LOCUS       c00063_gnlPro..        13254 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LEDLNGCF_63.
ACCESSION   c00063_gnlPro..
VERSION     c00063_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 05:21:11
            Original ID  :: gnl|Prokka|LEDLNGCF_63
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13254
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13254
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2381:6624]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2382..6624
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..13254
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13254
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(61..852)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CbiA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_1"
                     /sec_met_domain="CbiA (E-value: 6.9e-28, bitscore: 87.1,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIKISKKATTIAIVNQKGGTGKTTTCENLGVGLAAEGKKVLLVDA
                     DPQGSLTISMGWQKPDELPVTLSTLMQKAMNDQCIPPGEGVLHHAEGVDLIPANIELAG
                     LEVALVNTMSREKMLKQVLDSAKQHYDYILLDCTPSLGMLTINALAAADTALIPVQAQY
                     LSAKGLEQLLQTINKVHRQINPKLKIEGILLTMTDNRTNYGRQIDTLIRQAYGKHIKVF
                     GQTIPHSVRAAEISAAGKSIFVHDPKGKVAEAYKSLTKTNY"
     CDS             complement(849..1256)
                     /locus_tag="ctg63_2"
                     /transl_table=11
                     /translation="MSETNLFYSEESDGMSKRAQLEEYFSQSLEVDLLLRLCPDDEDTI
                     YQIVDLLVDTCATNRKLLHIAGDDKPAEVVRSRFMKLNADHIKFVLKCLAENSSPIRNM
                     KQYLLASLYNAPTTMQLYYQNQTNHDLAKRG"
     CDS             complement(1413..1718)
                     /locus_tag="ctg63_3"
                     /transl_table=11
                     /translation="MTLDYFYGQTGELFSFYRIPKALFQEQRFQSLSTDAKTLYGILLD
                     RMSLSVKNGWLDKQNRVFIIFTIEDVKRALCCADNKATKLLRELEKFGLIERKRRG"
     CDS             complement(2382..3593)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_4"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.2e-14,
                     bitscore: 44.2, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVRDSRPPFAGLANLSEAQLHRLPTPCYLLDEAQLCRNGEILLG
                     VQQRTGCRILLAQKAFSNFNVYPVLAPYLAGTEASGLYESRLGREELPEKENHVFCAAY
                     RTDEFEELLQYADHIVFNSPSQLAKFGPAAKAAGKSIGLRINPECSTQEGHEIYDPCAP
                     GSRLGTTRAQWDAAVAAHPELPALLDGLHFHTLCEQDADALAVTLAAVEKKFADLLPRM
                     QWLNFGGGHHITRPGYALATLENCILSVRQKYGVQVYLEPGEAWALNAGYLVTTVLDTL
                     RNGDTSLAILDMSAACHTPDVIEMPYRPPLLDAGEAGEKAHTVRLGGPTCLAGDIIGDY
                     SFDTPLAEGDKLIFGDMAIYTTCKNNTFNGMPLPPIWLLGADGNCRELVHFGYQDFKMR
                     LGAQ"
     CDS             complement(3593..4852)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_5"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 3.6e-45, bitscore:
                     144.9, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.3e-33,
                     bitscore: 105.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKVLIIGCGGVASVAIHKCCQVPEVFTEICIASRTKAKCDKLAA
                     ELAPTTTTKITTAQVDADKVEEVIALIKAYQPDLVMNIALPYQDLTIMDACLACGVNYM
                     DTANYEPENTDDPEWRAIYEKRCKEAGFSAYFDYSWQWAYAKKFEEAGLTALLGSGFDP
                     GVTQAYCAYAKKHEFDTIDTIDILDCNGGDHGYAFATNFNPEINLREVSAPGSYWENGH
                     WVEIPAMSIKREYNFDQVGDKDMYLLHHEEIESLAKNIPEAKRIRFFMTFGQSYLDHMR
                     CLEDVGMLSTTPVNFNGQEIVPIQFLKALLPDPASLGPRTKGKTNIGCIFTGKKDGKDK
                     TYYIYNVCDHQECYKEVGSQAISYTTGVPAMCGALMLLTGKWTTKGVHTVEEFDPDPYL
                     DALDKYGLPRSESHNPALVD"
     CDS             complement(4892..5767)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_6"
                     /sec_met_domain="Arginase (E-value: 7.7e-78, bitscore:
                     251.5, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHPNVETFIGCDSSYRAASIVLYGAPYDSTTSYRPGARFGPAAIR
                     HESYGLETYSPYQNADLTDFDVFDSGDLELCFGSSELALADIEARAEEILKDGKFPLLL
                     GGEHLVTLGAVRAAVKKYPDLHIVHFDAHADLRDDYLGAKLSHACVLRRCHELVGDGHI
                     HQFCIRSGDRAEFEFAAQHTEMHKFDFTGLAELTAQLCESKVPVYLTIDLDCLDPSCFP
                     GTGTPEAGGVSFLQLLEAIRTVTKANIIGADLNELAPTLDTTGVSTATACKVLRETLIA
                     LDKGWPGFQV"
     CDS             complement(5767..6624)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_7"
                     /sec_met_domain="Spermine_synth (E-value: 7.8e-55,
                     bitscore: 175.0, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 3.1e-23,
                     bitscore: 71.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFWFSEFHTPDVKHSIRVNKQLYSKQSDYQRIDIFETPEFGRVL
                     TLDGNVMLTERDEFIYDEMIVHVPMAVHKEAKDILVIGAGDGGVVRELTRYDRVERIDL
                     VEMDPQVVEACRAYLPSNACRMDDRRVHIYFENALKYIRRCEEEYDLIIVDSSDPFGPS
                     EGLFTREFYGSCFNALKEDGIMVNQQGSPFYAEDASAMQRSHKRIASTFPISRVYQAHI
                     PTFAAGYWLFGFASKKYHPIDDLDAESWKALNMRTRYYTTKLHIGAFYLPAFLEEMLRE
                     VEEH"
     CDS             complement(6637..8103)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_8"
                     /sec_met_domain="OKR_DC_1_C (E-value: 4.3e-12, bitscore:
                     36.3, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 2.9e-123,
                     bitscore: 401.1, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNENKARSRLDQRRAPIYEALERFRQMRVVPFDVPGHKRGRGNPE
                     LTAFLGQQCVGVDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSSVQS
                     MVLTACKRGDEIILPRNVHRSVLNALVLCGAVPVYVNPEVDKRLGISLGMKREQVAKAI
                     KEHPNAVAVLVNNPTYYGICSDLRAIVKMAHDAGMLCLADEAHGTHFYFGGGLPVSAMA
                     AGADMASVSMHKSGGSLTQSSLLLIGPNVHPGYVRQIINLTQTTSGSYLLMSSLDISRR
                     NLALRGRQVFHQVADIAEYAREEINAVGGYYAFGKELCNGDSVFDFDTTKLSVHTLDIG
                     LAGIEVYDILRDEYDIQIEFGDIGNILAYLSIGDRPQEVERLVSALAEIKRRYRTDGSG
                     LLSQEYIDPVVAASPQEAFYAPKKSLPLRETEGMVCSEFVMCYPPGIPILAPGERITKE
                     ILNYIEYAKAKGCSMTGPEDPEILHLNVLA"
     CDS             8675..9418
                     /locus_tag="ctg63_9"
                     /transl_table=11
                     /translation="MEKEGVWMALPIAIVEDQTPDAQRLEELLQQQLPEAECTWFACGD
                     DFLRAAAEPGLYAVVFLDICMAGTNGIETARRLRQADPEVLIVFVTSSPEYVWDAFPVH
                     PFDYLLKPYQEEKFVHLAAELRRALRCKEPELEIRIARQSIQLPLRKVLYAIARNHYVL
                     ITTEDGEYRAMCSFAQIEEKLTARENFMSCNRGVIINMDKVLRFGEDCIEILDGTRLPV
                     RQKDKCTLLAHFTQYQFRHMRQELH"
     CDS             9436..10752
                     /locus_tag="ctg63_10"
                     /transl_table=11
                     /translation="MDLALFGRYFLDFALLYPSAFLCLASLWEKLRTPRRTACIAAGCI
                     TLLCIGCAALCAVFGLNSNSLLPAIVLVSFWLLRWRVTPEVTVSQTAFLFSISAVMMAV
                     CSLLSTLLNAQTEISNPQTVCLASTALLRLGLAAMLTVLFWFTAVQWSRWLLREYSGEA
                     FWQSAWPLPALYAVFLVYCMPLNPAVVLVGRLKIISVLAVSISLFGIFLLLYEMYRVAR
                     EFTRNARLDRENQLLAMESRRYMELQTYLDNTRRLRHDFRQHLHVIAGLTETGQLEELK
                     SYLHQYESELSEHRPSLCANAAVDALAGYYDHAAGQQSVPVEWKLALPRQLPMPEADLC
                     TILGNLLENALHASQKLPPEQRRVQVMAQMLSPAMLGLVVENRYDGMLKKQQGILRSTK
                     HEGTGIGLVSAETVVHKYNGNLHLETEEQIFRVNVLLNL"
     CDS             complement(10839..11078)
                     /locus_tag="ctg63_11"
                     /transl_table=11
                     /translation="MGFFAVLAASLFAVFIFTVFGGYSLLLWCQQSLWMVVPPALVLAV
                     LVWTFLKMDDKITALQKRVDELEAAQKSTEKLEK"
     CDS             complement(11098..11574)
                     /locus_tag="ctg63_12"
                     /transl_table=11
                     /translation="MIYDTLNNLPNYLGVSDNLDTVIEYIMARDITTLPAGRTRIDGDK
                     AVVTVSTVTPQTSDKALFQRHDNHITLETDLDGSELFEVSLAELTPTKPTDEAADTTVG
                     TAGTSIAGMLCEGRFALYLAGEPYKSGLKAQGCGKLKKAVFSIELDPDEEETEE"
     CDS             complement(11821..13254)
                     /locus_tag="ctg63_13"
                     /transl_table=11
                     /translation="EPISDSPAGIMVKSMLTGMAEYYSAELSEKVVRGMTENVLKGKYN
                     GGTIPIGFKVDEEKFFQVDPLKAPFVVEAFQRYNDGATMKELMNWLNDSGVTTNRNQKF
                     TYNSVQTLLTNKRYIGENHFKDIVMPDSIPAIVDKDLFEEVQQKIKKNSRAPARHKAED
                     DYLLTTKLFCGMCGAMMFGECGTGRNKIVHHYYKCATAKRFKTCKKKTVRKEWLEDLVI
                     AETMKLIQDDAVIDAIVAEVMELQEQENTTLPLLEKQMREVENGIENMLNAIQAGVLTN
                     STKSRLEKLEAQQKELEVRIAEEKIARPRLSENQVRFWLTRFRKLDPNVKSHRETLINT
                     FVNAVYLYDEKVLIAFNYKDGTKTISFNEIAAKDASEGNGSDLGCFAPPRTPVSNGYRS
                     FCFTCLEKGAARVDSNSCGAVAEDSAKTAQWAVFSSAARAIHTRPPRTPVSEPGTGVSV
                     LSALKRGCKGGFEQHRPAE"
ORIGIN
        1 aatgatgttt gtcatgggca gcggatggtt ggcggatttt ttcattttag ggcttgactt
       61 ttaatagtta gtcttcgtca gagatttata ggcttctgcc actttgcctt tcgggtcatg
      121 gacaaagatg ctcttacccg ccgcgctgat ttccgctgca cggacggagt ggggaatcgt
      181 ctgaccgaac actttgatgt gctttccgta tgcctgccgg atcagcgtgt cgatttgtcg
      241 gccatagttg gtgcggttat ctgtcatcgt cagcaggata ccttcgattt tcagctttgg
      301 gttgatctgc cgatgcacct tgttgatggt ctgcaaaagc tgttccagac ctttcgcgga
      361 aaggtactgt gcctgtacgg gtatcagagc agtgtctgcc gccgccagcg cgttaatggt
      421 cagcatccca agggagggag tgcagtccaa cagaatatag tcatagtgct gctttgcact
      481 gtccaagact tgcttcagca ttttttcccg gctcatggta ttgacaaggg caacttccag
      541 ccctgccagc tcaatgttgg ccgggatgag gtctacaccc tctgcatggt gcagcacacc
      601 ttcaccgggc ggaatgcact ggtcgttcat ggctttctgc atcagggtag aaagagtaac
      661 gggcagttcg tccggcttct gccagcccat actaatggtg agtgaaccct gcgggtcagc
      721 gtctacaagt aggaccttct taccctcggc ggcaaggcca acacccagat tttcacaggt
      781 tgttgttttg ccagtgcctc ccttttggtt gacaatggca atcgtggttg cttttttgga
      841 aatttttatc acccccgttt cgctaaatcg tggttggtct gattctgata gtaaagctgc
      901 atggtggtcg gtgcgttgta cagagaagcg agcaggtatt gcttcatgtt cctgattggg
      961 ctgctgttct ctgcaaggca cttcaacaca aatttgatgt ggtcggcgtt cagcttcata
     1021 aatcggctac gtaccacctc ggcgggctta tcgtccccgg cgatgtgcag tagcttgcgg
     1081 ttggtagcac aggtgtccac cagcaaatct acgatctgat agatggtgtc ctcatcatcc
     1141 gggcagagcc ggagcagaag gtctacctcc aaagactgcg aaaaatattc ttccagttgg
     1201 gcgcgcttac tcatcccatc cgattcttcg gaatagaaga gattagtctc actcatttca
     1261 gtatcattct ctttagtctt attacaccgt gattttgcag ggtcttgaca cgcgattttg
     1321 aagccacaag aatcgtcatt atcacgattc ttgacactct cttttgaaga ttctgccgaa
     1381 aagtttttca catataccaa acttggcttt ccttaccctc ggcgttttcg ttcaatcaga
     1441 ccaaactttt caagttcccg gagcagcttg gttgctttgt tgtctgcgca acacaatgcc
     1501 ctcttgacat cctcgattgt gaagatgatg aacacccggt tttgcttgtc cagccagccg
     1561 tttttcaccg acaggctcat gcggtccagc aggataccat acagggtttt ggcatccgtg
     1621 gacaggctct ggaaccgctg ctcctgaaaa agagcctttg gaatgcggta gaaggagaaa
     1681 agctctccag tctgtccgta gaagtagtca agggtcatgc ggttggttca tggataaaaa
     1741 acagcgataa tacatcggca tcgttgagaa aacctccttg tcaatacttt ggggggaaaa
     1801 taaaaagcgc aactttgatg tgtaaaatca aaattgcgct aagtaagctg tcagaaaaaa
     1861 cttttctcgt aaatgacctt ctctctgagc aaaacccatt gacacacttg aaaattgggt
     1921 ggtaaaattg ccttgtaggc ggagcatgat tcctggaagc aggatgcaac tgtgaacctt
     1981 tttggtggat agaacgtatc aacgcgatat taagcctgtc cccgcacttt cgtgtggggg
     2041 gtgtgtttcg ataccgttcg ggagagcgct tgcatggcat gcaagaggtc accggttcga
     2101 tcccggtaat ctccaccaga aacaaaaagc actacacaga aatgtgtggt gcttttttgt
     2161 tgacgccaaa cgagtgaggg tttagctcag ctgggagagc gccgtgcatg gactgcaaga
     2221 gggtcaccgt gatcagaatc ggcccggtaa tctccaccag aatgaaagca ctacacggaa
     2281 acgtgtggtg cttttttgtt ttatctgccg ttcaccttac gtcccctttc ataaaaaaag
     2341 cgtttgtcgc agcccgcagg ccgtgacaaa cgctttttat tttactgtgc gcccaagcgc
     2401 attttgaagt cctgatagcc aaagtgcacc agctcccggc aattgccgtc tgcgcccagc
     2461 agccagatag gcggcagggg catcccattg aaggtgttgt tcttgcaggt ggtgtagatg
     2521 gccatatcgc cgaaaatgag cttatcgccc tcggcaaggg gggtgtcaaa gctgtaatcc
     2581 ccgatgatat cccccgcaag gcaggtgggg ccgcccagcc ggacggtgtg cgccttctct
     2641 cctgcctcgc cggcgtccag cagcggcggg cggtagggca tctcgatgac atccggggtg
     2701 tggcaggctg cggacatatc cagaatggca agactggtat ccccgttgcg cagggtgtcc
     2761 agcacggtag tgaccagata gcctgcattc agcgcccaag cctcgccggg ctccaaatac
     2821 acctgtacgc cgtacttctg ccgcaccgag aggatgcagt tttccagcgt agcaagggca
     2881 tagcccgggc gggtgatgtg gtgtcccccg ccgaaattga gccactgcat tctgggcagc
     2941 aggtcggcaa actttttctc cactgcggcc agcgttaccg ccagcgcatc ggcgtcctgc
     3001 tcgcacaggg tatggaagtg cagaccgtcc aacagggcgg gcagctccgg gtgcgctgcc
     3061 acagcggcgt cccactgagc acgggtggtg cccagacggc tgccgggggc gcaggggtcg
     3121 taaatttcat gaccctcctg cgtggagcac tccgggttga tgcgcagacc gatgcttttg
     3181 cccgccgcct ttgccgccgg gccgaacttt gccagctggc tgggcgagtt gaacacgatg
     3241 tggtcggcgt attgcagcaa ttcctcaaac tcatctgtcc ggtaggcggc gcagaacaca
     3301 tggttctcct tctccggcag ctcttccctg cccaagcggc tctcgtacag gccgctggcc
     3361 tcggtacctg ccagataggg tgccagcacc gggtagacgt taaagttgga aaaagccttc
     3421 tgcgccagca ggatgcggca gccggtgcgc tgctgcacac ccagcaggat ctcgccgttg
     3481 cggcacagtt gggcttcgtc cagcagatag cagggggtgg gcaggcggtg cagctgcgcc
     3541 tcggacaggt ttgccagccc cgcaaagggc gggcggctgt cgcgcacccg catcagtcca
     3601 ccagagccgg gttatggctc tcggagcggg gcaggccgta cttatccagt gcatccagat
     3661 acggatcggg atcaaactcc tcgacagtgt gcacgccctt ggtggtccac ttgccggtga
     3721 gcagcatcag ggcaccgcac atggcgggca cgccggtggt gtagctgata gcctgagagc
     3781 ccacttcctt gtagcactcc tgatggtcgc agacgttgta gatatagtag gtcttatcct
     3841 tgccgtcctt tttgccggta aagatgcagc cgatgttggt cttgcctttg gtacgggggc
     3901 caaggctggc ggggtccggc agcagagcct tgaggaactg gatgggcacg atctcctgtc
     3961 cgttgaagtt gacaggggtg gtggacagca tgcccacgtc ctccagacaa cgcatgtggt
     4021 ccagatagct ctggccaaag gtcatgaaga agcggatgcg ctttgcctcc gggatgttct
     4081 ttgccagaga ctcgatctcc tcgtggtgca gcaggtacat atccttgtcg cccacctgat
     4141 cgaagttgta ctcccgcttg atgctcatag ccgggatctc tacccagtgg ccgttctccc
     4201 agtagctgcc gggagcggac acctcgcgca ggttgatctc cgggttaaag ttagtggcaa
     4261 aggcatagcc gtggtcgccg ccgttgcagt ccagaatatc gatggtgtca atggtatcga
     4321 actcgtgctt tttggcatag gcacagtaag cctgggtcac acccgggtcg aagccgctgc
     4381 ccagcagggc ggtcaggccg gcttcctcga actttttggc gtaggcccac tgccagctgt
     4441 aatcaaagta ggcagagaag ccggcctcct tgcagcgctt ctcgtagatg gcgcgccact
     4501 ccgggtcatc ggtgttctcg ggctcgtagt tggcggtgtc catgtagttg acgccgcagg
     4561 caaggcaggc gtccatgatg gtcagatcct gataaggcag ggcgatgttc atcacgaggt
     4621 cgggctggta agccttgatg agggcgatga cctcctccac cttgtctgcg tccacctgtg
     4681 cggtggtgat cttggtagta gtggtgggag ccagctcagc agccagctta tcgcactttg
     4741 ccttggtacg gctggcgatg cagatctcgg tgaacacctc gggcacctgg cagcacttat
     4801 ggatggcaac agaggccacg ccgccgcagc cgatgatcag aactttgctc atgtcggtta
     4861 ctcctttatc tgtaaaatgg taggttcgta tttatacctg aaagcccggc cagcccttgt
     4921 ccagcgcgat cagggtctcg cgcagcacct tgcaggcggt ggcggtggaa acgccggtgg
     4981 tgtccagcgt gggggcaagc tcgttcaggt ctgcaccgat gatgttggcc ttggtcacag
     5041 tgcggatggc ctccagcagc tgcaaaaagc ttacgccgcc agcctccggg gtaccggtgc
     5101 ccgggaagca ggaggggtca aggcagtcca gatcgatggt caggtacacc ggcaccttgc
     5161 tctcgcacag ctgtgcggtc agctcggcaa ggccggtaaa atcgaacttg tgcatctcgg
     5221 tgtgctgggc agcaaactca aattctgccc ggtcgccgct gcggatgcag aactgatgga
     5281 tgtggccatc ccctaccagc tcgtggcagc ggcgcagcac acaagcgtgg ctgagcttcg
     5341 cgcccagata gtcgtcccgc aggtcggcgt gggcgtcgaa atggacgatg tgcaggtcgg
     5401 ggtatttctt caccgcagca cgcaccgcac ccagcgtgac caaatgctcg ccacccagca
     5461 gcagcgggaa cttgccgtcc ttcaaaattt cctctgcccg ggcctcgata tcggccagtg
     5521 ccagctcgct ggagccgaag cacagctcca gatcgccgct gtcgaacaca tcaaaatcgg
     5581 tcaggtcggc gttctggtaa gggctgtaag tctccagacc gtagctctcg tgccggatgg
     5641 ccgccgggcc gaaccgtgca ccggggcggt agctggtggt ggaatcgtaa ggcgcaccgt
     5701 acagcacgat gctggcggcg cggtagctgc tgtcgcagcc gataaaggtc tcaacgttgg
     5761 ggtgcatcag tgttcctcca cttcccgcag catctcctcc agaaaagccg gcaggtagaa
     5821 tgctccgata tgcagtttgg tggtgtagta gcgggtgcgc atattcagcg ccttccacga
     5881 ttcagcgtcc agatcatcga tgggatggta ttttttgctt gcaaagccga acagccagta
     5941 ccctgccgca aaggtgggga tatgcgcctg atacacccgg ctgatgggga aggtggatgc
     6001 aatgcgcttg tggctgcgct gcatggcgct ggcgtcctcg gcgtagaagg ggctgccctg
     6061 ctggttgacc atgatgccgt cctctttcag ggcgttgaag cagctgccgt agaactcgcg
     6121 ggtgaacaga ccctcagagg ggccgaaggg gtcggaggag tccacaatga taaggtcgta
     6181 ctcctcctcg cagcggcgga tatacttcaa ggcattctca aaatagatat gcacccgacg
     6241 gtcatccata cggcaggcat tgctgggtag gtaagcgcgg caggcctcca ccacctgcgg
     6301 gtccatctcc acaaggtcga tgcgctccac acggtcgtag cgggtcagct cccgcaccac
     6361 gccgccgtct ccggcaccga tgaccagaat atccttggct tccttgtgca ccgccatggg
     6421 cacatggacg atcatttcat cgtagatgaa ctcatcgcgc tcggtcagca tcacgttgcc
     6481 gtccagcgtg agcacccggc cgaactccgg ggtctcaaag atatcaatgc gctgataatc
     6541 gctctgcttg gagtagagct gcttgttcac acgaatgctg tgcttcacat ccggggtgtg
     6601 aaactctgaa aaccaaaatt ccatctcttt ccctccttat gccagaacat tcaggtgcaa
     6661 aatttcgggg tcctccgggc cggtcatgct gcagcccttg gccttggcgt actcgatgta
     6721 gttcaggatc tccttggtga tgcgctcgcc gggtgcaagg atggggatgc ccgggggata
     6781 gcacatgacg aactcgctgc acaccatgcc ctcggtctcc cgcaggggca ggctcttttt
     6841 gggggcatag aaggcctcct gcgggctggc agccaccacg gggtcgatgt attcctgact
     6901 cagcagaccc gagccatcgg tgcggtagcg gcgcttgatc tcggccagcg cactgaccag
     6961 acgctccacc tcctgcgggc ggtcgccgat ggacaggtag gcaaggatgt tgccgatatc
     7021 gccgaactcg atctgaatgt catactcgtc ccgcaggatg tcgtagacct cgatgccggc
     7081 aagaccaata tccagcgtat ggacgctgag cttggtggtg tcaaagtcaa aaacagaatc
     7141 gccgttgcac agctccttgc caaaggcgta gtaaccgcct acggcgttga tctcctcgcg
     7201 ggcgtactcg gcaatgtctg ccacctgatg gaacacctgc cgtccccgca gcgccagatt
     7261 gcggcgggag atatccagac tggacatcag caggtagctg ccggaggtag tctgggtcag
     7321 gttgatgatc tggcgcacat agcccgggtg cacgttggga ccgatgagca gcaggctgga
     7381 ctgggtcagg ctgccgccgc ttttgtgcat ggagaccgag gccatatccg cgcccgccgc
     7441 catggcagaa accggcaggc cgccgccaaa gtagaagtgg gtgccgtggg cttcatccgc
     7501 aaggcagagc ataccggcgt cgtgcgccat ttttacgatg gcacgcaggt cggagcagat
     7561 gccgtagtag gtggggttat tcaccagcac agccacagcg ttggggtgct ccttgatggc
     7621 ctttgccacc tgctcccgct tcatgcccag cgagatgccc aggcgcttat ccacctccgg
     7681 gttcacatac accggcaccg cgccgcacag caccagcgcg ttcagcacgc tgcggtgcac
     7741 gttgcggggc agaatgatct catcgccccg cttgcaggcg gtaagtacca tgctctgcac
     7801 gctgctggtg gtgccgccca ccattaaaaa ggcgtgtgcc gcgccaaatg catcagcggc
     7861 aagctcctca gcttcccgga tgaccgacac cgggtggcaa aggttatcca gcggcttcat
     7921 actgttcacg tccacgccca cgcactgctg acccagaaaa gcggtcagtt ccgggttgcc
     7981 gcggcctcgc ttgtggccgg gcacgtcaaa aggcaccacc cgcatctgcc ggaaccgctc
     8041 cagcgcctcg taaatgggcg cacggcgctg atccagccgg gaacgcgctt tgttctcgtt
     8101 catcatttcc tccgtccctg ttcttctttt tgcacaacaa aaaagcgcag acactgcaca
     8161 aatatgcaga cctgcgcttg gagcagcttt ttccgcgctg ataaagcacc cagccgtaag
     8221 tgccggtgct gcgcgttatt cgcgatccaa aaagacgggg tgatgagagt ctatatagca
     8281 actacacttt tactactctt attgaccgtt tcacaagtct gcgcataggc tgcgcaattt
     8341 catggttgta aaggaaccaa cttataaaat ttgagcttca aactcaatca ataatggcag
     8401 cttgcgccgc cggtcggcag tggacccggc tgtccgtatg gccttagccc cgtttgggcg
     8461 gtcccgagta aattgctttg aaaagactct gcaaggcggc gtctctcaaa atcaacaaaa
     8521 gaataacatg attcgccccg tctgtcaacc aaaacttttt ggcagtcgcc cgctgcagat
     8581 gcgcagggcg gcgctcggcg cgcaaaatgg agcgttttgt gcaaaaaagc agatgccctt
     8641 cccgccgcag tatgctataa taaaggaaca atgaatggag aaagagggtg tatggatggc
     8701 actgccaatc gccatcgtag aggatcagac cccggacgcc cagcggctgg aggagttgct
     8761 gcaacagcag ctgcccgaag ccgagtgcac atggtttgcc tgcggggatg attttctccg
     8821 tgccgcagca gagcccggct tatacgccgt ggtgtttctg gatatctgca tggcgggcac
     8881 caacggcatc gagaccgccc gccgactgcg gcaggccgac ccggaggtgc tgatcgtatt
     8941 cgtgacctcc tcgccggaat atgtatggga tgcctttccg gtgcacccct tcgattacct
     9001 gctcaaaccc tatcaggagg aaaaattcgt gcaccttgcc gccgagctgc ggcgggcgct
     9061 gcgttgtaag gagccggaac tggagattcg cattgcccgc caaagcattc agctgccgct
     9121 gcgcaaggtg ctgtatgcca ttgcccggaa ccactacgtc cttatcacca ccgaggatgg
     9181 tgagtaccgc gccatgtgca gctttgcgca gatcgaagaa aagcttaccg cacgggaaaa
     9241 ctttatgagc tgcaaccgag gcgttatcat caacatggac aaggtgctgc ggttcgggga
     9301 ggactgcatc gagatcttgg acggcacccg cctgccggta cggcagaagg ataaatgcac
     9361 tctgcttgcc cactttacac aataccagtt ccgccacatg cggcaggagc tgcactgagg
     9421 aaaggagcag ccgccatgga tcttgctctg ttcggccgtt attttctgga ttttgcgctg
     9481 ctgtatccca gcgcgtttct gtgtctggca tccctatggg aaaagctgcg cacccccagg
     9541 cgcaccgcct gcatcgctgc cggatgcatc accctgctgt gcatcggctg cgccgcgctc
     9601 tgcgccgtgt tcgggctgaa cagcaattct ctcctgcccg ccatcgtgct ggtctccttc
     9661 tggctgctgc gctggcgggt aacgccggaa gtgaccgtaa gccagaccgc gtttctgttt
     9721 tccatctctg ccgtgatgat ggcggtgtgt tccctgctgt cgacgctgct caacgcccag
     9781 accgagatct ccaacccaca gaccgtctgc cttgcctcca cggcgctgct gcggctgggc
     9841 cttgccgcga tgctcaccgt gctgttctgg ttcaccgccg tgcagtggag ccggtggctg
     9901 ctgcgggagt acagcggtga agccttctgg caatctgcgt ggccgctgcc cgccctctat
     9961 gccgtttttc tggtatactg tatgccgctg aaccccgccg tggtgctggt cgggcggctg
    10021 aagatcatct cggtgctggc ggtatccatc tcgctgttcg gcatctttct gctgctatac
    10081 gagatgtacc gcgttgcccg ggagtttacc cgcaatgccc ggctggaccg ggaaaaccag
    10141 ctgctggcca tggaatcccg ccggtacatg gagttacaga cctatctgga caacacccgc
    10201 cgtctgcggc acgacttccg gcagcatctg catgtgattg ccggactgac cgagaccggg
    10261 cagctggagg agctgaaaag ctatctgcac cagtatgaaa gcgagctcag cgagcaccgc
    10321 cccagcctgt gcgccaacgc cgccgtggat gcactggccg gatattacga ccatgcagcc
    10381 gggcagcaga gcgttcctgt ggagtggaag ctggcactgc ctcggcagct tcccatgccg
    10441 gaggccgacc tgtgcaccat tctgggcaat ctgctggaaa acgccctgca cgccagccag
    10501 aagctgccgc cggagcagcg ccgggtgcag gtgatggcgc agatgctcag tcccgccatg
    10561 ctggggcttg tggtggagaa ccgttacgac ggcatgctga aaaaacagca gggcatcctg
    10621 cgctccacca agcacgaggg caccggcatc gggctggtat ctgccgagac ggtagtgcac
    10681 aaatataacg gcaatctgca tctggagacc gaggagcaga tcttccgggt gaatgttctg
    10741 ttaaatctgt aaccaccggc aggccaacgt gaaagcgttc acaaaaaaag cagcgccgtc
    10801 ctttgcagag aggtttctct acgaagggcg gcgctgtatt atttttcaag cttctccgtg
    10861 cttttttgtg cggcttccag ctcgtccacc cgcttttgca gggcggtgat cttatcgtcc
    10921 attttcaaaa atgtccagac cagaacggcc agcaccagcg cgggaggaac gaccatccac
    10981 agggactgct gacaccagag cagcagcgaa tagccgccga atacagtaaa aataaatacg
    11041 gcaaacagac ttgcagccag tacagcaaaa aatcccatac agaaagtctc ctttcagtta
    11101 ttcttccgtt tcttcctcgt ccgggtccag ctcaatgctg aacacggctt ttttcagctt
    11161 tccgcagccc tgcgccttca ggccggattt atacggttcc cctgccagat acaaggcaaa
    11221 gcgtccctcg cacagcattc cggcaatgct ggtaccggca gtgcctacgg tggtgtcggc
    11281 ggcttcatcg gttggcttgg tgggcgtcag ctccgcaagg cttacctcaa acagctcact
    11341 gccgtccaag tcagtctcca gcgtaatgtg attgtcgtgc cgctggaaca gtgccttgtc
    11401 ggaggtctgg ggcgtgacgg tgctcacggt gaccaccgcc ttgtccccat cgatgcgggt
    11461 gcgcccggca ggcagggtgg tgatatcccg cgccatgatg tactcgatca cggtgtccag
    11521 attgtcgctt acgcccagat agttgggcag gttgttcagg gtatcgtaga tcatagaaaa
    11581 agtcctccgt ctgtgttgtt tcagttacct gtatggtatc acaggtcagg gacagatgca
    11641 atatgtgtgc gggcagatgt cgcgagccgc gcagaaaagg aacccgggtc gcggctccca
    11701 gcggctgcat cgtgccttgg gcggcacgcg catcctgctg gccgcagccc caacagctcc
    11761 tccctgtttc tgccgctggc agcggtcgtc gctgttgcac aggggctttc ccccgccgga
    11821 ctattcggcg ggtcgatgct gttcgaatcc acccttgcag ccccttttca aggcagataa
    11881 aacagaaact ccagtacccg gttcggatac tggagtcctt ggtgggcgcg tgtggattgc
    11941 gcgagccgcg ctgctaaaaa cagcccactg ggctgttttt gcgctgtctt ctgcgacagc
    12001 gccgcagctg ttcgaatcca cccttgcagc ccctttttca aggcaggtaa aacagaaact
    12061 ccggtaccca ttggataccg gagttcttgg tggagcgaag caacccaaat ccgaaccatt
    12121 gccctctgag gcatctttgg cggcaatttc attgaaagag atggtttttg tgccgtcttt
    12181 gtagttgaat gcaatcaaaa ctttttcatc ataaagataa acggcgttca cgaacgtgtt
    12241 gataagcgtc tcccggtggc ttttcacgtt cgggtcgagt ttgcggaacc gggtcagcca
    12301 gaaacgaacc tgattttcgc ttaaccgtgg ccgagcgatt ttttcttcgg cgatccgaac
    12361 ctcaagttct ttctgctggg cttccagctt ttccaaacgc gacttggtgg aattggtcag
    12421 cacaccagct tgaatggcgt tcagcatatt ttcaatgccg ttctccacct cgcgcatctg
    12481 cttttccagc aaagggagtg tggtgttttc ctgttcctgc aactccatga cctctgcaac
    12541 gatggcatca atcacggcat cgtcttgaat cagcttcatg gtttcagcta tgaccaaatc
    12601 ttccagccac tctttacgga cggtcttttt cttgcaggtc ttgaaacgct tcgcggtggc
    12661 gcacttataa taatgatgaa cgatcttgtt tctacccgta ccgcactcgc cgaacatcat
    12721 cgcgccgcac attccgcaga acagcttggt ggtgagcaag taatcgtcct cggccttgtg
    12781 acgggcagga gcgcggctgt tcttcttgat tttttgctgc acttcttcaa acaagtcctt
    12841 gtccacgatg gccgggatac tgtcgggcat cacaatgtcc ttgaagtggt tttctccgat
    12901 gtaccgtttg ttcgtcaaca gcgtctgaac actgttgtag gtgaacttct ggttgcggtt
    12961 ggtagtcaca ccgctgtcgt tcagccagtt catcagctcc ttcatggtcg caccatcgtt
    13021 gtaccgctgg aaggcttcta ccacaaaggg agctttcagc gggtcgactt gaaagaactt
    13081 ctcctcatcc accttaaacc caatgggaat cgtgccgccg ttgtacttgc ccttcagaac
    13141 attctcggtc atgccgcgca caactttttc agaaagttct gccgagtagt attcagccat
    13201 gccggtgagc atactcttga ccatgatacc cgcagggctg tcagagatag gctc
//
