LOCUS       c00022_gnlPro..        11487 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MONBIKKJ_22.
ACCESSION   c00022_gnlPro..
VERSION     c00022_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 09:30:38
            Original ID  :: gnl|Prokka|MONBIKKJ_22
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11487
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11487
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1057:11324]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1058..11324
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..11487
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..11487
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(453..803)
                     /locus_tag="ctg22_1"
                     /transl_table=11
                     /translation="MRLIKNTTELIGIKDQNIKISLVFETDTHIEIQAKLDYPAPSCPH
                     CHGKMIKYDFQKPSKIPLLEQAGTPTLLRLKKRRFQCKNCRRVTVAETSIVEKNCQISN
                     XVRTLDEVYSNS"
     CDS             1058..2542
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_2"
                     /sec_met_domain="PALP (E-value: 1.8e-17, bitscore: 52.8,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVYQSTRDENNKVTASQAILQGLATDGGLFTPLSTPEVTLNFD
                     QLKDASYQEVAKLVLSAFLDDFTEEELDYCITNAYDDKFDTAAIAPVVKLKNHYNLELF
                     HGSTIAFKDMALSILPYLLTTSAKKQGVDNKIVILTATSGDTGKAAMAGFADVPGTEII
                     VFYPKDGVSKIQELQMTTQTGANTHVIAIDGNFDDAQTDVKRMFNDVDLREKLLAHHTQ
                     FSSANSMNVGRLVPQVVYYVYAYAQLVKAGHIQNGDKVNFTVPTGNFGNILAAYYAHQI
                     GVPVGKLICASNENNVLTDFFATGTYDKKRDFKVTTSPSMDILVSSNLERLIFHLLGND
                     ATKTKELMDALVTKGEYTLADADKDILDLFAAGFATEDETAAEIKRVYDEDKYIEDPHT
                     AVASAVYEAYVQKTDDHTPTVIASTASPYKFPRVAVSAVTGKDSGDDFKAVEDLHQLSG
                     VAIPAAVDGLEHAEVRHKTVVAAADMQKAVESYLGV"
     CDS             2603..3889
                     /locus_tag="ctg22_3"
                     /transl_table=11
                     /translation="MTETKKILNIALPAMAENLLQMLMGVVDSYLVAQVGIVAISGVSV
                     ANNIITIYQAIFIALGASSASVIARSLGKGDVKATNRDTWDAIIITLALSLILGLLSIF
                     GGGAILNLLGTEQSVTQAGSLYLALVGGGVVFLALMTTFGNILRAKGRPRISMVVSLLT
                     NVLNAILSSLAIFVGHWGIVGVATATVFSRLVGTVILWQAMKLDVKQLEITKPFNRELL
                     GIALPAAGERLMMRAGDVVIVAIIVTFGTAVVGGNAIGENLTQFNYMPGMGVATATVIL
                     VANSLGRGDKTQMKRIIRESYWISTFLMVLVSGSILLFGQGLSGLFTDNKAAIAASQVV
                     ILYSFLGNPVTSGTLVYTAVWQGLGKAKMPFYATTIGMWIIRIFSGYFLGVSLGMGLAG
                     VWIATVVDNVWRAIFLYVMYRRYLVKRKF"
     CDS             4001..4366
                     /locus_tag="ctg22_4"
                     /transl_table=11
                     /translation="MTVKINTKDGQIELSDDVIATVVGGSATEIFGVVGMASKSAIRDN
                     FQALLGKENYAKGVVVKSTDAGITVDVYTVMSYGVKISEVSKNIQERVKFNLENQLGIK
                     AETVNVYVQNIKVVGEN"
     CDS             4366..6033
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dak2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg22_5"
                     /sec_met_domain="Dak2 (E-value: 2.2e-44, bitscore: 140.7,
                     seeds: 138, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSKITTSLLQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNMG
                     MTMDNGAKAVADQSASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKDKTELD
                     GQDLAHAFQAGVEVAYKAVMKPVEGTILTVSRGAASAAIKKAESTNDAVEVMRAALDGA
                     KAALAKTPEMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFQATPATMTEMI
                     NAEHHKSVAGHVATEDITFGYCTEIMIGLKQGPTYVKDFDYEEFQNYLSNLGDSLLVVN
                     DDEIVKVHVHTEDPGLVMQEGLKYGALVKVKVDNMRNQHDAQVQKEEAIQAAPSAPKDF
                     ALIAVVAGDGLADIFKSQGVDYVISGGQTMNPSTEDIVKAIEQVNAKNVIILPNNKNIF
                     MAAQSAAEVVDVNAAVVETRTVPQGFTSLLAFDPSQSIEANVEAMTASLSDVTSGSVTL
                     AVRDTTIDGLEIHENDILGMVDGKILVSTPDMDQALLDTFDKMIDEDSEIVMIYVGEEG
                     NQEQAQALAEKLEEAHEGIEVEIFQGDQPVYPYLFSVE"
     CDS             6203..7924
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_6"
                     /sec_met_domain="ILVD_EDD (E-value: 2.5e-225, bitscore:
                     738.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDMIKVGVDKAPARGLLYATGQVKSAKDMQKPFIAICNSYIDI
                     VPGHVHLRELADIAKEAIREAGGIPFEFNTIGVDDGIAMGHIGMRYSLPSRELIADSAE
                     TVINAHWFDGVFYIPNCDKITPGMILAAMRTNVPAVFCSGGPMKGGVDMTGHQATLSSL
                     FEAVGTYQAGDMSKEELDYLEKNACPTCGSCSGMFTANSMNCLMEVLGLALPGNGTILA
                     VSDERRELVRQAATKLMDNIKNNVRPRDIVTKEAIDDAFALDMAMGGSTNTVLHTLAIA
                     REAGIDYDLKDINEIAKKTPYLSKIAPSSVYTMHDVHEAGGVPAIINQLIKKGAIKGDR
                     ITVTGKTLKENVAGAEIKNEEIIHPIEHPISPVGGLSILYGNIAQDGAVIKVGGVDPSV
                     KTFRGKAICCDSQDQALELIDNGTVKKGHVVVIRYEGPQGGPGMPEMLAPTSKIVGRGL
                     GKDVALITDGRFSGATRGIAIGHVSPEAAEGGNIALIEDGDEIVIDLPNRTLDLLVDDV
                     TLEERRKHLKPFKSKISSGWLRRYTAFAKSANVGGTLMSDEEFEERKAERQAQEKN"
     CDS             8058..9758
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1e-48, bitscore:
                     154.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKKIELEEARSGADLILDTLLELGISTIFGYPGGAVLPLYDAIYK
                     NDKINHILSRHEQGSLHEAEGYAKSTGKLGVALVTSGPGATNAITGIADAMSDSVPLLV
                     FTGQVATSGIGKDAFQEADIVGITMPITKYNYQIRDTADIPRIIREAVHIATTGRPGPV
                     VIDLPKDVVAKETAFINDPEINLPSYQPTLRPNEMQIKKILKQLGKAKKPVIVAGGGVS
                     YSESAKELVAFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSYAANIAMTDADFMI
                     AIGCRFDDRLTGNPKTFAKNAKVVHIDVDPAEIGKIIAVDLPVVGDAKQALEMLLAEPV
                     VQNNTEKWIEKVTKDKERVRSYDKKERMVQPQAVIERIGELTKGDAVVVTDVGQHQMWT
                     AQYYPYQNERQLVTSGGLGTMGFGVPAAIGAKIANPDKEVILFVGDGGFQMTNQELAIL
                     NIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAYGIKSYKFDN
                     PETIDQDLEVIKEDVPMFIEVDISRKEHVLPIVPAGKSNHEMLGVKFNA"
     CDS             9751..10227
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_8"
                     /sec_met_domain="ALS_ss_C (E-value: 3.2e-29, bitscore:
                     90.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGASEDPNVSR
                     ITIIIDVNSQNEVEQIIKQLNRQIDVIRIRDITDQPHLEREVILVKVSAPTSKRAEILA
                     IIQPFRASVVDVAPSSITIQMTGDAEKSEALLRVIRPYGIKNIARTGATGFTRD"
     CDS             10302..11324
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg22_9"
                     /sec_met_domain="IlvN (E-value: 8.7e-81, bitscore: 258.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.6e-63, bitscore: 202.6,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGHDVI
                     IGVRPGKSFDKAKEDGFDTYTVAEATKLADIIMVLAPDEIQKDIYKDEIEPNLSAGKAL
                     GFAHGFNIHFEFIKVPKDVDVFMVAPKGPGHLVRRTYTEGFGVPALYAVYQDATGNAKD
                     IAMDWAKGIGSARVGLLVTTFKEETEEDLFGEQAVLMGGLTHLIEAGFEVLTEAGYAPQ
                     LAYFEVLHEMKLIVDLIYEGGFKKMRQSCSNTAEFGDFVTGPRVIGPEVKENMKAALAD
                     IQSGKFAREFVEDHDAGFPRLKAYRKEAEELEIEKIGAELRKAMPFVGQNDDDAFKIYN
                     "
ORIGIN
        1 ttccgattaa ttctgtggta ttcttaataa gtctcataag ttcttcctaa tgatggtttg
       61 gttgcttttc attatagttc ttatgggact ttttgtctgc actcaaaaag ctctataatc
      121 tctacagtgg ttttacccac tacagaaatt atagagcctt tttttgggcc ttgaattgtc
      181 aaattaagtg catactttcc ccatagaata cttcataagg tgttttccag ttaagacatt
      241 ttcgtggcct attattaagt ttgttctccc atagctgaat agtctgatca tcaaccaatg
      301 ttagatcact accctttgga aaatattctc taagtaatcc attcgtgttc tcattggttc
      361 ctcgttgcca tggagcatga gggtcaggaa aatagacttc aatgttcaat tgatcactca
      421 atttctgatg atacgtgaat tctttccctc tatcaggagt tactgtatac ttcgtcaagg
      481 gttctaacan ggttggagat ttgacagttt ttctcaacga ttgatgtctc agctaccgtg
      541 actctcctac aatttttaca ctggaagcgg cgtttcttca gacgtagtag tgttggagtt
      601 cccgcttgtt cgagaagagg gattttagaa ggcttttgaa agtcgtactt gatcattttt
      661 ccatggcaat gaggacatga tggtgcagga taatcgagtt ttgcttgaat ctctatatga
      721 gtgtcagttt caaaaacaag tgaaatcttg atgttttggt ctttaattcc gattaattct
      781 gtggtattct taataagtct cataagttct tcctaatgat ggtttggttg cttttcatta
      841 tagttcttat gggacttttt gtctgcattc aaaaagctct ataatctcta cagtgatttt
      901 acccactaca gaaattatag agccattttt tcatgtcttt gagaggagaa aatagggtga
      961 tatccgaatg attttttcac aagtcacaaa acgtgtagaa atattctgac aattatgtta
     1021 caatagagcc acagactatc taaaaagagg atttaccatg acacttgtat accaatcaac
     1081 acgtgacgaa aataataaag taacagctag tcaggctatt cttcaaggtt tggcaacaga
     1141 tggtggcttg ttcacaccgt tgtcaacgcc tgaggttact ttgaactttg atcaattgaa
     1201 agatgcttct taccaagaag ttgctaaatt agtcttgtca gctttcttgg atgattttac
     1261 tgaagaggaa ttggattact gtatcacaaa tgcttatgat gacaagtttg atacagctgc
     1321 cattgcacca gtagttaaac ttaagaacca ctacaacctt gaacttttcc atggttctac
     1381 tatcgctttc aaagacatgg ccctttcaat cttgccttac ttgctaacaa catcagctaa
     1441 aaagcaaggt gttgataata agattgtcat cttgacagcg acatcaggtg acactggtaa
     1501 agctgccatg gctggttttg cagatgttcc tggaactgaa atcattgtct tttatccaaa
     1561 agacggtgtt tcaaaaatcc aagaattgca aatgaccact caaacaggag ctaatacgca
     1621 cgttattgcc attgatggta actttgatga tgctcaaaca gatgtgaaac gtatgtttaa
     1681 tgatgttgat ttgcgtgaga aattgttggc tcatcatacg caattctcat cagctaactc
     1741 aatgaacgtt ggtcgtttgg taccgcaagt ggtttactat gtatatgcct atgcacagtt
     1801 ggttaaggca ggtcatatcc aaaacggaga taaggtgaac ttcacagtac caacaggaaa
     1861 ctttggtaat atcttggcgg cttattatgc acatcagatt ggtgttccag ttggcaaatt
     1921 aatctgtgct tctaatgaaa ataacgtcct tacagacttc ttcgcaacgg gtacttatga
     1981 taagaaacgt gacttcaagg taacaacaag cccttctatg gatatcttgg tatcttctaa
     2041 cttggaacgt ttgattttcc accttcttgg taatgatgct actaagacta aagagcttat
     2101 ggatgcactt gtgactaagg gtgagtatac tttggctgat gcagataaag atattcttga
     2161 tttgtttgca gcaggttttg caactgagga tgaaacagct gctgaaatca agcgtgtcta
     2221 tgatgaagac aagtatatcg aagatcctca tacagcagtt gcctcagctg tttacgaagc
     2281 atatgttcaa aagacagatg accacacacc aacagttatc gcttcaacag ctagcccata
     2341 caaattccca cgtgtggcag tttcagctgt cactggtaaa gacagtgggg atgatttcaa
     2401 agcagtagaa gatttgcacc aactttcagg tgtagctatc ccagcggctg tagatggact
     2461 tgaacatgca gaagttcgcc ataaaacagt tgttgcggca gctgatatgc aaaaagcagt
     2521 tgaaagctat cttggtgtat aagaataaaa aaataggagc tgagaaatca gccctatttt
     2581 tatcaatata gaaaagaata ttatgacaga aacaaagaaa attctaaaca tagccttgcc
     2641 tgctatggcc gaaaaccttc tacaaatgtt gatgggggtt gtcgattctt acctagtggc
     2701 tcaggtgggt attgtcgcta tatcgggggt ttccgtagcc aataatatca ttacgattta
     2761 ccaagctatc tttattgctc taggagcctc aagtgccagt gtcattgcca ggagtttagg
     2821 aaaaggtgat gttaaagcga ctaaccgaga cacttgggat gctattatta ttacccttgc
     2881 tcttagtctc atccttggtc tactttccat ttttggtggt ggggccattc ttaatctttt
     2941 aggtactgag caatctgtga ctcaggctgg tagtctctac cttgctcttg tcggtggagg
     3001 agtggttttc ctagccttga tgaccacttt tggtaacatc ctacgggcca agggacgacc
     3061 tcgtatttcc atggtcgtca gtcttttgac caatgttctt aatgctattt tatcttcttt
     3121 agctatcttt gttggacatt gggggattgt tggggtcgct acagctacgg ttttctctcg
     3181 tctggttggg acagtgatac tctggcaagc gatgaaacta gatgtgaagc agcttgaaat
     3241 taccaaacct tttaatagag agttgttggg gattgcactg ccagcagcag gtgaacgact
     3301 gatgatgcgt gctggagatg tggtcatcgt ggctattatt gttacctttg gtacagccgt
     3361 tgtcggtggt aacgccattg gtgaaaacct cacccagttt aactatatgc ctggtatggg
     3421 agtcgcaacg gctacggtta tcttggttgc caatagtctg ggtcgagggg ataagacgca
     3481 gatgaagcgt attatacgag agtcttattg gatttccacc ttcttgatgg ttctggtttc
     3541 agggagtatc ttgctctttg gccaaggatt atcaggtctc tttacagata ataaagcagc
     3601 tattgcggct agtcaggtag ttattcttta ttctttcctt gggaatcctg tgacttcggg
     3661 gactttagtt tacacagcag tttggcaagg tctgggtaag gctaagatgc ctttctatgc
     3721 gacaactatt gggatgtgga ttattcgaat tttctcagga tacttccttg gggtgagtct
     3781 gggaatgggt cttgctggtg tctggattgc aaccgttgtt gataatgtat ggcgtgcgat
     3841 cttcctctac gtgatgtacc gtcgttatct cgtaaagaga aagttttaag gataaatact
     3901 gaggagatac tcttattcaa agggtatctt cttcttattt tttacaagta ggctcgaata
     3961 tggtaaaata agctgataaa aactttttga ggtagtaatt atgactgtaa aaatcaatac
     4021 aaaagatggt caaatcgaat tgtcagatga tgtcatcgca acagtagttg gcggttcagc
     4081 aacagaaatt tttggcgttg tcggtatggc aagtaagagt gctatccgag ataattttca
     4141 agcacttctt ggaaaagaaa actacgcaaa aggagttgtc gtgaaatcta ctgatgcagg
     4201 tatcactgtt gatgtctaca ctgttatgag ttacggtgtt aagattagtg aggtttcaaa
     4261 aaatattcaa gaacgtgtga aatttaatct tgagaatcaa ctcggtatca aggctgaaac
     4321 agtaaatgtt tacgttcaaa atattaaagt cgtaggagaa aactagtgtc taaaattaca
     4381 acaagcttgc ttcaggagat ggtccaagcg gcagcaacac gtctaggtaa gcaagcagaa
     4441 tatgtgaatt cactcaatgt cttcccagta ccagatggag atactggaac aaacatggga
     4501 atgactatgg ataacggagc taaagctgtc gcagatcaat cagcttcaac agttggtgaa
     4561 gttggtcaga ttttgtctaa aggtcttttg atgggtgccc gtggtaactc aggtgttatc
     4621 acctcacaat tgttccgtgg atttggtcaa agtatcaagg acaaaacgga acttgacggc
     4681 caagatctag ctcatgcctt ccaagcaggg gttgaagttg cttataaagc tgttatgaaa
     4741 cctgttgaag gaacaatcct tacagtatca cgtggtgcag cttcagcagc gattaagaaa
     4801 gctgaatcta caaatgatgc tgttgaggtt atgcgtgcag ctctcgatgg agctaaggct
     4861 gccttggcta agacaccaga gatgcttcca gttttgaaag aagttggtgt ggtagactca
     4921 ggtggtcaag gtttggtctt catttatgaa ggtttcttgt cagccctcac aggtgagtat
     4981 atcgcttcag aggacttcca agcgacacct gctacgatga cagagatgat caatgcagaa
     5041 catcataagt cagttgctgg tcatgttgca acagaagaca ttacttttgg ttactgtacg
     5101 gaaatcatga ttggtctcaa acaaggtcca acttatgtga aggactttga ctatgaagag
     5161 ttccaaaatt acttgagcaa ccttggggat tctctccttg ttgttaatga cgatgaaatt
     5221 gtcaaagttc acgtccacac tgaggatcca ggtcttgtca tgcaagaagg tcttaaatat
     5281 ggggctcttg tcaaagttaa ggttgacaac atgcgtaacc aacacgatgc acaagttcaa
     5341 aaagaagaag ctatccaagc tgcaccttct gctcctaaag actttgctct tattgcagtt
     5401 gttgctggag atgggcttgc agatatcttc aaatcacaag gtgttgacta tgtgatttca
     5461 ggtggtcaaa caatgaaccc atcaacagaa gatattgtta aggctattga gcaggttaat
     5521 gctaagaatg ttatcatctt gccaaacaat aaaaacatct ttatggcagc acaatcagct
     5581 gctgaagtag tagatgtcaa tgcggcagtt gttgaaacgc gtacagtacc acaaggcttt
     5641 acaagcttgc ttgcttttga tcctagccaa agtatcgaag cgaatgttga agctatgaca
     5701 gctagtcttt cagatgtaac aagtggtagc gtgaccttgg cggtacgtga cacaactatt
     5761 gacggacttg agattcatga aaatgatatc cttggtatgg ttgatggtaa gatccttgtg
     5821 tctacaccag atatggatca agcccttctt gacacttttg acaagatgat tgacgaagac
     5881 agtgaaattg ttatgattta tgtcggcgaa gaaggtaatc aagaacaagc tcaagcactt
     5941 gcggaaaaat tggaagaggc tcacgaaggt atcgaagttg aaatcttcca aggagaccaa
     6001 ccagtttatc catacctctt tagtgttgaa taatattgaa ataatcattt aggaagtctt
     6061 agagcttcct ttttgttttg tcagttttga tacggctggg acatcttttc gaaattacag
     6121 aaatattctg aaaattcctt gacattactt tccaaagtgg taacatatgt tgtaagaaat
     6181 tttatagatt gaaggtaaca tcatgagaag tgatatgatt aaagttggtg ttgataaggc
     6241 accagcacgc ggacttttgt atgcgactgg gcaagttaaa tctgccaagg atatgcaaaa
     6301 gcctttcatt gctatttgta actcttatat tgatattgtt ccagggcatg ttcacttgcg
     6361 tgaattagca gatattgcca aggaagctat ccgcgaggct ggcggtattc cttttgagtt
     6421 taataccatt ggtgtggatg atgggattgc catggggcat attgggatgc gttacagtct
     6481 tccatctcgt gaattgattg ccgattctgc agaaacagtt attaatgccc actggtttga
     6541 cggggttttc tatattccta actgtgataa gattacgcca gggatgattt tggcagccat
     6601 gcgtactaat gtgccagcag tattttgttc tggtggccct atgaagggtg gcgttgacat
     6661 gactggtcat caagcgacgc tatcaagttt gtttgaagct gtaggtacct atcaggctgg
     6721 agatatgagc aaggaagagc tcgattattt ggagaaaaat gcttgtccaa cttgtggttc
     6781 atgttcagga atgtttaccg ctaactcaat gaactgtttg atggaagttt tgggtcttgc
     6841 ccttccaggt aacggtacta tcctagctgt ctcagatgaa cgtcgtgaat tggttcgtca
     6901 agcagccaca aaattgatgg ataacatcaa aaataatgtt cgcccacgtg atattgtgac
     6961 caaagaagct atcgatgatg cgtttgctct tgatatggct atgggtggtt caaccaatac
     7021 tgttctccat acccttgcta ttgcgcgtga ggctggtatt gattatgacc ttaaggacat
     7081 taatgaaatt gccaagaaga caccttatct ctctaaaatt gccccttcaa gtgtttacac
     7141 catgcatgat gtgcatgaag ctggtggtgt tccagccatt atcaatcagt tgattaaaaa
     7201 gggagccatt aagggtgatc gtattacagt tactggtaaa accttgaaag aaaatgtagc
     7261 tggtgctgaa atcaaaaatg aagaaattat ccatccgatt gagcatccta tttcaccagt
     7321 tggtggtttg tctattcttt acggaaatat tgctcaggat ggagctgtta tcaaggttgg
     7381 tggtgtagat ccatctgtta aaactttccg cggtaaagct atttgttgtg attcacaaga
     7441 tcaagccctt gagttgattg acaatggaac agttaagaag ggacatgtcg ttgtcattcg
     7501 atacgaaggt cctcagggtg gtcctggtat gccagaaatg ttggcaccaa cttctaagat
     7561 tgtcggacgc ggtcttggta aggatgtggc actgattacg gatggccgtt tctcaggagc
     7621 tactcgtggt attgctattg gtcacgtttc tccagaagca gcagaaggtg gtaatatcgc
     7681 cctaatcgaa gatggcgatg aaatcgtgat tgatcttcca aaccgtactc ttgatctgct
     7741 tgtcgatgat gtaacccttg aagaacgtcg caaacatttg aaacctttca aatcaaaaat
     7801 ttcaagtggt tggttgcgtc gctatacagc ctttgctaaa tcagccaatg tcggcggaac
     7861 tttgatgagt gacgaagaat tcgaagaacg taaagcagaa cgtcaagcac aagaaaaaaa
     7921 ctaagaacat tctttccgaa gagtttgtga tatttttctc tgaaaccctt gcaaatttgg
     7981 ttaaaaatgt tatcatagta tacaaggttt tgaattttta gacaattcga aaaaaacaac
     8041 tactaaagga ggtccatgtg aagaaaattg aacttgaaga agcacgctct ggtgctgatt
     8101 tgattcttga tacacttctt gaacttggga tttcaactat ctttggatat cctggcggag
     8161 cggttcttcc tttgtatgat gctatttaca aaaatgacaa gattaatcat atcttatctc
     8221 gtcatgagca aggaagtctg cacgaagctg aaggttatgc caaatcaact ggtaaactcg
     8281 gtgttgctct tgtaacgagt ggtcctggtg ccactaatgc tattacaggg attgcagatg
     8341 ctatgagtga tagcgtacct ctcctagtct ttactggtca ggtagcaaca tcaggtattg
     8401 gtaaggatgc cttccaagag gctgacattg tcggaattac catgccgatt acaaaataca
     8461 attatcagat tcgcgataca gctgatattc ctcgtattat tagggaagcg gttcatattg
     8521 caacaactgg tcgtcctggt ccagttgtta tcgacctccc taaagatgtc gtagctaagg
     8581 aaacagcctt catcaacgat cctgaaatta atcttccaag ttaccaaccg acgctaagac
     8641 caaacgaaat gcaaatcaag aaaatcttga agcagttggg gaaagctaag aaaccggtta
     8701 ttgtagctgg aggtggggtg tcttattctg aatctgctaa ggagctagtt gcttttgcag
     8761 aacgctacca aatcccagtt gtcacaagtc ttctaggaca agggacaatt gctactagtc
     8821 atcccctttt cttgggtatg ggtggtatgc acggttcata tgcggctaac attgctatga
     8881 cggatgctga ctttatgatt gctattggtt gtcgttttga tgaccgtttg acaggtaatc
     8941 ctaaaacatt tgctaagaat gctaaggttg tccatattga tgtagatcca gctgagattg
     9001 gtaaaattat tgcagtggac cttccagttg ttggtgatgc taagcaagct cttgaaatgc
     9061 tcttagcaga accagtggtt cagaataaca ctgaaaaatg gattgaaaaa gtcacaaaag
     9121 acaaagaacg tgtacgttct tacgataaga aagaacgtat ggtacagcct caggcagtta
     9181 tcgagcgtat cggtgaattg actaagggtg atgccgttgt tgttactgac gttggacaac
     9241 atcaaatgtg gacagctcag tattatccat accaaaatga gcgtcaactg gtgacctcag
     9301 gtggtcttgg aacaatggga ttcggtgtcc cagcagcaat tggtgctaaa attgctaatc
     9361 ctgataaaga agttatcctc tttgttggtg atggtggttt ccaaatgacg aaccaagaat
     9421 tggctatctt aaatatttac aaggtgccaa tcaaggttgt tatgttgaac aaccactcac
     9481 ttggtatggt acgtcaatgg caagagtcct tctacgaagg gcgtacatca gagtctgtct
     9541 ttgataccct cccagatttc caattgatgg ctcaagctta cggcattaag tcctacaagt
     9601 ttgataatcc agagacaatt gatcaggatt tggaagttat caaggaagac gtaccaatgt
     9661 tcatcgaggt ggatatctct cgtaaagagc atgtcttgcc aatcgttccg gctggtaaga
     9721 gtaatcatga aatgttgggg gtgaagttca atgcgtagaa tgttaacagc taaacttcag
     9781 aaccgttcgg gtgtccttaa ccgcttcaca ggtgttcttt cacgacgtca agttaatatt
     9841 gaaagtatct ctgtaggggc ttctgaggat cctaacgttt cacgtattac gattattatt
     9901 gatgtgaatt ctcaaaatga agtggaacaa atcatcaaac agcttaatcg tcagattgat
     9961 gtgatccgta tccgtgatat cacggatcag ccacacttgg aacgtgaagt tatcctagtt
    10021 aaggtatcag caccaacctc taagcgtgct gaaatcttgg cgattattca acctttccgt
    10081 gcttcggtgg ttgatgtggc accaagctct atcactatcc agatgactgg tgatgctgaa
    10141 aagagcgagg cgcttctacg agttattcgt ccttacggaa tcaagaatat cgctcgtacg
    10201 ggtgctactg gatttacccg tgattaaaaa atccaaccta aatttgttaa cccagcctta
    10261 aaaaggcaat aaaatatttt ttagaaaaga gacatattac tatggcagtt caaatggaat
    10321 atgaaaaaga cgtaaaagta gcagcacttg acggtaaaaa aatcgccgtt atcggttacg
    10381 gttcacaagg tcatgcgcat gcacaaaact tgcgtgattc aggtcacgat gtgatcatcg
    10441 gtgttcgtcc aggtaaatca tttgataaag ctaaagaaga tggttttgat acttacacag
    10501 tagcagaagc aactaaattg gctgatatca ttatggtttt ggcaccagat gaaattcaaa
    10561 aagatatcta taaagatgaa attgagccaa acttgagtgc aggcaaagct cttggttttg
    10621 cacacggatt taacatccac ttcgaattca tcaaggttcc taaagatgtt gatgtcttta
    10681 tggttgctcc taaaggacca ggtcacttgg tacgccgtac atatacagaa ggctttggtg
    10741 ttcctgcact ttacgcagta taccaagatg ctacaggtaa tgctaaagat atcgctatgg
    10801 actgggctaa aggtattggt tctgcacgtg ttggattact tgtaacaaca tttaaagaag
    10861 aaactgaaga agatttgttt ggtgaacaag cggttcttat gggtgggttg acacacctta
    10921 ttgaagctgg ttttgaagtc ttgactgaag caggctatgc accacaatta gcttactttg
    10981 aagtgcttca cgaaatgaaa ttgattgttg acttgatcta cgaaggtgga ttcaagaaaa
    11041 tgcgtcaatc atgttcaaat actgcagaat ttggtgactt tgtaactggt ccacgtgtca
    11101 tcggtccaga agtcaaagaa aacatgaaag ctgcccttgc tgatatccaa tcaggtaaat
    11161 ttgcacgtga attcgttgaa gaccatgatg ctggcttccc acgtttgaaa gcttaccgta
    11221 aagaagctga agagcttgaa attgaaaaga ttggtgctga attgcgtaaa gcaatgccat
    11281 tcgttggtca aaacgacgat gacgcattca aaatctataa ctaatgtgat agtctcaaaa
    11341 accagtttag tactggtttt tttgtgttct gaagagagta gttggtaatc aatcctactg
    11401 ctcttttttg gtcttgaata tacaatataa gtgcacaata aaaactcata agattttcta
    11461 gtaaaataga attgaacgaa ctagtta
//
