LOCUS       c00015_gnlPro..        10670 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KOIPBLHL_15.
ACCESSION   c00015_gnlPro..
VERSION     c00015_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 09:32:53
            Original ID  :: gnl|Prokka|KOIPBLHL_15
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10670
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10670
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[240:10507]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      241..10507
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..10670
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10670
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             241..1725
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: PALP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_1"
                     /sec_met_domain="PALP (E-value: 1.6e-17, bitscore: 52.8,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLVYQSTRDENNKVTASQAILQGLATDGGLFTPLSTPEVTLNFD
                     QLKDASYQEVAKLVLSAFLDDFTEEELDYCITNAYDDKFDTAAIAPVVKLKNHYNLELF
                     HGSTIAFKDMALSILPYLLTTSAKKQGVDNKIVILTATSGDTGKAAMAGFADVPGTEII
                     VFYPKDGVSKIQELQMTTQTGANTHVIAIDGNFDDAQTDVKRMFNDVDLREKLLAHHTQ
                     FSSANSMNVGRLVPQVVYYVYAYAQLVKAGHIQNGDKVNFTVPTGNFGNILAAYYAHQI
                     GVPVGKLICASNENNVLTDFFATGTYDKKRDFKVTTSPSMDILVSSNLERLIFHLLGND
                     ATKTKELMDALVTKGEYTLADADKDILDLFAAGFATEDETAAEIKRVYDEDKYIEDPHT
                     AVASAVYEAYVQKTDDHTPTVIASTASPYKFPRVAVSAVTGKDSGDDFKAVEDLHQLSG
                     VAIPAAVDGLEHAEVRHKTVVAAADMQKAVESYLGV"
     CDS             1786..3072
                     /locus_tag="ctg15_2"
                     /transl_table=11
                     /translation="MTETKKILNIALPAMAENLLQMLMGVVDSYLVAQVGIVAISGVSV
                     ANNIITIYQAIFIALGASSASVIARSLGKGDVKATNRDTWDAIIITLALSLILGLLSIF
                     GGGAILNLLGTEQSVTQAGSLYLALVGGGVVFLALMTTFGNILRAKGRPRISMVVSLLT
                     NVLNAILSSLAIFVGHWGIVGVATATVFSRLVGTVILWQAMKLDVKQLEITKPFNRELL
                     GIALPAAGERLMMRAGDVVIVAIIVTFGTAVVGGNAIGENLTQFNYMPGMGVATATVIL
                     VANSLGRGDKTQMKRIIRESYWISTFLMVLVSGSILLFGQGLSGLFTDNKAAIAASQVV
                     ILYSFLGNPVTSGTLVYTAVWQGLGKAKMPFYATTIGMWIIRIFSGYFLGVSLGMGLAG
                     VWIATVVDNVWRAIFLYVMYRRYLVKRKF"
     CDS             3184..3549
                     /locus_tag="ctg15_3"
                     /transl_table=11
                     /translation="MTVKINTKDGQIELSDDVIATVVGGSATEIFGVVGMASKSAIRDN
                     FQALLGKENYAKGVVVKSTDAGITVDVYTVMSYGVKISEVSKNIQERVKFNLENQLGIK
                     AETVNVYVQNIKVVGEN"
     CDS             3549..5216
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dak2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_4"
                     /sec_met_domain="Dak2 (E-value: 1.9e-44, bitscore: 140.7,
                     seeds: 138, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VSKITTSLLQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNMG
                     MTMDNGAKAVADQSASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKDKTELD
                     GQDLAHAFQAGVEVAYKAVMKPVEGTILTVSRGAASAAIKKAESTNDAVEVMRAALDGA
                     KAALAKTPEMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFQATPATMTEMI
                     NAEHHKSVAGHVATEDITFGYCTEIMIGLKQGPTYVKDFDYEEFQNYLSNLGDSLLVVN
                     DDEIVKVHVHTEDPGLVMQEGLKYGALVKVKVDNMRNQHDAQVQKEEAIQAAPSAPKDF
                     ALIAVVAGDGLADIFKSQGVDYVISGGQTMNPSTEDIVKAIEQVNAKNVIILPNNKNIF
                     MAAQSAAEVVDVNAAVVETRTVPQGFTSLLAFDPSQSIEANVEAMTASLSDVTSGSVTL
                     AVRDTTIDGLEIHENDILGMVDGKILVSTPDMDQALLDTFDKMIDEDSEIVMIYVGEEG
                     NQEQAQALAEKLEEAHEGIEVEIFQGDQPVYPYLFSVE"
     CDS             5386..7107
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_5"
                     /sec_met_domain="ILVD_EDD (E-value: 2.3e-225, bitscore:
                     738.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSDMIKVGVDKAPARGLLYATGQVKSAKDMQKPFIAICNSYIDI
                     VPGHVHLRELADIAKEAIREAGGIPFEFNTIGVDDGIAMGHIGMRYSLPSRELIADSAE
                     TVINAHWFDGVFYIPNCDKITPGMILAAMRTNVPAVFCSGGPMKGGVDMTGHQATLSSL
                     FEAVGTYQAGDMSKEELDYLEKNACPTCGSCSGMFTANSMNCLMEVLGLALPGNGTILA
                     VSDERRELVRQAATKLMDNIKNNVRPRDIVTKEAIDDAFALDMAMGGSTNTVLHTLAIA
                     REAGIDYDLKDINEIAKKTPYLSKIAPSSVYTMHDVHEAGGVPAIINQLIKKGAIKGDR
                     ITVTGKTLKENVAGAEIKNEEIIHPIEHPISPVGGLSILYGNIAQDGAVIKVGGVDPSV
                     KTFRGKAICCDSQDQALELIDNGTVKKGHVVVIRYEGPQGGPGMPEMLAPTSKIVGRGL
                     GKDVALITDGRFSGATRGIAIGHVSPEAAEGGNIALIEDGDEIVIDLPNRTLDLLVDDV
                     TLEERRKHLKPFKSKISSGWLRRYTAFAKSANVGGTLMSDEEFEERKAERQAQEKN"
     CDS             7241..8941
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 9.1e-49, bitscore:
                     154.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKKIELEEARSGADLILDTLLELGISTIFGYPGGAVLPLYDAIYK
                     NDKINHILSRHEQGSLHEAEGYAKSTGKLGVALVTSGPGATNAITGIADAMSDSVPLLV
                     FTGQVATSGIGKDAFQEADIVGITMPITKYNYQIRDTADIPRIIREAVHIATTGRPGPV
                     VIDLPKDVVAKETAFINDPEINLPSYQPTLRPNEMQIKKILKQLGKAKKPVIVAGGGVS
                     YSESAKELVAFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSYAANIAMTDADFMI
                     AIGCRFDDRLTGNPKTFAKNAKVVHIDVDPAEIGKIIAVDLPVVGDAKQALEMLLAEPV
                     VQNNTEKWIEKVTKDKERVRSYDKKERMVQPQAVIERIGELTKGDAVVVTDVGQHQMWT
                     AQYYPYQNERQLVTSGGLGTMGFGVPAAIGAKIANPDKEVILFVGDGGFQMTNQELAIL
                     NIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAYGIKSYKFDN
                     PETIDQDLEVIKEDVPMFIEVDISRKEHVLPIVPAGKSNHEMLGVKFNA"
     CDS             8934..9410
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_7"
                     /sec_met_domain="ALS_ss_C (E-value: 2.8e-29, bitscore:
                     90.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGASEDPNVSR
                     ITIIIDVNSQNEVEQIIKQLNRQIDVIRIRDITDQPHLEREVILVKVSAPTSKRAEILA
                     IIQPFRASVVDVAPSSITIQMTGDAEKSEALLRVIRPYGIKNIARTGATGFTRD"
     CDS             9485..10507
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_8"
                     /sec_met_domain="IlvN (E-value: 7.7e-81, bitscore: 258.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.4e-63, bitscore: 202.6,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGHDVI
                     IGVRPGKSFDKAKEDGFDTYTVAEATKLADIIMVLAPDEIQKDIYKDEIEPNLSAGKAL
                     GFAHGFNIHFEFIKVPKDVDVFMVAPKGPGHLVRRTYTEGFGVPALYAVYQDATGNAKD
                     IAMDWAKGIGSARVGLLVTTFKEETEEDLFGEQAVLMGGLTHLIEAGFEVLTEAGYAPQ
                     LAYFEVLHEMKLIVDLIYEGGFKKMRQSCSNTAEFGDFVTGPRVIGPEVKENMKAALAD
                     IQSGKFAREFVEDHDAGFPRLKAYRKEAEELEIEKIGAELRKAMPFVGQNDDDAFKIYN
                     "
ORIGIN
        1 gatggtttgg ttgcttttca ttatagttct tatgggactt tttgtctgca ttcaaaaagc
       61 tctataatct ctacagtgat tttacccact acagaaatta tagagccatt ttttcatgtc
      121 tttgagagga gaaaataggg tgatatccga atgatttttt cacaagtcac aaaacgtgta
      181 gaaatattct gacaattatg ttacaataga gccacagact atctaaaaag aggatttacc
      241 atgacacttg tataccaatc aacacgtgac gaaaataata aagtaacagc tagtcaggct
      301 attcttcaag gtttggcaac agatggtggc ttgttcacac cgttgtcaac gcctgaggtt
      361 actttgaact ttgatcaatt gaaagatgct tcttaccaag aagttgctaa attagtcttg
      421 tcagctttct tggatgattt tactgaagag gaattggatt actgtatcac aaatgcttat
      481 gatgacaagt ttgatacagc tgccattgca ccagtagtta aacttaagaa ccactacaac
      541 cttgaacttt tccatggttc tactatcgct ttcaaagaca tggccctttc aatcttgcct
      601 tacttgctaa caacatcagc taaaaagcaa ggtgttgata ataagattgt catcttgaca
      661 gcgacatcag gtgacactgg taaagctgcc atggctggtt ttgcagatgt tcctggaact
      721 gaaatcattg tcttttatcc aaaagacggt gtttcaaaaa tccaagaatt gcaaatgacc
      781 actcaaacag gagctaatac gcacgttatt gccattgatg gtaactttga tgatgctcaa
      841 acagatgtga aacgtatgtt taatgatgtt gatttgcgtg agaaattgtt ggctcatcat
      901 acgcaattct catcagctaa ctcaatgaac gttggtcgtt tggtaccgca agtggtttac
      961 tatgtatatg cctatgcaca gttggttaag gcaggtcata tccaaaacgg agataaggtg
     1021 aacttcacag taccaacagg aaactttggt aatatcttgg cggcttatta tgcacatcag
     1081 attggtgttc cagttggcaa attaatctgt gcttctaatg aaaataacgt ccttacagac
     1141 ttcttcgcaa cgggtactta tgataagaaa cgtgacttca aggtaacaac aagcccttct
     1201 atggatatct tggtatcttc taacttggaa cgtttgattt tccaccttct tggtaatgat
     1261 gctactaaga ctaaagagct tatggatgca cttgtgacta agggtgagta tactttggct
     1321 gatgcagata aagatattct tgatttgttt gcagcaggtt ttgcaactga ggatgaaaca
     1381 gctgctgaaa tcaagcgtgt ctatgatgaa gacaagtata tcgaagatcc tcatacagca
     1441 gttgcctcag ctgtttacga agcatatgtt caaaagacag atgaccacac accaacagtt
     1501 atcgcttcaa cagctagccc atacaaattc ccacgtgtgg cagtttcagc tgtcactggt
     1561 aaagacagtg gggatgattt caaagcagta gaagatttgc accaactttc aggtgtagct
     1621 atcccagcgg ctgtagatgg acttgaacat gcagaagttc gccataaaac agttgttgcg
     1681 gcagctgata tgcaaaaagc agttgaaagc tatcttggtg tataagaata aaaaaatagg
     1741 agctgagaaa tcagccctat ttttatcaat atagaaaaga atattatgac agaaacaaag
     1801 aaaattctaa acatagcctt gcctgctatg gccgaaaacc ttctacaaat gttgatgggg
     1861 gttgtcgatt cttacctagt ggctcaggtg ggtattgtcg ctatatcggg ggtttccgta
     1921 gccaataata tcattacgat ttaccaagct atctttattg ctctaggagc ctcaagtgcc
     1981 agtgtcattg ccaggagttt aggaaaaggt gatgttaaag cgactaaccg agacacttgg
     2041 gatgctatta ttattaccct tgctcttagt ctcatccttg gtctactttc catttttggt
     2101 ggtggggcca ttcttaatct tttaggtact gagcaatctg tgactcaggc tggtagtctc
     2161 taccttgctc ttgtcggtgg aggagtggtt ttcctagcct tgatgaccac ttttggtaac
     2221 atcctacggg ccaagggacg acctcgtatt tccatggtcg tcagtctttt gaccaatgtt
     2281 cttaatgcta ttttatcttc tttagctatc tttgttggac attgggggat tgttggggtc
     2341 gctacagcta cggttttctc tcgtctggtt gggacagtga tactctggca agcgatgaaa
     2401 ctagatgtga agcagcttga aattaccaaa ccttttaata gagagttgtt ggggattgca
     2461 ctgccagcag caggtgaacg actgatgatg cgtgctggag atgtggtcat cgtggctatt
     2521 attgttacct ttggtacagc cgttgtcggt ggtaacgcca ttggtgaaaa cctcacccag
     2581 tttaactata tgcctggtat gggagtcgca acggctacgg ttatcttggt tgccaatagt
     2641 ctgggtcgag gggataagac gcagatgaag cgtattatac gagagtctta ttggatttcc
     2701 accttcttga tggttctggt ttcagggagt atcttgctct ttggccaagg attatcaggt
     2761 ctctttacag ataataaagc agctattgcg gctagtcagg tagttattct ttattctttc
     2821 cttgggaatc ctgtgacttc ggggacttta gtttacacag cagtttggca aggtctgggt
     2881 aaggctaaga tgcctttcta tgcgacaact attgggatgt ggattattcg aattttctca
     2941 ggatacttcc ttggggtgag tctgggaatg ggtcttgctg gtgtctggat tgcaaccgtt
     3001 gttgataatg tatggcgtgc gatcttcctc tacgtgatgt accgtcgtta tctcgtaaag
     3061 agaaagtttt aaggataaat actgaggaga tactcttatt caaagggtat cttcttctta
     3121 ttttttacaa gtaggctcga atatggtaaa ataagctgat aaaaactttt tgaggtagta
     3181 attatgactg taaaaatcaa tacaaaagat ggtcaaatcg aattgtcaga tgatgtcatc
     3241 gcaacagtag ttggcggttc agcaacagaa atttttggcg ttgtcggtat ggcaagtaag
     3301 agtgctatcc gagataattt tcaagcactt cttggaaaag aaaactacgc aaaaggagtt
     3361 gtcgtgaaat ctactgatgc aggtatcact gttgatgtct acactgttat gagttacggt
     3421 gttaagatta gtgaggtttc aaaaaatatt caagaacgtg tgaaatttaa tcttgagaat
     3481 caactcggta tcaaggctga aacagtaaat gtttacgttc aaaatattaa agtcgtagga
     3541 gaaaactagt gtctaaaatt acaacaagct tgcttcagga gatggtccaa gcggcagcaa
     3601 cacgtctagg taagcaagca gaatatgtga attcactcaa tgtcttccca gtaccagatg
     3661 gagatactgg aacaaacatg ggaatgacta tggataacgg agctaaagct gtcgcagatc
     3721 aatcagcttc aacagttggt gaagttggtc agattttgtc taaaggtctt ttgatgggtg
     3781 cccgtggtaa ctcaggtgtt atcacctcac aattgttccg tggatttggt caaagtatca
     3841 aggacaaaac ggaacttgac ggccaagatc tagctcatgc cttccaagca ggggttgaag
     3901 ttgcttataa agctgttatg aaacctgttg aaggaacaat ccttacagta tcacgtggtg
     3961 cagcttcagc agcgattaag aaagctgaat ctacaaatga tgctgttgag gttatgcgtg
     4021 cagctctcga tggagctaag gctgccttgg ctaagacacc agagatgctt ccagttttga
     4081 aagaagttgg tgtggtagac tcaggtggtc aaggtttggt cttcatttat gaaggtttct
     4141 tgtcagccct cacaggtgag tatatcgctt cagaggactt ccaagcgaca cctgctacga
     4201 tgacagagat gatcaatgca gaacatcata agtcagttgc tggtcatgtt gcaacagaag
     4261 acattacttt tggttactgt acggaaatca tgattggtct caaacaaggt ccaacttatg
     4321 tgaaggactt tgactatgaa gagttccaaa attacttgag caaccttggg gattctctcc
     4381 ttgttgttaa tgacgatgaa attgtcaaag ttcacgtcca cactgaggat ccaggtcttg
     4441 tcatgcaaga aggtcttaaa tatggggctc ttgtcaaagt taaggttgac aacatgcgta
     4501 accaacacga tgcacaagtt caaaaagaag aagctatcca agctgcacct tctgctccta
     4561 aagactttgc tcttattgca gttgttgctg gagatgggct tgcagatatc ttcaaatcac
     4621 aaggtgttga ctatgtgatt tcaggtggtc aaacaatgaa cccatcaaca gaagatattg
     4681 ttaaggctat tgagcaggtt aatgctaaga atgttatcat cttgccaaac aataaaaaca
     4741 tctttatggc agcacaatca gctgctgaag tagtagatgt caatgcggca gttgttgaaa
     4801 cgcgtacagt accacaaggc tttacaagct tgcttgcttt tgatcctagc caaagtatcg
     4861 aagcgaatgt tgaagctatg acagctagtc tttcagatgt aacaagtggt agcgtgacct
     4921 tggcggtacg tgacacaact attgacggac ttgagattca tgaaaatgat atccttggta
     4981 tggttgatgg taagatcctt gtgtctacac cagatatgga tcaagccctt cttgacactt
     5041 ttgacaagat gattgacgaa gacagtgaaa ttgttatgat ttatgtcggc gaagaaggta
     5101 atcaagaaca agctcaagca cttgcggaaa aattggaaga ggctcacgaa ggtatcgaag
     5161 ttgaaatctt ccaaggagac caaccagttt atccatacct ctttagtgtt gaataatatt
     5221 gaaataatca tttaggaagt cttagagctt cctttttgtt ttgtcagttt tgatacggct
     5281 gggacatctt ttcgaaatta cagaaatatt ctgaaaattc cttgacatta ctttccaaag
     5341 tggtaacata tgttgtaaga aattttatag attgaaggta acatcatgag aagtgatatg
     5401 attaaagttg gtgttgataa ggcaccagca cgcggacttt tgtatgcgac tgggcaagtt
     5461 aaatctgcca aggatatgca aaagcctttc attgctattt gtaactctta tattgatatt
     5521 gttccagggc atgttcactt gcgtgaatta gcagatattg ccaaggaagc tatccgcgag
     5581 gctggcggta ttccttttga gtttaatacc attggtgtgg atgatgggat tgccatgggg
     5641 catattggga tgcgttacag tcttccatct cgtgaattga ttgccgattc tgcagaaaca
     5701 gttattaatg cccactggtt tgacggggtt ttctatattc ctaactgtga taagattacg
     5761 ccagggatga ttttggcagc catgcgtact aatgtgccag cagtattttg ttctggtggc
     5821 cctatgaagg gtggcgttga catgactggt catcaagcga cgctatcaag tttgtttgaa
     5881 gctgtaggta cctatcaggc tggagatatg agcaaggaag agctcgatta tttggagaaa
     5941 aatgcttgtc caacttgtgg ttcatgttca ggaatgttta ccgctaactc aatgaactgt
     6001 ttgatggaag ttttgggtct tgcccttcca ggtaacggta ctatcctagc tgtctcagat
     6061 gaacgtcgtg aattggttcg tcaagcagcc acaaaattga tggataacat caaaaataat
     6121 gttcgcccac gtgatattgt gaccaaagaa gctatcgatg atgcgtttgc tcttgatatg
     6181 gctatgggtg gttcaaccaa tactgttctc catacccttg ctattgcgcg tgaggctggt
     6241 attgattatg accttaagga cattaatgaa attgccaaga agacacctta tctctctaaa
     6301 attgcccctt caagtgttta caccatgcat gatgtgcatg aagctggtgg tgttccagcc
     6361 attatcaatc agttgattaa aaagggagcc attaagggtg atcgtattac agttactggt
     6421 aaaaccttga aagaaaatgt agctggtgct gaaatcaaaa atgaagaaat tatccatccg
     6481 attgagcatc ctatttcacc agttggtggt ttgtctattc tttacggaaa tattgctcag
     6541 gatggagctg ttatcaaggt tggtggtgta gatccatctg ttaaaacttt ccgcggtaaa
     6601 gctatttgtt gtgattcaca agatcaagcc cttgagttga ttgacaatgg aacagttaag
     6661 aagggacatg tcgttgtcat tcgatacgaa ggtcctcagg gtggtcctgg tatgccagaa
     6721 atgttggcac caacttctaa gattgtcgga cgcggtcttg gtaaggatgt ggcactgatt
     6781 acggatggcc gtttctcagg agctactcgt ggtattgcta ttggtcacgt ttctccagaa
     6841 gcagcagaag gtggtaatat cgccctaatc gaagatggcg atgaaatcgt gattgatctt
     6901 ccaaaccgta ctcttgatct gcttgtcgat gatgtaaccc ttgaagaacg tcgcaaacat
     6961 ttgaaacctt tcaaatcaaa aatttcaagt ggttggttgc gtcgctatac agcctttgct
     7021 aaatcagcca atgtcggcgg aactttgatg agtgacgaag aattcgaaga acgtaaagca
     7081 gaacgtcaag cacaagaaaa aaactaagaa cattctttcc gaagagtttg tgatattttt
     7141 ctctgaaacc cttgcaaatt tggttaaaaa tgttatcata gtatacaagg ttttgaattt
     7201 ttagacaatt cgaaaaaaac aactactaaa ggaggtccat gtgaagaaaa ttgaacttga
     7261 agaagcacgc tctggtgctg atttgattct tgatacactt cttgaacttg ggatttcaac
     7321 tatctttgga tatcctggcg gagcggttct tcctttgtat gatgctattt acaaaaatga
     7381 caagattaat catatcttat ctcgtcatga gcaaggaagt ctgcacgaag ctgaaggtta
     7441 tgccaaatca actggtaaac tcggtgttgc tcttgtaacg agtggtcctg gtgccactaa
     7501 tgctattaca gggattgcag atgctatgag tgatagcgta cctctcctag tctttactgg
     7561 tcaggtagca acatcaggta ttggtaagga tgccttccaa gaggctgaca ttgtcggaat
     7621 taccatgccg attacaaaat acaattatca gattcgcgat acagctgata ttcctcgtat
     7681 tattagggaa gcggttcata ttgcaacaac tggtcgtcct ggtccagttg ttatcgacct
     7741 ccctaaagat gtcgtagcta aggaaacagc cttcatcaac gatcctgaaa ttaatcttcc
     7801 aagttaccaa ccgacgctaa gaccaaacga aatgcaaatc aagaaaatct tgaagcagtt
     7861 ggggaaagct aagaaaccgg ttattgtagc tggaggtggg gtgtcttatt ctgaatctgc
     7921 taaggagcta gttgcttttg cagaacgcta ccaaatccca gttgtcacaa gtcttctagg
     7981 acaagggaca attgctacta gtcatcccct tttcttgggt atgggtggta tgcacggttc
     8041 atatgcggct aacattgcta tgacggatgc tgactttatg attgctattg gttgtcgttt
     8101 tgatgaccgt ttgacaggta atcctaaaac atttgctaag aatgctaagg ttgtccatat
     8161 tgatgtagat ccagctgaga ttggtaaaat tattgcagtg gaccttccag ttgttggtga
     8221 tgctaagcaa gctcttgaaa tgctcttagc agaaccagtg gttcagaata acactgaaaa
     8281 atggattgaa aaagtcacaa aagacaaaga acgtgtacgt tcttacgata agaaagaacg
     8341 tatggtacag cctcaggcag ttatcgagcg tatcggtgaa ttgactaagg gtgatgccgt
     8401 tgttgttact gacgttggac aacatcaaat gtggacagct cagtattatc cataccaaaa
     8461 tgagcgtcaa ctggtgacct caggtggtct tggaacaatg ggattcggtg tcccagcagc
     8521 aattggtgct aaaattgcta atcctgataa agaagttatc ctctttgttg gtgatggtgg
     8581 tttccaaatg acgaaccaag aattggctat cttaaatatt tacaaggtgc caatcaaggt
     8641 tgttatgttg aacaaccact cacttggtat ggtacgtcaa tggcaagagt ccttctacga
     8701 agggcgtaca tcagagtctg tctttgatac cctcccagat ttccaattga tggctcaagc
     8761 ttacggcatt aagtcctaca agtttgataa tccagagaca attgatcagg atttggaagt
     8821 tatcaaggaa gacgtaccaa tgttcatcga ggtggatatc tctcgtaaag agcatgtctt
     8881 gccaatcgtt ccggctggta agagtaatca tgaaatgttg ggggtgaagt tcaatgcgta
     8941 gaatgttaac agctaaactt cagaaccgtt cgggtgtcct taaccgcttc acaggtgttc
     9001 tttcacgacg tcaagttaat attgaaagta tctctgtagg ggcttctgag gatcctaacg
     9061 tttcacgtat tacgattatt attgatgtga attctcaaaa tgaagtggaa caaatcatca
     9121 aacagcttaa tcgtcagatt gatgtgatcc gtatccgtga tatcacggat cagccacact
     9181 tggaacgtga agttatccta gttaaggtat cagcaccaac ctctaagcgt gctgaaatct
     9241 tggcgattat tcaacctttc cgtgcttcgg tggttgatgt ggcaccaagc tctatcacta
     9301 tccagatgac tggtgatgct gaaaagagcg aggcgcttct acgagttatt cgtccttacg
     9361 gaatcaagaa tatcgctcgt acgggtgcta ctggatttac ccgtgattaa aaaatccaac
     9421 ctaaatttgt taacccagcc ttaaaaaggc aataaaatat tttttagaaa agagacatat
     9481 tactatggca gttcaaatgg aatatgaaaa agacgtaaaa gtagcagcac ttgacggtaa
     9541 aaaaatcgcc gttatcggtt acggttcaca aggtcatgcg catgcacaaa acttgcgtga
     9601 ttcaggtcac gatgtgatca tcggtgttcg tccaggtaaa tcatttgata aagctaaaga
     9661 agatggtttt gatacttaca cagtagcaga agcaactaaa ttggctgata tcattatggt
     9721 tttggcacca gatgaaattc aaaaagatat ctataaagat gaaattgagc caaacttgag
     9781 tgcaggcaaa gctcttggtt ttgcacacgg atttaacatc cacttcgaat tcatcaaggt
     9841 tcctaaagat gttgatgtct ttatggttgc tcctaaagga ccaggtcact tggtacgccg
     9901 tacatataca gaaggctttg gtgttcctgc actttacgca gtataccaag atgctacagg
     9961 taatgctaaa gatatcgcta tggactgggc taaaggtatt ggttctgcac gtgttggatt
    10021 acttgtaaca acatttaaag aagaaactga agaagatttg tttggtgaac aagcggttct
    10081 tatgggtggg ttgacacacc ttattgaagc tggttttgaa gtcttgactg aagcaggcta
    10141 tgcaccacaa ttagcttact ttgaagtgct tcacgaaatg aaattgattg ttgacttgat
    10201 ctacgaaggt ggattcaaga aaatgcgtca atcatgttca aatactgcag aatttggtga
    10261 ctttgtaact ggtccacgtg tcatcggtcc agaagtcaaa gaaaacatga aagctgccct
    10321 tgctgatatc caatcaggta aatttgcacg tgaattcgtt gaagaccatg atgctggctt
    10381 cccacgtttg aaagcttacc gtaaagaagc tgaagagctt gaaattgaaa agattggtgc
    10441 tgaattgcgt aaagcaatgc cattcgttgg tcaaaacgac gatgacgcat tcaaaatcta
    10501 taactaatgt gatagtctca aaaaccagtt tagtactggt ttttttgtgt tctgaagaga
    10561 gtagttggta atcaatccta ctgctctttt ttggtcttga atatacaata taagtgcaca
    10621 ataaaaactc ataagatttt ctagtaaaat agaattgaac gaactagtta
//
