation="MVNFTSNTYQMKREILSFSNKISKKLPKPERKFIADMNYGILASR
                     SCLLTDIVDQLHEPSRKINIVDRLSRHLAKGTSKDALKAYLALVKKWCPDQPVIHIDDS
                     DVVKPDGYKFESLGLVRDGSASTAAKNVFKKGYHVTEATVLTAANHPVSIFSEIHSSKE
                     KDFTSINDVTFSAMERAAALFKKAAFVMDRGYDDNKMFLKLDSMGQDYIIRLTAKRKLL
                     YHNKWVFATELRNRRKGKVKLPLFYKGKMHDAYLSHVKVQITASRKDIYLVLVYGITEH
                     PMMLATNREIKSKDDVIKAAKLYFSRWKIEEYFRCKKQMFQFENFRVRKLKAINALNFY
                     LTLCMAFLAHISMKPETNALKVSIIQKADPVKEKVHFCYYRLAKGICGILSYAKEGVRL
                     WFRTKRPAYRQLCLKLTV"
     CDS             complement(7650..7853)
                     /locus_tag="ctg13_77"
                     /transl_table=11
                     /translation="MLPFVHSELPFMHRGIEKYKDFVIFKVYYYILSILRIYNMLEFPQ
                     FCPQNPQSDLLILHIFQKIPKI"
     CDS             7921..9273
                     /locus_tag="ctg13_78"
                     /transl_table=11
                     /translation="MLYIDSIWEYIVNFLELALFIIFIHKKLRIRANYKHQAVLMFLFV
                     SFQFAVLCTLNKMGISSYSTLMSSCVLDIGYAVLFYRDSIIRRIFWGFSYSIICLVAEQ
                     ISFFIPVTLYKGASLELLLGGTLRKPYTMLYLAMIAVFVLLFHSIGNKDISLSPFQKVA
                     YIFIAISGLAIGHYILRLTLESVDKFGDSSFSARLSLVDLFFIILFLVLMLYIYQLGYS
                     KEENIRLLEEQKIYELERTEFNSLSETTERLRKMKHDMQIYVDAINVLAKDKKWDELIA
                     YTEQYHNTLATTQSAIATGNIAIDCILTAKLDYAEKHGIKTEYSIMAPENFPLDSVELS
                     SILGNIWNNSIEAGERLIISDPTEHPYIYFYIKPYQNMILIHIENNYDGVIKGSIDGDI
                     LSVKQGKEHGLGIRRVKELVEKADGVLQITSDNKIFSVHIMIPDKENNKLL"
     CDS             9270..10004
                     /locus_tag="ctg13_79"
                     /transl_table=11
                     /translation="MKMKITILEDSVIESERLKNGIRKYGQQYDWDIEIDEYESGEEYF
                     SKNSEGTTIQASAFFLDIQMGQMNGIEVAKRLRESGYQGIIVFLTAFREYVFRGYEVRA
                     LNYLLKPVKENTLFLCLDEIAKELSNNTYIYRNKQEIVSIPYADILTFSSRLHYVDILT
                     VDGKCYEQMSTLNKIIVHLPSEFIRTHRSYIVNMAHIYRITSGTIELSNHLTTQIARSY
                     SKDVISAFAKYTTRFDTSGDFE"
     CDS             10001..10567
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg13_80"
                     /sec_met_domain="AgrB (E-value: 4.3e-30, bitscore: 96.9,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITKWATSIANKLAELSGEDVSADQLEIYIYGLECFLNTFITIVL
                     LFVWGVLSHTLGYTLIWVITFSLLRHYTGGAHAPTQLTCILGSFFLGCLDKWAIIYLKP
                     TVLGYLILVLMCILFAPISNHKICLTTKQKWIHKLISVIIVSIGFLLFYKIGNTKMNTT
                     LFYSFFCVIILMIVETIKNLMRHFK"
     CDS             complement(10642..12207)
                     /locus_tag="ctg13_81"
                     /transl_table=11
                     /translation="MPRNSFVQMSKLHNVRGRIYYISSDKKQENLYAVYETTDRKFWTE
                     LAKCNQAEFKKSGTEGKCIEAREFIIALPESFVDYPPDGLLKYMTDKFKSRYGVDCIAA
                     LHHNKRKTNYHIHLIFAERNYLDEPIEKIATRNMFYDEKGNHVRTKKEILDENGTIRKR
                     CKVIKKGEVYERQMFTIKDARFKQEHFLDEVKVFYTDVINGLVKDEKEKLSAFKRGDVY
                     LATKKIGKNNPKADKITLNNKVIQDWNRTVDHALVSGMERKEILKVKQEQISTPIKESI
                     HKYGNHPELLFMIIFRAIELLKELIKLLIQKQEQQKARISDLMERRNEKQEKQPAPSVT
                     QTDNQTIPAVTQPFKAPATTTAEKTVIPPRPRMSELAHDYEMRLEEIMEKLKRQNRAIH
                     TQEVKKDLIDEDLKNCTGLFQGKKRKELQAQSNKYAETIKIMKQGLSHIVQDYKYPTVD
                     AFLQVYKQGKSEYESYVKANKEWNSKYGENSIHRKLAEKQAEVQKREQDRDFNYRSPSD
                     RGAR"
     CDS             complement(13262..13495)
                     /locus_tag="ctg13_82"
                     /transl_table=11
                     /translation="MTELKFALSIEEAADYTGIGRNTLRNLVEWEKLPILRVGRKILIR
                     RERLDEFLILNEGKDLRDRHAVKAVKGTMKNE"
     CDS             13733..14356
                     /locus_tag="ctg13_83"
                     /transl_table=11
                     /translation="MLKDKELRKTIGSRAKSRRQELGLNQPYVAEKMGVTASTIQRYEA
                     GTIDNTKKMTLEGLADALHVSVEWLKGETDEYETDITDKRELQIRDVMTSILNKLPYDM
                     EQSESDFSKDLLLLMLREYELFVDSFQFACKNFKGNTDNKMLAQTMGFESNKEYNEIMF
                     LREITHTVNALNDMGDIVRLYSKNPETAKNRLANLLSEKDPDSV"
     CDS             14440..15738
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 159.3; E-value: 3e-48)"
                     /gene_kind="other"
                     /locus_tag="ctg13_84"
                     /transl_table=11
                     /translation="MAKGSVRKKGKKWYYRFYVEDASGNLVQKEFAGTESKSETEKMLR
                     KAMEDYDAKKFLAKADNLTLGQMLDVWAEEDLKTGSLSNGTVGNYLQAVNRIKQHPIGN
                     RKLKTVTSEHLQKFMDLLAFGGEEGNFKSKGYTIDYIRSFHAVLQQSFRFAVFPKQYIT
                     FNPMQYVVMRRKAEEDVDLFSDNDEDAEVINPITPEQYQTLMEYLEERNKPAVLPVQIA
                     YYTGLRLGEVCGLSWSDINFEEQYLTVRRSVRYNGARHKTEIGPTKRKKVRIVDFCDTL
                     ADILKKAKKEQRKQVFSYGELYQRNYYREVKEKNRIYYELYHLDGTEDIPLDYNEIDLV
                     CIRPDGAYEAPATVETALRTARKRLSELDDNFHFHTLRHTYTTNLLSNGAAPKDVQELL
                     GHSDVSTTMNVYAHANREGKRNSARLLDKVVGE"
     CDS             15897..16388
                     /locus_tag="ctg13_85"
                     /transl_table=11
                     /translation="MGRKEITTKEDLMKVIELFENTGITYWLDGGWGVDILAGKQTRIH
                     RDIDINFDAQHTEKLLNVLLNLGYKIDTDWKPVRIELYSDELGYLDIHPFVLNEDGTSK
                     QADLEGGWYEFEKDYFGSAFFEGKTIPCISLKGQRVFHSGYELRDKDKHDISILESLSK
                     "
     CDS             complement(16506..17312)
                     /locus_tag="ctg13_86"
                     /transl_table=11
                     /translation="MKGATSIQERLWELRKDKGLNLEELSELTGISKSALGSYEKEDYK
                     EINHGNLIALADFYGVSVDYLLCRTENREQINTPLTELHLNDEMVALLKSGRINNRLLC
                     ELATHKDFIKFLADIEIYVDGIATMQIQNLNALVDTVRHEIIERYRPGEDDPHLKVLQA
                     AHISDDEYFSHMVLDDLNRIIRDIREAHKKDSESAPQTTVADELKENLEAVENFKGSRD
                     EKLVVLYCKQLGINYKNLSDEEFRWLIRILKKSKKMGTPISQRKKR"
ORIGIN
        1 ttatttactt ttttctttga tttgggatca agaccaaagt atatcattat ttcatatatt
       61 tcttcatctg atacaattcc ttttatattg gaaagcattt tcaaattttc aaatcctgaa
      121 tacatactcc aaaaagaaat attttcaata acagctccta aatctggtaa aacatccata
      181 tctttatgta atgccttgtg attatatttt atgtatcctt tgtctgtatt tataaaacct
      241 gcaatggctc tgagtagcat tgttttacct gaaccatttt taccatatat tccatatatt
      301 ttaccagatt caaatgtata actgatatca tcaagcactt tttcaccttt aattgacttt
      361 gaaatagatt ttacatataa attcatggat atcattcacc tcacaatatt tgtttttttt
      421 cgcaaagaaa tttacctatc cacaccaaaa cagcggatga tataactgaa atgagacagc
      481 ttgacttaaa attcaataaa tctatattgc ttgtagtcca ttcgtaattt tcttcgacat
      541 aatatataat aagcttgtta tgccaattaa ataaaggaat atgtagcaag gaataatgcc
      601 aaattttcca tataacattt cccattgaaa aataaaatcc acacaccatt actggaataa
      661 aaaatacaat aaatgcaacg atgtatccta taattgaatc tttccaaaat gaaaacaaat
      721 aactaatcat ttgcaaatga aaaatctcta tcaatagcat aaaaataact ttgaaatctt
      781 ctaagccatt agaggtatgc tctacaaaaa gaaaaaacaa ataatcggaa acaactacaa
      841 tacagtcacg taatatcatt tttattaata tatccttata aattatgtgt tttttcccat
      901 aacgaggaag tagaattacc atgttatcat ttgcatcatt aaataagtcc attgtaagat
      961 aacaaatctc aaggataaac aaaatcgcaa aaaatgataa agatataagg tcaaacgaat
     1021 gatctattag tattccccca aaatatattt gtgaacgtac tccttctgtt attgtaacca
     1081 gactattatg aaaccccaag tacacattag cataaaaata tctaattaca aatgttataa
     1141 gtgatactag taagcatttt ccaacattaa cattcaaaat ttttttctta tataacttca
     1201 taatttttta tttttctctg tataatgcca atacttaatc caaaaataag caatatcaga
     1261 acaatttctc ctattatatt tccatgaaca ttaggcataa tataaccttg tatagagaat
     1321 tcatttagcc caaagacaga aacaatcaaa ttaaaaacaa tatagaatat aaacaaagca
     1381 ccaggtatct ttgcgaaata tagaactttc attttgttat aatatgaaag agcataagct
     1441 aagatagcta atcccgagcc aaaaattccg taattaaaaa tgtatattag attatataaa
     1501 gttggatgtt gcaatctcac catatcaaga aaattgtcag cgttatatga taccaaacct
     1561 atagcgtaat caggttctcc ccaagcactg tcatatccat gtattggata tgtcaagtgg
     1621 cataataata aatttatgag cattggtatt gttattgtca aaaaggttac aatcagaatg
     1681 ccaaataatt ttcctgctaa atatttcttt ttcccgattc tttgaataag taggattgaa
     1741 ctattgcttt tttcttctct tattaaggaa agtgatgcaa taattgttgc ataaacaggc
     1801 aataacagat acattatata tggaatatat gccgcttcag tgccctgtaa tacgaaattt
     1861 tcatttgctg aacgaataaa ttgataactt tttcctatat cattttttac acataaaata
     1921 tacgaagcaa tatttaaaat cattagagca ataaaaacaa ctttatattc tgcacgatca
     1981 atacaatgtt tgatttctat aagaaccatt tttttcataa tctttaccaa aagggcataa
     2041 acccacgaag aggtttatgc ccatcccttc tgttatctaa aatctacatt tccacttaca
     2101 aatgcagttg ataattgaga ttgataattt tccattccca taccgacctg tgtgttagta
     2161 gaattataac cgctcttggt aaagattaaa ttacaagatc ctgttccaac accctgctta
     2221 tacttattag atattttact cttgctgtta ttgacagccc agaaatttgc gtaagaggta
     2281 ttggtaattg ctgttacctc atttgtgatg taatcatcgg atgttgtttt tgcatgcata
     2341 gaggtaaagt tattagtctt attcagttta agtgcataag cggtgtaaga tgccgcctga
     2401 gaatatgctg ctgaagaaag aaatacacat cctgcacaaa acaaaccaat acctactttt
     2461 gcaatcttct gttttaaact ttttaacatc atagtcaatt cctcccaatc ttattttttt
     2521 aactgcgttg gtacttttgg ttcatacaac aaaccacggc acaatgaatt tgcattactt
     2581 cgagcaatag cagtcactgc ctgaagtacg agacgggcac ttttctgggg tgccttgttt
     2641 acttgcttat tgtccatcgt tttcaccccc ccccctcctt aattgtctga caattacaga
     2701 caactttatt tgtttaccat ggtatgtgct taatataaca gagtatttaa ttttttcaat
     2761 ccctctatgc acgaatggta gcccaacatg cacgaactgt tctacatata ggtataaatc
     2821 gagtaggagg cggtgactaa ccgccgtcct ctcacagcac cgtacgtacc gttcggtata
     2881 cggcgctttc aatagttaac gtgcacagac tgataggctg tggctaaatc ataaaagcca
     2941 ctgtttatca gtctttcttt attcagcgcc caaatcacag ctttgttatt gctgatatac
     3001 caatactttc tgcgactgtt tgctattgtt gacgcatagt gttctgggat tccaagtttg
     3061 actagatttt tatatttcgt tctaggtttc ttccactgtt tccatatgca catgcgtatt
     3121 ctgtgataga gccatccgtt gatatcatct atgttgttct tcatgcttgc aattccgtag
     3181 tagttaagcc atcctcttgc atatactttg attttctcaa ggcttggctt gattgactga
     3241 catcgcttac gggaagataa ctccttcagt ctggacttaa acttcttcca tgacttcgga
     3301 tgaactcgga catatatgcc ttttccgttc cttcccaatg caaagccaag gaatttaaaa
     3361 tttcggattg caaacacgct gactgtacgg ctcttttctc ggttgactgt aagtttcagc
     3421 ctctcctcaa gatattttgt actgctttcc aagagtctct ctgatgctcg cttgctcttt
     3481 gcaagaagca cgatgtcatc tgcatatctt atgcatggaa cacctctttt caggtattcc
     3541 tggtcgaact cattgaggta gatgtttgcc agcaatggtg atagatttcc accttgtggt
     3601 gagccttcct ctgtgtcaat gaccactccg ttttccatta caccgctttt cagatagcgc
     3661 tttatcaact gtactacacg ttcatctttt acattctttc gtagaagatt gatgagaatt
     3721 tcgtgattaa gagtatcgaa gtactttgac aagtcaagga ctacagcgaa tgtatagcct
     3781 tgttctgcat actccttaac cttaagtatt gcatcttttg cacttctgtt cggacgatag
     3841 ccatagctac catctgcaaa cagcggttca tagattggca ctaactgttg ggttattgcc
     3901 tgttgaagtg tacggtctat cactgttggt atgccaagct ttcgcacacc accatctggt
     3961 ttgggaattt caactcgtct tactggagac ggagtatact ttccacgata aatgcggtca
     4021 gttatctctt gttgatgttc ctttagatat ggaagagcct cttcaatggt catgccatca
     4081 attcccggcg ctcccttgtt tgccttaact ctcttatacg ctctgttaaa gttgtcttta
     4141 tacagtatcg tttccaaaag tctcggctgt gcactgtctc tttctttcca tatccgattg
     4201 aatgacctag acgctttcac atacccttca tgttccgcat tatctctttg cgaacagcca
     4261 ttgttttcaa tgttttctgc catagacggt cattcctcct ttctcggtca tactcaagac
     4321 tcctactgat tcggtccttc acctctcggc tactatgacc tctgctgact tctatgcgtt
     4381 cagcattgct ttatgcaatg gttacctctt tcaaggcata ccgcacagac ctccctaggt
     4441 accacacgtt tcttcctctc catccatctg cctcatttat catgcatgat tccgtgtagt
     4501 tattgggctt taacatgggt tgctgtctta cccacatgca tgacctcata tgagatttct
     4561 gttcgtcaga ccagagattt gcccgtgagt tggtatattc ctcacatcca gcttccttca
     4621 gattccatct cacgatggac acccttgcct tcggctatat ccttcccact accgggcgga
     4681 ttcgggactt taacccgtta gaaacgtgcg ccgctaggcg cacaaccgaa aagatggcag
     4741 ataggttaag cacctacctg ccatctttaa tctatatatt tcagaaataa tgattaatta
     4801 ttgtcagtct catatataga tttataacgc tctcgatcaa ctggaataat ctcattatca
     4861 ttagcatctt tatatgtaat aaactcatcg tattctgtaa ctgatttttc ctctgagaca
     4921 gaattaatag aatacatatt cgaatcgtta cacattacat ttgaatttgg accagaaatt
     4981 agtaacgaac catcctcttg tgcatatgcc aaaaagatat aaatggaatt ttcggaaggc
     5041 agtgaatcat tctcaaacag ataaatagca tcttgttttt ctgaaattcc gccttgttta
     5101 acaataggaa taggtttatc tgtaataagt tcacctttta tattttcgag aacctgaata
     5161 gtataattag tgtaaggcga accgacctcc ttaggatttc ctttttcatc ttcagtcgtt
     5221 ataacatttc gatactcggt tccatcgcaa ctgacaacct ttgctacaaa tacgtaatca
     5281 cagataccaa cagcttcgcg aatgttatca gtatcatata caaaagatgc gtgcatctgg
     5341 tggattggca agttagatac atttgtattc agttgacttg cattattttt ggatgcacat
     5401 cctgtaaaaa acattcctac gataagaaca atagacaaaa taccatagat acttgatttt
     5461 ttcatagcgt tctccctccc ctaataatta ttatatgcgg catcatatga atctttatca
     5521 ttttgagata atgcctgcgt actagtatgt cccgtaattg ctgcatccat aacatctgtt
     5581 gaagtactgt gatccaaccc taatgcatgt cccaattcat gtgtcgctac attctgtttt
     5641 ttactattac tataaccgct catataatag gtattgagtt caattttacc actagaatat
     5701 gtcatgcctg cccatccatt cgaagcattg acatcgctta cgtatacatc ttctacaaca
     5761 aaagcactgt cttttctgat tactccagat ttatatgcat tccatgtggc agccccagtg
     5821 ttaatataac tcatgtaagt gctgtttccg tcatagtcta gatgtttgcc agaatcaaca
     5881 agatcccatg tttgtacata agcttgtgca aatgccgtaa taggaaatag cattgctata
     5941 gccattaaag ttataatgct atacaataaa tgatttttta aaacagattt tttaaaatgc
     6001 atactccttc actccttttc aatcatgtaa caacggttat cttcaattat tcttaaaggt
     6061 tatctttatg aaaattgaaa cgcaacacat actagtacac attatatatc ctgttaatat
     6121 tcctaaagta cgacatctta tcatctccac tccatattat cttgagtttc cgcaaattgc
     6181 aatagaaaga tagatatgtt tttccaaagt accaatctgc cgattttttg agaaattcag
     6241 agtggcagta ctgagagtag aggcacttta ataagccccg ccggaaccgg actttgggag
     6301 acatattctt ttatctattc aaacagtcag cttaaggcag agttgacggt atgccggacg
     6361 tttggtccgg aaccacagcc tgacgccttc ttttgcatac gacagtatgc cgcagatgcc
     6421 ttttgccagc cggtaatagc agaaatgtac tttttccttt acaggatctg ctttttgtat
     6481 gatggaaacc ttaagggcat ttgtttccgg cttcatggag atatgtgcca gaaacgccat
     6541 gcataaggta agataaaaat ttaacgcatt gatcgctttc agcttcctta cccgaaagtt
     6601 ttcaaactgg aacatctgct ttttgcagcg gaaatattct tcgattttcc atctggaaaa
     6661 ataaagtttt gcagccttta tcacatcgtc tttggatttg atttccctgt ttgttgcaag
     6721 catcatggga tgttccgtaa tcccatagac gaggacgaga taaatatctt ttcgcgaagc
     6781 agtgatctgt acttttacat gggaaagata ggcatcatgc attttgcctt tgtaaaacag
     6841 tggtaatttt actttgcctt tcctgcggtt acgcagttcc gtggcaaata cccatttgtt
     6901 gtggtataga agcttacgct ttgcggtcag acggatgata taatcctgtc ccatggaatc
     6961 cagtttcaga aacatcttgt tatcatcata gccccggtcc atgacaaagg ctgctttttt
     7021 gaataaagcg gcagcccgtt ccatagcaga gaaagttaca tcattgatgg aagtaaagtc
     7081 cttctctttt gaagaatgga tctctgaaaa gatactgacc ggatgattag cggctgtaag
     7141 tacagtcgct tctgttacat gatatccctt tttaaataca ttctttgccg cagtgctcgc
     7201 tgagccatcg cgaaccaggc cgagggattc aaatttgtaa ccgtcaggtt ttacaacatc
     7261 gctgtcatca atatggatga ccggctgatc ggggcaccat tttttcacca gagccagata
     7321 agctttcagg gcatctttcg aagttccttt agcgagatgc ctggaaagac ggtcaacgat
     7381 gttgatcttt ctggaaggtt catgcagctg gtcaacgata tcggtgagca ggcagctgcg
     7441 ggaggcgaga atgccataat tcatgtcggc gatgaacttt ctttcgggtt tcggcagctt
     7501 tttggaaatt ttattggaaa aagataaaat ttcccgtttc atttgataag tatttgaggt
     7561 aaaattaacc acagggaatc ctccttcttt ttgtttagta cgattttttt gtggtgatta
     7621 aattttacat caaaaaggga gaggattcct tatatttttg gtattttttg aaagatgtgt
     7681 aaaatcagta agtctgattg gggattctgt ggacagaact gcggaaactc aagcatatta
     7741 tagattctca gaatacttaa gatgtagtag tataccttga atataacaaa atctttatac
     7801 ttttcaatac ctctatgcat gaatggtagc tcactatgca caaacggtag catattatgt
     7861 tgtgtaccta ctttattgat gataaaatat gacggagaat gattaaagga agtggtagct
     7921 atgctatata ttgactcaat atgggaatat attgttaatt tcttagaact ggcattgttt
     7981 ataatattta tccataaaaa attgcgtatt cgagcaaatt ataaacatca agcagttttg
     8041 atgtttcttt tcgtatcatt tcagtttgct gtgttatgca cgctgaataa aatgggaata
     8101 tcatcctaca gcactttgat gtcatcttgt gttttggaca ttggatatgc agtattgttc
     8161 tatcgtgata gtataattcg ccgtatcttt tggggctttt cgtattccat catttgctta
     8221 gttgcagaac agatttcgtt ctttattccc gttactcttt ataaaggagc gtctctggag
     8281 ctattattag gtggaacatt acggaagcca tataccatgt tatatttggc aatgatagct
     8341 gtttttgtct tgttatttca ttctattgga aacaaagaca tatctctttc accgttccaa
     8401 aaagttgcat atattttcat cgcaatttct ggacttgcaa tcgggcacta catattaagg
     8461 ctgactttgg aatctgttga taaatttggt gattcatcct tttcagctag gctatcattg
     8521 gttgacttgt tttttattat tttattttta gtattgatgc tatacatata ccagctaggt
     8581 tattcaaaag aagaaaacat acgattactg gaagaacaaa agatttatga gctggaaagg
     8641 actgagttca atagcttatc tgagacaact gaacgattac gaaaaatgaa acatgatatg
     8701 cagatttatg tggatgcaat caacgtatta gcaaaagaca agaaatggga tgaacttata
     8761 gcatatacag agcaatacca taacactctt gcaactacgc aaagtgccat agcaacggga
     8821 aatattgcta ttgactgcat acttaccgca aaacttgatt atgctgaaaa acacggaatt
     8881 aagacagaat attctattat ggctcctgaa aattttccgc ttgattctgt tgagctttca
     8941 tccatacttg gaaatatatg gaataattcc attgaagcag gagaaagact tataatctct
     9001 gatccaaccg agcatccata catttatttt tatattaaac cttaccagaa tatgatactg
     9061 attcacattg aaaataatta tgatggtgtg ataaaaggta gcattgatgg agacattttg
     9121 agtgttaaac aaggaaaaga acatggactt gggataagac gagtaaaaga gcttgtagaa
     9181 aaggcagatg gcgtattgca gattacatct gataacaaaa ttttttccgt acatattatg
     9241 ataccggata aggagaataa caaactacta tgaaaatgaa aataaccata cttgaagatt
     9301 ctgtgatcga atcagaacgg ctgaaaaatg gaataagaaa atacgggcag caatatgatt
     9361 gggatattga aattgacgaa tacgaatcgg gcgaagaata tttttcaaaa aattctgaag
     9421 gcacaactat acaggcttca gcatttttcc ttgacataca aatggggcaa atgaatggaa
     9481 ttgaggttgc taaacgcctt cgtgaatctg gttatcaagg tattattgta tttttaacag
     9541 cttttagaga atatgtattc cgaggatatg aagtcagagc tttaaactac ttgctaaaac
     9601 ccgtcaagga aaatactctt tttctgtgtt tggatgaaat cgcgaaggag ttatctaata
     9661 atacctacat ataccgaaac aagcaggaaa ttgtaagtat tccctatgca gatatattga
     9721 cattttcgag cagattacat tatgtggata tattgaccgt agacggcaaa tgctatgaac
     9781 aaatgtctac cctaaataag attattgtcc atttgccaag tgaatttatc cgaacccatc
     9841 gttcttatat tgtaaatatg gcacatatct atcgtattac atcaggaacg attgaattgt
     9901 caaatcatct aactacacaa atcgcacgtt cttattccaa agacgtgata agtgcttttg
     9961 ccaaatatac aacaagattt gatacaagcg gggattttga atgattacga agtgggctac
    10021 atctattgct aataagttag cagaactatc cggggaggat gtttctgcgg atcaattaga
    10081 aatatacata tatggcttag aatgtttttt gaatactttt ataaccatag tgttattgtt
    10141 cgtatgggga gttttatcac atacactcgg ctatacccta atttgggtaa ttaccttttc
    10201 attgttacga cattataccg gaggtgccca tgctccaacg cagttaacat gtatcttagg
    10261 cagctttttt ctcggttgtc ttgataagtg ggctataatc tatttaaagc caactgtact
    10321 aggatatttg atacttgtcc ttatgtgtat attatttgca cctataagta accataaaat
    10381 atgtttaacc accaaacaaa aatggataca taaacttatt tctgtgataa ttgttagcat
    10441 tggatttctg ctgttttata aaattggaaa cacgaagatg aataccacat tgttttattc
    10501 ctttttctgc gtaatcattc ttatgatagt cgaaacaatt aaaaatctaa tgagacactt
    10561 taaatagcag gatgactttt cataaatatt caaaaaagat aaagaatttg atggtcttta
    10621 tcttttttga atttaattag attatctagc tcctctgtct gatggcgaac gatagttaaa
    10681 atctctgtcc tgttcccgtt tctgaacttc tgcctgtttt tctgccagct ttcgatggat
    10741 tgagttttct ccatacttgg agttccattc cttgtttgct ttgacatagg attcatactc
    10801 ggacttgcct tgtttataga cttgcaggaa cgcatctacc gttggatatt tgtaatcctg
    10861 cacgatatgg gataatccct gcttcataat cttaatcgtt tctgcgtatt tgttagactg
    10921 tgcctgcaat tcctttcgtt tctttccttg gaataatcct gtacagttct tcaaatcctc
    10981 gtcaataagg tcttttttca cttcctgcgt atgaatggct ctgttttgtc gtttaagttt
    11041 ctccataatc tcttcaagtc gcatctcata atcgtgtgcc agctcagaca ttcttggtct
    11101 tggcggaata acggtctttt ctgcggtagt agtagcaggt gctttgaatg gttgggtcac
    11161 agcaggaatt gtctgattgt ctgtctgtgt aacggatgga gctggttgtt tctcttgttt
    11221 ttcatttctt cgctccataa ggtcggagat tctggctttc tgttgttcct gtttctgtat
    11281 cagcaacttt atgagttctt ttaacagctc gattgcccga aagataatca taaacaaaag
    11341 ctccggatga ttgccatact tgtgaatgga ttccttaatc ggagttgaaa tctgttcctg
    11401 ctttaccttt aagatttcct ttcgctccat ccccgatacc aaagcgtgat ccacagtacg
    11461 attccagtcc tgtatgacct tattattgag tgtaatctta tctgcctttg gattgttctt
    11521 accgattttc ttagtggcaa gatagacatc cccacgcttg aatgcagaca gcttttcttt
    11581 ctcatctttg acaagtccgt tgatgacatc ggtataaaat accttgacct catctaagaa
    11641 atgttcctgc ttaaagcgag cgtccttgat ggtaaacatc tgtctttcgt agacctcacc
    11701 tttcttgatc accttacacc ttttacggat agttccattc tcgtctagga tttctttctt
    11761 ggtacgaaca tgattacctt tctcatcata gaacatattt ctggtggcaa tcttttctat
    11821 cggttcgtca agataatttc gttctgcaaa gataagatgg atatgataat tcgtctttcg
    11881 tttgttatga tggagtgctg caatacaatc aacaccatac cgacttttga atttatccgt
    11941 catatatttt aatagtccgt ctggcggata atccacaaag gattccggca gggcaatgat
    12001 aaattctctt gcttcgatac attttccctc tgtaccgctt ttcttaaatt ctgcctgatt
    12061 gcacttggca agttctgtcc aaaattttcg gtctgtggtt tcatataccg catagagatt
    12121 ttcctgtttt ttgtcactgg agatataata gattcttcca cgaacattat ggagctttga
    12181 catctgcaca aatgaatttc ttggcatagc gatttcctcc tttcccagtt ttgattttgg
    12241 aaaagaggac agataagata gatgagatgt gagtagtaaa ctttccctgt gagcgagtgc
    12301 ataggcactc gtcttgcgaa cacatccgcc ttgtggcggc taagcctcgc agagcgaaat
    12361 acacagagta caaaacgaag ttttgtgcga tgggtgtatt tcgctctcaa acgccgaggg
    12421 cttgcttatg aagttcactt ttagctgtaa ctgttccctc agcacctaat tttgtgcctt
    12481 taatggcaca ctttttatgt gccgtatccg gcactccctt ttcttaacag aaatgctaga
    12541 agattgctat gaaaatcagc gaaacaatag acgaatccgt tagcactttt gccttaacaa
    12601 tagcattgtt ctattattca gactttttag caaaaaccgt agaaacagta gaagtctgct
    12661 attaaaatcg aaaaaacaat agcacgattc gttagcattt ttgccctgac aatagcattg
    12721 tgttacttcg cttactttta aactgtgtct ggcaaggaag tggtagtaaa agttcctatt
    12781 aaatttcatt tttaatagtg cattgtttta ttacattttg attttaatag agctttttac
    12841 tattaactct ttgaaaatgt accccataga ttggacactc aaaatcatag tagcgtacac
    12901 tttttgtcat aggtcggaca gcttttttca tagctacact tggtatgact tctcacagca
    12961 ctttttgtaa gttgggtgga cttgtcctac cagtcggctt cacttgggtg gatggttgca
    13021 cccacttcat tttctggctt gggtggacta ttcataacac cttttgcatc ttgggtggac
    13081 ttgtcctacc aacaagctat aactgggtgg acgattgcac ccattcacat ccatcttgtc
    13141 ctcattttcc aaaagttctg gttgtatctg aggacttgtc cgtgatataa tctatttgcg
    13201 tgtaggtata tcatggcttt tagtcagata cataccagag ggatggtctt aggactgtcc
    13261 cttattcatt tttcattgtt cccttgaccg cttttactgc gtgtctgtct cgtaaatcct
    13321 tcccctcatt gagaatcaga aactcgtcta atcgttccct gcggattaag atttttcttc
    13381 ccactctaag gataggcagc ttttcccatt ccacaagatt tctaagagtg tttcttccga
    13441 tacctgtata gtcggcagct tcttcaatgg agagagcaaa ctttaattct gtcattcgat
    13501 cacctcattc ctgcgtagga ttacaagtct tgtatatcag aggatgttcc tttttgaaga
    13561 aaggattagc cttttttaaa acttgcgtta cgcaattctg attaaagtat atatctttta
    13621 taacgctatg tcaagcctta cgaaattcta tcatctttta tagaattgcg tattgcaata
    13681 tatcgtgtta tgtggtatag taatgacata ccgaaaaagg aggttcgcaa gtatgttaaa
    13741 agataaagaa ttgcgaaaga caatcggtag cagagcaaaa agccgtagac aggagttagg
    13801 attgaaccag ccttatgtcg ctgaaaaaat gggcgtgaca gcctcaacca ttcagagata
    13861 cgaagcagga acgattgata acaccaagaa aatgacctta gaaggtctgg cagatgcact
    13921 tcatgtatct gtggaatggc tgaaaggtga gacggacgaa tacgaaacag acattacgga
    13981 taaaagagaa ttacagattc gtgatgtgat gacttccatt ctgaataagc tcccttatga
    14041 tatggaacag tccgaaagtg atttttccaa agacctgcta ctactgatgt tacgggaata
    14101 cgagctgttc gtggattcgt tccagttcgc ttgtaagaat ttcaaaggaa atacagataa
    14161 caaaatgctc gcccagacaa tggggtttga atccaataag gaatacaatg agattatgtt
    14221 ccttagagaa atcacccaca ccgtcaacgc attgaacgat atgggcgata ttgtaagact
    14281 gtattctaag aatcctgaga cagcgaaaaa tcgactagcc aatcttttat cagaaaaaga
    14341 tcccgattcg gtatagatag gcagacggag ctatgatata cttacacgca agaagcattt
    14401 caccagttcc gattgccgat atcgaaagga gaaacgatta tggcaaaagg ttctgtaagg
    14461 aagaaaggca agaaatggta ctaccgcttt tatgtggagg atgcaagtgg taacttggtt
    14521 cagaaagaat ttgcaggtac ggagagcaaa tcagagacag agaaaatgtt acgcaaggct
    14581 atggaggatt atgacgcaaa gaaatttcta gccaaagcgg acaacctcac actcggacag
    14641 atgctagatg tatgggcaga ggaagatttg aaaacgggtt cacttagcaa cggtacagtc
    14701 ggtaactatt tacaggcagt aaacaggatt aaacaacacc caatcggaaa cagaaaacta
    14761 aagacagtca cttcggagca tttgcagaag tttatggatt tacttgcatt tggcggtgag
    14821 gaaggaaatt ttaagtcaaa gggttacacc atcgactata tccgttcttt ccacgcagtc
    14881 ctgcaacagt ccttccgatt tgcagtcttt ccaaagcagt acatcacatt caatccaatg
    14941 cagtatgtgg taatgcgtag gaaagccgag gaagatgtgg atttgttttc tgataatgat
    15001 gaggatgcag aggttatcaa cccgattaca ccagagcagt atcaaacgct tatggagtat
    15061 ctggaagaaa gaaacaagcc tgctgtcctg ccggtacaga tagcgtacta cacaggtctt
    15121 agacttggag aggtatgcgg actgtcttgg agtgacatta actttgagga acagtatctg
    15181 acagtacgaa gaagtgtccg ttacaacgga gcaaggcaca agaccgagat tggtccgaca
    15241 aagcgaaaga aagtccgtat cgtggatttc tgtgatacgc tcgctgacat cttaaagaaa
    15301 gcgaaaaagg aacagagaaa gcaggtattc agttacggag aactctatca gaggaactac
    15361 tacagggaag ttaaggaaaa gaatcgtatc tactatgagc tttatcattt ggatggcaca
    15421 gaggacattc cgcttgatta caacgagatt gaccttgtat gtatcagacc ggacggagca
    15481 tacgaagccc ctgcaacggt tgagacagct ttaaggacag caaggaaacg attgtcggag
    15541 cttgatgata atttccactt ccacaccctg cgacacactt ataccacaaa cctgctctca
    15601 aatggagcag caccaaagga tgtacaggaa ttacttggac actcggatgt aagtaccact
    15661 atgaatgtct atgcacacgc taaccgagaa ggtaagcgaa actcagcccg actacttgat
    15721 aaggtggttg gagaataaaa tcgaataaga aaaactttcc cttgtagata cctcataagg
    15781 gcaaaaacaa gggaaaagga tacatataga gtggcaaggc ataccgccaa gtcgcataaa
    15841 ataaggaaag ttgagatttt agttatacaa attagaagtt gtaaaggaga ctttgtatgg
    15901 gtagaaaaga aataacaaca aaagaagatt taatgaaagt aatagaatta ttcgaaaata
    15961 ctggaattac atactggttg gatggcggat ggggtgtaga tattttagct ggtaaacaaa
    16021 caagaattca tagagatata gatataaatt ttgatgctca acatacggaa aaattgttaa
    16081 atgtgctttt gaatctgggc tataaaattg atacagactg gaaaccggtt agaatagagt
    16141 tatatagtga tgaacttggt tacttagaca ttcacccgtt cgttttaaat gaggacggaa
    16201 cttcaaaaca agctgattta gagggtggct ggtatgagtt tgaaaaagat tactttggta
    16261 gtgctttttt tgaaggaaaa acaattcctt gtatatcctt aaaaggtcaa agagttttcc
    16321 actcaggtta tgaattaaga gataaagata agcatgatat ttcaattctt gaaagtttat
    16381 caaaataaca ttgctgtaat ttctaagata aattccactt tatcgctttg aaattttaac
    16441 tgaataacca cagcacaaac cgctgctaca tgggagccaa caaaccatgc aacagcggtt
    16501 tttccttacc tttttttcct ctggctgata ggcgttccca ttttctttga ttttttgaga
    16561 atccgaatca gccagcgaaa ttcttcgtct gacagatttt tatagttgat gccgagctgc
    16621 ttgcagtaaa ggacaaccaa cttttcatcc cggctgccct tgaaattttc gaccgcttcc
    16681 agattttctt tcagttcatc ggcaacagtg gtctggggcg cactctcact gtcctttttg
    16741 tgggcttccc gaatatcacg gataatccgg ttgaggtcat ccagaaccat gtggctgaaa
    16801 tactcatcat cgctgatatg ggcagcttgc agcaccttca aatgcgggtc atcttcgccg
    16861 gggcgatacc gttcaatgat ttcatgccgg acggtatcga caagggcgtt gaggttttga
    16921 atctgcatgg tggcaatccc gtccacataa atctcaatat ctgcaagaaa cttgataaaa
    16981 tctttatgtg tggcaagctc acagagcaga cggttgttaa tccgaccgct tttcagaagt
    17041 gcgaccatct catcattcaa atgcagctcc gtcaatggcg tgttgatctg ctccctgttc
    17101 tctgtccggc acagcagata atcaacggaa actccataga agtctgccag cgcgataagg
    17161 ttgccatgat tgatttcctt ataatcctct ttttcataac ttccaagagc tgatttggaa
    17221 atacccgtca actctgataa ttcttccaga tttaagcctt tgtccttgcg gagttcccaa
    17281 aggcgttcct gtatgcttgt cgctcctttc atgggcacac gctcctttcc ggcggtttga
    17341 ttgctgccgc ttaactggat tatatcacac tttccgcaat cgtggaaatt tctgattttt
    17401 acccttaatt cctactttgt ggacatacgg cacagggtac aaaaatgttc tatgatacag
    17461 gtagttcatc gatggattat tccaatcgaa tgaccagcct gtgtgggata tgctt
//
