LOCUS       c00043_gnlPro..        22128 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LEDLNGCF_43.
ACCESSION   c00043_gnlPro..
VERSION     c00043_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 05:21:11
            Original ID  :: gnl|Prokka|LEDLNGCF_43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 22128
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22128
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3344:12128]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3345..12128
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..22128
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..22128
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..95
                     /locus_tag="ctg43_1"
                     /transl_table=11
                     /translation="PVKSAFFHGRSSYNLYGLYLYAPVRRIEAN"
     CDS             375..1640
                     /locus_tag="ctg43_2"
                     /transl_table=11
                     /translation="LARNDGIDRTSVRNLAVSDKAVSNTQQHNEREKDSYRNPDIIPQR
                     VAWNVHFKKPTASYTDLFAQLEAAGTISTRGLKPDATHYCELVFDVNSAYFDNHGGYEF
                     AKQFYADAYKAAVQIVGGEQYILLAVMHADEINRAMTEALGREVYHYHLHVVYVPVVEK
                     QILWSKRCKDKALVGTVKETVMQVSRSKKWASKPLLDDAGKPVLQKNGKPVLKKSYSVL
                     QDDFFNYMRTAGYTDIERGERGSTEEHLTVTQFKVQREQERLDTLTTQADQQAQSLAKT
                     SQTLSKKEKELAAVQKKTTLTKEALIHARDLDYLGKRTFLGNYSLTEEEFSKLKKQADH
                     GYMMDVENRRLKEELSAAKKETARWSSKYHDLWYDVKPYLDALHRAPELVRGFLEKILA
                     PKQERTINVPQKNRKRGQDMEL"
     CDS             complement(1933..2184)
                     /locus_tag="ctg43_3"
                     /transl_table=11
                     /translation="MKYDARACHFNMDTGCVELRLRDGRKISIDCTGVEDALDVTMAQQ
                     TELDYLIYNDPLGYADLILNGDPEEYLKNTTGSHGLED"
     CDS             2627..3298
                     /locus_tag="ctg43_4"
                     /transl_table=11
                     /translation="MESTISAAPQISIDREKTLRNHRRYWVLRRAQDIVFSLLALILLA
                     PLALLISLAIVLDSPGDGAIFRQRRVGRDGKLFWLYKFRTMCPDAEEQLNELLSQNQMD
                     GPVFKIKGDPRITRVGRFLRKTSLDELPQLLNVLQGDMSIVGPRPALPREVELYSDYQR
                     QRLYVTPGLSCYWQIAPHRNEMSFDEWVALDMKYIQERSFWVDWKIIFLTVRAMLMKYG
                     E"
     CDS             complement(3345..5003)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_5"
                     /sec_met_domain="ILVD_EDD (E-value: 3.5e-223, bitscore:
                     732.8, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDNVTKGSERAPNRSLFYALGYTPEELERPLIGVVSAHSEIVP
                     GHMNLDKIADAVKAGVQMAGGTPILIPAIGVCDGIAMGHVGMKYSLASRELICDSVETM
                     LMAHQLDGLVLVPNCDKIVPGMVMAAVRMDVPAVVCSGGPMLAGTYGGEEVSLSKMFEA
                     VGAYKAGMITDEQLEDCTCNCCPSCGSCSGMYTANSMNCLCEAIGIALPGNGTIPAVYS
                     KRLQLAKHAGMAVMEMVRKGITARQIINERSIRNALTCDMALGCSTNTVLHLLAIAYEA
                     GVPIDLKLFNEISAKTPNLCHLAPAGPTHMPDLYAAGGIPAVQAELAKKGLLDLDVPTV
                     TGKTLGENIKGAHILNEKAIRPIENPYSQTGGLQILWGNIAPDGCVVKRSAVAPEMQQH
                     SGPARVFNSEEEAIAAIYAGKIVPGDVVVIRYEGPKGGPGMREMLNPTSALAGMKLDKT
                     VALITDGRFSGASRGAAIGHVSPEAASGGPIGLIEEGDTISIDIPNASITLEVSDAVLA
                     ERKAKYVAPEPNIKTGWLSRYARMVTSANLGAVLK"
     CDS             complement(5169..6188)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_6"
                     /sec_met_domain="IlvN (E-value: 1.6e-74, bitscore: 240.0,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.3e-65, bitscore: 210.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIKKYYDSDCNLGVLDGKTVAVIGFGSQGHAHSENLAESGVNVV
                     VGLRKGSAHWAKASEFAATHDNFKVMEVEEAAKAGDVVMMLVPDELCADIYNTQVAPYM
                     TEGKALAFAHGFNIHFKTITAPKNVDVIMIAPKGPGHIVRRLYTEGEGCPSLICVEQDY
                     TGKAKDIALAYASGIGAGRAGILQTTFKEETETDLFGEQAVLCGGVSELIHAGFDTLVE
                     AGYEPEMAYFETCHEMKLIVDLINEGGFSKMRYSISNTAEYGDYRTGKRLITEETRKEM
                     KKVLTEIQDGTFASEFLTEMSPKGGRKVHFLAKRRMEAELPIEKVGAELRSMMSWLKK"
     CDS             complement(6287..6850)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_7"
                     /sec_met_domain="ALS_ss_C (E-value: 4e-28, bitscore: 88.6,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSDQRRVISLLVDNQSGVLARVSSLFCRRGFNIDSLTVSATNDP
                     AVSRITVTITSDEKALQQLVLQTERLEVTRQVFVLDSEKALERELLLLKVESDVHNRTE
                     LREIACIYKAKIIDLSPDSMVFELIGRPDKLDAFLKMFEGYNILEQCRTGVTALERGGM
                     HQHIQKPPQEVRSVQLPPPGARRA"
     CDS             complement(6866..8530)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_8"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.3e-51, bitscore:
                     163.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLNGSQIFVEVLCEQGVDTLFGYPGGAVLNLYDELYKNADRITH
                     VLTAHEQGAAHAADGYARATGRTGVVLATSGPGATNLVTGIATAYMDSVPMVAFTGNVP
                     TSSIGKDGFQEAYIEGITVPITKHNFTVRRVEDLADTMRAAFRIAQSGRKGPVLVDIPK
                     DVTAAVCEFTPKQPEPIRTVTTYNEEQVHWAADLINAAQRPLVYFGGGVRSAASCQPLR
                     DLLHKAEIPATYTLMAAGVVPYGDPMNLGMLGMHGCYTSNRAVAECDVLIAVGTRFSDR
                     VALNPKTFAKNATIIQIDIDASELGKNVDVDLSIVGDAAYVLNAMLPQIKPAKHPEWMK
                     MIQSWQAQDYHPVSDPTRLMPHQVIGEVCNQCGPDAVYVTDVGQHQMWAAQYLRHTKSR
                     GFITSGGLGTMGFGYGAAIGAQMALGRQQRVVMFTGDASFHMNLNEACTAVSYELPIIT
                     VIFNNSVLGMVRQWQTSFYGKRYSQTDPHRKTDFVKLADGFGLKGYRCTNLPEFQEAFA
                     DALQQKGPTWIECIIDKDEKVLPMIPGGGDINDIIME"
     CDS             9098..10273
                     /locus_tag="ctg43_9"
                     /transl_table=11
                     /translation="VFRALLNDPVVAKLLDLTDRMEAGSTSYGPVCDAVAAFEAALFEY
                     TTNWGSYLSNAVLEAETICVRQAAAGQLDALLQSALDSELQFLQQLCGLTLDELFQTAY
                     SEQAQRPELAFLPRWQTCELDLAAAYAQRMSEVGKKGYGMFAKHHVFTVENGQLVPVKY
                     PDPQRLSELPGYEKEREKVIANTKALLAGMPANNVLLYGDAGTGKSSAVKAIANEFAPE
                     GLRLVEVKKNQLYQIPDLMDKLAANPLKFILFIDDLSFTANDDNFAALKAILEGSVGGR
                     AQNIAVYATSNRRHLIKETLSDRTGDDIHEADTRQELMSLSARFGLTVTFQRPEKARFE
                     TILEELAKQHNIQMPTEQLLLKAEAFALRAGGRSPRVAKQFIEQCEAGVQK"
     CDS             complement(10361..10735)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Ribonuc_L-PSP"
                     /gene_functions="regulatory (smcogs)
                     SMCOG1038:Endoribonuclease L-PSP (Score: 149.8; E-value:
                     1.2e-46)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg43_10"
                     /sec_met_domain="Ribonuc_L-PSP (E-value: 5.8e-47, bitscore:
                     149.8, seeds: 29, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVVSTANAPAAIGPYSQALDLGNMVFVSGQLPVDPATGTMADTV
                     EQQAAQSLANLKAILAEAGLSMNNVVKTVIFLADINDFAAVNAEYAKAFAEPFPARSCV
                     QVAAIPKGAKLEIECIAVRD"
     CDS             complement(10923..12128)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_11"
                     /sec_met_domain="PALP (E-value: 8.9e-94, bitscore: 305.1,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTLDKIYHAAFVLKDVARKTDLIEAPKLSKDCQLYLKTENLQAT
                     GSFKVRGAYYKISQLSEEESAKGVIACSAGNHAQGVALAATRRGIRSIVCMPDGAPLMK
                     VENTKNLGAEVCLVPGTYDEAHDKAVQLQKEYDMTFIHPYDDEQVIAGQGTIGLEILDQ
                     LPDVDAVVVPVGGGGLISGIAFAIKTLRPEVKVYGVQAEGAPSMYRSLHEHKYQTLKSA
                     STFADGIQVKTPGELTYQLCEQYVDDIVTVTEDETAAAILSLMENQKLVAEGAGAVPVA
                     AVLFHKLPVEGKKVACVISGGNIDVNILNRVITRGLVMSGRKANLTIALEDKPGQLKKV
                     AEVVSRCGSNVVSVQHDGSDPNMPISSCFLKLTLETRDAAQIEQIRTELTKAGFQLVSE
                     RV"
     CDS             complement(12271..13173)
                     /locus_tag="ctg43_12"
                     /transl_table=11
                     /translation="MKNFAKRISALVLAVVVSAAVLCPAAFAAQLPSLPKDQCVVDGAG
                     VLSSSTVQTITELNAQLESSCSGAQIGVLTVEYTGNDSTEDYATQAFNAWGIGSSSNNN
                     GVLILLVMESAQYADGDYYLTYGDGFRNTTLAKQSSAIAQTMEDQFAAKNYDGAVTTCA
                     RNVANTIADIYGVSLSGGNGSTVQPGYQGGQSSGGSTLTDILTLVVSVVLLIVIIRSMA
                     YVFASPCGWLWCFGGPRPPRGRRRGPHNPPPPPGGFYGGFGGMGGGSFGGGAGRGSFGG
                     GFGGMGGGSSHGGGGGRGR"
     CDS             complement(13170..13928)
                     /locus_tag="ctg43_13"
                     /transl_table=11
                     /translation="MANADFSQNKQTAPGGFDAGSYREKAKPEQVVTLTPRQQKLAALE
                     AKLPAAFSTRAAALALSVVVMLAAFFGFGSAKLRGKYNTARQWFTAGVAADNGYNLSEE
                     LTTRENTAANILTTASNTLGADSAEVLAAQTALNDFSACLQAVQNGGKSQSLTSLPYYQ
                     GSAMHALYQADQALDAAIDQLYAKLQEQAADPMKMGAVQGQYGQFNSAATIIGTLQYNT
                     AVYEYQNEVGGFPASVLGALSGVKEVEPFA"
     CDS             complement(13930..15081)
                     /locus_tag="ctg43_14"
                     /transl_table=11
                     /translation="MADNTLNFDLDAPAVPTLTLDPTPAAVPQEEKPAAAPAPEAQVTL
                     SPEEQAMVDQFAQKIDITNSQQVLQYGSACQKKIGDFSEAALSKVSTKDLGEVGDMITD
                     LIGELKSFDANEEQQKGIMGFFKKKTSQLDALKTKYDKTETNVEKIQSMLEAHQVQLLK
                     DIAMLDKMYELNMAYFKELSMYILAGKKKLADVRANELQQAMDKAKVSGLPEDAQAARD
                     LADQCERFEKKLYDLELTRNISLQMGPQIRLLQNNNTMMAEKIQSTIVNTIPLWKNQMV
                     LALGLAHSQQAMQAERAVTNMTNDLLKKNAEALKLGTIETAKESQRGIVDIETLQQTNK
                     SLIETLDELNKIQSEGRAKRVAAEQELTRIEDELKTKMMEIRS"
     CDS             complement(15125..15754)
                     /locus_tag="ctg43_15"
                     /transl_table=11
                     /translation="MSKIIRTQKPSVLPFYAAALVFVVLCAVLPVYKLWALLVALGGAA
                     VAFGVAQKTCPPRVVEHEVPFHTGVEDVDQMLTDIQQKLDTLHALNEALPDPQLSAAMT
                     RMEKAGRSIVEAVEANPAKAKQVRRFANYYLPDAVNVLQQYAKLAKQGVRGENAAAIRA
                     EVEHNAASIATAFENQLDALYAAESMDLSADLTVLQNMLKGQGLSK"
     CDS             complement(15858..16346)
                     /locus_tag="ctg43_16"
                     /transl_table=11
                     /translation="MSFAPVYDDRSRALILGTWPSPKSREMAFYYGHPQNRFWPLLAAL
                     TGEPLPAREDIAAKKQLLLRHGLALWDTLESCTITGASDASIRDVVPNDIAGLLRKAPI
                     RAVFCNGATAYRIYTKYQQPLTGIPAVRLPSTSPANAACSPARLEEIWGAALADWIVK"
     CDS             complement(16343..17236)
                     /locus_tag="ctg43_17"
                     /transl_table=11
                     /translation="MQYKILASDYDNTLMPFGEAKPRPAVVKAVKKLQAAGGKFVLSTG
                     RSYPGIRDKNQLGGIRYDYAITCNGACVVDRQGNVIAEHPLTSEEMYVLVDFCEDYNYP
                     LQFNFRDAYYAYCEYEYLHTGYQMMNSPGLDCVDGEDQDRHLVDMPHAAFAAMPPQEVE
                     RFHEKYGYLGLHWMQTGAQNADGYCYYDIVRGGMDKGVGLADLCAQMGLTLADAVAVGD
                     SANDVGMLKVAGLSACMANGTPDAKAAADRIIGDVREDGVAALIEELWFDGPRAEPSGK
                     DFGSAWGNIESAGGSL"
     CDS             complement(17375..18262)
                     /locus_tag="ctg43_18"
                     /transl_table=11
                     /translation="MELFLDVLGETLVDTAKMLPFLFLAYLLIEYIEHRHGERIEALLA
                     GGGRWGAVPGAVLGCVPQCGFSAIASNFYASRVITLGTLMAVYLATSDEAIPLLVSMPA
                     YWDKLAVLMVIKVVYAIVVGFVLDFVLRGVLPKGLRGGYTGHADEVDCHEEHSDAEGNE
                     KPIWQAALRHTLEIFVFIFAFSLVFGMIVEGVGEDVFAEMLGGMGFFQPVVAALVGLIP
                     NCAASVLLTQLYVEGALRFSSLVAGLCTGAGVGLAVLWRANPSWKQNLFITGLTWAAGA
                     FVGVAMQVVVAVFA"
     CDS             complement(18563..19333)
                     /locus_tag="ctg43_19"
                     /transl_table=11
                     /translation="MQDQYSRTQLLLGAEAMEKLHHARVAVFGIGGVGGYTVEALARSG
                     VGALDLIDDDKVCLTNLNRQIIATRSTVGQYKVDVAEQRIHDIDPNIKVTTHRCFFGPE
                     TQDDFDFTQYDYVVDAIDTVTGKLALVMKCKEAGTPIICSMGAGNKMDPTRFEVTDIYK
                     TSVCPLAKVMRTECRKRKIKHLKVVYSKEPVMTPIEDDSISCKDHCICPPGTQRKCTAR
                     RTVPGSNAFVPSVAGLIIGGEVIKDLVGFVPLKG"
     CDS             complement(19344..20447)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_synthase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_20"
                     /sec_met_domain="NAD_synthase (E-value: 4.1e-07, bitscore:
                     20.3, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQNPANRPRALIAMSGGVDSSVAACLMQQAGYDCTGITMRLTH
                     NETLGQSGYQTCCSEKDIEDAAEVAFALDMPYQVLDFTADFRAQIIEKFIRVYEAGGTP
                     NPCIDCNKYMKFRHLLDWAEEHGMEYVVTGHYARVEQDAATGRWLLKKGLDEGKDQSYV
                     LYNLTQEQLAHIRLPLGALHKTEVRKIAQEHSFINAQKHDSQDICFVPDGDYARFMEQF
                     TGKHYPAGDFLDQSGKVVGTHSGAVRYTLGQRKGLGLALGAPVYVCGKDMQANTVTVGP
                     ESELFDRIVYAEDVNWIAIPALTGPLRVTARTRYHQAEQQATVYPAENGFRLEFDQPQR
                     APTPGQAAVLYQGDVVLGGGTITRVEK"
     CDS             complement(20516..21964)
                     /locus_tag="ctg43_21"
                     /transl_table=11
                     /translation="MKLTLDPGAAALLDALHAAGYAAYAVGGCVRDSLLGRTAHDWDLC
                     TSALPQQVMELFGTEQCIPTGLQHGTVTIKYGGQLYETTTFRTEGSYTDGRHPDAVQFV
                     PDVREDLARRDFTINAMAYNAAEGLVDPFGGQKDLQNGLLRAVGEPQQRFTEDALRILR
                     LYRFAARFGFTLDAATARAARQLAPHLDCISAERIQEELAKLLVAPQPGAYLEPAVLAV
                     VLPELTPAALEAAKPVVDACPAGEENLPVRWAALLGTLGEADTRRVLKRLRCSNACIEE
                     TAVLVRETAGEGVCGSFLLGHEFELRHPADASCLEQHSHPAGRCPNSNSLFPPQAAVVA
                     VAGHSIARPTACGSRVPPQRTVLGETPAHAPERASDTHLRRLLGRYGLCTVERLCALCA
                     ALHPQDAQNCALAAQRARQLEADGVCCRVSQLAVNGRDLMAAGIPAGPALRRVLETLLD
                     GVIRAEYPNEKPVLLAAAQKIIAS"
ORIGIN
        1 tgcccgtaaa aagtgcattt ttccacggaa gaagttcgta caacctgtac ggtctgtact
       61 tgtacgcacc cgtacggcga atcgaagcaa attaaaacgt ggtatcgttt atatttcgga
      121 tttccgtacg tcgtacgaac cgtacaggtt atttgaagtc cgtacgcatt tttttcgccg
      181 catacggaac tgacaccgtt cccacggtag gaacggtgtc gtaactctcc cgcaggagac
      241 gttccccctc ggagagccca ctacactttg cagcccatag ggatgaaagt gttatagtgg
      301 gttattacac ttccgtggaa gtgcatctcc gtcccccgtc accttcctct gaaccttgaa
      361 aggagggatg ccctttggca agaaacgatg gcatcgaccg caccagtgtc cgaaatctcg
      421 ccgtttcgga caaggctgtt agcaataccc agcagcacaa cgaacgcgaa aaagacagct
      481 atcgaaaccc cgacattatc ccccagcgcg ttgcatggaa cgtccatttc aaaaagccaa
      541 ccgccagcta caccgaccta ttcgcccaac tggaagccgc cggaaccatc tccacgcgcg
      601 gcttgaagcc ggatgccacc cactactgcg aacttgtctt tgatgtcaac tcagcctact
      661 ttgacaacca cggcggctac gagttcgcca agcagttcta tgcggatgcc tacaaagctg
      721 ctgtgcaaat cgtaggcggt gaacagtata tcctcttggc tgtcatgcat gccgatgaaa
      781 tcaaccgtgc catgacagaa gcattaggcc gggaggtcta ccactaccac ctccatgtgg
      841 tctatgtacc tgtggtggaa aagcagatcc tgtggtcgaa acgctgcaag gacaaggcac
      901 tggtcggcac agtcaaggag accgtcatgc aggtcagccg gagcaagaag tgggcatcca
      961 aacctctgct ggacgatgcc ggaaagcctg tcctgcaaaa gaacggcaag ccagtcctga
     1021 agaagtcgta cagcgtcctg caagacgatt tcttcaacta tatgcgtact gccgggtaca
     1081 ccgatataga gcgcggcgaa cgtggcagca ccgaagaaca cctaaccgtc acccagttca
     1141 aagtccaacg ggagcaggaa cggctggaca ccctgaccac ccaagccgac cagcaggcac
     1201 aatcgcttgc taaaaccagt cagactctct ccaaaaaaga gaaggagctt gccgctgtgc
     1261 agaaaaagac cactctcacg aaagaagccc tcattcatgc gcgtgatctg gattatctcg
     1321 gcaagcgcac cttcctcggc aactactcgc tgaccgaaga agaattttcc aagctgaaaa
     1381 agcaagccga ccacggctat atgatggacg tggagaaccg ccgcctgaaa gaagaacttt
     1441 ccgctgccaa gaaagaaact gcccgttgga gcagcaagta ccacgacctt tggtatgatg
     1501 tgaagcctta tctggatgct ctccaccgtg cgcccgaact ggtgcgcggc tttctggaaa
     1561 agattcttgc ccccaagcag gagcgcacca taaatgtgcc gcagaaaaac cgcaagcgcg
     1621 ggcaggatat ggaactttga gtttcggagg ataccacttg aacaaaaaga agaagtcgaa
     1681 caaatccggc tacccggatg aagcaatcaa gaccctagca cgttgtttct atccctccat
     1741 ggttgatttt ttcaacagcg aggaaggcca gcgtgaatat gagaagtggc tgaaagagca
     1801 ggaggctctg aacgctgcac ccatcgcagc ctaaaaacag caggacgctc ccggaaaggg
     1861 gaacgccctg cattacataa atgtttctca ccgaggtgtg tccgcttggg cacacctttt
     1921 atttttttgt ccttaatctt ctagcccatg gctcccggtt gtattcttca aatattcctc
     1981 tgggtcgccg ttcaggatca aatcggcata gcccagcggg tcattataga taaggtagtc
     2041 caattcggtc tgctgtgcca tggtcacatc caacgcatcc tcgaccccgg tgcagtcaat
     2101 ggagattttt ctcccatccc ggagccgcag ctccacacat ccagtgtcca tgttgaaatg
     2161 gcaggctctt gcatcgtact tcataatcgc atcctccaaa tcttgttatt ggcttacggt
     2221 ctatgacaag gtatcggagt tttacgccgt ccacgggagc cttcattctc aaacccgaag
     2281 aaaacgaaaa acccgaaccc ttctccaatc ggaaataggt tcggattttt cttgtttggt
     2341 gggcgcgggt ggattcgaac caccgaagct gaaagcagca gatttacagt ctgtccccat
     2401 tggccactcg ggaacacgcc catattcagt tgttgtgcat ccgtgcgccg gacgacttgt
     2461 ttattttagc atgagaaaag ggttttgtca accacctttt ttcacttttt ttcagcaggc
     2521 ttactgtccc ccgcccgccg cgcttcatcc ggttgaattg cgtcctgttt tatgttaaaa
     2581 taatgtaaag attctacaca ttttacaggc aggagtgggt cattgcatgg agtcaacaat
     2641 cagcgccgcc ccgcaaattt ctatcgaccg ggaaaagacg ctgcgcaacc accggcgtta
     2701 ctgggtgctg cggcgtgcac aggacatcgt attctccctg ctggcgctga tcctgcttgc
     2761 gccgctggca ctgctgatca gccttgccat cgtgctggac agccccggag acggagctat
     2821 tttccggcag cggcgggtag gacgggacgg caagctgttc tggctgtata agtttcgtac
     2881 catgtgcccg gacgccgagg agcagctgaa tgagctgctg agccagaacc agatggacgg
     2941 cccggtgttc aagatcaagg gcgacccccg cattacccgg gtgggacgtt ttctgcgcaa
     3001 gaccagtctg gacgagctgc cacagctgct caacgtgctg cagggcgata tgagcatcgt
     3061 ggggccgcgc cccgcactgc cccgggaggt agagctgtac agcgactacc agcgccagcg
     3121 gctgtacgtc acccccggac tgagctgcta ctggcaaatc gcaccccacc gtaacgagat
     3181 gagctttgac gagtgggtgg cgctggatat gaaatacatc caggagcgca gcttctgggt
     3241 ggactggaag atcatcttcc tcaccgtccg cgccatgctc atgaaatacg gagagtgaca
     3301 aaagcgcctg ttgtgcatcc gcacaacagg cgctttcgtt acgtttattt cagcactgca
     3361 cccagatttg cactggtgac catgcgggcg taacggctca gccagccggt cttgatgttg
     3421 ggctcgggcg caacgtactt tgccttgcgc tcggccagca ctgcatcgct gacctccagc
     3481 gtgatggagg cgttggggat atcaatggaa atggtatccc cttcctcgat caggccgata
     3541 gggccgccgg aagctgcttc cgggctgacg tggccaatgg cagcgccgcg ggatgcaccg
     3601 gagaagcggc catccgtgat aagagcaacc gtcttatcca gcttcatgcc tgccagcgca
     3661 gaggtggggt tgagcatctc ccgcataccc gggccgccct tggggccttc gtagcggatg
     3721 accaccacat cgcccgggac gatcttgccc gcgtagatag cggcaatggc ttcctcttcg
     3781 ctgttgaaca cccgcgccgg gccggaatgc tgctgcatct ccggggcgac ggcgctgcgc
     3841 ttgacaacgc acccgtccgg ggcaatgttg ccccacagga tctgcagacc gccggtctgg
     3901 gagtaggggt tctcgatggg acggatggcc ttttcgttca ggatatgggc acccttgatg
     3961 ttctcgccaa gggtcttgcc ggtgacggtg ggcacatcca gatccagcaa gcccttcttt
     4021 gccagctctg cctgcaccgc cgggatgccg cccgctgcgt acagatccgg catatgggtg
     4081 gggcctgccg gtgccaaatg gcaaaggttg ggggtcttgg cgctgatctc gttgaacagc
     4141 ttcaggtcga tgggcacacc ggcctcgtag gcgatagcca gcaggtgcag caccgtgttg
     4201 gtggagcagc ccagcgccat atcacaggtc agcgcgttgc ggatggagcg ctcgttgatg
     4261 atctggcgtg cggtgatgcc cttgcgcacc atctccatca cagccatacc ggcgtgcttt
     4321 gccagctgca ggcgcttgga gtacacagcc gggatggtgc cgttgccggg cagggcgatg
     4381 ccgatggctt cgcacaggca gttcatgctg ttggcagtgt acataccgga gcagctgccg
     4441 cagctggggc agcagttgca ggtgcagtcc tccagctgct cgtcggtgat cataccggcc
     4501 ttataagcac ccacggcctc gaacattttg gaaaggctca cttcctcgcc gccgtaagta
     4561 ccggccagca tagggccgcc ggagcagacc acagcgggca catccatgcg caccgctgcc
     4621 attaccatgc cgggcacgat cttatcgcag ttgggcacca gcacaaggcc gtccagctgg
     4681 tgtgccatca gcatggtttc cacgctgtcg cagatcagct cgcgggaggc cagagagtac
     4741 ttcatgccca catgacccat ggcgatgccg tcgcatacgc cgatggcggg gatcaggatg
     4801 ggcgtgccgc ctgccatctg cacaccggcc ttgacggcat cggcgatctt gtccagattc
     4861 atgtgcccgg gcacgatctc gctgtgggcg ctcactacgc cgatgagcgg gcgctccagc
     4921 tcctccgggg tatagcccag cgcataaaac aggctgcggt tgggcgcgcg ctccgagcct
     4981 ttggtcacgt tgtcacttct cattgcaaat cctcttttct gataaaaccc tctccgtcac
     5041 ggctgcgccg tgccacctct cccgaggggg agaggttttc gcggagaagc tataaggctc
     5101 ccttttcaac aaaagctccc cctttcgggg gagctgccgc cgaaaggcgg cctgagaggg
     5161 ttctcctctt acttcttcag ccagctcatc atgctgcgca gctcagcacc caccttctcg
     5221 atgggcagct cagcctccat acggcgcttg gcaaggaagt gcaccttgcg gccgcccttg
     5281 gggctcatct cggtcaggaa ctcagaagca aaggtgccgt cctggatctc ggtcagaacc
     5341 ttcttcatct ccttgcgggt ctcctcggta atcaggcgct tgccggtgcg gtagtcgccg
     5401 tactcggcag tgttggagat ggagtagcgc atcttggaga agccgccctc gttgatcagg
     5461 tcaacgatca gcttcatctc gtggcaggtc tcaaagtagg ccatctcggg ctcgtagccg
     5521 gcctccacca gcgtatcgaa gccggcgtgg atcagctcgg aaacaccgcc gcacagcacg
     5581 gcctgctcgc cgaacagatc ggtctcggtc tcctccttga aggtggtctg cagaatgcct
     5641 gcacggcctg cgccgatgcc ggaagcataa gccagtgcga tatccttggc cttaccggtg
     5701 tagtcctgct ccacgcagat cagagagggg cagccctcgc cctcggtgta caggcggcgc
     5761 acgatgtggc cggggccctt gggagcgatc atgatgacgt ccacgttctt gggcgcggtg
     5821 atggtcttga agtggatgtt gaagccgtgt gcaaaggcca gtgccttgcc ctcggtcatg
     5881 tagggagcaa cctgggtgtt gtagatatcg gcgcacagct catcgggcac cagcatcatg
     5941 acaacatcgc cggccttggc agcctcttcc acctccatga ccttgaagtt gtcatgggtg
     6001 gcagcgaact cagaagcctt tgcccagtga gcagaaccct tgcgcaggcc gaccacaacg
     6061 ttgacgccgc tctcagccag attctcagag tgtgcatgac cctggctgcc gaagccgatg
     6121 acagcgacgg tcttgccgtc cagcacgccg aggttgcagt cggaatcgta gtatttcttg
     6181 atagccataa tcgttagtct ccttttacat taactggttg gtttatcttc cggtcttgta
     6241 tgctctgttc tatctttcgc tcaccctgag cggaaaagca atgtaattat gcccgtcttg
     6301 cgcccggcgg gggcagctgg acggagcgca cctcctgcgg cggcttctgg atatgctggt
     6361 gcatcccgcc gcgctccagt gcagtaacgc cggtgcggca ctgctcaagg atgttgtagc
     6421 cctcgaacat tttcaaaaat gcgtccagct tgtccggccg gccgatcaac tcaaacacca
     6481 tgctgtccgg ggaaagatcg atgatctttg ccttgtagat gcaggcgatc tcccgcagct
     6541 ctgtgcggtt gtgcacgtcc gattccacct tgagcagcag cagctcccgc tccagcgctt
     6601 tttcgctgtc cagcacgaac acctgccggg tgacttccag ccgctcggtc tgcaatacca
     6661 gctgctgcaa ggccttttca tcgctggtaa tggtcactgt gatgcggctg actgccgggt
     6721 cgttggtggc ggacaccgta aggctgtcga tattgaagcc gcggcggcag aacaggctgg
     6781 acacccgggc cagaacgccg ctctggttgt ccaccagcag gctgatgacc ctgcgctgat
     6841 cagatttcat gatgctgtgt cctccttatt ccatgatgat gtcgttgata tcgccgccgc
     6901 cggggatcat gggcagcacc ttttcgtcct tgtcaatgat gcactcgatc caagtggggc
     6961 ctttctgctg caaggcatct gcaaaggctt cctgaaactc cggcagattg gtgcagcggt
     7021 agcccttcag gccaaagccg tctgccagct tgacaaaatc ggtcttgcgg tgggggtcgg
     7081 tctggctgta acgcttgccg taaaagctgg tctgccactg gcgcaccatg cccagcaccg
     7141 agttattgaa gatgaccgtg atgatgggca gctcgtagct gacagcggtg caggcttcgt
     7201 tcaggttcat gtggaaggag gcgtcaccag taaacatcac cacacgctgc tggcgtccca
     7261 gtgccatctg ggcaccaatg gcagcgccgt agccaaagcc catggtgcca aggccgccgc
     7321 tggtgataaa gccacggctc ttggtgtggc gcaggtactg cgccgcccac atctggtgct
     7381 gacccacgtc ggtaacatac acggcgtcgg ggccgcactg gttgcacacc tcgccgatga
     7441 cctgatgggg catcagccgg gtggggtcag acacggggtg gtaatcctgt gcctgccagc
     7501 tctggatcat cttcatccat tccgggtgct tggcgggctt gatctggggc agcatggcgt
     7561 tcagtacata ggctgcatcg cccacgatgg aaagatccac atccacgttc ttgcccagct
     7621 cgctggcgtc aatatcgatc tggatgatgg tggcgttttt ggcaaaggtc ttggggttca
     7681 gcgccacgcg gtcggaaaag cgggtaccca ccgcgatgag cacatcgcac tctgccaccg
     7741 cccggttgga ggtgtagcag ccgtgcatcc ccagcatccc cagattcatc gggtcgccgt
     7801 agggcacaac gcctgcggcc atcagggtgt aggttgcggg aatctccgcc ttgtgcagca
     7861 gatcccgcaa cggctggcag ctggctgcgc tgcgcacgcc gccgccaaag tacaccagcg
     7921 gacgctgtgc ggcgttgatg aggtctgccg cccagtgcac ctgctcctca ttataggtag
     7981 tcacggtgcg gataggctcc ggctgcttgg gggtgaactc gcacactgct gcagtcacgt
     8041 ccttggggat atccaccagc accgggccct tgcggccgct ctgcgcaatg cggaaggctg
     8101 cccgcatggt gtcagccaag tcctctaccc ggcgcaccgt gaagttatgc tttgtgatgg
     8161 gcaccgtaat gccctcgatg taagcttcct gaaagccgtc cttgccgatg ctgctggtgg
     8221 gcacgttgcc ggtaaaggcc accatgggca ccgagtccat ataggcggtg gcaatgccgg
     8281 tgaccagatt ggtggcaccc gggccgctgg tagccagcac cacgccggtg cggccggtgg
     8341 cgcgggcgta gccgtccgca gcatgggctg cgccctgctc gtgggcggta agcacatggg
     8401 tgatgcggtc ggcattctta tacagctcgt cgtaaaggtt cagcacagcg ccgccggggt
     8461 agccaaaaag agtgtccact ccctgctcgc acaggacctc tacaaagatc tgagaaccat
     8521 tcaactgcat ggtgttgctc ctattcctgt tccacttctt atccattccc ccggggagag
     8581 cttttgaaaa agaaaaagcc cttgtcccct gctttcttca agagacaaag accttgtaac
     8641 atcaagctct ctgcggtacc actctcgttg gcgtgctgtg cacaccctct cacgggcttc
     8701 caacaaagcc ctgcacggta acggctgcaa ccggcgctgc ttacaggggt ttgcacccgt
     8761 tgggcaggct gctccgggat gattttccgc acgaaacgct gactgccttg caccagacgg
     8821 cagctctctg aacagtgggg atcgtgtggt actttttccc atctgcgcat ttgttgatgt
     8881 aaattatact ataaaccggg cttttgtcaa tcgacaattt gtaacctgaa tcaccccaaa
     8941 gatgaagcat ttttaacacc ccttgcatcc ccgcccgaac cgctgtatac ttttgatatc
     9001 cgcgtacctg cgttttgtag ggtatgtgcc aatggagagg aaaagggatc gacctatgaa
     9061 actgagagaa tggaatgccc atctgcatgg gcttgttgtg ttccgcgccc tgctgaacga
     9121 ccctgttgtg gcaaagcttt tagacctgac cgaccgcatg gaagccggca gcacctccta
     9181 cggcccggtg tgcgatgccg tagccgcctt tgaggccgct ttgttcgagt acaccaccaa
     9241 ctggggcagc tacctgagca atgctgtgct ggaggccgag accatctgcg tgcggcaggc
     9301 cgccgccggg cagctggacg cgctgctgca aagcgccttg gacagcgagc tgcagttttt
     9361 gcagcagctg tgcgggctga cgctggacga gctgtttcag accgcctact cggagcaggc
     9421 gcagcggccg gagttggcgt tcctgccccg gtggcagacc tgtgagcttg accttgccgc
     9481 cgcctacgcc cagcgcatga gcgaggtggg caaaaagggc tacggtatgt ttgcaaagca
     9541 ccatgtattc acggtggaga acggccagct tgtgccggta aaataccccg acccgcagcg
     9601 cctttccgag ctgccaggct acgagaagga gcgggaaaag gtgatcgcca acacaaaggc
     9661 actgctagcc gggatgcccg ccaacaatgt gctgctgtac ggtgacgccg gtaccggcaa
     9721 atccagcgcg gtaaaggcca ttgccaacga gtttgcgccc gagggactgc ggctggtaga
     9781 ggtaaaaaag aaccagctgt accagatccc cgacctgatg gataagctgg cggcaaaccc
     9841 gctcaagttc attttgttca tcgacgacct gagctttacc gccaacgacg acaactttgc
     9901 cgccctgaag gccattttgg agggcagcgt aggcggccgt gcccagaaca ttgcggtgta
     9961 cgccacctcc aaccgccgcc acctcatcaa ggagactctc tcagaccgca ccggcgacga
    10021 catccacgaa gccgacaccc ggcaggagct gatgagcctt tccgcccggt tcggcctgac
    10081 ggtcaccttc cagcggccgg aaaaggcacg gttcgagacc attctggagg agctggcaaa
    10141 gcagcacaac atccagatgc ccaccgagca gctgctgctc aaggccgagg cctttgccct
    10201 gcgtgccggc ggccgcagcc cccgggtggc caagcagttc atcgagcaat gcgaggccgg
    10261 ggtgcagaag taaatgcacc agttttaagc gttatcaaaa aacgggacac caaagcatcc
    10321 gcagatgctt cggcgtcccg tttttcctat ctttattcgc tcagtcccgc acggcgatgc
    10381 actcaatctc cagctttgcg cccttgggga tggctgccac ctgcacgcag ctgcgggcgg
    10441 ggaacggctc ggcaaaggcc ttggcgtact ctgcgttcac tgcggcaaaa tcgttgatgt
    10501 cggccagaaa gatcaccgtc ttgaccacgt tgttcatgga aagccccgcc tcggccagaa
    10561 tcgctttcag gttggcaagg ctctgtgcgg cctgctgctc cacggtatcg gccatggtgc
    10621 cggtggcggg gtctaccggg agctgcccgg aaacaaacac catattgccc agatccagtg
    10681 cctgactgta agggccgatg gcggcaggtg cgttggcggt agatacgact ttcatggtat
    10741 attttctcct ttatattaca tcaggtttag aacaaattcg cttttttctt cggatagagc
    10801 cagatgaggg ggtaatttcc cgtaagccgc tgcttgcctg tgccctcatc cgtctgctca
    10861 ctccgttcgc atccaccttc ccccgtccgg gggaaggttt tcactcttgc aaacgatgaa
    10921 gtttacaccc gctcgctgac cagctggaaa ccggccttcg tcagctctgt gcggatctgc
    10981 tcgatctggg cggcatcgcg ggtctccagc gtcagcttga ggaagcagct ggaaatgggc
    11041 atattggggt cggagccatc gtgctgcacc gacaccacgt tgctgccgca gcgggacacc
    11101 acctcggcca cctttttcag ctggccgggt ttgtcctcca gtgcgatggt cagatttgcc
    11161 ttgcggccgc tcatcacaag gccgcgggtg ataacgcggt tcaggatatt cacatcaatg
    11221 ttgccgccgg agatgacgca ggccaccttt ttgccctcta ccggcagctt gtggaacagc
    11281 accgccgcca ccggcacagc gcctgcaccc tcggccacca gcttctggtt ctccatcagg
    11341 gagaggatgg ccgccgccgt ctcgtcctcg gtcacggtga cgatatcgtc cacatactgc
    11401 tcgcacagct ggtaggtcag ctcgcccggg gtcttgacct gaatgccgtc cgcaaaggtg
    11461 gaagcagatt tcagggtctg gtacttgtgc tcgtgcaggc tgcggtacat actgggggca
    11521 ccctcggcct gtacgccgta caccttgacc tccgggcgca gggtcttgat ggcaaaggca
    11581 atgccggaga tcagtccgcc gccgcccacc ggcaccacca cagcgtccac atccggcagc
    11641 tggtcaagga tctccaagcc gatggtaccc tgcccggcga tgacctgctc gtcatcgtag
    11701 gggtggataa aggtcatgtc gtactccttt tgcagctgca cggccttgtc gtgggcttcg
    11761 tcgtaggtgc cgggcacaag gcagacctcc gcgcccagat ttttggtgtt ttccaccttc
    11821 atcaggggtg cgccgtccgg catacagacg atgctgcgga tgccgcgccg ggtagccgcc
    11881 agcgccacac cctgcgcatg gttgcccgca gagcaggcaa tgacgccctt ggcgctctcc
    11941 tcctcggaaa gctggctgat tttatagtaa gcgccccgca ccttaaagct gccggtggcc
    12001 tgcaggttct cggtcttaag gtacagctgg cagtccttgg acagcttggg ggcttcgatg
    12061 aggtcggtct tgcgcgctac gtccttcagc acaaaggcgg cgtggtagat cttatccaga
    12121 gtcagcatga cagatacttc ctttattttt cgtgatgtca tccagtataa gttacaaaaa
    12181 ttgttttgtc aaatgaattc cattcacgat aaaaggcgta aaaaagagaa aggcagtggt
    12241 aaagccaccg cctttctctt tttattctca ttaccgccca cggccaccgc cgccgccatg
    12301 gctggaacca ccgcccatgc caccgaagcc gccgccaaag ctgccgcgcc cggcacctcc
    12361 cccgaaggag ccgccgccca tgccgccaaa gccgccgtag aagccgcccg gcgggggcgg
    12421 cgggttatgc gggccgcgcc gccgtccacg gggaggccgc ggcccaccga agcaccacag
    12481 ccagccgcag gggctggcaa aaacataggc catcgaccgg ataatgacga tgagcagcac
    12541 aacgctgacc acaagggtca ggatgtcggt cagggtgctg ccgccgctgc tctgcccgcc
    12601 ctgatagccg ggctgcacgg tgctgccgtt gccgccggaa aggctgactc cgtaaatatc
    12661 cgcgatggtg tttgccacgt tgcgggcaca ggtggtcacc gcgccgtcat aattctttgc
    12721 ggcgaactgg tcttccatgg tctgggcgat ggcgctggac tgctttgcca gcgtggtgtt
    12781 gcggaagccg tcgccatagg tcaggtagta gtcgccgtcc gcatactgtg ccgactccat
    12841 cacaagcagg atcagaacac cgttattgtt ggaggacgaa ccgatacccc aggcgttgaa
    12901 agcctgtgtg gcgtaatcct ctgtggaatc attgcctgtg tattctactg tcagtacacc
    12961 gatttgcgcg ccgctgcagc tggattccaa ctgggcgttc agttcggtga tggtctgcac
    13021 ggtgctgctg ctcagcacac cagcaccatc caccacgcac tgatctttgg gcaggctggg
    13081 cagctgggcg gcaaaggccg ccgggcacag cactgccgca ctgaccacca cggccagcac
    13141 cagtgcgctg atgcgttttg caaagttttt catgcgaagg gctcaacctc cttcacgccg
    13201 gacaaagcgc ccagcacact ggccgggaag ccgccgactt cattctgata ttcatacacc
    13261 gccgtattgt actgcaaagt accaatgatg gtggctgcgc tgttgaactg gccgtactgt
    13321 ccctgcaccg cacccatctt catggggtct gcggcctgct cctgcaattt tgcatacagc
    13381 tggtcgatgg cggcgtccag tgcctggtcg gcctgataca gcgcgtgcat cgcgctgccc
    13441 tgataatagg gcagcgaggt cagcgactgg cttttgccgc cgttctgcac cgcctgcaga
    13501 caagcggaga aatcgttcag cgccgtctgt gcagccagca cctcggcgct gtctgcacca
    13561 agagtattgg aggcggtggt caggatgttc gccgccgtat tctcccgggt ggtcagctcc
    13621 tcgctcaggt tataaccgtt gtcggcggcg acccctgcgg tgaaccactg acgggcagtg
    13681 ttgtacttgc cgcgcagctt ggcgctgcca aagccgaaaa aagcggccag catcaccacc
    13741 acgctcaagg ccagcgccgc cgcccgggtg gaaaacgctg cgggcagctt tgcttccagt
    13801 gcggccagct tctgctggcg gggcgtcagc gttacgacct gctccggctt tgctttttcg
    13861 cggtagctgc ccgcgtcaaa gccgccggga gcggtttgtt tgttctgaga aaaatcagcg
    13921 tttgccattt cagctccgga tctccatcat tttggttttc agctcgtcct cgatgcgggt
    13981 cagctcctgc tcggcggcaa cgcgctttgc acgaccctcg ctctggatct tgttcagttc
    14041 gtccagcgtc tcgatcaggc tcttgttggt ctgctgcagc gtctcgatat ccacgatgcc
    14101 gcgctggctc tccttggcgg tctcgatggt gcccagcttc agtgcctcgg cgttcttctt
    14161 cagcaggtcg ttggtcatgt tggtcacggc gcgctcggcc tgcatggcct gctggctgtg
    14221 tgccagaccc agtgccagca ccatctggtt cttccacagc gggatggtat tcacgatggt
    14281 ggactggatc ttttccgcca tcatggtgtt gttgttctgc agcagacgga tctgggggcc
    14341 catctgcaaa ctgatgttgc gggtcagttc cagatcgtac agctttttct caaagcgctc
    14401 gcactggtcg gcaaggtcgc gggcggcctg tgcgtcctcc ggcagaccgg agaccttggc
    14461 cttatccatg gcctgctgca attcgttggc acgcacatcg gccagctttt tcttgccggc
    14521 aaggatatac atactcagtt ccttgaagta agccatgttc agctcgtaca tcttgtccag
    14581 catggcgatg tccttgagca gctgcacctg atgggcttcc agcatggact ggattttttc
    14641 cacattggtc tcggtcttgt cgtacttggt cttgagggca tccagctggc tggtcttttt
    14701 cttgaaaaag cccataatgc ccttctgctg ctcctcgttg gcatcaaaac tcttcagctc
    14761 gccaatgagg tcggtgatca tatcgcccac ctcgcccaga tccttggtgg acaccttgga
    14821 gagggctgct tcggagaaat cgccgatctt cttctggcag gcagagccgt actgcagcac
    14881 ctgctggctg ttggtgatat cgatcttctg ggcaaactga tccaccatgg cctgctcctc
    14941 ggggctcagg gtcacctgtg cctccggggc gggagcggcg gcgggctttt cctcctgcgg
    15001 cacagcagcg ggggtggggt ccagcgtcag ggtgggcact gcgggggcat ccaggtcaaa
    15061 gttcagagta ttgtcagcca taagtgattc cttcctttca aaatcccgag gggatattct
    15121 ggttttactt gctcagaccc tgccctttca gcatattctg caaaacggtc aggtctgcgg
    15181 acaggtccat gctctctgcc gcgtacaggg catccagctg gttttcaaaa gccgtggcaa
    15241 tggaggcagc gttgtgctcc acctcggcgc ggatggcggc ggcgttctcg ccccgcacac
    15301 cctgctttgc aagctttgcg tactgctgca aaacgtttac ggcgtccggc agatagtagt
    15361 tggcaaaccg gcgcacctgc tttgccttgg cggggtttgc ttccacggct tccacgatgg
    15421 agcgtcccgc cttttccatg cgggtcatgg cggcagacag ctgcgggtcg ggcaaagcct
    15481 cgttcagtgc gtgcagggtg tccagcttct gctggatatc ggtcagcatc tggtccacat
    15541 cctccacacc ggtgtggaag ggtacctcgt gctccaccac ccggggcggg caggtttttt
    15601 gtgccacgcc aaaggccacg gcggcaccgc ccagcgccac cagcagtgcc cataatttgt
    15661 ataccggcag caccgcgcac agtaccacga acaccagcgc cgccgcataa aagggcagca
    15721 cgctgggctt ttgggtgcgg atgatcttgc tcatggtcat ttctccttgt ccggggcagt
    15781 gcgcccctta tgatatccat aatacaacgt ccgcaaaaaa acgcaagtat cccgcaaaag
    15841 aatttacagc cttgtcatca ttttacgatc cagtccgcca gcgcagcgcc ccaaatctcc
    15901 tccagccggg cggggctgca ggcggcgttg gcggggcttg tactgggcag acggacagcc
    15961 gggatgccgg taagcggctg ctgatatttt gtgtagatac ggtacgctgt ggcaccgttg
    16021 cagaacaccg cccggatggg tgctttgcgc agcagcccgg cgatatcgtt gggcaccaca
    16081 tcccggatgg aggcatccga tgcgccggtg atggtgcagc tttccagcgt atcccacagc
    16141 gccagcccgt ggcgcaaaag cagctgcttt ttggcggcga tatcctcccg cgcaggcagc
    16201 ggctctccgg tcagcgccgc cagcagcggc cagaaccggt tttgcgggtg gccgtaataa
    16261 aaggccatct cccggctttt ggggctgggc catgtgccca agatcagcgc ccggctgcgg
    16321 tcatcgtaca ccggtgcaaa gctcataagc tgccgcctgc gctttcaata ttgccccatg
    16381 cggagccaaa atctttgccg gagggctccg cgcgggggcc gtcgaaccac agttcctcga
    16441 tcagcgccgc cacgccatcc tcccgcacgt ccccgatgat ccggtcagca gcggccttgg
    16501 cgtccggggt gccgtttgcc atgcaggcac tcaggcccgc gactttcagc atccccacat
    16561 cgttggcaga atcgcccaca gccacggcat ccgccagcgt aagccccatc tgtgcacaca
    16621 ggtcggcaag ccctacgccc ttatccatgc cgccgcgcac gatatcgtag tagcagtagc
    16681 catccgcgtt ctgcgcgccc gtctgcatcc agtgcaggcc aaggtagccg tatttttcgt
    16741 ggaagcgctc cacttcctgc ggcggcatgg cggcaaaggc ggcgtggggc atatccacca
    16801 gatgcctgtc ctgatcttct ccgtccacgc agtccagccc ggggctgttc atcatctgat
    16861 agccggtgtg cagatactcg tactcgcagt aggcgtaata ggcatcccgg aagttgaatt
    16921 gcagcgggta gttataatcc tcgcagaaat ccaccagcac atacatctcc tcgctggtaa
    16981 gcggatgctc ggctattaca ttgccctgcc tgtccaccac gcaggcaccg ttgcaggtaa
    17041 tggcgtagtc gtaccggatg ccgcccaact ggtttttatc ccggataccc gggtaggagc
    17101 ggccggtgct gagcacgaac ttgcccccgg cggcctgcag cttttttacc gcctttacca
    17161 ccgccgggcg gggctttgcc tcgccaaagg gcatcagcgt gttgtcgtaa tcgcttgcca
    17221 gaatcttata ttgcatggtc atctctcctg tgtgcatcgt tttctcccag tataacacat
    17281 ttcaaagtcc agcgggagag ggggaaaaga aaaatgggac agcagaatac ccgcaggcat
    17341 cccactgtcc cgaaattcaa aatatctttc cttatcaggc aaacaccgcc acgaccacct
    17401 gcatggccac gcccacaaag gcaccggcgg cccatgtcag gccggtgatg aagaggttct
    17461 gcttccacga ggggttggcg cgccacagca cagccaagcc cacacccgca ccggtgcaca
    17521 gccccgccac aaggctggaa aagcgcagcg cgccctccac atacagctgg gtcagcagca
    17581 cgctggcggc gcagttgggg atcagcccca ccagggccgc caccaccggc tggaagaagc
    17641 ccatgccgcc cagcatttcg gcgaatacgt cctcgcccac gccctccacg atcatgccga
    17701 acaccagact gaaggcgaag atgaacacaa agatctccag cgtatggcgc agcgccgcct
    17761 gccagatggg cttttcgttg ccctcggcat cgctgtgctc ctcgtggcag tccacctcgt
    17821 ctgcatggcc ggtgtagccg ccccgcagac ctttgggcag cacgccccgc agcacaaaat
    17881 ccagcacaaa gcccaccacg atggcgtaca ccaccttgat gaccatcagg acggccagct
    17941 tatcccagta ggcgggcatg gagaccagca gcgggatagc ctcatcgctg gtggcaaggt
    18001 acaccgccat cagcgtgccc agcgtgatga cccgggaggc gtagaagttg gacgcaatgg
    18061 cggagaagcc gcactgcggc acacagccca gtaccgcacc cggcacagca ccccagcgcc
    18121 cgccgcccgc cagcagcgcc tcgatgcgct cgccgtggcg gtgctcgata tactcgatca
    18181 gcaggtaggc cagaaacaga aagggcagca tcttggcggt atccaccaag gtttcgccca
    18241 aaacatccag aaacagttcc ataaataatc gctccaaaga cccgcatggg gtcgtctctt
    18301 aacaatttgc aatcagtttg cattttcgtg cagggaagat tatacacgat atccttccca
    18361 attgcaatac caaattgcaa attggttgca attttatgtt atggaacgtt gcagcgcgta
    18421 aaaagcgtga aaaagaggtt ctgaaaagcc cgcgggcttt tcagaacctc aaaatttcaa
    18481 atcattcttc cgctgatgat gcgcagagca acacggagcg cattctaaat cgtcccacgc
    18541 agcaaggaag ctgtggcctg ttttacccct tcagcggtac aaagcccaca aggtccttga
    18601 tgacctcacc gccgatgatc agaccggcca ccgagggtac aaaggcgttg gagcccggca
    18661 cggtgcgccg tgcggtgcac ttgcgctggg tgcccggggg acagatgcag tggtccttgc
    18721 agctgatgga gtcatcctcg atgggagtca tgacaggctc cttggagtag accaccttca
    18781 ggtgcttgat cttgcgcttg cggcactcgg tacgcatcac cttggccagc gggcagaccg
    18841 aggtcttgta gatatcggtc acctcaaagc gggtgggatc catcttgttg cctgcgccca
    18901 tggagcagat gatgggggtg cccgcctcct tgcatttcat caccagcgcc agcttgccgg
    18961 taacggtgtc gatggcgtcc accacatagt cgtactgggt aaaatcgaaa tcgtcctgcg
    19021 tctccgggcc aaagaagcac cggtgggtag tcaccttgat gttggggtcg atatcgtgga
    19081 tgcgctgttc tgccacatcc accttatact gccctaccgt gctgcgggtg gcgatgatct
    19141 gacggttgag attggtcagg cagaccttat cgtcatcgat cagatccagt gcgcccacgc
    19201 cgctgcgtgc cagtgcctcc accgtgtagc cgcccacgcc gccgatgcca aacactgcca
    19261 cccgggcgtg gtgcagcttt tccatagcct ctgcacccag cagcagctgg gtgcgggaat
    19321 attgatcctg cattttgttc tccttacttt tctacgcggg tgatggtgcc gccacccagc
    19381 accacatcgc cctgatacag cacggcagcc tgtcccgggg tgggggcacg ctgaggctgg
    19441 tcgaattcca gccggaagcc gttttctgcg gggtagacgg tggcctgctg ctcggcctga
    19501 tgataccggg tgcgggcagt gacccgcagc ggcccggtca gcgccggaat ggcgatccag
    19561 ttcacatcct ctgcgtaaac gatgcggtca aacagttcgc tttccggccc gacggtgacg
    19621 gtattggcct gcatatcctt gccgcagacg tacaccggcg cgcccagcgc aaggccaagc
    19681 cccttgcgct gccccagcgt gtagcgcact gcgccgctgt gggtgcccac caccttgccg
    19741 ctctggtcca gaaaatcccc ggcggggtag tgcttgccgg taaactgctc cataaagcgg
    19801 gcataatcgc cgtccggcac aaagcagata tcctgactgt cgtgcttttg ggcgttgata
    19861 aagctgtgct cctgcgcgat ctttcgcacc tcggtcttgt gcagtgcacc cagcggcaga
    19921 cggatatgcg ccagctgctc ctgcgtgaga ttatacagca catagctctg atccttgccc
    19981 tcgtccaagc cctttttcag cagccagcgg ccggtggctg cgtcctgctc cacccgggcg
    20041 tagtggccgg tgaccacata ctccatgccg tgttcttccg cccagtccag caggtggcgg
    20101 aacttcatat atttattgca gtcgatgcag gggttggggg taccgcccgc ctcgtagacg
    20161 cggataaatt tttcaatgat ctgtgcccgg aaatcggcgg tgaaatccag cacctgatac
    20221 ggcatatcca gcgcaaaggc cacctcggcg gcgtcctcga tatccttttc cgagcagcag
    20281 gtctggtagc cggactgtcc cagcgtttcg ttgtgggtaa gccgcatggt gatgccggtg
    20341 cagtcgtagc ctgcctgctg catcagacag gccgccaccg agctgtccac gccgccgctc
    20401 atggcaatga gggcgcgggg acggtttgca gggttctgtg tggtcatagg ttctcctttt
    20461 atgggttcaa catactaaag cagtagtata atactaccgc agcataaacc gcttgtcaag
    20521 acgctataat tttctgcgcc gcagccagca gcaccggttt ttcgttgggg tattctgcgc
    20581 ggatgacgcc gtccagcagc gtctccagca cccggcgcag cgcaggccct gccgggatgc
    20641 ccgccgccat caggtcgcgt ccgttcaccg ccagctggct cacccggcag catacgccgt
    20701 cggcttccag ctgccgcgcc cgctgcgccg caagggcgca attttgtgca tcctgcgggt
    20761 gcagcgccgc gcatagcgca cacagccgct ccacggtgca cagcccgtac cgccctaaaa
    20821 gccgccgaag gtgggtatca ctggcgcgtt ccggggcgtg tgcgggagtt tccccgagga
    20881 ccgtccgctg gggtgggacc ctgctgccgc aggcagtagg gcgggcgatg gaatggcctg
    20941 caacagcaac gactgccgcc tgcggcggaa acaaggagtt gctgttggga cagcggccag
    21001 caggatgcga gtgctgctca aggcacgaag catccgctgg gtgccgcaac tcgaactcgt
    21061 gtccgaggag aaagctcccg cacacgccct cccctgccgt ttcccgcacc agcacggcgg
    21121 tctcctcgat gcaggcgttg gagcagcgca gccgcttgag cacccggcgg gtgtcggcct
    21181 cgcccagagt gcccagcagc gcagcccagc gtaccggcag gttctcctcc cccgccgggc
    21241 aggcatccac caccggcttt gcggcttcaa gcgccgccgg ggtcaactcc ggcagcacca
    21301 ccgccagcac ggcgggttcc agatacgccc ccggctgcgg ggcaaccagc agctttgcca
    21361 gttcctcctg aatgcgctcg gcagagatgc agtccaaatg cggtgccagc tgccgcgccg
    21421 cccgggctgt ggctgcgtcc agcgtaaagc cgaatcttgc ggcaaagcgg tacagccgca
    21481 ggatgcgcag cgcgtcctcg gtaaaccgct gctgcggctc gcccaccgca cgcagcagac
    21541 cgttttgcag gtctttttgc ccgccaaagg ggtctaccag cccctcggct gcattatacg
    21601 ccatggcgtt gatggtaaaa tcccgccggg caagatcctc ccgcacgtcc ggtacgaact
    21661 gcaccgcgtc cgggtgacgg ccatcggtat agctgccctc ggtgcggaag gtggtagttt
    21721 cgtacagctg cccgccgtat ttgatggtga ccgtgccgtg ctgcaaaccg gtggggatgc
    21781 actgctctgt cccgaacagt tccatcacct gctgcggcag ggcactggtg cacaggtccc
    21841 agtcgtgggc ggtgcgcccc aaaaggctgt cccgcacgca gccgcctacg gcataggctg
    21901 cgtagcccgc cgcgtgcagg gcgtccagca gggcagctgc cccggggtca agtgtcagct
    21961 tcattcctcg ttctcctcgt aatgcagggt gatgcgtttg ccgtcaaagc cgcattctgc
    22021 cgccgggaag atgctttgcg cctgtgcaag atgctcctcc gggtcggtga ccatggggga
    22081 atagtgcacc agccacagcc gctttgcccc ggcttttgcc gccagcgc
//
