LOCUS       c00014_gnlPro..        11290 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DACFKGJC_14.
ACCESSION   c00014_gnlPro..
VERSION     c00014_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 09:08:39
            Original ID  :: gnl|Prokka|DACFKGJC_14
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11290
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11290
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[860:11127]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      861..11127
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..11290
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11290
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(88..606)
                     /locus_tag="ctg14_1"
                     /transl_table=11
                     /translation="MRLIKNTTELIGIKDQNIKISLVFETDTHIEIQAKLDYPAPSCPH
                     CHGKMIKYDFQKPSKIPLLEQAGTPTLLRLKKRRFQCKNCRRVTVAETSIVEKNCQISN
                     LVRQKVTQLLTEKMSLTDIARKLRVSTSTVYRKLDQFTFKEHYDKLPTVMSWDEFGFKK
                     GEFAFVAQN"
     CDS             861..2345
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_2"
                     /sec_met_domain="PALP (E-value: 1.8e-17, bitscore: 52.8,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVYQSTRDENNKVTASQAILQGLATDGGLFTPLSTPEVTLNFD
                     QLKDASYQEVAKLVLSAFLDDFTEEELDYCITNAYDDKFDTAAIAPVVKLKNHYNLELF
                     HGSTIAFKDMALSILPYLLTTSAKKQGVDNKIVILTATSGDTGKAAMAGFADVPGTEII
                     VFYPKDGVSKIQELQMTTQTGANTHVIAIDGNFDDAQTDVKRMFNDVDLREKLLAHHTQ
                     FSSANSMNVGRLVPQVVYYVYAYAQLVKAGHIQNGDKVNFTVPTGNFGNILAAYYAHQI
                     GVPVGKLICASNENNVLTDFFATGTYDKKRDFKVTTSPSMDILVSSNLERLIFHLLGND
                     ATKTKELMDALVTKGEYTLADADKDILDLFAAGFATEDETAAEIKRVYDEDKYIEDPHT
                     AVASAVYEAYVQKTDDHTPTVIASTASPYKFPRVAVSAVTGKDSGDDFKAVEDLHQLSG
                     VAIPAAVDGLEHAEVRHKTVVAAADMQKAVESYLGV"
     CDS             2406..3692
                     /locus_tag="ctg14_3"
                     /transl_table=11
                     /translation="MTETKKILNIALPAMAENLLQMLMGVVDSYLVAQVGIVAISGVSV
                     ANNIITIYQAIFIALGASSASVIARSLGKGDVKATNRDTWDAIIITLALSLILGLLSIF
                     GGGAILNLLGTEQSVTQAGSLYLALVGGGVVFLALMTTFGNILRAKGRPRISMVVSLLT
                     NVLNAILSSLAIFVGHWGIVGVATATVFSRLVGTVILWQAMKLDVKQLEITKPFNRELL
                     GIALPAAGERLMMRAGDVVIVAIIVTFGTAVVGGNAIGENLTQFNYMPGMGVATATVIL
                     VANSLGRGDKTQMKRIIRESYWISTFLMVLVSGSILLFGQGLSGLFTDNKAAIAASQVV
                     ILYSFLGNPVTSGTLVYTAVWQGLGKAKMPFYATTIGMWIIRIFSGYFLGVSLGMGLAG
                     VWIATVVDNVWRAIFLYVMYRRYLVKRKF"
     CDS             3804..4169
                     /locus_tag="ctg14_4"
                     /transl_table=11
                     /translation="MTVKINTKDGQIELSDDVIATVVGGSATEIFGVVGMASKSAIRDN
                     FQALLGKENYAKGVVVKSTDAGITVDVYTVMSYGVKISEVSKNIQERVKFNLENQLGIK
                     AETVNVYVQNIKVVGEN"
     CDS             4169..5836
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dak2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_5"
                     /sec_met_domain="Dak2 (E-value: 2.2e-44, bitscore: 140.7,
                     seeds: 138, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSKITTSLLQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNMG
                     MTMDNGAKAVADQSASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKDKTELD
                     GQDLAHAFQAGVEVAYKAVMKPVEGTILTVSRGAASAAIKKAESTNDAVEVMRAALDGA
                     KAALAKTPEMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFQATPATMTEMI
                     NAEHHKSVAGHVATEDITFGYCTEIMIGLKQGPTYVKDFDYEEFQNYLSNLGDSLLVVN
                     DDEIVKVHVHTEDPGLVMQEGLKYGALVKVKVDNMRNQHDAQVQKEEAIQAAPSAPKDF
                     ALIAVVAGDGLADIFKSQGVDYVISGGQTMNPSTEDIVKAIEQVNAKNVIILPNNKNIF
                     MAAQSAAEVVDVNAAVVETRTVPQGFTSLLAFDPSQSIEANVEAMTASLSDVTSGSVTL
                     AVRDTTIDGLEIHENDILGMVDGKILVSTPDMDQALLDTFDKMIDEDSEIVMIYVGEEG
                     NQEQAQALAEKLEEAHEGIEVEIFQGDQPVYPYLFSVE"
     CDS             6006..7727
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_6"
                     /sec_met_domain="ILVD_EDD (E-value: 2.5e-225, bitscore:
                     738.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDMIKVGVDKAPARGLLYATGQVKSAKDMQKPFIAICNSYIDI
                     VPGHVHLRELADIAKEAIREAGGIPFEFNTIGVDDGIAMGHIGMRYSLPSRELIADSAE
                     TVINAHWFDGVFYIPNCDKITPGMILAAMRTNVPAVFCSGGPMKGGVDMTGHQATLSSL
                     FEAVGTYQAGDMSKEELDYLEKNACPTCGSCSGMFTANSMNCLMEVLGLALPGNGTILA
                     VSDERRELVRQAATKLMDNIKNNVRPRDIVTKEAIDDAFALDMAMGGSTNTVLHTLAIA
                     REAGIDYDLKDINEIAKKTPYLSKIAPSSVYTMHDVHEAGGVPAIINQLIKKGAIKGDR
                     ITVTGKTLKENVAGAEIKNEEIIHPIEHPISPVGGLSILYGNIAQDGAVIKVGGVDPSV
                     KTFRGKAICCDSQDQALELIDNGTVKKGHVVVIRYEGPQGGPGMPEMLAPTSKIVGRGL
                     GKDVALITDGRFSGATRGIAIGHVSPEAAEGGNIALIEDGDEIVIDLPNRTLDLLVDDV
                     TLEERRKHLKPFKSKISSGWLRRYTAFAKSANVGGTLMSDEEFEERKAERQAQEKN"
     CDS             7861..9561
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1e-48, bitscore:
                     154.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKKIELEEARSGADLILDTLLELGISTIFGYPGGAVLPLYDAIYK
                     NDKINHILSRHEQGSLHEAEGYAKSTGKLGVALVTSGPGATNAITGIADAMSDSVPLLV
                     FTGQVATSGIGKDAFQEADIVGITMPITKYNYQIRDTADIPRIIREAVHIATTGRPGPV
                     VIDLPKDVVAKETAFINDPEINLPSYQPTLRPNEMQIKKILKQLGKAKKPVIVAGGGVS
                     YSESAKELVAFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSYAANIAMTDADFMI
                     AIGCRFDDRLTGNPKTFAKNAKVVHIDVDPAEIGKIIAVDLPVVGDAKQALEMLLAEPV
                     VQNNTEKWIEKVTKDKERVRSYDKKERMVQPQAVIERIGELTKGDAVVVTDVGQHQMWT
                     AQYYPYQNERQLVTSGGLGTMGFGVPAAIGAKIANPDKEVILFVGDGGFQMTNQELAIL
                     NIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAYGIKSYKFDN
                     PETIDQDLEVIKEDVPMFIEVDISRKEHVLPIVPAGKSNHEMLGVKFNA"
     CDS             9554..10030
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_8"
                     /sec_met_domain="ALS_ss_C (E-value: 3.2e-29, bitscore:
                     90.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGASEDPNVSR
                     ITIIIDVNSQNEVEQIIKQLNRQIDVIRIRDITDQPHLEREVILVKVSAPTSKRAEILA
                     IIQPFRASVVDVAPSSITIQMTGDAEKSEALLRVIRPYGIKNIARTGATGFTRD"
     CDS             10105..11127
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_9"
                     /sec_met_domain="IlvN (E-value: 8.7e-81, bitscore: 258.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.6e-63, bitscore: 202.6,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGHDVI
                     IGVRPGKSFDKAKEDGFDTYTVAEATKLADIIMVLAPDEIQKDIYKDEIEPNLSAGKAL
                     GFAHGFNIHFEFIKVPKDVDVFMVAPKGPGHLVRRTYTEGFGVPALYAVYQDATGNAKD
                     IAMDWAKGIGSARVGLLVTTFKEETEEDLFGEQAVLMGGLTHLIEAGFEVLTEAGYAPQ
                     LAYFEVLHEMKLIVDLIYEGGFKKMRQSCSNTAEFGDFVTGPRVIGPEVKENMKAALAD
                     IQSGKFAREFVEDHDAGFPRLKAYRKEAEELEIEKIGAELRKAMPFVGQNDDDAFKIYN
                     "
ORIGIN
        1 tcggactttc aatggatact tcaaaaagta gtttcgtata gtggtttggc gacgattatc
       61 aaggatggtt atgagttcgt ttgtctctta attctgggct acaaaagcga attccccttt
      121 cttgaaccca aactcatccc aggacataac agtagggagc ttgtcataat gttccttgaa
      181 agtaaactgg tcgagcttac gatagacagt ggacgtcgac acacgaagct ttctggcaat
      241 atcagttagt gacatcttct cagttagtag ttgtgtaacc ttttgtcgga caaggttgga
      301 gatttgacag tttttctcaa cgattgatgt ctcagctacc gtgactctcc tacaattttt
      361 acactggaag cggcgtttct tcagacgtag tagtgttgga gttcccgctt gttcgagaag
      421 agggatttta gaaggctttt gaaagtcgta cttgatcatt tttccatggc aatgaggaca
      481 tgatggtgca ggataatcga gttttgcttg aatctctata tgagtgtcag tttcaaaaac
      541 aagtgaaatc ttgatgtttt ggtctttaat tccgattaat tctgtggtat tcttaataag
      601 tctcataagt tcttcctaat gatggtttgg ttgcttttca ttatagttct tatgggactt
      661 tttgtctgca ttcaaaaagc tctataatct ctacagtgat tttacccact acagaaatta
      721 tagagccatt ttttcatgtc tttgagagga gaaaataggg tgatatccga atgatttttt
      781 cacaagtcac aaaacgtgta gaaatattct gacaattatg ttacaataga gccacagact
      841 atctaaaaag aggatttacc atgacacttg tataccaatc aacacgtgac gaaaataata
      901 aagtaacagc tagtcaggct attcttcaag gtttggcaac agatggtggc ttgttcacac
      961 cgttgtcaac gcctgaggtt actttgaact ttgatcaatt gaaagatgct tcttaccaag
     1021 aagttgctaa attagtcttg tcagctttct tggatgattt tactgaagag gaattggatt
     1081 actgtatcac aaatgcttat gatgacaagt ttgatacagc tgccattgca ccagtagtta
     1141 aacttaagaa ccactacaac cttgaacttt tccatggttc tactatcgct ttcaaagaca
     1201 tggccctttc aatcttgcct tacttgctaa caacatcagc taaaaagcaa ggtgttgata
     1261 ataagattgt catcttgaca gcgacatcag gtgacactgg taaagctgcc atggctggtt
     1321 ttgcagatgt tcctggaact gaaatcattg tcttttatcc aaaagacggt gtttcaaaaa
     1381 tccaagaatt gcaaatgacc actcaaacag gagctaatac gcacgttatt gccattgatg
     1441 gtaactttga tgatgctcaa acagatgtga aacgtatgtt taatgatgtt gatttgcgtg
     1501 agaaattgtt ggctcatcat acgcaattct catcagctaa ctcaatgaac gttggtcgtt
     1561 tggtaccgca agtggtttac tatgtatatg cctatgcaca gttggttaag gcaggtcata
     1621 tccaaaacgg agataaggtg aacttcacag taccaacagg aaactttggt aatatcttgg
     1681 cggcttatta tgcacatcag attggtgttc cagttggcaa attaatctgt gcttctaatg
     1741 aaaataacgt ccttacagac ttcttcgcaa cgggtactta tgataagaaa cgtgacttca
     1801 aggtaacaac aagcccttct atggatatct tggtatcttc taacttggaa cgtttgattt
     1861 tccaccttct tggtaatgat gctactaaga ctaaagagct tatggatgca cttgtgacta
     1921 agggtgagta tactttggct gatgcagata aagatattct tgatttgttt gcagcaggtt
     1981 ttgcaactga ggatgaaaca gctgctgaaa tcaagcgtgt ctatgatgaa gacaagtata
     2041 tcgaagatcc tcatacagca gttgcctcag ctgtttacga agcatatgtt caaaagacag
     2101 atgaccacac accaacagtt atcgcttcaa cagctagccc atacaaattc ccacgtgtgg
     2161 cagtttcagc tgtcactggt aaagacagtg gggatgattt caaagcagta gaagatttgc
     2221 accaactttc aggtgtagct atcccagcgg ctgtagatgg acttgaacat gcagaagttc
     2281 gccataaaac agttgttgcg gcagctgata tgcaaaaagc agttgaaagc tatcttggtg
     2341 tataagaata aaaaaatagg agctgagaaa tcagccctat ttttatcaat atagaaaaga
     2401 atattatgac agaaacaaag aaaattctaa acatagcctt gcctgctatg gccgaaaacc
     2461 ttctacaaat gttgatgggg gttgtcgatt cttacctagt ggctcaggtg ggtattgtcg
     2521 ctatatcggg ggtttccgta gccaataata tcattacgat ttaccaagct atctttattg
     2581 ctctaggagc ctcaagtgcc agtgtcattg ccaggagttt aggaaaaggt gatgttaaag
     2641 cgactaaccg agacacttgg gatgctatta ttattaccct tgctcttagt ctcatccttg
     2701 gtctactttc catttttggt ggtggggcca ttcttaatct tttaggtact gagcaatctg
     2761 tgactcaggc tggtagtctc taccttgctc ttgtcggtgg aggagtggtt ttcctagcct
     2821 tgatgaccac ttttggtaac atcctacggg ccaagggacg acctcgtatt tccatggtcg
     2881 tcagtctttt gaccaatgtt cttaatgcta ttttatcttc tttagctatc tttgttggac
     2941 attgggggat tgttggggtc gctacagcta cggttttctc tcgtctggtt gggacagtga
     3001 tactctggca agcgatgaaa ctagatgtga agcagcttga aattaccaaa ccttttaata
     3061 gagagttgtt ggggattgca ctgccagcag caggtgaacg actgatgatg cgtgctggag
     3121 atgtggtcat cgtggctatt attgttacct ttggtacagc cgttgtcggt ggtaacgcca
     3181 ttggtgaaaa cctcacccag tttaactata tgcctggtat gggagtcgca acggctacgg
     3241 ttatcttggt tgccaatagt ctgggtcgag gggataagac gcagatgaag cgtattatac
     3301 gagagtctta ttggatttcc accttcttga tggttctggt ttcagggagt atcttgctct
     3361 ttggccaagg attatcaggt ctctttacag ataataaagc agctattgcg gctagtcagg
     3421 tagttattct ttattctttc cttgggaatc ctgtgacttc ggggacttta gtttacacag
     3481 cagtttggca aggtctgggt aaggctaaga tgcctttcta tgcgacaact attgggatgt
     3541 ggattattcg aattttctca ggatacttcc ttggggtgag tctgggaatg ggtcttgctg
     3601 gtgtctggat tgcaaccgtt gttgataatg tatggcgtgc gatcttcctc tacgtgatgt
     3661 accgtcgtta tctcgtaaag agaaagtttt aaggataaat actgaggaga tactcttatt
     3721 caaagggtat cttcttctta ttttttacaa gtaggctcga atatggtaaa ataagctgat
     3781 aaaaactttt tgaggtagta attatgactg taaaaatcaa tacaaaagat ggtcaaatcg
     3841 aattgtcaga tgatgtcatc gcaacagtag ttggcggttc agcaacagaa atttttggcg
     3901 ttgtcggtat ggcaagtaag agtgctatcc gagataattt tcaagcactt cttggaaaag
     3961 aaaactacgc aaaaggagtt gtcgtgaaat ctactgatgc aggtatcact gttgatgtct
     4021 acactgttat gagttacggt gttaagatta gtgaggtttc aaaaaatatt caagaacgtg
     4081 tgaaatttaa tcttgagaat caactcggta tcaaggctga aacagtaaat gtttacgttc
     4141 aaaatattaa agtcgtagga gaaaactagt gtctaaaatt acaacaagct tgcttcagga
     4201 gatggtccaa gcggcagcaa cacgtctagg taagcaagca gaatatgtga attcactcaa
     4261 tgtcttccca gtaccagatg gagatactgg aacaaacatg ggaatgacta tggataacgg
     4321 agctaaagct gtcgcagatc aatcagcttc aacagttggt gaagttggtc agattttgtc
     4381 taaaggtctt ttgatgggtg cccgtggtaa ctcaggtgtt atcacctcac aattgttccg
     4441 tggatttggt caaagtatca aggacaaaac ggaacttgac ggccaagatc tagctcatgc
     4501 cttccaagca ggggttgaag ttgcttataa agctgttatg aaacctgttg aaggaacaat
     4561 ccttacagta tcacgtggtg cagcttcagc agcgattaag aaagctgaat ctacaaatga
     4621 tgctgttgag gttatgcgtg cagctctcga tggagctaag gctgccttgg ctaagacacc
     4681 agagatgctt ccagttttga aagaagttgg tgtggtagac tcaggtggtc aaggtttggt
     4741 cttcatttat gaaggtttct tgtcagccct cacaggtgag tatatcgctt cagaggactt
     4801 ccaagcgaca cctgctacga tgacagagat gatcaatgca gaacatcata agtcagttgc
     4861 tggtcatgtt gcaacagaag acattacttt tggttactgt acggaaatca tgattggtct
     4921 caaacaaggt ccaacttatg tgaaggactt tgactatgaa gagttccaaa attacttgag
     4981 caaccttggg gattctctcc ttgttgttaa tgacgatgaa attgtcaaag ttcacgtcca
     5041 cactgaggat ccaggtcttg tcatgcaaga aggtcttaaa tatggggctc ttgtcaaagt
     5101 taaggttgac aacatgcgta accaacacga tgcacaagtt caaaaagaag aagctatcca
     5161 agctgcacct tctgctccta aagactttgc tcttattgca gttgttgctg gagatgggct
     5221 tgcagatatc ttcaaatcac aaggtgttga ctatgtgatt tcaggtggtc aaacaatgaa
     5281 cccatcaaca gaagatattg ttaaggctat tgagcaggtt aatgctaaga atgttatcat
     5341 cttgccaaac aataaaaaca tctttatggc agcacaatca gctgctgaag tagtagatgt
     5401 caatgcggca gttgttgaaa cgcgtacagt accacaaggc tttacaagct tgcttgcttt
     5461 tgatcctagc caaagtatcg aagcgaatgt tgaagctatg acagctagtc tttcagatgt
     5521 aacaagtggt agcgtgacct tggcggtacg tgacacaact attgacggac ttgagattca
     5581 tgaaaatgat atccttggta tggttgatgg taagatcctt gtgtctacac cagatatgga
     5641 tcaagccctt cttgacactt ttgacaagat gattgacgaa gacagtgaaa ttgttatgat
     5701 ttatgtcggc gaagaaggta atcaagaaca agctcaagca cttgcggaaa aattggaaga
     5761 ggctcacgaa ggtatcgaag ttgaaatctt ccaaggagac caaccagttt atccatacct
     5821 ctttagtgtt gaataatatt gaaataatca tttaggaagt cttagagctt cctttttgtt
     5881 ttgtcagttt tgatacggct gggacatctt ttcgaaatta cagaaatatt ctgaaaattc
     5941 cttgacatta ctttccaaag tggtaacata tgttgtaaga aattttatag attgaaggta
     6001 acatcatgag aagtgatatg attaaagttg gtgttgataa ggcaccagca cgcggacttt
     6061 tgtatgcgac tgggcaagtt aaatctgcca aggatatgca aaagcctttc attgctattt
     6121 gtaactctta tattgatatt gttccagggc atgttcactt gcgtgaatta gcagatattg
     6181 ccaaggaagc tatccgcgag gctggcggta ttccttttga gtttaatacc attggtgtgg
     6241 atgatgggat tgccatgggg catattggga tgcgttacag tcttccatct cgtgaattga
     6301 ttgccgattc tgcagaaaca gttattaatg cccactggtt tgacggggtt ttctatattc
     6361 ctaactgtga taagattacg ccagggatga ttttggcagc catgcgtact aatgtgccag
     6421 cagtattttg ttctggtggc cctatgaagg gtggcgttga catgactggt catcaagcga
     6481 cgctatcaag tttgtttgaa gctgtaggta cctatcaggc tggagatatg agcaaggaag
     6541 agctcgatta tttggagaaa aatgcttgtc caacttgtgg ttcatgttca ggaatgttta
     6601 ccgctaactc aatgaactgt ttgatggaag ttttgggtct tgcccttcca ggtaacggta
     6661 ctatcctagc tgtctcagat gaacgtcgtg aattggttcg tcaagcagcc acaaaattga
     6721 tggataacat caaaaataat gttcgcccac gtgatattgt gaccaaagaa gctatcgatg
     6781 atgcgtttgc tcttgatatg gctatgggtg gttcaaccaa tactgttctc catacccttg
     6841 ctattgcgcg tgaggctggt attgattatg accttaagga cattaatgaa attgccaaga
     6901 agacacctta tctctctaaa attgcccctt caagtgttta caccatgcat gatgtgcatg
     6961 aagctggtgg tgttccagcc attatcaatc agttgattaa aaagggagcc attaagggtg
     7021 atcgtattac agttactggt aaaaccttga aagaaaatgt agctggtgct gaaatcaaaa
     7081 atgaagaaat tatccatccg attgagcatc ctatttcacc agttggtggt ttgtctattc
     7141 tttacggaaa tattgctcag gatggagctg ttatcaaggt tggtggtgta gatccatctg
     7201 ttaaaacttt ccgcggtaaa gctatttgtt gtgattcaca agatcaagcc cttgagttga
     7261 ttgacaatgg aacagttaag aagggacatg tcgttgtcat tcgatacgaa ggtcctcagg
     7321 gtggtcctgg tatgccagaa atgttggcac caacttctaa gattgtcgga cgcggtcttg
     7381 gtaaggatgt ggcactgatt acggatggcc gtttctcagg agctactcgt ggtattgcta
     7441 ttggtcacgt ttctccagaa gcagcagaag gtggtaatat cgccctaatc gaagatggcg
     7501 atgaaatcgt gattgatctt ccaaaccgta ctcttgatct gcttgtcgat gatgtaaccc
     7561 ttgaagaacg tcgcaaacat ttgaaacctt tcaaatcaaa aatttcaagt ggttggttgc
     7621 gtcgctatac agcctttgct aaatcagcca atgtcggcgg aactttgatg agtgacgaag
     7681 aattcgaaga acgtaaagca gaacgtcaag cacaagaaaa aaactaagaa cattctttcc
     7741 gaagagtttg tgatattttt ctctgaaacc cttgcaaatt tggttaaaaa tgttatcata
     7801 gtatacaagg ttttgaattt ttagacaatt cgaaaaaaac aactactaaa ggaggtccat
     7861 gtgaagaaaa ttgaacttga agaagcacgc tctggtgctg atttgattct tgatacactt
     7921 cttgaacttg ggatttcaac tatctttgga tatcctggcg gagcggttct tcctttgtat
     7981 gatgctattt acaaaaatga caagattaat catatcttat ctcgtcatga gcaaggaagt
     8041 ctgcacgaag ctgaaggtta tgccaaatca actggtaaac tcggtgttgc tcttgtaacg
     8101 agtggtcctg gtgccactaa tgctattaca gggattgcag atgctatgag tgatagcgta
     8161 cctctcctag tctttactgg tcaggtagca acatcaggta ttggtaagga tgccttccaa
     8221 gaggctgaca ttgtcggaat taccatgccg attacaaaat acaattatca gattcgcgat
     8281 acagctgata ttcctcgtat tattagggaa gcggttcata ttgcaacaac tggtcgtcct
     8341 ggtccagttg ttatcgacct ccctaaagat gtcgtagcta aggaaacagc cttcatcaac
     8401 gatcctgaaa ttaatcttcc aagttaccaa ccgacgctaa gaccaaacga aatgcaaatc
     8461 aagaaaatct tgaagcagtt ggggaaagct aagaaaccgg ttattgtagc tggaggtggg
     8521 gtgtcttatt ctgaatctgc taaggagcta gttgcttttg cagaacgcta ccaaatccca
     8581 gttgtcacaa gtcttctagg acaagggaca attgctacta gtcatcccct tttcttgggt
     8641 atgggtggta tgcacggttc atatgcggct aacattgcta tgacggatgc tgactttatg
     8701 attgctattg gttgtcgttt tgatgaccgt ttgacaggta atcctaaaac atttgctaag
     8761 aatgctaagg ttgtccatat tgatgtagat ccagctgaga ttggtaaaat tattgcagtg
     8821 gaccttccag ttgttggtga tgctaagcaa gctcttgaaa tgctcttagc agaaccagtg
     8881 gttcagaata acactgaaaa atggattgaa aaagtcacaa aagacaaaga acgtgtacgt
     8941 tcttacgata agaaagaacg tatggtacag cctcaggcag ttatcgagcg tatcggtgaa
     9001 ttgactaagg gtgatgccgt tgttgttact gacgttggac aacatcaaat gtggacagct
     9061 cagtattatc cataccaaaa tgagcgtcaa ctggtgacct caggtggtct tggaacaatg
     9121 ggattcggtg tcccagcagc aattggtgct aaaattgcta atcctgataa agaagttatc
     9181 ctctttgttg gtgatggtgg tttccaaatg acgaaccaag aattggctat cttaaatatt
     9241 tacaaggtgc caatcaaggt tgttatgttg aacaaccact cacttggtat ggtacgtcaa
     9301 tggcaagagt ccttctacga agggcgtaca tcagagtctg tctttgatac cctcccagat
     9361 ttccaattga tggctcaagc ttacggcatt aagtcctaca agtttgataa tccagagaca
     9421 attgatcagg atttggaagt tatcaaggaa gacgtaccaa tgttcatcga ggtggatatc
     9481 tctcgtaaag agcatgtctt gccaatcgtt ccggctggta agagtaatca tgaaatgttg
     9541 ggggtgaagt tcaatgcgta gaatgttaac agctaaactt cagaaccgtt cgggtgtcct
     9601 taaccgcttc acaggtgttc tttcacgacg tcaagttaat attgaaagta tctctgtagg
     9661 ggcttctgag gatcctaacg tttcacgtat tacgattatt attgatgtga attctcaaaa
     9721 tgaagtggaa caaatcatca aacagcttaa tcgtcagatt gatgtgatcc gtatccgtga
     9781 tatcacggat cagccacact tggaacgtga agttatccta gttaaggtat cagcaccaac
     9841 ctctaagcgt gctgaaatct tggcgattat tcaacctttc cgtgcttcgg tggttgatgt
     9901 ggcaccaagc tctatcacta tccagatgac tggtgatgct gaaaagagcg aggcgcttct
     9961 acgagttatt cgtccttacg gaatcaagaa tatcgctcgt acgggtgcta ctggatttac
    10021 ccgtgattaa aaaatccaac ctaaatttgt taacccagcc ttaaaaaggc aataaaatat
    10081 tttttagaaa agagacatat tactatggca gttcaaatgg aatatgaaaa agacgtaaaa
    10141 gtagcagcac ttgacggtaa aaaaatcgcc gttatcggtt acggttcaca aggtcatgcg
    10201 catgcacaaa acttgcgtga ttcaggtcac gatgtgatca tcggtgttcg tccaggtaaa
    10261 tcatttgata aagctaaaga agatggtttt gatacttaca cagtagcaga agcaactaaa
    10321 ttggctgata tcattatggt tttggcacca gatgaaattc aaaaagatat ctataaagat
    10381 gaaattgagc caaacttgag tgcaggcaaa gctcttggtt ttgcacacgg atttaacatc
    10441 cacttcgaat tcatcaaggt tcctaaagat gttgatgtct ttatggttgc tcctaaagga
    10501 ccaggtcact tggtacgccg tacatataca gaaggctttg gtgttcctgc actttacgca
    10561 gtataccaag atgctacagg taatgctaaa gatatcgcta tggactgggc taaaggtatt
    10621 ggttctgcac gtgttggatt acttgtaaca acatttaaag aagaaactga agaagatttg
    10681 tttggtgaac aagcggttct tatgggtggg ttgacacacc ttattgaagc tggttttgaa
    10741 gtcttgactg aagcaggcta tgcaccacaa ttagcttact ttgaagtgct tcacgaaatg
    10801 aaattgattg ttgacttgat ctacgaaggt ggattcaaga aaatgcgtca atcatgttca
    10861 aatactgcag aatttggtga ctttgtaact ggtccacgtg tcatcggtcc agaagtcaaa
    10921 gaaaacatga aagctgccct tgctgatatc caatcaggta aatttgcacg tgaattcgtt
    10981 gaagaccatg atgctggctt cccacgtttg aaagcttacc gtaaagaagc tgaagagctt
    11041 gaaattgaaa agattggtgc tgaattgcgt aaagcaatgc cattcgttgg tcaaaacgac
    11101 gatgacgcat tcaaaatcta taactaatgt gatagtctca aaaaccagtt tagtactggt
    11161 ttttttgtgt tctgaagaga gtagttggta atcaatccta ctgctctttt ttggtcttga
    11221 atatacaata taagtgcaca ataaaaactc ataagatttt ctagtaaaat agaattgaac
    11281 gaactagtta
//
