LOCUS       c00016_gnlPro..        10671 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ADADJIDN_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 09:42:53
            Original ID  :: gnl|Prokka|ADADJIDN_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10671
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10671
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[239:10506]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      240..10506
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10671
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10671
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             240..1724
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_1"
                     /sec_met_domain="PALP (E-value: 1.6e-17, bitscore: 52.8,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVYQSTRDENNKVTASQAILQGLATDGGLFTPLSTPEVTLNFD
                     QLKDASYQEVAKLVLSAFLDDFTEEELDYCITNAYDDKFDTAAIAPVVKLKNHYNLELF
                     HGSTIAFKDMALSILPYLLTTSAKKQGVDNKIVILTATSGDTGKAAMAGFADVPGTEII
                     VFYPKDGVSKIQELQMTTQTGANTHVIAIDGNFDDAQTDVKRMFNDVDLREKLLAHHTQ
                     FSSANSMNVGRLVPQVVYYVYAYAQLVKAGHIQNGDKVNFTVPTGNFGNILAAYYAHQI
                     GVPVGKLICASNENNVLTDFFATGTYDKKRDFKVTTSPSMDILVSSNLERLIFHLLGND
                     ATKTKELMDALVTKGEYTLADADKDILDLFAAGFATEDETAAEIKRVYDEDKYIEDPHT
                     AVASAVYEAYVQKTDDHTPTVIASTASPYKFPRVAVSAVTGKDSGDDFKAVEDLHQLSG
                     VAIPAAVDGLEHAEVRHKTVVAAADMQKAVESYLGV"
     CDS             1785..3071
                     /locus_tag="ctg16_2"
                     /transl_table=11
                     /translation="MTETKKILNIALPAMAENLLQMLMGVVDSYLVAQVGIVAISGVSV
                     ANNIITIYQAIFIALGASSASVIARSLGKGDVKATNRDTWDAIIITLALSLILGLLSIF
                     GGGAILNLLGTEQSVTQAGSLYLALVGGGVVFLALMTTFGNILRAKGRPRISMVVSLLT
                     NVLNAILSSLAIFVGHWGIVGVATATVFSRLVGTVILWQAMKLDVKQLEITKPFNRELL
                     GIALPAAGERLMMRAGDVVIVAIIVTFGTAVVGGNAIGENLTQFNYMPGMGVATATVIL
                     VANSLGRGDKTQMKRIIRESYWISTFLMVLVSGSILLFGQGLSGLFTDNKAAIAASQVV
                     ILYSFLGNPVTSGTLVYTAVWQGLGKAKMPFYATTIGMWIIRIFSGYFLGVSLGMGLAG
                     VWIATVVDNVWRAIFLYVMYRRYLVKRKF"
     CDS             3183..3548
                     /locus_tag="ctg16_3"
                     /transl_table=11
                     /translation="MTVKINTKDGQIELSDDVIATVVGGSATEIFGVVGMASKSAIRDN
                     FQALLGKENYAKGVVVKSTDAGITVDVYTVMSYGVKISEVSKNIQERVKFNLENQLGIK
                     AETVNVYVQNIKVVGEN"
     CDS             3548..5215
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dak2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_4"
                     /sec_met_domain="Dak2 (E-value: 1.9e-44, bitscore: 140.7,
                     seeds: 138, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSKITTSLLQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNMG
                     MTMDNGAKAVADQSASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKDKTELD
                     GQDLAHAFQAGVEVAYKAVMKPVEGTILTVSRGAASAAIKKAESTNDAVEVMRAALDGA
                     KAALAKTPEMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFQATPATMTEMI
                     NAEHHKSVAGHVATEDITFGYCTEIMIGLKQGPTYVKDFDYEEFQNYLSNLGDSLLVVN
                     DDEIVKVHVHTEDPGLVMQEGLKYGALVKVKVDNMRNQHDAQVQKEEAIQAAPSAPKDF
                     ALIAVVAGDGLADIFKSQGVDYVISGGQTMNPSTEDIVKAIEQVNAKNVIILPNNKNIF
                     MAAQSAAEVVDVNAAVVETRTVPQGFTSLLAFDPSQSIEANVEAMTASLSDVTSGSVTL
                     AVRDTTIDGLEIHENDILGMVDGKILVSTPDMDQALLDTFDKMIDEDSEIVMIYVGEEG
                     NQEQAQALAEKLEEAHEGIEVEIFQGDQPVYPYLFSVE"
     CDS             5385..7106
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_5"
                     /sec_met_domain="ILVD_EDD (E-value: 2.3e-225, bitscore:
                     738.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDMIKVGVDKAPARGLLYATGQVKSAKDMQKPFIAICNSYIDI
                     VPGHVHLRELADIAKEAIREAGGIPFEFNTIGVDDGIAMGHIGMRYSLPSRELIADSAE
                     TVINAHWFDGVFYIPNCDKITPGMILAAMRTNVPAVFCSGGPMKGGVDMTGHQATLSSL
                     FEAVGTYQAGDMSKEELDYLEKNACPTCGSCSGMFTANSMNCLMEVLGLALPGNGTILA
                     VSDERRELVRQAATKLMDNIKNNVRPRDIVTKEAIDDAFALDMAMGGSTNTVLHTLAIA
                     REAGIDYDLKDINEIAKKTPYLSKIAPSSVYTMHDVHEAGGVPAIINQLIKKGAIKGDR
                     ITVTGKTLKENVAGAEIKNEEIIHPIEHPISPVGGLSILYGNIAQDGAVIKVGGVDPSV
                     KTFRGKAICCDSQDQALELIDNGTVKKGHVVVIRYEGPQGGPGMPEMLAPTSKIVGRGL
                     GKDVALITDGRFSGATRGIAIGHVSPEAAEGGNIALIEDGDEIVIDLPNRTLDLLVDDV
                     TLEERRKHLKPFKSKISSGWLRRYTAFAKSANVGGTLMSDEEFEERKAERQAQEKN"
     CDS             7240..8940
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.1e-49, bitscore:
                     154.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKKIELEEARSGADLILDTLLELGISTIFGYPGGAVLPLYDAIYK
                     NDKINHILSRHEQGSLHEAEGYAKSTGKLGVALVTSGPGATNAITGIADAMSDSVPLLV
                     FTGQVATSGIGKDAFQEADIVGITMPITKYNYQIRDTADIPRIIREAVHIATTGRPGPV
                     VIDLPKDVVAKETAFINDPEINLPSYQPTLRPNEMQIKKILKQLGKAKKPVIVAGGGVS
                     YSESAKELVAFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSYAANIAMTDADFMI
                     AIGCRFDDRLTGNPKTFAKNAKVVHIDVDPAEIGKIIAVDLPVVGDAKQALEMLLAEPV
                     VQNNTEKWIEKVTKDKERVRSYDKKERMVQPQAVIERIGELTKGDAVVVTDVGQHQMWT
                     AQYYPYQNERQLVTSGGLGTMGFGVPAAIGAKIANPDKEVILFVGDGGFQMTNQELAIL
                     NIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAYGIKSYKFDN
                     PETIDQDLEVIKEDVPMFIEVDISRKEHVLPIVPAGKSNHEMLGVKFNA"
     CDS             8933..9409
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_7"
                     /sec_met_domain="ALS_ss_C (E-value: 2.8e-29, bitscore:
                     90.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGASEDPNVSR
                     ITIIIDVNSQNEVEQIIKQLNRQIDVIRIRDITDQPHLEREVILVKVSAPTSKRAEILA
                     IIQPFRASVVDVAPSSITIQMTGDAEKSEALLRVIRPYGIKNIARTGATGFTRD"
     CDS             9484..10506
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_8"
                     /sec_met_domain="IlvN (E-value: 7.7e-81, bitscore: 258.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.4e-63, bitscore: 202.6,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGHDVI
                     IGVRPGKSFDKAKEDGFDTYTVAEATKLADIIMVLAPDEIQKDIYKDEIEPNLSAGKAL
                     GFAHGFNIHFEFIKVPKDVDVFMVAPKGPGHLVRRTYTEGFGVPALYAVYQDATGNAKD
                     IAMDWAKGIGSARVGLLVTTFKEETEEDLFGEQAVLMGGLTHLIEAGFEVLTEAGYAPQ
                     LAYFEVLHEMKLIVDLIYEGGFKKMRQSCSNTAEFGDFVTGPRVIGPEVKENMKAALAD
                     IQSGKFAREFVEDHDAGFPRLKAYRKEAEELEIEKIGAELRKAMPFVGQNDDDAFKIYN
                     "
ORIGIN
        1 atggtttggt tgcttttcat tatagttctt atgggacttt ttgtctgcat tcaaaaagct
       61 ctataatctc tacagtgatt ttacccacta cagaaattat agagccattt tttcatgtct
      121 ttgagaggag aaaatagggt gatatccgaa tgattttttc acaagtcaca aaacgtgtag
      181 aaatattctg acaattatgt tacaatagag ccacagacta tctaaaaaga ggatttacca
      241 tgacacttgt ataccaatca acacgtgacg aaaataataa agtaacagct agtcaggcta
      301 ttcttcaagg tttggcaaca gatggtggct tgttcacacc gttgtcaacg cctgaggtta
      361 ctttgaactt tgatcaattg aaagatgctt cttaccaaga agttgctaaa ttagtcttgt
      421 cagctttctt ggatgatttt actgaagagg aattggatta ctgtatcaca aatgcttatg
      481 atgacaagtt tgatacagct gccattgcac cagtagttaa acttaagaac cactacaacc
      541 ttgaactttt ccatggttct actatcgctt tcaaagacat ggccctttca atcttgcctt
      601 acttgctaac aacatcagct aaaaagcaag gtgttgataa taagattgtc atcttgacag
      661 cgacatcagg tgacactggt aaagctgcca tggctggttt tgcagatgtt cctggaactg
      721 aaatcattgt cttttatcca aaagacggtg tttcaaaaat ccaagaattg caaatgacca
      781 ctcaaacagg agctaatacg cacgttattg ccattgatgg taactttgat gatgctcaaa
      841 cagatgtgaa acgtatgttt aatgatgttg atttgcgtga gaaattgttg gctcatcata
      901 cgcaattctc atcagctaac tcaatgaacg ttggtcgttt ggtaccgcaa gtggtttact
      961 atgtatatgc ctatgcacag ttggttaagg caggtcatat ccaaaacgga gataaggtga
     1021 acttcacagt accaacagga aactttggta atatcttggc ggcttattat gcacatcaga
     1081 ttggtgttcc agttggcaaa ttaatctgtg cttctaatga aaataacgtc cttacagact
     1141 tcttcgcaac gggtacttat gataagaaac gtgacttcaa ggtaacaaca agcccttcta
     1201 tggatatctt ggtatcttct aacttggaac gtttgatttt ccaccttctt ggtaatgatg
     1261 ctactaagac taaagagctt atggatgcac ttgtgactaa gggtgagtat actttggctg
     1321 atgcagataa agatattctt gatttgtttg cagcaggttt tgcaactgag gatgaaacag
     1381 ctgctgaaat caagcgtgtc tatgatgaag acaagtatat cgaagatcct catacagcag
     1441 ttgcctcagc tgtttacgaa gcatatgttc aaaagacaga tgaccacaca ccaacagtta
     1501 tcgcttcaac agctagccca tacaaattcc cacgtgtggc agtttcagct gtcactggta
     1561 aagacagtgg ggatgatttc aaagcagtag aagatttgca ccaactttca ggtgtagcta
     1621 tcccagcggc tgtagatgga cttgaacatg cagaagttcg ccataaaaca gttgttgcgg
     1681 cagctgatat gcaaaaagca gttgaaagct atcttggtgt ataagaataa aaaaatagga
     1741 gctgagaaat cagccctatt tttatcaata tagaaaagaa tattatgaca gaaacaaaga
     1801 aaattctaaa catagccttg cctgctatgg ccgaaaacct tctacaaatg ttgatggggg
     1861 ttgtcgattc ttacctagtg gctcaggtgg gtattgtcgc tatatcgggg gtttccgtag
     1921 ccaataatat cattacgatt taccaagcta tctttattgc tctaggagcc tcaagtgcca
     1981 gtgtcattgc caggagttta ggaaaaggtg atgttaaagc gactaaccga gacacttggg
     2041 atgctattat tattaccctt gctcttagtc tcatccttgg tctactttcc atttttggtg
     2101 gtggggccat tcttaatctt ttaggtactg agcaatctgt gactcaggct ggtagtctct
     2161 accttgctct tgtcggtgga ggagtggttt tcctagcctt gatgaccact tttggtaaca
     2221 tcctacgggc caagggacga cctcgtattt ccatggtcgt cagtcttttg accaatgttc
     2281 ttaatgctat tttatcttct ttagctatct ttgttggaca ttgggggatt gttggggtcg
     2341 ctacagctac ggttttctct cgtctggttg ggacagtgat actctggcaa gcgatgaaac
     2401 tagatgtgaa gcagcttgaa attaccaaac cttttaatag agagttgttg gggattgcac
     2461 tgccagcagc aggtgaacga ctgatgatgc gtgctggaga tgtggtcatc gtggctatta
     2521 ttgttacctt tggtacagcc gttgtcggtg gtaacgccat tggtgaaaac ctcacccagt
     2581 ttaactatat gcctggtatg ggagtcgcaa cggctacggt tatcttggtt gccaatagtc
     2641 tgggtcgagg ggataagacg cagatgaagc gtattatacg agagtcttat tggatttcca
     2701 ccttcttgat ggttctggtt tcagggagta tcttgctctt tggccaagga ttatcaggtc
     2761 tctttacaga taataaagca gctattgcgg ctagtcaggt agttattctt tattctttcc
     2821 ttgggaatcc tgtgacttcg gggactttag tttacacagc agtttggcaa ggtctgggta
     2881 aggctaagat gcctttctat gcgacaacta ttgggatgtg gattattcga attttctcag
     2941 gatacttcct tggggtgagt ctgggaatgg gtcttgctgg tgtctggatt gcaaccgttg
     3001 ttgataatgt atggcgtgcg atcttcctct acgtgatgta ccgtcgttat ctcgtaaaga
     3061 gaaagtttta aggataaata ctgaggagat actcttattc aaagggtatc ttcttcttat
     3121 tttttacaag taggctcgaa tatggtaaaa taagctgata aaaacttttt gaggtagtaa
     3181 ttatgactgt aaaaatcaat acaaaagatg gtcaaatcga attgtcagat gatgtcatcg
     3241 caacagtagt tggcggttca gcaacagaaa tttttggcgt tgtcggtatg gcaagtaaga
     3301 gtgctatccg agataatttt caagcacttc ttggaaaaga aaactacgca aaaggagttg
     3361 tcgtgaaatc tactgatgca ggtatcactg ttgatgtcta cactgttatg agttacggtg
     3421 ttaagattag tgaggtttca aaaaatattc aagaacgtgt gaaatttaat cttgagaatc
     3481 aactcggtat caaggctgaa acagtaaatg tttacgttca aaatattaaa gtcgtaggag
     3541 aaaactagtg tctaaaatta caacaagctt gcttcaggag atggtccaag cggcagcaac
     3601 acgtctaggt aagcaagcag aatatgtgaa ttcactcaat gtcttcccag taccagatgg
     3661 agatactgga acaaacatgg gaatgactat ggataacgga gctaaagctg tcgcagatca
     3721 atcagcttca acagttggtg aagttggtca gattttgtct aaaggtcttt tgatgggtgc
     3781 ccgtggtaac tcaggtgtta tcacctcaca attgttccgt ggatttggtc aaagtatcaa
     3841 ggacaaaacg gaacttgacg gccaagatct agctcatgcc ttccaagcag gggttgaagt
     3901 tgcttataaa gctgttatga aacctgttga aggaacaatc cttacagtat cacgtggtgc
     3961 agcttcagca gcgattaaga aagctgaatc tacaaatgat gctgttgagg ttatgcgtgc
     4021 agctctcgat ggagctaagg ctgccttggc taagacacca gagatgcttc cagttttgaa
     4081 agaagttggt gtggtagact caggtggtca aggtttggtc ttcatttatg aaggtttctt
     4141 gtcagccctc acaggtgagt atatcgcttc agaggacttc caagcgacac ctgctacgat
     4201 gacagagatg atcaatgcag aacatcataa gtcagttgct ggtcatgttg caacagaaga
     4261 cattactttt ggttactgta cggaaatcat gattggtctc aaacaaggtc caacttatgt
     4321 gaaggacttt gactatgaag agttccaaaa ttacttgagc aaccttgggg attctctcct
     4381 tgttgttaat gacgatgaaa ttgtcaaagt tcacgtccac actgaggatc caggtcttgt
     4441 catgcaagaa ggtcttaaat atggggctct tgtcaaagtt aaggttgaca acatgcgtaa
     4501 ccaacacgat gcacaagttc aaaaagaaga agctatccaa gctgcacctt ctgctcctaa
     4561 agactttgct cttattgcag ttgttgctgg agatgggctt gcagatatct tcaaatcaca
     4621 aggtgttgac tatgtgattt caggtggtca aacaatgaac ccatcaacag aagatattgt
     4681 taaggctatt gagcaggtta atgctaagaa tgttatcatc ttgccaaaca ataaaaacat
     4741 ctttatggca gcacaatcag ctgctgaagt agtagatgtc aatgcggcag ttgttgaaac
     4801 gcgtacagta ccacaaggct ttacaagctt gcttgctttt gatcctagcc aaagtatcga
     4861 agcgaatgtt gaagctatga cagctagtct ttcagatgta acaagtggta gcgtgacctt
     4921 ggcggtacgt gacacaacta ttgacggact tgagattcat gaaaatgata tccttggtat
     4981 ggttgatggt aagatccttg tgtctacacc agatatggat caagcccttc ttgacacttt
     5041 tgacaagatg attgacgaag acagtgaaat tgttatgatt tatgtcggcg aagaaggtaa
     5101 tcaagaacaa gctcaagcac ttgcggaaaa attggaagag gctcacgaag gtatcgaagt
     5161 tgaaatcttc caaggagacc aaccagttta tccatacctc tttagtgttg aataatattg
     5221 aaataatcat ttaggaagtc ttagagcttc ctttttgttt tgtcagtttt gatacggctg
     5281 ggacatcttt tcgaaattac agaaatattc tgaaaattcc ttgacattac tttccaaagt
     5341 ggtaacatat gttgtaagaa attttataga ttgaaggtaa catcatgaga agtgatatga
     5401 ttaaagttgg tgttgataag gcaccagcac gcggactttt gtatgcgact gggcaagtta
     5461 aatctgccaa ggatatgcaa aagcctttca ttgctatttg taactcttat attgatattg
     5521 ttccagggca tgttcacttg cgtgaattag cagatattgc caaggaagct atccgcgagg
     5581 ctggcggtat tccttttgag tttaatacca ttggtgtgga tgatgggatt gccatggggc
     5641 atattgggat gcgttacagt cttccatctc gtgaattgat tgccgattct gcagaaacag
     5701 ttattaatgc ccactggttt gacggggttt tctatattcc taactgtgat aagattacgc
     5761 cagggatgat tttggcagcc atgcgtacta atgtgccagc agtattttgt tctggtggcc
     5821 ctatgaaggg tggcgttgac atgactggtc atcaagcgac gctatcaagt ttgtttgaag
     5881 ctgtaggtac ctatcaggct ggagatatga gcaaggaaga gctcgattat ttggagaaaa
     5941 atgcttgtcc aacttgtggt tcatgttcag gaatgtttac cgctaactca atgaactgtt
     6001 tgatggaagt tttgggtctt gcccttccag gtaacggtac tatcctagct gtctcagatg
     6061 aacgtcgtga attggttcgt caagcagcca caaaattgat ggataacatc aaaaataatg
     6121 ttcgcccacg tgatattgtg accaaagaag ctatcgatga tgcgtttgct cttgatatgg
     6181 ctatgggtgg ttcaaccaat actgttctcc atacccttgc tattgcgcgt gaggctggta
     6241 ttgattatga ccttaaggac attaatgaaa ttgccaagaa gacaccttat ctctctaaaa
     6301 ttgccccttc aagtgtttac accatgcatg atgtgcatga agctggtggt gttccagcca
     6361 ttatcaatca gttgattaaa aagggagcca ttaagggtga tcgtattaca gttactggta
     6421 aaaccttgaa agaaaatgta gctggtgctg aaatcaaaaa tgaagaaatt atccatccga
     6481 ttgagcatcc tatttcacca gttggtggtt tgtctattct ttacggaaat attgctcagg
     6541 atggagctgt tatcaaggtt ggtggtgtag atccatctgt taaaactttc cgcggtaaag
     6601 ctatttgttg tgattcacaa gatcaagccc ttgagttgat tgacaatgga acagttaaga
     6661 agggacatgt cgttgtcatt cgatacgaag gtcctcaggg tggtcctggt atgccagaaa
     6721 tgttggcacc aacttctaag attgtcggac gcggtcttgg taaggatgtg gcactgatta
     6781 cggatggccg tttctcagga gctactcgtg gtattgctat tggtcacgtt tctccagaag
     6841 cagcagaagg tggtaatatc gccctaatcg aagatggcga tgaaatcgtg attgatcttc
     6901 caaaccgtac tcttgatctg cttgtcgatg atgtaaccct tgaagaacgt cgcaaacatt
     6961 tgaaaccttt caaatcaaaa atttcaagtg gttggttgcg tcgctataca gcctttgcta
     7021 aatcagccaa tgtcggcgga actttgatga gtgacgaaga attcgaagaa cgtaaagcag
     7081 aacgtcaagc acaagaaaaa aactaagaac attctttccg aagagtttgt gatatttttc
     7141 tctgaaaccc ttgcaaattt ggttaaaaat gttatcatag tatacaaggt tttgaatttt
     7201 tagacaattc gaaaaaaaca actactaaag gaggtccatg tgaagaaaat tgaacttgaa
     7261 gaagcacgct ctggtgctga tttgattctt gatacacttc ttgaacttgg gatttcaact
     7321 atctttggat atcctggcgg agcggttctt cctttgtatg atgctattta caaaaatgac
     7381 aagattaatc atatcttatc tcgtcatgag caaggaagtc tgcacgaagc tgaaggttat
     7441 gccaaatcaa ctggtaaact cggtgttgct cttgtaacga gtggtcctgg tgccactaat
     7501 gctattacag ggattgcaga tgctatgagt gatagcgtac ctctcctagt ctttactggt
     7561 caggtagcaa catcaggtat tggtaaggat gccttccaag aggctgacat tgtcggaatt
     7621 accatgccga ttacaaaata caattatcag attcgcgata cagctgatat tcctcgtatt
     7681 attagggaag cggttcatat tgcaacaact ggtcgtcctg gtccagttgt tatcgacctc
     7741 cctaaagatg tcgtagctaa ggaaacagcc ttcatcaacg atcctgaaat taatcttcca
     7801 agttaccaac cgacgctaag accaaacgaa atgcaaatca agaaaatctt gaagcagttg
     7861 gggaaagcta agaaaccggt tattgtagct ggaggtgggg tgtcttattc tgaatctgct
     7921 aaggagctag ttgcttttgc agaacgctac caaatcccag ttgtcacaag tcttctagga
     7981 caagggacaa ttgctactag tcatcccctt ttcttgggta tgggtggtat gcacggttca
     8041 tatgcggcta acattgctat gacggatgct gactttatga ttgctattgg ttgtcgtttt
     8101 gatgaccgtt tgacaggtaa tcctaaaaca tttgctaaga atgctaaggt tgtccatatt
     8161 gatgtagatc cagctgagat tggtaaaatt attgcagtgg accttccagt tgttggtgat
     8221 gctaagcaag ctcttgaaat gctcttagca gaaccagtgg ttcagaataa cactgaaaaa
     8281 tggattgaaa aagtcacaaa agacaaagaa cgtgtacgtt cttacgataa gaaagaacgt
     8341 atggtacagc ctcaggcagt tatcgagcgt atcggtgaat tgactaaggg tgatgccgtt
     8401 gttgttactg acgttggaca acatcaaatg tggacagctc agtattatcc ataccaaaat
     8461 gagcgtcaac tggtgacctc aggtggtctt ggaacaatgg gattcggtgt cccagcagca
     8521 attggtgcta aaattgctaa tcctgataaa gaagttatcc tctttgttgg tgatggtggt
     8581 ttccaaatga cgaaccaaga attggctatc ttaaatattt acaaggtgcc aatcaaggtt
     8641 gttatgttga acaaccactc acttggtatg gtacgtcaat ggcaagagtc cttctacgaa
     8701 gggcgtacat cagagtctgt ctttgatacc ctcccagatt tccaattgat ggctcaagct
     8761 tacggcatta agtcctacaa gtttgataat ccagagacaa ttgatcagga tttggaagtt
     8821 atcaaggaag acgtaccaat gttcatcgag gtggatatct ctcgtaaaga gcatgtcttg
     8881 ccaatcgttc cggctggtaa gagtaatcat gaaatgttgg gggtgaagtt caatgcgtag
     8941 aatgttaaca gctaaacttc agaaccgttc gggtgtcctt aaccgcttca caggtgttct
     9001 ttcacgacgt caagttaata ttgaaagtat ctctgtaggg gcttctgagg atcctaacgt
     9061 ttcacgtatt acgattatta ttgatgtgaa ttctcaaaat gaagtggaac aaatcatcaa
     9121 acagcttaat cgtcagattg atgtgatccg tatccgtgat atcacggatc agccacactt
     9181 ggaacgtgaa gttatcctag ttaaggtatc agcaccaacc tctaagcgtg ctgaaatctt
     9241 ggcgattatt caacctttcc gtgcttcggt ggttgatgtg gcaccaagct ctatcactat
     9301 ccagatgact ggtgatgctg aaaagagcga ggcgcttcta cgagttattc gtccttacgg
     9361 aatcaagaat atcgctcgta cgggtgctac tggatttacc cgtgattaaa aaatccaacc
     9421 taaatttgtt aacccagcct taaaaaggca ataaaatatt ttttagaaaa gagacatatt
     9481 actatggcag ttcaaatgga atatgaaaaa gacgtaaaag tagcagcact tgacggtaaa
     9541 aaaatcgccg ttatcggtta cggttcacaa ggtcatgcgc atgcacaaaa cttgcgtgat
     9601 tcaggtcacg atgtgatcat cggtgttcgt ccaggtaaat catttgataa agctaaagaa
     9661 gatggttttg atacttacac agtagcagaa gcaactaaat tggctgatat cattatggtt
     9721 ttggcaccag atgaaattca aaaagatatc tataaagatg aaattgagcc aaacttgagt
     9781 gcaggcaaag ctcttggttt tgcacacgga tttaacatcc acttcgaatt catcaaggtt
     9841 cctaaagatg ttgatgtctt tatggttgct cctaaaggac caggtcactt ggtacgccgt
     9901 acatatacag aaggctttgg tgttcctgca ctttacgcag tataccaaga tgctacaggt
     9961 aatgctaaag atatcgctat ggactgggct aaaggtattg gttctgcacg tgttggatta
    10021 cttgtaacaa catttaaaga agaaactgaa gaagatttgt ttggtgaaca agcggttctt
    10081 atgggtgggt tgacacacct tattgaagct ggttttgaag tcttgactga agcaggctat
    10141 gcaccacaat tagcttactt tgaagtgctt cacgaaatga aattgattgt tgacttgatc
    10201 tacgaaggtg gattcaagaa aatgcgtcaa tcatgttcaa atactgcaga atttggtgac
    10261 tttgtaactg gtccacgtgt catcggtcca gaagtcaaag aaaacatgaa agctgccctt
    10321 gctgatatcc aatcaggtaa atttgcacgt gaattcgttg aagaccatga tgctggcttc
    10381 ccacgtttga aagcttaccg taaagaagct gaagagcttg aaattgaaaa gattggtgct
    10441 gaattgcgta aagcaatgcc attcgttggt caaaacgacg atgacgcatt caaaatctat
    10501 aactaatgtg atagtctcaa aaaccagttt agtactggtt tttttgtgtt ctgaagagag
    10561 tagttggtaa tcaatcctac tgctcttttt tggtcttgaa tatacaatat aagtgcacaa
    10621 taaaaactca taagattttc tagtaaaata gaattgaacg aactagttac g
//
