## Fri May 2 01:25:08 2025 ## emapper-2.1.12 ## /home/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /home/m128030022/prbbiotics_cp/prokka_results/GCA_009717425.1/GCA_009717425.1.faa --temp_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_009717425.1/2.eggNOGmapper --output_dir /home/m128030022/prbbiotics_cp/probiotics_new/databases/probiotics_DB/probiotics_db/GCA_009717425.1/2.eggNOGmapper --output eggNOG_out --override --cpu 14 -m diamond --sensmode fast ## #query seed_ortholog evalue score eggNOG_OGs max_annot_lvl COG_category Description Preferred_name GOs EC KEGG_ko KEGG_Pathway KEGG_Module KEGG_Reaction KEGG_rclass BRITE KEGG_TC CAZy BiGG_Reaction PFAMs NFINBLID_00011 1046629.Ssal_02107 0.0 2859.0 COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,4H9RF@91061|Bacilli 91061|Bacilli L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity polC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.7 ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon NFINBLID_00012 1046629.Ssal_02106 8.78e-302 822.0 COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,4H9W8@91061|Bacilli 91061|Bacilli E COG2309 Leucyl aminopeptidase (aminopeptidase T) pepS - - ko:K19689 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M29 NFINBLID_00013 904306.HMPREF9192_0535 1.4e-48 154.0 COG2261@1|root,COG2261@2|Bacteria 2|Bacteria S Transglycosylase associated protein XK27_02060 - - - - - - - - - - - Transgly_assoc NFINBLID_00014 1046629.Ssal_02104 1.28e-93 273.0 COG1846@1|root,COG1846@2|Bacteria,1VB3Q@1239|Firmicutes,4HP7J@91061|Bacilli 91061|Bacilli K Transcriptional regulator, marr family - - - - - - - - - - - - MarR NFINBLID_00015 904306.HMPREF9192_0533 1.55e-43 145.0 COG0431@1|root,COG0431@2|Bacteria,1VAI8@1239|Firmicutes 1239|Firmicutes S reductase XK27_03570 - - ko:K19784 - - - - ko00000 - - - FMN_red NFINBLID_00016 904306.HMPREF9192_0533 5.46e-57 180.0 COG0431@1|root,COG0431@2|Bacteria,1VAI8@1239|Firmicutes 1239|Firmicutes S reductase XK27_03570 - - ko:K19784 - - - - ko00000 - - - FMN_red NFINBLID_00018 435842.HMPREF0848_01881 0.0 985.0 COG3634@1|root,COG3634@2|Bacteria,1TPYN@1239|Firmicutes,4H9W1@91061|Bacilli 91061|Bacilli O alkyl hydroperoxide reductase ahpF - - ko:K03387 - - - - ko00000,ko01000 - - - Pyr_redox_2,Thioredoxin_3 NFINBLID_00019 1046629.Ssal_02101 4.96e-136 385.0 COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,4HA2M@91061|Bacilli 91061|Bacilli O alkyl hydroperoxide reductase ahpC - 1.11.1.15 ko:K03386 ko04214,map04214 - - - ko00000,ko00001,ko01000,ko04147 - - - 1-cysPrx_C,AhpC-TSA NFINBLID_00020 1046629.Ssal_02100 2.48e-176 492.0 COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,4H9N5@91061|Bacilli 91061|Bacilli J Belongs to the universal ribosomal protein uS2 family rpsB GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02967 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S2 NFINBLID_00021 1046629.Ssal_02098 1.23e-233 644.0 COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,4HBDV@91061|Bacilli 91061|Bacilli J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome tsf GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - ko:K02357 - - - - ko00000,ko03012,ko03029 - - - EF_TS NFINBLID_00022 435842.HMPREF0848_01885 3.41e-107 309.0 COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,4HPN6@91061|Bacilli 91061|Bacilli S Putative small multi-drug export protein - - - - - - - - - - - - Sm_multidrug_ex NFINBLID_00023 1046629.Ssal_02095 1.92e-97 284.0 COG4463@1|root,COG4463@2|Bacteria,1VAXT@1239|Firmicutes,4HIFT@91061|Bacilli 91061|Bacilli K Belongs to the CtsR family ctsR GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03708 - - - - ko00000,ko03000 - - - CtsR NFINBLID_00024 904306.HMPREF9192_0525 0.0 1548.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli 91061|Bacilli O Belongs to the ClpA ClpB family clpC GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,Clp_N,UVR NFINBLID_00025 1046629.Ssal_02093 7.9e-295 806.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 NFINBLID_00026 1046629.Ssal_02092 1.11e-284 780.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HBD4@91061|Bacilli 91061|Bacilli M Belongs to the peptidase S11 family dacA GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 - - - ko00000,ko00001,ko01000,ko01002,ko01011 - - - PBP5_C,Peptidase_S11 NFINBLID_00027 1046629.Ssal_02091 0.0 1388.0 COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,4H9Z3@91061|Bacilli 91061|Bacilli J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction pnp GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 M00394 R00437,R00438,R00439,R00440 RC02795 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 - - - KH_1,PNPase,RNase_PH,RNase_PH_C,S1 NFINBLID_00028 1046629.Ssal_02090 1.68e-179 500.0 2F67I@1|root,33YRI@2|Bacteria,1VY65@1239|Firmicutes,4HXHY@91061|Bacilli 91061|Bacilli S SseB protein N-terminal domain - - - - - - - - - - - - SseB NFINBLID_00029 1046629.Ssal_02089 4.02e-144 406.0 COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,4HAKS@91061|Bacilli 91061|Bacilli E serine acetyltransferase cysE - 2.3.1.30 ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 M00021 R00586 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - Hexapep NFINBLID_00030 904306.HMPREF9192_0518 0.0 887.0 COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,4HA6D@91061|Bacilli 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family cysS GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 ko:K01883 ko00970,map00970 M00359,M00360 R03650 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_2,tRNA-synt_1e,tRNA-synt_1g NFINBLID_00031 1046629.Ssal_02085 1.22e-89 263.0 COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,4HIM3@91061|Bacilli 91061|Bacilli J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc) mrnC GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - ko:K11145 - - - - ko00000,ko01000,ko03009 - - - Ribonuclease_3 NFINBLID_00033 1046629.Ssal_02082 1.68e-170 476.0 COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,4HBBI@91061|Bacilli 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family trmH GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 ko:K03218 - - - - ko00000,ko01000,ko03009 - - - SpoU_methylase,SpoU_sub_bind NFINBLID_00034 1046629.Ssal_02081 2.34e-119 341.0 COG3688@1|root,COG3688@2|Bacteria,1V9XR@1239|Firmicutes,4HFW4@91061|Bacilli 91061|Bacilli S RNA-binding protein containing a PIN domain yacP - - ko:K06962 - - - - ko00000 - - - NYN_YacP NFINBLID_00035 1046629.Ssal_02080 1.24e-196 546.0 COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,4HAYQ@91061|Bacilli 91061|Bacilli S DegV family yitS - - - - - - - - - - - DegV NFINBLID_00037 1046629.Ssal_02078 1.21e-40 134.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli 91061|Bacilli K Transcriptional - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 NFINBLID_00038 1046629.Ssal_02077 7.02e-103 297.0 COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,4HG0I@91061|Bacilli 91061|Bacilli J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly rplM GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02871 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L13 NFINBLID_00039 435842.HMPREF0848_01903 2.12e-84 249.0 COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,4HH3B@91061|Bacilli 91061|Bacilli J Belongs to the universal ribosomal protein uS9 family rpsI GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02996 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S9 NFINBLID_00040 1046629.Ssal_02074 9.57e-106 305.0 COG3682@1|root,COG3682@2|Bacteria,1VA7Q@1239|Firmicutes,4HKGF@91061|Bacilli 91061|Bacilli K Copper transport repressor, CopY TcrY family copY - - ko:K02171 ko01501,map01501 M00627 - - ko00000,ko00001,ko00002,ko01504,ko03000 - - - Penicillinase_R NFINBLID_00041 889201.HMPREF9422_1791 0.0 1194.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli 91061|Bacilli P P-type ATPase copB - 3.6.3.4 ko:K01533 - - R00086 RC00002 ko00000,ko01000 3.A.3.5 - - E1-E2_ATPase,Hydrolase NFINBLID_00043 1114965.Spaf_0449 2.7e-132 376.0 COG4300@1|root,COG4300@2|Bacteria,1V1RM@1239|Firmicutes,4HGMR@91061|Bacilli 91061|Bacilli P cadmium resistance cadD - - - - - - - - - - - Cad NFINBLID_00044 1000588.HMPREF9965_1488 3.11e-73 219.0 COG0640@1|root,COG0640@2|Bacteria,1VBPB@1239|Firmicutes,4HMSR@91061|Bacilli,2TPTX@28037|Streptococcus mitis 91061|Bacilli K Bacterial regulatory protein, arsR family cadX - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_5 NFINBLID_00046 1046629.Ssal_02065 6.1e-40 132.0 COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,4IPKE@91061|Bacilli 91061|Bacilli K Helix-turn-helix domain - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 NFINBLID_00048 435842.HMPREF0848_01916 2.13e-193 537.0 COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,4IQ4U@91061|Bacilli 91061|Bacilli S Sortase family srtB - - - - - - - - - - - Sortase NFINBLID_00049 1046629.Ssal_02062 3.65e-296 808.0 COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,4HBC3@91061|Bacilli 91061|Bacilli M Bacterial capsule synthesis protein capA - - ko:K07282 - - - - ko00000 - - - PGA_cap NFINBLID_00050 1046629.Ssal_02061 7.18e-52 164.0 COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,4HNJ4@91061|Bacilli 91061|Bacilli T UPF0237 protein XK27_08630 - - ko:K07166 - - - - ko00000 - - - ACT_6 NFINBLID_00051 904306.HMPREF9192_0489 3.65e-308 841.0 COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,4HBTU@91061|Bacilli 91061|Bacilli S UPF0210 protein XK27_08635 - - ko:K09157 - - - - ko00000 - - - DUF711 NFINBLID_00052 904306.HMPREF9192_0488 2.69e-165 462.0 COG0406@1|root,COG0406@2|Bacteria,1VDCB@1239|Firmicutes,4HJ9X@91061|Bacilli 91061|Bacilli G Phosphoglycerate mutase gpmB - - ko:K15640 - - - - ko00000 - - - His_Phos_1 NFINBLID_00053 1046629.Ssal_02058 1.13e-177 496.0 COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,4HBR1@91061|Bacilli 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase yodJ - 3.4.16.4,3.4.17.14 ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - VanY NFINBLID_00054 1046629.Ssal_02057 6.75e-132 374.0 COG1705@1|root,COG1705@2|Bacteria,1V7JY@1239|Firmicutes,4HIY4@91061|Bacilli 91061|Bacilli NU Muramidase (Flagellum-specific) acmA - 3.2.1.17,3.2.1.96 ko:K01185,ko:K01227 ko00511,map00511 - - - ko00000,ko00001,ko01000 - - - Glucosaminidase,SH3_8,YceG NFINBLID_00055 904306.HMPREF9192_0485 4.69e-237 653.0 COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,4HAX5@91061|Bacilli 91061|Bacilli K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons hrcA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K03705 - - - - ko00000,ko03000 - - - HrcA,HrcA_DNA-bdg NFINBLID_00056 1046629.Ssal_02055 2.5e-98 288.0 COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,4HIRK@91061|Bacilli 91061|Bacilli O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ grpE GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - ko:K03687 - - - - ko00000,ko03029,ko03110 - - - GrpE NFINBLID_00057 1046629.Ssal_02054 0.0 1128.0 COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,4HA9S@91061|Bacilli 91061|Bacilli O Heat shock 70 kDa protein dnaK GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:0051704,GO:0098630,GO:0098743,GO:2001065 - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 NFINBLID_00058 1046629.Ssal_02052 1e-250 690.0 COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,4H9KA@91061|Bacilli 91061|Bacilli O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins dnaJ - - ko:K03686 - - - - ko00000,ko03029,ko03110 - - - DnaJ,DnaJ_C,DnaJ_CXXCXGXG NFINBLID_00059 1046629.Ssal_02051 6.12e-178 495.0 COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,4HCFI@91061|Bacilli 91061|Bacilli J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs truA GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 ko:K06173 - - - - ko00000,ko01000,ko03016 - - - PseudoU_synth_1 NFINBLID_00060 904306.HMPREF9192_0479 1.01e-174 488.0 COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,4H9PP@91061|Bacilli 91061|Bacilli H phosphomethylpyrimidine kinase thiD - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin NFINBLID_00061 1046629.Ssal_02049 3.54e-105 304.0 COG4720@1|root,COG4720@2|Bacteria,1VBBN@1239|Firmicutes,4HNM0@91061|Bacilli 91061|Bacilli S cog cog4720 hmpT - - - - - - - - - - - ECF-ribofla_trS NFINBLID_00062 435842.HMPREF0848_01930 8.92e-87 255.0 COG1393@1|root,COG1393@2|Bacteria,1VYBB@1239|Firmicutes,4HWYC@91061|Bacilli 91061|Bacilli P Belongs to the ArsC family spxA_2 - 1.20.4.1 ko:K00537,ko:K16509 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin NFINBLID_00063 1046629.Ssal_02111 4.16e-260 714.0 COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,4HAG5@91061|Bacilli 91061|Bacilli L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage recA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K03553 ko03440,map03440 M00729 - - ko00000,ko00001,ko00002,ko03400 - - - RecA NFINBLID_00064 1046629.Ssal_02112 7.57e-287 785.0 COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,4HATN@91061|Bacilli 91061|Bacilli S Belongs to the CinA family cinA - 3.5.1.42 ko:K03742,ko:K03743 ko00760,map00760 - R02322 RC00100 ko00000,ko00001,ko01000 - - - CinA,MoCF_biosynth NFINBLID_00065 904306.HMPREF9192_0031 1.46e-132 375.0 COG2818@1|root,COG2818@2|Bacteria,1V9B8@1239|Firmicutes,4HJ4I@91061|Bacilli 91061|Bacilli L 3-methyladenine DNA glycosylase tag - 3.2.2.20 ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Adenine_glyco NFINBLID_00066 1046629.Ssal_02114 1.47e-132 376.0 COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,4HHI5@91061|Bacilli 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB ruvA - 3.6.4.12 ko:K03550 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - HHH_5,RuvA_C,RuvA_N NFINBLID_00068 1046629.Ssal_02116 0.0 1233.0 COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,4HB34@91061|Bacilli 91061|Bacilli L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex mutL GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03572 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - DNA_mis_repair,HATPase_c_3,MutL_C NFINBLID_00070 904306.HMPREF9192_0027 1.04e-89 264.0 COG3279@1|root,COG3279@2|Bacteria,1VE2H@1239|Firmicutes,4IPMG@91061|Bacilli 91061|Bacilli K LytTr DNA-binding domain - - - - - - - - - - - - LytTR NFINBLID_00071 1046629.Ssal_02119 7.24e-102 295.0 2E0UI@1|root,32WBZ@2|Bacteria,1VHBQ@1239|Firmicutes,4HRYH@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 NFINBLID_00072 904306.HMPREF9192_0025 0.0 1619.0 COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,4HA63@91061|Bacilli 91061|Bacilli L that it carries out the mismatch recognition step. This protein has a weak ATPase activity mutS GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K03555 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V NFINBLID_00073 1046629.Ssal_02121 7.11e-71 214.0 COG4550@1|root,COG4550@2|Bacteria,1V4W0@1239|Firmicutes,4HH6Y@91061|Bacilli 91061|Bacilli S Belongs to the UPF0342 family ymcA - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - Com_YlbF NFINBLID_00074 904306.HMPREF9192_0023 4.46e-89 262.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli 91061|Bacilli K Regulates arginine biosynthesis genes argR - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C NFINBLID_00075 435842.HMPREF0848_01943 0.0 1106.0 COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,4HAR3@91061|Bacilli 91061|Bacilli J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA argS GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 ko:K01887 ko00970,map00970 M00359,M00360 R03646 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d NFINBLID_00076 264199.stu0045 7.13e-313 852.0 COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,4HACW@91061|Bacilli 91061|Bacilli F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily purB GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048,M00049 R01083,R04559 RC00379,RC00444,RC00445 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS09895 ADSL_C,Lyase_1 NFINBLID_00077 365659.smi_1095 1.31e-90 298.0 COG4928@1|root,COG4928@2|Bacteria,1UQNK@1239|Firmicutes,4HNVT@91061|Bacilli 91061|Bacilli S KAP family P-loop domain - - - - - - - - - - - - KAP_NTPase NFINBLID_00080 888833.HMPREF9421_0376 1.61e-223 616.0 COG1893@1|root,COG1893@2|Bacteria,1UD8U@1239|Firmicutes 1239|Firmicutes H Ketopantoate reductase - - 1.1.1.169 ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 M00119 R02472 RC00726 ko00000,ko00001,ko00002,ko01000 - - - ApbA NFINBLID_00081 1046629.Ssal_02131 3.15e-256 703.0 COG0026@1|root,COG0026@2|Bacteria,1TQCD@1239|Firmicutes,4H9M5@91061|Bacilli 91061|Bacilli F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) purK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07404 RC01927 ko00000,ko00001,ko00002,ko01000 - - - 2-Hacid_dh_C,ATP-grasp NFINBLID_00082 1005705.HMPREF9967_0320 6.76e-106 306.0 COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,4HFR7@91061|Bacilli,43FX6@68892|Streptococcus infantis 91061|Bacilli F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) purE - 5.4.99.18 ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R07405 RC01947 ko00000,ko00001,ko00002,ko01000 - - - AIRC NFINBLID_00083 264199.stu0040 2.94e-299 816.0 COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,4HA70@91061|Bacilli 91061|Bacilli F Belongs to the GARS family purD - 6.3.4.13 ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04144 RC00090,RC00166 ko00000,ko00001,ko00002,ko01000 - - - GARS_A,GARS_C,GARS_N NFINBLID_00084 1046629.Ssal_01740 1.1e-201 558.0 COG3942@1|root,COG3942@2|Bacteria,1VUNU@1239|Firmicutes,4HVY0@91061|Bacilli 91061|Bacilli S CHAP domain - - - - - - - - - - - - CHAP,SH3_5 NFINBLID_00085 1046629.Ssal_02136 0.0 1012.0 COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,4H9YY@91061|Bacilli 91061|Bacilli F Bifunctional purine biosynthesis protein PurH purH - 2.1.2.3,3.5.4.10 ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 M00048 R01127,R04560 RC00026,RC00263,RC00456 ko00000,ko00001,ko00002,ko01000,ko04147 - - - AICARFT_IMPCHas,MGS NFINBLID_00086 264199.stu0034 1.09e-128 365.0 COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,4HGY5@91061|Bacilli 91061|Bacilli F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate purN - 2.1.2.2 ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 M00048 R04325,R04326 RC00026,RC00197,RC01128 ko00000,ko00001,ko00002,ko01000 - - - Formyl_trans_N NFINBLID_00087 435842.HMPREF0848_01955 2.63e-241 663.0 COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,4HABW@91061|Bacilli 91061|Bacilli F Phosphoribosylformylglycinamidine cyclo-ligase purM - 6.3.3.1 ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04208 RC01100 ko00000,ko00001,ko00002,ko01000 - - - AIRS,AIRS_C NFINBLID_00088 435842.HMPREF0848_01956 0.0 941.0 COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,4HAXU@91061|Bacilli 91061|Bacilli F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine purF - 2.4.2.14 ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 M00048 R01072 RC00010,RC02724,RC02752 ko00000,ko00001,ko00002,ko01000,ko01002 - - iSB619.SA_RS05225 GATase_6,GATase_7,Pribosyltran NFINBLID_00089 904306.HMPREF9192_0008 0.0 2391.0 COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,4HB3N@91061|Bacilli 91061|Bacilli F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL purL - 6.3.5.3 ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04463 RC00010,RC01160 ko00000,ko00001,ko00002,ko01000 - - - AIRS_C,GATase_5 NFINBLID_00090 1046629.Ssal_02141 3.03e-167 467.0 COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,4H9U8@91061|Bacilli 91061|Bacilli F Belongs to the SAICAR synthetase family purC - 6.3.2.6 ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 M00048 R04591 RC00064,RC00162 ko00000,ko00001,ko00002,ko01000 - - - SAICAR_synt NFINBLID_00091 435842.HMPREF0848_01959 4.06e-39 131.0 COG0236@1|root,COG0236@2|Bacteria 2|Bacteria IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP_1 - - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding NFINBLID_00092 1046629.Ssal_02143 5.9e-235 647.0 COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,4HA0R@91061|Bacilli 91061|Bacilli I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA plsX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.15 ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FA_synthesis NFINBLID_00093 1046629.Ssal_02144 1.27e-177 495.0 COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,4HAHI@91061|Bacilli 91061|Bacilli L Involved in DNA repair and RecF pathway recombination recO GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03584 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecO_C,RecO_N NFINBLID_00094 1046629.Ssal_02145 1.18e-272 747.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli 91061|Bacilli E Aminotransferase araT - - ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R04467 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 NFINBLID_00095 1046629.Ssal_02148 1.36e-223 617.0 COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,4HB61@91061|Bacilli 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N NFINBLID_00096 1046629.Ssal_02149 4.87e-142 423.0 COG3883@1|root,COG3942@1|root,COG3883@2|Bacteria,COG3942@2|Bacteria,1VCXB@1239|Firmicutes,4IS6H@91061|Bacilli 91061|Bacilli S CHAP domain pcsB - - ko:K21471 - - - - ko00000,ko01000,ko01002,ko01011 - - - CHAP NFINBLID_00097 1046629.Ssal_02150 9.73e-109 314.0 COG2891@1|root,COG2891@2|Bacteria,1VEN7@1239|Firmicutes,4HNAD@91061|Bacilli 91061|Bacilli M rod shape-determining protein MreD mreD - - ko:K03571 - - - - ko00000,ko03036 9.B.157.1 - - MreD NFINBLID_00098 435842.HMPREF0848_01966 2.9e-158 448.0 COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,4HB0K@91061|Bacilli 91061|Bacilli M Involved in formation and maintenance of cell shape mreC GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944 - ko:K03570 - - - - ko00000,ko03036 9.B.157.1 - - MreC NFINBLID_00112 1035187.HMPREF9959_0616 5.15e-50 189.0 COG1196@1|root,COG2911@1|root,COG3064@1|root,COG4932@1|root,COG1196@2|Bacteria,COG2911@2|Bacteria,COG3064@2|Bacteria,COG4932@2|Bacteria,1UN21@1239|Firmicutes,4IU59@91061|Bacilli,2TQ3M@28037|Streptococcus mitis 91061|Bacilli M Rib/alpha-like repeat - - - - - - - - - - - - Rib NFINBLID_00113 264199.stu1045 3.63e-241 667.0 COG3464@1|root,COG3464@2|Bacteria,1TQ93@1239|Firmicutes 1239|Firmicutes L Transposase - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 NFINBLID_00114 1046629.Ssal_00534 8.25e-40 138.0 COG3547@1|root,COG3547@2|Bacteria,1TQP6@1239|Firmicutes,4HDSE@91061|Bacilli 91061|Bacilli L PFAM transposase IS116 IS110 IS902 family - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 NFINBLID_00115 1046629.Ssal_00673 0.0 3188.0 COG3064@1|root,COG3583@1|root,COG3064@2|Bacteria,COG3583@2|Bacteria,1TRAR@1239|Firmicutes,4HEH7@91061|Bacilli 91061|Bacilli M signal peptide protein, YSIRK family - - - ko:K08643 - - - - ko00000,ko01000,ko01002 - - - FIVAR,G5,Gram_pos_anchor,Peptidase_M26_C,Peptidase_M26_N,Trypsin_2,YSIRK_signal NFINBLID_00116 1046629.Ssal_00675 0.0 1634.0 COG3266@1|root,COG3266@2|Bacteria 2|Bacteria GM domain, Protein - - - - - - - - - - - - Gram_pos_anchor,Laminin_G_3,YSIRK_signal NFINBLID_00117 435842.HMPREF0848_01030 7.76e-279 763.0 COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,4HAKB@91061|Bacilli 91061|Bacilli L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity sbcD - - ko:K03547 - - - - ko00000,ko03400 - - - Metallophos,SbcD_C NFINBLID_00118 1046629.Ssal_00677 0.0 1684.0 COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,4H9Q3@91061|Bacilli 91061|Bacilli L ATPase involved in DNA repair sbcC - - ko:K03546 - - - - ko00000,ko03400 - - - AAA_23,AAA_29,SbcCD_C NFINBLID_00119 264199.stu1392 0.0 1353.0 COG1216@1|root,COG1442@1|root,COG1216@2|Bacteria,COG1442@2|Bacteria,1VATJ@1239|Firmicutes,4HG1M@91061|Bacilli 91061|Bacilli M family 8 - - - - - - - - - - - - Glyco_transf_8,Glycos_transf_2 NFINBLID_00120 435842.HMPREF0848_01027 2.44e-269 740.0 COG0201@1|root,COG0201@2|Bacteria,1V59T@1239|Firmicutes,4HH1U@91061|Bacilli 91061|Bacilli U Part of the accessory SecA2 SecY2 system specifically required for export of secY2 - - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY NFINBLID_00121 904306.HMPREF9192_1013 0.0 993.0 2CI7G@1|root,2ZBRM@2|Bacteria,1V1BC@1239|Firmicutes,4HKRQ@91061|Bacilli 91061|Bacilli S Accessory Sec system protein Asp1 asp1 - - ko:K12268 - - - - ko00000,ko02044 3.A.5.10 - - Asp1 NFINBLID_00122 904306.HMPREF9192_1014 0.0 999.0 COG1073@1|root,COG1073@2|Bacteria,1TSWW@1239|Firmicutes,4HB1I@91061|Bacilli 91061|Bacilli S Accessory Sec system protein Asp2 asp2 - - ko:K12269 - - - - ko00000,ko02044 3.A.5.10 - - Asp2 NFINBLID_00123 904306.HMPREF9192_1015 4.06e-102 295.0 2AFSZ@1|root,315V3@2|Bacteria,1V6D1@1239|Firmicutes,4HS4W@91061|Bacilli 91061|Bacilli S Accessory Sec system protein Asp3 asp3 - - ko:K12270 - - - - ko00000,ko02044 3.A.5.10 - - Sec-ASP3 NFINBLID_00124 435842.HMPREF0848_01023 0.0 1510.0 COG0653@1|root,COG0653@2|Bacteria,1TRJA@1239|Firmicutes,4HCH0@91061|Bacilli 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA2 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SecA_DEAD,SecA_PP_bind,SecA_SW NFINBLID_00125 904306.HMPREF9192_1017 0.0 957.0 COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli 91061|Bacilli M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon gtf1 - 2.4.1.52 ko:K00712 - - - - ko00000,ko01000,ko01003 - GT4 - Glycos_transf_1 NFINBLID_00126 904306.HMPREF9192_1018 1.39e-310 848.0 COG0438@1|root,COG0438@2|Bacteria,1TQZR@1239|Firmicutes,4HEYJ@91061|Bacilli 91061|Bacilli M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 gtf2 - - - - - - - - - - - - NFINBLID_00127 1008453.HMPREF9957_1677 3.27e-24 92.0 2AHFC@1|root,317SM@2|Bacteria,1U4KE@1239|Firmicutes,4IEC5@91061|Bacilli,2TQ11@28037|Streptococcus mitis 91061|Bacilli S Accessory secretory protein Sec Asp4 - - - - - - - - - - - - Asp4 NFINBLID_00128 585203.SMSK564_1819 3.67e-23 90.5 2DKDD@1|root,3097M@2|Bacteria,1U4K0@1239|Firmicutes,4IEBR@91061|Bacilli,2TQ0I@28037|Streptococcus mitis 91061|Bacilli S Accessory secretory protein Sec, Asp5 - - - - - - - - - - - - Asp5 NFINBLID_00129 435842.HMPREF0848_01018 1.86e-242 665.0 COG0438@1|root,COG0438@2|Bacteria,1V6NM@1239|Firmicutes,4HISP@91061|Bacilli 91061|Bacilli M transferase activity, transferring glycosyl groups - - - - - - - - - - - - - NFINBLID_00130 435842.HMPREF0848_01017 0.0 1203.0 COG5295@1|root,COG5295@2|Bacteria 2|Bacteria UW Hep Hag repeat protein sraP - - ko:K18491,ko:K21449 ko04550,map04550 - - - ko00000,ko00001,ko02000,ko03000 1.B.40.2 - - Gram_pos_anchor,YadA_head,YadA_stalk NFINBLID_00131 435842.HMPREF0848_01017 3.64e-93 337.0 COG5295@1|root,COG5295@2|Bacteria 2|Bacteria UW Hep Hag repeat protein sraP - - ko:K18491,ko:K21449 ko04550,map04550 - - - ko00000,ko00001,ko02000,ko03000 1.B.40.2 - - Gram_pos_anchor,YadA_head,YadA_stalk NFINBLID_00132 904306.HMPREF9192_1022 0.0 1288.0 COG5295@1|root,COG5295@2|Bacteria,1VIS5@1239|Firmicutes,4HIVX@91061|Bacilli 91061|Bacilli UW domain, Protein - - - - - - - - - - - - Gram_pos_anchor NFINBLID_00133 388919.SSA_1496 5.89e-33 120.0 2BI11@1|root,32C5S@2|Bacteria,1UABR@1239|Firmicutes,4IKPW@91061|Bacilli,1WS3U@1305|Streptococcus sanguinis 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00134 1046629.Ssal_00714 0.0 2655.0 COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli 91061|Bacilli M KxYKxGKxW signal domain protein - GO:0005575,GO:0005576 2.4.1.5 ko:K00689 ko00500,ko02020,map00500,map02020 - R02120,R06066 RC00028 ko00000,ko00001,ko01000 - GH13 - Big_2,CW_binding_1,Glyco_hydro_70 NFINBLID_00135 1046629.Ssal_00717 0.0 2537.0 COG3266@1|root,COG4932@1|root,COG3266@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - 3.5.1.28 ko:K01448,ko:K13733,ko:K20276 ko01503,ko02024,ko05100,map01503,map02024,map05100 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - CHU_C,Gram_pos_anchor,MucBP,SLH NFINBLID_00136 1046629.Ssal_00718 7.63e-168 470.0 COG2220@1|root,COG2220@2|Bacteria 2|Bacteria S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - - - - - - - - - - Lactamase_B_2,Lactamase_B_3 NFINBLID_00137 435842.HMPREF0848_01001 2.57e-133 377.0 COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,4HAJ0@91061|Bacilli 91061|Bacilli GK Maltose O-acetyltransferase maa - 2.3.1.79 ko:K00661 - - - - ko00000,ko01000 - - - CM_2,Hexapep,Hexapep_2,Mac NFINBLID_00138 1046629.Ssal_00720 5.5e-83 246.0 COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes 1239|Firmicutes K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR,MarR_2 NFINBLID_00139 1046629.Ssal_00721 1.96e-295 810.0 COG0477@1|root,COG2814@2|Bacteria 2|Bacteria EGP Major facilitator Superfamily - - - ko:K18926 - M00715 - - ko00000,ko00002,ko02000 2.A.1.3.30 - - MFS_1 NFINBLID_00140 1046629.Ssal_00722 1.2e-161 454.0 28MHE@1|root,2ZAUA@2|Bacteria,1V3A5@1239|Firmicutes,4HZB2@91061|Bacilli 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi NFINBLID_00141 469609.HMPREF0847_01783 1.05e-149 427.0 COG0583@1|root,COG0583@2|Bacteria,1V5VW@1239|Firmicutes,4HHDY@91061|Bacilli 91061|Bacilli K Transcriptional regulator mleR - - - - - - - - - - - HTH_1,LysR_substrate NFINBLID_00142 467705.SGO_0371 1.45e-64 198.0 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HN0W@91061|Bacilli 91061|Bacilli K Helix-turn-helix - - - - - - - - - - - - HTH_19,HTH_3 NFINBLID_00143 888816.HMPREF9389_0191 0.0 1066.0 COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,4HBF1@91061|Bacilli,1WQU2@1305|Streptococcus sanguinis 91061|Bacilli C Malic enzyme, NAD binding domain mleS - 1.1.1.38,4.1.1.101 ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 - R00214,R11074 RC00105,RC00282 ko00000,ko00001,ko01000 - - - Malic_M,malic NFINBLID_00144 467705.SGO_0373 7.12e-206 572.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HDX5@91061|Bacilli 91061|Bacilli S auxin efflux carrier mleP - - ko:K07088 - - - - ko00000 - - - Mem_trans NFINBLID_00145 585204.SMSK597_1523 1.17e-134 406.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli,2TQ66@28037|Streptococcus mitis 91061|Bacilli S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504 2.A.1.3.37 - iYO844.BG12900 DUF2156,LPG_synthase_TM NFINBLID_00147 435842.HMPREF0848_00858 9.27e-75 223.0 COG0209@1|root,COG0209@2|Bacteria,1TT3U@1239|Firmicutes 1239|Firmicutes F Ribonucleoside-triphosphate reductase nrdD_1 - 1.1.98.6,1.17.4.1 ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024,R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - - ATP-cone,Ribonuc_red_lgC NFINBLID_00149 1046629.Ssal_00892 0.0 1523.0 COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,4HAQ9@91061|Bacilli 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily pheT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 ko:K01890 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - B3_4,B5,FDX-ACB,tRNA_bind NFINBLID_00150 904306.HMPREF9192_1478 4.88e-117 335.0 COG0454@1|root,COG0456@2|Bacteria,1VDFK@1239|Firmicutes,4HMHW@91061|Bacilli 91061|Bacilli K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases XK27_03150 - 2.3.1.57 ko:K22441 - - - - ko00000,ko01000 - - - Acetyltransf_1,Acetyltransf_10 NFINBLID_00151 1046629.Ssal_00890 1.38e-251 690.0 COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,4HAVN@91061|Bacilli 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily pheS GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 ko:K01889 ko00970,map00970 M00359,M00360 R03660 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Phe_tRNA-synt_N,tRNA-synt_2d NFINBLID_00152 1054460.SPPN_09895 4.61e-32 112.0 COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,4IPQ1@91061|Bacilli 91061|Bacilli K Helix-turn-helix domain - - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 NFINBLID_00153 1046629.Ssal_00888 5.59e-116 333.0 2EQR3@1|root,33IAY@2|Bacteria,1VK6G@1239|Firmicutes,4HRX8@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3278) - - - - - - - - - - - - DUF3278 NFINBLID_00154 264199.stu1295 0.0 1747.0 COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,4HB89@91061|Bacilli 91061|Bacilli D Required for chromosome condensation and partitioning smc - - ko:K03529 - - - - ko00000,ko03036 - - - SMC_N,SMC_hinge NFINBLID_00155 1046629.Ssal_00886 1.25e-158 445.0 COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,4HAWU@91061|Bacilli 91061|Bacilli J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism rnc GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 ko:K03685 ko03008,ko05205,map03008,map05205 - - - ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 - - - Ribonucleas_3_3,dsrm NFINBLID_00156 1046629.Ssal_00884 1.81e-222 613.0 COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,4H9K9@91061|Bacilli 91061|Bacilli E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) dapA - 4.3.3.7 ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R10147 RC03062,RC03063 ko00000,ko00001,ko00002,ko01000 - - - DHDPS NFINBLID_00157 904306.HMPREF9192_1472 2.49e-255 700.0 COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,4HA9H@91061|Bacilli 91061|Bacilli E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate asd - 1.2.1.11 ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R02291 RC00684 ko00000,ko00001,ko00002,ko01000 - - - Semialdhyde_dh,Semialdhyde_dhC NFINBLID_00158 1046629.Ssal_00882 2.07e-156 438.0 COG4912@1|root,COG4912@2|Bacteria 2|Bacteria L Dna alkylation repair alkD - - - - - - - - - - - DNA_alkylation NFINBLID_00159 1046629.Ssal_00880 0.0 1004.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol clsA_1 GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N NFINBLID_00160 904306.HMPREF9192_1469 1.36e-74 225.0 COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,4HIP1@91061|Bacilli 91061|Bacilli M acetyltransferase pat - 2.3.1.183 ko:K03823 ko00440,ko01130,map00440,map01130 - R08871,R08938 RC00004,RC00064 ko00000,ko00001,ko01000 - - - Acetyltransf_4 NFINBLID_00161 904306.HMPREF9192_1468 0.0 954.0 COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,4H9TI@91061|Bacilli 91061|Bacilli I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol cls GO:0003674,GO:0003824,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:0090407,GO:1901576 - ko:K06131 ko00564,ko01100,map00564,map01100 - R07390 RC00017 ko00000,ko00001,ko01000 - - - PLDc_2,PLDc_N NFINBLID_00162 888833.HMPREF9421_1151 0.0 968.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0008150,GO:0008324,GO:0008519,GO:0009266,GO:0009409,GO:0009628,GO:0015075,GO:0015101,GO:0015199,GO:0015651,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0022857,GO:0031460,GO:0034220,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072337,GO:0072349,GO:0072488,GO:0098655 - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT NFINBLID_00164 435842.HMPREF0848_01038 0.0 3014.0 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - - - - - - - - - - - Cna_B,FctA,Gram_pos_anchor,YSIRK_signal NFINBLID_00165 1046629.Ssal_00902 0.0 874.0 COG0446@1|root,COG0446@2|Bacteria,1TPWW@1239|Firmicutes,4H9U7@91061|Bacilli 91061|Bacilli P NADH oxidase noxE - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim NFINBLID_00166 1046629.Ssal_00901 0.0 1006.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HC58@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein yheS_1 - - - - - - - - - - - ABC_tran,ABC_tran_Xtn NFINBLID_00167 1046629.Ssal_00900 2.98e-104 303.0 COG4720@1|root,COG4720@2|Bacteria,1VC0F@1239|Firmicutes,4HMJM@91061|Bacilli 91061|Bacilli S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS NFINBLID_00168 904306.HMPREF9192_1485 1.46e-183 513.0 COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,4HHME@91061|Bacilli 91061|Bacilli H Belongs to the pyridoxine kinase family pdxK - 2.7.1.35 ko:K00868 ko00750,ko01100,map00750,map01100 - R00174,R01909,R02493 RC00002,RC00017 ko00000,ko00001,ko01000 - - - Phos_pyr_kin NFINBLID_00169 904306.HMPREF9192_1484 1.11e-107 311.0 COG4720@1|root,COG4720@2|Bacteria,1V6QK@1239|Firmicutes 1239|Firmicutes S ECF-type riboflavin transporter, S component - - - - - - - - - - - - ECF-ribofla_trS NFINBLID_00171 1046629.Ssal_00896 1.16e-301 823.0 COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,4HBNK@91061|Bacilli 91061|Bacilli K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs ycxD - - - - - - - - - - - Aminotran_1_2,GntR NFINBLID_00172 457421.CBFG_00449 8.29e-89 281.0 COG1106@1|root,COG1106@2|Bacteria,1UZQP@1239|Firmicutes,24B12@186801|Clostridia 186801|Clostridia S AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - AAA_21 NFINBLID_00173 1235792.C808_04767 1.3e-50 167.0 2DNS5@1|root,32YW9@2|Bacteria,1V58D@1239|Firmicutes,24MKB@186801|Clostridia,27MUQ@186928|unclassified Lachnospiraceae 186801|Clostridia S Psort location Cytoplasmic, score - - - - - - - - - - - - - NFINBLID_00174 435842.HMPREF0848_00767 0.0 1039.0 COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,4HA7Q@91061|Bacilli 91061|Bacilli F Catalyzes the synthesis of GMP from XMP guaA GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase,GMP_synt_C,NAD_synthase NFINBLID_00175 435842.HMPREF0848_00766 1.05e-161 453.0 COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,4HDDG@91061|Bacilli 91061|Bacilli K transcriptional yvoA_2 - - ko:K03710 - - - - ko00000,ko03000 - - - GntR,UTRA NFINBLID_00176 435842.HMPREF0848_00765 3.35e-73 219.0 COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,4HKK6@91061|Bacilli 91061|Bacilli S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein ylxM GO:0003674,GO:0008150,GO:0030234,GO:0030695,GO:0050790,GO:0060589,GO:0065007,GO:0065009,GO:0098772 - ko:K09787 - - - - ko00000 - - - UPF0122 NFINBLID_00177 1046629.Ssal_01006 0.0 956.0 COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,4H9T4@91061|Bacilli 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY ffh - 3.6.5.4 ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko01000,ko02044 3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9 - - SRP54,SRP54_N,SRP_SPB NFINBLID_00178 435842.HMPREF0848_00763 7.7e-111 320.0 2A1RE@1|root,32VI2@2|Bacteria,1VDRR@1239|Firmicutes 1239|Firmicutes - - - - - ko:K16788 - - - - ko00000,ko02000 2.A.88.5 - - ECF-ribofla_trS NFINBLID_00179 435842.HMPREF0848_00762 1.92e-118 338.0 COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,4HGYB@91061|Bacilli 91061|Bacilli S small molecule binding protein (contains 3H domain) yrxA - - ko:K07105 - - - - ko00000 - - - 3H,HTH_11 NFINBLID_00180 435842.HMPREF0848_00761 1.24e-163 457.0 COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1V758@1239|Firmicutes,4HIKZ@91061|Bacilli 91061|Bacilli K DNA-binding helix-turn-helix protein - - - - - - - - - - - - HTH_19,HTH_3,Peptidase_S24 NFINBLID_00181 1046629.Ssal_01010 6.94e-202 559.0 COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,4HA4D@91061|Bacilli 91061|Bacilli S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity rbgA GO:0003674,GO:0003824,GO:0003924,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022613,GO:0042254,GO:0044085,GO:0071840 - ko:K14540 - - - - ko00000,ko03009 - - - MMR_HSR1 NFINBLID_00182 435842.HMPREF0848_00759 7.19e-168 471.0 COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,4HB7M@91061|Bacilli 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03470 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - RNase_HII NFINBLID_00183 435842.HMPREF0848_00758 5.77e-196 546.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes 1239|Firmicutes GK ROK family - - - - - - - - - - - - ROK NFINBLID_00184 435842.HMPREF0848_00757 1.35e-201 558.0 COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,4HGWM@91061|Bacilli 91061|Bacilli LU DNA protecting protein DprA dprA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0044424,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - ko:K04096 - - - - ko00000 - - - DNA_processg_A NFINBLID_00185 435842.HMPREF0848_00756 0.0 1353.0 COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,4HA6C@91061|Bacilli 91061|Bacilli L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone topA - 5.99.1.2 ko:K03168 - - - - ko00000,ko01000,ko03032,ko03400 - - - Topoisom_bac,Toprim,zf-C4_Topoisom NFINBLID_00186 904306.HMPREF9192_1814 4.68e-195 541.0 2DC01@1|root,2ZC51@2|Bacteria,1V2FW@1239|Firmicutes,4HG69@91061|Bacilli 91061|Bacilli S TraX protein - - - - - - - - - - - - TraX NFINBLID_00187 904306.HMPREF9192_1813 1.19e-156 439.0 COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,4HDA9@91061|Bacilli 91061|Bacilli KT Transcriptional regulatory protein, C terminal spaR - - ko:K20488 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C NFINBLID_00188 435842.HMPREF0848_00753 2.55e-307 840.0 COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,4HEC4@91061|Bacilli 91061|Bacilli T ATPase histidine kinase DNA gyrase B HSP90 domain protein spaK - 2.7.13.3 ko:K20487 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA NFINBLID_00189 1046629.Ssal_01021 0.0 888.0 COG1206@1|root,COG1206@2|Bacteria,1TP67@1239|Firmicutes,4HB27@91061|Bacilli 91061|Bacilli J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs trmFO GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 ko:K04094 - - - - ko00000,ko01000,ko03016,ko03036 - - - GIDA NFINBLID_00190 1046629.Ssal_01022 2.6e-283 773.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli 91061|Bacilli E Methionine synthase XK27_05470 - - - - - - - - - - - Meth_synt_2 NFINBLID_00191 264199.stu0906 2.96e-95 278.0 COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes 1239|Firmicutes F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate ndk GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 M00049,M00050,M00052,M00053 R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895 RC00002 ko00000,ko00001,ko00002,ko01000,ko04131 - - - NDK NFINBLID_00192 904306.HMPREF9192_1808 3.93e-60 185.0 COG0607@1|root,COG0607@2|Bacteria,1U0PW@1239|Firmicutes 1239|Firmicutes P Rhodanese-like protein - - - - - - - - - - - - Rhodanese NFINBLID_00193 904306.HMPREF9192_1807 1.33e-175 490.0 COG1028@1|root,COG1028@2|Bacteria,1TRQC@1239|Firmicutes,4HD7P@91061|Bacilli 91061|Bacilli IQ Acetoin reductase butA - 1.1.1.304,1.1.1.76 ko:K03366 ko00650,map00650 - R02855,R02946,R03707,R09078,R10505 RC00205,RC00525 ko00000,ko00001,ko01000 - - - adh_short,adh_short_C2 NFINBLID_00195 1046629.Ssal_01034 0.0 1179.0 COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,4HASA@91061|Bacilli 91061|Bacilli M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner lepA - - ko:K03596 ko05134,map05134 - - - ko00000,ko00001 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2,LepA_C NFINBLID_00198 1046629.Ssal_01037 0.0 1087.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4HAV1@91061|Bacilli 91061|Bacilli EH Belongs to the TPP enzyme family alsS - 2.2.1.6 ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000 - - - TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N NFINBLID_00199 435842.HMPREF0848_00743 1.01e-167 469.0 COG3527@1|root,COG3527@2|Bacteria,1V4AH@1239|Firmicutes,4HJ98@91061|Bacilli 91061|Bacilli H Belongs to the alpha-acetolactate decarboxylase family budA - 4.1.1.5 ko:K01575 ko00650,ko00660,map00650,map00660 - R02948 RC00812 ko00000,ko00001,ko01000 - - - AAL_decarboxy NFINBLID_00200 904306.HMPREF9192_1799 1.44e-84 251.0 COG1846@1|root,COG1846@2|Bacteria,1VDJQ@1239|Firmicutes,4HN0M@91061|Bacilli 91061|Bacilli K Transcriptional regulator, MarR family - - - - - - - - - - - - MarR NFINBLID_00201 1000588.HMPREF9965_1917 4.9e-25 99.4 COG4922@1|root,COG4922@2|Bacteria,1UY32@1239|Firmicutes,4HMCD@91061|Bacilli,2TQ17@28037|Streptococcus mitis 91061|Bacilli S SnoaL-like domain - - - - - - - - - - - - SnoaL_2 NFINBLID_00202 1095738.HMPREF1047_0995 6.85e-133 380.0 COG4922@1|root,COG4922@2|Bacteria,1UY32@1239|Firmicutes,4HMCD@91061|Bacilli,1WNPR@1303|Streptococcus oralis 91061|Bacilli S SnoaL-like polyketide cyclase - - - - - - - - - - - - SnoaL_2 NFINBLID_00203 435842.HMPREF0848_00741 7.6e-190 531.0 COG0604@1|root,COG0604@2|Bacteria,1V55H@1239|Firmicutes,4HD0S@91061|Bacilli 91061|Bacilli C alcohol dehydrogenase - - - - - - - - - - - - ADH_N,ADH_zinc_N,ADH_zinc_N_2 NFINBLID_00204 888833.HMPREF9421_1656 4.04e-163 457.0 COG1125@1|root,COG1125@2|Bacteria,1TPV8@1239|Firmicutes,4H9SI@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein proV - - ko:K05847 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - ABC_tran NFINBLID_00205 999425.HMPREF9186_01493 0.0 915.0 COG1174@1|root,COG1732@1|root,COG1174@2|Bacteria,COG1732@2|Bacteria,1TQ7D@1239|Firmicutes,4HBDR@91061|Bacilli 91061|Bacilli P ABC transporter proWX - - ko:K05845,ko:K05846 ko02010,map02010 M00209 - - ko00000,ko00001,ko00002,ko02000 3.A.1.12 - - BPD_transp_1,OpuAC NFINBLID_00206 904306.HMPREF9192_1795 4.54e-173 484.0 COG0384@1|root,COG0384@2|Bacteria,1TPPX@1239|Firmicutes,4HDAC@91061|Bacilli 91061|Bacilli S Phenazine biosynthesis protein - - - - - - - - - - - - PhzC-PhzF NFINBLID_00207 864567.HMPREF8571_1560 2.67e-121 348.0 COG3275@1|root,COG3275@2|Bacteria,1V65C@1239|Firmicutes,4IEHG@91061|Bacilli,2TQ7Z@28037|Streptococcus mitis 91061|Bacilli T Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - NFINBLID_00208 1282664.H354_02523 4.17e-168 472.0 COG0619@1|root,COG0619@2|Bacteria,1UYQQ@1239|Firmicutes,4HFDP@91061|Bacilli 91061|Bacilli P cobalt transport - - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ NFINBLID_00209 1095738.HMPREF1047_0990 8.44e-200 553.0 COG1122@1|root,COG1122@2|Bacteria,1VTBJ@1239|Firmicutes,4HVE5@91061|Bacilli,1WNK4@1303|Streptococcus oralis 91061|Bacilli P ABC transporter - - - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran NFINBLID_00210 1114965.Spaf_1759 4.68e-191 530.0 COG1122@1|root,COG1122@2|Bacteria,1VSUE@1239|Firmicutes,4HT6W@91061|Bacilli 91061|Bacilli P ABC transporter, ATP-binding protein - - - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran NFINBLID_00211 999425.HMPREF9186_00918 1.64e-87 262.0 COG3201@1|root,COG3201@2|Bacteria,1UYDN@1239|Firmicutes,4HJE5@91061|Bacilli 91061|Bacilli H nicotinamide mononucleotide transporter pnuC - - ko:K03811 - - - - ko00000,ko02000 4.B.1.1 - - NMN_transporter NFINBLID_00212 889204.HMPREF9423_1744 8.95e-90 264.0 COG1959@1|root,COG1959@2|Bacteria,1V53C@1239|Firmicutes,4HN6G@91061|Bacilli 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - Rrf2 NFINBLID_00213 999425.HMPREF9186_00915 1.74e-227 628.0 COG0604@1|root,COG0604@2|Bacteria,1TQ0M@1239|Firmicutes,4HA8M@91061|Bacilli 91061|Bacilli C nadph quinone reductase - - - - - - - - - - - - ADH_N,ADH_zinc_N_2 NFINBLID_00214 889204.HMPREF9423_1742 6.41e-194 539.0 COG2267@1|root,COG2267@2|Bacteria,1UWGW@1239|Firmicutes,4IDYE@91061|Bacilli,43GIA@68892|Streptococcus infantis 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Abhydrolase_1 NFINBLID_00215 904306.HMPREF9192_1786 3.64e-191 532.0 COG1028@1|root,COG1028@2|Bacteria,1TRQB@1239|Firmicutes,4HAY3@91061|Bacilli 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family - - - - - - - - - - - - adh_short NFINBLID_00216 888746.HMPREF9180_1259 5.52e-48 155.0 2DD3F@1|root,2ZGBB@2|Bacteria,1W4NX@1239|Firmicutes,4I0KR@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00217 888048.HMPREF8577_1220 7.04e-75 227.0 2BS9S@1|root,32XMN@2|Bacteria,1VA8B@1239|Firmicutes 1239|Firmicutes S Protein of unknown function with HXXEE motif - - - - - - - - - - - - HXXEE NFINBLID_00218 999425.HMPREF9186_00911 8.64e-124 353.0 COG1309@1|root,COG1309@2|Bacteria,1TSUJ@1239|Firmicutes,4IPZN@91061|Bacilli 91061|Bacilli K Transcriptional regulator, TetR family - - - - - - - - - - - - TetR_C_8,TetR_N NFINBLID_00219 999425.HMPREF9186_00910 2.7e-188 526.0 COG1230@1|root,COG1230@2|Bacteria,1TR92@1239|Firmicutes,4HBCQ@91061|Bacilli 91061|Bacilli P cation diffusion facilitator family transporter czcD - - ko:K16264 - - - - ko00000,ko02000 2.A.4.1 - - Cation_efflux NFINBLID_00220 999425.HMPREF9186_00908 8.22e-248 682.0 COG0276@1|root,COG0276@2|Bacteria,1TPKF@1239|Firmicutes,4HAYG@91061|Bacilli 91061|Bacilli H Catalyzes the ferrous insertion into protoporphyrin IX hemH GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 M00121 R00310,R11329 RC01012 ko00000,ko00001,ko00002,ko01000 - - - Ferrochelatase NFINBLID_00221 264199.stu0936 8.99e-60 195.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli 91061|Bacilli E Dehydrogenase adhB - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N NFINBLID_00222 904306.HMPREF9192_1783 3.12e-131 379.0 COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,4HB2G@91061|Bacilli 91061|Bacilli E Dehydrogenase adhB - 1.1.1.1 ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N NFINBLID_00223 999425.HMPREF9186_00934 2.78e-85 251.0 COG3682@1|root,COG3682@2|Bacteria,1VEJ8@1239|Firmicutes,4HYMC@91061|Bacilli 91061|Bacilli K Copper transport repressor, CopY TcrY family copY - - - - - - - - - - - Penicillinase_R NFINBLID_00224 1316408.HSISM1_2060 3.75e-86 253.0 COG4633@1|root,COG4633@2|Bacteria,1VE0E@1239|Firmicutes,4HMFJ@91061|Bacilli 91061|Bacilli S cog cog4633 - - - - - - - - - - - - Cupredoxin_1 NFINBLID_00225 435842.HMPREF0848_00715 0.0 1379.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli 91061|Bacilli P P-type ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - Cupredoxin_1,E1-E2_ATPase,Hydrolase NFINBLID_00226 264199.stu0938 3.04e-30 110.0 COG4814@1|root,COG4814@2|Bacteria 2|Bacteria S Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 NFINBLID_00229 435842.HMPREF0848_00713 3.11e-162 455.0 COG1131@1|root,COG1131@2|Bacteria,1TQKM@1239|Firmicutes,4HBUK@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein ybhF_2 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_00230 904306.HMPREF9192_1775 4.73e-229 634.0 COG0842@1|root,COG0842@2|Bacteria,1TQG7@1239|Firmicutes,4H9MK@91061|Bacilli 91061|Bacilli V ABC transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 NFINBLID_00231 904306.HMPREF9192_1774 2.41e-141 399.0 COG1309@1|root,COG1309@2|Bacteria,1VBV2@1239|Firmicutes,4IPU4@91061|Bacilli 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N NFINBLID_00232 264199.stu0941 3.69e-182 506.0 COG2820@1|root,COG2820@2|Bacteria,1TQ71@1239|Firmicutes,4HUI7@91061|Bacilli 91061|Bacilli F Phosphorylase superfamily - - - - - - - - - - - - PNP_UDP_1 NFINBLID_00233 264199.stu0942 6.27e-140 396.0 COG0546@1|root,COG0546@2|Bacteria,1TPPZ@1239|Firmicutes,4IPIP@91061|Bacilli 91061|Bacilli S HAD hydrolase, family IA, variant 1 - - 3.1.3.18 ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 - R01334 RC00017 ko00000,ko00001,ko01000 - - - HAD_2 NFINBLID_00234 435842.HMPREF0848_00708 0.0 1427.0 COG1061@1|root,COG1061@2|Bacteria,1TRA8@1239|Firmicutes,4HCIF@91061|Bacilli 91061|Bacilli V Type III restriction enzyme, res subunit - - - - - - - - - - - - Helicase_C,ResIII NFINBLID_00235 1046629.Ssal_01070 8.94e-224 617.0 COG4607@1|root,COG4607@2|Bacteria,1UXCZ@1239|Firmicutes,4HAMP@91061|Bacilli 91061|Bacilli P ABC-type enterochelin transport system, periplasmic component - - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 NFINBLID_00236 1046629.Ssal_01071 5.25e-297 813.0 COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,4HANM@91061|Bacilli 91061|Bacilli V Mate efflux family protein dinF - - - - - - - - - - - MatE NFINBLID_00237 1046629.Ssal_01073 0.0 983.0 2DM53@1|root,31R8Y@2|Bacteria,1UK4X@1239|Firmicutes,4IU8I@91061|Bacilli 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - NFINBLID_00238 435842.HMPREF0848_00704 2.89e-221 610.0 COG1396@1|root,COG1396@2|Bacteria,1V957@1239|Firmicutes,4HJXP@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - - NFINBLID_00242 435842.HMPREF0848_00700 0.0 1023.0 COG3152@1|root,COG3152@2|Bacteria 2|Bacteria L Membrane yhaI - - - - - - - - - - - DUF805 NFINBLID_00243 435842.HMPREF0848_00699 0.0 1431.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli 91061|Bacilli S secreted protein - - - - - - - - - - - - DUF1002 NFINBLID_00244 1046629.Ssal_01074 0.0 1059.0 COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,4H9UF@91061|Bacilli 91061|Bacilli K RNA-binding protein homologous to eukaryotic snRNP FbpA - - - - - - - - - - - DUF814,FbpA NFINBLID_00245 904306.HMPREF9192_1767 3.73e-172 482.0 2B4EH@1|root,31X62@2|Bacteria,1V7WE@1239|Firmicutes,4HJ8G@91061|Bacilli 91061|Bacilli S TraX protein - - - - - - - - - - - - TraX NFINBLID_00246 904306.HMPREF9192_1766 3.79e-119 341.0 COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,4HM36@91061|Bacilli 91061|Bacilli S DJ-1 family thiJ - 3.5.1.124 ko:K03152 - - - - ko00000,ko01000,ko01002 - - - DJ-1_PfpI NFINBLID_00247 435842.HMPREF0848_00695 1.28e-184 514.0 COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,4HAU4@91061|Bacilli 91061|Bacilli C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) pyrK GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042602,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0052875,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - ko:K02823 ko00240,ko01100,map00240,map01100 - - - ko00000,ko00001 - - iYO844.BSU15530 DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1 NFINBLID_00248 435842.HMPREF0848_00694 3.79e-223 615.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HA5H@91061|Bacilli 91061|Bacilli F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 M00051 R01867,R01869 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh NFINBLID_00249 435842.HMPREF0848_00693 1.55e-158 445.0 COG0284@1|root,COG0284@2|Bacteria,1TPPH@1239|Firmicutes,4HAJ2@91061|Bacilli 91061|Bacilli F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) pyrF GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 ko:K01591 ko00240,ko01100,map00240,map01100 M00051 R00965 RC00409 ko00000,ko00001,ko00002,ko01000 - - - OMPdecase NFINBLID_00250 1046629.Ssal_01081 3.05e-145 409.0 COG0461@1|root,COG0461@2|Bacteria,1V1BZ@1239|Firmicutes,4HFV7@91061|Bacilli 91061|Bacilli F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) pyrE - 2.4.2.10 ko:K00762 ko00240,ko01100,map00240,map01100 M00051 R01870 RC00611 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15560 Pribosyltran NFINBLID_00251 435842.HMPREF0848_00691 6.7e-305 836.0 COG0154@1|root,COG0154@2|Bacteria,1TPGJ@1239|Firmicutes,4HBE7@91061|Bacilli 91061|Bacilli J Belongs to the amidase family nylA - 3.5.1.4 ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 - R02540,R03096,R03180,R03909,R05551,R05590 RC00010,RC00100,RC00950,RC01025 ko00000,ko00001,ko01000 - - - Amidase NFINBLID_00252 435842.HMPREF0848_00690 7.99e-191 531.0 COG0834@1|root,COG0834@2|Bacteria,1UHHG@1239|Firmicutes,4H9NX@91061|Bacilli 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family yckB - - ko:K02030,ko:K02424 ko02010,map02010 M00234,M00236 - - ko00000,ko00001,ko00002,ko02000,ko02035 3.A.1.3,3.A.1.3.10,3.A.1.3.14 - - SBP_bac_3 NFINBLID_00253 699248.SRA_05851 1.26e-102 302.0 COG0765@1|root,COG0765@2|Bacteria,1TQ43@1239|Firmicutes,4HCZV@91061|Bacilli 91061|Bacilli P ABC transporter (Permease yckA GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - ko:K10009 ko02010,map02010 M00234 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.10,3.A.1.3.14 - - BPD_transp_1 NFINBLID_00254 1046629.Ssal_01083 0.0 1260.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4H9VJ@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family sasH - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,Metallophos NFINBLID_00255 904306.HMPREF9192_1758 6.85e-219 605.0 COG2207@1|root,COG2207@2|Bacteria,1UZG6@1239|Firmicutes,4HCQS@91061|Bacilli 91061|Bacilli K Transcriptional regulator bglC - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC NFINBLID_00256 904306.HMPREF9192_1757 7.72e-311 849.0 COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,4HA06@91061|Bacilli 91061|Bacilli S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 mnmE - - ko:K03650 - - R08701 RC00053,RC00209,RC00870 ko00000,ko01000,ko03016 - - - MMR_HSR1,MnmE_helical,TrmE_N NFINBLID_00257 1046629.Ssal_01087 4.98e-307 838.0 COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,4H9SZ@91061|Bacilli 91061|Bacilli E (Alanine) symporter agcS - - ko:K03310 - - - - ko00000 2.A.25 - - Na_Ala_symp NFINBLID_00258 1046629.Ssal_01088 0.0 1486.0 COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,4HB12@91061|Bacilli 91061|Bacilli L ATP-dependent DNA helicase pcrA - 3.6.4.12 ko:K03657 ko03420,ko03430,map03420,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - UvrD-helicase,UvrD_C NFINBLID_00259 322159.STER_0995 1.99e-305 833.0 COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,4H9X5@91061|Bacilli 91061|Bacilli E o-acetylhomoserine metY - 2.5.1.49 ko:K01740 ko00270,ko01100,map00270,map01100 - R01287,R04859 RC00020,RC02821,RC02848 ko00000,ko00001,ko01000 - - - Cys_Met_Meta_PP NFINBLID_00260 904306.HMPREF9192_1752 3.67e-176 491.0 COG0561@1|root,COG0561@2|Bacteria,1TQTU@1239|Firmicutes,4HEHK@91061|Bacilli 91061|Bacilli S haloacid dehalogenase-like hydrolase - - - - - - - - - - - - Hydrolase_3 NFINBLID_00261 1046629.Ssal_01091 8.23e-112 321.0 COG2077@1|root,COG2077@2|Bacteria,1V474@1239|Firmicutes,4HFMW@91061|Bacilli 91061|Bacilli O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides tpx - 1.11.1.15 ko:K11065 - - - - ko00000,ko01000 - - - AhpC-TSA,Redoxin NFINBLID_00262 904306.HMPREF9192_1749 2.83e-144 407.0 COG0732@1|root,COG0732@2|Bacteria,1VQES@1239|Firmicutes,4HE4K@91061|Bacilli 91061|Bacilli V Type I restriction modification DNA specificity domain hsdS2 - - - - - - - - - - - Methylase_S NFINBLID_00263 435842.HMPREF0848_00681 2.41e-45 146.0 COG2461@1|root,COG2461@2|Bacteria 2|Bacteria P Hemerythrin HHE cation binding domain protein M1-755 - - ko:K09155 - - - - ko00000 - - - DUF1858,DUF438,Hemerythrin,PAS_10 NFINBLID_00264 1046629.Ssal_01094 4.62e-308 841.0 COG2461@1|root,COG2461@2|Bacteria,1TRD5@1239|Firmicutes,4HAAW@91061|Bacilli 91061|Bacilli S hemerythrin HHE cation binding domain XK27_04775 - - ko:K09155 - - - - ko00000 - - - DUF438,Hemerythrin,PAS_10 NFINBLID_00265 904306.HMPREF9192_1746 2.13e-188 525.0 COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,4HA9X@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs truB GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 ko:K03177,ko:K03483 - - - - ko00000,ko01000,ko03000,ko03016 - - iSB619.SA_RS06305 TruB-C_2,TruB_C_2,TruB_N NFINBLID_00266 1046629.Ssal_01096 2.86e-215 594.0 COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,4H9KE@91061|Bacilli 91061|Bacilli H Belongs to the ribF family ribF - 2.7.1.26,2.7.7.2 ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R00161,R00549 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06310 FAD_syn,Flavokinase NFINBLID_00267 904306.HMPREF9192_1744 2.07e-92 270.0 COG1393@1|root,COG1393@2|Bacteria,1V3QC@1239|Firmicutes,4HH0I@91061|Bacilli 91061|Bacilli K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress spxA - - ko:K16509 - - - - ko00000 - - - ArsC NFINBLID_00268 1046629.Ssal_01098 4.17e-60 185.0 COG4476@1|root,COG4476@2|Bacteria,1VEK8@1239|Firmicutes,4HNKR@91061|Bacilli 91061|Bacilli S Belongs to the UPF0223 family yktA - - - - - - - - - - - UPF0223 NFINBLID_00269 1046629.Ssal_01099 7.69e-183 508.0 COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,4HB92@91061|Bacilli 91061|Bacilli G Belongs to the inositol monophosphatase superfamily suhB GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 M00131 R01185,R01186,R01187 RC00078 ko00000,ko00001,ko00002,ko01000 - - - Inositol_P NFINBLID_00270 904306.HMPREF9192_1741 2.4e-313 853.0 COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,4HCHQ@91061|Bacilli 91061|Bacilli J NOL1 NOP2 sun family protein rsmF - - - - - - - - - - - Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI NFINBLID_00271 904306.HMPREF9192_1740 4.66e-199 552.0 COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,4HBEB@91061|Bacilli 91061|Bacilli P phosphate pstS GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - PBP_like_2 NFINBLID_00272 904306.HMPREF9192_1739 6.58e-201 558.0 COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,4HC9H@91061|Bacilli 91061|Bacilli P probably responsible for the translocation of the substrate across the membrane pstC GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02037 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 NFINBLID_00273 904306.HMPREF9192_1738 1.24e-200 556.0 COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,4HAKF@91061|Bacilli 91061|Bacilli P phosphate transport system permease pstA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02038 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko02000 3.A.1.7 - - BPD_transp_1 NFINBLID_00274 1046629.Ssal_01104 4.33e-192 533.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB2 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran NFINBLID_00275 1046629.Ssal_01105 2.49e-179 499.0 COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,4HAB1@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system pstB1 - 3.6.3.27 ko:K02036 ko02010,map02010 M00222 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.7 - - ABC_tran NFINBLID_00276 904306.HMPREF9192_1735 1.33e-148 419.0 COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,4HEU9@91061|Bacilli 91061|Bacilli P Plays a role in the regulation of phosphate uptake phoU - - ko:K02039 - - - - ko00000 - - - PhoU NFINBLID_00277 1046629.Ssal_01107 0.0 1648.0 COG0308@1|root,COG0308@2|Bacteria,1TR43@1239|Firmicutes,4HA20@91061|Bacilli 91061|Bacilli E aminopeptidase pepN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.2 ko:K01256 ko00480,ko01100,map00480,map01100 - R00899,R04951 RC00096,RC00141 ko00000,ko00001,ko01000,ko01002 - - - ERAP1_C,Peptidase_M1 NFINBLID_00278 1046629.Ssal_01108 1.03e-245 676.0 COG4974@1|root,COG4974@2|Bacteria,1URNQ@1239|Firmicutes,4HEPI@91061|Bacilli 91061|Bacilli D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division xerS - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase NFINBLID_00279 1046629.Ssal_01112 2.07e-237 652.0 COG0095@1|root,COG0095@2|Bacteria,1TQ5U@1239|Firmicutes,4H9P6@91061|Bacilli 91061|Bacilli H Lipoate-protein ligase lplA - 6.3.1.20 ko:K03800 ko00785,ko01100,map00785,map01100 - R07770,R07771,R11143 RC00043,RC00070,RC00090,RC00992,RC02896 ko00000,ko00001,ko01000 - - - BPL_LplA_LipB,Lip_prot_lig_C NFINBLID_00282 1046629.Ssal_01114 0.0 1478.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP - 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 - Phosphorylase NFINBLID_00283 1046629.Ssal_01115 0.0 1019.0 COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,4HCHB@91061|Bacilli 91061|Bacilli G 4-alpha-glucanotransferase malQ - 2.4.1.25 ko:K00705 ko00500,ko01100,map00500,map01100 - R05196 RC00049 ko00000,ko00001,ko01000 - GH77 - Glyco_hydro_77 NFINBLID_00284 1046629.Ssal_01116 2.15e-220 610.0 COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,4H9ZT@91061|Bacilli 91061|Bacilli K Transcriptional regulator malR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 NFINBLID_00285 1046629.Ssal_01117 7.11e-293 800.0 COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,4H9TU@91061|Bacilli 91061|Bacilli G ABC transporter malX - - ko:K15770 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - SBP_bac_8 NFINBLID_00286 904306.HMPREF9192_1726 3.68e-316 862.0 COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,4HB8H@91061|Bacilli 91061|Bacilli P ABC transporter (Permease malF - - ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 NFINBLID_00287 1046629.Ssal_01119 1.5e-193 537.0 COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,4HC5K@91061|Bacilli 91061|Bacilli P ABC transporter (Permease malG - - ko:K15772 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.16,3.A.1.1.2 - - BPD_transp_1 NFINBLID_00288 1046629.Ssal_01120 1.37e-269 738.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily msmX - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 NFINBLID_00289 904306.HMPREF9192_1723 6.81e-34 116.0 COG1826@1|root,COG1826@2|Bacteria 2|Bacteria U protein secretion tatA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - MttA_Hcf106 NFINBLID_00290 435842.HMPREF0848_00652 3.09e-159 447.0 COG0805@1|root,COG0805@2|Bacteria,1U7N7@1239|Firmicutes,4HB1U@91061|Bacilli 91061|Bacilli U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes tatC GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - ko:K03118 ko03060,ko03070,map03060,map03070 M00336 - - ko00000,ko00001,ko00002,ko02044 2.A.64 - - TatC NFINBLID_00291 904306.HMPREF9192_1721 0.0 1004.0 COG0672@1|root,COG0672@2|Bacteria,1TQIA@1239|Firmicutes,4HCJZ@91061|Bacilli 91061|Bacilli P COG0672 High-affinity Fe2 Pb2 permease ywbL - - ko:K07243 - - - - ko00000,ko02000 2.A.108.1,2.A.108.2 - - FTR1 NFINBLID_00292 904306.HMPREF9192_1720 1.6e-291 795.0 COG2837@1|root,COG2837@2|Bacteria,1UY9Y@1239|Firmicutes,4HACQ@91061|Bacilli 91061|Bacilli P peroxidase ywbN GO:0005575,GO:0005576 - ko:K07223,ko:K16301 - - - - ko00000,ko01000,ko02000 2.A.108.2.3 - iYO844.BSU38260 Dyp_perox,TAT_signal NFINBLID_00293 1046629.Ssal_01125 2.98e-190 530.0 COG2822@1|root,COG2822@2|Bacteria,1TS89@1239|Firmicutes,4HB0W@91061|Bacilli 91061|Bacilli P periplasmic lipoprotein involved in iron transport ycdO GO:0000041,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0015684,GO:0030001,GO:0051179,GO:0051234,GO:0070838,GO:0072511 - ko:K07224 - - - - ko00000,ko02000 2.A.108.2.3 - - Peptidase_M75 NFINBLID_00294 1046629.Ssal_01131 0.0 2261.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA2 - 3.2.1.1,3.2.1.41 ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 - R02108,R02111,R02112,R11262 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,Big_2,CBM_48,G5,Gram_pos_anchor,PUD,SLH,YSIRK_signal NFINBLID_00295 1046629.Ssal_01132 2.61e-46 152.0 COG0860@1|root,COG0860@2|Bacteria,1TR6H@1239|Firmicutes,4H9U6@91061|Bacilli 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase lytC_1 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3,SLH NFINBLID_00296 435842.HMPREF0848_00646 3e-61 214.0 COG0860@1|root,COG1705@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,1V5SF@1239|Firmicutes 1239|Firmicutes M N-Acetylmuramoyl-L-alanine amidase amiA - 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - AMIN,Amidase_3,Cu_amine_oxidN1 NFINBLID_00297 904306.HMPREF9192_1715 0.0 2065.0 COG0860@1|root,COG1705@1|root,COG3757@1|root,COG5263@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,COG3757@2|Bacteria,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - 3.5.1.28 ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 - - - Amidase_3,CW_binding_1,GBS_Bsp-like,Glucosaminidase,Glyco_hydro_25,Peptidase_C39_2 NFINBLID_00298 904306.HMPREF9192_1714 0.0 1083.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4H9Z5@91061|Bacilli 91061|Bacilli C Dehydrogenase lpdA - 1.8.1.4 ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 M00009,M00011,M00036,M00307,M00532 R00209,R01221,R01698,R03815,R07618,R08549 RC00004,RC00022,RC00583,RC02742,RC02833,RC02834 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 - - - Biotin_lipoyl,Pyr_redox_2,Pyr_redox_dim NFINBLID_00299 1046629.Ssal_01136 4.27e-274 756.0 COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HDFT@91061|Bacilli 91061|Bacilli C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex acoC - 2.3.1.12 ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 M00307 R00209,R02569 RC00004,RC02742,RC02857 br01601,ko00000,ko00001,ko00002,ko01000 - - - 2-oxoacid_dh,Biotin_lipoyl,E3_binding NFINBLID_00300 1046629.Ssal_01137 1.89e-230 635.0 COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli 91061|Bacilli C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit acoB - 1.2.4.1 ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C NFINBLID_00301 1046629.Ssal_01138 2.06e-234 644.0 COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,4HBEA@91061|Bacilli 91061|Bacilli C Dehydrogenase E1 component acoA - 1.2.4.1 ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 M00307 R00014,R00209,R01699,R03270 RC00004,RC00027,RC00627,RC02742,RC02744,RC02882 br01601,ko00000,ko00001,ko00002,ko01000 - - - E1_dh NFINBLID_00302 1046629.Ssal_01139 1.77e-255 705.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity hpk9 - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 NFINBLID_00303 1046629.Ssal_01140 6.49e-287 786.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity - - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - GGDEF,HATPase_c,HATPase_c_5,HD,HD_5,HisKA_3,MASE3,PAS,PAS_3,PAS_4,PAS_9,dCache_3 NFINBLID_00304 1046629.Ssal_01151 2.09e-213 618.0 COG4907@1|root,COG4907@2|Bacteria,1TS3Q@1239|Firmicutes,4HF7D@91061|Bacilli 91061|Bacilli S the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - DUF2207 NFINBLID_00305 1046629.Ssal_01152 1.4e-298 815.0 COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,4HA90@91061|Bacilli 91061|Bacilli F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily pyrC GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.3 ko:K01465 ko00240,ko01100,map00240,map01100 M00051 R01993 RC00632 ko00000,ko00001,ko00002,ko01000 - - - Amidohydro_1 NFINBLID_00306 904306.HMPREF9192_1707 2.22e-151 426.0 COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,4HBTR@91061|Bacilli 91061|Bacilli L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine ung GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 ko:K03648 ko03410,ko05340,map03410,map05340 - - - ko00000,ko00001,ko01000,ko03400 - - - UDG NFINBLID_00307 1046629.Ssal_01154 7.73e-277 758.0 COG0053@1|root,COG4994@1|root,COG0053@2|Bacteria,COG4994@2|Bacteria,1TSGY@1239|Firmicutes,4H9WP@91061|Bacilli 91061|Bacilli P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family yeaB - - - - - - - - - - - Cation_efflux,ZT_dimer NFINBLID_00308 1046629.Ssal_01155 0.0 868.0 COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,4HD0P@91061|Bacilli 91061|Bacilli M Belongs to the peptidase S11 family dacA1 - 3.4.16.4 ko:K01286 - - - - ko00000,ko01000 - - - DUF1958,Peptidase_S11 NFINBLID_00309 1046629.Ssal_01156 1.1e-193 538.0 COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,4HCHJ@91061|Bacilli 91061|Bacilli S Phospholipase, patatin family - - - - - - - - - - - - Patatin NFINBLID_00310 904306.HMPREF9192_1701 1.96e-128 367.0 COG2755@1|root,COG2755@2|Bacteria,1VHUN@1239|Firmicutes,4IPN1@91061|Bacilli 91061|Bacilli E Lysophospholipase L1 and related esterases - - - - - - - - - - - - Lipase_GDSL,Lipase_GDSL_2 NFINBLID_00311 1046629.Ssal_01158 0.0 966.0 COG0661@1|root,COG0661@2|Bacteria,1TPIV@1239|Firmicutes,4HBW3@91061|Bacilli 91061|Bacilli S unusual protein kinase ubiB - - ko:K03688 - - - - ko00000 - - - ABC1,APH NFINBLID_00312 1046629.Ssal_01159 2.26e-50 160.0 COG3937@1|root,COG3937@2|Bacteria,1VK6K@1239|Firmicutes,4HRS5@91061|Bacilli 91061|Bacilli S granule-associated protein - - - - - - - - - - - - - NFINBLID_00313 1046629.Ssal_01160 0.0 969.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family bglA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 NFINBLID_00314 1046629.Ssal_01161 8.88e-250 688.0 COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,4HGFS@91061|Bacilli 91061|Bacilli S hmm pf01594 XK27_12525 - - - - - - - - - - - AI-2E_transport NFINBLID_00315 904306.HMPREF9192_1694 2.25e-137 389.0 COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli 91061|Bacilli G Belongs to the phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 NFINBLID_00316 904306.HMPREF9192_1693 4.35e-137 388.0 COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli 91061|Bacilli G Belongs to the phosphoglycerate mutase family - - - - - - - - - - - - His_Phos_1 NFINBLID_00317 904306.HMPREF9192_1692 1.16e-140 397.0 COG0406@1|root,COG0406@2|Bacteria,1UXY8@1239|Firmicutes,4HFD9@91061|Bacilli 91061|Bacilli G Belongs to the phosphoglycerate mutase family XK27_06100 - - - - - - - - - - - His_Phos_1 NFINBLID_00318 1046629.Ssal_01165 6.71e-176 492.0 COG0561@1|root,COG0561@2|Bacteria,1V1SQ@1239|Firmicutes,4IPTG@91061|Bacilli 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase supH - - - - - - - - - - - Hydrolase_3 NFINBLID_00319 1316408.HSISM1_85 3.33e-265 726.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - - - - - - - - - - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 NFINBLID_00320 1116231.SMA_0870 2.94e-304 835.0 COG2244@1|root,COG2244@2|Bacteria,1TP7R@1239|Firmicutes,4HEKI@91061|Bacilli 91061|Bacilli S Polysaccharide biosynthesis protein - - - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C NFINBLID_00321 1116231.SMA_0869 3.94e-273 750.0 2ATWB@1|root,31JFJ@2|Bacteria,1U49M@1239|Firmicutes,4HZJD@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00322 1116231.SMA_0868 8.95e-222 611.0 COG1216@1|root,COG1216@2|Bacteria,1UYRR@1239|Firmicutes,4HEJ1@91061|Bacilli 91061|Bacilli S glycosyl transferase family 2 galnac-T15 - - ko:K07011 - - - - ko00000 - - - Glyco_tranf_2_3,Glyco_trans_2_3,Glyco_transf_7C,Glycos_transf_2 NFINBLID_00323 1116231.SMA_0867 2.71e-217 605.0 COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,4HC0S@91061|Bacilli 91061|Bacilli M Glycosyltransferase - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 NFINBLID_00324 246201.SM12261_1001 7.31e-162 461.0 COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,4HGEP@91061|Bacilli 91061|Bacilli M Stealth protein CR2, conserved region 2 wefC - - - - - - - - - - - Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4 NFINBLID_00325 862970.SAIN_1722 1.39e-212 589.0 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,4ISVG@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glyco_trans_1_2,Glycos_transf_2 NFINBLID_00326 904306.HMPREF9192_1681 4.52e-132 375.0 COG3955@1|root,COG3955@2|Bacteria,1V8R9@1239|Firmicutes,4HW77@91061|Bacilli 91061|Bacilli M Domain of unknown function (DUF1919) - - - - - - - - - - - - DUF1919 NFINBLID_00327 1116231.SMA_0863 4.55e-265 727.0 COG0438@1|root,COG0438@2|Bacteria,1TR6R@1239|Firmicutes,4HEIZ@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 1 family protein - - - - - - - - - - - - Glyco_transf_4,Glycos_transf_1 NFINBLID_00328 904306.HMPREF9192_1679 6.97e-285 778.0 COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,4IPU2@91061|Bacilli 91061|Bacilli M group 1 family protein rgpAc - - ko:K12996 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - DUF1972,Glycos_transf_1 NFINBLID_00329 264199.stu1108 0.0 873.0 COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HB3Z@91061|Bacilli 91061|Bacilli M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase cpsE - - - - - - - - - - - Bac_transf,CoA_binding_3 NFINBLID_00330 322159.STER_1068 3.77e-146 415.0 COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,4HCEN@91061|Bacilli 91061|Bacilli D COG0489 ATPases involved in chromosome partitioning cpsD - - - - - - - - - - - AAA_31 NFINBLID_00331 435842.HMPREF0848_00604 5.92e-142 403.0 COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,4HE26@91061|Bacilli 91061|Bacilli M biosynthesis protein capA - - - - - - - - - - - GNVR,Wzz NFINBLID_00332 435842.HMPREF0848_00603 7.12e-170 474.0 COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,4HDZR@91061|Bacilli 91061|Bacilli GM Capsular polysaccharide biosynthesis protein cpsB - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - - NFINBLID_00333 322159.STER_1071 6.13e-314 859.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HDRS@91061|Bacilli 91061|Bacilli K Cell envelope-like function transcriptional attenuator common domain protein cps4A - - - - - - - - - - - DNA_PPF,LytR_cpsA_psr NFINBLID_00334 1046629.Ssal_01032 9.01e-165 461.0 COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,4HADM@91061|Bacilli 91061|Bacilli F purine nucleoside phosphorylase deoD - 2.4.2.1 ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122 ko00000,ko00001,ko01000 - - - PNP_UDP_1 NFINBLID_00335 1046629.Ssal_01031 4.13e-166 464.0 COG0518@1|root,COG0518@2|Bacteria,1V97T@1239|Firmicutes,4HIKV@91061|Bacilli 91061|Bacilli F glutamine amidotransferase gat - 6.3.5.2 ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 M00050 R01230,R01231,R08244 RC00010,RC00204 ko00000,ko00001,ko00002,ko01000,ko01002 - - - GATase NFINBLID_00336 435842.HMPREF0848_00599 1.2e-203 574.0 COG0038@1|root,COG0038@2|Bacteria,1V07H@1239|Firmicutes 1239|Firmicutes P chloride clcA2 - - - - - - - - - - - Voltage_CLC NFINBLID_00339 1046629.Ssal_01029 2.92e-191 531.0 COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,4HABP@91061|Bacilli 91061|Bacilli F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate punA - 2.4.2.1,2.4.2.28 ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 M00034 R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244 RC00033,RC00063,RC00122,RC02819 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 NFINBLID_00340 435842.HMPREF0848_00597 1.41e-109 317.0 COG3797@1|root,COG3797@2|Bacteria,1V426@1239|Firmicutes,4HI2S@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1697) - - - - - - - - - - - - DUF1697 NFINBLID_00341 1046629.Ssal_01027 3e-294 802.0 COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,4H9RU@91061|Bacilli 91061|Bacilli G Phosphotransfer between the C1 and C5 carbon atoms of pentose deoB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008973,GO:0016853,GO:0016866,GO:0016868,GO:0044424,GO:0044444,GO:0044464 5.4.2.7 ko:K01839 ko00030,ko00230,map00030,map00230 - R01057,R02749 RC00408 ko00000,ko00001,ko01000 - - - Metalloenzyme NFINBLID_00342 1046629.Ssal_01026 2.79e-154 434.0 COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,4HFQ7@91061|Bacilli 91061|Bacilli G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate rpiA - 5.3.1.6 ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167,M00580 R01056 RC00434 ko00000,ko00001,ko00002,ko01000 - - - Rib_5-P_isom_A NFINBLID_00343 1046629.Ssal_01025 0.0 1222.0 COG3266@1|root,COG3266@2|Bacteria,1VU2V@1239|Firmicutes,4HU5W@91061|Bacilli 91061|Bacilli V Glucan-binding protein C - - - ko:K13732 ko05100,map05100 - - - ko00000,ko00001 - - - GbpC,Gram_pos_anchor,YSIRK_signal NFINBLID_00344 435842.HMPREF0848_00593 0.0 932.0 COG3266@1|root,COG3266@2|Bacteria,1VU2V@1239|Firmicutes,4HU5W@91061|Bacilli 91061|Bacilli V Glucan-binding protein C - - - - - - - - - - - - GbpC,Gram_pos_anchor,YSIRK_signal NFINBLID_00345 1046629.Ssal_01185 2.46e-139 393.0 COG1573@1|root,COG1573@2|Bacteria,1V1F8@1239|Firmicutes,4HFVS@91061|Bacilli 91061|Bacilli L Uracil-DNA glycosylase ung2 - - - - - - - - - - - UDG NFINBLID_00346 1046629.Ssal_01186 0.0 918.0 COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,4HC14@91061|Bacilli 91061|Bacilli E Dipeptidase pepV - 3.5.1.18 ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 M00016 R00899,R02734,R04951 RC00064,RC00090,RC00096,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 NFINBLID_00347 1046629.Ssal_01187 1.38e-37 125.0 COG1942@1|root,COG1942@2|Bacteria,1VKD5@1239|Firmicutes,4HRBS@91061|Bacilli 91061|Bacilli G Belongs to the 4-oxalocrotonate tautomerase family dmpI GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 M00569 R03966,R05389 RC01040,RC01355 ko00000,ko00001,ko00002,ko01000 - - - Tautomerase NFINBLID_00348 1046629.Ssal_01188 2.93e-114 328.0 2BWFV@1|root,32QWV@2|Bacteria,1V8UN@1239|Firmicutes,4HK47@91061|Bacilli 91061|Bacilli - - yybC - - - - - - - - - - - DUF2798 NFINBLID_00349 1046629.Ssal_01189 8.46e-98 285.0 COG0454@1|root,COG0456@2|Bacteria,1V77V@1239|Firmicutes,4HKYX@91061|Bacilli 91061|Bacilli K Gnat family XK27_03610 - - - - - - - - - - - Acetyltransf_1 NFINBLID_00350 1046629.Ssal_01190 1.82e-73 221.0 COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,4HH2W@91061|Bacilli 91061|Bacilli J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit rplT GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02887 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L20 NFINBLID_00351 1046629.Ssal_01191 2.36e-38 128.0 COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL35 family rpmI GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02916 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L35p NFINBLID_00352 1046629.Ssal_01192 1.1e-115 332.0 COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,4HI4P@91061|Bacilli 91061|Bacilli J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins infC GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - ko:K02520 - - - - ko00000,ko03012,ko03029 - - - IF3_C,IF3_N NFINBLID_00353 1046629.Ssal_01193 2.39e-155 436.0 COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,4HFZE@91061|Bacilli 91061|Bacilli F Belongs to the cytidylate kinase family. Type 1 subfamily cmk GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 ko:K00945 ko00240,ko01100,map00240,map01100 M00052 R00158,R00512,R01665 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Cytidylate_kin NFINBLID_00354 904306.HMPREF9192_1655 4.38e-37 135.0 COG1388@1|root,COG1388@2|Bacteria,1VD79@1239|Firmicutes,4HT02@91061|Bacilli 91061|Bacilli M LysM domain XK27_09115 - - - - - - - - - - - LysM NFINBLID_00355 904306.HMPREF9192_1653 2.86e-113 325.0 2FI04@1|root,349T2@2|Bacteria,1VQ5S@1239|Firmicutes,4HYC5@91061|Bacilli 91061|Bacilli S Family of unknown function (DUF5322) ebsA - - - - - - - - - - - DUF5322 NFINBLID_00356 1046629.Ssal_01196 1.48e-290 793.0 COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,4HAZE@91061|Bacilli 91061|Bacilli E Cleaves the N-terminal amino acid of tripeptides pepT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.11.4 ko:K01258 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20,Peptidase_M42 NFINBLID_00357 1046629.Ssal_01197 0.0 1292.0 COG0860@1|root,COG1705@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,1TR6H@1239|Firmicutes,4H9U6@91061|Bacilli 91061|Bacilli M N-acetylmuramoyl-L-alanine amidase lytC_1 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - - Amidase_3,SH3_3,SLH NFINBLID_00358 1046629.Ssal_01199 2.1e-122 350.0 COG0681@1|root,COG0681@2|Bacteria,1V2BJ@1239|Firmicutes,4HGCB@91061|Bacilli 91061|Bacilli U Belongs to the peptidase S26 family sipC - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 NFINBLID_00359 1046629.Ssal_01200 5.1e-283 775.0 COG0457@1|root,COG0457@2|Bacteria,1TT97@1239|Firmicutes,4HAIA@91061|Bacilli 91061|Bacilli G COG0457 FOG TPR repeat XK27_05225 - - - - - - - - - - - TPR_16,TPR_19,TPR_2,TPR_6,TPR_7,TPR_8 NFINBLID_00360 1046629.Ssal_01201 3.66e-233 647.0 COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,4H9SR@91061|Bacilli 91061|Bacilli S permease XK27_05220 - - - - - - - - - - - AI-2E_transport NFINBLID_00361 1046629.Ssal_01202 6.84e-118 336.0 COG1051@1|root,COG1051@2|Bacteria,1V66I@1239|Firmicutes,4HHRE@91061|Bacilli 91061|Bacilli F NTP pyrophosphohydrolases including oxidative damage repair enzymes mutX - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX NFINBLID_00362 904306.HMPREF9192_1646 2.42e-210 582.0 COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,4HA5A@91061|Bacilli 91061|Bacilli D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation ftsX - - ko:K09811 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - FtsX NFINBLID_00363 264199.stu1145 1.04e-159 448.0 COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,4H9Z2@91061|Bacilli 91061|Bacilli D cell division ATP-binding protein FtsE ftsE - - ko:K09812 ko02010,map02010 M00256 - - ko00000,ko00001,ko00002,ko02000,ko03036 3.A.1.140 - - ABC_tran NFINBLID_00364 1046629.Ssal_01205 1.08e-231 638.0 COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,4H9N2@91061|Bacilli 91061|Bacilli J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA prfB - - ko:K02836 - - - - ko00000,ko03012 - - - PCRF,RF-1 NFINBLID_00365 1046629.Ssal_01206 2.74e-266 729.0 COG1600@1|root,COG1600@2|Bacteria,1TP6Q@1239|Firmicutes,4HAEW@91061|Bacilli 91061|Bacilli C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) queG GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 ko:K18979 - - - - ko00000,ko01000,ko03016 - - - DUF1730,Fer4_16,HEAT_2 NFINBLID_00366 1046629.Ssal_01207 8.97e-197 546.0 COG1409@1|root,COG1409@2|Bacteria,1V9B5@1239|Firmicutes,4HJX0@91061|Bacilli 91061|Bacilli S Calcineurin-like phosphoesterase - - - - - - - - - - - - Metallophos NFINBLID_00367 1046629.Ssal_01208 5.8e-167 468.0 COG0778@1|root,COG0778@2|Bacteria,1UB8S@1239|Firmicutes,4HEGP@91061|Bacilli 91061|Bacilli C nitroreductase nfrA - 1.5.1.38 ko:K19285 ko00740,ko01100,map00740,map01100 - R05706 RC00126 ko00000,ko00001,ko01000 - - - Nitroreductase NFINBLID_00368 1046629.Ssal_01209 0.0 1617.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli 91061|Bacilli P cation transport ATPase pacL - 3.6.3.8 ko:K01537 - - - - ko00000,ko01000 3.A.3.2 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase NFINBLID_00369 1046629.Ssal_01211 1.39e-88 259.0 COG4506@1|root,COG4506@2|Bacteria 2|Bacteria S Domain of unknown function (DUF1934) ywiB - - - - - - - - - - - DUF1934 NFINBLID_00370 1046629.Ssal_01213 3.68e-180 504.0 COG0454@1|root,COG0456@2|Bacteria,1VD7Z@1239|Firmicutes,4HGYD@91061|Bacilli 91061|Bacilli K Acetyltransferase GNAT family XK27_00115 - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 NFINBLID_00371 904306.HMPREF9192_1636 2.3e-188 523.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HCZ6@91061|Bacilli 91061|Bacilli S hydrolases of the HAD superfamily XK27_00835 - - - - - - - - - - - Hydrolase_3 NFINBLID_00372 904306.HMPREF9192_1635 5.57e-289 789.0 COG2348@1|root,COG2348@2|Bacteria,1TRZU@1239|Firmicutes,4HC1Z@91061|Bacilli 91061|Bacilli V protein involved in methicillin resistance femX - 2.3.2.10,2.3.2.16 ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 - R08776,R08779 RC00055,RC00096 ko00000,ko00001,ko01000,ko01011 - - - FemAB NFINBLID_00373 435842.HMPREF0848_00563 4.46e-74 222.0 COG2832@1|root,COG2832@2|Bacteria,1VC3R@1239|Firmicutes,4HMWE@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF454) - - - ko:K09790 - - - - ko00000 - - - DUF454 NFINBLID_00374 1046629.Ssal_01219 8.43e-196 542.0 COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,4HAKD@91061|Bacilli 91061|Bacilli S Metal-dependent hydrolases of the beta-lactamase superfamily I vicX - 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 NFINBLID_00375 1046629.Ssal_01220 1.44e-310 847.0 COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,4HA52@91061|Bacilli 91061|Bacilli T Histidine kinase vicK - 2.7.13.3 ko:K07652 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HAMP,HATPase_c,HisKA,PAS,PAS_9 NFINBLID_00376 904306.HMPREF9192_1631 4.13e-165 462.0 COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,4HA8Q@91061|Bacilli 91061|Bacilli KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain yycF GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K07668 ko02020,map02020 M00459 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C NFINBLID_00377 904306.HMPREF9192_1626 1.1e-179 500.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - - ko:K10041 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran NFINBLID_00378 1046629.Ssal_01223 1.74e-187 522.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HAHV@91061|Bacilli 91061|Bacilli ET ABC-type amino acid transport signal transduction systems, periplasmic component domain peb1A - - ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 M00228,M00232,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8 - - SBP_bac_3 NFINBLID_00379 904306.HMPREF9192_1624 1.27e-153 432.0 COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HE9C@91061|Bacilli 91061|Bacilli P ABC transporter (Permease XK27_07620 - - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 NFINBLID_00380 1046629.Ssal_01225 1.75e-143 405.0 COG0765@1|root,COG0765@2|Bacteria,1V14N@1239|Firmicutes,4HJ9W@91061|Bacilli 91061|Bacilli P ABC transporter (permease) - - - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 NFINBLID_00381 904306.HMPREF9192_1626 3.67e-178 496.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - - ko:K10041 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran NFINBLID_00382 904306.HMPREF9192_1625 7.92e-184 513.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes 1239|Firmicutes ET Belongs to the bacterial solute-binding protein 3 family peb1A - - ko:K10039 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 NFINBLID_00383 904306.HMPREF9192_1624 4.8e-158 444.0 COG0765@1|root,COG0765@2|Bacteria,1TQ5K@1239|Firmicutes,4HE9C@91061|Bacilli 91061|Bacilli P ABC transporter (Permease XK27_07620 - - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 NFINBLID_00384 1046629.Ssal_01225 5.84e-142 402.0 COG0765@1|root,COG0765@2|Bacteria,1V14N@1239|Firmicutes,4HJ9W@91061|Bacilli 91061|Bacilli P ABC transporter (permease) - - - ko:K10040 ko02010,map02010 M00228 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 NFINBLID_00385 904306.HMPREF9192_1622 1.49e-196 546.0 COG2169@1|root,COG2169@2|Bacteria,1V4X2@1239|Firmicutes,4HIF5@91061|Bacilli 91061|Bacilli F DNA RNA non-specific endonuclease endA - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2,Endonuclease_NS NFINBLID_00386 1046629.Ssal_01228 2.03e-35 120.0 2EK0E@1|root,33DQZ@2|Bacteria,1VMAH@1239|Firmicutes,4HRG1@91061|Bacilli 91061|Bacilli S DNA-directed RNA polymerase subunit beta - - - - - - - - - - - - EpuA NFINBLID_00387 1046629.Ssal_01229 3.97e-294 804.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA - 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - - EPSP_synthase NFINBLID_00388 435842.HMPREF0848_00551 3.91e-248 682.0 COG3405@1|root,COG3405@2|Bacteria,1VCBY@1239|Firmicutes,4IPTW@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - - - - - - - - - - Glyco_hydro_8 NFINBLID_00389 435842.HMPREF0848_00550 1.45e-314 857.0 COG1215@1|root,COG1215@2|Bacteria,1TRCI@1239|Firmicutes,4HAAK@91061|Bacilli 91061|Bacilli M Glycosyltransferases, probably involved in cell wall biogenesis ydaM - - - - - - - - - - - Glyco_tranf_2_3 NFINBLID_00391 435842.HMPREF0848_00549 1.58e-169 475.0 2DSSB@1|root,33H90@2|Bacteria,1W0IB@1239|Firmicutes,4HYWM@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00392 435842.HMPREF0848_00548 6.58e-275 752.0 COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,4HBI3@91061|Bacilli 91061|Bacilli G Belongs to the UDP-N-acetylglucosamine 2-epimerase family mnaA - 5.1.3.14 ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 M00362 R00420 RC00290 ko00000,ko00001,ko00002,ko01000,ko01005 - - iSB619.SA_RS11005 Epimerase_2 NFINBLID_00393 435842.HMPREF0848_00547 3.47e-268 736.0 COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,4HB33@91061|Bacilli 91061|Bacilli H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme metK GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 M00034,M00035,M00368,M00609 R00177,R04771 RC00021,RC01211 ko00000,ko00001,ko00002,ko01000 - - - S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N NFINBLID_00394 1046629.Ssal_01240 1.54e-219 606.0 COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,4HB60@91061|Bacilli 91061|Bacilli HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor birA - 6.3.4.15 ko:K03524 ko00780,ko01100,map00780,map01100 - R01074,R05145 RC00043,RC00070,RC00096,RC02896 ko00000,ko00001,ko01000,ko03000 - - - BPL_C,BPL_LplA_LipB,HTH_11 NFINBLID_00395 1046629.Ssal_01242 0.0 1035.0 COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,4HAUE@91061|Bacilli 91061|Bacilli L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity dnaX - 2.7.7.7 ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNA_pol3_gamma3 NFINBLID_00396 1046629.Ssal_01243 4.9e-111 320.0 COG1956@1|root,COG1956@2|Bacteria,1V6GQ@1239|Firmicutes,4HH7X@91061|Bacilli 91061|Bacilli T GAF domain-containing protein ytsP - 1.8.4.14 ko:K08968 ko00270,map00270 - R02025 RC00639 ko00000,ko00001,ko01000 - - - GAF_2 NFINBLID_00397 1046629.Ssal_01244 1.34e-204 567.0 COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,4HAVW@91061|Bacilli 91061|Bacilli J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) miaA GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 - R01122 RC02820 ko00000,ko00001,ko01000,ko01006,ko03016 - - - IPPT NFINBLID_00398 1046629.Ssal_01245 9.42e-28 100.0 2C91M@1|root,33E1E@2|Bacteria,1VPEZ@1239|Firmicutes,4HRR2@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3042) WQ51_02665 - - - - - - - - - - - DUF3042 NFINBLID_00401 1046629.Ssal_01252 2.33e-74 223.0 COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,4HIK3@91061|Bacilli 91061|Bacilli J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site rplS GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02884 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L19 NFINBLID_00402 1046629.Ssal_01253 1.77e-264 728.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes 1239|Firmicutes P Chloride transporter ClC family eriC - - ko:K03281 - - - - ko00000 2.A.49 - - Voltage_CLC NFINBLID_00403 264199.stu1181 9.78e-52 164.0 COG1605@1|root,COG1605@2|Bacteria 2|Bacteria E Chorismate mutase pheA GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,2.3.1.79,4.2.1.51,5.4.99.5 ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00024,M00025 R00691,R01373,R01715,R01728 RC00125,RC00360,RC03116 ko00000,ko00001,ko00002,ko01000 - - iECNA114_1301.ECNA114_2667 ACT,CM_2,PDT NFINBLID_00404 1046629.Ssal_01255 0.0 963.0 COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,4HD2H@91061|Bacilli 91061|Bacilli P Chloride transporter, ClC family eriC - - ko:K03281 - - - - ko00000 2.A.49 - - TrkA_C,Voltage_CLC NFINBLID_00405 435842.HMPREF0848_00535 2.86e-97 283.0 COG0716@1|root,COG0716@2|Bacteria,1V7AG@1239|Firmicutes,4HMJF@91061|Bacilli 91061|Bacilli C Flavodoxin ykuP - - ko:K03839 - - - - ko00000 - - - Flavodoxin_1 NFINBLID_00406 996306.SSUR61_0275 7.17e-26 100.0 29R1H@1|root,30C2M@2|Bacteria,1U92D@1239|Firmicutes,4IJ2X@91061|Bacilli,1WTJN@1307|Streptococcus suis 91061|Bacilli - - XK27_08880 - - - - - - - - - - - - NFINBLID_00407 1046629.Ssal_01259 3.12e-162 455.0 COG5549@1|root,COG5549@2|Bacteria,1VW9X@1239|Firmicutes,4HWF8@91061|Bacilli 91061|Bacilli O Zinc-dependent metalloprotease XK27_08875 - - - - - - - - - - - Peptidase_M10 NFINBLID_00408 1046629.Ssal_01260 4.87e-190 527.0 COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,4HD64@91061|Bacilli 91061|Bacilli S Esterase estA - - ko:K03930 - - - - ko00000,ko01000 - CE1 - Esterase NFINBLID_00409 1046629.Ssal_01262 0.0 1064.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjB GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL NFINBLID_00410 1046629.Ssal_01263 3.8e-174 486.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein XK27_08845 - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran NFINBLID_00411 1046629.Ssal_01264 1.37e-190 531.0 COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,4HBMY@91061|Bacilli 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family XK27_08840 - - ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - BPD_transp_2 NFINBLID_00412 1046629.Ssal_01265 6.84e-229 631.0 COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,4HE7G@91061|Bacilli 91061|Bacilli S ABC transporter substrate binding protein - - - ko:K01989 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind NFINBLID_00414 888048.HMPREF8577_0634 1.94e-266 808.0 COG2373@1|root,COG2373@2|Bacteria,1TV1Y@1239|Firmicutes,4HBHJ@91061|Bacilli 91061|Bacilli Q the current gene model (or a revised gene model) may contain a frame shift crpB - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal NFINBLID_00415 888833.HMPREF9421_1411 3.22e-130 420.0 COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1TV1Y@1239|Firmicutes,4HBHJ@91061|Bacilli 91061|Bacilli Q the current gene model (or a revised gene model) may contain a frame shift crpB - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal NFINBLID_00416 888833.HMPREF9421_1411 0.0 3646.0 COG2373@1|root,COG2931@1|root,COG2373@2|Bacteria,COG2931@2|Bacteria,1TV1Y@1239|Firmicutes,4HBHJ@91061|Bacilli 91061|Bacilli Q the current gene model (or a revised gene model) may contain a frame shift crpB - - - - - - - - - - - Gram_pos_anchor,YSIRK_signal NFINBLID_00417 1046629.Ssal_01268 0.0 958.0 COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,4H9VY@91061|Bacilli 91061|Bacilli G Belongs to the pyruvate kinase family pyk GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 M00001,M00002,M00049,M00050 R00200,R00430,R01138,R01858,R02320 RC00002,RC00015 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - PEP-utilizers,PK,PK_C NFINBLID_00418 1046629.Ssal_01270 1.92e-238 656.0 COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,4HAPN@91061|Bacilli 91061|Bacilli F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis pfkA GO:0003674,GO:0003824,GO:0003872,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008443,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061615,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.11 ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 M00001,M00345 R00756,R03236,R03237,R03238,R03239,R04779 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 - - iYO844.BSU29190 PFK NFINBLID_00419 1046629.Ssal_01271 0.0 1985.0 COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,4H9T3@91061|Bacilli 91061|Bacilli L DNA polymerase dnaE - 2.7.7.7 ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon NFINBLID_00420 1046629.Ssal_01272 6.51e-145 407.0 COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,4HFTY@91061|Bacilli 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuD - 4.2.1.33,4.2.1.35 ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R10170 RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase_C NFINBLID_00421 1046629.Ssal_01273 0.0 948.0 COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,4HAWA@91061|Bacilli 91061|Bacilli E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate leuC - 4.2.1.33,4.2.1.35 ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 M00432,M00535 R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170 RC00497,RC00976,RC00977,RC01041,RC01046,RC03072 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10700 Aconitase NFINBLID_00422 1046629.Ssal_01275 7.84e-241 662.0 COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,4HATP@91061|Bacilli 91061|Bacilli CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate leuB GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 M00432,M00535 R00994,R04426,R10052 RC00084,RC00417,RC03036 br01601,ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU28270 Iso_dh NFINBLID_00423 435842.HMPREF0848_00511 0.0 998.0 COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,4HA6E@91061|Bacilli 91061|Bacilli E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) leuA - 2.3.3.13 ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 M00432 R01213 RC00004,RC00470,RC02754 br01601,ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS10690,iYO844.BSU28280 HMGL-like,LeuA_dimer NFINBLID_00424 997830.HMPREF1124_2001 2.15e-169 472.0 COG0588@1|root,COG0588@2|Bacteria,1TQFP@1239|Firmicutes,4HAW7@91061|Bacilli,43G3N@68892|Streptococcus infantis 91061|Bacilli G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate gpmA GO:0001871,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009986,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031,GO:2001065 5.4.2.11 ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 M00001,M00002,M00003 R01518 RC00536 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - His_Phos_1 NFINBLID_00425 1046629.Ssal_01281 2.05e-228 628.0 COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,4HBFE@91061|Bacilli 91061|Bacilli F Catalyzes the conversion of dihydroorotate to orotate pyrD GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.5.2,1.3.98.1 ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 M00051 R01867,R01868 RC00051 ko00000,ko00001,ko00002,ko01000 - - - DHO_dh NFINBLID_00427 1046629.Ssal_01283 3.1e-52 165.0 COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,4HKF2@91061|Bacilli 91061|Bacilli L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions hup - - ko:K03530 - - - - ko00000,ko03032,ko03036,ko03400 - - - Bac_DNA_binding NFINBLID_00428 1046629.Ssal_01284 9.19e-124 353.0 COG4698@1|root,COG4698@2|Bacteria,1VF0K@1239|Firmicutes,4HIYN@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria ypmS - - - - - - - - - - - DUF2140 NFINBLID_00429 1046629.Ssal_01285 1.02e-202 561.0 COG2755@1|root,COG2755@2|Bacteria,1V1HR@1239|Firmicutes,4HDXS@91061|Bacilli 91061|Bacilli E COG2755 Lysophospholipase L1 and related esterases XK27_03630 - - - - - - - - - - - Lipase_GDSL_2 NFINBLID_00430 1046629.Ssal_01286 1.04e-185 518.0 COG1307@1|root,COG1307@2|Bacteria,1TRZ4@1239|Firmicutes,4HBR8@91061|Bacilli 91061|Bacilli S DegV family WQ51_01275 - - - - - - - - - - - DegV NFINBLID_00431 1046629.Ssal_01287 0.0 1042.0 COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,4H9ZR@91061|Bacilli 91061|Bacilli L May be involved in recombinational repair of damaged DNA recN GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03631 - - - - ko00000,ko03400 - - - AAA_23,SMC_N NFINBLID_00432 1046629.Ssal_01288 1.26e-96 281.0 COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,4HFY8@91061|Bacilli 91061|Bacilli K Regulates arginine biosynthesis genes argR2 - - ko:K03402 - - - - ko00000,ko03000 - - - Arg_repressor,Arg_repressor_C NFINBLID_00433 1046629.Ssal_01289 1.89e-190 529.0 COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,4HAPY@91061|Bacilli 91061|Bacilli J Ribosomal RNA large subunit methyltransferase J rrmJ - 2.1.1.226,2.1.1.227 ko:K06442 - - - - ko00000,ko01000,ko03009 - - - FtsJ,S4 NFINBLID_00434 1046629.Ssal_01290 6.13e-199 552.0 COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,4HA8E@91061|Bacilli 91061|Bacilli H Belongs to the FPP GGPP synthase family ispA GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00364,M00366 R01658,R02003,R02061 RC00279 ko00000,ko00001,ko00002,ko01000,ko01006 - - - polyprenyl_synt NFINBLID_00435 1046629.Ssal_01291 3.47e-40 133.0 COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,4HNRB@91061|Bacilli 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseB - 3.1.11.6 ko:K03602 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_S NFINBLID_00436 1046629.Ssal_01292 3.31e-292 800.0 COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,4HAN2@91061|Bacilli 91061|Bacilli L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides xseA - 3.1.11.6 ko:K03601 ko03430,map03430 - - - ko00000,ko00001,ko01000,ko03400 - - - Exonuc_VII_L,tRNA_anti_2 NFINBLID_00438 1046629.Ssal_01295 1.51e-152 428.0 COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,4HATD@91061|Bacilli 91061|Bacilli L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate nth - 4.2.99.18 ko:K10773 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD NFINBLID_00439 1046629.Ssal_01296 2.59e-162 454.0 COG3935@1|root,COG3935@2|Bacteria 2|Bacteria - - dnaD - - ko:K02086 - - - - ko00000 - - - DnaB_2 NFINBLID_00440 1046629.Ssal_01297 1.63e-231 636.0 COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,4H9W4@91061|Bacilli 91061|Bacilli E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine metA GO:0003674,GO:0003824,GO:0008374,GO:0008899,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750 2.3.1.46 ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 M00017 R01777 RC00004,RC00041 ko00000,ko00001,ko00002,ko01000 - - - HTS NFINBLID_00441 904306.HMPREF9192_1561 6.18e-120 342.0 COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,4HFUA@91061|Bacilli 91061|Bacilli F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis apt GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 ko:K00759 ko00230,ko01100,map00230,map01100 - R00190,R01229,R04378 RC00063 ko00000,ko00001,ko01000,ko04147 - - - Pribosyltran NFINBLID_00442 1046629.Ssal_01299 0.0 1404.0 COG0608@1|root,COG4199@1|root,COG0608@2|Bacteria,COG4199@2|Bacteria,1TPXE@1239|Firmicutes,4H9UP@91061|Bacilli 91061|Bacilli L Single-stranded-DNA-specific exonuclease recj recJ - - ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1,ssDNA-exonuc_C NFINBLID_00443 999425.HMPREF9186_00583 5.13e-87 256.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase GnaT - 2.5.1.16 ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 M00034,M00133 R01920,R02869,R08359 RC00021,RC00053 ko00000,ko00001,ko00002,ko01000 - - - Acetyltransf_1,Acetyltransf_10 NFINBLID_00444 1046629.Ssal_01301 1.95e-159 447.0 COG0500@1|root,COG0500@2|Bacteria,1V1BN@1239|Firmicutes,4HPJN@91061|Bacilli 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_23 NFINBLID_00445 904306.HMPREF9192_1558 1.43e-175 490.0 COG0300@1|root,COG0300@2|Bacteria,1TSJ3@1239|Firmicutes,4HDU5@91061|Bacilli 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family yqjQ - - ko:K07124 - - - - ko00000 - - - adh_short NFINBLID_00446 904306.HMPREF9192_1557 2.57e-221 610.0 COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,4HABM@91061|Bacilli 91061|Bacilli S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA rnz GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 ko:K00784 ko03013,map03013 - - - ko00000,ko00001,ko01000,ko03016 - - - Lactamase_B,Lactamase_B_2 NFINBLID_00447 904306.HMPREF9192_1556 4.84e-144 407.0 COG4468@1|root,COG4468@2|Bacteria,1VY8D@1239|Firmicutes,4HXPD@91061|Bacilli 91061|Bacilli G UDPglucose--hexose-1-phosphate uridylyltransferase XK27_05445 - - - - - - - - - - - - NFINBLID_00448 1046629.Ssal_01305 1.44e-311 850.0 COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,4HACA@91061|Bacilli 91061|Bacilli S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis hflX GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - ko:K03665 - - - - ko00000,ko03009 - - - GTP-bdg_M,GTP-bdg_N,MMR_HSR1 NFINBLID_00449 904306.HMPREF9192_1554 9.57e-294 807.0 COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,4HAV4@91061|Bacilli 91061|Bacilli D Belongs to the SEDS family rodA - - ko:K05837 - - - - ko00000,ko03036 - - - FTSW_RODA_SPOVE NFINBLID_00450 1046629.Ssal_01307 0.0 2935.0 COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli 91061|Bacilli M KxYKxGKxW signal domain protein - - 2.4.1.5 ko:K00689 ko00500,ko02020,map00500,map02020 - R02120,R06066 RC00028 ko00000,ko00001,ko01000 - GH13 - Big_2,CW_binding_1,Glyco_hydro_70 NFINBLID_00451 435842.HMPREF0848_00471 0.0 2690.0 COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli 91061|Bacilli M KxYKxGKxW signal domain protein - - 2.4.1.5 ko:K00689 ko00500,ko02020,map00500,map02020 - R02120,R06066 RC00028 ko00000,ko00001,ko01000 - GH13 - Big_2,CW_binding_1,Glyco_hydro_70 NFINBLID_00452 1046629.Ssal_01309 0.0 2634.0 COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli 91061|Bacilli M KxYKxGKxW signal domain protein - - 2.4.1.5 ko:K00689 ko00500,ko02020,map00500,map02020 - R02120,R06066 RC00028 ko00000,ko00001,ko01000 - GH13 - Big_2,CW_binding_1,Glyco_hydro_70 NFINBLID_00453 1046629.Ssal_01310 1.99e-220 610.0 COG1216@1|root,COG2246@1|root,COG1216@2|Bacteria,COG2246@2|Bacteria,1UIHV@1239|Firmicutes,4ISID@91061|Bacilli 91061|Bacilli M glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,GtrA NFINBLID_00454 904306.HMPREF9192_1548 5.93e-159 461.0 arCOG08054@1|root,2Z8AD@2|Bacteria,1TZ8N@1239|Firmicutes,4HV65@91061|Bacilli 91061|Bacilli S Carbohydrate-binding domain-containing protein Cthe_2159 - - - - - - - - - - - - Cthe_2159 NFINBLID_00455 435842.HMPREF0848_00461 7.71e-182 506.0 COG5036@1|root,COG5036@2|Bacteria,1V1FZ@1239|Firmicutes,4HJFI@91061|Bacilli 91061|Bacilli P molecular chaperone - - - - - - - - - - - - VTC NFINBLID_00456 435842.HMPREF0848_00460 2.54e-133 381.0 COG1285@1|root,COG1285@2|Bacteria,1V1GI@1239|Firmicutes 1239|Firmicutes S Psort location CytoplasmicMembrane, score XK27_05505 - - - - - - - - - - - DUF4956 NFINBLID_00458 1046629.Ssal_01315 1.27e-66 202.0 COG0140@1|root,COG0140@2|Bacteria 2|Bacteria E phosphoribosyl-ATP diphosphatase activity hisE GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037,R04640 RC00002,RC00945,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH NFINBLID_00459 904306.HMPREF9192_1544 1.94e-76 228.0 COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,4HA9R@91061|Bacilli 91061|Bacilli E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP hisI - 3.5.4.19,3.6.1.31 ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04035,R04037 RC00002,RC01055 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14110,iYO844.BSU34860 PRA-CH,PRA-PH NFINBLID_00460 435842.HMPREF0848_00457 9.34e-175 488.0 COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,4HAAM@91061|Bacilli 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit hisF GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14115 His_biosynth NFINBLID_00461 1046629.Ssal_01319 9.72e-166 464.0 COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,4HACP@91061|Bacilli 91061|Bacilli E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase hisA GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04640 RC00945 ko00000,ko00001,ko00002,ko01000 - - - His_biosynth NFINBLID_00462 435842.HMPREF0848_00455 1.3e-138 392.0 COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,4HHNQ@91061|Bacilli 91061|Bacilli E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR hisH - - ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R04558 RC00010,RC01190,RC01943 ko00000,ko00001,ko00002,ko01000 - - - GATase NFINBLID_00463 1046629.Ssal_01321 3.35e-137 388.0 COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,4HCFG@91061|Bacilli 91061|Bacilli E imidazoleglycerol-phosphate dehydratase hisB GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03457 RC00932 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS14130 IGPD NFINBLID_00464 1046629.Ssal_01322 4.35e-300 819.0 COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,4H9XK@91061|Bacilli 91061|Bacilli E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine hisD GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01158,R01163,R03012 RC00099,RC00242,RC00463 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU34910 Histidinol_dh NFINBLID_00465 1046629.Ssal_01323 2.93e-151 425.0 COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,4H9MH@91061|Bacilli 91061|Bacilli E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity hisG GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002,ko01000 - - - HisG,tRNA-synt_His NFINBLID_00466 435842.HMPREF0848_00451 1.19e-230 635.0 COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,4HBBA@91061|Bacilli 91061|Bacilli E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine hisZ - - ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R01071 RC02819,RC03200 ko00000,ko00001,ko00002 - - - tRNA-synt_His NFINBLID_00467 435842.HMPREF0848_00450 3.09e-245 674.0 COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,4HA1H@91061|Bacilli 91061|Bacilli E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily hisC - 2.6.1.9 ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 M00026 R00694,R00734,R03243 RC00006,RC00888 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 NFINBLID_00468 435842.HMPREF0848_00449 2.69e-78 234.0 2EJUK@1|root,33DJ8@2|Bacteria,1VM50@1239|Firmicutes 1239|Firmicutes - - XK27_08085 - - - - - - - - - - - - NFINBLID_00469 435842.HMPREF0848_00448 6.52e-198 551.0 COG4632@1|root,COG4632@2|Bacteria,1TR6Z@1239|Firmicutes,4HGB0@91061|Bacilli 91061|Bacilli G Exopolysaccharide biosynthesis protein XK27_08080 - - - - - - - - - - - NAGPA NFINBLID_00470 904306.HMPREF9192_1539 3.97e-173 483.0 COG1387@1|root,COG1387@2|Bacteria,1V77D@1239|Firmicutes,4HGYX@91061|Bacilli 91061|Bacilli E Histidinol phosphatase and related hydrolases of the PHP family hisJ - 3.1.3.15 ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 M00026 R03013 RC00017 ko00000,ko00001,ko00002,ko01000 - - - - NFINBLID_00471 435842.HMPREF0848_00440 1.77e-151 426.0 COG4478@1|root,COG4478@2|Bacteria,1VGZ1@1239|Firmicutes,4HNTM@91061|Bacilli 91061|Bacilli S tigr01906 - - - - - - - - - - - - DUF1461 NFINBLID_00472 1046629.Ssal_01330 7.4e-179 498.0 COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,4HA3R@91061|Bacilli 91061|Bacilli G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro nagD - 3.1.3.41 ko:K01101 ko00627,ko01120,map00627,map01120 - R03024 RC00151 ko00000,ko00001,ko01000 - - - Hydrolase_6,Hydrolase_like NFINBLID_00473 1046629.Ssal_01331 1.69e-179 499.0 COG3884@1|root,COG3884@2|Bacteria,1V3RB@1239|Firmicutes,4HHJ4@91061|Bacilli 91061|Bacilli I Acyl-ACP thioesterase fat - 3.1.2.21 ko:K01071 ko00061,ko01100,map00061,map01100 - R04014,R08157,R08158 RC00014,RC00039 ko00000,ko00001,ko01000,ko01004 - - - Acyl-ACP_TE NFINBLID_00474 264199.stu1236 1.49e-273 748.0 COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,4HA60@91061|Bacilli 91061|Bacilli H Involved in the biosynthesis of porphyrin-containing compound hemN GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - - - - - - - - - - HemN_C,Radical_SAM NFINBLID_00477 435842.HMPREF0848_00434 5.48e-263 719.0 COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,4HA3Y@91061|Bacilli 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily rfbB GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 4.2.1.46 ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 M00793 R06513 RC00402 ko00000,ko00001,ko00002,ko01000 - - - GDP_Man_Dehyd NFINBLID_00478 1046629.Ssal_01338 2.36e-143 404.0 COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,4HFQB@91061|Bacilli 91061|Bacilli M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose rmlC - 5.1.3.13 ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R06514 RC01531 ko00000,ko00001,ko00002,ko01000 - - - dTDP_sugar_isom NFINBLID_00479 1046629.Ssal_01339 7.83e-206 569.0 COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,4H9R0@91061|Bacilli 91061|Bacilli M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis rfbA - 2.7.7.24 ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 M00793 R02328 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase NFINBLID_00480 1046629.Ssal_01340 0.0 888.0 COG4099@1|root,COG4099@2|Bacteria,1TRER@1239|Firmicutes,4IQ64@91061|Bacilli 91061|Bacilli S phospholipase Carboxylesterase - - - - - - - - - - - - Esterase_phd,Peptidase_S9 NFINBLID_00481 1046629.Ssal_01341 9.57e-246 676.0 COG0665@1|root,COG0665@2|Bacteria,1TQTF@1239|Firmicutes,4HA0F@91061|Bacilli 91061|Bacilli E oxidoreductase yurR - 1.4.5.1 ko:K00285 ko00360,map00360 - R01374,R09493 RC00006,RC00025 ko00000,ko00001,ko01000 - - - DAO NFINBLID_00482 1046629.Ssal_01342 3.03e-112 327.0 COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,4HB3R@91061|Bacilli 91061|Bacilli P Mediates zinc uptake. May also transport other divalent cations zupT - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip NFINBLID_00483 1046629.Ssal_01342 6.54e-42 145.0 COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,4HB3R@91061|Bacilli 91061|Bacilli P Mediates zinc uptake. May also transport other divalent cations zupT - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip NFINBLID_00484 1046629.Ssal_01343 6.85e-182 506.0 COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,4H9NY@91061|Bacilli 91061|Bacilli S Belongs to the GTP cyclohydrolase I type 2 NIF3 family yqfO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - NIF3 NFINBLID_00485 904306.HMPREF9192_1525 1.13e-154 435.0 COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,4HHIM@91061|Bacilli 91061|Bacilli S SAM-dependent methyltransferase trmK GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.217 ko:K06967 - - - - ko00000,ko01000,ko03016 - - - TrmK NFINBLID_00486 1046629.Ssal_01345 5.03e-84 249.0 COG2246@1|root,COG2246@2|Bacteria,1VMS6@1239|Firmicutes,4HNB7@91061|Bacilli 91061|Bacilli S GtrA-like protein mesH - - - - - - - - - - - GtrA NFINBLID_00487 1046629.Ssal_01346 1.85e-315 860.0 COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,4HB16@91061|Bacilli 91061|Bacilli G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate glmM - 5.4.2.10 ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 - R02060 RC00408 ko00000,ko00001,ko01000 - - iSB619.SA_RS11275 PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV NFINBLID_00488 1046629.Ssal_01347 3.03e-210 583.0 COG4856@1|root,COG4856@2|Bacteria,1TSIV@1239|Firmicutes,4HD8Y@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria ybbR GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - - - - - - - - - - YbbR NFINBLID_00489 904306.HMPREF9192_1521 2.68e-157 444.0 COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,4H9XZ@91061|Bacilli 91061|Bacilli S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria dacA GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 ko:K18672 - - - - ko00000,ko01000 - - - DisA_N NFINBLID_00490 1046629.Ssal_01349 0.0 864.0 COG0771@1|root,COG0771@2|Bacteria,1UHPI@1239|Firmicutes,4HVP0@91061|Bacilli 91061|Bacilli M Mur ligase, middle domain protein murE2 - 6.3.2.13 ko:K01928 ko00300,ko00550,map00300,map00550 - R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - DUF1727,Mur_ligase_M NFINBLID_00491 1046629.Ssal_01350 1.63e-189 526.0 COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,4HD1P@91061|Bacilli 91061|Bacilli S glutamine amidotransferase cobQ - - ko:K07009 - - - - ko00000 - - - GATase_3 NFINBLID_00492 1046629.Ssal_01351 0.0 1613.0 COG0392@1|root,COG2898@1|root,COG0392@2|Bacteria,COG2898@2|Bacteria,1TQI2@1239|Firmicutes,4HBHU@91061|Bacilli 91061|Bacilli J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms mprF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00726 - - ko00000,ko00001,ko00002,ko01000,ko01504 2.A.1.3.37 - iYO844.BG12900 DUF2156,LPG_synthase_TM NFINBLID_00493 1046629.Ssal_01352 9.04e-171 476.0 COG0596@1|root,COG0596@2|Bacteria,1V02M@1239|Firmicutes,4HN2K@91061|Bacilli 91061|Bacilli S Alpha beta hydrolase - - 1.11.1.10 ko:K00433 - - - - ko00000,ko01000 - - - Abhydrolase_1,Hydrolase_4 NFINBLID_00494 435842.HMPREF0848_00417 7.55e-53 166.0 COG4298@1|root,COG4298@2|Bacteria,1VCHF@1239|Firmicutes,4HMAW@91061|Bacilli 91061|Bacilli S yiaA/B two helix domain - - - - - - - - - - - - YiaAB NFINBLID_00495 435842.HMPREF0848_00416 0.0 1162.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4HBVV@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein ydiF - - ko:K06158 - - - - ko00000,ko03012 - - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn NFINBLID_00496 1046629.Ssal_01355 5.27e-147 414.0 COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,4HAVR@91061|Bacilli 91061|Bacilli F Cytidine monophosphokinase udk GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PRK NFINBLID_00497 1046629.Ssal_01356 2.06e-239 660.0 COG0513@1|root,COG0513@2|Bacteria,1TQ9R@1239|Firmicutes,4HANR@91061|Bacilli 91061|Bacilli L DEAD DEAH box helicase yfmL GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - - - - - - - - - - DEAD,Helicase_C NFINBLID_00498 1046629.Ssal_01357 8.16e-287 782.0 COG1181@1|root,COG1181@2|Bacteria,1UIK5@1239|Firmicutes,4HBFS@91061|Bacilli 91061|Bacilli M carbamoylphosphate synthase large subunit XK27_05680 - - - - - - - - - - - ATP-grasp_4,CPSase_L_D2 NFINBLID_00499 1046629.Ssal_01358 4.54e-197 543.0 COG4947@1|root,COG4947@2|Bacteria,1TSKW@1239|Firmicutes,4HB4B@91061|Bacilli 91061|Bacilli S Esterase XK27_05675 - - - - - - - - - - - Esterase NFINBLID_00500 1046629.Ssal_01359 8.48e-203 560.0 COG2819@1|root,COG2819@2|Bacteria,1UZZZ@1239|Firmicutes,4HCWE@91061|Bacilli 91061|Bacilli S Putative esterase XK27_05670 - - ko:K07017 - - - - ko00000 - - - Esterase NFINBLID_00501 1046629.Ssal_01360 0.0 918.0 COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,4H9MF@91061|Bacilli 91061|Bacilli C Belongs to the aldehyde dehydrogenase family gapN GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0043891,GO:0047100,GO:0055114 1.2.1.9 ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 M00308,M00633 R01058 RC00242 ko00000,ko00001,ko00002,ko01000 - - - Aldedh NFINBLID_00502 1046629.Ssal_01362 0.0 1098.0 COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,4H9VD@91061|Bacilli 91061|Bacilli G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) ptsI GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0051179,GO:0051234,GO:0071702 2.7.3.9 ko:K08483 ko02060,map02060 - - - ko00000,ko00001,ko01000,ko02000 8.A.7 - - PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C NFINBLID_00503 1046629.Ssal_01363 2.72e-51 162.0 COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,4HKGA@91061|Bacilli 91061|Bacilli G phosphocarrier protein Hpr ptsH GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - ko:K11189 - - - - ko00000,ko02000 4.A.2.1 - - PTS-HPr NFINBLID_00504 1046629.Ssal_01364 4.67e-279 763.0 COG0538@1|root,COG0538@2|Bacteria,1UHPE@1239|Firmicutes,4H9US@91061|Bacilli 91061|Bacilli C Isocitrate dehydrogenase icd - 1.1.1.42 ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 M00009,M00010,M00173,M00740 R00267,R00268,R01899 RC00001,RC00084,RC00114,RC00626,RC02801 br01601,ko00000,ko00001,ko00002,ko01000 - - - Iso_dh NFINBLID_00505 1046629.Ssal_01365 1.94e-267 732.0 COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,4H9YE@91061|Bacilli 91061|Bacilli C Belongs to the citrate synthase family citZ - 2.3.3.1 ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00740 R00351 RC00004,RC00067 br01601,ko00000,ko00001,ko00002,ko01000 - - - Citrate_synt NFINBLID_00506 1046629.Ssal_01366 0.0 1735.0 COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,4HB5N@91061|Bacilli 91061|Bacilli C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate acnA GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 M00009,M00010,M00012,M00173,M00740 R01324,R01325,R01900 RC00497,RC00498,RC00618 br01601,ko00000,ko00001,ko00002,ko01000 - - - Aconitase,Aconitase_C NFINBLID_00507 264199.stu1269 1.37e-45 147.0 COG0695@1|root,COG0695@2|Bacteria,1VEFX@1239|Firmicutes,4HNUX@91061|Bacilli 91061|Bacilli O Glutaredoxin nrdH - - ko:K06191 - - - - ko00000 - - - Glutaredoxin NFINBLID_00508 1046629.Ssal_01368 0.0 1430.0 COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,4H9X0@91061|Bacilli 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdE - 1.17.4.1 ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iYO844.BSU17380 RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN NFINBLID_00509 1046629.Ssal_01369 4.51e-236 648.0 COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,4H9WX@91061|Bacilli 91061|Bacilli F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides nrdF - 1.17.4.1 ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R02017,R02018,R02019,R02024 RC00613 ko00000,ko00001,ko00002,ko01000,ko03400 - - iSB619.SA_RS03915,iYO844.BSU17390 Ribonuc_red_sm NFINBLID_00510 1046629.Ssal_01371 0.0 1852.0 COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,4HAWB@91061|Bacilli 91061|Bacilli J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) ileS - 6.1.1.5 ko:K01870 ko00970,map00970 M00359,M00360 R03656 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1,zf-FPG_IleRS NFINBLID_00511 1046629.Ssal_01372 1.95e-191 533.0 COG3599@1|root,COG3599@2|Bacteria,1V27M@1239|Firmicutes,4HG80@91061|Bacilli 91061|Bacilli D Cell division initiation protein divIVA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K04074 - - - - ko00000,ko03036 - - - DivIVA NFINBLID_00512 1046629.Ssal_01373 1.79e-175 491.0 COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,4HD3F@91061|Bacilli 91061|Bacilli S conserved protein, contains S4-like domain ylmH - - - - - - - - - - - S4 NFINBLID_00513 435842.HMPREF0848_00397 1.95e-41 137.0 COG0762@1|root,COG0762@2|Bacteria 2|Bacteria D integral membrane protein yggT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02221 - - - - ko00000,ko02044 - - - YGGT NFINBLID_00514 1046629.Ssal_01374 1.19e-121 348.0 COG1799@1|root,COG1799@2|Bacteria 2|Bacteria D cell septum assembly sepF GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0032506,GO:0042802,GO:0044085,GO:0044464,GO:0051301,GO:0071840,GO:0071944,GO:0090529 - ko:K09772 - - - - ko00000,ko03036 - - - SepF NFINBLID_00515 1046629.Ssal_01375 1.05e-154 435.0 COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,4HC45@91061|Bacilli 91061|Bacilli S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis ylmE GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - ko:K06997 - - - - ko00000 - - - Ala_racemase_N NFINBLID_00516 1046629.Ssal_01376 1.4e-298 816.0 COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,4H9WZ@91061|Bacilli 91061|Bacilli D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity ftsZ GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03531 ko04112,map04112 - - - ko00000,ko00001,ko02048,ko03036,ko04812 - - - FtsZ_C,Tubulin NFINBLID_00517 904306.HMPREF9192_1193 4.25e-293 804.0 COG0849@1|root,COG0849@2|Bacteria,1TP1Z@1239|Firmicutes,4H9NF@91061|Bacilli 91061|Bacilli D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring ftsA GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0098552,GO:0098562 - ko:K03590 ko04112,map04112 - - - ko00000,ko00001,ko03036,ko04812 - - - DUF3484,FtsA,SHS2_FTSA NFINBLID_00518 904306.HMPREF9192_1192 4.47e-187 529.0 COG1589@1|root,COG1589@2|Bacteria,1VHEY@1239|Firmicutes 1239|Firmicutes D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex divIB - - ko:K03589 ko04112,map04112 - - - ko00000,ko00001,ko03036 - - - FtsQ,POTRA_1 NFINBLID_00519 1046629.Ssal_01379 1.01e-253 696.0 COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,4HBAQ@91061|Bacilli 91061|Bacilli M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) murG - 2.4.1.227 ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 - R05032,R05662 RC00005,RC00049 ko00000,ko00001,ko01000,ko01011 - GT28 - Glyco_tran_28_C,Glyco_transf_28 NFINBLID_00520 1046629.Ssal_01380 1.85e-316 863.0 COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,4HA5P@91061|Bacilli 91061|Bacilli M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) murD - 6.3.2.9 ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R02783 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M NFINBLID_00521 663952.SDD27957_07710 3.66e-12 63.5 2DJ77@1|root,304WT@2|Bacteria,1TXC0@1239|Firmicutes,4I69V@91061|Bacilli,1M9RX@119603|Streptococcus dysgalactiae group 91061|Bacilli S Protein of unknown function (DUF3165) - - - - - - - - - - - - DUF3165 NFINBLID_00522 1046629.Ssal_01382 0.0 1191.0 COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,4HAQ6@91061|Bacilli 91061|Bacilli T GTP-binding protein TypA typA - - ko:K06207 - - - - ko00000 - - - EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2 NFINBLID_00523 1046629.Ssal_01383 1.88e-225 622.0 COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,4HBAU@91061|Bacilli 91061|Bacilli G Glucokinase glcK GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0051156,GO:0071704,GO:1901135 2.7.1.2 ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 M00001,M00549 R00299,R01600,R01786 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS07790 ROK NFINBLID_00524 435842.HMPREF0848_00386 7.59e-37 124.0 COG4483@1|root,COG4483@2|Bacteria,1VK83@1239|Firmicutes,4HRG2@91061|Bacilli 91061|Bacilli S protein conserved in bacteria yqgQ - - - - - - - - - - - DUF910 NFINBLID_00525 1046629.Ssal_01385 2.33e-102 296.0 COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,4HHF8@91061|Bacilli 91061|Bacilli P Belongs to the Fur family perR - - ko:K03711,ko:K09825 - - - - ko00000,ko03000 - - - FUR NFINBLID_00526 1046629.Ssal_01386 8.39e-114 327.0 COG0783@1|root,COG0783@2|Bacteria,1VCVJ@1239|Firmicutes,4HMBD@91061|Bacilli 91061|Bacilli P Belongs to the Dps family dps - - ko:K04047 - - - - ko00000,ko03036 - - - Ferritin NFINBLID_00527 1046629.Ssal_01387 7.46e-130 371.0 COG1989@1|root,COG1989@2|Bacteria,1TQY4@1239|Firmicutes,4HCC3@91061|Bacilli 91061|Bacilli NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases comC - 3.4.23.43 ko:K02236,ko:K02654 - M00331,M00429 - - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 3.A.15.2 - - DiS_P_DiS,Peptidase_A24 NFINBLID_00528 322159.STER_0765 3.76e-228 640.0 COG2367@1|root,COG2367@2|Bacteria,1VHF8@1239|Firmicutes,4HU1N@91061|Bacilli 91061|Bacilli V D-alanyl-D-alanine carboxypeptidase - - - - - - - - - - - - Beta-lactamase2 NFINBLID_00529 1046629.Ssal_01389 9.19e-143 402.0 COG0605@1|root,COG0605@2|Bacteria,1TPXT@1239|Firmicutes,4HA6U@91061|Bacilli 91061|Bacilli C radicals which are normally produced within the cells and which are toxic to biological systems sodA GO:0005575,GO:0005576 1.15.1.1 ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 - - - ko00000,ko00001,ko01000 - - - Sod_Fe_C,Sod_Fe_N NFINBLID_00530 1046629.Ssal_01390 1.14e-234 647.0 COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,4HBB4@91061|Bacilli 91061|Bacilli L DNA polymerase III delta subunit holA - 2.7.7.7 ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta NFINBLID_00531 1046629.Ssal_01391 0.0 1811.0 COG2352@1|root,COG2352@2|Bacteria,1TQB6@1239|Firmicutes,4HCAF@91061|Bacilli 91061|Bacilli H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle ppc GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 M00168,M00170,M00171,M00172,M00173,M00346,M00374 R00345 RC02741 ko00000,ko00001,ko00002,ko01000 - - - PEPcase NFINBLID_00532 1046629.Ssal_01392 3.24e-84 249.0 2DNM7@1|root,32Y2X@2|Bacteria,1VF26@1239|Firmicutes,4HP82@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4430) - - - - - - - - - - - - DUF4430 NFINBLID_00533 1046629.Ssal_01394 4.98e-96 281.0 COG4720@1|root,COG4720@2|Bacteria,1V5GD@1239|Firmicutes,4HI8Y@91061|Bacilli 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - ko:K16927 - M00582 - - ko00000,ko00002,ko02000 3.A.1.32 - - ECF-ribofla_trS,ECF_trnsprt NFINBLID_00534 1046629.Ssal_01395 9.65e-163 456.0 COG1121@1|root,COG1121@2|Bacteria,1TQJ3@1239|Firmicutes,4HA2W@91061|Bacilli 91061|Bacilli P ABC transporter, ATP-binding protein sitB - 3.6.3.35 ko:K02074,ko:K09820,ko:K10830,ko:K11706,ko:K19973 ko02010,map02010 M00243,M00244,M00318,M00791,M00792 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.14,3.A.1.15.15,3.A.1.15.2,3.A.1.15.6 - - ABC_tran NFINBLID_00535 1046629.Ssal_01396 3.37e-170 478.0 COG1108@1|root,COG1108@2|Bacteria,1TPZB@1239|Firmicutes,4HBD7@91061|Bacilli 91061|Bacilli P ABC-type Mn2 Zn2 transport systems, permease components mtsC GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K11705,ko:K19972,ko:K19976 ko02010,map02010 M00318,M00791,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.14,3.A.1.15.15,3.A.1.15.2,3.A.1.15.6 - - ABC-3 NFINBLID_00536 1046629.Ssal_01397 1.13e-219 606.0 COG0803@1|root,COG0803@2|Bacteria,1TRKU@1239|Firmicutes,4HAKT@91061|Bacilli 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family psaA - - ko:K11704,ko:K19971,ko:K19975,ko:K19976 ko02010,map02010 M00318,M00791,M00792 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.14,3.A.1.15.15,3.A.1.15.2,3.A.1.15.6 - - ZnuA NFINBLID_00537 1046629.Ssal_01398 1.19e-145 411.0 COG1321@1|root,COG1321@2|Bacteria,1V4V7@1239|Firmicutes,4HHV4@91061|Bacilli 91061|Bacilli K iron dependent repressor sirR - - ko:K03709 - - - - ko00000,ko03000 - - - Fe_dep_repr_C,Fe_dep_repress,FeoA NFINBLID_00538 904306.HMPREF9192_1176 1.4e-188 526.0 COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,4HB11@91061|Bacilli 91061|Bacilli O Belongs to the peptidase M48B family htpX - - ko:K03799 - M00743 - - ko00000,ko00002,ko01000,ko01002 - - - Peptidase_M48 NFINBLID_00539 435842.HMPREF0848_00371 4.21e-118 339.0 COG1704@1|root,COG1704@2|Bacteria,1V1G7@1239|Firmicutes,4IR1J@91061|Bacilli 91061|Bacilli S LemA family lemA - - ko:K03744 - - - - ko00000 - - - LemA NFINBLID_00540 1046629.Ssal_01401 4.67e-234 644.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HK9Z@91061|Bacilli 91061|Bacilli F DNA RNA non-specific endonuclease spd - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 NFINBLID_00541 1046629.Ssal_01403 0.0 1439.0 COG5373@1|root,COG5434@1|root,COG5373@2|Bacteria,COG5434@2|Bacteria,1W0JP@1239|Firmicutes 1239|Firmicutes M Right handed beta helix region - - - - - - - - - - - - Beta_helix,Pectate_lyase_3 NFINBLID_00542 1046629.Ssal_01404 1.92e-185 518.0 COG5464@1|root,COG5464@2|Bacteria 2|Bacteria S double-stranded DNA endodeoxyribonuclease activity - - - - - - - - - - - - PDDEXK_2 NFINBLID_00543 264199.stu0711 0.0 1037.0 COG0286@1|root,COG0286@2|Bacteria,1TPGZ@1239|Firmicutes,4HA1J@91061|Bacilli 91061|Bacilli V type I restriction-modification system hsdM - 2.1.1.72 ko:K03427 - - - - ko00000,ko01000,ko02048 - - - HsdM_N,N6_Mtase NFINBLID_00544 1316408.HSISM1_1024 7.63e-58 179.0 COG3620@1|root,COG3620@2|Bacteria,1VD4K@1239|Firmicutes 1239|Firmicutes K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 NFINBLID_00545 936580.HMPREF1516_0491 6.28e-75 224.0 COG4679@1|root,COG4679@2|Bacteria,1VBJ4@1239|Firmicutes,4HQA2@91061|Bacilli 91061|Bacilli S Phage derived protein Gp49-like (DUF891) - - - - - - - - - - - - Gp49 NFINBLID_00546 1114972.AUAW01000025_gene777 1.61e-113 345.0 COG0732@1|root,COG0732@2|Bacteria,1TP5N@1239|Firmicutes,4HGJM@91061|Bacilli,3FB4X@33958|Lactobacillaceae 91061|Bacilli V Type I restriction modification DNA specificity domain - - 3.1.21.3 ko:K01154 - - - - ko00000,ko01000,ko02048 - - - Methylase_S NFINBLID_00547 888049.HMPREF8578_0412 5.16e-86 277.0 COG2114@1|root,COG2114@2|Bacteria,1VWRR@1239|Firmicutes 1239|Firmicutes T Pfam Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - - NFINBLID_00548 1123303.AQVD01000009_gene136 1.04e-47 157.0 COG2856@1|root,COG2856@2|Bacteria 2|Bacteria E Zn peptidase immA - - - - - - - - - - - Peptidase_M78 NFINBLID_00550 1046629.Ssal_01413 0.0 1933.0 COG0610@1|root,COG0610@2|Bacteria,1TP7S@1239|Firmicutes,4HB5A@91061|Bacilli 91061|Bacilli L Subunit R is required for both nuclease and ATPase activities, but not for modification hsdR - 3.1.21.3 ko:K01153 - - - - ko00000,ko01000,ko02048 - - - EcoR124_C,HSDR_N,ResIII NFINBLID_00551 1046629.Ssal_01414 8.11e-06 45.8 COG3620@1|root,COG3620@2|Bacteria,1VD4K@1239|Firmicutes 1239|Firmicutes K Helix-turn-helix domain - - - - - - - - - - - - HTH_3 NFINBLID_00552 904306.HMPREF9192_1161 1.27e-173 485.0 COG4221@1|root,COG4221@2|Bacteria,1V08N@1239|Firmicutes,4IPTJ@91061|Bacilli 91061|Bacilli S Belongs to the short-chain dehydrogenases reductases (SDR) family sdh - - - - - - - - - - - adh_short NFINBLID_00553 904306.HMPREF9192_1160 1.86e-250 690.0 COG1073@1|root,COG1073@2|Bacteria,1VEWD@1239|Firmicutes,4IQU0@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF2974) - - - - - - - - - - - - DUF2974 NFINBLID_00554 1046629.Ssal_01418 9.47e-144 405.0 COG2141@1|root,COG2141@2|Bacteria,1VJRB@1239|Firmicutes,4ISN7@91061|Bacilli 91061|Bacilli C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - - - - - - - - - - - NFINBLID_00555 1046629.Ssal_01419 1.91e-197 547.0 COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,4HDIH@91061|Bacilli 91061|Bacilli G hydrolase hmpP2 - - - - - - - - - - - Hydrolase_3 NFINBLID_00556 1123304.AQYA01000028_gene1720 2.15e-33 120.0 COG2461@1|root,COG2461@2|Bacteria 2|Bacteria P Hemerythrin HHE cation binding domain protein - - - - - - - - - - - - PAS_10 NFINBLID_00557 904306.HMPREF9192_1155 3.76e-192 536.0 COG3757@1|root,COG3757@2|Bacteria,1V2YH@1239|Firmicutes,4HI8U@91061|Bacilli 91061|Bacilli M Glycosyl hydrolase, family 25 - - 3.5.1.28 ko:K01447,ko:K07273 - - R04112 RC00064,RC00141 ko00000,ko01000 - - - Glyco_hydro_25 NFINBLID_00558 1046629.Ssal_01422 2.91e-104 301.0 COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,4HIH1@91061|Bacilli 91061|Bacilli S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - ko:K03976 - - - - ko00000,ko01000,ko03016 - - - tRNA_edit NFINBLID_00559 904306.HMPREF9192_1153 8.42e-149 419.0 COG0406@1|root,COG0406@2|Bacteria,1V7EZ@1239|Firmicutes,4HJCK@91061|Bacilli 91061|Bacilli G Phosphoglycerate mutase pgm - - - - - - - - - - - His_Phos_1 NFINBLID_00561 1046629.Ssal_01424 1.88e-223 615.0 COG1011@1|root,COG1011@2|Bacteria,1V5P7@1239|Firmicutes,4HHGY@91061|Bacilli 91061|Bacilli S hydrolase - - - ko:K07025 - - - - ko00000 - - - HAD_2 NFINBLID_00562 904293.HMPREF9176_0571 1.73e-36 130.0 2BXK6@1|root,33WGZ@2|Bacteria,1VVCA@1239|Firmicutes,4HWEI@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00563 1046629.Ssal_01428 1.08e-201 570.0 COG1388@1|root,COG1388@2|Bacteria 2|Bacteria M LysM domain - - - - - - - - - - - - LysM,Transglycosylas NFINBLID_00564 435842.HMPREF0848_00346 0.0 984.0 COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,4H9X4@91061|Bacilli 91061|Bacilli J Belongs to the class-II aminoacyl-tRNA synthetase family lysS - 6.1.1.6 ko:K04567 ko00970,map00970 M00359,M00360 R03658 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon NFINBLID_00566 888821.HMPREF9394_0792 6.79e-17 76.3 29RMD@1|root,30CQM@2|Bacteria,1UA84@1239|Firmicutes,4IKJF@91061|Bacilli,1WRWU@1305|Streptococcus sanguinis 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00567 1046629.Ssal_01431 2.99e-291 798.0 COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,4HAEA@91061|Bacilli 91061|Bacilli P H( )-stimulated, divalent metal cation uptake system mntH - - ko:K03322 - - - - ko00000,ko02000 2.A.55.2.6,2.A.55.3 - - Nramp NFINBLID_00568 264199.stu0676 2.97e-45 145.0 COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes,4HNSP@91061|Bacilli 91061|Bacilli S protein conserved in bacteria XK27_12190 - - - - - - - - - - - PC4 NFINBLID_00570 904306.HMPREF9192_1141 2.1e-110 319.0 COG1268@1|root,COG1268@2|Bacteria,1VA1G@1239|Firmicutes,4HNE8@91061|Bacilli 91061|Bacilli S biotin synthase bioY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03523 ko02010,map02010 M00581,M00582 - - ko00000,ko00001,ko00002,ko02000 2.A.88.1,2.A.88.2 - - BioY NFINBLID_00571 904306.HMPREF9192_1140 0.0 872.0 COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,4HBEG@91061|Bacilli 91061|Bacilli O Peptidase U32 yrrO - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32,Peptidase_U32_C NFINBLID_00572 1046629.Ssal_01437 4.13e-227 625.0 COG0826@1|root,COG0826@2|Bacteria,1TQIZ@1239|Firmicutes,4HA2T@91061|Bacilli 91061|Bacilli O Peptidase U32 yrrN - - ko:K08303 ko05120,map05120 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_U32 NFINBLID_00574 1046629.Ssal_01439 6.48e-89 262.0 COG4980@1|root,COG4980@2|Bacteria,1VFY7@1239|Firmicutes,4HNWV@91061|Bacilli 91061|Bacilli S General stress protein ytxH - - - - - - - - - - - YtxH NFINBLID_00575 904306.HMPREF9192_1133 9.98e-28 106.0 COG4768@1|root,COG4768@2|Bacteria,1VAXN@1239|Firmicutes,4HM93@91061|Bacilli 91061|Bacilli S protein containing a divergent version of the methyl-accepting chemotaxis-like domain ytxG - - - - - - - - - - - DUF948 NFINBLID_00576 1046629.Ssal_01442 2.14e-190 528.0 COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,4HAT0@91061|Bacilli 91061|Bacilli M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins lgt - - ko:K13292 - - - - ko00000,ko01000 - - - LGT NFINBLID_00577 1046629.Ssal_01443 1.12e-215 596.0 COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,4HAXR@91061|Bacilli 91061|Bacilli F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion hprK GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K06023 - - - - ko00000,ko01000 - - - Hpr_kinase_C,Hpr_kinase_N NFINBLID_00578 1046629.Ssal_01444 1.45e-55 173.0 COG1983@1|root,COG1983@2|Bacteria,1VF0M@1239|Firmicutes,4IRAN@91061|Bacilli 91061|Bacilli KT PspC domain WQ51_05770 - - - - - - - - - - - PspC NFINBLID_00579 1046629.Ssal_01446 0.0 1335.0 COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,4HAGY@91061|Bacilli 91061|Bacilli K Transcriptional accessory protein tex - - ko:K06959 - - - - ko00000 - - - HHH_3,S1,Tex_N,Tex_YqgF NFINBLID_00581 1046629.Ssal_01448 2.79e-200 556.0 COG0701@1|root,COG0701@2|Bacteria,1TQHK@1239|Firmicutes,4HB25@91061|Bacilli 91061|Bacilli S permease XK27_03015 - - ko:K07089 - - - - ko00000 - - - ArsP_1 NFINBLID_00582 904306.HMPREF9192_1125 4.15e-192 533.0 COG3689@1|root,COG3689@2|Bacteria,1V3EX@1239|Firmicutes,4HGMG@91061|Bacilli 91061|Bacilli S TIGR03943 family XK27_03010 - - ko:K08986 - - - - ko00000 - - - DUF1980 NFINBLID_00583 1046629.Ssal_01450 0.0 998.0 COG0659@1|root,COG0659@2|Bacteria,1TPI4@1239|Firmicutes,4H9V4@91061|Bacilli 91061|Bacilli P Sulfate permease and related transporters (MFS superfamily) yvdB GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008272,GO:0008509,GO:0008514,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:0098660,GO:0098661,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039 - ko:K03321 - - - - ko00000,ko02000 2.A.53.3 - - STAS,Sulfate_transp NFINBLID_00584 1046629.Ssal_01451 1.28e-130 372.0 2F636@1|root,33YMH@2|Bacteria,1VYAW@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - NFINBLID_00585 1046629.Ssal_01453 2.14e-147 415.0 COG2755@1|root,COG2755@2|Bacteria,1V1CQ@1239|Firmicutes,4HGVZ@91061|Bacilli 91061|Bacilli E GDSL-like Lipase/Acylhydrolase - - - - - - - - - - - - Lipase_GDSL_2 NFINBLID_00586 1046629.Ssal_01454 8.22e-122 350.0 COG1266@1|root,COG1266@2|Bacteria,1VBYM@1239|Firmicutes,4HM2K@91061|Bacilli 91061|Bacilli S CAAX protease self-immunity - - - - - - - - - - - - Abi NFINBLID_00587 1046629.Ssal_01455 7.23e-66 201.0 2FBVV@1|root,3440F@2|Bacteria,1VZAT@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - NFINBLID_00589 1046629.Ssal_01457 4.1e-84 248.0 2AK1X@1|root,31ARI@2|Bacteria,1V717@1239|Firmicutes,4HIQ9@91061|Bacilli 91061|Bacilli S Pyrimidine dimer DNA glycosylase yqeB - - - - - - - - - - - Pyr_excise NFINBLID_00590 435842.HMPREF0848_00317 6.56e-79 235.0 COG3272@1|root,COG3272@2|Bacteria,1VGGK@1239|Firmicutes,4HP7S@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1722) - - - - - - - - - - - - DUF1722 NFINBLID_00591 1005705.HMPREF9967_0252 2.89e-28 108.0 2DIXF@1|root,304BM@2|Bacteria,1TWG1@1239|Firmicutes,4I59C@91061|Bacilli,43G59@68892|Streptococcus infantis 91061|Bacilli M Bacterial lipoprotein - - - - - - - - - - - - DUF3642 NFINBLID_00593 1046629.Ssal_01461 5.28e-159 447.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - - - - - - - - - - Abi NFINBLID_00594 1046629.Ssal_01462 1.61e-64 197.0 2CUT8@1|root,32SW2@2|Bacteria,1VAQK@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - NFINBLID_00595 1123300.AUIN01000009_gene228 6.21e-96 283.0 COG1309@1|root,COG1309@2|Bacteria,1VCGN@1239|Firmicutes,4HMEM@91061|Bacilli 91061|Bacilli K TetR family transcriptional regulator - - - - - - - - - - - - TetR_N NFINBLID_00596 1316408.HSISM1_1770 4.87e-106 309.0 COG0500@1|root,COG0500@2|Bacteria,1UI83@1239|Firmicutes,4HHCN@91061|Bacilli 91061|Bacilli Q Methyltransferase domain - - - - - - - - - - - - Methyltransf_11,Methyltransf_25 NFINBLID_00597 1046629.Ssal_01463 8.71e-159 445.0 COG2819@1|root,COG2819@2|Bacteria,1V2YF@1239|Firmicutes,4IQ46@91061|Bacilli 91061|Bacilli S Putative esterase - - - - - - - - - - - - Esterase NFINBLID_00598 435842.HMPREF0848_00311 6.08e-230 634.0 COG0614@1|root,COG0614@2|Bacteria,1TSDG@1239|Firmicutes,4HDG3@91061|Bacilli 91061|Bacilli P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component fatB - - ko:K02016 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - Peripla_BP_2 NFINBLID_00599 435842.HMPREF0848_00310 2.77e-171 479.0 COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,4HETN@91061|Bacilli 91061|Bacilli HP ABC transporter fecE - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran NFINBLID_00600 435842.HMPREF0848_00309 1.43e-217 604.0 COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,4HAUK@91061|Bacilli 91061|Bacilli P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily fecD - - ko:K02015 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko02000 3.A.1.14 - - FecCD NFINBLID_00601 435842.HMPREF0848_00308 4.45e-153 432.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - - - - - - - - - - Abi NFINBLID_00602 435842.HMPREF0848_00305 1.33e-192 535.0 28KEH@1|root,2ZA0R@2|Bacteria 2|Bacteria S Domain of unknown function (DUF4300) - - - - - - - - - - - - DUF4300 NFINBLID_00603 1046629.Ssal_01469 1.33e-118 340.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator tetR - - - - - - - - - - - TetR_C_8,TetR_N NFINBLID_00604 1046629.Ssal_01470 0.0 1031.0 COG0477@1|root,COG2211@1|root,COG0477@2|Bacteria,COG2211@2|Bacteria,1TPHW@1239|Firmicutes,4H9YA@91061|Bacilli 91061|Bacilli P Major facilitator superfamily - - - - - - - - - - - - MFS_1 NFINBLID_00605 1127131.WEISSC39_08120 5.78e-16 77.8 2DMBI@1|root,32H42@2|Bacteria,1VFT3@1239|Firmicutes,4HK1A@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4767) yjdB - - - - - - - - - - - DUF4767 NFINBLID_00608 1046629.Ssal_01475 2.69e-140 397.0 COG3142@1|root,COG3142@2|Bacteria,1V3V5@1239|Firmicutes,4HCVQ@91061|Bacilli 91061|Bacilli P Participates in the control of copper homeostasis cutC - - ko:K06201 - - - - ko00000 - - - CutC NFINBLID_00609 888833.HMPREF9421_1585 1.56e-161 456.0 COG1266@1|root,COG1266@2|Bacteria,1V1I8@1239|Firmicutes 1239|Firmicutes S CAAX amino terminal protease family - - - ko:K07052 - - - - ko00000 - - - Abi NFINBLID_00610 435842.HMPREF0848_00302 5.77e-127 362.0 COG1418@1|root,COG1418@2|Bacteria,1V7IZ@1239|Firmicutes,4HIVB@91061|Bacilli 91061|Bacilli F HD superfamily hydrolase yagB - - ko:K06950 - - - - ko00000 - - - HD NFINBLID_00611 1046629.Ssal_01477 1.91e-123 353.0 COG1309@1|root,COG1309@2|Bacteria,1VGCX@1239|Firmicutes,4HRBM@91061|Bacilli 91061|Bacilli K Bacterial regulatory proteins, tetR family - - - - - - - - - - - - TetR_N NFINBLID_00612 904306.HMPREF9192_1447 5.62e-190 528.0 COG1307@1|root,COG1307@2|Bacteria,1V229@1239|Firmicutes,4IPK5@91061|Bacilli 91061|Bacilli S EDD domain protein, DegV family ChZ00x2 - - - - - - - - - - - DegV NFINBLID_00613 904306.HMPREF9192_1446 2.11e-254 701.0 COG2807@1|root,COG2807@2|Bacteria,1TP9R@1239|Firmicutes,4H9YZ@91061|Bacilli 91061|Bacilli P transporter yycB - - ko:K03449 - - - - ko00000,ko02000 2.A.1.17 - - MFS_1 NFINBLID_00614 1316408.HSISM1_1088 3.24e-167 468.0 COG4221@1|root,COG4221@2|Bacteria,1V0BE@1239|Firmicutes,4HDZJ@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4336) - - - - - - - - - - - - DUF4336 NFINBLID_00615 1316408.HSISM1_1087 3.58e-166 466.0 COG0596@1|root,COG0596@2|Bacteria,1UMWY@1239|Firmicutes,4HCGN@91061|Bacilli 91061|Bacilli S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - - - - - - - - - - Abhydrolase_1,Abhydrolase_6,Hydrolase_4 NFINBLID_00617 435842.HMPREF0848_00286 0.0 1316.0 COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,4H9SP@91061|Bacilli 91061|Bacilli P COG2217 Cation transport ATPase cadA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.3,3.6.3.5 ko:K01534 - - - - ko00000,ko01000 3.A.3.6 - - E1-E2_ATPase,HMA,Hydrolase NFINBLID_00618 435842.HMPREF0848_00285 4.62e-81 240.0 COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,4HKYT@91061|Bacilli 91061|Bacilli K Transcriptional regulator - - - ko:K21903 - - - - ko00000,ko03000 - - - HTH_20,HTH_5 NFINBLID_00619 435842.HMPREF0848_00284 3.59e-69 209.0 COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,4HB3R@91061|Bacilli 91061|Bacilli P Mediates zinc uptake. May also transport other divalent cations XK27_05385 - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip NFINBLID_00620 435842.HMPREF0848_00283 1.39e-101 295.0 COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,4HB3R@91061|Bacilli 91061|Bacilli P Mediates zinc uptake. May also transport other divalent cations zupT - - ko:K07238 - - - - ko00000,ko02000 2.A.5.5 - - Zip NFINBLID_00621 1054460.SPPN_01620 8.46e-50 158.0 COG0389@1|root,COG0389@2|Bacteria 2|Bacteria L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII uvrX - 2.7.7.7 ko:K02346,ko:K03502,ko:K14161 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH NFINBLID_00622 562983.HMPREF0433_01099 4.1e-73 219.0 2DVQU@1|root,33WU0@2|Bacteria,1VW5E@1239|Firmicutes,4HWDN@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00623 1054460.SPPN_01630 7.32e-79 234.0 2E59Z@1|root,33028@2|Bacteria,1VFMU@1239|Firmicutes,4HPP8@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00624 1054460.SPPN_01635 8.78e-67 202.0 2E660@1|root,330UP@2|Bacteria,1VFJD@1239|Firmicutes,4HPUS@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00625 1203590.HMPREF1481_00525 0.0 934.0 COG0488@1|root,COG0488@2|Bacteria,1TQNA@1239|Firmicutes,4H9VW@91061|Bacilli 91061|Bacilli S ATPase components of ABC transporters with duplicated ATPase domains yheS_2 - - ko:K18231 ko02010,map02010 - - - br01600,ko00000,ko00001,ko01504,ko02000 3.A.1.121.1,3.A.1.121.3 - - ABC_tran,ABC_tran_Xtn NFINBLID_00626 1008453.HMPREF9957_0964 1.55e-275 755.0 COG0477@1|root,COG0477@2|Bacteria,1UHRM@1239|Firmicutes,4ISTP@91061|Bacilli,2TQ4E@28037|Streptococcus mitis 91061|Bacilli EGP Transmembrane secretion effector - - - ko:K08217 - - - - br01600,ko00000,ko01504,ko02000 2.A.1.21.1,2.A.1.21.22 - - MFS_1 NFINBLID_00627 1008453.HMPREF9957_0963 3.6e-31 109.0 29NGK@1|root,309EI@2|Bacteria,1U4XK@1239|Firmicutes,4IENZ@91061|Bacilli,2TQDT@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00628 435842.HMPREF0848_00282 0.0 883.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA - 2.1.1.190 ko:K03215 - - - - ko00000,ko01000,ko03009 - - - TRAM,tRNA_U5-meth_tr NFINBLID_00629 1046629.Ssal_01496 1.28e-126 360.0 COG2128@1|root,COG2128@2|Bacteria 2|Bacteria S hydroperoxide reductase activity mip - - - - - - - - - - - CMD NFINBLID_00630 1046629.Ssal_01497 1.5e-254 698.0 COG1960@1|root,COG1960@2|Bacteria,1UYHK@1239|Firmicutes,4HCT5@91061|Bacilli 91061|Bacilli I acyl-CoA dehydrogenase - - - - - - - - - - - - Acyl-CoA_dh_N NFINBLID_00631 904306.HMPREF9192_1383 8.07e-183 513.0 COG1275@1|root,COG1275@2|Bacteria,1UYTE@1239|Firmicutes,4HGBI@91061|Bacilli 91061|Bacilli P C4-dicarboxylate transporter malic acid transport ydiA - - ko:K11041 ko05150,map05150 - - - ko00000,ko00001,ko02042 2.A.16 - - SLAC1 NFINBLID_00632 904306.HMPREF9192_1382 0.0 877.0 COG1316@1|root,COG1316@2|Bacteria,1TSWQ@1239|Firmicutes,4HE66@91061|Bacilli 91061|Bacilli K Transcriptional regulator msrR - - - - - - - - - - - LytR_cpsA_psr NFINBLID_00633 1046629.Ssal_01508 2.42e-197 546.0 COG0077@1|root,COG0077@2|Bacteria,1TPDN@1239|Firmicutes,4HA96@91061|Bacilli 91061|Bacilli E Prephenate dehydratase pheA GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51 ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00024 R00691,R01373 RC00360 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU27900 ACT,PDT NFINBLID_00634 904306.HMPREF9192_1380 8.92e-111 318.0 COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,4HKD6@91061|Bacilli 91061|Bacilli F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate aroK GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02412 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - SKI NFINBLID_00635 1046629.Ssal_01510 1.39e-296 810.0 COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,4HBHZ@91061|Bacilli 91061|Bacilli E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate aroA GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03460 RC00350 ko00000,ko00001,ko00002,ko01000 - - - EPSP_synthase NFINBLID_00636 904306.HMPREF9192_1378 6.02e-219 605.0 COG0039@1|root,COG0039@2|Bacteria,1UXY2@1239|Firmicutes,4HD1S@91061|Bacilli 91061|Bacilli C Belongs to the LDH MDH superfamily hicD2 - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N NFINBLID_00637 1046629.Ssal_01512 2.99e-71 214.0 COG3679@1|root,COG3679@2|Bacteria,1VASS@1239|Firmicutes,4HPJM@91061|Bacilli 91061|Bacilli S Belongs to the UPF0342 family XK26_04240 - - - - - - - - - - - Com_YlbF NFINBLID_00638 904306.HMPREF9192_1376 9.54e-265 725.0 COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,4HBI4@91061|Bacilli 91061|Bacilli E prephenate dehydrogenase tyrA GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12 ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 M00025 R01728 RC00125 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22610 ACT,PDH NFINBLID_00639 904306.HMPREF9192_1375 1.83e-279 764.0 COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,4HA0H@91061|Bacilli 91061|Bacilli E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system aroC GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R01714 RC00586 ko00000,ko00001,ko00002,ko01000 - - - Chorismate_synt NFINBLID_00640 904306.HMPREF9192_1374 6.14e-259 709.0 COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,4HAKN@91061|Bacilli 91061|Bacilli E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) aroB - 4.2.3.4 ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03083 RC00847 ko00000,ko00001,ko00002,ko01000 - - - DHQ_synthase NFINBLID_00641 904306.HMPREF9192_1373 1.41e-206 571.0 COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,4HD4R@91061|Bacilli 91061|Bacilli E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) aroE GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R02413 RC00206 ko00000,ko00001,ko00002,ko01000 - - - Shikimate_dh_N NFINBLID_00642 904306.HMPREF9192_1372 1.74e-152 429.0 COG0710@1|root,COG0710@2|Bacteria,1VHVX@1239|Firmicutes,4IPJP@91061|Bacilli 91061|Bacilli E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate aroD - 4.2.1.10 ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00022 R03084 RC00848 ko00000,ko00001,ko00002,ko01000 - - - DHquinase_I NFINBLID_00643 1046629.Ssal_01518 3.82e-276 755.0 COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,4HAA1@91061|Bacilli 91061|Bacilli J Methyltransferase ywbD - 2.1.1.191 ko:K06969 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_SAM NFINBLID_00644 1046629.Ssal_01519 0.0 1389.0 COG1368@1|root,COG1368@2|Bacteria,1TRMA@1239|Firmicutes,4H9S0@91061|Bacilli 91061|Bacilli M Belongs to the LTA synthase family ltaS GO:0005575,GO:0005576 2.7.8.20 ko:K19005 ko00561,ko01100,map00561,map01100 - R05081,R10849 RC00017 ko00000,ko00001,ko01000 - - - Sulfatase NFINBLID_00645 1046629.Ssal_01520 1.1e-34 118.0 2FKS5@1|root,34CCP@2|Bacteria,1W67C@1239|Firmicutes 1239|Firmicutes - - WQ51_00785 - - - - - - - - - - - - NFINBLID_00646 764291.STRUR_0112 7.3e-14 68.6 2EGA8@1|root,33A22@2|Bacteria,1VM18@1239|Firmicutes,4HRTB@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00648 372457.A7DYC5_9CAUD 7.6e-97 299.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - NFINBLID_00652 888049.HMPREF8578_0250 1.48e-32 114.0 COG5546@1|root,COG5546@2|Bacteria,1VGGV@1239|Firmicutes,4HPNN@91061|Bacilli 91061|Bacilli S COG5546 Small integral membrane protein hol - - - - - - - - - - - Phage_holin_1 NFINBLID_00653 1051631.F8HGP0_9CAUD 4.83e-70 214.0 4QBDC@10239|Viruses,4QVEM@35237|dsDNA viruses no RNA stage,4QQ6A@28883|Caudovirales 28883|Caudovirales S Pfam:Phage_holin_4_1 - GO:0005575,GO:0018995,GO:0033643,GO:0033644,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279 - - - - - - - - - - - NFINBLID_00655 90410.Q9XJB2_9CAUD 1.27e-215 626.0 4QMQJ@10699|Siphoviridae 10699|Siphoviridae - - - - - - - - - - - - - - - NFINBLID_00656 1051631.F8HGN7_9CAUD 0.0 1266.0 4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - - - - - - - - - - - - - NFINBLID_00657 90410.Q9XJB0_9CAUD 8.37e-285 788.0 4QBF8@10239|Viruses,4QUS7@35237|dsDNA viruses no RNA stage,4QPI9@28883|Caudovirales,4QKN2@10699|Siphoviridae 10699|Siphoviridae S Phage tail protein - - - - - - - - - - - - - NFINBLID_00658 64186.O64282_9CAUD 0.0 2044.0 4QAK6@10239|Viruses,4QUP9@35237|dsDNA viruses no RNA stage,4QPBY@28883|Caudovirales,4QKKV@10699|Siphoviridae 10699|Siphoviridae S peptidoglycan catabolic process - GO:0008150,GO:0016032,GO:0019058,GO:0019068,GO:0044403,GO:0044419,GO:0051704,GO:0098003 - - - - - - - - - - - NFINBLID_00660 1051631.F8HGT6_9CAUD 1.12e-122 352.0 4QAYN@10239|Viruses,4QUR7@35237|dsDNA viruses no RNA stage,4QPCU@28883|Caudovirales,4QKPS@10699|Siphoviridae 10699|Siphoviridae S Pfam:Phage_TTP_1 - - - - - - - - - - - - - NFINBLID_00661 90410.Q9XJA5_9CAUD 1.03e-74 224.0 4QAVH@10239|Viruses,4QX2F@35237|dsDNA viruses no RNA stage,4QR7A@28883|Caudovirales,4QM2J@10699|Siphoviridae 10699|Siphoviridae S Protein of unknown function (DUF806) - - - - - - - - - - - - - NFINBLID_00662 112023.Q9MCK1_9CAUD 1.89e-85 253.0 4QB1F@10239|Viruses,4QUYH@35237|dsDNA viruses no RNA stage,4QPSW@28883|Caudovirales,4QKPW@10699|Siphoviridae 10699|Siphoviridae S exonuclease activity - - - - - - - - - - - - - NFINBLID_00663 1051631.F8HGT3_9CAUD 1.7e-81 241.0 4QB12@10239|Viruses,4QV5M@35237|dsDNA viruses no RNA stage,4QPN3@28883|Caudovirales,4QKV7@10699|Siphoviridae 10699|Siphoviridae S Phage head-tail joining protein - - - - - - - - - - - - - NFINBLID_00664 1051631.F8HGT2_9CAUD 1.13e-60 187.0 4QBCW@10239|Viruses,4QUN6@35237|dsDNA viruses no RNA stage,4QPS7@28883|Caudovirales,4QKNA@10699|Siphoviridae 10699|Siphoviridae S Phage gp6-like head-tail connector protein - - - - - - - - - - - - - NFINBLID_00665 64186.Q9XJ79_9CAUD 1.39e-260 717.0 4QAK6@10239|Viruses,4QPBY@28883|Caudovirales,4QKP8@10699|Siphoviridae 10699|Siphoviridae S peptidase activity - GO:0005575,GO:0019012,GO:0044423,GO:0098015,GO:0098026 - - - - - - - - - - - NFINBLID_00666 1051631.F8HGT0_9CAUD 1.55e-149 421.0 4QBNM@10239|Viruses,4QUT2@35237|dsDNA viruses no RNA stage,4QPUI@28883|Caudovirales,4QKV6@10699|Siphoviridae 10699|Siphoviridae S Clp protease - - - - - - - - - - - - - NFINBLID_00667 112023.Q9MCK6_9CAUD 8.31e-255 701.0 4QAYV@10239|Viruses,4QUZ7@35237|dsDNA viruses no RNA stage,4QPU3@28883|Caudovirales,4QKKX@10699|Siphoviridae 10699|Siphoviridae S Phage portal protein - - - - - - - - - - - - - NFINBLID_00669 764291.STRUR_0826 0.0 1105.0 COG4626@1|root,COG4626@2|Bacteria,1TR5W@1239|Firmicutes,4HEDC@91061|Bacilli 91061|Bacilli S Phage terminase-like protein, large subunit - - - - - - - - - - - - Terminase_1 NFINBLID_00670 112023.Q9MCK9_9CAUD 9.73e-84 249.0 4QBS6@10239|Viruses,4QUNW@35237|dsDNA viruses no RNA stage,4QPP2@28883|Caudovirales,4QM0S@10699|Siphoviridae 10699|Siphoviridae S Phage terminase, small subunit - - - - - - - - - - - - - NFINBLID_00675 306323.Q56S64_9CAUD 1.33e-57 184.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding - - - - - - - - - - - - - NFINBLID_00676 1005705.HMPREF9967_1027 5.06e-31 117.0 29RF0@1|root,30CHJ@2|Bacteria,1TWNK@1239|Firmicutes,4I5GF@91061|Bacilli,43GMX@68892|Streptococcus infantis 91061|Bacilli S Protein of unknown function (DUF1642) - - - - - - - - - - - - DUF1642 NFINBLID_00680 112023.Q9MCM0_9CAUD 5.25e-96 280.0 4QW7S@35237|dsDNA viruses no RNA stage,4QPK3@28883|Caudovirales,4QKQC@10699|Siphoviridae 10699|Siphoviridae S magnesium ion binding - - - - - - - - - - - - - NFINBLID_00681 646413.C5IUI2_9CAUD 5.51e-83 248.0 4QAU9@10239|Viruses,4QVR2@35237|dsDNA viruses no RNA stage,4QQV4@28883|Caudovirales,4QKUJ@10699|Siphoviridae 10699|Siphoviridae S Single-strand binding protein family - - - - - - - - - - - - - NFINBLID_00682 1035189.HMPREF9954_0291 7.6e-127 374.0 2AN0F@1|root,31CXP@2|Bacteria,1UQF0@1239|Firmicutes,4HXEW@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1351) - - - - - - - - - - - - DUF1351 NFINBLID_00683 1289598.M1PFN1_9CAUD 7.71e-136 390.0 4QBHS@10239|Viruses,4QUVV@35237|dsDNA viruses no RNA stage,4QPT9@28883|Caudovirales 28883|Caudovirales S DNA metabolic process - - - - - - - - - - - - - NFINBLID_00685 73422.L0P359_9CAUD 3.34e-172 482.0 4QBU2@10239|Viruses,4QV13@35237|dsDNA viruses no RNA stage,4QPH3@28883|Caudovirales,4QM65@10699|Siphoviridae 10699|Siphoviridae S IstB-like ATP binding protein - - - - - - - - - - - - - NFINBLID_00686 1123299.AUKZ01000018_gene209 2.31e-61 199.0 COG3935@1|root,COG3935@2|Bacteria,1UJ33@1239|Firmicutes,4HKZC@91061|Bacilli 91061|Bacilli L Replication initiation and membrane attachment - - - ko:K02086 - - - - ko00000 - - - DnaB_2,HTH_36 NFINBLID_00688 435842.HMPREF0848_00198 1.39e-91 311.0 COG4932@1|root,COG4932@2|Bacteria,1UXB4@1239|Firmicutes 1239|Firmicutes M Pilin isopeptide linkage domain protein - - - - - - - - - - - - Cna_B,Collagen_bind,FctA,Gram_pos_anchor,VWA,YSIRK_signal NFINBLID_00691 1069533.Sinf_0769 2.68e-34 119.0 2ENNN@1|root,33GA0@2|Bacteria,1VN2K@1239|Firmicutes,4HR9I@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00692 1029718.SFBM_1169 2.6e-94 284.0 COG3617@1|root,COG3645@1|root,COG3617@2|Bacteria,COG3645@2|Bacteria,1TPKA@1239|Firmicutes,24BSZ@186801|Clostridia,36EAE@31979|Clostridiaceae 186801|Clostridia K Phage antirepressor protein - - - ko:K07741 - - - - ko00000 - - - ANT,Bro-N NFINBLID_00695 157924.Q7Y4M0_9CAUD 5.61e-58 181.0 4QAQV@10239|Viruses,4QUPK@35237|dsDNA viruses no RNA stage,4QPCB@28883|Caudovirales,4QKM5@10699|Siphoviridae 10699|Siphoviridae S sequence-specific DNA binding - GO:0001047,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010944,GO:0016032,GO:0019012,GO:0019042,GO:0019044,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043900,GO:0043902,GO:0043903,GO:0044212,GO:0044403,GO:0044419,GO:0045892,GO:0045934,GO:0046782,GO:0048518,GO:0048519,GO:0048523,GO:0048524,GO:0050434,GO:0050789,GO:0050792,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051704,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - - - - - - - - - - - NFINBLID_00699 646413.C5IUL7_9CAUD 3.44e-264 725.0 4QAQE@10239|Viruses,4QUYF@35237|dsDNA viruses no RNA stage,4QPDM@28883|Caudovirales,4QKN9@10699|Siphoviridae 10699|Siphoviridae S Phage integrase family - GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015074,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - - - - - - - - - - - NFINBLID_00700 1046629.Ssal_01521 6.13e-315 857.0 COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,4HAKI@91061|Bacilli 91061|Bacilli G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis eno GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 M00001,M00002,M00003,M00346,M00394 R00658 RC00349 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 - - - Enolase_C,Enolase_N NFINBLID_00701 1046629.Ssal_01522 6.68e-98 285.0 COG5506@1|root,COG5506@2|Bacteria,1VFCV@1239|Firmicutes,4HNNE@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1694) XK27_05190 - - - - - - - - - - - DUF1694 NFINBLID_00702 1046629.Ssal_01524 6.56e-253 695.0 COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes 1239|Firmicutes G Belongs to the glycerate kinase type-1 family glxK - 2.7.1.165 ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 - R08572 RC00002,RC00428 ko00000,ko00001,ko01000 - - - Gly_kinase NFINBLID_00703 1046629.Ssal_01525 6.59e-254 696.0 COG2315@1|root,COG2315@2|Bacteria,1V4K7@1239|Firmicutes,4HP2K@91061|Bacilli 91061|Bacilli S YjbR XK27_07735 - - - - - - - - - - - EVE,YjbR NFINBLID_00704 1046629.Ssal_01526 6.39e-234 644.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,4H9NG@91061|Bacilli 91061|Bacilli K Catabolite control protein A ccpA GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 NFINBLID_00705 1046629.Ssal_01528 1.04e-246 679.0 COG0006@1|root,COG0006@2|Bacteria,1TQ6R@1239|Firmicutes,4HA5I@91061|Bacilli 91061|Bacilli E Belongs to the peptidase M24B family pepQ - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 NFINBLID_00706 1046629.Ssal_01529 1.17e-84 249.0 COG1098@1|root,COG1098@2|Bacteria,1VASQ@1239|Firmicutes,4HKSW@91061|Bacilli 91061|Bacilli J RNA binding protein, contains ribosomal protein S1 domain yugI - - ko:K07570 - - - - ko00000 - - - S1 NFINBLID_00707 1046629.Ssal_01530 0.0 941.0 COG0561@1|root,COG0652@1|root,COG0561@2|Bacteria,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,4H9V0@91061|Bacilli 91061|Bacilli G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiB - 5.2.1.8 ko:K03768 - - - - ko00000,ko01000,ko03110 - - - Hydrolase_3,Pro_isomerase NFINBLID_00708 1046629.Ssal_01531 5.69e-105 303.0 COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,4HGZX@91061|Bacilli 91061|Bacilli O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA smpB GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - ko:K03664 - - - - ko00000 - - - SmpB NFINBLID_00709 1046629.Ssal_01532 0.0 1569.0 COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,4HBBH@91061|Bacilli 91061|Bacilli J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs rnr - - ko:K12573 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03016,ko03019 - - - OB_RNB,RNB,S1 NFINBLID_00710 904306.HMPREF9192_1354 1.06e-44 145.0 COG1314@1|root,COG1314@2|Bacteria,1VEQR@1239|Firmicutes,4HNKC@91061|Bacilli 91061|Bacilli U Preprotein translocase subunit SecG secG GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944 - ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecG NFINBLID_00711 1046629.Ssal_01534 3.58e-282 772.0 COG0477@1|root,COG2814@2|Bacteria,1TRDJ@1239|Firmicutes,4H9Q9@91061|Bacilli 91061|Bacilli EGP Major Facilitator pmrA - - ko:K08161 - - - - ko00000,ko02000 2.A.1.2.20 - - MFS_1,MFS_1_like,Sugar_tr NFINBLID_00712 1046629.Ssal_01535 3.19e-132 375.0 COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,4HII3@91061|Bacilli 91061|Bacilli H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A coaE GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 ko:K00859 ko00770,ko01100,map00770,map01100 M00120 R00130 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08510 CoaE NFINBLID_00713 1046629.Ssal_01536 1.69e-192 534.0 COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,4H9Q7@91061|Bacilli 91061|Bacilli L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates fpg - 3.2.2.23,4.2.99.18 ko:K10563 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Fapy_DNA_glyco,H2TH,zf-FPG_IleRS NFINBLID_00714 1046629.Ssal_01539 3.34e-212 586.0 COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,4H9WF@91061|Bacilli 91061|Bacilli M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism era GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - ko:K03595 - - - - ko00000,ko03009,ko03029 - - - KH_2,MMR_HSR1 NFINBLID_00715 1046629.Ssal_01540 2.97e-86 254.0 COG0818@1|root,COG0818@2|Bacteria,1VEGR@1239|Firmicutes,4HNKN@91061|Bacilli 91061|Bacilli M Diacylglycerol kinase dgkA - 2.7.1.107,2.7.1.66 ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 - R02240,R05626 RC00002,RC00017 ko00000,ko00001,ko01000 - - iSB619.SA_RS07900 DAGK_prokar NFINBLID_00716 1046629.Ssal_01541 1.31e-113 326.0 COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,4HIIE@91061|Bacilli 91061|Bacilli S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA ybeY - - ko:K07042 - - - - ko00000,ko03009 - - - UPF0054 NFINBLID_00717 1046629.Ssal_01542 1.14e-191 533.0 COG3711@1|root,COG3711@2|Bacteria,1TT5A@1239|Firmicutes,4HC5Y@91061|Bacilli 91061|Bacilli K antiterminator licT - - ko:K03488 - - - - ko00000,ko03000 - - - CAT_RBD,PRD NFINBLID_00718 1046629.Ssal_01543 1.85e-136 386.0 COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,4HAZR@91061|Bacilli 91061|Bacilli L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO recR - - ko:K06187 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - RecR,Toprim_4 NFINBLID_00719 1046629.Ssal_01544 0.0 1306.0 COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,4HAFX@91061|Bacilli 91061|Bacilli M penicillin-binding protein pbp2b - - ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PBP_dimer,Transpeptidase NFINBLID_00720 1046629.Ssal_01545 6.56e-188 523.0 COG0063@1|root,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,4HBZC@91061|Bacilli 91061|Bacilli H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration nnrD - 4.2.1.136,5.1.99.6 ko:K17758,ko:K17759 - - - - ko00000,ko01000 - - - Carb_kinase,YjeF_N NFINBLID_00721 1046629.Ssal_01546 2e-200 555.0 COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,4H9Q6@91061|Bacilli 91061|Bacilli F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate folD GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R01220,R01655 RC00202,RC00578 ko00000,ko00001,ko00002,ko01000 - - - THF_DHG_CYH,THF_DHG_CYH_C NFINBLID_00722 1046629.Ssal_01547 6.43e-194 536.0 COG2267@1|root,COG2267@2|Bacteria,1V37Y@1239|Firmicutes,4ITDD@91061|Bacilli 91061|Bacilli I Alpha/beta hydrolase family - - - - - - - - - - - - Hydrolase_4 NFINBLID_00723 759913.SDSE_1600 2.42e-12 61.2 2DJ8A@1|root,304YV@2|Bacteria,1TXF8@1239|Firmicutes,4I6DK@91061|Bacilli,1MA5P@119603|Streptococcus dysgalactiae group 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00724 1046629.Ssal_01549 0.0 1359.0 COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,4HBCS@91061|Bacilli 91061|Bacilli P transporter of a GTP-driven Fe(2 ) uptake system feoB - - ko:K04759 - - - - ko00000,ko02000 9.A.8.1 - iSB619.SA_RS13395 FeoB_C,FeoB_N,Gate NFINBLID_00725 904306.HMPREF9192_1338 3.52e-101 294.0 COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,4HPFS@91061|Bacilli 91061|Bacilli P FeoA domain protein feoA - - ko:K04758 - - - - ko00000,ko02000 - - - FeoA NFINBLID_00726 1046629.Ssal_01552 2.57e-168 471.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran NFINBLID_00727 1046629.Ssal_01553 2.2e-151 426.0 COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,4IQKK@91061|Bacilli 91061|Bacilli P Binding-protein-dependent transport system inner membrane component - - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 NFINBLID_00728 1046629.Ssal_01554 3.31e-47 151.0 COG4703@1|root,COG4703@2|Bacteria,1VKD0@1239|Firmicutes,4HRGC@91061|Bacilli 91061|Bacilli S protein conserved in bacteria ykuJ - - - - - - - - - - - DUF1797 NFINBLID_00729 1046629.Ssal_01556 1.76e-232 640.0 COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,4H9X8@91061|Bacilli 91061|Bacilli E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline argF - 2.1.3.3 ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 M00029,M00844 R01398 RC00096 ko00000,ko00001,ko00002,ko01000 - - - OTCace,OTCace_N NFINBLID_00730 904306.HMPREF9192_1333 0.0 1404.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HA0V@91061|Bacilli 91061|Bacilli O Belongs to the ClpA ClpB family clpE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03697 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR NFINBLID_00731 1046629.Ssal_01558 1.11e-110 317.0 COG0494@1|root,COG0494@2|Bacteria,1VH6Q@1239|Firmicutes,4HQVJ@91061|Bacilli 91061|Bacilli L Belongs to the Nudix hydrolase family XK27_09440 - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX NFINBLID_00732 1046629.Ssal_01559 2.23e-65 199.0 2EBZ8@1|root,335YI@2|Bacteria,1VFRS@1239|Firmicutes,4HNUK@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF1827) XK27_09445 - - - - - - - - - - - DUF1827 NFINBLID_00733 1046629.Ssal_01560 2.45e-220 608.0 COG0673@1|root,COG0673@2|Bacteria,1TQSS@1239|Firmicutes,4HDXF@91061|Bacilli 91061|Bacilli S oxidoreductase - - - - - - - - - - - - GFO_IDH_MocA,GFO_IDH_MocA_C NFINBLID_00734 435842.HMPREF0848_00231 6.78e-289 790.0 COG2348@1|root,COG2348@2|Bacteria,1V181@1239|Firmicutes,4HEVU@91061|Bacilli 91061|Bacilli V FemAB family murN - - ko:K12554 ko00550,ko01100,map00550,map01100 - R08780 RC00055,RC00064 ko00000,ko00001,ko01000,ko01011 - - - FemAB NFINBLID_00735 1046629.Ssal_01562 1.08e-147 417.0 COG0398@1|root,COG0398@2|Bacteria 2|Bacteria M Pfam SNARE associated Golgi protein - - - - - - - - - - - - SNARE_assoc NFINBLID_00736 1046629.Ssal_01563 6.15e-139 393.0 2DMIQ@1|root,32RV1@2|Bacteria,1VGN9@1239|Firmicutes,4I0DZ@91061|Bacilli 91061|Bacilli S Domain of Unknown Function with PDB structure (DUF3862) - - - - - - - - - - - - DUF3862 NFINBLID_00739 1046629.Ssal_01564 9.51e-268 736.0 COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,4H9PX@91061|Bacilli 91061|Bacilli J ribosomal protein S1 rpsA - - ko:K02945 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - S1 NFINBLID_00742 1035187.HMPREF9959_0525 9.87e-22 87.0 29N96@1|root,30971@2|Bacteria,1U4J6@1239|Firmicutes,4IEAX@91061|Bacilli,2TPZ6@28037|Streptococcus mitis 91061|Bacilli S Protein of unknown function (DUF2969) - - - - - - - - - - - - DUF2969 NFINBLID_00743 1046629.Ssal_01567 2.9e-254 696.0 COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,4HASX@91061|Bacilli 91061|Bacilli E Aminotransferase ilvE - 2.6.1.42 ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00036,M00119,M00570 R01090,R01214,R02199,R10991 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - iYO844.BSU38550 Aminotran_4 NFINBLID_00744 904306.HMPREF9192_1319 0.0 1569.0 COG0188@1|root,COG0188@2|Bacteria,1TRE7@1239|Firmicutes,4HAQB@91061|Bacilli 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parC - - ko:K02621 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseA_C,DNA_topoisoIV NFINBLID_00746 1046629.Ssal_01572 0.0 1246.0 COG0187@1|root,COG0187@2|Bacteria,1TQCF@1239|Firmicutes,4H9UC@91061|Bacilli 91061|Bacilli L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule parE GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 - ko:K02622 - - - - ko00000,ko01000,ko02048,ko03032,ko03036 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim NFINBLID_00747 1046629.Ssal_01573 3.66e-139 394.0 COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4HC55@91061|Bacilli 91061|Bacilli I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP plsY - 2.3.1.15 ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R00851,R09380 RC00004,RC00039,RC00041 ko00000,ko00001,ko00002,ko01000,ko01004 - - - G3P_acyltransf NFINBLID_00748 759913.SDSE_1678 1.23e-18 82.8 2DJ7H@1|root,304X7@2|Bacteria,1TXCP@1239|Firmicutes,4I6AH@91061|Bacilli,1M9TG@119603|Streptococcus dysgalactiae group 91061|Bacilli L Helix-hairpin-helix DNA-binding motif class 1 - - - - - - - - - - - - HHH_5 NFINBLID_00749 1035184.HMPREF1042_0385 3.14e-42 139.0 2BXCI@1|root,346RD@2|Bacteria,1VYRT@1239|Firmicutes,4HYPP@91061|Bacilli,42DR8@671232|Streptococcus anginosus group 91061|Bacilli S Domain of unknown function (DUF1912) - - - - - - - - - - - - DUF1912 NFINBLID_00750 264199.stu0584 1.62e-213 591.0 COG2040@1|root,COG2040@2|Bacteria,1UHQ5@1239|Firmicutes,4HAS6@91061|Bacilli 91061|Bacilli H Homocysteine mmuM - 2.1.1.10 ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 - R00650 RC00003,RC00035 ko00000,ko00001,ko01000 - - - S-methyl_trans NFINBLID_00751 1046629.Ssal_01577 0.0 871.0 COG0833@1|root,COG0833@2|Bacteria,1UHNR@1239|Firmicutes 1239|Firmicutes E amino acid lysP - - ko:K02205,ko:K03293,ko:K16235,ko:K16236 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.10 - iHN637.CLJU_RS13850 AA_permease NFINBLID_00752 1046629.Ssal_01578 9.58e-144 405.0 COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,4HBXZ@91061|Bacilli 91061|Bacilli D Necessary for normal cell division and for the maintenance of normal septation engB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - ko:K03978 - - - - ko00000,ko03036 - - - MMR_HSR1 NFINBLID_00753 1046629.Ssal_01579 8.89e-288 786.0 COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli 91061|Bacilli O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP clpX GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - ko:K03544 ko04112,map04112 - - - ko00000,ko00001,ko03110 - - - AAA_2,ClpB_D2-small,zf-C4_ClpX NFINBLID_00754 435842.HMPREF0848_00215 2.97e-30 107.0 2DFKW@1|root,2ZS8U@2|Bacteria,1W5G0@1239|Firmicutes,4HZFD@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00755 904306.HMPREF9192_1309 9.21e-115 329.0 COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,4HIGJ@91061|Bacilli 91061|Bacilli H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis folA - 1.5.1.3 ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 M00126,M00840 R00936,R00937,R00939,R00940,R02235,R02236,R11765 RC00109,RC00110,RC00158 ko00000,ko00001,ko00002,ko01000 - - - DHFR_1 NFINBLID_00756 1046629.Ssal_01582 2.45e-212 585.0 COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,4HI1C@91061|Bacilli 91061|Bacilli F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis thyA - 2.1.1.45 ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 M00053 R02101 RC00219,RC00332 ko00000,ko00001,ko00002,ko01000 - - - Thymidylat_synt NFINBLID_00757 1046629.Ssal_01584 4.94e-268 735.0 COG3425@1|root,COG3425@2|Bacteria,1TR4K@1239|Firmicutes,4HA67@91061|Bacilli 91061|Bacilli I synthase mvaS - 2.3.3.10 ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 M00088,M00095 R01978 RC00004,RC00503 ko00000,ko00001,ko00002,ko01000 - - - HMG_CoA_synt_C,HMG_CoA_synt_N NFINBLID_00758 904306.HMPREF9192_1306 1.58e-284 780.0 COG1257@1|root,COG1257@2|Bacteria,1TPNY@1239|Firmicutes,4HBQ3@91061|Bacilli 91061|Bacilli C Belongs to the HMG-CoA reductase family mvaA - 1.1.1.88,2.3.1.9 ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 M00088,M00095,M00373,M00374,M00375 R00238,R01177,R02081 RC00004,RC00326,RC00644 ko00000,ko00001,ko00002,ko01000,ko04147 - - - HMG-CoA_red NFINBLID_00759 1046629.Ssal_01586 7.28e-101 292.0 COG0789@1|root,COG0789@2|Bacteria,1V7Z4@1239|Firmicutes 1239|Firmicutes K hmm pf08876 - - - - - - - - - - - - DUF1836 NFINBLID_00760 1046629.Ssal_01588 1.37e-149 422.0 COG1272@1|root,COG1272@2|Bacteria,1TTA5@1239|Firmicutes,4HDYT@91061|Bacilli 91061|Bacilli K protein, Hemolysin III hly-III - - ko:K11068 - - - - ko00000,ko02042 - - - HlyIII NFINBLID_00761 1046629.Ssal_01589 1.64e-39 130.0 COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,4HRGW@91061|Bacilli 91061|Bacilli KT PspC domain protein pspC - - - - - - - - - - - PspC NFINBLID_00762 904306.HMPREF9192_1302 2.48e-252 692.0 2DQ82@1|root,3357U@2|Bacteria,1VFZ3@1239|Firmicutes,4HNXV@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3114) - - - - - - - - - - - - DUF3114 NFINBLID_00763 1046629.Ssal_01591 1.14e-188 528.0 COG0596@1|root,COG0596@2|Bacteria,1V202@1239|Firmicutes,4HJ0U@91061|Bacilli 91061|Bacilli S hydrolases or acyltransferases (alpha beta hydrolase superfamily) - GO:0003674,GO:0003824,GO:0016787 - - - - - - - - - - Abhydrolase_1,Abhydrolase_6 NFINBLID_00764 1046629.Ssal_01592 0.0 1294.0 COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,4HABZ@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) thrS GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 ko:K01868 ko00970,map00970 M00359,M00360 R03663 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD NFINBLID_00766 1046629.Ssal_01594 2.12e-309 844.0 COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,4HA41@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 1 family protein pimB GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046872,GO:0071704,GO:1901576 2.4.1.337 ko:K19002 ko00561,ko01100,map00561,map01100 - R10850 RC00005,RC00059 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_transf_4,Glycos_transf_1 NFINBLID_00767 1046629.Ssal_01595 3.46e-242 665.0 COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,4HBKA@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 1 family protein dgs - 2.4.1.208 ko:K13677 ko00561,ko01100,map00561,map01100 - R05164 RC00005,RC00049 ko00000,ko00001,ko01000,ko01003 - GT4 - Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1 NFINBLID_00768 1046629.Ssal_01596 0.0 1533.0 COG3156@1|root,COG4932@1|root,COG3156@2|Bacteria,COG4932@2|Bacteria 2|Bacteria M domain protein - - - ko:K02460 ko03070,ko05111,map03070,map05111 M00331 - - ko00000,ko00001,ko00002,ko02044 3.A.15 - - Cna_B,Collagen_bind,FctA,Gram_pos_anchor,MucBP,SdrD_B,T2SSK,YSIRK_signal NFINBLID_00769 1046629.Ssal_01597 7.33e-152 428.0 COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,4HB8K@91061|Bacilli 91061|Bacilli E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively mtnN - 3.2.2.9 ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 M00034,M00609 R00194,R01401 RC00063,RC00318 ko00000,ko00001,ko00002,ko01000 - - - PNP_UDP_1 NFINBLID_00770 1046629.Ssal_01598 2.18e-43 142.0 2DC3Q@1|root,2ZCSA@2|Bacteria,1W5SW@1239|Firmicutes,4I23E@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00771 1046629.Ssal_01599 5.84e-123 351.0 COG0494@1|root,COG0494@2|Bacteria,1V6F5@1239|Firmicutes,4HII9@91061|Bacilli 91061|Bacilli L AdP-ribose pyrophosphatase nudF - 3.6.1.13 ko:K01515 ko00230,map00230 - R01054 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS07540,iYO844.BSU23610 NUDIX NFINBLID_00772 1046629.Ssal_01601 0.0 871.0 COG1207@1|root,COG1207@2|Bacteria,1TP88@1239|Firmicutes,4H9V5@91061|Bacilli 91061|Bacilli M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain glmU GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 M00362 R00416,R05332 RC00002,RC00004,RC00166 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,Hexapep_2,NTP_transf_3,NTP_transferase NFINBLID_00773 435842.HMPREF0848_00193 0.0 1662.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HBQJ@91061|Bacilli 91061|Bacilli P COG0474 Cation transport ATPase mgtA - 3.6.3.2 ko:K01531 - - - - ko00000,ko01000 3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase NFINBLID_00774 1046629.Ssal_00863 1.84e-74 233.0 2DN7R@1|root,32W08@2|Bacteria,1VBHE@1239|Firmicutes,4HMWG@91061|Bacilli 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 NFINBLID_00775 1046629.Ssal_01604 3.82e-192 534.0 COG1131@1|root,COG1131@2|Bacteria,1TRNT@1239|Firmicutes,4HB3P@91061|Bacilli 91061|Bacilli V ABC transporter, ATP-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_00776 1046629.Ssal_01605 1.7e-234 645.0 COG1304@1|root,COG1304@2|Bacteria,1TQZ3@1239|Firmicutes,4HAMV@91061|Bacilli 91061|Bacilli C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) fni GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095,M00096,M00364,M00365,M00366,M00367 R01123 RC00455 ko00000,ko00001,ko00002,ko01000 - - - FMN_dh NFINBLID_00777 1046629.Ssal_01606 1.61e-210 585.0 COG1577@1|root,COG1577@2|Bacteria,1TPKP@1239|Firmicutes,4HWXG@91061|Bacilli 91061|Bacilli I phosphomevalonate kinase mvaK2 - 2.7.4.2 ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R03245 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N NFINBLID_00778 904306.HMPREF9192_1286 6.01e-218 602.0 COG3407@1|root,COG3407@2|Bacteria,1TQXR@1239|Firmicutes,4HAM6@91061|Bacilli 91061|Bacilli I diphosphomevalonate decarboxylase mvaD - 4.1.1.33 ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 M00095 R01121 RC00453 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N NFINBLID_00779 904306.HMPREF9192_1285 2.86e-189 528.0 COG1577@1|root,COG1577@2|Bacteria,1TPVW@1239|Firmicutes,4IRCB@91061|Bacilli 91061|Bacilli I mevalonate kinase mvk - 2.7.1.36 ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 M00095 R02245 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - GHMP_kinases_C,GHMP_kinases_N NFINBLID_00780 904306.HMPREF9192_1283 4.85e-314 855.0 COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,4HBZF@91061|Bacilli 91061|Bacilli C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family merA - - - - - - - - - - - Pyr_redox_2,Pyr_redox_dim NFINBLID_00781 435842.HMPREF0848_00187 8.98e-161 453.0 COG2021@1|root,COG2021@2|Bacteria,1UJ13@1239|Firmicutes 1239|Firmicutes E alpha/beta hydrolase fold - - - - - - - - - - - - Abhydrolase_1 NFINBLID_00783 1046629.Ssal_01614 2.27e-248 684.0 COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,4HABX@91061|Bacilli 91061|Bacilli C Belongs to the AlaDH PNT family ald - 1.4.1.1 ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 - R00396 RC00008 ko00000,ko00001,ko01000 - - - AlaDh_PNT_C,AlaDh_PNT_N NFINBLID_00784 1046629.Ssal_01616 2.2e-272 745.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9WQ@91061|Bacilli 91061|Bacilli E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase hipO2 - - ko:K01436,ko:K21613 - - - - ko00000,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 NFINBLID_00785 264199.stu0553 6.56e-164 459.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 NFINBLID_00786 1046629.Ssal_01618 2.18e-147 416.0 COG1814@1|root,COG1814@2|Bacteria,1V6KW@1239|Firmicutes,4IPIC@91061|Bacilli 91061|Bacilli S VIT family - - - - - - - - - - - - VIT1 NFINBLID_00787 264199.stu0551 2.46e-172 482.0 COG2820@1|root,COG2820@2|Bacteria,1V6T2@1239|Firmicutes,4HCSE@91061|Bacilli 91061|Bacilli F Phosphorylase superfamily - - - - - - - - - - - - PNP_UDP_1 NFINBLID_00789 1046629.Ssal_01621 5.4e-39 129.0 COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,4HNID@91061|Bacilli 91061|Bacilli K Transcriptional XK27_00085 - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 NFINBLID_00790 1046629.Ssal_01622 9.64e-251 686.0 COG1054@1|root,COG1054@2|Bacteria,1TRG7@1239|Firmicutes,4HA0J@91061|Bacilli 91061|Bacilli S Belongs to the UPF0176 family ybfQ - - ko:K07146 - - - - ko00000 - - - Rhodanese,Rhodanese_C NFINBLID_00791 1046629.Ssal_01624 2.68e-160 449.0 COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,4HAG4@91061|Bacilli 91061|Bacilli G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion nagB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0008150,GO:0008152,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901135 3.5.99.6 ko:K02564 ko00520,ko01100,map00520,map01100 - R00765 RC00163 ko00000,ko00001,ko01000 - - - Glucosamine_iso NFINBLID_00792 1046629.Ssal_01625 4.12e-253 694.0 COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,4H9PT@91061|Bacilli 91061|Bacilli J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) queA GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 ko:K07568 - - - - ko00000,ko01000,ko03016 - - - Queuosine_synth NFINBLID_00793 1046629.Ssal_01626 0.0 1113.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein lmrA - - ko:K06147,ko:K18888 ko02010,map02010 M00706 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NFINBLID_00794 435842.HMPREF0848_00173 0.0 1090.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein msbA_1 - - ko:K18887 ko02010,map02010 M00706 - - ko00000,ko00001,ko00002,ko02000 3.A.1 - - ABC_membrane,ABC_tran NFINBLID_00795 1046629.Ssal_01629 1.27e-39 131.0 COG0583@1|root,COG0583@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - ko:K02051 - M00188 - - ko00000,ko00002,ko02000 3.A.1.16,3.A.1.17 - - HTH_1,LysR_substrate,NMT1_2 NFINBLID_00796 1046629.Ssal_01630 0.0 978.0 COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,4HA7U@91061|Bacilli 91061|Bacilli M Belongs to the BCCT transporter (TC 2.A.15) family opuD GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0008150,GO:0008324,GO:0008519,GO:0009266,GO:0009409,GO:0009628,GO:0015075,GO:0015101,GO:0015199,GO:0015651,GO:0015695,GO:0015696,GO:0015697,GO:0015838,GO:0022857,GO:0031460,GO:0034220,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0072337,GO:0072349,GO:0072488,GO:0098655 - ko:K05020 - - - - ko00000,ko02000 2.A.15.1.1,2.A.15.1.11 - - BCCT NFINBLID_00798 1214166.ALLG01000022_gene224 3.06e-183 521.0 COG0582@1|root,COG0582@2|Bacteria,1U90M@1239|Firmicutes,4IJ0I@91061|Bacilli,1WT9U@1307|Streptococcus suis 91061|Bacilli L Phage integrase SAM-like domain - - - - - - - - - - - - Phage_int_SAM_5,Phage_integrase NFINBLID_00799 1214166.ALLG01000022_gene225 4.62e-23 90.9 29R26@1|root,30C3A@2|Bacteria,1U93V@1239|Firmicutes,4IJ4N@91061|Bacilli,1WTPP@1307|Streptococcus suis 91061|Bacilli S Domain of unknown function (DUF3173) - - - - - - - - - - - - DUF3173 NFINBLID_00802 864570.HMPREF9189_0911 3.09e-89 268.0 2FBRT@1|root,343WK@2|Bacteria,1W0GT@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - NFINBLID_00804 888048.HMPREF8577_1852 6.42e-121 365.0 COG0860@1|root,COG0860@2|Bacteria 2|Bacteria M N-Acetylmuramoyl-L-alanine amidase amiB GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - iG2583_1286.G2583_4996 AMIN,Amidase_3,LysM NFINBLID_00806 1214184.ALKY01000034_gene4 4.41e-46 188.0 COG1196@1|root,COG1196@2|Bacteria,1UX38@1239|Firmicutes,4I2ID@91061|Bacilli,1WU1G@1307|Streptococcus suis 91061|Bacilli D LPXTG cell wall anchor motif - - - - - - - - - - - - Gram_pos_anchor NFINBLID_00807 888048.HMPREF8577_1876 5.83e-49 158.0 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4HN0W@91061|Bacilli 91061|Bacilli K Helix-turn-helix - - - - - - - - - - - - HTH_3 NFINBLID_00808 1201292.DR75_1119 9.43e-92 305.0 COG1132@1|root,COG1132@2|Bacteria,1TSY4@1239|Firmicutes,4HAJQ@91061|Bacilli,4AZ8Z@81852|Enterococcaceae 91061|Bacilli V ABC transporter transmembrane region - - 3.6.3.44 ko:K02021,ko:K06147,ko:K18104 ko01501,ko02010,map01501,map02010 M00700 - - ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.123,3.A.1.21 - - ABC_membrane,ABC_tran NFINBLID_00810 1437608.BBIA_1578 1.24e-20 95.9 2B6YP@1|root,31ZYT@2|Bacteria,2H32T@201174|Actinobacteria,4D1XQ@85004|Bifidobacteriales 201174|Actinobacteria - - - - - - - - - - - - - - - NFINBLID_00811 1114965.Spaf_1095 1.22e-154 435.0 COG1131@1|root,COG1131@2|Bacteria,1TSUA@1239|Firmicutes,4HEHW@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - AAA_21,ABC_tran NFINBLID_00812 446471.Xcel_0092 1.93e-31 116.0 2D1GW@1|root,32TAQ@2|Bacteria,2IQ3W@201174|Actinobacteria 201174|Actinobacteria S Transglutaminase-like superfamily - - - - - - - - - - - - Transglut_core3 NFINBLID_00814 66897.DJ64_06750 1.43e-30 134.0 COG0367@1|root,COG0367@2|Bacteria,2GMIY@201174|Actinobacteria 201174|Actinobacteria E Asparagine synthase - - 6.3.5.4 ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 - R00578 RC00010 ko00000,ko00001,ko01000,ko01002 - - - Asn_synthase NFINBLID_00816 626369.HMPREF0446_00425 5.15e-144 407.0 COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,4HG76@91061|Bacilli,27HWY@186828|Carnobacteriaceae 91061|Bacilli K Transcriptional regulatory protein, C terminal yycF1 - - ko:K20488 ko02020,ko02024,map02020,map02024 M00816 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C NFINBLID_00817 904306.HMPREF9192_1436 1.02e-85 270.0 COG0642@1|root,COG0642@2|Bacteria 2|Bacteria T Histidine kinase - - 2.7.13.3 ko:K10681,ko:K20487 ko02020,ko02024,map02020,map02024 M00468,M00816 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA NFINBLID_00818 1046629.Ssal_00123 2.28e-43 144.0 COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,4HBWU@91061|Bacilli 91061|Bacilli L COG1943 Transposase and inactivated derivatives - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp NFINBLID_00819 1046629.Ssal_00123 1.05e-40 137.0 COG1943@1|root,COG1943@2|Bacteria,1V1CM@1239|Firmicutes,4HBWU@91061|Bacilli 91061|Bacilli L COG1943 Transposase and inactivated derivatives - - - ko:K07491 - - - - ko00000 - - - Y1_Tnp NFINBLID_00821 435842.HMPREF0848_00168 1.96e-169 474.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli 91061|Bacilli KT Response regulator of the LytR AlgR family - - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg NFINBLID_00822 435842.HMPREF0848_00167 7.95e-291 796.0 COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,4HKY4@91061|Bacilli 91061|Bacilli T GHKL domain - - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 NFINBLID_00823 699248.SRA_00333 5.49e-61 199.0 COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,4IPIG@91061|Bacilli 91061|Bacilli L COG3547 Transposase and inactivated derivatives - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 NFINBLID_00824 904306.HMPREF9192_0370 0.0 1987.0 COG0739@1|root,COG0860@1|root,COG1705@1|root,COG1876@1|root,COG3757@1|root,COG0739@2|Bacteria,COG0860@2|Bacteria,COG1705@2|Bacteria,COG1876@2|Bacteria,COG3757@2|Bacteria,1V1F7@1239|Firmicutes,4ISN5@91061|Bacilli 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase - - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - GBS_Bsp-like,SH3_5,VanY,YSIRK_signal NFINBLID_00826 435842.HMPREF0848_00089 0.0 1110.0 COG1705@1|root,COG3942@1|root,COG1705@2|Bacteria,COG3942@2|Bacteria,1UIWC@1239|Firmicutes,4ISUH@91061|Bacilli 91061|Bacilli NU GBS Bsp-like repeat - - - - - - - - - - - - CHAP,GBS_Bsp-like,SH3_5,YSIRK_signal NFINBLID_00827 435842.HMPREF0848_01912 8.59e-221 609.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HCMP@91061|Bacilli 91061|Bacilli L Integrase - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve NFINBLID_00828 1046629.Ssal_00371 3.69e-95 278.0 COG2153@1|root,COG2153@2|Bacteria,1VA2J@1239|Firmicutes,4HKF5@91061|Bacilli 91061|Bacilli S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases yjcF GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - - - - - - - - - - Acetyltransf_10 NFINBLID_00829 1046629.Ssal_00372 6.12e-184 511.0 COG3338@1|root,COG3338@2|Bacteria,1V16J@1239|Firmicutes,4HA62@91061|Bacilli 91061|Bacilli P carbonic anhydrase cah - 4.2.1.1 ko:K01674 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Carb_anhydrase NFINBLID_00830 1046629.Ssal_00375 0.0 1565.0 COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,4H9RD@91061|Bacilli 91061|Bacilli C formate acetyltransferase' pflB - 2.3.1.54 ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 - R00212,R06987 RC00004,RC01181,RC02742,RC02833 ko00000,ko00001,ko01000 - - - Gly_radical,PFL-like NFINBLID_00831 904306.HMPREF9192_0701 4e-257 706.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HADJ@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII dinB GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 ko:K02346 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH NFINBLID_00833 1046629.Ssal_00380 3.3e-196 544.0 COG0834@1|root,COG0834@2|Bacteria,1V7WQ@1239|Firmicutes,4HK1Z@91061|Bacilli 91061|Bacilli ET ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 NFINBLID_00834 1046629.Ssal_00382 4.01e-208 577.0 COG0765@1|root,COG0765@2|Bacteria,1UZ2C@1239|Firmicutes,4HF77@91061|Bacilli 91061|Bacilli P ABC transporter (Permease yxeN - - ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 M00236,M00585,M00586 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.13 - - BPD_transp_1 NFINBLID_00835 904306.HMPREF9192_0705 1.08e-166 467.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein tcyN - 3.6.3.21 ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 M00234,M00236,M00585 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3,3.A.1.3.10,3.A.1.3.13,3.A.1.3.14 - - ABC_tran NFINBLID_00836 40041.SZO_03890 3.64e-14 67.8 29I01@1|root,304X3@2|Bacteria,1TXCH@1239|Firmicutes,4I6AC@91061|Bacilli,1M9T3@119603|Streptococcus dysgalactiae group 91061|Bacilli S Protein of unknown function (DUF4059) - - - - - - - - - - - - DUF4059 NFINBLID_00837 1046629.Ssal_00386 1.13e-218 603.0 COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,4HA4N@91061|Bacilli 91061|Bacilli C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family trxB - 1.8.1.9 ko:K00384 ko00450,map00450 - R02016,R03596,R09372 RC00013,RC02518,RC02873 ko00000,ko00001,ko01000 - - - Pyr_redox_2 NFINBLID_00838 904306.HMPREF9192_0710 3.02e-119 341.0 COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,4HGXT@91061|Bacilli 91061|Bacilli L Methyltransferase rsmD - 2.1.1.171 ko:K08316 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - Cons_hypoth95 NFINBLID_00839 1046629.Ssal_00388 5.35e-113 324.0 COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,4HH47@91061|Bacilli 91061|Bacilli H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate coaD GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 ko:K00954 ko00770,ko01100,map00770,map01100 M00120 R03035 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like NFINBLID_00840 264199.stu1647 7.5e-241 664.0 COG3480@1|root,COG3480@2|Bacteria,1TRUF@1239|Firmicutes,4HBAY@91061|Bacilli 91061|Bacilli T Belongs to the peptidase S16 family lon - - ko:K07177 ko02024,map02024 - - - ko00000,ko00001,ko01002 - - - Lon_C,PDZ_2 NFINBLID_00841 904306.HMPREF9192_0713 2.81e-232 638.0 COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,4H9N8@91061|Bacilli 91061|Bacilli S radical SAM protein ytqA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K07139 - - - - ko00000 - - - Radical_SAM,Radical_SAM_C NFINBLID_00842 264199.stu1645 1.13e-120 345.0 COG0144@1|root,COG0144@2|Bacteria,1UHQD@1239|Firmicutes,4HIMC@91061|Bacilli 91061|Bacilli J (SAM)-dependent mraW1 - - - - - - - - - - - rRNA_methylase NFINBLID_00844 1046629.Ssal_00394 0.0 1262.0 COG0025@1|root,COG0025@2|Bacteria,1TR4G@1239|Firmicutes,4HBJR@91061|Bacilli 91061|Bacilli P NhaP-type Na H and K H antiporters nhaP1 - - ko:K03316 - - - - ko00000 2.A.36 - - Na_H_Exchanger NFINBLID_00845 246201.SM12261_0265 7.29e-32 114.0 2BGH9@1|root,32AFE@2|Bacteria,1U4HU@1239|Firmicutes,4IE9N@91061|Bacilli,2TPX5@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00847 1046629.Ssal_00395 9.73e-181 503.0 COG1119@1|root,COG1119@2|Bacteria,1TRR4@1239|Firmicutes,4HB4U@91061|Bacilli 91061|Bacilli P abc transporter atp-binding protein ylmA - 3.6.3.34 ko:K02013 ko02010,map02010 M00240 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.14 - - ABC_tran NFINBLID_00848 1046629.Ssal_00397 5.78e-304 830.0 COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,4H9SB@91061|Bacilli 91061|Bacilli S COG1253 Hemolysins and related proteins containing CBS domains hlyX - - ko:K03699 - - - - ko00000,ko02042 - - - CBS,CorC_HlyC,DUF21 NFINBLID_00850 1046629.Ssal_00399 4.91e-202 558.0 COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,4HACV@91061|Bacilli 91061|Bacilli C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine pflA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.97.1.4 ko:K04069 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM NFINBLID_00852 1046629.Ssal_00402 1.25e-97 284.0 COG0589@1|root,COG0589@2|Bacteria,1V3NY@1239|Firmicutes,4HIP3@91061|Bacilli 91061|Bacilli T universal stress protein XK27_03180 - - - - - - - - - - - Usp NFINBLID_00853 1046629.Ssal_00403 4.15e-300 817.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HD83@91061|Bacilli 91061|Bacilli E Aminotransferase aspC - 2.6.1.2,2.6.1.66 ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 - R00258,R01215 RC00006,RC00008,RC00036 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 NFINBLID_00854 1046629.Ssal_00404 2.12e-180 503.0 COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,4HA9U@91061|Bacilli 91061|Bacilli K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor codY GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - ko:K03706 - - - - ko00000,ko03000 - - - CodY,HTH_CodY NFINBLID_00855 322159.STER_1598 5.85e-128 363.0 COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,4HFRS@91061|Bacilli 91061|Bacilli Q isochorismatase pncA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 - ko:K16788 - - - - ko00000,ko02000 2.A.88.5 - - Isochorismatase NFINBLID_00856 904306.HMPREF9192_0728 0.0 997.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family ascB - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 NFINBLID_00857 435842.HMPREF0848_01271 7.94e-272 746.0 COG1442@1|root,COG1442@2|Bacteria 2|Bacteria M lipopolysaccharide 3-alpha-galactosyltransferase activity - - - - - - - - - - - - Glyco_transf_8 NFINBLID_00858 435842.HMPREF0848_01270 1.39e-201 559.0 COG1216@1|root,COG1216@2|Bacteria,1V7WV@1239|Firmicutes 1239|Firmicutes H COG0463 Glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2 NFINBLID_00859 435842.HMPREF0848_01269 1.56e-236 659.0 COG0438@1|root,COG0438@2|Bacteria,1TQZR@1239|Firmicutes 1239|Firmicutes M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 - - - - - - - - - - - - - NFINBLID_00860 435842.HMPREF0848_01268 9.94e-297 816.0 COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli 91061|Bacilli M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon gtf1 - - - - - - - - - - - Glycos_transf_1 NFINBLID_00861 1046629.Ssal_00409 7.49e-64 195.0 COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,4HNNA@91061|Bacilli 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatC - 6.3.5.6,6.3.5.7 ko:K02435 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Glu-tRNAGln NFINBLID_00862 1114965.Spaf_1657 0.0 940.0 COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,4HBAZ@91061|Bacilli 91061|Bacilli J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) gatA - 6.3.5.6,6.3.5.7 ko:K02433 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - Amidase NFINBLID_00863 1046629.Ssal_00411 0.0 942.0 COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,4HAFB@91061|Bacilli 91061|Bacilli J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) gatB GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 ko:K02434 ko00970,ko01100,map00970,map01100 - R03905,R04212 RC00010 ko00000,ko00001,ko01000,ko03029 - - - GatB_N,GatB_Yqey NFINBLID_00865 1054460.SPPN_09980 0.0 978.0 COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,4HA1W@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 1 family celA - 3.2.1.86 ko:K01223 ko00010,ko00500,map00010,map00500 - R00839,R05133,R05134 RC00049,RC00171,RC00714 ko00000,ko00001,ko01000 - GT1 - Glyco_hydro_1 NFINBLID_00866 1054460.SPPN_09975 8.99e-42 137.0 COG4095@1|root,COG4095@2|Bacteria,1VF4D@1239|Firmicutes,4I0UK@91061|Bacilli 91061|Bacilli S PQ loop repeat - - - ko:K15383 - - - - ko00000,ko02000 9.A.58.2 - - PQ-loop NFINBLID_00867 862967.SIR_1124 4.78e-62 191.0 COG1440@1|root,COG1440@2|Bacteria,1VAE8@1239|Firmicutes,4HKQ2@91061|Bacilli,42ED8@671232|Streptococcus anginosus group 91061|Bacilli G PTS system, Lactose/Cellobiose specific IIB subunit celB - 2.7.1.196,2.7.1.205 ko:K02760 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIB NFINBLID_00868 373153.SPD_0280 0.0 943.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,4HEIQ@91061|Bacilli,1WUWZ@1313|Streptococcus pneumoniae 91061|Bacilli GKT Mga helix-turn-helix domain celR - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2,PTS_IIB NFINBLID_00869 1054460.SPPN_09960 4.76e-53 168.0 COG1447@1|root,COG1447@2|Bacteria,1VAWR@1239|Firmicutes,4HM7W@91061|Bacilli 91061|Bacilli G Phosphotransferase system cellobiose-specific component IIA celC - 2.7.1.196,2.7.1.205 ko:K02759 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.3.2 - - PTS_IIA NFINBLID_00870 171101.spr0281 1.19e-74 228.0 2E5MG@1|root,303YF@2|Bacteria,1TVHS@1239|Firmicutes,4I4RK@91061|Bacilli,1WUBA@1313|Streptococcus pneumoniae 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00871 170187.SP_0310 3.41e-97 295.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HDVN@91061|Bacilli,1WUD4@1313|Streptococcus pneumoniae 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celD - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC NFINBLID_00872 176090.SSIN_0689 5.15e-156 449.0 COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,4HDVN@91061|Bacilli 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celD - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC NFINBLID_00873 435842.HMPREF0848_01264 7.46e-79 235.0 2B9ZC@1|root,323D0@2|Bacteria,1VBNR@1239|Firmicutes,4HNA3@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00874 1114965.Spaf_1654 3.19e-241 664.0 COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4HABC@91061|Bacilli 91061|Bacilli E Dehydrogenase ydjL GO:0000721,GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 1.1.1.264,1.1.1.303,1.1.1.4 ko:K00004,ko:K00098 ko00650,map00650 - R02855,R02946,R05684,R10504 RC00089,RC00205,RC00525 ko00000,ko00001,ko01000 - - iYO844.BSU06240 ADH_N,ADH_zinc_N NFINBLID_00875 904306.HMPREF9192_0753 1.15e-190 532.0 COG0697@1|root,COG0697@2|Bacteria,1TR6G@1239|Firmicutes,4HAMD@91061|Bacilli 91061|Bacilli EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA NFINBLID_00876 904306.HMPREF9192_0754 2.61e-127 361.0 COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,4HGAV@91061|Bacilli 91061|Bacilli S hydrolase of the HAD superfamily yqeG - - ko:K07015 - - - - ko00000 - - - HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase NFINBLID_00877 1046629.Ssal_00415 9.31e-274 748.0 COG1161@1|root,COG1161@2|Bacteria,1TPM2@1239|Firmicutes,4HAAF@91061|Bacilli 91061|Bacilli S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis yqeH GO:0003674,GO:0003824,GO:0003924,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019219,GO:0019222,GO:0022613,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0042254,GO:0044085,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071840,GO:0080090,GO:0090329,GO:2000104,GO:2000112,GO:2000113 - ko:K06948 - - - - ko00000,ko03009 - - - MMR_HSR1 NFINBLID_00878 1046629.Ssal_00416 1.53e-63 194.0 COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,4HKC7@91061|Bacilli 91061|Bacilli J RNA-binding protein yhbY - - ko:K07574 - - - - ko00000,ko03009 - - - CRS1_YhbY NFINBLID_00879 1046629.Ssal_00417 6.18e-150 421.0 COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,4HGXK@91061|Bacilli 91061|Bacilli H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) nadD GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 ko:K00969 ko00760,ko01100,map00760,map01100 M00115 R00137,R03005 RC00002 ko00000,ko00001,ko00002,ko01000 - - - CTP_transf_like NFINBLID_00880 904306.HMPREF9192_0758 3.33e-136 385.0 COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,4HHRY@91061|Bacilli 91061|Bacilli H HD superfamily hydrolase involved in NAD metabolism yqeK - - - - - - - - - - - HD NFINBLID_00881 1046629.Ssal_00419 2.32e-75 225.0 COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,4HKEJ@91061|Bacilli 91061|Bacilli J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation rsfS GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - ko:K09710 - - - - ko00000,ko03009 - - - RsfS NFINBLID_00882 1046629.Ssal_00420 1.76e-176 491.0 COG0500@1|root,COG2226@2|Bacteria,1V24K@1239|Firmicutes,4HDFY@91061|Bacilli 91061|Bacilli Q Methyltransferase domain protein XK27_06665 - - - - - - - - - - - Methyltransf_25 NFINBLID_00883 435842.HMPREF0848_01254 3.23e-249 685.0 COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,4HAZJ@91061|Bacilli 91061|Bacilli S Belongs to the UPF0348 family ylbM - - - - - - - - - - - HIGH_NTase1 NFINBLID_00884 1046629.Ssal_00422 1.88e-52 165.0 COG2161@1|root,COG2161@2|Bacteria,1VM12@1239|Firmicutes,4HRMU@91061|Bacilli 91061|Bacilli D Antitoxin component of a toxin-antitoxin (TA) module yefM - - ko:K19159 - - - - ko00000,ko02048 - - - PhdYeFM_antitox NFINBLID_00885 1046629.Ssal_00423 1.21e-57 178.0 COG4115@1|root,COG4115@2|Bacteria,1VEN0@1239|Firmicutes,4HRVW@91061|Bacilli 91061|Bacilli S Addiction module toxin, Txe YoeB family yoeB - - ko:K19158 - - - - ko00000,ko01000,ko02048 - - - YoeB_toxin NFINBLID_00886 1046629.Ssal_00425 0.0 1339.0 COG0542@1|root,COG0542@2|Bacteria,1TRHP@1239|Firmicutes,4HAHZ@91061|Bacilli 91061|Bacilli O ATP-dependent Clp protease ATP-binding subunit clpL - - ko:K04086 - - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small,UVR NFINBLID_00888 1046629.Ssal_00427 1.98e-133 379.0 2AIHW@1|root,318ZT@2|Bacteria,1V92M@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - DUF4230 NFINBLID_00890 1046629.Ssal_00984 1.32e-63 198.0 COG1943@1|root,COG1943@2|Bacteria,1TSQ0@1239|Firmicutes,4HDZ0@91061|Bacilli 91061|Bacilli L COG1943 Transposase and inactivated derivatives isplu5A - - ko:K07491 - - - - ko00000 - - - Y1_Tnp NFINBLID_00892 904306.HMPREF9192_0767 7.19e-94 274.0 COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,4HIG2@91061|Bacilli 91061|Bacilli FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases hit - - ko:K02503 - - - - ko00000,ko04147 - - - HIT NFINBLID_00893 1046629.Ssal_00431 2.38e-168 471.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HA2B@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein ecsA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_00894 1046629.Ssal_00432 1.04e-223 619.0 COG4473@1|root,COG4473@2|Bacteria,1V9K7@1239|Firmicutes 1239|Firmicutes U Bacterial ABC transporter protein EcsB XK27_05910 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - EcsB NFINBLID_00895 1046629.Ssal_00433 2.95e-197 545.0 COG0510@1|root,COG0510@2|Bacteria,1UMFY@1239|Firmicutes,4HBF9@91061|Bacilli 91061|Bacilli M Phosphotransferase ytmP - - - - - - - - - - - APH NFINBLID_00896 1046629.Ssal_00434 7.53e-157 439.0 COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,4HC08@91061|Bacilli 91061|Bacilli J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA trmB GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 ko:K03439 - - - - ko00000,ko01000,ko03016 - - - Methyltransf_4 NFINBLID_00898 1046629.Ssal_00435 1.25e-271 744.0 COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,4HAAT@91061|Bacilli 91061|Bacilli S Flavoprotein ytfP - - ko:K07007 - - - - ko00000 - - - HI0933_like NFINBLID_00899 1046629.Ssal_00436 0.0 1127.0 COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli 91061|Bacilli E Belongs to the IlvD Edd family ilvD GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000 - - - ILVD_EDD NFINBLID_00900 904306.HMPREF9192_0775 1.09e-83 246.0 COG2151@1|root,COG2151@2|Bacteria,1VX9Z@1239|Firmicutes,4HXCM@91061|Bacilli 91061|Bacilli S cog cog2151 XK27_02560 - - - - - - - - - - - FeS_assembly_P NFINBLID_00901 1046629.Ssal_00439 5.18e-76 232.0 2EHT6@1|root,33BIW@2|Bacteria,1VNC1@1239|Firmicutes,4HRJ5@91061|Bacilli 91061|Bacilli S Protein of unknown function, DUF536 WQ51_02910 - - - - - - - - - - - DUF536,HTH_11,HTH_24 NFINBLID_00902 904306.HMPREF9192_0778 2.53e-133 378.0 COG0847@1|root,COG0847@2|Bacteria,1V8EQ@1239|Firmicutes,4HJYT@91061|Bacilli 91061|Bacilli L DNA polymerase III dnaQ - 2.7.7.7 ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - RNase_T NFINBLID_00903 904306.HMPREF9192_0780 4.21e-157 442.0 COG0789@1|root,COG0789@2|Bacteria,1UZ0H@1239|Firmicutes,4HGGU@91061|Bacilli 91061|Bacilli K transcriptional regulator, MerR family - - - - - - - - - - - - MerR_1 NFINBLID_00904 1046629.Ssal_00443 0.0 1597.0 COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,4HA2C@91061|Bacilli 91061|Bacilli V ABC transporter (Permease - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD NFINBLID_00905 1046629.Ssal_00444 2.75e-161 452.0 COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,4HB8D@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_00907 264199.stu1598 8.48e-56 174.0 COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,4HKH3@91061|Bacilli 91061|Bacilli S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection yaaK - - ko:K09747 - - - - ko00000 - - - YbaB_DNA_bd NFINBLID_00908 563038.HMPREF0851_01447 7.18e-61 193.0 2DEIC@1|root,2ZN3X@2|Bacteria,1W3A8@1239|Firmicutes,4HZMP@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00909 562983.HMPREF0433_00672 4.71e-103 310.0 2F5IH@1|root,33Y3W@2|Bacteria,1VWCK@1239|Firmicutes,4HW3I@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00911 888746.HMPREF9180_1568 6.99e-111 325.0 2EDPB@1|root,337J0@2|Bacteria,1VV0W@1239|Firmicutes,4HVVE@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00912 435842.HMPREF0848_01229 1.45e-163 461.0 COG2856@1|root,COG2856@2|Bacteria,1VPKW@1239|Firmicutes,4HZKQ@91061|Bacilli 91061|Bacilli E IrrE N-terminal-like domain - - - - - - - - - - - - Peptidase_M78 NFINBLID_00913 435842.HMPREF0848_01228 3.45e-142 403.0 COG2932@1|root,COG2932@2|Bacteria,1TQWX@1239|Firmicutes,4HY19@91061|Bacilli 91061|Bacilli K Peptidase S24-like protein - - - - - - - - - - - - HTH_3,Peptidase_S24 NFINBLID_00914 435842.HMPREF0848_01227 4.19e-101 293.0 2F0Z4@1|root,33U0S@2|Bacteria,1VUJF@1239|Firmicutes,4I1M0@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00915 873447.SPB_1682 6.03e-32 121.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH NFINBLID_00916 435842.HMPREF0848_01226 0.0 1120.0 28KEZ@1|root,2ZA17@2|Bacteria,1TPQ9@1239|Firmicutes,4HFER@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00917 435842.HMPREF0848_01225 0.0 1486.0 COG1215@1|root,COG1215@2|Bacteria,1TSD3@1239|Firmicutes,4HD23@91061|Bacilli 91061|Bacilli M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - 2.4.1.12 ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 - R02889 RC00005 ko00000,ko00001,ko01000,ko01003,ko02000 4.D.3.1.2,4.D.3.1.5,4.D.3.1.6 GT2 - Cellulose_synt,Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2,PilZ NFINBLID_00918 435842.HMPREF0848_01224 2.04e-193 542.0 COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,1TQ8C@1239|Firmicutes,4HDD4@91061|Bacilli 91061|Bacilli M COG0463, glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2,GtrA NFINBLID_00919 435842.HMPREF0848_01224 5.63e-11 61.6 COG0463@1|root,COG2246@1|root,COG0463@2|Bacteria,COG2246@2|Bacteria,1TQ8C@1239|Firmicutes,4HDD4@91061|Bacilli 91061|Bacilli M COG0463, glycosyltransferases involved in cell wall biogenesis - - - - - - - - - - - - Glycos_transf_2,GtrA NFINBLID_00920 435842.HMPREF0848_01223 9.24e-221 610.0 COG2199@1|root,COG2199@2|Bacteria,1UQA9@1239|Firmicutes,4HBNE@91061|Bacilli 91061|Bacilli T Diguanylate cyclase - - - - - - - - - - - - GGDEF,PAS_4,PAS_9 NFINBLID_00921 322159.STER_0445 1.18e-45 154.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB NFINBLID_00922 563038.HMPREF0851_01447 1.29e-56 182.0 2DEIC@1|root,2ZN3X@2|Bacteria,1W3A8@1239|Firmicutes,4HZMP@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00923 904306.HMPREF9192_0784 0.0 1469.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9ZI@91061|Bacilli 91061|Bacilli P E1-E2 ATPase ctpE - - ko:K12952 - - - - ko00000,ko01000 3.A.3.23 - - E1-E2_ATPase,Hydrolase NFINBLID_00924 904306.HMPREF9192_0472 2.31e-279 766.0 COG3464@1|root,COG3464@2|Bacteria,1VQIX@1239|Firmicutes 1239|Firmicutes L the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 NFINBLID_00925 1046629.Ssal_00451 5.38e-76 227.0 2C4MC@1|root,32RSW@2|Bacteria,1VCIA@1239|Firmicutes,4HKKA@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_00926 322159.STER_1555 6.19e-53 167.0 COG1605@1|root,COG1605@2|Bacteria 2|Bacteria E Chorismate mutase MA20_20425 - 2.5.1.19,4.2.1.10,4.2.99.21,5.4.99.5 ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 M00022,M00024,M00025 R01715,R03084,R03460,R06602 RC00350,RC00848,RC01549,RC02148,RC03116 ko00000,ko00001,ko00002,ko01000 - - - CM_2 NFINBLID_00927 904306.HMPREF9192_0786 0.0 884.0 COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HB31@91061|Bacilli 91061|Bacilli EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia trpE GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.3.27 ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Anth_synt_I_N,Chorismate_bind NFINBLID_00928 264199.stu1592 8.28e-135 381.0 COG0512@1|root,COG0512@2|Bacteria,1V4RM@1239|Firmicutes,4HHD8@91061|Bacilli 91061|Bacilli EH anthranilate trpG - 4.1.3.27 ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 M00023 R00985,R00986 RC00010,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - GATase NFINBLID_00929 904306.HMPREF9192_0788 3.66e-229 632.0 COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,4H9KQ@91061|Bacilli 91061|Bacilli F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) trpD GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0004425,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R00985,R00986,R01073 RC00010,RC00440,RC02148,RC02414 ko00000,ko00001,ko00002,ko01000 - - - Glycos_trans_3N,Glycos_transf_3 NFINBLID_00930 1046629.Ssal_00461 2.28e-172 482.0 COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,4HG9K@91061|Bacilli 91061|Bacilli E Belongs to the TrpC family trpC GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03508 RC00944 ko00000,ko00001,ko00002,ko01000 - - - IGPS NFINBLID_00931 904306.HMPREF9192_0790 6.96e-125 357.0 COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,4HK18@91061|Bacilli 91061|Bacilli E belongs to the TrpF family trpF - 5.3.1.24 ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 M00023 R03509 RC00945 ko00000,ko00001,ko00002,ko01000 - - - PRAI NFINBLID_00932 1046629.Ssal_00464 2.02e-290 793.0 COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,4H9WC@91061|Bacilli 91061|Bacilli E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine trpB GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20,5.3.1.24 ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722,R03509 RC00209,RC00210,RC00700,RC00701,RC00945,RC02868 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22640 PALP NFINBLID_00933 1046629.Ssal_00465 7.14e-183 509.0 COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,4HFQ8@91061|Bacilli 91061|Bacilli E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate trpA - 4.2.1.20 ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 M00023 R00674,R02340,R02722 RC00209,RC00210,RC00700,RC00701,RC02868 ko00000,ko00001,ko00002,ko01000 - - - Trp_syntA NFINBLID_00936 435842.HMPREF0848_01207 7.39e-98 284.0 COG3682@1|root,COG3682@2|Bacteria 2|Bacteria K negative regulation of transcription, DNA-templated copY - - - - - - - - - - - Penicillinase_R NFINBLID_00937 435842.HMPREF0848_01206 0.0 1330.0 COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,4HAI0@91061|Bacilli 91061|Bacilli P P-type ATPase copA - 3.6.3.54 ko:K17686 ko01524,ko04016,map01524,map04016 - R00086 RC00002 ko00000,ko00001,ko01000 3.A.3.5 - - E1-E2_ATPase,HMA,Hydrolase NFINBLID_00938 435842.HMPREF0848_01205 2.72e-42 138.0 COG2608@1|root,COG2608@2|Bacteria,1VK5F@1239|Firmicutes,4HR1Z@91061|Bacilli 91061|Bacilli P Heavy metal-associated domain protein copZ - - - - - - - - - - - HMA NFINBLID_00939 904306.HMPREF9192_0803 5.34e-245 673.0 COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,4H9KB@91061|Bacilli 91061|Bacilli F Belongs to the D-alanine--D-alanine ligase family ddl - 6.3.2.4 ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 - R01150 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Dala_Dala_lig_C,Dala_Dala_lig_N NFINBLID_00940 904306.HMPREF9192_2072 8.58e-149 420.0 COG0765@1|root,COG0765@2|Bacteria,1TRU3@1239|Firmicutes,4HGE1@91061|Bacilli 91061|Bacilli P ABC transporter (Permease glnP9 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 NFINBLID_00941 1046629.Ssal_00474 3.24e-148 418.0 COG0765@1|root,COG0765@2|Bacteria,1TR7R@1239|Firmicutes,4HGVA@91061|Bacilli 91061|Bacilli P ABC transporter (Permease glnP7 - - ko:K02029 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 NFINBLID_00942 1046629.Ssal_00475 3.65e-172 481.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4HDK7@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran NFINBLID_00943 904306.HMPREF9192_0805 5.47e-199 551.0 COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,4HFBQ@91061|Bacilli 91061|Bacilli ET ABC transporter substrate-binding protein cjaA - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 NFINBLID_00946 904306.HMPREF9192_0808 0.0 879.0 COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,4HACR@91061|Bacilli 91061|Bacilli M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein murF - 6.3.2.10 ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 - R04573,R04617 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M NFINBLID_00947 1046629.Ssal_00479 3.53e-150 423.0 COG5522@1|root,COG5522@2|Bacteria 2|Bacteria S Integral membrane protein (intg_mem_TP0381) ywaF - - - - - - - - - - - Intg_mem_TP0381 NFINBLID_00948 435842.HMPREF0848_01192 0.0 1035.0 COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,4HADS@91061|Bacilli 91061|Bacilli J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP prfC GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02837 - - - - ko00000,ko03012 - - - GTP_EFTU,GTP_EFTU_D2,RF3_C NFINBLID_00949 322159.STER_1531 2.87e-253 698.0 COG2211@1|root,COG2211@2|Bacteria,1TR4D@1239|Firmicutes,4HDCY@91061|Bacilli 91061|Bacilli G Permeases of the major facilitator superfamily yjbB - - - - - - - - - - - MFS_1,MFS_3 NFINBLID_00950 264199.stu1572 8.05e-198 549.0 COG1396@1|root,COG1396@2|Bacteria,1UZI0@1239|Firmicutes,4HC2C@91061|Bacilli 91061|Bacilli K Transcriptional activator, Rgg GadR MutR family rgg - - - - - - - - - - - HTH_3 NFINBLID_00951 1046629.Ssal_00485 6.98e-124 354.0 COG3859@1|root,COG3859@2|Bacteria,1V6YE@1239|Firmicutes,4HIJE@91061|Bacilli 91061|Bacilli S Thiamine transporter thiT GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K16789 - - - - ko00000,ko02000 2.A.88.3 - - Thia_YuaJ NFINBLID_00952 435842.HMPREF0848_01188 7.5e-83 245.0 arCOG12631@1|root,3172B@2|Bacteria,1V77G@1239|Firmicutes,4HJ0W@91061|Bacilli 91061|Bacilli S Bacterial PH domain yjqA - - - - - - - - - - - bPH_1 NFINBLID_00953 1046629.Ssal_00487 1.5e-200 557.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HCQ6@91061|Bacilli 91061|Bacilli P CorA-like protein corA - - - - - - - - - - - CorA NFINBLID_00954 435842.HMPREF0848_01186 0.0 961.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HAB3@91061|Bacilli 91061|Bacilli JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity cshA GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C NFINBLID_00957 435842.HMPREF0848_01185 4.82e-55 172.0 COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,4HNHJ@91061|Bacilli 91061|Bacilli L endonuclease containing a URI domain yazA - - ko:K07461 - - - - ko00000 - - - GIY-YIG NFINBLID_00958 1046629.Ssal_00490 1.01e-179 500.0 COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,4HA8W@91061|Bacilli 91061|Bacilli L Methyltransferase yabB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.223 ko:K07461,ko:K15460 - - - - ko00000,ko01000,ko03016 - - - GIY-YIG,MTS NFINBLID_00959 435842.HMPREF0848_01183 6.83e-198 551.0 COG0726@1|root,COG0726@2|Bacteria,1TYRH@1239|Firmicutes,4HHQN@91061|Bacilli 91061|Bacilli G deacetylase nodB3 - - - - - - - - - - - Polysacc_deac_1 NFINBLID_00960 264199.stu1563 1.76e-183 509.0 COG0204@1|root,COG0204@2|Bacteria,1U8N2@1239|Firmicutes,4HDQR@91061|Bacilli 91061|Bacilli I Acyltransferase plsC GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008374,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0042171,GO:0044464,GO:0071617,GO:0071944 2.3.1.51 ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 M00089 R02241,R09381 RC00004,RC00037,RC00039 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Acyltransferase NFINBLID_00961 1046629.Ssal_00493 4.2e-131 375.0 COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,4HKJ1@91061|Bacilli 91061|Bacilli L COG1555 DNA uptake protein and related DNA-binding proteins comEA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02237 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - HHH_3,SLBB NFINBLID_00962 1046629.Ssal_00495 0.0 1374.0 COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,4H9M4@91061|Bacilli 91061|Bacilli S Competence protein ComEC comEC - - ko:K02238 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1,3.A.11.2 - - Competence,DUF4131,Lactamase_B NFINBLID_00963 904306.HMPREF9192_0826 1.43e-290 795.0 COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,4H9KI@91061|Bacilli 91061|Bacilli M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine murA GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042221,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0070589,GO:0070887,GO:0071236,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R00660 RC00350 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU37100 EPSP_synthase NFINBLID_00964 1046629.Ssal_00498 6.86e-126 358.0 COG1670@1|root,COG1670@2|Bacteria,1V576@1239|Firmicutes,4HH6U@91061|Bacilli 91061|Bacilli J Acetyltransferase GNAT Family XK27_07830 - 2.3.1.128 ko:K03790 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 NFINBLID_00965 1046629.Ssal_00499 3.54e-294 804.0 COG4109@1|root,COG4109@2|Bacteria,1TPU6@1239|Firmicutes,4HB62@91061|Bacilli 91061|Bacilli K transcriptional regulator containing CBS domains ytoI - - - - - - - - - - - 4HBT,CBS,DRTGG,GntR,HTH_24 NFINBLID_00966 1046629.Ssal_00500 4.94e-212 585.0 COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,4H9S9@91061|Bacilli 91061|Bacilli E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed map - 3.4.11.18 ko:K01265 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M24 NFINBLID_00967 1046629.Ssal_00501 7.77e-209 579.0 COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,4H9MJ@91061|Bacilli 91061|Bacilli E Belongs to the UPF0761 family rbn - - ko:K07058 - - - - ko00000 - - - Virul_fac_BrkB NFINBLID_00968 1046629.Ssal_00502 3.45e-111 320.0 COG4708@1|root,COG4708@2|Bacteria,1V22G@1239|Firmicutes,4HGG2@91061|Bacilli 91061|Bacilli S cog cog4708 ccl GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - - - - - - - - - - QueT NFINBLID_00969 1046629.Ssal_00503 0.0 1241.0 COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,4HA1D@91061|Bacilli 91061|Bacilli L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA ligA GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 - R00382 RC00005 ko00000,ko00001,ko01000,ko03032,ko03400 - - - BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5 NFINBLID_00970 1046629.Ssal_00504 1.83e-235 648.0 COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,4H9WD@91061|Bacilli 91061|Bacilli I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase dagK GO:0003674,GO:0003824,GO:0004143,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.107 ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 - R02240 RC00002,RC00017 ko00000,ko00001,ko01000 - - - DAGK_cat NFINBLID_00972 1046629.Ssal_00505 1.04e-223 618.0 COG2378@1|root,COG2378@2|Bacteria 2|Bacteria K regulation of single-species biofilm formation yfjR GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - - - - - - - - - - HTH_11,HTH_DeoR,WYL NFINBLID_00974 1046629.Ssal_00507 2.07e-89 264.0 COG4708@1|root,COG4708@2|Bacteria,1V99E@1239|Firmicutes,4HXAN@91061|Bacilli 91061|Bacilli S QueT transporter - - - - - - - - - - - - QueT NFINBLID_00975 1046629.Ssal_00508 5.11e-204 563.0 COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,4HAIU@91061|Bacilli 91061|Bacilli L exodeoxyribonuclease III xth GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008309,GO:0008311,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2 ko:K01142 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - Exo_endo_phos NFINBLID_00977 888833.HMPREF9421_1657 1.99e-15 82.8 2DMBI@1|root,32H42@2|Bacteria,1VFT3@1239|Firmicutes,4HK1A@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF4767) yjdB - - - - - - - - - - - DUF4767 NFINBLID_00978 435842.HMPREF0848_01163 8.22e-214 590.0 COG0500@1|root,COG3615@1|root,COG0500@2|Bacteria,COG3615@2|Bacteria,1TSZK@1239|Firmicutes,4HJT1@91061|Bacilli 91061|Bacilli PQ tellurite resistance protein tehb tehB - 2.1.1.265 ko:K16868 - - - - ko00000,ko01000 - - - DUF1971,TehB NFINBLID_00979 1046629.Ssal_00513 4.91e-216 607.0 COG5549@1|root,COG5549@2|Bacteria 2|Bacteria O protein import - - - - - - - - - - - - Peptidase_M10 NFINBLID_00980 1046629.Ssal_00514 4.54e-158 445.0 COG3279@1|root,COG3279@2|Bacteria 2|Bacteria KT phosphorelay signal transduction system agrA - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg NFINBLID_00981 435842.HMPREF0848_01160 1.32e-268 741.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity - - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 NFINBLID_00983 1046629.Ssal_00517 1.87e-57 178.0 COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,4HKNN@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bS16 family rpsP GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02959 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S16 NFINBLID_00984 1046629.Ssal_00518 3.71e-49 156.0 COG1837@1|root,COG1837@2|Bacteria 2|Bacteria L Belongs to the UPF0109 family ylqC - - ko:K06960 - - - - ko00000 - - - KH_4 NFINBLID_00985 1046629.Ssal_00519 3.43e-298 814.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08370 Mur_ligase_C,Mur_ligase_M NFINBLID_00986 1046629.Ssal_00520 0.0 1171.0 COG0531@1|root,COG0531@2|Bacteria,1TQE1@1239|Firmicutes,4HAZH@91061|Bacilli 91061|Bacilli E amino acid ydaO GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - - - - - - - - - - AA_permease_2 NFINBLID_00987 1046629.Ssal_00521 4.02e-129 367.0 COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,4HAXS@91061|Bacilli 91061|Bacilli F gtp cyclohydrolase folE GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 ko:K01495 ko00790,ko01100,map00790,map01100 M00126,M00841,M00842,M00843 R00428,R04639,R05046,R05048 RC00263,RC00294,RC00323,RC00945,RC01188 ko00000,ko00001,ko00002,ko01000 - - - GTP_cyclohydroI NFINBLID_00988 1046629.Ssal_00522 3.39e-184 513.0 COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,4H9SY@91061|Bacilli 91061|Bacilli H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives folP GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 ko:K00796 ko00790,ko01100,map00790,map01100 M00126,M00841 R03066,R03067 RC00121,RC00842 ko00000,ko00001,ko00002,ko01000 - - - Pterin_bind NFINBLID_00989 435842.HMPREF0848_01152 0.0 1011.0 COG0366@1|root,COG0366@2|Bacteria,1TRKZ@1239|Firmicutes,4HC8C@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 13 family amy - 3.2.1.1 ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 - R02108,R02112,R11262 - ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF1939 NFINBLID_00990 1046629.Ssal_00524 8.32e-79 234.0 COG1539@1|root,COG1539@2|Bacteria,1VA0I@1239|Firmicutes,4HKKK@91061|Bacilli 91061|Bacilli H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin folB - 1.13.11.81,4.1.2.25,5.1.99.8 ko:K01633 ko00790,ko01100,map00790,map01100 M00126,M00840 R03504,R11037,R11073 RC00721,RC00943,RC01479,RC03333,RC03334 ko00000,ko00001,ko00002,ko01000 - - - FolB NFINBLID_00991 904306.HMPREF9192_0860 3.46e-99 289.0 COG0801@1|root,COG0801@2|Bacteria,1V6PR@1239|Firmicutes,4HIMG@91061|Bacilli 91061|Bacilli H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK - 2.7.6.3 ko:K00950 ko00790,ko01100,map00790,map01100 M00126,M00841 R03503 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - HPPK NFINBLID_00992 1046629.Ssal_00526 1.04e-211 586.0 COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,4HAD8@91061|Bacilli 91061|Bacilli M cell wall formation murB - 1.3.1.98 ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 - R03191,R03192 RC02639 ko00000,ko00001,ko01000,ko01011 - - - FAD_binding_4,MurB_C NFINBLID_00993 904306.HMPREF9192_0862 9.28e-271 741.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4H9MS@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system potA - 3.6.3.30,3.6.3.31 ko:K02010,ko:K11072 ko02010,map02010 M00190,M00299 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.10,3.A.1.11.1 - iSB619.SA_RS05380 ABC_tran,TOBE_2 NFINBLID_00994 435842.HMPREF0848_01147 2e-179 501.0 COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,4HAYS@91061|Bacilli 91061|Bacilli P ABC-type spermidine putrescine transport system, permease component I potB - - ko:K11071 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 NFINBLID_00995 322159.STER_1494 2.33e-167 469.0 COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,4H9ZC@91061|Bacilli 91061|Bacilli P ABC-type spermidine putrescine transport system, permease component II potC - - ko:K11070 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - - BPD_transp_1 NFINBLID_00996 904306.HMPREF9192_0865 2.5e-258 707.0 COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,4HAET@91061|Bacilli 91061|Bacilli P spermidine putrescine ABC transporter potD - - ko:K11069 ko02010,map02010 M00299 - - ko00000,ko00001,ko00002,ko02000 3.A.1.11.1 - iSB619.SA_RS05395 SBP_bac_8 NFINBLID_00997 904306.HMPREF9192_0867 1.37e-195 544.0 COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,4HGRC@91061|Bacilli 91061|Bacilli O HflC and HflK could regulate a protease hflC - - ko:K04087 - M00742 - - ko00000,ko00002,ko01000 - - - Band_7 NFINBLID_00998 904306.HMPREF9192_0869 5.58e-92 268.0 COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,4HJ7X@91061|Bacilli 91061|Bacilli E Lactoylglutathione lyase gloA - 4.4.1.5 ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 M00491 R02530 RC00004,RC00740 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.1.16,3.A.1.1.2 - - Glyoxalase NFINBLID_00999 1046629.Ssal_00536 1.54e-196 546.0 COG1940@1|root,COG1940@2|Bacteria,1TRQ7@1239|Firmicutes,4HE30@91061|Bacilli 91061|Bacilli GK ROK family - - - - - - - - - - - - ROK NFINBLID_01000 1046629.Ssal_00537 1.21e-265 727.0 COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,4HATT@91061|Bacilli 91061|Bacilli E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine serC GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 M00020,M00124 R04173,R05085 RC00006,RC00036 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_5 NFINBLID_01001 904306.HMPREF9192_0872 3.66e-132 374.0 COG1247@1|root,COG1247@2|Bacteria,1UIW7@1239|Firmicutes,4ISU9@91061|Bacilli 91061|Bacilli M Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_1 NFINBLID_01002 1046629.Ssal_00539 2.4e-277 759.0 COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,4H9PH@91061|Bacilli 91061|Bacilli EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family serA - 1.1.1.399,1.1.1.95 ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R01513 RC00031 ko00000,ko00001,ko00002,ko01000,ko04147 - - - 2-Hacid_dh,2-Hacid_dh_C,ACT_4 NFINBLID_01003 904306.HMPREF9192_0874 4.66e-93 274.0 COG0350@1|root,COG0350@2|Bacteria 2|Bacteria L methylated-DNA-[protein]-cysteine S-methyltransferase activity ogt GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63,3.2.2.20 ko:K00567,ko:K01246 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - DNA_binding_1,Methyltransf_1N NFINBLID_01004 1046629.Ssal_01688 1.19e-77 231.0 COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,4HKQQ@91061|Bacilli 91061|Bacilli P Belongs to the ArsC family yusI - 1.20.4.1 ko:K00537 - - - - ko00000,ko01000 - - - ArsC,Glutaredoxin NFINBLID_01006 322159.STER_1483 9.16e-74 222.0 COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes 1239|Firmicutes S Effector of murein hydrolase LrgA lrgA - - ko:K06518 - - - - ko00000,ko02000 1.E.14.2 - - LrgA NFINBLID_01007 904306.HMPREF9192_0878 1.31e-150 425.0 COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes 1239|Firmicutes M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses lrgB - - - - - - - - - - - LrgB NFINBLID_01008 1046629.Ssal_00557 1.2e-125 358.0 COG0546@1|root,COG0546@2|Bacteria,1V421@1239|Firmicutes,4HHYH@91061|Bacilli 91061|Bacilli S IA, variant 1 - - - - - - - - - - - - HAD_2 NFINBLID_01009 1046629.Ssal_00558 0.0 1268.0 COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,4H9Y6@91061|Bacilli 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrB GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 ko:K02470 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim NFINBLID_01010 1046629.Ssal_00559 0.0 1040.0 COG4477@1|root,COG4477@2|Bacteria,1TQR7@1239|Firmicutes,4HA15@91061|Bacilli 91061|Bacilli D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization ezrA GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000921,GO:0005575,GO:0005623,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0022402,GO:0022607,GO:0031106,GO:0032185,GO:0032506,GO:0034622,GO:0043933,GO:0044085,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051301,GO:0051302,GO:0051781,GO:0061640,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - ko:K06286 - - - - ko00000,ko03036 - - - EzrA NFINBLID_01011 1046629.Ssal_00560 2.3e-143 405.0 COG0560@1|root,COG0560@2|Bacteria,1V9R7@1239|Firmicutes,4HTNE@91061|Bacilli 91061|Bacilli E phosphoserine phosphatase serB - 3.1.3.3 ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 M00020 R00582 RC00017 ko00000,ko00001,ko00002,ko01000,ko01009 - - - HAD NFINBLID_01013 1046629.Ssal_00562 2.86e-191 533.0 COG0697@1|root,COG0697@2|Bacteria,1TYSF@1239|Firmicutes 1239|Firmicutes EG Permeases of the drug metabolite transporter (DMT) superfamily - - - - - - - - - - - - EamA NFINBLID_01015 1046629.Ssal_00565 2.46e-81 241.0 COG1765@1|root,COG1765@2|Bacteria 2|Bacteria O OsmC-like protein ycaO - - ko:K06889,ko:K07397,ko:K09136 - - - - ko00000,ko03009 - - - Hydrolase_4,OsmC,YcaO NFINBLID_01016 264199.stu1516 9.09e-79 236.0 COG2050@1|root,COG2050@2|Bacteria,1VN0K@1239|Firmicutes,4HM66@91061|Bacilli 91061|Bacilli Q protein possibly involved in aromatic compounds catabolism - - - ko:K02614 ko00360,map00360 - R09840 RC00004,RC00014 ko00000,ko00001,ko01000 - - - 4HBT NFINBLID_01017 883156.HMPREF9282_01673 1.16e-09 65.5 COG1397@1|root,COG1397@2|Bacteria,1V7HC@1239|Firmicutes,4H7XK@909932|Negativicutes 909932|Negativicutes O ADP-ribosylglycohydrolase - - - - - - - - - - - - - NFINBLID_01019 1046629.Ssal_00568 2.86e-160 450.0 COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,4H9VU@91061|Bacilli 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rsuA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19 ko:K06183 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 NFINBLID_01020 388919.SSA_0806 9.86e-10 54.3 29RNI@1|root,30CRU@2|Bacteria,1UA9S@1239|Firmicutes,4IKMB@91061|Bacilli,1WS04@1305|Streptococcus sanguinis 91061|Bacilli S Protein of unknown function (DUF4044) - - - - - - - - - - - - DUF4044 NFINBLID_01021 904306.HMPREF9192_0893 7.8e-315 857.0 COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,4H9P8@91061|Bacilli 91061|Bacilli S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control obg GO:0000003,GO:0000160,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0017076,GO:0019001,GO:0019954,GO:0023052,GO:0030436,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035556,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043934,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - ko:K03979 - - - - ko00000,ko01000,ko03009 - - - DUF1967,GTP1_OBG,MMR_HSR1 NFINBLID_01022 1321372.AQQB01000060_gene15 5.23e-25 94.4 29R2M@1|root,30C3R@2|Bacteria,1U94Q@1239|Firmicutes,4IJ5T@91061|Bacilli,1WTRS@1307|Streptococcus suis 91061|Bacilli - - XK27_00735 - - - - - - - - - - - - NFINBLID_01023 904306.HMPREF9192_0895 5.64e-173 483.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran NFINBLID_01024 1046629.Ssal_00574 0.0 1380.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TQUG@1239|Firmicutes,4HAJ5@91061|Bacilli 91061|Bacilli P ABC-type amino acid transport signal transduction systems periplasmic component domain glnP - - ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 M00227,M00236 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3,3.A.1.3.2 - - BPD_transp_1,SBP_bac_3 NFINBLID_01025 904306.HMPREF9192_0897 1.4e-210 583.0 COG1266@1|root,COG1266@2|Bacteria,1VA8S@1239|Firmicutes,4IQWI@91061|Bacilli 91061|Bacilli S CAAX amino terminal protease family protein - - - ko:K07052 - - - - ko00000 - - - Abi NFINBLID_01027 1046629.Ssal_00577 0.0 1274.0 COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,4HB81@91061|Bacilli 91061|Bacilli L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage uvrB - - ko:K03702 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - Helicase_C,ResIII,UVR,UvrB NFINBLID_01028 435842.HMPREF0848_01112 1.34e-103 300.0 COG1051@1|root,COG1051@2|Bacteria,1V3MM@1239|Firmicutes 1239|Firmicutes F Nudix family XK27_04400 - 3.6.1.55 ko:K03574,ko:K12944 - - - - ko00000,ko01000,ko03400 - - - NUDIX NFINBLID_01029 1046629.Ssal_00582 1.09e-182 509.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HJ2R@91061|Bacilli 91061|Bacilli ET ABC transporter XK27_04395 - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 NFINBLID_01030 1046629.Ssal_00583 6.55e-179 499.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes 1239|Firmicutes ET Belongs to the bacterial solute-binding protein 3 family - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 NFINBLID_01031 1046629.Ssal_00584 2.26e-268 734.0 COG0436@1|root,COG0436@2|Bacteria,1TQPD@1239|Firmicutes,4HE7P@91061|Bacilli 91061|Bacilli E Aminotransferase arcT - - - - - - - - - - - Aminotran_1_2 NFINBLID_01032 1046629.Ssal_00585 3.62e-174 487.0 COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,4HD16@91061|Bacilli 91061|Bacilli ET Belongs to the bacterial solute-binding protein 3 family artP - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 NFINBLID_01033 1046629.Ssal_00586 8.61e-28 101.0 COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,4HNPV@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bS21 family rpsU GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - ko:K02970 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S21 NFINBLID_01034 435842.HMPREF0848_01106 2.93e-65 201.0 COG1970@1|root,COG1970@2|Bacteria,1VA14@1239|Firmicutes,4HKIA@91061|Bacilli 91061|Bacilli M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell mscL - - ko:K03282 - - - - ko00000,ko02000 1.A.22.1 - - MscL NFINBLID_01035 1046629.Ssal_00588 0.0 1174.0 COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,4HAG2@91061|Bacilli 91061|Bacilli L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication dnaG - - ko:K02316 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2 NFINBLID_01036 1046629.Ssal_00589 2.49e-256 704.0 COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,4HB1H@91061|Bacilli 91061|Bacilli K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth sigA - - ko:K03086 - - - - ko00000,ko03021 - - - Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4 NFINBLID_01037 1046629.Ssal_00591 1.43e-73 220.0 COG2151@1|root,COG2151@2|Bacteria,1V9YV@1239|Firmicutes,4HKC6@91061|Bacilli 91061|Bacilli K metal-sulfur cluster biosynthetic enzyme yitW - - - - - - - - - - - FeS_assembly_P NFINBLID_01038 1046629.Ssal_00592 4.4e-217 599.0 COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,4HC2Z@91061|Bacilli 91061|Bacilli M COG0463, glycosyltransferases involved in cell wall biogenesis yfdH - - ko:K12999,ko:K20534 - - - - ko00000,ko01000,ko01003,ko01005,ko02000 4.D.2.1.9 GT2 - Glycos_transf_2 NFINBLID_01039 904306.HMPREF9192_0913 0.0 895.0 2EPWD@1|root,33HGX@2|Bacteria,1VQBK@1239|Firmicutes,4HUQ1@91061|Bacilli 91061|Bacilli S Glucosyl transferase GtrII - - - - - - - - - - - - Glucos_trans_II NFINBLID_01040 904306.HMPREF9192_0914 1.64e-204 565.0 COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,4HBXF@91061|Bacilli 91061|Bacilli M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose rfbD - 1.1.1.133 ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 M00793 R02777 RC00182 ko00000,ko00001,ko00002,ko01000 - - - RmlD_sub_bind NFINBLID_01041 904306.HMPREF9192_0915 1.24e-278 764.0 COG2244@1|root,COG2244@2|Bacteria,1V1RP@1239|Firmicutes,4IR8D@91061|Bacilli 91061|Bacilli S membrane protein involved in the export of O-antigen and teichoic acid - - - - - - - - - - - - Polysacc_synt,Polysacc_synt_C NFINBLID_01042 904306.HMPREF9192_0916 4.12e-225 620.0 COG1215@1|root,COG1215@2|Bacteria,1V0TF@1239|Firmicutes,4ISVG@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 2 family protein - - - - - - - - - - - - Glyco_trans_1_2,Glycos_transf_2 NFINBLID_01043 322159.STER_1441 5.03e-230 633.0 COG1216@1|root,COG1216@2|Bacteria,1V3XP@1239|Firmicutes,4HQNP@91061|Bacilli 91061|Bacilli S Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 NFINBLID_01044 904306.HMPREF9192_0918 2.99e-163 457.0 COG1215@1|root,COG1215@2|Bacteria,1UHQZ@1239|Firmicutes,4IS6R@91061|Bacilli 91061|Bacilli M group 2 family protein arnC - - ko:K00786 - - - - ko00000,ko01000 - - - Glycos_transf_2 NFINBLID_01045 1046629.Ssal_00599 3.81e-57 179.0 2EVMS@1|root,33P1S@2|Bacteria,1VPQZ@1239|Firmicutes 1239|Firmicutes S Uncharacterized conserved protein (DUF2304) - - - ko:K09153 - - - - ko00000 - - - DUF2304 NFINBLID_01046 904306.HMPREF9192_0920 1.41e-197 546.0 COG1216@1|root,COG1216@2|Bacteria,1UI19@1239|Firmicutes 1239|Firmicutes S Glycosyltransferase group 2 family protein - - - - - - - - - - - - Glycos_transf_2 NFINBLID_01047 862967.SIR_0959 1.29e-145 427.0 2A7KX@1|root,30412@2|Bacteria,1TVS9@1239|Firmicutes,4I41E@91061|Bacilli,42DU2@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01048 1046629.Ssal_00601 0.0 1776.0 COG0438@1|root,COG1215@1|root,COG3754@1|root,COG0438@2|Bacteria,COG1215@2|Bacteria,COG3754@2|Bacteria,1UJI4@1239|Firmicutes,4HNC8@91061|Bacilli 91061|Bacilli M Glycosyltransferase like family 2 - - - - - - - - - - - - Glycos_transf_2 NFINBLID_01049 904306.HMPREF9192_0922 1.11e-277 762.0 COG4713@1|root,COG4713@2|Bacteria 2|Bacteria M Psort location CytoplasmicMembrane, score - - - - - - - - - - - - DUF2142 NFINBLID_01050 1046629.Ssal_00603 1.64e-282 774.0 COG0438@1|root,COG0438@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups - - - ko:K00754 - - - - ko00000,ko01000 - GT4 - Glyco_transf_4,Glycos_transf_1 NFINBLID_01051 904306.HMPREF9192_0924 7.51e-285 777.0 COG0438@1|root,COG0438@2|Bacteria,1V7K7@1239|Firmicutes,4HA9A@91061|Bacilli 91061|Bacilli M Domain of unknown function (DUF1972) rgpA - - ko:K12996 - - - - ko00000,ko01000,ko01003,ko01005 - GT4 - DUF1972,Glycos_transf_1 NFINBLID_01052 904306.HMPREF9192_0925 2.28e-221 610.0 COG0463@1|root,COG0463@2|Bacteria,1V7IQ@1239|Firmicutes,4HK7R@91061|Bacilli 91061|Bacilli M Glycosyltransferase, group 2 family protein rgpB - - ko:K12997 - - - - ko00000,ko01000,ko01003,ko01005 - GT2 - Glycos_transf_2 NFINBLID_01053 1046629.Ssal_00608 1.09e-181 506.0 COG1682@1|root,COG1682@2|Bacteria,1TY8I@1239|Firmicutes 1239|Firmicutes GM Transport permease protein - - - ko:K01992,ko:K09690,ko:K09692 ko02010,map02010 M00250,M00251,M00254 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.103,3.A.1.104 - - ABC2_membrane NFINBLID_01054 904306.HMPREF9192_0927 1.31e-285 780.0 COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,4HC6N@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system rgpD - 3.6.3.40 ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 M00250,M00251,M00254 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1,3.A.1.103,3.A.1.104 - - ABC_tran,Wzt_C NFINBLID_01055 1046629.Ssal_00610 0.0 957.0 COG3754@1|root,COG3754@2|Bacteria 2|Bacteria M Rhamnan synthesis protein F rgpF - - ko:K07272 - - - - ko00000,ko01000,ko01003,ko01005 - - - RgpF NFINBLID_01056 322159.STER_1430 1.32e-153 432.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli 91061|Bacilli E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC NFINBLID_01057 1046629.Ssal_00612 3.04e-165 462.0 COG2071@1|root,COG2071@2|Bacteria,1V1KC@1239|Firmicutes,4HI59@91061|Bacilli 91061|Bacilli T peptidase C26 - - - ko:K07010 - - - - ko00000,ko01002 - - - Peptidase_C26 NFINBLID_01058 1046629.Ssal_00613 3.68e-151 425.0 COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,4HB7Q@91061|Bacilli 91061|Bacilli K Modulates transcription in response to changes in cellular NADH NAD( ) redox state rex - - ko:K01926 - - - - ko00000,ko03000 - - - CoA_binding,Put_DNA-bind_N NFINBLID_01059 1046629.Ssal_00614 1.25e-78 233.0 2DHWG@1|root,32U9W@2|Bacteria,1VDSF@1239|Firmicutes,4HP9N@91061|Bacilli 91061|Bacilli S Putative amino acid metabolism XK27_04120 - - - - - - - - - - - DUF1831 NFINBLID_01060 1046629.Ssal_00615 1.34e-257 707.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HA6H@91061|Bacilli 91061|Bacilli E Cysteine desulfurase iscS - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 NFINBLID_01061 1046629.Ssal_00616 3.93e-223 616.0 COG0462@1|root,COG0462@2|Bacteria,1TQ4I@1239|Firmicutes,4HDRN@91061|Bacilli 91061|Bacilli F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) prs2 - 2.7.6.1 ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 M00005 R01049 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000 - - - Pribosyl_synth,Pribosyltran_N NFINBLID_01062 904306.HMPREF9192_0936 3.35e-131 372.0 COG4116@1|root,COG4116@2|Bacteria,1VA56@1239|Firmicutes,4HMNE@91061|Bacilli 91061|Bacilli S Adenylate cyclase yjbK - - - - - - - - - - - CYTH NFINBLID_01063 264199.stu1459 5.79e-154 433.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HA3Q@91061|Bacilli 91061|Bacilli S Gtp pyrophosphokinase yjbM GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K07816 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT NFINBLID_01064 264199.stu1457 5.67e-196 543.0 COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,4HB08@91061|Bacilli 91061|Bacilli H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP nadK GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 ko:K00858 ko00760,ko01100,map00760,map01100 - R00104 RC00002,RC00078 ko00000,ko00001,ko01000 - - iSB619.SA_RS04895 NAD_kinase NFINBLID_01065 904306.HMPREF9192_0939 1.05e-219 605.0 COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,4HBRY@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil yjbO GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 NFINBLID_01066 1046629.Ssal_00621 9.68e-226 623.0 COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,4H9VH@91061|Bacilli 91061|Bacilli C phosphate acetyltransferase pta - 2.3.1.8,3.6.3.21 ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00236,M00357,M00579 R00230,R00921 RC00004,RC02746,RC02816 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - iSB619.SA_RS03155 PTA_PTB NFINBLID_01067 904306.HMPREF9192_0941 0.0 1189.0 COG4166@1|root,COG4166@2|Bacteria,1TQVS@1239|Firmicutes,4HCCB@91061|Bacilli 91061|Bacilli E ABC transporter, substrate-binding protein, family 5 amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 NFINBLID_01068 1046629.Ssal_00622 0.0 1075.0 COG4166@1|root,COG4166@2|Bacteria,1TQVS@1239|Firmicutes,4HCCB@91061|Bacilli 91061|Bacilli E ABC transporter, substrate-binding protein, family 5 amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00239,M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 NFINBLID_01069 1046629.Ssal_00624 0.0 956.0 COG0601@1|root,COG0601@2|Bacteria,1UY5U@1239|Firmicutes,4HEZK@91061|Bacilli 91061|Bacilli P ABC transporter (Permease amiC GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1 NFINBLID_01070 1046629.Ssal_00625 4.05e-213 589.0 COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HE8S@91061|Bacilli 91061|Bacilli P ABC transporter (Permease amiD - - ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - BPD_transp_1,OppC_N NFINBLID_01071 904306.HMPREF9192_0944 4.66e-257 705.0 COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,4H9MR@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily amiE GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY NFINBLID_01072 1046629.Ssal_00627 4.08e-218 602.0 COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,4HCM4@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily amiF GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - ABC_tran,oligo_HPY NFINBLID_01073 1046629.Ssal_00628 9.09e-166 466.0 COG1131@1|root,COG1131@2|Bacteria,1VF25@1239|Firmicutes 1239|Firmicutes V Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - NFINBLID_01074 1046629.Ssal_00629 4.8e-158 444.0 COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,4HGHM@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein skfE - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_01075 1046629.Ssal_00630 2.84e-82 243.0 COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,4HNIT@91061|Bacilli 91061|Bacilli K Transcriptional ytrA - - ko:K07979 - - - - ko00000,ko03000 - - - GntR NFINBLID_01076 1046629.Ssal_00631 3.03e-186 518.0 COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,4IPK2@91061|Bacilli 91061|Bacilli S overlaps another CDS with the same product name - - - - - - - - - - - - Hydrolase_3 NFINBLID_01077 1046629.Ssal_00632 3.54e-189 526.0 COG0561@1|root,COG0561@2|Bacteria,1TR2E@1239|Firmicutes,4HGA9@91061|Bacilli 91061|Bacilli S overlaps another CDS with the same product name XK27_02985 - - - - - - - - - - - Hydrolase_3 NFINBLID_01078 1046629.Ssal_00633 1.25e-261 725.0 COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,4HA6A@91061|Bacilli 91061|Bacilli U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) ftsY - - ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2,3.A.5.7 - - SRP54,SRP54_N NFINBLID_01079 1046629.Ssal_00636 4.34e-145 409.0 COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,4HAYW@91061|Bacilli 91061|Bacilli F Essential for recycling GMP and indirectly, cGMP gmk GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 ko:K00942 ko00230,ko01100,map00230,map01100 M00050 R00332,R02090 RC00002 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15680 Guanylate_kin NFINBLID_01080 1046629.Ssal_00637 1.37e-61 189.0 COG1758@1|root,COG1758@2|Bacteria 2|Bacteria K DNA-directed 5'-3' RNA polymerase activity rpoZ GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb6 NFINBLID_01081 1046629.Ssal_00638 0.0 1537.0 COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,4H9WW@91061|Bacilli 91061|Bacilli L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA priA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K04066 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,ResIII NFINBLID_01082 435842.HMPREF0848_01065 2.26e-216 598.0 COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,4HART@91061|Bacilli 91061|Bacilli J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus fmt GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 ko:K00604 ko00670,ko00970,map00670,map00970 - R03940 RC00026,RC00165 ko00000,ko00001,ko01000 - - iSB619.SA_RS06010 Formyl_trans_C,Formyl_trans_N NFINBLID_01083 1046629.Ssal_00641 5.38e-308 840.0 COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,4HBQ6@91061|Bacilli 91061|Bacilli J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA sun GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 ko:K03500 - - - - ko00000,ko01000,ko03009 - - - Methyltr_RsmB-F,Methyltr_RsmF_N,NusB NFINBLID_01084 1046629.Ssal_00642 2.57e-173 484.0 COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,4HCDR@91061|Bacilli 91061|Bacilli T phosphatase stp - 3.1.3.16 ko:K20074 - - - - ko00000,ko01000,ko01009 - - - PP2C,PP2C_2 NFINBLID_01085 1046629.Ssal_00643 0.0 1041.0 COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,1TP3F@1239|Firmicutes,4H9KD@91061|Bacilli 91061|Bacilli KLT serine threonine protein kinase prkC GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 ko:K08884,ko:K12132 - - - - ko00000,ko01000,ko01001 - - - PASTA,Pkinase NFINBLID_01086 1046629.Ssal_00644 2.21e-137 392.0 COG1226@1|root,COG1226@2|Bacteria,1V285@1239|Firmicutes,4I17E@91061|Bacilli 91061|Bacilli P Ion transport protein - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2 NFINBLID_01087 435842.HMPREF0848_01061 3.48e-151 426.0 COG4758@1|root,COG4758@2|Bacteria,1V3D0@1239|Firmicutes,4HDIA@91061|Bacilli 91061|Bacilli S Membrane yvqF - - ko:K11622 ko02020,map02020 - - - ko00000,ko00001 - - - DUF2154 NFINBLID_01088 904306.HMPREF9192_0961 3.44e-219 607.0 COG4585@1|root,COG4585@2|Bacteria,1TPDG@1239|Firmicutes,4HC7E@91061|Bacilli 91061|Bacilli T Histidine kinase vraS - 2.7.13.3 ko:K07681,ko:K11617 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 NFINBLID_01089 322159.STER_1387 5.45e-146 412.0 COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,4HA4B@91061|Bacilli 91061|Bacilli K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain vraR - - ko:K07694,ko:K11618 ko02020,map02020 M00480,M00481,M00754 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg NFINBLID_01092 1046629.Ssal_00648 1.3e-121 347.0 COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,4HH3H@91061|Bacilli 91061|Bacilli J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes rimM - - ko:K02860 - - - - ko00000,ko03009 - - - PRC,RimM NFINBLID_01093 1046629.Ssal_00649 1.98e-174 486.0 COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,4HBFV@91061|Bacilli 91061|Bacilli J Belongs to the RNA methyltransferase TrmD family trmD GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 ko:K00554 - - R00597 RC00003,RC00334 ko00000,ko01000,ko03016 - - - tRNA_m1G_MT NFINBLID_01094 1046629.Ssal_00650 1.84e-237 653.0 COG0492@1|root,COG0492@2|Bacteria,1TRPN@1239|Firmicutes,4H9V7@91061|Bacilli 91061|Bacilli C Ferredoxin--NADP reductase yumC - 1.18.1.2,1.19.1.1 ko:K21567 - - - - ko00000,ko01000 - - iYO844.BSU32110 Pyr_redox_2 NFINBLID_01095 1046629.Ssal_00651 0.0 1463.0 COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,4H9WA@91061|Bacilli 91061|Bacilli D Belongs to the FtsK SpoIIIE SftA family ftsK GO:0000003,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0019954,GO:0030436,GO:0031323,GO:0031326,GO:0032502,GO:0043934,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K03466 - - - - ko00000,ko03036 3.A.12 - - FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma NFINBLID_01096 1046629.Ssal_00653 0.0 1434.0 COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,4HBP5@91061|Bacilli 91061|Bacilli G belongs to the glycosyl hydrolase 13 family pulA - 3.2.1.41 ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 - R02111 - ko00000,ko00001,ko01000 - CBM48,GH13 - Alpha-amylase,CBM_48,PUD NFINBLID_01097 1046629.Ssal_00654 0.0 1324.0 COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,4HAPM@91061|Bacilli 91061|Bacilli G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position glgB GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 M00565 R02110 - ko00000,ko00001,ko00002,ko01000,ko04147 - CBM48,GH13 - Alpha-amylase,Alpha-amylase_C,CBM_48 NFINBLID_01098 1046629.Ssal_00655 8.89e-251 691.0 COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,4HAZX@91061|Bacilli 91061|Bacilli H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans glgC - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase NFINBLID_01099 1046629.Ssal_00656 1.46e-232 644.0 COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,4H9UQ@91061|Bacilli 91061|Bacilli G glucose-1-phosphate adenylyltransferase glgD - 2.7.7.27 ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 M00565 R00948 RC00002 ko00000,ko00001,ko00002,ko01000 - - - Hexapep,NTP_transferase NFINBLID_01100 1046629.Ssal_00657 0.0 969.0 COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,4HAVA@91061|Bacilli 91061|Bacilli G Synthesizes alpha-1,4-glucan chains using ADP-glucose glgA GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 M00565 R02421 RC00005 ko00000,ko00001,ko00002,ko01000,ko01003 - GT5 - Glyco_transf_5,Glycos_transf_1 NFINBLID_01101 1046629.Ssal_00658 0.0 1582.0 COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,4H9XI@91061|Bacilli 91061|Bacilli G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties glgP GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 - R02111 - ko00000,ko00001,ko01000 - GT35 iYO844.BSU30940 Phosphorylase NFINBLID_01102 1046629.Ssal_00659 2.46e-126 360.0 COG0454@1|root,COG0456@2|Bacteria,1VEW7@1239|Firmicutes,4HPE4@91061|Bacilli 91061|Bacilli K Acetyltransferase GNAT Family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 NFINBLID_01103 1046629.Ssal_00660 0.0 982.0 2DI63@1|root,32UAI@2|Bacteria,1VBKU@1239|Firmicutes,4HUJH@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3114) - - - - - - - - - - - - DUF1310,DUF3114 NFINBLID_01107 999425.HMPREF9186_00510 0.0 1477.0 COG1181@1|root,COG2918@1|root,COG1181@2|Bacteria,COG2918@2|Bacteria,1TPGX@1239|Firmicutes,4HAMJ@91061|Bacilli 91061|Bacilli H Belongs to the glutamate--cysteine ligase type 1 family gshF - 6.3.2.2 ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 M00118,M00582 R00894,R10993 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ATP-grasp_3,Dala_Dala_lig_C,GARS_A,Glu_cys_ligase NFINBLID_01108 904306.HMPREF9192_0998 0.0 1024.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NFINBLID_01109 1046629.Ssal_00665 0.0 1165.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein ndvA - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NFINBLID_01110 435842.HMPREF0848_01040 1.14e-237 662.0 COG0488@1|root,COG0488@2|Bacteria,1TU6J@1239|Firmicutes,4HDY2@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein XK27_10075 - - - - - - - - - - - ABC_tran NFINBLID_01111 888808.HMPREF9380_1654 3.38e-12 75.1 29RP7@1|root,30CSI@2|Bacteria,1UAAN@1239|Firmicutes,4IKNF@91061|Bacilli,1WS1S@1305|Streptococcus sanguinis 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01114 1046629.Ssal_02044 7.6e-113 324.0 COG1595@1|root,COG1595@2|Bacteria 2|Bacteria K DNA-templated transcription, initiation sigH - - ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 - - - ko00000,ko00001,ko03000,ko03021 - - - Sigma70_r2,Sigma70_r4_2 NFINBLID_01115 1046629.Ssal_02043 1.26e-173 486.0 COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,4HCB8@91061|Bacilli 91061|Bacilli M mechanosensitive ion channel ykuT GO:0003674,GO:0005215,GO:0006810,GO:0006950,GO:0006970,GO:0008150,GO:0008381,GO:0009628,GO:0009987,GO:0015267,GO:0022803,GO:0022836,GO:0022857,GO:0033554,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071214,GO:0071470,GO:0104004 - ko:K16052,ko:K22044 - - - - ko00000,ko02000 1.A.23.3,1.A.23.4 - - MS_channel NFINBLID_01116 1046629.Ssal_02041 3.66e-292 799.0 COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,4H9Q8@91061|Bacilli 91061|Bacilli D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase tig GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03545 - - - - ko00000 - - - FKBP_C,Trigger_C,Trigger_N NFINBLID_01117 1046629.Ssal_02039 1.24e-101 298.0 COG3343@1|root,COG3343@2|Bacteria,1V6WX@1239|Firmicutes,4HIUK@91061|Bacilli 91061|Bacilli K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling rpoE - - ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 - - - HARE-HTH NFINBLID_01118 1046629.Ssal_02036 0.0 1060.0 COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,4H9X6@91061|Bacilli 91061|Bacilli F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates pyrG - 6.3.4.2 ko:K01937 ko00240,ko01100,map00240,map01100 M00052 R00571,R00573 RC00010,RC00074 ko00000,ko00001,ko00002,ko01000 - - - CTP_synth_N,GATase NFINBLID_01119 1046629.Ssal_02035 2.5e-109 314.0 2E0MY@1|root,32W75@2|Bacteria,1VFZQ@1239|Firmicutes,4HKWR@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3013) XK27_03960 - - - - - - - - - - - DUF3013 NFINBLID_01120 904306.HMPREF9192_0255 2.26e-99 288.0 COG0494@1|root,COG0494@2|Bacteria,1V8D5@1239|Firmicutes,4HJKW@91061|Bacilli 91061|Bacilli L NUDIX domain - - 3.6.1.55 ko:K03574 - - - - ko00000,ko01000,ko03400 - - - NUDIX NFINBLID_01121 1046629.Ssal_02032 2.88e-222 613.0 COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,4HAMF@91061|Bacilli 91061|Bacilli J Ribosomal protein L11 methyltransferase prmA - - ko:K02687 - - - - ko00000,ko01000,ko03009 - - - PrmA NFINBLID_01122 1046629.Ssal_02031 9.29e-168 469.0 COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,4HH8P@91061|Bacilli 91061|Bacilli J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit rsmE GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 ko:K09761 - - - - ko00000,ko01000,ko03009 - - - Methyltrans_RNA NFINBLID_01123 1046629.Ssal_02030 0.0 1484.0 COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,4HB9S@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family cpdB - 3.1.3.6,3.1.4.16 ko:K01119 ko00230,ko00240,map00230,map00240 - R01562,R01877,R02148,R02370,R03537,R03538,R03929,R05135 RC00078,RC00296 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Gram_pos_anchor,Metallophos,SLH NFINBLID_01124 1046629.Ssal_02029 6.05e-109 313.0 COG1780@1|root,COG1780@2|Bacteria,1V71V@1239|Firmicutes,4HIW7@91061|Bacilli 91061|Bacilli F Belongs to the NrdI family nrdI - - ko:K03647 - - - - ko00000 - - - Flavodoxin_NdrI NFINBLID_01125 1046629.Ssal_02028 0.0 1446.0 COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,4HBX7@91061|Bacilli 91061|Bacilli KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance relA GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - iYO844.BSU27600 ACT_4,HD_4,RelA_SpoT,TGS NFINBLID_01126 1046629.Ssal_02026 1.08e-92 271.0 COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,4HINN@91061|Bacilli 91061|Bacilli J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality dtd GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - ko:K07560 - - - - ko00000,ko01000,ko03016 - - - Tyr_Deacylase NFINBLID_01127 1046629.Ssal_02025 0.0 1857.0 COG5297@1|root,COG5297@2|Bacteria,1TS2G@1239|Firmicutes,4HF5J@91061|Bacilli 91061|Bacilli G Glycosyl hydrolase family 66 dex - 3.2.1.11 ko:K05988 ko00500,map00500 - R11309 - ko00000,ko00001,ko01000 - GH66 - CBM_35,Glyco_hydro_66,Gram_pos_anchor,SLH NFINBLID_01128 1046629.Ssal_02023 3.18e-301 821.0 COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,4H9NK@91061|Bacilli 91061|Bacilli E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA ilvA GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 M00570 R00220,R00996 RC00418,RC02600 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_dehydrat_C NFINBLID_01129 904306.HMPREF9192_0243 5.97e-145 408.0 COG0242@1|root,COG0242@2|Bacteria,1V5C6@1239|Firmicutes,4HGUI@91061|Bacilli 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions def GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase NFINBLID_01130 1046629.Ssal_02021 1.27e-134 383.0 COG0664@1|root,COG0664@2|Bacteria,1V2AH@1239|Firmicutes,4HFNC@91061|Bacilli 91061|Bacilli K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - - - - - - - - - - HTH_Crp_2,cNMP_binding NFINBLID_01131 1046629.Ssal_02020 3.49e-228 634.0 COG2807@1|root,COG2807@2|Bacteria,1TSM5@1239|Firmicutes,4HF98@91061|Bacilli 91061|Bacilli P Major Facilitator XK27_00055 - - - - - - - - - - - MFS_1 NFINBLID_01132 435842.HMPREF0848_01487 1.74e-57 178.0 COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,4HKE9@91061|Bacilli 91061|Bacilli J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome rpsO GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02956 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S15 NFINBLID_01133 1046629.Ssal_02018 1.19e-122 351.0 COG4767@1|root,COG4767@2|Bacteria,1VM0K@1239|Firmicutes,4HVBZ@91061|Bacilli 91061|Bacilli V VanZ like family - - - - - - - - - - - - VanZ NFINBLID_01134 1046629.Ssal_02017 0.0 944.0 COG1196@1|root,COG1196@2|Bacteria,1VXI0@1239|Firmicutes,4HMHC@91061|Bacilli 91061|Bacilli D nuclear chromosome segregation - - - - - - - - - - - - Gram_pos_anchor NFINBLID_01135 904306.HMPREF9192_0239 4.26e-168 470.0 COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,4H9WY@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - - ko:K17076 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3.20 - - ABC_tran NFINBLID_01136 1046629.Ssal_02015 0.0 956.0 COG0765@1|root,COG0834@1|root,COG0765@2|Bacteria,COG0834@2|Bacteria,1TPM3@1239|Firmicutes,4HAS2@91061|Bacilli 91061|Bacilli P ABC transporter XK27_05795 - - ko:K17073,ko:K17074 ko02010,map02010 M00589 - - ko00000,ko00001,ko00002,ko02000 3.A.1.3.20 - - BPD_transp_1,SBP_bac_3 NFINBLID_01137 1046629.Ssal_02014 7.14e-195 541.0 COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,4HB0M@91061|Bacilli 91061|Bacilli V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin uppP - 3.6.1.27 ko:K06153 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - BacA NFINBLID_01139 1046629.Ssal_02012 3.47e-164 461.0 COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,4HID6@91061|Bacilli 91061|Bacilli NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis mecA GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - ko:K16511 - - - - ko00000 - - - MecA NFINBLID_01140 1046629.Ssal_02011 3.65e-241 667.0 COG0472@1|root,COG0472@2|Bacteria,1TP9V@1239|Firmicutes,4H9KT@91061|Bacilli 91061|Bacilli M transferase tagO GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 ko:K02851 - - R08856 RC00002 ko00000,ko01000,ko01003,ko01005 - - - Glycos_transf_4 NFINBLID_01141 1046629.Ssal_02010 1.65e-176 493.0 COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,4HAD9@91061|Bacilli 91061|Bacilli O ABC-type transport system involved in Fe-S cluster assembly, ATPase component sufC - - ko:K09013 - - - - ko00000,ko02000 - - - ABC_tran NFINBLID_01142 904306.HMPREF9192_0233 1.98e-297 812.0 COG0719@1|root,COG0719@2|Bacteria,1TRT0@1239|Firmicutes,4HB6W@91061|Bacilli 91061|Bacilli O assembly protein SufD sufD - - ko:K07033,ko:K09015 - - - - ko00000 - - - UPF0051 NFINBLID_01143 1046629.Ssal_02008 1.23e-295 806.0 COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,4HA6Z@91061|Bacilli 91061|Bacilli E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine sufS - 2.8.1.7,4.4.1.16 ko:K11717 ko00450,ko01100,map00450,map01100 - R03599,R11528 RC00961,RC01789,RC02313 ko00000,ko00001,ko01000 - - - Aminotran_5 NFINBLID_01144 904306.HMPREF9192_0231 7.11e-96 279.0 COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,4HIJ0@91061|Bacilli 91061|Bacilli C SUF system FeS assembly protein, NifU family nifU GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - ko:K04488 - - - - ko00000 - - - NifU_N NFINBLID_01145 904306.HMPREF9192_0230 0.0 945.0 COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,4HA1Z@91061|Bacilli 91061|Bacilli O assembly protein SufB sufB - - ko:K07033,ko:K09014 - - - - ko00000 - - - UPF0051 NFINBLID_01146 1123311.KB904471_gene1168 6.12e-35 123.0 2DCPN@1|root,2ZEV1@2|Bacteria,1W24H@1239|Firmicutes,4HZKX@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01147 1046629.Ssal_01995 7.78e-201 556.0 COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,4HAFR@91061|Bacilli 91061|Bacilli O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress hslO - - ko:K04083 - - - - ko00000,ko03110 - - - HSP33 NFINBLID_01148 435842.HMPREF0848_01508 2.41e-233 643.0 COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,4HA9K@91061|Bacilli 91061|Bacilli J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines dus - - ko:K05540 - - - - ko00000,ko01000,ko03016 - - - Dus NFINBLID_01149 1046629.Ssal_01993 2.13e-93 273.0 COG1846@1|root,COG1846@2|Bacteria,1VXZT@1239|Firmicutes,4HXMU@91061|Bacilli 91061|Bacilli K transcriptional adcR - - - - - - - - - - - HTH_27,MarR NFINBLID_01150 904306.HMPREF9192_0224 8.41e-174 484.0 COG1121@1|root,COG1121@2|Bacteria,1TQ68@1239|Firmicutes,4HAZI@91061|Bacilli 91061|Bacilli P ABC transporter, ATP-binding protein adcC - - ko:K02074,ko:K09817 ko02010,map02010 M00242,M00244 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.15,3.A.1.15.3,3.A.1.15.5 - iYO844.BSU02860 ABC_tran NFINBLID_01151 904306.HMPREF9192_0223 3.65e-165 465.0 COG1108@1|root,COG1108@2|Bacteria,1TR79@1239|Firmicutes,4HC3C@91061|Bacilli 91061|Bacilli P ABC transporter (Permease adcB GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - ko:K09816 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ABC-3 NFINBLID_01152 1046629.Ssal_01990 3.69e-203 565.0 COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,4HB48@91061|Bacilli 91061|Bacilli S Transporter, auxin efflux carrier (AEC) family protein mleP2 - - ko:K07088 - - - - ko00000 - - - Mem_trans NFINBLID_01153 1046629.Ssal_01989 0.0 1362.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,4HA8X@91061|Bacilli 91061|Bacilli G pts system ptsG - 2.7.1.208 ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 M00265,M00266,M00268,M00270,M00272,M00303,M00806 R02738,R02780,R04111,R04394,R05132,R08559 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.1.1,4.A.1.1.11,4.A.1.1.12 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NFINBLID_01154 1046629.Ssal_01988 1.79e-196 545.0 COG3568@1|root,COG3568@2|Bacteria,1TQZG@1239|Firmicutes,4HGS5@91061|Bacilli 91061|Bacilli L Endonuclease/Exonuclease/phosphatase family rgfB - 3.1.3.90 ko:K06896 ko00500,map00500 - R10486 RC00017 ko00000,ko00001,ko01000 - - - Exo_endo_phos NFINBLID_01155 469609.HMPREF0847_00157 0.0 877.0 COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,4H9VI@91061|Bacilli 91061|Bacilli G Belongs to the GPI family pgi GO:0003674,GO:0003824,GO:0004347,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 M00001,M00004,M00114 R02739,R02740,R03321 RC00376,RC00563 ko00000,ko00001,ko00002,ko01000,ko04147 - - - PGI NFINBLID_01156 888821.HMPREF9394_0309 4.62e-182 507.0 COG1028@1|root,COG1028@2|Bacteria,1TP2V@1239|Firmicutes,4HCAG@91061|Bacilli 91061|Bacilli IQ Belongs to the short-chain dehydrogenases reductases (SDR) family sorD - 1.1.1.140 ko:K00068 ko00051,map00051 - R05607 RC00085 ko00000,ko00001,ko01000 - - - adh_short NFINBLID_01157 1419814.V470_00715 0.0 1150.0 COG1762@1|root,COG3711@1|root,COG1762@2|Bacteria,COG3711@2|Bacteria,1UZ36@1239|Firmicutes,4HDUK@91061|Bacilli 91061|Bacilli GKT Mga helix-turn-helix domain srlM - - ko:K03491 - - - - ko00000,ko03000 - - - HTH_11,Mga,PRD,PTS_EIIA_2 NFINBLID_01158 888821.HMPREF9394_0311 2.45e-109 315.0 COG4578@1|root,COG4578@2|Bacteria 2|Bacteria K phosphoenolpyruvate-dependent sugar phosphotransferase system gutM GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02466 - - - - ko00000 - - - GutM NFINBLID_01159 1297534.CAUJ01000005_gene14 6.32e-124 353.0 COG3730@1|root,COG3730@2|Bacteria,1URER@1239|Firmicutes,4HEHX@91061|Bacilli 91061|Bacilli G PTS system glucitol sorbitol-specific srlA - - ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.4.1 - - EII-GUT NFINBLID_01160 469609.HMPREF0847_00162 4.63e-228 629.0 COG3732@1|root,COG3732@2|Bacteria,1TQ8F@1239|Firmicutes,4HA7E@91061|Bacilli 91061|Bacilli G PTS sorbitol transporter subunit IIB srlE - 2.7.1.198 ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - EIIBC-GUT_C,EIIBC-GUT_N NFINBLID_01161 888821.HMPREF9394_0314 1.28e-77 231.0 COG3731@1|root,COG3731@2|Bacteria,1VG8V@1239|Firmicutes,4HMEK@91061|Bacilli 91061|Bacilli G sorbitol-specific, IIA component srlB - 2.7.1.198 ko:K02781 ko00051,ko02060,map00051,map02060 M00280 R05820 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.4.1 - - PTSIIA_gutA NFINBLID_01162 862967.SIR_1562 2.58e-77 233.0 COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,4HAXJ@91061|Bacilli,42E7F@671232|Streptococcus anginosus group 91061|Bacilli L MULE transposase domain B4168_4126 - - ko:K07493 - - - - ko00000 - - - Transposase_mut NFINBLID_01163 904294.HMPREF9182_1249 6.62e-138 399.0 COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,4IPIE@91061|Bacilli 91061|Bacilli L Transposase IS116 IS110 IS902 - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 NFINBLID_01164 1123300.AUIN01000009_gene132 0.0 1048.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS NFINBLID_01165 904306.HMPREF9192_0472 2.42e-281 771.0 COG3464@1|root,COG3464@2|Bacteria,1VQIX@1239|Firmicutes 1239|Firmicutes L the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3 NFINBLID_01166 1046629.Ssal_01986 8.7e-199 551.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding Z012_04635 - - ko:K20373 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_3,HTH_31 NFINBLID_01167 1046629.Ssal_01985 0.0 957.0 COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,4HCIZ@91061|Bacilli 91061|Bacilli V ABC transporter - - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NFINBLID_01168 1046629.Ssal_01984 2.37e-161 452.0 COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,4H9WJ@91061|Bacilli 91061|Bacilli K transcriptional regulatory protein yeeN GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - - - - - - - - - - Transcrip_reg NFINBLID_01169 904306.HMPREF9192_0217 4.95e-61 189.0 COG1862@1|root,COG1862@2|Bacteria 2|Bacteria U protein transport yajC GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - YajC NFINBLID_01170 1046629.Ssal_01982 2.31e-178 496.0 COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,4HA37@91061|Bacilli 91061|Bacilli H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids uppS GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 ko:K00806 ko00900,ko01110,map00900,map01110 - R06447 RC00279,RC02839 ko00000,ko00001,ko01000,ko01006 - - - Prenyltransf NFINBLID_01171 1046629.Ssal_01981 4.82e-183 509.0 COG4589@1|root,COG4589@2|Bacteria,1TT0Q@1239|Firmicutes,4HAMN@91061|Bacilli 91061|Bacilli S Belongs to the CDS family cdsA GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 M00093 R01799 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06255 CTP_transf_1 NFINBLID_01172 1046629.Ssal_01980 3.83e-295 806.0 COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,4HAQ5@91061|Bacilli 91061|Bacilli M zinc metalloprotease rseP - - ko:K11749 ko02024,ko04112,map02024,map04112 - - - ko00000,ko00001,ko01000,ko01002 - - - PDZ_2,Peptidase_M50 NFINBLID_01173 1046629.Ssal_01979 0.0 1192.0 COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,4H9NN@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS proS - 6.1.1.15 ko:K01881 ko00970,map00970 M00359,M00360 R03661 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_2b,tRNA_edit NFINBLID_01174 1046629.Ssal_01978 0.0 1148.0 COG2984@1|root,COG4120@1|root,COG2984@2|Bacteria,COG4120@2|Bacteria,1TPB0@1239|Firmicutes,4HESK@91061|Bacilli 91061|Bacilli S ABC transporter XK27_00665 - - ko:K01989,ko:K05832 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_sub_bind NFINBLID_01175 1046629.Ssal_01977 8.63e-183 509.0 COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,4HCHC@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein cmpC - - ko:K05833 - M00247 - - ko00000,ko00002,ko02000 - - - ABC_tran NFINBLID_01176 1046629.Ssal_01975 7.72e-57 177.0 COG0234@1|root,COG0234@2|Bacteria 2|Bacteria O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter groS GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0032991,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:0101031,GO:1903506,GO:1990220,GO:2000112,GO:2001141 - ko:K04078 - - - - ko00000,ko03029,ko03110 - - - Cpn10 NFINBLID_01177 1046629.Ssal_01974 0.0 983.0 COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,4HA38@91061|Bacilli 91061|Bacilli O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions groL GO:0001817,GO:0001819,GO:0001871,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009986,GO:0009987,GO:0016465,GO:0030246,GO:0030247,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044764,GO:0046812,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051082,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051704,GO:0061077,GO:0065007,GO:0070201,GO:0090087,GO:0098630,GO:0098743,GO:0101031,GO:1903530,GO:1903532,GO:1904951,GO:1990220,GO:2000482,GO:2000484,GO:2001065 - ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 - - - Cpn60_TCP1 NFINBLID_01179 435842.HMPREF0848_01529 5.73e-58 180.0 2C0H5@1|root,2ZRTJ@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - DUF2752 NFINBLID_01180 904306.HMPREF9192_0207 5.41e-73 219.0 COG2314@1|root,COG2314@2|Bacteria,1VKEZ@1239|Firmicutes,4HS74@91061|Bacilli 91061|Bacilli S TM2 domain WQ51_06355 - - - - - - - - - - - TM2 NFINBLID_01181 1046629.Ssal_01970 8.17e-208 574.0 COG0564@1|root,COG0564@2|Bacteria,1TSM6@1239|Firmicutes,4HA7M@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluA GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 ko:K06177,ko:K06180 - - - - ko00000,ko01000,ko03009,ko03016 - - - PseudoU_synth_2 NFINBLID_01182 904306.HMPREF9192_0205 0.0 1484.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli 91061|Bacilli M penicillin-binding protein pbp2A - 2.4.1.129,3.4.16.4 ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase NFINBLID_01183 936154.STP_1748 5.51e-28 100.0 COG0267@1|root,COG0267@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG - - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 NFINBLID_01184 904306.HMPREF9192_0204 1.05e-33 115.0 COG0690@1|root,COG0690@2|Bacteria,1W4QH@1239|Firmicutes 1239|Firmicutes U Belongs to the SecE SEC61-gamma family secE - - ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.2 - - SecE NFINBLID_01185 1046629.Ssal_01967 2.8e-124 354.0 COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,4HAJA@91061|Bacilli 91061|Bacilli K Participates in transcription elongation, termination and antitermination nusG GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02601 - - - - ko00000,ko03009,ko03021 - - - KOW,NusG NFINBLID_01186 264199.stu0216 1.91e-93 275.0 COG0671@1|root,COG0671@2|Bacteria 2|Bacteria I phosphatidate phosphatase activity - - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 - R02029,R05627 RC00002,RC00017 ko00000,ko00001,ko01000,ko01011 - - - PAP2 NFINBLID_01187 904306.HMPREF9192_0201 4.46e-186 518.0 COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,4HK1G@91061|Bacilli 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase cof - - - - - - - - - - - Hydrolase_3 NFINBLID_01188 1046629.Ssal_01963 2.09e-168 472.0 COG1349@1|root,COG1349@2|Bacteria,1V6VV@1239|Firmicutes,4HK1E@91061|Bacilli 91061|Bacilli K transcriptional regulator (DeoR family) - - - ko:K22103 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR NFINBLID_01189 435842.HMPREF0848_01539 0.0 1692.0 COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,4HAG1@91061|Bacilli 91061|Bacilli J Belongs to the class-I aminoacyl-tRNA synthetase family leuS GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 ko:K01869 ko00970,map00970 M00359,M00360 R03657 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - Anticodon_1,tRNA-synt_1,tRNA-synt_1_2 NFINBLID_01190 1095726.HMPREF1116_1199 3.18e-96 281.0 COG1846@1|root,COG1846@2|Bacteria,1VD5S@1239|Firmicutes,4HMXZ@91061|Bacilli 91061|Bacilli K helix_turn_helix multiple antibiotic resistance protein - - - - - - - - - - - - MarR NFINBLID_01191 904306.HMPREF9192_0197 2.74e-279 766.0 COG1073@1|root,COG1073@2|Bacteria,1V38K@1239|Firmicutes,4HE7V@91061|Bacilli 91061|Bacilli S COG1073 Hydrolases of the alpha beta superfamily - - - ko:K06889 - - - - ko00000 - - - BAAT_C,Bile_Hydr_Trans NFINBLID_01192 1046629.Ssal_01957 1.61e-193 538.0 COG1131@1|root,COG1131@2|Bacteria,1V0AH@1239|Firmicutes,4HD15@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein cylA - - ko:K11050 ko02010,map02010 M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1.130 - - ABC_tran NFINBLID_01193 999425.HMPREF9186_01407 1.09e-171 482.0 COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,4HFNX@91061|Bacilli 91061|Bacilli V ABC-2 type transporter cylB - - ko:K11051 ko02010,map02010 M00298 - - ko00000,ko00001,ko00002,ko02000 3.A.1.130 - - ABC2_membrane,ABC2_membrane_3 NFINBLID_01194 1046629.Ssal_01955 9.49e-98 285.0 COG3279@1|root,COG3279@2|Bacteria,1VFKH@1239|Firmicutes,4HQ50@91061|Bacilli 91061|Bacilli K COG3279 Response regulator of the LytR AlgR family - - - ko:K07705 ko02020,map02020 M00492 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR NFINBLID_01195 585203.SMSK564_0811 3.6e-42 143.0 2DKBP@1|root,30949@2|Bacteria,1U4EH@1239|Firmicutes,4IE74@91061|Bacilli,2TPSA@28037|Streptococcus mitis 91061|Bacilli S Protein of unknown function (DUF3021) - - - - - - - - - - - - DUF3021 NFINBLID_01196 435842.HMPREF0848_01547 2.38e-160 450.0 COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,4HCVW@91061|Bacilli 91061|Bacilli K Transcriptional mta - - ko:K21743 - - - - ko00000,ko03000 - - - MerR_1,TipAS NFINBLID_01197 1046629.Ssal_01952 1.82e-155 437.0 COG1136@1|root,COG1136@2|Bacteria,1V50G@1239|Firmicutes,4HIB8@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - - - - - - - - - - ABC_tran NFINBLID_01198 1046629.Ssal_01951 4.33e-259 714.0 COG0577@1|root,COG0577@2|Bacteria,1VU6Y@1239|Firmicutes,4HT9M@91061|Bacilli 91061|Bacilli V FtsX-like permease family - - - - - - - - - - - - FtsX NFINBLID_01199 1046629.Ssal_01950 0.0 951.0 COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,4HAI4@91061|Bacilli 91061|Bacilli H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP pncB - 6.3.4.21 ko:K00763 ko00760,ko01100,map00760,map01100 - R01724 RC00033 ko00000,ko00001,ko01000 - - - NAPRTase NFINBLID_01200 904306.HMPREF9192_0172 6.61e-190 528.0 COG0171@1|root,COG0171@2|Bacteria,1TQ38@1239|Firmicutes,4HA2R@91061|Bacilli 91061|Bacilli H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source nadE GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 ko:K01916 ko00760,ko01100,map00760,map01100 M00115 R00189 RC00100 ko00000,ko00001,ko00002,ko01000 - - - NAD_synthase NFINBLID_01201 1046629.Ssal_01947 4.75e-96 280.0 COG3152@1|root,COG3152@2|Bacteria,1VDSW@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF805) yhaH - - - - - - - - - - - DUF805 NFINBLID_01202 1046629.Ssal_01946 0.0 880.0 COG3579@1|root,COG3579@2|Bacteria,1TRJN@1239|Firmicutes,4HBZ9@91061|Bacilli 91061|Bacilli E aminopeptidase pepC GO:0000096,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006508,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0009056,GO:0009063,GO:0009636,GO:0009987,GO:0016054,GO:0016787,GO:0019538,GO:0019752,GO:0042221,GO:0043170,GO:0043418,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0050667,GO:0050896,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.4.22.40 ko:K01372 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C1_2 NFINBLID_01203 1046629.Ssal_01944 0.0 1392.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli 91061|Bacilli M penicillin-binding protein ponA GO:0005575,GO:0005576 2.4.1.129,3.4.16.4 ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase,fn3 NFINBLID_01204 1046629.Ssal_01943 1.72e-141 399.0 COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,4HGZ7@91061|Bacilli 91061|Bacilli L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation recU GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - ko:K03700 - - - - ko00000,ko03400 - - - RecU NFINBLID_01205 1046629.Ssal_01942 6.97e-121 345.0 COG4474@1|root,COG4474@2|Bacteria,1V5Q7@1239|Firmicutes,4HECZ@91061|Bacilli 91061|Bacilli S Belongs to the UPF0398 family ypsA - - - - - - - - - - - DUF1273 NFINBLID_01206 1046629.Ssal_01941 8.01e-66 201.0 COG3599@1|root,COG3599@2|Bacteria,1VEQ4@1239|Firmicutes,4HNP1@91061|Bacilli 91061|Bacilli D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation gpsB - - - - - - - - - - - DivIVA NFINBLID_01207 1046629.Ssal_01940 4.34e-283 773.0 COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,4HBKY@91061|Bacilli 91061|Bacilli L Belongs to the methyltransferase superfamily ypsC GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - ko:K07444 - - - - ko00000,ko01000 - - - THUMP,UPF0020 NFINBLID_01208 1046629.Ssal_01939 0.0 1063.0 2DB6P@1|root,32TWV@2|Bacteria,1VDPS@1239|Firmicutes,4HK8Y@91061|Bacilli 91061|Bacilli D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning mapZ - - ko:K20073 - - - - ko00000 - - - - NFINBLID_01209 1046629.Ssal_01938 0.0 1999.0 COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,4HAIF@91061|Bacilli 91061|Bacilli L Superfamily II DNA RNA helicases, SNF2 family' snf - - - - - - - - - - - Helicase_C,SNF2_N,SNF2_assoc,SWIM NFINBLID_01210 1214166.ALLG01000002_gene1746 4.8e-28 113.0 2BTGZ@1|root,32NPB@2|Bacteria,1U91J@1239|Firmicutes,4IJ1N@91061|Bacilli,1WTEE@1307|Streptococcus suis 91061|Bacilli - - XK27_11680 - - - - - - - - - - - - NFINBLID_01211 1046629.Ssal_01936 0.0 881.0 COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,4HAR4@91061|Bacilli 91061|Bacilli M Belongs to the MurCDEF family murC - 6.3.2.8 ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 - R03193 RC00064,RC00141 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase,Mur_ligase_C,Mur_ligase_M NFINBLID_01212 1046629.Ssal_01935 1.42e-112 323.0 COG0454@1|root,COG0454@2|Bacteria,1VB76@1239|Firmicutes,4HM71@91061|Bacilli 91061|Bacilli K histone acetyltransferase HPA2 and related acetyltransferases - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10 NFINBLID_01213 1046629.Ssal_01934 0.0 1149.0 COG1559@1|root,COG1559@2|Bacteria,1TS48@1239|Firmicutes,4HAUV@91061|Bacilli 91061|Bacilli ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation mltG - - ko:K07082 - - - - ko00000 - - - YceG NFINBLID_01214 1046629.Ssal_01933 1.17e-100 293.0 COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,4HGZU@91061|Bacilli 91061|Bacilli K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides greA GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - ko:K03624 - - - - ko00000,ko03021 - - - GreA_GreB,GreA_GreB_N NFINBLID_01215 1046629.Ssal_01931 9.19e-213 588.0 COG0706@1|root,COG0706@2|Bacteria,1TSDN@1239|Firmicutes,4HCC8@91061|Bacilli 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC - - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP NFINBLID_01216 1046629.Ssal_01930 2.63e-58 180.0 COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,4HNN7@91061|Bacilli 91061|Bacilli C Belongs to the acylphosphatase family acyP GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 - R00317,R01421,R01515 RC00043 ko00000,ko00001,ko01000 - - iSB619.SA_RS07020 Acylphosphatase NFINBLID_01217 1046629.Ssal_01929 3.11e-165 463.0 COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,4HCF5@91061|Bacilli 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family spoU - - ko:K03437 - - - - ko00000,ko03016 - - - SpoU_methylase,SpoU_sub_bind NFINBLID_01218 1046629.Ssal_01928 2.55e-121 345.0 COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,4HHW0@91061|Bacilli 91061|Bacilli S HD superfamily hydrolase XK27_09705 - - ko:K06950 - - - - ko00000 - - - HD NFINBLID_01219 1046629.Ssal_01927 2e-144 409.0 COG0670@1|root,COG0670@2|Bacteria,1V779@1239|Firmicutes,4HIX1@91061|Bacilli 91061|Bacilli S Belongs to the BI1 family ybhL - - ko:K06890 - - - - ko00000 - - - Bax1-I NFINBLID_01221 1046629.Ssal_01925 4.75e-309 841.0 COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,4H9XW@91061|Bacilli 91061|Bacilli E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine lysA - 4.1.1.20 ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R00451 RC00299 ko00000,ko00001,ko00002,ko01000 - - - Orn_Arg_deC_N,Orn_DAP_Arg_deC NFINBLID_01222 1046629.Ssal_01924 2.11e-115 332.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator - - - - - - - - - - - - TetR_N NFINBLID_01223 1046629.Ssal_01923 2.31e-48 154.0 COG3763@1|root,COG3763@2|Bacteria,1VDSU@1239|Firmicutes,4HM8G@91061|Bacilli 91061|Bacilli S UPF0154 protein - - - ko:K09976 - - - - ko00000 - - - UPF0154 NFINBLID_01224 1046629.Ssal_01922 1.14e-189 527.0 COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,4HA46@91061|Bacilli 91061|Bacilli M Provides the (R)-glutamate required for cell wall biosynthesis murI GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.6.1.66,5.1.1.3 ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 - R00260,R00426,R00720,R01855,R02100,R02720,R03531 RC00002,RC00302 ko00000,ko00001,ko01000,ko01011 - - iYO844.BSU28390 Asp_Glu_race NFINBLID_01225 1046629.Ssal_01921 7.16e-231 635.0 COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,4HCP6@91061|Bacilli 91061|Bacilli F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions rdgB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 ko:K02428 ko00230,map00230 - R00426,R00720,R01855,R02100,R02720,R03531 RC00002 ko00000,ko00001,ko01000 - - - Ham1p_like NFINBLID_01226 904306.HMPREF9192_0139 3.44e-122 348.0 COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,4HM24@91061|Bacilli 91061|Bacilli S Phosphoesterase ysnB GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - ko:K07095 - - - - ko00000 - - - Metallophos_2 NFINBLID_01227 1046629.Ssal_01919 5e-111 319.0 COG0517@1|root,COG0517@2|Bacteria,1VFAB@1239|Firmicutes,4HRWJ@91061|Bacilli 91061|Bacilli S CBS domain ykuL - - - - - - - - - - - CBS NFINBLID_01228 1046629.Ssal_01918 3.21e-163 459.0 COG4974@1|root,COG4974@2|Bacteria,1VY7C@1239|Firmicutes,4IT0W@91061|Bacilli 91061|Bacilli L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site xerD - - - - - - - - - - - Phage_int_SAM_1,Phage_integrase NFINBLID_01229 904306.HMPREF9192_0136 2.26e-154 435.0 COG1354@1|root,COG1354@2|Bacteria,1V8JV@1239|Firmicutes,4IQZ5@91061|Bacilli 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves scpA - - ko:K05896 - - - - ko00000,ko03036 - - - SMC_ScpA NFINBLID_01230 904306.HMPREF9192_0135 8.12e-124 354.0 COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,4HIQ0@91061|Bacilli 91061|Bacilli D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves scpB GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K06024 - - - - ko00000,ko03036 - - - SMC_ScpB NFINBLID_01231 1046629.Ssal_01915 1.23e-169 474.0 COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,4H9MU@91061|Bacilli 91061|Bacilli J Belongs to the pseudouridine synthase RsuA family rluB - 5.4.99.22 ko:K06178 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 NFINBLID_01232 435842.HMPREF0848_01585 4.11e-53 166.0 COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,4HPA3@91061|Bacilli 91061|Bacilli S Could be involved in insertion of integral membrane proteins into the membrane ytjA - - ko:K08998 - - - - ko00000 - - - Haemolytic NFINBLID_01233 1046629.Ssal_01912 0.0 896.0 COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,4HCWN@91061|Bacilli 91061|Bacilli P Cation transport protein trkH - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH NFINBLID_01234 1046629.Ssal_01911 5.21e-310 846.0 COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,4HCRM@91061|Bacilli 91061|Bacilli P Potassium transporter peripheral membrane component trkA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N NFINBLID_01235 1046629.Ssal_01910 6.48e-125 355.0 COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,4HFNY@91061|Bacilli 91061|Bacilli J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily cspR - 2.1.1.207 ko:K03216 - - - - ko00000,ko01000,ko03016 - - - SpoU_methylase NFINBLID_01236 264199.stu0268 3.96e-117 337.0 COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,4HHFT@91061|Bacilli 91061|Bacilli U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins ribU GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - - - - - - - - - - ECF_trnsprt NFINBLID_01237 264199.stu0269 5.04e-127 364.0 COG0671@1|root,COG0671@2|Bacteria,1VF2U@1239|Firmicutes,4HNXR@91061|Bacilli 91061|Bacilli I Membrane-associated phospholipid phosphatase yodM - 3.6.1.27 ko:K19302 ko00550,map00550 - R05627 RC00002 ko00000,ko00001,ko01000,ko01011 - - - PAP2 NFINBLID_01238 264199.stu0270 1.01e-197 550.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K20342,ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_19,HTH_3 NFINBLID_01239 1046629.Ssal_01906 0.0 1281.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA - - ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 - - - ko00000,ko00001,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.112,3.A.1.21 - - ABC_membrane,ABC_tran,Peptidase_C39 NFINBLID_01240 904306.HMPREF9192_0123 2.12e-70 212.0 COG3152@1|root,COG3152@2|Bacteria 2|Bacteria L Membrane yhaI - - - - - - - - - - - DUF805 NFINBLID_01241 1046629.Ssal_01904 8.21e-305 834.0 2E26M@1|root,32XD2@2|Bacteria,1VCM1@1239|Firmicutes 1239|Firmicutes S Domain of unknown function (DUF4173) - - - - - - - - - - - - DUF4173 NFINBLID_01242 1046629.Ssal_01903 3.59e-123 350.0 2DC0F@1|root,2ZC7C@2|Bacteria,1UPV2@1239|Firmicutes,4IVBC@91061|Bacilli 91061|Bacilli S AmiS/UreI family transporter ureI - - ko:K03191 ko05120,map05120 - - - ko00000,ko00001,ko02000 1.A.29.1.3,1.A.29.1.4,1.A.29.1.5 - - AmiS_UreI NFINBLID_01243 264199.stu0281 1.02e-61 189.0 COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,4HIJS@91061|Bacilli 91061|Bacilli E Belongs to the urease gamma subunit family ureA - 3.5.1.5 ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - iSB619.SA_RS11965,iYO844.BSU36660 Urease_gamma NFINBLID_01244 1046629.Ssal_01901 8.93e-71 213.0 COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,4HM0I@91061|Bacilli 91061|Bacilli E Belongs to the urease beta subunit family ureB - 3.5.1.5 ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Urease_beta NFINBLID_01245 904306.HMPREF9192_0116 0.0 1155.0 COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,4HBTS@91061|Bacilli 91061|Bacilli E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family ureC - 3.5.1.5 ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 - R00131 RC02798,RC02806 ko00000,ko00001,ko01000 - - - Amidohydro_1,Urease_alpha NFINBLID_01246 1046629.Ssal_01898 2.74e-101 293.0 COG2371@1|root,COG2371@2|Bacteria 2|Bacteria O enzyme active site formation ureE GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K03187 - - - - ko00000 - - - UreE_C,UreE_N NFINBLID_01247 1046629.Ssal_01897 1.23e-167 468.0 COG0830@1|root,COG0830@2|Bacteria,1V2H0@1239|Firmicutes,4HHW3@91061|Bacilli 91061|Bacilli O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureF - - ko:K03188 - - - - ko00000 - - - UreF NFINBLID_01248 1046629.Ssal_01896 4.71e-142 401.0 COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,4HC5C@91061|Bacilli 91061|Bacilli KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG ureG - - ko:K03189 - - - - ko00000 - - - cobW NFINBLID_01249 264199.stu0287 3.32e-202 559.0 COG0829@1|root,COG0829@2|Bacteria,1TVM2@1239|Firmicutes,4HCED@91061|Bacilli 91061|Bacilli O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter ureD - - ko:K03190 - - - - ko00000 - - - UreD NFINBLID_01250 1046629.Ssal_01894 4.11e-226 624.0 COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,4HARY@91061|Bacilli 91061|Bacilli P PDGLE domain cbiM - - ko:K02007 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiM,PDGLE NFINBLID_01251 1046629.Ssal_01892 6.8e-176 491.0 COG0619@1|root,COG0619@2|Bacteria,1V7YC@1239|Firmicutes 1239|Firmicutes P cobalt transport protein nikQ - - ko:K02008 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - CbiQ NFINBLID_01252 1046629.Ssal_01891 9.38e-168 469.0 COG1122@1|root,COG1122@2|Bacteria,1V16T@1239|Firmicutes,4HI15@91061|Bacilli 91061|Bacilli P ABC transporter - - - ko:K02006 ko02010,map02010 M00245,M00246 - - ko00000,ko00001,ko00002,ko02000 3.A.1.18,3.A.1.22,3.A.1.23 - - ABC_tran NFINBLID_01253 1046629.Ssal_01890 9.97e-185 515.0 COG0834@1|root,COG0834@2|Bacteria,1VWFY@1239|Firmicutes,4HW2H@91061|Bacilli 91061|Bacilli ET ABC transporter substrate-binding protein - - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 NFINBLID_01254 1046629.Ssal_01889 2e-209 579.0 COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,4HCTA@91061|Bacilli 91061|Bacilli M Belongs to the NlpA lipoprotein family metQ - - ko:K02073 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - Lipoprotein_9 NFINBLID_01255 1046629.Ssal_01888 0.0 912.0 COG0624@1|root,COG0624@2|Bacteria,1TP2D@1239|Firmicutes,4HB9G@91061|Bacilli 91061|Bacilli E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases dapE - 3.5.1.18 ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 M00016 R02734 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - M20_dimer,Peptidase_M20,Peptidase_M28 NFINBLID_01256 1046629.Ssal_01887 4.67e-238 656.0 COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,4H9VX@91061|Bacilli 91061|Bacilli P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system metN - - ko:K02071 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - ABC_tran,NIL NFINBLID_01257 1046629.Ssal_01886 1.27e-152 430.0 COG2011@1|root,COG2011@2|Bacteria,1V0GE@1239|Firmicutes,4HFMB@91061|Bacilli 91061|Bacilli P ABC transporter (Permease metI - - ko:K02072 ko02010,map02010 M00238 - - ko00000,ko00001,ko00002,ko02000 3.A.1.24 - - BPD_transp_1 NFINBLID_01258 1046629.Ssal_01885 4.9e-266 731.0 COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,4HBEC@91061|Bacilli 91061|Bacilli E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) sstT - - ko:K07862 - - - - ko00000,ko02000 2.A.23.4 - - SDF NFINBLID_01259 322159.STER_0345 1.2e-201 558.0 COG1912@1|root,COG1912@2|Bacteria,1TSR3@1239|Firmicutes,4HAW6@91061|Bacilli 91061|Bacilli S S-adenosyl-l-methionine hydroxide adenosyltransferase ilvH - - - - - - - - - - - SAM_adeno_trans NFINBLID_01260 1046629.Ssal_01883 8.98e-122 348.0 COG4720@1|root,COG4720@2|Bacteria,1V1GT@1239|Firmicutes,4HGAE@91061|Bacilli 91061|Bacilli S UPF0397 protein - - - ko:K16924 - M00582 - - ko00000,ko00002,ko02000 3.A.1.29 - - ECF-ribofla_trS NFINBLID_01261 1046629.Ssal_01882 0.0 1061.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HAJM@91061|Bacilli 91061|Bacilli P abc transporter atp-binding protein ykoD GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085 - ko:K16786,ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran,DUF3744 NFINBLID_01262 1046629.Ssal_01881 1.13e-187 522.0 COG0619@1|root,COG0619@2|Bacteria,1TPMV@1239|Firmicutes,4HBTW@91061|Bacilli 91061|Bacilli P cobalt transport cbiQ - - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iSB619.SA_RS14165 CbiQ NFINBLID_01263 1046629.Ssal_01880 3.02e-152 428.0 COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,4HBPH@91061|Bacilli 91061|Bacilli P COG0569 K transport systems, NAD-binding component ktrA - - ko:K03499 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkA_C,TrkA_N NFINBLID_01264 1046629.Ssal_01879 1.52e-295 810.0 COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,4H9ME@91061|Bacilli 91061|Bacilli P COG0168 Trk-type K transport systems, membrane components ktrB - - ko:K03498 - - - - ko00000,ko02000 2.A.38.1,2.A.38.4 - - TrkH NFINBLID_01265 1046629.Ssal_01878 1.14e-163 458.0 COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,4HAAZ@91061|Bacilli 91061|Bacilli J Ribosomal RNA small subunit methyltransferase G rsmG GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 ko:K03501 - - - - ko00000,ko01000,ko03009,ko03036 - - - GidB NFINBLID_01266 1046629.Ssal_01877 1.89e-117 337.0 COG1399@1|root,COG1399@2|Bacteria,1VB08@1239|Firmicutes,4HME9@91061|Bacilli 91061|Bacilli K metal-binding, possibly nucleic acid-binding protein ylbN - - ko:K07040 - - - - ko00000 - - - DUF177 NFINBLID_01267 435842.HMPREF0848_01620 1.62e-159 447.0 COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,4H9NE@91061|Bacilli 91061|Bacilli T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain csrR - - - - - - - - - - - Response_reg,Trans_reg_C NFINBLID_01268 435842.HMPREF0848_01621 0.0 960.0 COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,4HWKS@91061|Bacilli 91061|Bacilli T Histidine kinase covS - - - - - - - - - - - HAMP,HATPase_c,HisKA NFINBLID_01269 1046629.Ssal_01874 5.84e-105 303.0 COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,4HGXA@91061|Bacilli 91061|Bacilli K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes nrdR - - ko:K07738 - - - - ko00000,ko03000 - - - ATP-cone NFINBLID_01270 1046629.Ssal_01873 1.79e-267 734.0 COG3611@1|root,COG3611@2|Bacteria 2|Bacteria L Replication initiation and membrane attachment dnaB - - ko:K03346 - - - - ko00000,ko03032 - - - DnaB_2 NFINBLID_01271 1046629.Ssal_01872 1.47e-211 585.0 COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,4HABS@91061|Bacilli 91061|Bacilli L Primosomal protein DnaI dnaI GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K11144 - - - - ko00000,ko03032 - - - DnaI_N,IstB_IS21 NFINBLID_01272 1046629.Ssal_01871 6.87e-313 852.0 COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,4HAJ6@91061|Bacilli 91061|Bacilli S GTPase that plays an essential role in the late steps of ribosome biogenesis der - - ko:K03977 - - - - ko00000,ko03009 - - - KH_dom-like,MMR_HSR1 NFINBLID_01273 1046629.Ssal_01870 4.11e-134 381.0 2CH4S@1|root,32S58@2|Bacteria,1VC9V@1239|Firmicutes,4HNHW@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01274 1046629.Ssal_01869 4.62e-296 809.0 COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,4H9Y4@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) serS - 6.1.1.11 ko:K01875 ko00970,map00970 M00359,M00360 R03662,R08218 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Seryl_tRNA_N,tRNA-synt_2b NFINBLID_01275 904306.HMPREF9192_0083 3.08e-81 241.0 COG4687@1|root,COG4687@2|Bacteria,1VF36@1239|Firmicutes,4HPYI@91061|Bacilli 91061|Bacilli S protein conserved in bacteria manO - - - - - - - - - - - DUF956 NFINBLID_01276 1046629.Ssal_01867 5.78e-215 593.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli 91061|Bacilli G PTS system mannose fructose sorbose family IID component manN - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA NFINBLID_01277 1046629.Ssal_01866 7.94e-165 464.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli 91061|Bacilli G pts system manM - - ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277 R02630,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.4 - - EII-Sor NFINBLID_01278 1046629.Ssal_01865 1.39e-231 638.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli 91061|Bacilli G pts system manL - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - EIIA-man,PTSIIB_sorb NFINBLID_01279 1046629.Ssal_01864 4.66e-87 256.0 COG4687@1|root,COG4687@2|Bacteria,1V6KV@1239|Firmicutes 1239|Firmicutes S Protein conserved in bacteria manO - - - - - - - - - - - DUF956 NFINBLID_01280 1046629.Ssal_01863 2.24e-208 577.0 COG3716@1|root,COG3716@2|Bacteria,1TQA3@1239|Firmicutes,4HA3K@91061|Bacilli 91061|Bacilli G PTS system mannose fructose sorbose family IID component manN - - ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 M00276 R02630 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1 - - EIID-AGA NFINBLID_01281 1046629.Ssal_01862 6.45e-173 484.0 COG3715@1|root,COG3715@2|Bacteria,1TPKK@1239|Firmicutes,4H9QI@91061|Bacilli 91061|Bacilli G pts system manM - - ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 M00276,M00277 R02630,R08366 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.6.1,4.A.6.1.4 - - EII-Sor NFINBLID_01282 1046629.Ssal_01861 7.02e-223 616.0 COG2893@1|root,COG3444@1|root,COG2893@2|Bacteria,COG3444@2|Bacteria,1TQJ4@1239|Firmicutes,4H9Z8@91061|Bacilli 91061|Bacilli G pts system manX - 2.7.1.191,2.7.1.202 ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 M00273,M00276 R02630,R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1,4.A.6.1 - - EIIA-man,PTSIIB_sorb NFINBLID_01283 1046629.Ssal_01860 1.07e-173 485.0 COG1878@1|root,COG1878@2|Bacteria,1TRBQ@1239|Firmicutes,4HCAB@91061|Bacilli 91061|Bacilli S Metal-dependent hydrolase XK27_00940 - 3.5.1.9 ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 M00038 R00988,R01959,R04911 RC00263,RC00323 ko00000,ko00001,ko00002,ko01000 - - - Cyclase NFINBLID_01284 1046629.Ssal_01859 5.08e-197 545.0 COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,4H9Y9@91061|Bacilli 91061|Bacilli S hydrolases of the HAD superfamily yitU - 3.1.3.104 ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 M00125 R07280 RC00017 ko00000,ko00001,ko00002,ko01000 - - - Hydrolase_3 NFINBLID_01285 1046629.Ssal_01858 7.03e-316 863.0 COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,4HANG@91061|Bacilli 91061|Bacilli S permease XK27_07275 - - ko:K06901 - - - - ko00000,ko02000 2.A.1.40 - - Xan_ur_permease NFINBLID_01286 1046629.Ssal_01857 2.55e-100 291.0 COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,4HIIF@91061|Bacilli 91061|Bacilli M ATPase or kinase ydiB GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - ko:K06925 - - - - ko00000,ko03016 - - - TsaE NFINBLID_01287 1046629.Ssal_01856 2.24e-118 338.0 COG1247@1|root,COG1247@2|Bacteria 2|Bacteria M phosphinothricin N-acetyltransferase activity XK27_05885 - 2.3.1.82 ko:K18816 - - - - br01600,ko00000,ko01000,ko01504 - - - Acetyltransf_1 NFINBLID_01288 1046629.Ssal_01855 3.62e-248 687.0 COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,4HA09@91061|Bacilli 91061|Bacilli K Transcriptional brpA - - - - - - - - - - - LytR_cpsA_psr NFINBLID_01289 1046629.Ssal_01854 3.54e-105 304.0 COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,4HH88@91061|Bacilli 91061|Bacilli S Required for maturation of 30S ribosomal subunits rimP GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K09748 - - - - ko00000,ko03009 - - - DUF150,DUF150_C NFINBLID_01290 1046629.Ssal_01853 1.37e-258 712.0 COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,4HA7F@91061|Bacilli 91061|Bacilli K Participates in both transcription termination and antitermination nusA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - ko:K02600 - - - - ko00000,ko03009,ko03021 - - - KH_5,NusA_N,S1 NFINBLID_01291 904306.HMPREF9192_0067 9.2e-64 194.0 COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,4HKBY@91061|Bacilli 91061|Bacilli K Nucleic-acid-binding protein implicated in transcription termination ylxR - - ko:K07742 - - - - ko00000 - - - DUF448 NFINBLID_01292 1046629.Ssal_01850 1.66e-56 176.0 COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes 1239|Firmicutes J ribosomal protein ylxQ - - - - - - - - - - - Ribosomal_L7Ae NFINBLID_01293 1046629.Ssal_01848 0.0 1381.0 COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,4HA8S@91061|Bacilli 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex infB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - ko:K02519 - - - - ko00000,ko03012,ko03029 - - - GTP_EFTU,IF-2,IF2_N NFINBLID_01294 1046629.Ssal_01846 5.68e-76 227.0 COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,4HII1@91061|Bacilli 91061|Bacilli J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA rbfA - - ko:K02834 - - - - ko00000,ko03009 - - - RBFA NFINBLID_01295 1046629.Ssal_01845 7.62e-126 358.0 COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,4HGSU@91061|Bacilli 91061|Bacilli S Belongs to the LOG family - - 3.2.2.10 ko:K06966 ko00230,ko00240,map00230,map00240 - R00182,R00510 RC00063,RC00318 ko00000,ko00001,ko01000 - - - Lysine_decarbox NFINBLID_01296 435842.HMPREF0848_01649 4.82e-83 258.0 COG2348@1|root,COG2348@2|Bacteria,1UZIJ@1239|Firmicutes,4HAQ3@91061|Bacilli 91061|Bacilli V protein involved in methicillin resistance femA - 2.3.2.17 ko:K11694 ko00550,ko01100,map00550,map01100 - R08777 RC00055,RC00096 ko00000,ko00001,ko01000,ko01011 - - - FemAB NFINBLID_01297 435842.HMPREF0848_01649 1.53e-135 393.0 COG2348@1|root,COG2348@2|Bacteria,1UZIJ@1239|Firmicutes,4HAQ3@91061|Bacilli 91061|Bacilli V protein involved in methicillin resistance femA - 2.3.2.17 ko:K11694 ko00550,ko01100,map00550,map01100 - R08777 RC00055,RC00096 ko00000,ko00001,ko01000,ko01011 - - - FemAB NFINBLID_01298 1046629.Ssal_01844 0.0 924.0 COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,4H9T1@91061|Bacilli 91061|Bacilli M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan murE - 6.3.2.13,6.3.2.7 ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 - R02786,R02788 RC00064,RC00090 ko00000,ko00001,ko01000,ko01011 - - - Mur_ligase_C,Mur_ligase_M NFINBLID_01299 1046629.Ssal_01843 0.0 958.0 COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,4H9RY@91061|Bacilli 91061|Bacilli S Membrane protein involved in the export of O-antigen and teichoic acid ytgP GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03328 - - - - ko00000 2.A.66.2 - - Polysacc_synt,Polysacc_synt_C NFINBLID_01300 1046629.Ssal_01842 0.0 1729.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4HTQ4@91061|Bacilli 91061|Bacilli P cation transport ATPase pacL - - - - - - - - - - - Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 NFINBLID_01301 904306.HMPREF9192_0058 4.15e-257 705.0 COG0626@1|root,COG0626@2|Bacteria,1TPC7@1239|Firmicutes,4HAFQ@91061|Bacilli 91061|Bacilli E cystathionine metB GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 2.5.1.48 ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 M00017 R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946 RC00020,RC00056,RC00069,RC00420,RC02848,RC02866 ko00000,ko00001,ko00002,ko01000 - - - Cys_Met_Meta_PP NFINBLID_01302 1046629.Ssal_01839 7.19e-281 767.0 COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,4H9PE@91061|Bacilli 91061|Bacilli E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities malY - 4.4.1.8 ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 - R00782,R01286,R02408,R04941 RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 NFINBLID_01303 1046629.Ssal_01838 0.0 1090.0 COG1621@1|root,COG1621@2|Bacteria 2|Bacteria G Belongs to the glycosyl hydrolase 32 family - - 3.2.1.26,3.2.1.65 ko:K01193,ko:K01212 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R05624,R06088,R11311 RC00028,RC00077,RC03278 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32N,Glyco_hydro_43 NFINBLID_01304 1046629.Ssal_01837 0.0 1439.0 COG1621@1|root,COG1621@2|Bacteria,1TR8C@1239|Firmicutes,4HBYU@91061|Bacilli 91061|Bacilli G Belongs to the glycosyl hydrolase 68 family sacB GO:0005575,GO:0005576 2.4.1.10,2.4.1.9 ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 - R04194,R05140 RC00077,RC00247 ko00000,ko00001,ko01000,ko01003 - GH68 - Glyco_hydro_68,Gram_pos_anchor,SH3_8 NFINBLID_01305 1046629.Ssal_01836 1.06e-145 410.0 COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,4H9Y0@91061|Bacilli 91061|Bacilli F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate upp GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 ko:K00761 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000 - - iSB619.SA_RS11010 UPRTase NFINBLID_01306 1046629.Ssal_01835 3.75e-135 383.0 COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,4HA8J@91061|Bacilli 91061|Bacilli OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins clpP GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0006355,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019538,GO:0030163,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051603,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 3.4.21.92 ko:K01358 ko04112,ko04212,map04112,map04212 - - - ko00000,ko00001,ko01000,ko01002 - - - CLP_protease NFINBLID_01307 1046629.Ssal_01834 1.46e-91 269.0 COG3679@1|root,COG3679@2|Bacteria,1V3R6@1239|Firmicutes,4HGYS@91061|Bacilli 91061|Bacilli S Belongs to the UPF0342 family ylbF - - - - - - - - - - - Com_YlbF NFINBLID_01308 1046629.Ssal_01833 6.15e-62 189.0 COG4471@1|root,COG4471@2|Bacteria,1VF52@1239|Firmicutes,4HNTH@91061|Bacilli 91061|Bacilli S UPF0298 protein ylbG - - - - - - - - - - - DUF2129 NFINBLID_01309 904306.HMPREF9192_0050 3.61e-267 733.0 COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,4H9PI@91061|Bacilli 91061|Bacilli E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component livJ - - ko:K01999 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - Peripla_BP_6 NFINBLID_01310 1046629.Ssal_01831 9.55e-189 526.0 COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,4HBFZ@91061|Bacilli 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family livH - - ko:K01997 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 NFINBLID_01311 1046629.Ssal_01830 1.34e-183 515.0 COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,4HDIU@91061|Bacilli 91061|Bacilli E Belongs to the binding-protein-dependent transport system permease family livM - - ko:K01998 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - BPD_transp_2 NFINBLID_01312 1046629.Ssal_01829 5.4e-175 488.0 COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,4HASG@91061|Bacilli 91061|Bacilli E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component livG - - ko:K01995 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran,BCA_ABC_TP_C NFINBLID_01313 1046629.Ssal_01828 1.32e-157 443.0 COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,4HABJ@91061|Bacilli 91061|Bacilli E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component livF - - ko:K01996 ko02010,ko02024,map02010,map02024 M00237 - - ko00000,ko00001,ko00002,ko02000 3.A.1.4 - - ABC_tran NFINBLID_01314 1046629.Ssal_01826 2.1e-141 400.0 COG0517@1|root,COG0517@2|Bacteria,1V4CD@1239|Firmicutes,4HGX4@91061|Bacilli 91061|Bacilli S CBS domain XK27_04065 - - ko:K04767 - - - - ko00000 - - - ACT,CBS NFINBLID_01315 1046629.Ssal_01825 3.47e-214 592.0 COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,4HAMU@91061|Bacilli 91061|Bacilli E Belongs to the cysteine synthase cystathionine beta- synthase family cysK - 2.5.1.47 ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 M00021 R00897,R03601,R04859 RC00020,RC02814,RC02821 ko00000,ko00001,ko00002,ko01000 - - - PALP NFINBLID_01316 1046629.Ssal_01824 1.76e-139 395.0 COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,4HBIT@91061|Bacilli 91061|Bacilli S YigZ family yvyE - 3.4.13.9 ko:K01271 - - - - ko00000,ko01000,ko01002 - - - DUF1949,UPF0029 NFINBLID_01317 1046629.Ssal_01823 1.65e-301 824.0 COG4098@1|root,COG4098@2|Bacteria,1TPZE@1239|Firmicutes,4HB00@91061|Bacilli 91061|Bacilli L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein) comFA GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - ko:K02240 - M00429 - - ko00000,ko00002,ko02044 3.A.11.1 - - DEAD,Helicase_C,ResIII NFINBLID_01318 904306.HMPREF9192_0040 3.94e-126 362.0 COG1040@1|root,COG1040@2|Bacteria 2|Bacteria K competence protein comFC - - ko:K02242 - M00429 - - ko00000,ko00002,ko02044 - - - Pribosyltran NFINBLID_01319 1046629.Ssal_01821 4.11e-123 351.0 COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,4HFX9@91061|Bacilli 91061|Bacilli J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase hpf GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - ko:K05808 - - - - ko00000,ko03009 - - - Ribosom_S30AE_C,Ribosomal_S30AE NFINBLID_01320 1095726.HMPREF1116_0263 6.34e-48 155.0 COG1226@1|root,COG1226@2|Bacteria 2|Bacteria P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - ko:K10716 - - - - ko00000,ko02000 1.A.1.1,1.A.1.13,1.A.1.17,1.A.1.24,1.A.1.25,1.A.1.6 - - Ion_trans,Ion_trans_2,Na_H_Exchanger,TrkA_C,TrkA_N NFINBLID_01321 888833.HMPREF9421_1153 3.2e-49 157.0 COG5655@1|root,COG5655@2|Bacteria 2|Bacteria L RePlication protein - - - - - - - - - - - - Rep_1 NFINBLID_01322 1046629.Ssal_00877 0.0 1170.0 COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,4H9QH@91061|Bacilli 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision uvrC GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - ko:K03703 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N NFINBLID_01323 1046629.Ssal_00875 2.05e-163 457.0 COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes,4HEXU@91061|Bacilli 91061|Bacilli E hydrolase yfnB - 3.8.1.2 ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 - R05287 RC00697 ko00000,ko00001,ko01000 - - - HAD_2 NFINBLID_01324 1046629.Ssal_00874 6.35e-154 432.0 COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,4HBD6@91061|Bacilli 91061|Bacilli E L-serine dehydratase sdaAB - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - ACT,SDH_beta NFINBLID_01325 1046629.Ssal_00873 4.58e-189 527.0 COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,4HAI1@91061|Bacilli 91061|Bacilli E L-serine dehydratase sdaAA - 4.3.1.17 ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 - R00220,R00590 RC00331,RC02600 ko00000,ko00001,ko01000 - - - SDH_alpha NFINBLID_01326 1046629.Ssal_00871 0.0 2359.0 COG1621@1|root,COG3583@1|root,COG5492@1|root,COG1621@2|Bacteria,COG3583@2|Bacteria,COG5492@2|Bacteria,1TS4M@1239|Firmicutes 1239|Firmicutes G Belongs to the glycosyl hydrolase 32 family - - 3.2.1.80 ko:K03332 ko00051,map00051 - R00879 - ko00000,ko00001,ko01000 - - - Big_2,CW_binding_1,Cadherin-like,DUF1080,G5,Glyco_hydro_32C,Glyco_hydro_32N,Gram_pos_anchor,Laminin_G_2 NFINBLID_01327 1046629.Ssal_00868 3.05e-207 574.0 COG0697@1|root,COG0697@2|Bacteria,1TP9B@1239|Firmicutes,4H9TT@91061|Bacilli 91061|Bacilli EG membrane yjlA - - - - - - - - - - - EmrE NFINBLID_01328 888048.HMPREF8577_0354 2.81e-104 303.0 COG1714@1|root,COG1714@2|Bacteria,1V7WG@1239|Firmicutes,4HK3X@91061|Bacilli 91061|Bacilli S RDD family - - - - - - - - - - - - RDD NFINBLID_01329 1046629.Ssal_00862 7.17e-204 565.0 COG1396@1|root,COG1396@2|Bacteria 2|Bacteria K sequence-specific DNA binding - - - ko:K20342,ko:K20480 ko02024,map02024 - - - ko00000,ko00001,ko03000 - - - HTH_19,HTH_3,TPR_8 NFINBLID_01330 873449.STRCR_1470 1.38e-65 205.0 COG2249@1|root,COG2249@2|Bacteria,1V4UF@1239|Firmicutes,4HH6R@91061|Bacilli 91061|Bacilli S general stress protein ywrO - - ko:K11748 - - - - ko00000,ko02000 2.A.37.1.2 - - Flavodoxin_2 NFINBLID_01331 904306.HMPREF9192_1107 0.0 4088.0 COG1404@1|root,COG1404@2|Bacteria,1TPH1@1239|Firmicutes,4HBQH@91061|Bacilli 91061|Bacilli O Belongs to the peptidase S8 family prtA - - - - - - - - - - - Gram_pos_anchor,Inhibitor_I9,PA,Peptidase_S8,fn3_5 NFINBLID_01332 888746.HMPREF9180_0560 5.89e-100 290.0 COG0454@1|root,COG0454@2|Bacteria,1V1JN@1239|Firmicutes,4HMYM@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_10,Acetyltransf_7 NFINBLID_01333 904306.HMPREF9192_1106 6.34e-182 506.0 COG3694@1|root,COG3694@2|Bacteria,1US4C@1239|Firmicutes,4IRS2@91061|Bacilli 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 NFINBLID_01334 1005705.HMPREF9967_1430 1.27e-182 509.0 COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,4HBVU@91061|Bacilli,43FGB@68892|Streptococcus infantis 91061|Bacilli S ABC-2 family transporter protein M1-956 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_6 NFINBLID_01335 1316408.HSISM1_386 7.81e-238 654.0 COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,4H9NR@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_01338 1046629.Ssal_00505 7.39e-113 337.0 COG2378@1|root,COG2378@2|Bacteria 2|Bacteria K regulation of single-species biofilm formation yfjR GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - - - - - - - - - - HTH_11,HTH_DeoR,WYL NFINBLID_01339 1196322.A370_02674 7.83e-149 455.0 COG1479@1|root,COG1479@2|Bacteria,1TRXF@1239|Firmicutes,24ET3@186801|Clostridia,36NWE@31979|Clostridiaceae 186801|Clostridia S Protein of unknown function DUF262 - - - - - - - - - - - - DUF262 NFINBLID_01340 563038.HMPREF0851_00491 4.52e-251 702.0 COG1479@1|root,COG1479@2|Bacteria,1TSBG@1239|Firmicutes,4HUFT@91061|Bacilli 91061|Bacilli S Protein of unknown function DUF262 - - - - - - - - - - - - DUF1524,DUF262 NFINBLID_01341 1046629.Ssal_00852 1.99e-132 376.0 COG2197@1|root,COG2197@2|Bacteria,1TVTF@1239|Firmicutes,4HAJW@91061|Bacilli 91061|Bacilli K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain desR - - ko:K02479,ko:K07693 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko02022 - - - GerE,Response_reg NFINBLID_01342 904306.HMPREF9192_1102 9.38e-238 656.0 COG4585@1|root,COG4585@2|Bacteria,1TSUE@1239|Firmicutes,4HB9N@91061|Bacilli 91061|Bacilli T Histidine kinase desK GO:0003674,GO:0003824,GO:0004721,GO:0005488,GO:0005515,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 ko:K07778 ko02020,map02020 M00479 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA_3 NFINBLID_01343 322159.STER_1292 8.31e-170 474.0 COG0842@1|root,COG0842@2|Bacteria,1V1AU@1239|Firmicutes 1239|Firmicutes V ABC-2 type transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 NFINBLID_01344 435842.HMPREF0848_00891 5.07e-204 565.0 COG1131@1|root,COG1131@2|Bacteria,1UZ04@1239|Firmicutes,4HDGQ@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein XK27_09825 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_01347 435842.HMPREF0848_00894 6.54e-222 612.0 COG0332@1|root,COG0332@2|Bacteria,1UYNP@1239|Firmicutes,4HECC@91061|Bacilli 91061|Bacilli I synthase III fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C NFINBLID_01348 435842.HMPREF0848_00895 2.45e-307 837.0 COG1541@1|root,COG1541@2|Bacteria,1UYWT@1239|Firmicutes,4HD2R@91061|Bacilli 91061|Bacilli H Coenzyme F390 synthetase - - - - - - - - - - - - AMP-binding NFINBLID_01349 435842.HMPREF0848_00896 1.57e-196 544.0 COG0491@1|root,COG0491@2|Bacteria,1V5YS@1239|Firmicutes,4HIA8@91061|Bacilli 91061|Bacilli S Metallo-beta-lactamase superfamily - - - - - - - - - - - - Lactamase_B NFINBLID_01350 435842.HMPREF0848_00897 6.87e-230 633.0 COG0451@1|root,COG0451@2|Bacteria,1TT3X@1239|Firmicutes,4HFYX@91061|Bacilli 91061|Bacilli M NAD dependent epimerase dehydratase family protein galE1 - - - - - - - - - - - 3Beta_HSD,Epimerase NFINBLID_01351 435842.HMPREF0848_00898 6.37e-296 808.0 COG1819@1|root,COG1819@2|Bacteria,1V064@1239|Firmicutes,4HUGZ@91061|Bacilli 91061|Bacilli CG Glycosyltransferase family 28 C-terminal domain - - - - - - - - - - - - Glyco_tran_28_C NFINBLID_01352 999425.HMPREF9186_00184 8.4e-137 392.0 COG0300@1|root,COG0300@2|Bacteria 2|Bacteria S Belongs to the short-chain dehydrogenases reductases (SDR) family - - 1.1.1.105 ko:K07124,ko:K15734 ko00830,map00830 - R02124 RC00649 ko00000,ko00001,ko01000 - - - adh_short NFINBLID_01353 888048.HMPREF8577_0487 2.28e-253 697.0 COG1215@1|root,COG1215@2|Bacteria 2|Bacteria M transferase activity, transferring glycosyl groups ugcG - 2.4.1.80 ko:K00720 ko00600,ko01100,map00600,map01100 M00066 R01497 RC00005,RC00059 ko00000,ko00001,ko00002,ko01000,ko01003,ko02000 4.D.1.4 GT21 - Glyco_transf_21 NFINBLID_01354 999425.HMPREF9186_00186 3.7e-130 372.0 28MX1@1|root,2ZB48@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - NFINBLID_01355 1316408.HSISM1_1160 1.13e-263 727.0 COG1819@1|root,COG1819@2|Bacteria 2|Bacteria CG transferase activity, transferring hexosyl groups - - 2.4.1.276 ko:K14596 ko00906,map00906 - R07574 RC00005,RC01992 ko00000,ko00001,ko01000,ko01003 - GT1 - Glyco_tran_28_C,Glyco_trans_1_3,UDPGT NFINBLID_01357 435842.HMPREF0848_00900 3.6e-302 827.0 COG0666@1|root,COG0666@2|Bacteria 2|Bacteria G response to abiotic stimulus anK3 - - ko:K07126 - - - - ko00000 - - - Ank_2,Ank_3,Ank_4,DUF1835,SUFU NFINBLID_01358 435842.HMPREF0848_00901 0.0 1122.0 COG0443@1|root,COG0443@2|Bacteria,1TQ6N@1239|Firmicutes,4HCZX@91061|Bacilli 91061|Bacilli O Belongs to the heat shock protein 70 family hscC - - ko:K04045 - - - - ko00000,ko03110 1.A.33 - - HSP70 NFINBLID_01359 904306.HMPREF9192_1097 4.53e-212 587.0 COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,4HBG6@91061|Bacilli 91061|Bacilli S Transporter yocS - - ko:K03453 - - - - ko00000 2.A.28 - iYO844.BSU19350 SBF NFINBLID_01360 264199.stu1331 4.74e-106 305.0 COG0295@1|root,COG0295@2|Bacteria,1V58S@1239|Firmicutes,4HHTM@91061|Bacilli 91061|Bacilli F cytidine deaminase activity - - - - - - - - - - - - dCMP_cyt_deam_1 NFINBLID_01361 1046629.Ssal_00843 5.42e-150 424.0 COG0842@1|root,COG0842@2|Bacteria,1V1AU@1239|Firmicutes,4HHQW@91061|Bacilli 91061|Bacilli V Transporter - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane,ABC2_membrane_3 NFINBLID_01362 1046629.Ssal_00842 9.41e-200 554.0 COG1131@1|root,COG1131@2|Bacteria,1UZ04@1239|Firmicutes,4HDGQ@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein XK27_09825 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_01366 1046629.Ssal_00839 1.67e-120 343.0 COG0727@1|root,COG0727@2|Bacteria 2|Bacteria S metal cluster binding XK27_05000 - - ko:K06940 - - - - ko00000 - - - CxxCxxCC NFINBLID_01367 1046629.Ssal_00838 0.0 1163.0 COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,4H9SH@91061|Bacilli 91061|Bacilli V ABC transporter (permease) - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX NFINBLID_01368 1046629.Ssal_00837 6.05e-171 478.0 COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,4H9UT@91061|Bacilli 91061|Bacilli V ABC transporter, ATP-binding protein yxdL - - ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 M00258,M00731,M00737 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.134 - - ABC_tran NFINBLID_01369 264199.stu1335 9.82e-213 590.0 COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,4HG2J@91061|Bacilli 91061|Bacilli T Histidine kinase - - - - - - - - - - - - HATPase_c NFINBLID_01370 1046629.Ssal_00835 1.23e-157 442.0 COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,4HAUJ@91061|Bacilli 91061|Bacilli KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain graR - - ko:K19082 ko02020,map02020 M00734,M00737 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C NFINBLID_01371 1046629.Ssal_00834 1.25e-127 363.0 COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,4HFNW@91061|Bacilli 91061|Bacilli F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis xpt - 2.4.2.22 ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01229,R02142 RC00063,RC00122 ko00000,ko00001,ko01000 - - iYO844.BSU22070 Pribosyltran NFINBLID_01372 1046629.Ssal_00833 2.96e-284 779.0 COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,4HBAM@91061|Bacilli 91061|Bacilli F xanthine permease pbuX GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0042906,GO:0042907,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:1904823 - ko:K16169 - - - - ko00000,ko02000 2.A.40.3.1 - iSB619.SA_RS02140 Xan_ur_permease NFINBLID_01373 904306.HMPREF9192_1086 5.45e-312 851.0 COG0534@1|root,COG0534@2|Bacteria,1TP5U@1239|Firmicutes,4HA4W@91061|Bacilli 91061|Bacilli V Multidrug efflux pump norM GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - ko:K03327 - - - - ko00000,ko02000 2.A.66.1 - - MatE NFINBLID_01375 1046629.Ssal_00827 1.63e-232 639.0 COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,4HAIV@91061|Bacilli 91061|Bacilli O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine msrA - 1.8.4.11,1.8.4.12 ko:K12267 - - - - ko00000,ko01000 - - - PMSR,SelR NFINBLID_01376 1046629.Ssal_00826 4.69e-298 815.0 COG1114@1|root,COG1114@2|Bacteria,1TQIS@1239|Firmicutes,4HAKA@91061|Bacilli 91061|Bacilli E Component of the transport system for branched-chain amino acids brnQ GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903785,GO:1903825,GO:1905039 - ko:K03311 - - - - ko00000 2.A.26 - - Branch_AA_trans NFINBLID_01377 904306.HMPREF9192_1083 2.5e-230 633.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI NFINBLID_01378 1046629.Ssal_00824 1.03e-87 260.0 2C9NT@1|root,32V8Q@2|Bacteria,1VGVI@1239|Firmicutes,4IRUI@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF3290) - - - - - - - - - - - - DUF3290 NFINBLID_01379 1046629.Ssal_00823 1.68e-138 392.0 COG2323@1|root,COG2323@2|Bacteria,1UYR2@1239|Firmicutes,4HGVG@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF421) - - - - - - - - - - - - DUF421 NFINBLID_01380 1046629.Ssal_00822 1.3e-32 113.0 COG3237@1|root,COG3237@2|Bacteria,1VN9B@1239|Firmicutes,4I22P@91061|Bacilli 91061|Bacilli S CsbD-like - - - - - - - - - - - - CsbD NFINBLID_01381 1046629.Ssal_00820 7.54e-255 741.0 arCOG08054@1|root,2Z8AD@2|Bacteria,1TQ1J@1239|Firmicutes,4HDNN@91061|Bacilli 91061|Bacilli S Carbohydrate-binding domain-containing protein Cthe_2159 - - - - - - - - - - - - Cthe_2159 NFINBLID_01382 435842.HMPREF0848_01140 1.99e-52 169.0 COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli 91061|Bacilli P Protein conserved in bacteria - - - - - - - - - - - - ASCH NFINBLID_01383 1046629.Ssal_00818 2.39e-296 813.0 COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,4HA66@91061|Bacilli 91061|Bacilli E amino acid yfnA - - ko:K03294 - - - - ko00000 2.A.3.2 - - AA_permease_2 NFINBLID_01384 435842.HMPREF0848_00928 0.0 1788.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,Glyco_hydro_25,NLPC_P60,PG_binding_1 NFINBLID_01385 435842.HMPREF0848_00934 9.7e-109 313.0 COG0386@1|root,COG0386@2|Bacteria,1V3M3@1239|Firmicutes,4HH5Q@91061|Bacilli 91061|Bacilli O Belongs to the glutathione peroxidase family gpo - 1.11.1.9 ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 - R00274,R07034,R07035 RC00011,RC00982 ko00000,ko00001,ko01000 - - - GSHPx NFINBLID_01386 1046629.Ssal_00807 1.39e-56 176.0 COG4095@1|root,COG4095@2|Bacteria,1VBI9@1239|Firmicutes,4HN2M@91061|Bacilli 91061|Bacilli S Sugar efflux transporter for intercellular exchange - - - - - - - - - - - - MtN3_slv NFINBLID_01387 888833.HMPREF9421_1062 4.66e-258 709.0 28K0P@1|root,2Z9QJ@2|Bacteria,1TSN2@1239|Firmicutes,4HU6K@91061|Bacilli 91061|Bacilli P FtsX-like permease family - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX NFINBLID_01388 1316408.HSISM1_1672 3.03e-158 444.0 COG1136@1|root,COG1136@2|Bacteria,1U3WD@1239|Firmicutes,4HV7M@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein - - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_01389 1046629.Ssal_00803 5.98e-125 357.0 COG1309@1|root,COG1309@2|Bacteria,1V2BY@1239|Firmicutes,4HPW3@91061|Bacilli 91061|Bacilli K WHG domain - - - - - - - - - - - - TetR_N,WHG NFINBLID_01390 1046629.Ssal_00802 4.07e-217 599.0 COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,4HA57@91061|Bacilli 91061|Bacilli S Aldo keto reductase ydhF - - - - - - - - - - - Aldo_ket_red NFINBLID_01391 1114965.Spaf_1395 2.09e-268 737.0 COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,4HC9K@91061|Bacilli 91061|Bacilli CP ABC-type Na efflux pump, permease component natB - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_3 NFINBLID_01392 1316408.HSISM1_1676 4.74e-211 583.0 COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,4H9RX@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein natA - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran,DUF4162 NFINBLID_01394 435842.HMPREF0848_00944 1.39e-36 124.0 COG1476@1|root,COG1476@2|Bacteria,1VEZ1@1239|Firmicutes,4HNNM@91061|Bacilli 91061|Bacilli K transcriptional XK27_07105 - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 NFINBLID_01395 435842.HMPREF0848_00945 3.63e-52 166.0 2DU7U@1|root,33P99@2|Bacteria,1VQQU@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - NFINBLID_01396 1046629.Ssal_00795 9.94e-142 400.0 COG3560@1|root,COG3560@2|Bacteria,1V1CR@1239|Firmicutes,4HD6W@91061|Bacilli 91061|Bacilli S nitroreductase XK27_02070 - - ko:K07078 - - - - ko00000 - - - Nitroreductase NFINBLID_01397 435842.HMPREF0848_00947 1.18e-193 538.0 COG2514@1|root,COG2514@2|Bacteria,1TPRF@1239|Firmicutes,4HAE7@91061|Bacilli 91061|Bacilli S glyoxalase catE - 1.13.11.2 ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 M00569 R00816,R04089,R05295,R05404,R05406,R07795 RC00387,RC00643,RC01075,RC01364,RC01914 ko00000,ko00001,ko00002,ko01000 - - - Glyoxalase NFINBLID_01398 904306.HMPREF9192_1076 8.17e-98 285.0 COG1959@1|root,COG1959@2|Bacteria,1V6FK@1239|Firmicutes,4HKZD@91061|Bacilli 91061|Bacilli K Transcriptional regulator ywnA_2 - - - - - - - - - - - Rrf2 NFINBLID_01399 904306.HMPREF9192_1075 6.62e-197 546.0 COG4814@1|root,COG4814@2|Bacteria,1V13S@1239|Firmicutes,4HENM@91061|Bacilli 91061|Bacilli E Alpha/beta hydrolase of unknown function (DUF915) - - - - - - - - - - - - DUF915 NFINBLID_01400 904306.HMPREF9192_1074 3.12e-290 795.0 COG1455@1|root,COG1455@2|Bacteria,1V5SI@1239|Firmicutes,4HJTK@91061|Bacilli 91061|Bacilli G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane celB - - ko:K02761 ko00500,ko02060,map00500,map02060 M00275 R11170,R11172 RC00017,RC03206 ko00000,ko00001,ko00002,ko02000 4.A.3.2 - - PTS_EIIC NFINBLID_01401 1046629.Ssal_00789 2.54e-215 595.0 COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HAGA@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein bcrA - - ko:K01990,ko:K19309 ko02010,map02010 M00254,M00747 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.131.1 - - ABC_tran NFINBLID_01402 904306.HMPREF9192_1072 5.75e-164 460.0 2EGU7@1|root,33AKD@2|Bacteria,1VMES@1239|Firmicutes,4HQPP@91061|Bacilli 91061|Bacilli S ABC-2 family transporter protein - - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC2_membrane_4 NFINBLID_01403 546270.GEMHA0001_1118 9.79e-93 296.0 COG1403@1|root,COG1403@2|Bacteria,1VC3P@1239|Firmicutes,4HQVU@91061|Bacilli 91061|Bacilli V HNH nucleases - - - - - - - - - - - - - NFINBLID_01404 546270.GEMHA0001_1119 5.91e-162 495.0 COG3950@1|root,COG3950@2|Bacteria,1VHTQ@1239|Firmicutes,4HX8K@91061|Bacilli 91061|Bacilli S AAA domain, putative AbiEii toxin, Type IV TA system - - - - - - - - - - - - AAA_21 NFINBLID_01405 1046629.Ssal_00786 5.34e-189 527.0 COG0642@1|root,COG2205@2|Bacteria,1UYK9@1239|Firmicutes,4IPWV@91061|Bacilli 91061|Bacilli T His Kinase A (phosphoacceptor) domain - - - - - - - - - - - - HATPase_c,HATPase_c_5,HisKA NFINBLID_01406 435842.HMPREF0848_00959 2.59e-160 449.0 COG0745@1|root,COG0745@2|Bacteria,1UYA6@1239|Firmicutes,4IQ4T@91061|Bacilli 91061|Bacilli T Transcriptional regulatory protein, C terminal - - - - - - - - - - - - Response_reg,Trans_reg_C NFINBLID_01407 1046629.Ssal_00784 5.25e-142 401.0 COG0778@1|root,COG0778@2|Bacteria,1UXYI@1239|Firmicutes,4HBMN@91061|Bacilli 91061|Bacilli C nitroreductase yodC - - - - - - - - - - - Nitroreductase NFINBLID_01408 904306.HMPREF9192_1065 2.16e-143 406.0 COG3619@1|root,COG3619@2|Bacteria,1V9ME@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF1275) - - - - - - - - - - - - DUF1275 NFINBLID_01409 1046629.Ssal_00782 1.88e-52 165.0 COG2026@1|root,COG2026@2|Bacteria 2|Bacteria DJ nuclease activity - - - ko:K06218 - - - - ko00000,ko02048 - - - ParE_toxin NFINBLID_01410 1046629.Ssal_00781 7.27e-42 137.0 2DQ9B@1|root,335EQ@2|Bacteria,1VIWV@1239|Firmicutes,4HQTB@91061|Bacilli 91061|Bacilli - - XK27_10490 - - - - - - - - - - - - NFINBLID_01411 1046629.Ssal_00780 1.46e-201 558.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4HARE@91061|Bacilli 91061|Bacilli C reductase yvgN - - - - - - - - - - - Aldo_ket_red NFINBLID_01412 1046629.Ssal_00779 3.12e-271 743.0 COG0457@1|root,COG0457@2|Bacteria,1VBH7@1239|Firmicutes,4IS2V@91061|Bacilli 91061|Bacilli S Tetratricopeptide repeat - - - - - - - - - - - - - NFINBLID_01413 1046629.Ssal_00777 0.0 2068.0 COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,4HANW@91061|Bacilli 91061|Bacilli G -beta-galactosidase lacL - 3.2.1.23 ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 - R01105,R01678,R03355,R04783,R06114 RC00049,RC00452 ko00000,ko00001,ko01000 - - - Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N NFINBLID_01414 1046629.Ssal_00776 0.0 1219.0 COG2190@1|root,COG2211@1|root,COG2190@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HCDS@91061|Bacilli 91061|Bacilli G transporter lacS GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K11104,ko:K16209 - - - - ko00000,ko02000 2.A.2.1,2.A.2.2 - - MFS_2,PTS_EIIA_1 NFINBLID_01415 1046629.Ssal_00775 3.27e-255 699.0 COG2017@1|root,COG2017@2|Bacteria,1V5UK@1239|Firmicutes,4HTRY@91061|Bacilli 91061|Bacilli G Catalyzes the interconversion of alpha and beta anomers of maltose galM - 5.1.3.3 ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 M00632 R01602,R10619 RC00563 ko00000,ko00001,ko00002,ko01000 - - - Aldose_epim NFINBLID_01416 435842.HMPREF0848_00969 4.24e-248 680.0 COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,4H9U5@91061|Bacilli 91061|Bacilli M Belongs to the NAD(P)-dependent epimerase dehydratase family galE - 5.1.3.2 ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00361,M00362,M00632 R00291,R02984 RC00289 ko00000,ko00001,ko00002,ko01000 - - - Epimerase,GDP_Man_Dehyd NFINBLID_01417 1046629.Ssal_00773 0.0 978.0 COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,4HAYJ@91061|Bacilli 91061|Bacilli G UDPglucose--hexose-1-phosphate uridylyltransferase galT - 2.7.7.12 ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 M00362,M00554,M00632 R00955 RC00002 ko00000,ko00001,ko00002,ko01000 - - - GalP_UDP_tr_C,GalP_UDP_transf NFINBLID_01418 435842.HMPREF0848_00971 6.67e-282 770.0 COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,4HARP@91061|Bacilli 91061|Bacilli G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) galK GO:0005975,GO:0005996,GO:0006012,GO:0008150,GO:0008152,GO:0019318,GO:0044238,GO:0044281,GO:0071704 2.7.1.6 ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 M00554,M00632 R01092 RC00002,RC00078 ko00000,ko00001,ko00002,ko01000,ko04147 - - - GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg NFINBLID_01419 1046629.Ssal_00771 6.38e-233 641.0 COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,4HC9Z@91061|Bacilli 91061|Bacilli K Transcriptional regulator galR - - ko:K02529 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_3 NFINBLID_01420 904306.HMPREF9192_1062 0.0 1059.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli 91061|Bacilli G COG0366 Glycosidases dexB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.70 ko:K01215 - - - - ko00000,ko01000 - - - Alpha-amylase,DUF3459,Malt_amylase_C NFINBLID_01421 1034769.KB910518_gene3613 3.78e-246 688.0 COG0366@1|root,COG0366@2|Bacteria,1TR93@1239|Firmicutes,4HEKC@91061|Bacilli,26TSJ@186822|Paenibacillaceae 91061|Bacilli G Alpha amylase, catalytic domain - - 2.4.1.329 ko:K21350 - - - - ko00000,ko01000 - GH13 - Alpha-amylase NFINBLID_01422 931276.Cspa_c57840 3.14e-120 355.0 COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,36F3R@31979|Clostridiaceae 186801|Clostridia G pfkB family carbohydrate kinase iolC - 2.7.1.4,2.7.1.92 ko:K00847,ko:K03338 ko00051,ko00500,ko00520,ko00562,ko01100,ko01120,map00051,map00500,map00520,map00562,map01100,map01120 - R00760,R00867,R03920,R05661 RC00002,RC00017 ko00000,ko00001,ko01000 - - - PfkB NFINBLID_01423 1123311.KB904476_gene1298 2.02e-240 664.0 COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,4HAMQ@91061|Bacilli 91061|Bacilli P Belongs to the ABC transporter superfamily msmK - - ko:K10112 ko02010,map02010 M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1 - - ABC_tran,TOBE,TOBE_2 NFINBLID_01424 1282665.H353_03773 9.24e-183 510.0 COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,4HCEH@91061|Bacilli 91061|Bacilli P ABC-type sugar transport system, permease component msmG - - ko:K10119 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 NFINBLID_01425 888049.HMPREF8578_2007 6.2e-187 521.0 COG1175@1|root,COG1175@2|Bacteria,1TQB1@1239|Firmicutes,4HDV6@91061|Bacilli,1WPP8@1303|Streptococcus oralis 91061|Bacilli P Binding-protein-dependent transport system inner membrane component msmF - - ko:K10118 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - BPD_transp_1 NFINBLID_01426 864567.HMPREF8571_1568 1.36e-247 686.0 COG1653@1|root,COG1653@2|Bacteria,1TQJE@1239|Firmicutes,4HCBS@91061|Bacilli,2TPMQ@28037|Streptococcus mitis 91061|Bacilli G Bacterial extracellular solute-binding protein msmE - - ko:K10117 ko02010,map02010 M00196 - - ko00000,ko00001,ko00002,ko02000 3.A.1.1.28 - - SBP_bac_1,SBP_bac_8 NFINBLID_01427 435842.HMPREF0848_00973 0.0 1389.0 COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli 91061|Bacilli G alpha-galactosidase aga - 3.2.1.22 ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 - R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091 RC00049,RC00059,RC00451 ko00000,ko00001,ko01000 - - - Glyco_hydro_36C,Glyco_hydro_36N,Melibiase NFINBLID_01428 435842.HMPREF0848_00974 1.95e-183 511.0 COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,4ISD2@91061|Bacilli 91061|Bacilli K AraC family transcriptional regulator - - - - - - - - - - - - AraC_binding,HTH_18,HTH_AraC NFINBLID_01429 904306.HMPREF9192_1062 0.0 991.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli 91061|Bacilli G COG0366 Glycosidases dexB GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.2.1.70 ko:K01215 - - - - ko00000,ko01000 - - - Alpha-amylase,DUF3459,Malt_amylase_C NFINBLID_01430 1046629.Ssal_00769 1.22e-289 793.0 COG0642@1|root,COG0642@2|Bacteria,1TQZD@1239|Firmicutes,4HDFP@91061|Bacilli 91061|Bacilli T Histidine kinase vncS - 2.7.13.3 ko:K10819 - - - - ko00000,ko01000 - - - HAMP,HATPase_c,HATPase_c_5,HisKA NFINBLID_01431 999425.HMPREF9186_00549 6.12e-149 419.0 COG0745@1|root,COG0745@2|Bacteria,1TT7R@1239|Firmicutes,4HG6F@91061|Bacilli 91061|Bacilli K Response regulator receiver domain protein vncR - - - - - - - - - - - Response_reg,Trans_reg_C NFINBLID_01432 904306.HMPREF9192_1059 8.63e-309 844.0 COG0577@1|root,COG0577@2|Bacteria,1TPSE@1239|Firmicutes,4HDMR@91061|Bacilli 91061|Bacilli V Efflux ABC transporter, permease protein vex3 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX NFINBLID_01433 1046629.Ssal_00766 2.14e-141 400.0 COG1136@1|root,COG1136@2|Bacteria,1TP5M@1239|Firmicutes,4HBJW@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein vex2 - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_01434 904306.HMPREF9192_1057 4.92e-270 743.0 COG0577@1|root,COG0577@2|Bacteria,1TT8B@1239|Firmicutes,4HFDY@91061|Bacilli 91061|Bacilli V Efflux ABC transporter, permease protein vex1 - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD NFINBLID_01435 1046629.Ssal_00764 0.0 976.0 COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,4HDNX@91061|Bacilli 91061|Bacilli S Belongs to the UPF0371 family XK27_07020 - - - - - - - - - - - DUF1846 NFINBLID_01436 1511.CLOST_2006 2.14e-06 50.8 2BYV2@1|root,33ICM@2|Bacteria,1VMF3@1239|Firmicutes,256VA@186801|Clostridia 186801|Clostridia - - - - - - - - - - - - - - - NFINBLID_01437 1046629.Ssal_00761 1.13e-255 702.0 COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,4HC8K@91061|Bacilli 91061|Bacilli C glycerol dehydrogenase gldA - 1.1.1.6 ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 - R01034,R10715,R10717 RC00029,RC00117,RC00670 ko00000,ko00001,ko01000 - - - Fe-ADH NFINBLID_01438 1046629.Ssal_00760 2.22e-231 637.0 COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,4HAPJ@91061|Bacilli 91061|Bacilli S oxidoreductase XK27_10475 - - - - - - - - - - - GFO_IDH_MocA NFINBLID_01439 1046629.Ssal_00759 2e-77 231.0 COG3412@1|root,COG3412@2|Bacteria,1VF32@1239|Firmicutes 1239|Firmicutes S dihydroxyacetone kinase, phosphotransfer subunit dhaM GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05881 ko00561,map00561 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000,ko02000 - - - EIIA-man NFINBLID_01440 1046629.Ssal_00758 1.71e-124 355.0 COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,4HGZY@91061|Bacilli 91061|Bacilli S Dihydroxyacetone kinase dhaL GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0047324,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.1.121 ko:K05879 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak2 NFINBLID_01441 1046629.Ssal_00757 2.04e-228 630.0 COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,4H9VS@91061|Bacilli 91061|Bacilli G Dihydroxyacetone kinase dhaK GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121 ko:K05878 ko00561,ko01100,map00561,map01100 - R01012 RC00015,RC00017 ko00000,ko00001,ko01000 - - - Dak1 NFINBLID_01442 1046629.Ssal_00756 1.27e-289 792.0 COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TSE8@1239|Firmicutes 1239|Firmicutes K Psort location CytoplasmicMembrane, score - - - - - - - - - - - - Acetyltransf_7,ThrE,ThrE_2 NFINBLID_01443 999425.HMPREF9186_00431 2.04e-173 486.0 COG0639@1|root,COG0639@2|Bacteria,1VDTG@1239|Firmicutes,4HKC1@91061|Bacilli 91061|Bacilli T Ser Thr phosphatase family protein - - - - - - - - - - - - Metallophos_2 NFINBLID_01444 927666.SOR_0713 1.59e-45 149.0 2DKHV@1|root,309HT@2|Bacteria,1U54E@1239|Firmicutes,4I1BW@91061|Bacilli 91061|Bacilli S Immunity protein 41 - - - - - - - - - - - - Imm41 NFINBLID_01445 1046629.Ssal_00750 0.0 1293.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N NFINBLID_01446 1069533.Sinf_1729 4.9e-13 67.0 2EGBF@1|root,33A3A@2|Bacteria,1VP2X@1239|Firmicutes,4HS3U@91061|Bacilli 91061|Bacilli S Enterocin A Immunity - - - - - - - - - - - - EntA_Immun NFINBLID_01447 469609.HMPREF0847_01534 1.07e-14 75.9 COG5658@1|root,COG5658@2|Bacteria 2|Bacteria S integral membrane protein - - - - - - - - - - - - DUF1648,SdpI NFINBLID_01448 1046629.Ssal_00745 1.21e-58 181.0 COG0640@1|root,COG0640@2|Bacteria,1UKJV@1239|Firmicutes,4ITJ6@91061|Bacilli 91061|Bacilli K helix_turn_helix, Arsenical Resistance Operon Repressor - - - - - - - - - - - - HTH_20 NFINBLID_01449 1046629.Ssal_00744 5.07e-111 324.0 COG4377@1|root,COG4377@2|Bacteria 2|Bacteria S Putative membrane peptidase family (DUF2324) yhfC - - - - - - - - - - - DUF2324 NFINBLID_01450 1046629.Ssal_00742 0.0 2798.0 COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli 91061|Bacilli M KxYKxGKxW signal domain protein - GO:0005575,GO:0005576 2.4.1.5 ko:K00689 ko00500,ko02020,map00500,map02020 - R02120,R06066 RC00028 ko00000,ko00001,ko01000 - GH13 - Big_2,CW_binding_1,Glyco_hydro_70 NFINBLID_01452 1046629.Ssal_00740 0.0 1071.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 NFINBLID_01453 1046629.Ssal_00738 0.0 2583.0 COG0366@1|root,COG5263@1|root,COG0366@2|Bacteria,COG5263@2|Bacteria,1VQXK@1239|Firmicutes,4HEIA@91061|Bacilli 91061|Bacilli M KxYKxGKxW signal domain protein - GO:0005575,GO:0005576 2.4.1.5 ko:K00689 ko00500,ko02020,map00500,map02020 - R02120,R06066 RC00028 ko00000,ko00001,ko01000 - GH13 - Big_2,CW_binding_1,Glyco_hydro_70 NFINBLID_01454 1046629.Ssal_00737 0.0 1721.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 NFINBLID_01455 1046629.Ssal_00736 0.0 1476.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 NFINBLID_01456 1046629.Ssal_00735 0.0 2243.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 NFINBLID_01457 1046629.Ssal_00734 6.92e-104 355.0 COG5263@1|root,COG5263@2|Bacteria,1V0PX@1239|Firmicutes 1239|Firmicutes M Putative cell wall binding repeat tcdB - - ko:K11063 ko02024,map02024 - - - ko00000,ko00001,ko02042 - - - CW_binding_1,LRR_5,NLPC_P60,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N NFINBLID_01458 1046629.Ssal_00732 0.0 1397.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 NFINBLID_01459 904306.HMPREF9192_1032 1.05e-129 369.0 COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,4HFSZ@91061|Bacilli 91061|Bacilli H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS pdxT GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 ko:K08681 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SNO NFINBLID_01460 1046629.Ssal_00730 3.25e-197 548.0 COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,4H9RA@91061|Bacilli 91061|Bacilli H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively pdxS GO:0003674,GO:0005488,GO:0005515,GO:0042802 4.3.3.6 ko:K06215 ko00750,map00750 - R07456 RC00010,RC01783,RC03043 ko00000,ko00001,ko01000 - - - SOR_SNZ NFINBLID_01461 1046629.Ssal_00729 0.0 1664.0 COG5263@1|root,COG5263@2|Bacteria,1V0PX@1239|Firmicutes 1239|Firmicutes M Putative cell wall binding repeat tcdB - - ko:K11063 ko02024,map02024 - - - ko00000,ko00001,ko02042 - - - CW_binding_1,LRR_5,NLPC_P60,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N NFINBLID_01462 1046629.Ssal_00728 0.0 1132.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 NFINBLID_01463 1046629.Ssal_00725 6.4e-240 711.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 NFINBLID_01464 1046629.Ssal_00725 0.0 1750.0 COG5263@1|root,COG5263@2|Bacteria 2|Bacteria S dextransucrase activity - - - - - - - - - - - - CW_binding_1,NLPC_P60,PG_binding_1 NFINBLID_01465 435842.HMPREF0848_00996 6.24e-293 839.0 COG5263@1|root,COG5263@2|Bacteria,1V0PX@1239|Firmicutes 1239|Firmicutes M Putative cell wall binding repeat tcdB - - ko:K11063 ko02024,map02024 - - - ko00000,ko00001,ko02042 - - - CW_binding_1,LRR_5,NLPC_P60,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N NFINBLID_01466 1046629.Ssal_02154 0.0 1246.0 COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,4HAJB@91061|Bacilli 91061|Bacilli O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins ftsH GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0030428,GO:0032502,GO:0042623,GO:0043170,GO:0043934,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - ko:K03798 - M00742 - - ko00000,ko00002,ko01000,ko01002,ko03110 - - - AAA,FtsH_ext,Peptidase_M41 NFINBLID_01467 1046629.Ssal_02155 3.15e-126 359.0 COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,4HFZ2@91061|Bacilli 91061|Bacilli F Belongs to the purine pyrimidine phosphoribosyltransferase family hpt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,6.3.4.19 ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 - R00190,R01132,R01229,R02142,R08237,R08238,R08245 RC00063,RC00122 ko00000,ko00001,ko01000,ko03016 - - - Pribosyltran NFINBLID_01468 1046629.Ssal_02156 3.96e-293 801.0 COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,4H9ZM@91061|Bacilli 91061|Bacilli D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine tilS - 2.4.2.8,6.3.4.19 ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 - R01132,R01229,R02142,R09597 RC00063,RC00122,RC02633,RC02634 ko00000,ko00001,ko01000,ko03016 - - - ATP_bind_3,TilS,TilS_C NFINBLID_01469 1046629.Ssal_02157 8.36e-295 806.0 COG2367@1|root,COG2367@2|Bacteria,1VGXR@1239|Firmicutes,4IPWW@91061|Bacilli 91061|Bacilli V Beta-lactamase enzyme family - - 3.5.2.6 ko:K01467 ko01501,ko02020,map01501,map02020 M00628 R06363 RC01499 ko00000,ko00001,ko00002,ko01000 - - - Beta-lactamase2,SH3_8 NFINBLID_01471 322159.STER_0009 3.9e-79 235.0 COG2919@1|root,COG2919@2|Bacteria,1VKC5@1239|Firmicutes,4HR53@91061|Bacilli 91061|Bacilli D Septum formation initiator divIC - - ko:K13052 - - - - ko00000,ko03036 - - - DivIC NFINBLID_01472 1046629.Ssal_02160 1.87e-53 168.0 COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,4HKJJ@91061|Bacilli 91061|Bacilli J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) yabO - - - - - - - - - - - S4 NFINBLID_01473 1046629.Ssal_02161 0.0 2234.0 COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,4H9NB@91061|Bacilli 91061|Bacilli L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site mfd - - ko:K03723 ko03420,map03420 - - - ko00000,ko00001,ko01000,ko03400 - - - CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF NFINBLID_01474 1046629.Ssal_02162 5.18e-134 379.0 COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,4HH2Z@91061|Bacilli 91061|Bacilli J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis pth GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 ko:K01056 - - - - ko00000,ko01000,ko03012 - - - Pept_tRNA_hydro NFINBLID_01475 1046629.Ssal_02163 7.47e-259 710.0 COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,4H9SQ@91061|Bacilli 91061|Bacilli J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner ychF GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - ko:K06942 - - - - ko00000,ko03009 - - - MMR_HSR1,YchF-GTPase_C NFINBLID_01476 1046629.Ssal_02164 8.11e-40 131.0 COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,4HNHU@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria yyzM - - - - - - - - - - - DUF951 NFINBLID_01477 904306.HMPREF9192_1861 3.38e-254 699.0 COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,4H9TF@91061|Bacilli 91061|Bacilli L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria dnaN - 2.7.7.7 ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3 NFINBLID_01478 1046629.Ssal_00001 0.0 883.0 COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,4H9MW@91061|Bacilli 91061|Bacilli L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids dnaA GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - ko:K02313 ko02020,ko04112,map02020,map04112 - - - ko00000,ko00001,ko03032,ko03036 - - - Bac_DnaA,Bac_DnaA_C,DnaA_N NFINBLID_01479 1046629.Ssal_00002 5.59e-173 483.0 COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,4H9TB@91061|Bacilli 91061|Bacilli K Belongs to the ParB family spo0J GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - ko:K03497 - - - - ko00000,ko03000,ko03036,ko04812 - - - HTH_3,KorB,ParBc NFINBLID_01480 1046629.Ssal_00003 2.04e-274 753.0 COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,4HA31@91061|Bacilli 91061|Bacilli O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain' htrA GO:0008150,GO:0009266,GO:0009628,GO:0050896 3.4.21.107 ko:K04771 ko01503,ko02020,map01503,map02020 M00728 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 - - - PDZ_2,Trypsin_2 NFINBLID_01481 1046629.Ssal_00004 4.8e-104 301.0 COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,4HFP8@91061|Bacilli 91061|Bacilli J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA rlmH - 2.1.1.177 ko:K00783 - - - - ko00000,ko01000,ko03009 - - - SPOUT_MTase NFINBLID_01482 1046629.Ssal_00005 5.23e-152 428.0 COG3619@1|root,COG3619@2|Bacteria 2|Bacteria S Protein of unknown function (DUF1275) yoaK - - - - - - - - - - - DUF1275 NFINBLID_01486 1046629.Ssal_00006 0.0 1611.0 COG4485@1|root,COG4485@2|Bacteria,1TRR1@1239|Firmicutes,4HCR9@91061|Bacilli 91061|Bacilli S Bacterial membrane protein YfhO XK27_10405 - - - - - - - - - - - YfhO NFINBLID_01487 904306.HMPREF9192_1872 0.0 1052.0 COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,4HATH@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein ykpA - - - - - - - - - - - ABC_tran,ABC_tran_Xtn NFINBLID_01488 1046629.Ssal_00008 1.09e-192 536.0 COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,4H9N6@91061|Bacilli 91061|Bacilli S membrane XK27_10395 - - - - - - - - - - - DUF2179,YitT_membrane NFINBLID_01489 1046629.Ssal_00009 1.07e-240 662.0 COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,4HA1K@91061|Bacilli 91061|Bacilli J Tryptophanyl-tRNA synthetase trpS GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 ko:K01867 ko00970,map00970 M00359,M00360 R03664 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_1b NFINBLID_01490 1046629.Ssal_00010 0.0 942.0 COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,4H9V3@91061|Bacilli 91061|Bacilli F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth guaB GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 M00050 R01130,R08240 RC00143,RC02207 ko00000,ko00001,ko00002,ko01000,ko04147 - - - CBS,IMPDH NFINBLID_01491 1046629.Ssal_00011 1.14e-255 702.0 COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,4HA0W@91061|Bacilli 91061|Bacilli L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP recF GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - ko:K03629 ko03440,map03440 - - - ko00000,ko00001,ko03400 - - - SMC_N NFINBLID_01492 1046629.Ssal_00012 2.83e-73 221.0 COG2501@1|root,COG2501@2|Bacteria,1VKF4@1239|Firmicutes,4HRX5@91061|Bacilli 91061|Bacilli S S4 domain protein YaaA yaaA - - - - - - - - - - - S4_2 NFINBLID_01493 1046629.Ssal_00013 3.13e-292 798.0 COG0612@1|root,COG0612@2|Bacteria,1TPN6@1239|Firmicutes,4H9P5@91061|Bacilli 91061|Bacilli S Peptidase M16 albE - - - - - - - - - - - Peptidase_M16_C NFINBLID_01494 1046629.Ssal_00014 6.17e-299 816.0 COG0612@1|root,COG0612@2|Bacteria,1TP5I@1239|Firmicutes,4H9YG@91061|Bacilli 91061|Bacilli S Peptidase M16 ymfH - - - - - - - - - - - Peptidase_M16,Peptidase_M16_C NFINBLID_01495 1046629.Ssal_00015 4.34e-162 457.0 COG1426@1|root,COG1426@2|Bacteria 2|Bacteria S sequence-specific DNA binding - - - ko:K15539 - - - - ko00000 - - - DUF4115,HTH_25,HTH_3 NFINBLID_01496 1046629.Ssal_00016 2.2e-117 337.0 COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,4HCEX@91061|Bacilli 91061|Bacilli I Belongs to the CDP-alcohol phosphatidyltransferase class-I family pgsA GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.5 ko:K00995 ko00564,ko01100,map00564,map01100 - R01801 RC00002,RC00017,RC02795 ko00000,ko00001,ko01000 - - iSB619.SA_RS06365 CDP-OH_P_transf NFINBLID_01497 1046629.Ssal_00017 1.23e-191 532.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4H9R8@91061|Bacilli 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA1 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16786 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran NFINBLID_01498 1046629.Ssal_00018 2.91e-192 534.0 COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,4HA7T@91061|Bacilli 91061|Bacilli P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfA2 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16787 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ABC_tran NFINBLID_01499 264199.stu2007 6.19e-170 476.0 COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,4H9VT@91061|Bacilli 91061|Bacilli P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates ecfT GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015238,GO:0015711,GO:0015893,GO:0016020,GO:0022857,GO:0032217,GO:0032218,GO:0034220,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0090482,GO:0098656 - ko:K16785 ko02010,map02010 M00582 - - ko00000,ko00001,ko00002,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - CbiQ NFINBLID_01500 435842.HMPREF0848_01703 1.56e-102 300.0 COG1388@1|root,COG1388@2|Bacteria,1VA10@1239|Firmicutes,4HMUH@91061|Bacilli 91061|Bacilli M LysM domain protein lytE - - - - - - - - - - - LysM NFINBLID_01501 1046629.Ssal_00021 4.38e-122 353.0 COG0741@1|root,COG0741@2|Bacteria,1VGPA@1239|Firmicutes,4HP1I@91061|Bacilli 91061|Bacilli M Immunodominant staphylococcal antigen A isaA - - - - - - - - - - - DUF348,G5,LysM,SLT,Transglycosylas NFINBLID_01502 1046629.Ssal_00022 0.0 1063.0 COG4485@1|root,COG4485@2|Bacteria,1V0XZ@1239|Firmicutes,4HEBN@91061|Bacilli 91061|Bacilli S Bacterial membrane protein, YfhO - - - - - - - - - - - - - NFINBLID_01503 1046629.Ssal_00023 8.99e-277 756.0 COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,4HBJ6@91061|Bacilli 91061|Bacilli J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 mnmA GO:0002097,GO:0002098,GO:0002143,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.8.1.13 ko:K00566 ko04122,map04122 - R08700 RC02313,RC02315 ko00000,ko00001,ko01000,ko03016 - - - tRNA_Me_trans NFINBLID_01504 467705.SGO_0023 2.48e-128 366.0 COG2095@1|root,COG2095@2|Bacteria,1V81W@1239|Firmicutes,4HIUV@91061|Bacilli 91061|Bacilli U UPF0056 membrane protein yvbG - - ko:K05595 - - - - ko00000,ko02000 2.A.95.1 - - MarC NFINBLID_01505 1046629.Ssal_00025 0.0 1229.0 COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,4HA6S@91061|Bacilli 91061|Bacilli D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 gidA GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - ko:K03495 - - R08701 RC00053,RC00209,RC00870 ko00000,ko03016,ko03036 - - - GIDA,GIDA_assoc NFINBLID_01506 904306.HMPREF9192_1894 0.0 1218.0 COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,4HBVH@91061|Bacilli 91061|Bacilli T signaling protein consisting of a modified GGDEF domain and a DHH domain yybT - - - - - - - - - - - DHH,DHHA1 NFINBLID_01507 1046629.Ssal_00027 1.45e-97 284.0 COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,4HIKJ@91061|Bacilli 91061|Bacilli J binds to the 23S rRNA rplI GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02939 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L9_C,Ribosomal_L9_N NFINBLID_01508 1046629.Ssal_00028 1.1e-313 856.0 COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,4H9Y8@91061|Bacilli 91061|Bacilli L Participates in initiation and elongation during chromosome replication dnaC GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 ko:K02314 ko03030,ko04112,map03030,map04112 - - - ko00000,ko00001,ko01000,ko03032 - - - DnaB,DnaB_C NFINBLID_01509 1046629.Ssal_00029 6.16e-63 192.0 COG4466@1|root,COG4466@2|Bacteria,1VPZY@1239|Firmicutes,4HSFF@91061|Bacilli 91061|Bacilli S Biofilm formation stimulator VEG WQ51_01655 - - - - - - - - - - - VEG NFINBLID_01510 1046629.Ssal_00030 1.25e-141 400.0 COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,4HAC9@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit rpsD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - ko:K02986 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S4,S4 NFINBLID_01511 1260356.D920_01191 2.64e-13 64.7 2914P@1|root,2ZNS1@2|Bacteria,1W3FT@1239|Firmicutes,4I23Q@91061|Bacilli,4B40K@81852|Enterococcaceae 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01512 1046629.Ssal_00032 7.66e-71 214.0 COG3759@1|root,COG3759@2|Bacteria,1VAEU@1239|Firmicutes 1239|Firmicutes M Membrane XK27_04840 - - ko:K08987 - - - - ko00000 - - - DUF1304 NFINBLID_01513 1046629.Ssal_00033 2.69e-122 349.0 COG1309@1|root,COG1309@2|Bacteria 2|Bacteria K transcriptional regulator XK27_06935 - - - - - - - - - - - TetR_C_8,TetR_N NFINBLID_01514 904306.HMPREF9192_1903 3.48e-260 748.0 COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,4H9T9@91061|Bacilli 91061|Bacilli V domain protein XK27_06930 - - ko:K01421 - - - - ko00000 - - - ABC2_membrane,ABC2_membrane_3,DUF3533 NFINBLID_01515 1046629.Ssal_00035 3.09e-146 418.0 COG3595@1|root,COG3595@2|Bacteria,1VGGF@1239|Firmicutes 1239|Firmicutes S Putative adhesin - - - - - - - - - - - - DUF4097 NFINBLID_01516 904306.HMPREF9192_1905 8.21e-90 268.0 COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,4HSRQ@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1700) - - - - - - - - - - - - DUF1700 NFINBLID_01517 904306.HMPREF9192_1906 4.17e-67 204.0 COG1695@1|root,COG1695@2|Bacteria,1VIVQ@1239|Firmicutes,4IR4R@91061|Bacilli 91061|Bacilli K transcriptional regulator, PadR family XK27_06915 - - ko:K10947 - - - - ko00000,ko03000 - - - PadR NFINBLID_01518 904306.HMPREF9192_1907 1.08e-146 412.0 COG0494@1|root,COG0494@2|Bacteria,1V6SF@1239|Firmicutes,4HG46@91061|Bacilli 91061|Bacilli L hydrolase XK27_06885 - - - - - - - - - - - NUDIX NFINBLID_01522 1046629.Ssal_00051 1.22e-26 97.4 COG0267@1|root,COG0267@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL33 family rpmG GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02913 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L33 NFINBLID_01523 1046629.Ssal_00052 3.57e-35 119.0 COG0333@1|root,COG0333@2|Bacteria,1VKMZ@1239|Firmicutes,4HR2Q@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL32 family rpmF - - ko:K02911 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_L32p NFINBLID_01524 1046629.Ssal_00053 2.9e-276 754.0 COG0620@1|root,COG0620@2|Bacteria,1TPDQ@1239|Firmicutes,4HADW@91061|Bacilli 91061|Bacilli E Methionine synthase metE - 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_2 NFINBLID_01525 1046629.Ssal_00054 5.54e-18 82.4 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NFINBLID_01526 1046629.Ssal_00054 1.24e-62 204.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NFINBLID_01527 1046629.Ssal_00054 2.5e-71 228.0 COG1263@1|root,COG1264@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NFINBLID_01528 1046629.Ssal_00055 1.71e-301 823.0 COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,4HAM2@91061|Bacilli 91061|Bacilli J histidyl-tRNA synthetase hisS - 6.1.1.21 ko:K01892 ko00970,map00970 M00359,M00360 R03655 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - HGTP_anticodon,tRNA-synt_His NFINBLID_01530 1046629.Ssal_00058 0.0 1127.0 COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,4HACD@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) aspS - 6.1.1.12 ko:K01876 ko00970,map00970 M00359,M00360 R05577 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - GAD,tRNA-synt_2,tRNA_anti-codon NFINBLID_01531 1046629.Ssal_00059 7.26e-214 592.0 COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,4HBPR@91061|Bacilli 91061|Bacilli S cog cog1284 XK27_01785 - - - - - - - - - - - DUF2179,YitT_membrane NFINBLID_01532 1046629.Ssal_00060 1.39e-153 433.0 COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,4HFN2@91061|Bacilli 91061|Bacilli S Belongs to the UPF0246 family XK27_08125 - - ko:K09861 - - - - ko00000 - - - H2O2_YaaD NFINBLID_01533 1046629.Ssal_00061 2.44e-147 414.0 COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,4HGJ9@91061|Bacilli 91061|Bacilli O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine nrdG - 1.97.1.4 ko:K04068 - - R04710 - ko00000,ko01000 - - - Fer4_12,Radical_SAM NFINBLID_01534 904306.HMPREF9192_1930 1.16e-112 323.0 COG3981@1|root,COG3981@2|Bacteria,1V1C4@1239|Firmicutes,4HG6C@91061|Bacilli 91061|Bacilli K acetyltransferase - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_3 NFINBLID_01535 435842.HMPREF0848_01736 7.68e-20 80.1 2DEKJ@1|root,2ZNBP@2|Bacteria,1TXD1@1239|Firmicutes,4HZYT@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01536 1046629.Ssal_00064 0.0 1481.0 COG1327@1|root,COG1328@1|root,COG1327@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,4HBIY@91061|Bacilli 91061|Bacilli F Ribonucleoside-triphosphate reductase nrdD - 1.1.98.6 ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 M00053 R11633,R11634,R11635,R11636 RC00613 ko00000,ko00001,ko00002,ko01000 - - - ATP-cone,NRDD NFINBLID_01537 1046629.Ssal_00065 0.0 1006.0 2F2IJ@1|root,33VFI@2|Bacteria,1V9D8@1239|Firmicutes,4HS77@91061|Bacilli 91061|Bacilli S the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - - NFINBLID_01538 1046629.Ssal_00066 1.34e-62 192.0 COG3906@1|root,COG3906@2|Bacteria,1VAPW@1239|Firmicutes,4HKV7@91061|Bacilli 91061|Bacilli S Belongs to the UPF0473 family yrzB - - - - - - - - - - - DUF1292 NFINBLID_01539 435842.HMPREF0848_01740 9.82e-92 268.0 COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,4HH04@91061|Bacilli 91061|Bacilli L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA yrrK GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K07447 - - - - ko00000,ko01000 - - - RuvX NFINBLID_01540 1046629.Ssal_00068 9.75e-59 181.0 COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,4HKD0@91061|Bacilli 91061|Bacilli S Belongs to the UPF0297 family yrzL - - - - - - - - - - - DUF965 NFINBLID_01541 1046629.Ssal_00069 1.73e-36 123.0 COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,4HNIK@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL28 family rpmB - - ko:K02902 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L28 NFINBLID_01542 1046629.Ssal_00070 6.93e-299 816.0 COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,4HAIS@91061|Bacilli 91061|Bacilli L ATPase related to the helicase subunit of the Holliday junction resolvase rarA - - ko:K07478 - - - - ko00000 - - - AAA,AAA_assoc_2,MgsA_C,RuvB_N NFINBLID_01544 1046629.Ssal_00076 2.16e-116 333.0 COG0563@1|root,COG0563@2|Bacteria,1V7AW@1239|Firmicutes,4HH8A@91061|Bacilli 91061|Bacilli F topology modulation protein flaR - - - - - - - - - - - - NFINBLID_01545 1046629.Ssal_00077 0.0 862.0 COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,4H9YT@91061|Bacilli 91061|Bacilli F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP purA GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 M00049 R01135 RC00458,RC00459 ko00000,ko00001,ko00002,ko01000 - - - Adenylsucc_synt NFINBLID_01546 1046629.Ssal_00078 6.56e-106 305.0 COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,4HIZN@91061|Bacilli 91061|Bacilli T Belongs to the low molecular weight phosphotyrosine protein phosphatase family ptpA - 3.1.3.48 ko:K01104 - - - - ko00000,ko01000 - - - LMWPc NFINBLID_01547 1046629.Ssal_00079 1.21e-47 157.0 COG4642@1|root,COG4642@2|Bacteria,1TRNW@1239|Firmicutes 1239|Firmicutes S MORN repeat protein - - - - - - - - - - - - MORN NFINBLID_01548 1046629.Ssal_00080 0.0 1157.0 COG1835@1|root,COG1835@2|Bacteria,1U6DU@1239|Firmicutes,4H9XT@91061|Bacilli 91061|Bacilli I Acyltransferase XK27_09800 - - - - - - - - - - - Acyl_transf_3 NFINBLID_01549 1046629.Ssal_00081 7.25e-240 659.0 COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,4HBMW@91061|Bacilli 91061|Bacilli L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing ruvB - 3.6.4.12 ko:K03551 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - RuvB_C,RuvB_N NFINBLID_01550 1046629.Ssal_00083 4.29e-64 196.0 COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,4HIKH@91061|Bacilli 91061|Bacilli J Involved in the binding of tRNA to the ribosomes rpsJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02946 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S10 NFINBLID_01551 1046629.Ssal_00084 3.17e-142 402.0 COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,4HAEN@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit rplC GO:0008150,GO:0009893,GO:0010468,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0044087,GO:0044089,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090070,GO:2000232,GO:2000234 - ko:K02906 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L3 NFINBLID_01552 1046629.Ssal_00085 2.13e-135 384.0 COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,4HB01@91061|Bacilli 91061|Bacilli J Forms part of the polypeptide exit tunnel rplD GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02926 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L4 NFINBLID_01553 264199.stu1932 6e-60 185.0 COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,4HKCV@91061|Bacilli 91061|Bacilli J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome rplW GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02892 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L23 NFINBLID_01554 1046629.Ssal_00087 5.06e-196 543.0 COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,4HAE8@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity rplB GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02886 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L2,Ribosomal_L2_C NFINBLID_01555 1000570.HMPREF9966_1567 8.13e-62 189.0 COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,4HIG0@91061|Bacilli,42DQ5@671232|Streptococcus anginosus group 91061|Bacilli J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA rpsS GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - ko:K02965 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S19 NFINBLID_01556 1046629.Ssal_00089 1.21e-71 216.0 COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,4HIK2@91061|Bacilli 91061|Bacilli J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome rplV GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02890 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L22 NFINBLID_01557 1046629.Ssal_00090 9.44e-153 429.0 COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,4HAUR@91061|Bacilli 91061|Bacilli J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation rpsC GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02982 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KH_2,Ribosomal_S3_C NFINBLID_01558 1046629.Ssal_00091 4.35e-94 274.0 COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,4HFPN@91061|Bacilli 91061|Bacilli J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs rplP GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02878 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L16 NFINBLID_01559 1046629.Ssal_00092 6.2e-35 119.0 COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,4HNUP@91061|Bacilli 91061|Bacilli J Belongs to the universal ribosomal protein uL29 family rpmC GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02904 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L29 NFINBLID_01560 1046629.Ssal_00093 3.08e-52 164.0 COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,4HKDN@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA rpsQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02961 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S17 NFINBLID_01561 1046629.Ssal_00094 2.55e-79 236.0 COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,4HGYR@91061|Bacilli 91061|Bacilli J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome rplN GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - ko:K02874 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L14 NFINBLID_01562 1046629.Ssal_00095 5.67e-64 195.0 COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,4HKH9@91061|Bacilli 91061|Bacilli J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit rplX GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02895 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - KOW,ribosomal_L24 NFINBLID_01563 1046629.Ssal_00096 5.86e-122 348.0 COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,4HBAX@91061|Bacilli 91061|Bacilli J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits rplE GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02931 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L5,Ribosomal_L5_C NFINBLID_01564 1000570.HMPREF9966_1576 2.03e-39 130.0 COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,4HNKX@91061|Bacilli,42EG0@671232|Streptococcus anginosus group 91061|Bacilli J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site rpsN - - ko:K02954 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S14 NFINBLID_01565 1046629.Ssal_00098 3.78e-88 259.0 COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,4HH32@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit rpsH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02994 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S8 NFINBLID_01566 1046629.Ssal_00099 5.88e-121 345.0 COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,4HFQD@91061|Bacilli 91061|Bacilli J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center rplF GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02933 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L6 NFINBLID_01567 1046629.Ssal_00100 7.15e-75 224.0 COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,4HIGF@91061|Bacilli 91061|Bacilli J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance rplR GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - ko:K02881 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L18p NFINBLID_01568 1046629.Ssal_00101 7e-104 301.0 COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,4HFN4@91061|Bacilli 91061|Bacilli J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body rpsE GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02988 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S5,Ribosomal_S5_C NFINBLID_01569 1046629.Ssal_00102 9.89e-33 113.0 COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,4HNHF@91061|Bacilli 91061|Bacilli J ribosomal protein l30 rpmD GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02907 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L30 NFINBLID_01570 1046629.Ssal_00103 8.47e-85 251.0 COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,4HFPW@91061|Bacilli 91061|Bacilli J binds to the 23S rRNA rplO GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02876 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27A NFINBLID_01571 1046629.Ssal_00104 8.65e-293 801.0 COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,4HAWH@91061|Bacilli 91061|Bacilli U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently secY GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5 - - SecY NFINBLID_01572 904306.HMPREF9192_1977 9.83e-148 416.0 COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,4HA89@91061|Bacilli 91061|Bacilli F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism adk GO:0003674,GO:0003824,GO:0004017,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 M00049 R00127,R01547,R11319 RC00002 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ADK,ADK_lid NFINBLID_01573 1046629.Ssal_00106 6.91e-45 145.0 COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,4HKF4@91061|Bacilli 91061|Bacilli J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex infA GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - ko:K02518 - - - - ko00000,ko03012 - - - eIF-1a NFINBLID_01574 1123301.KB904201_gene1724 3.26e-22 85.5 COG0257@1|root,COG0257@2|Bacteria 2|Bacteria J Belongs to the bacterial ribosomal protein bL36 family rpmJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02919 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L36 NFINBLID_01575 1046629.Ssal_00108 4.42e-75 225.0 COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,4HGX6@91061|Bacilli 91061|Bacilli J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits rpsM GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02952 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S13 NFINBLID_01576 1046629.Ssal_00109 1.63e-82 244.0 COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,4HH2T@91061|Bacilli 91061|Bacilli J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome rpsK GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02948 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S11 NFINBLID_01577 1046629.Ssal_00110 7.63e-220 607.0 COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,4H9R1@91061|Bacilli 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoA GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L NFINBLID_01578 1046629.Ssal_00111 3.03e-83 246.0 COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,4HGX2@91061|Bacilli 91061|Bacilli J ribosomal protein l17 rplQ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02879 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L17 NFINBLID_01579 1046629.Ssal_00112 8.68e-316 859.0 COG3572@1|root,COG3572@2|Bacteria,1TW3D@1239|Firmicutes,4HTV4@91061|Bacilli 91061|Bacilli H gamma-glutamylcysteine synthetase - - - - - - - - - - - - GCS2 NFINBLID_01581 1046629.Ssal_00114 8.52e-212 585.0 COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,4H9ZU@91061|Bacilli 91061|Bacilli G aldolase fba - 4.1.2.13,4.1.2.29 ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00003,M00165,M00167,M00344,M00345 R01068,R01070,R01829,R02568,R05378 RC00438,RC00439,RC00603,RC00604,RC00721 ko00000,ko00001,ko00002,ko01000 - - - F_bP_aldolase NFINBLID_01584 1046629.Ssal_00117 1.37e-123 353.0 COG4475@1|root,COG4475@2|Bacteria,1V3H0@1239|Firmicutes,4HH6F@91061|Bacilli 91061|Bacilli S Belongs to the UPF0340 family ywlG - - - - - - - - - - - DUF436 NFINBLID_01585 1046629.Ssal_00118 1.05e-163 458.0 COG2188@1|root,COG2188@2|Bacteria,1TRF6@1239|Firmicutes,4HDCX@91061|Bacilli 91061|Bacilli K trehalose operon treR - - ko:K03486 - - - - ko00000,ko03000 - - - GntR,UTRA NFINBLID_01586 1046629.Ssal_00119 0.0 1264.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system treP - 2.7.1.201 ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 M00270 R02780 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.13,4.A.1.2.4,4.A.1.2.8 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NFINBLID_01587 1046629.Ssal_00120 0.0 1099.0 COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,4HA1G@91061|Bacilli 91061|Bacilli G COG0366 Glycosidases treC - 3.2.1.93 ko:K01226 ko00500,map00500 - R00837,R06113 RC00049 ko00000,ko00001,ko01000 - GH13 - Alpha-amylase,DUF3459,Malt_amylase_C NFINBLID_01588 1046629.Ssal_00121 0.0 1252.0 COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,4HDSF@91061|Bacilli 91061|Bacilli O Peptidase family M13 pepO - - ko:K07386 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M13,Peptidase_M13_N NFINBLID_01589 904306.HMPREF9192_1994 0.0 1667.0 COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,4HAN8@91061|Bacilli 91061|Bacilli C belongs to the iron- containing alcohol dehydrogenase family adh - 1.1.1.1,1.2.1.10 ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 - R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927 RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195 ko00000,ko00001,ko01000 - - iSB619.SA_RS00885 Aldedh,Fe-ADH NFINBLID_01591 435842.HMPREF0848_01381 6.92e-05 52.8 COG3064@1|root,COG3064@2|Bacteria,1VK5M@1239|Firmicutes,4HS44@91061|Bacilli 91061|Bacilli M Membrane yebC - - - - - - - - - - - zf-ribbon_3,zinc_ribbon_2 NFINBLID_01592 1046629.Ssal_00127 0.0 954.0 COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,4H9R7@91061|Bacilli 91061|Bacilli E Threonine synthase thrC - 4.2.3.1 ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 M00018 R01466,R05086 RC00017,RC00526 ko00000,ko00001,ko00002,ko01000 - - - PALP,Thr_synth_N NFINBLID_01593 1046629.Ssal_00128 1.64e-284 780.0 COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,4H9Y2@91061|Bacilli 91061|Bacilli V Mate efflux family protein norN - - - - - - - - - - - MatE NFINBLID_01594 1046629.Ssal_00129 1.87e-76 228.0 COG1302@1|root,COG1302@2|Bacteria,1V3Q6@1239|Firmicutes,4HHYJ@91061|Bacilli 91061|Bacilli S cog cog1302 asp - - - - - - - - - - - Asp23 NFINBLID_01595 1046629.Ssal_00130 0.0 1049.0 COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,4HBSE@91061|Bacilli 91061|Bacilli S kinase related to dihydroxyacetone kinase yloV - - ko:K07030 - - - - ko00000 - - - Dak1_2,Dak2 NFINBLID_01596 1046629.Ssal_00131 0.0 1122.0 COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,4H9ZG@91061|Bacilli 91061|Bacilli E Belongs to the IlvD Edd family ilvD - 4.2.1.9 ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R01209,R04441,R05070 RC00468,RC01714 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ILVD_EDD NFINBLID_01597 1046629.Ssal_00132 0.0 1095.0 COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,4H9VR@91061|Bacilli 91061|Bacilli EH Acetolactate synthase ilvB - 2.2.1.6 ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - iYO844.BSU28310 TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N NFINBLID_01598 904306.HMPREF9192_2002 7.09e-101 293.0 COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,4HDY5@91061|Bacilli 91061|Bacilli E Acetolactate synthase ilvN GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 M00019,M00570,M00582 R00006,R00014,R00226,R03050,R04672,R04673,R08648 RC00027,RC00106,RC01192,RC02744,RC02893 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35 - - ACT,ACT_5,ALS_ss_C NFINBLID_01599 322159.STER_1848 1.73e-246 676.0 COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,4HADK@91061|Bacilli 91061|Bacilli H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate ilvC - 1.1.1.86 ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 M00019,M00570 R03051,R04439,R04440,R05068,R05069,R05071 RC00726,RC00836,RC00837,RC01726 ko00000,ko00001,ko00002,ko01000 - - - IlvC,IlvN NFINBLID_01600 904306.HMPREF9192_2004 9.54e-304 828.0 COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,4H9YV@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) tyrS GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 ko:K01866 ko00970,map00970 M00359,M00360 R02918 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 - - - S4,tRNA-synt_1b NFINBLID_01601 1046629.Ssal_00136 0.0 1530.0 COG0744@1|root,COG0744@2|Bacteria,1TPM5@1239|Firmicutes,4H9SA@91061|Bacilli 91061|Bacilli M penicillin-binding protein pbp1B - 2.4.1.129 ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01003,ko01011 - GT51 - Transgly,Transpeptidase NFINBLID_01602 1046629.Ssal_00138 0.0 2332.0 COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,4H9PK@91061|Bacilli 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoB GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7 NFINBLID_01603 904306.HMPREF9192_2007 0.0 2378.0 COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,4HA24@91061|Bacilli 91061|Bacilli K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates rpoC GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 M00183 R00435,R00441,R00442,R00443 RC02795 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 - - - RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5 NFINBLID_01604 1046629.Ssal_00141 1.37e-91 266.0 COG4699@1|root,COG4699@2|Bacteria,1VHC7@1239|Firmicutes,4HS15@91061|Bacilli 91061|Bacilli S cog cog4699 - - - - - - - - - - - - DUF1033 NFINBLID_01605 1046629.Ssal_00142 3.65e-223 615.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli 91061|Bacilli NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE NFINBLID_01606 904306.HMPREF9192_2011 2.98e-178 512.0 COG1459@1|root,COG2804@1|root,COG1459@2|Bacteria,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli 91061|Bacilli NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE NFINBLID_01607 1046629.Ssal_00144 1.1e-62 192.0 COG4537@1|root,COG4537@2|Bacteria,1VFI9@1239|Firmicutes,4HNNT@91061|Bacilli 91061|Bacilli U Required for transformation and DNA binding comGC GO:0005575,GO:0005623,GO:0005886,GO:0009986,GO:0016020,GO:0044464,GO:0071944 - ko:K02245 - M00429 - - ko00000,ko00002,ko02044 - - - N_methyl NFINBLID_01608 904306.HMPREF9192_2013 2.45e-88 260.0 COG2165@1|root,33A38@2|Bacteria,1VPGT@1239|Firmicutes,4HRZ0@91061|Bacilli 91061|Bacilli NU Competence protein cglD - - ko:K02246 - M00429 - - ko00000,ko00002,ko02044 - - - - NFINBLID_01609 873449.STRCR_0577 3.71e-23 91.3 COG2165@1|root,2ZS6J@2|Bacteria,1W385@1239|Firmicutes 1239|Firmicutes NU Type II secretory pathway pseudopilin - - - - - - - - - - - - PulG NFINBLID_01610 1046629.Ssal_00147 7.62e-92 269.0 COG4940@1|root,COG4940@2|Bacteria,1VKRP@1239|Firmicutes,4HR6S@91061|Bacilli 91061|Bacilli U Competence protein ComGF comGF - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF,N_methyl NFINBLID_01611 1198676.SMUGS5_08910 7.17e-17 80.5 COG4940@1|root,COG4940@2|Bacteria,1VJKM@1239|Firmicutes,4HQDT@91061|Bacilli 91061|Bacilli U Putative Competence protein ComGF - - - ko:K02248 - M00429 - - ko00000,ko00002,ko02044 - - - ComGF,N_methyl NFINBLID_01612 904306.HMPREF9192_2017 9.71e-226 622.0 COG0827@1|root,COG0827@2|Bacteria,1TRIQ@1239|Firmicutes,4H9SE@91061|Bacilli 91061|Bacilli L DNA methylase ytxK - 2.1.1.72 ko:K00571 - - - - ko00000,ko01000,ko02048 - - - N6_Mtase NFINBLID_01613 904306.HMPREF9192_2018 1.64e-282 772.0 COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,4HA7K@91061|Bacilli 91061|Bacilli F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction ackA - 2.7.2.1 ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 M00357,M00579 R00315,R01353 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - Acetate_kinase NFINBLID_01614 1046629.Ssal_00151 1.05e-36 124.0 COG1476@1|root,COG1476@2|Bacteria 2|Bacteria K sequence-specific DNA binding lanR - - ko:K07729 - - - - ko00000,ko03000 - - - HTH_3 NFINBLID_01615 1046629.Ssal_00152 2e-134 383.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi NFINBLID_01617 264199.stu1853 3.44e-120 347.0 COG1266@1|root,COG1266@2|Bacteria,1VEE2@1239|Firmicutes,4HP4A@91061|Bacilli 91061|Bacilli S CAAX amino terminal protease family protein - - - ko:K07052 - - - - ko00000 - - - Abi NFINBLID_01618 904306.HMPREF9192_2022 4.56e-168 471.0 COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,4HCBY@91061|Bacilli 91061|Bacilli E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline proC - 1.5.1.2 ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 M00015 R01248,R01251,R03291,R03293 RC00054,RC00083 ko00000,ko00001,ko00002,ko01000 - - - F420_oxidored,P5CR_dimer NFINBLID_01619 1046629.Ssal_00156 6.14e-259 709.0 COG1363@1|root,COG1363@2|Bacteria,1TNZT@1239|Firmicutes,4H9SM@91061|Bacilli 91061|Bacilli G COG1363 Cellulase M and related proteins pepA - 3.4.11.7 ko:K01261,ko:K01269 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M42 NFINBLID_01621 1046629.Ssal_00158 2.86e-72 216.0 COG0526@1|root,COG0526@2|Bacteria,1VAS6@1239|Firmicutes,4HKGM@91061|Bacilli 91061|Bacilli CO Thioredoxin ytpP GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - - - - - - - - - - Thioredoxin NFINBLID_01623 1046629.Ssal_00160 1.3e-145 410.0 COG0073@1|root,COG0073@2|Bacteria,1V7QA@1239|Firmicutes,4HJBD@91061|Bacilli 91061|Bacilli J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily XK27_10290 - - ko:K06878 - - - - ko00000 - - - DUF4479,tRNA_bind NFINBLID_01624 322159.STER_1823 1.72e-243 669.0 COG2391@1|root,COG2391@2|Bacteria,1TSNG@1239|Firmicutes,4HDN0@91061|Bacilli 91061|Bacilli S Sulphur transport yeeE - - ko:K07112 - - - - ko00000 - - - Sulf_transp NFINBLID_01625 322159.STER_1822 3.2e-49 156.0 COG0425@1|root,COG0425@2|Bacteria 2|Bacteria O sulfur carrier activity yeeD GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - ko:K07112 - - - - ko00000 - - - Sulf_transp,TusA NFINBLID_01626 322159.STER_1821 4.45e-86 253.0 COG0629@1|root,COG0629@2|Bacteria,1VXMZ@1239|Firmicutes,4HXCW@91061|Bacilli 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB NFINBLID_01627 1046629.Ssal_00164 1.34e-114 329.0 COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,4HH7S@91061|Bacilli 91061|Bacilli FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) tadA GO:0002097,GO:0002100,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 ko:K11991 - - R10223 RC00477 ko00000,ko01000,ko03016 - - - MafB19-deam NFINBLID_01631 1046629.Ssal_00168 1.51e-198 550.0 COG0500@1|root,COG2226@2|Bacteria 2|Bacteria Q methyltransferase rrmA - 2.1.1.187 ko:K00563,ko:K10947 - - R07233 RC00003 ko00000,ko01000,ko03000,ko03009 - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 NFINBLID_01632 1046629.Ssal_00169 5.1e-162 455.0 COG0546@1|root,COG0546@2|Bacteria,1V73N@1239|Firmicutes,4IU82@91061|Bacilli 91061|Bacilli S HAD hydrolase, family IA, variant - - - ko:K07025 - - - - ko00000 - - - HAD_2 NFINBLID_01633 1046629.Ssal_00170 1.77e-108 318.0 COG2171@1|root,COG2171@2|Bacteria,1TQUJ@1239|Firmicutes,4H9KY@91061|Bacilli 91061|Bacilli E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate dapH - 2.3.1.117,2.3.1.89 ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 M00016,M00525 R04364,R04365 RC00004,RC01136 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU14180 DapH_N,Hexapep NFINBLID_01634 1046629.Ssal_00172 1.82e-278 760.0 COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,4H9SG@91061|Bacilli 91061|Bacilli E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate hipO GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0050118,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.47 ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 M00525 R02733 RC00064,RC00300 ko00000,ko00001,ko00002,ko01000,ko01002 - - - M20_dimer,Peptidase_M20 NFINBLID_01635 904306.HMPREF9192_2039 8.09e-122 347.0 COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,4HM35@91061|Bacilli 91061|Bacilli H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family fthC GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0030272,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 ko:K01934 ko00670,ko01100,map00670,map01100 - R02301 RC00183 ko00000,ko00001,ko01000 - - - 5-FTHF_cyc-lig NFINBLID_01636 904306.HMPREF9192_2040 5.18e-149 420.0 COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,4HCDF@91061|Bacilli 91061|Bacilli O membrane protein (homolog of Drosophila rhomboid) gluP - 3.4.21.105 ko:K19225 - - - - ko00000,ko01000,ko01002 - - - Rhomboid,TPR_2,TPR_8 NFINBLID_01637 904306.HMPREF9192_2041 1.08e-215 595.0 COG1210@1|root,COG1210@2|Bacteria,1TQ24@1239|Firmicutes,4HATY@91061|Bacilli 91061|Bacilli M UTP-glucose-1-phosphate uridylyltransferase galU - 2.7.7.9 ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 M00129,M00361,M00362,M00549 R00289 RC00002 ko00000,ko00001,ko00002,ko01000 - - - NTP_transferase NFINBLID_01638 1046629.Ssal_00176 1.34e-232 642.0 COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,4HAXW@91061|Bacilli 91061|Bacilli I Glycerol-3-phosphate dehydrogenase gpsA GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 ko:K00057 ko00564,ko01110,map00564,map01110 - R00842,R00844 RC00029 ko00000,ko00001,ko01000 - - - NAD_Gly3P_dh_C,NAD_Gly3P_dh_N NFINBLID_01639 1046629.Ssal_00177 5.12e-124 354.0 2BY0N@1|root,321KG@2|Bacteria 2|Bacteria S Psort location CytoplasmicMembrane, score XK27_08585 - - ko:K16926 - M00582 - - ko00000,ko00002,ko02000 3.A.1.31 - - Trep_Strep NFINBLID_01640 1046629.Ssal_00179 1.49e-181 506.0 COG2116@1|root,COG2116@2|Bacteria,1V164@1239|Firmicutes,4HFJC@91061|Bacilli 91061|Bacilli P Formate nitrite transporter nirC_1 - - - - - - - - - - - Form_Nir_trans NFINBLID_01641 1046629.Ssal_00180 3.61e-307 836.0 COG0431@1|root,COG2461@1|root,COG0431@2|Bacteria,COG2461@2|Bacteria,1TPRA@1239|Firmicutes,4HDA5@91061|Bacilli 91061|Bacilli C reductase XK27_09615 - - ko:K19784 - - - - ko00000 - - - FMN_red,PAS_10 NFINBLID_01642 1046629.Ssal_00181 3.33e-140 396.0 COG0431@1|root,COG0431@2|Bacteria 2|Bacteria S FMN reductase (NADPH) activity XK27_09620 - - - - - - - - - - - FMN_red NFINBLID_01643 264199.stu1824 3.21e-99 288.0 COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,4HIZ3@91061|Bacilli 91061|Bacilli F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA dut - 3.6.1.23 ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 M00053 R02100,R11896 RC00002 ko00000,ko00001,ko00002,ko01000,ko03400 - - - dUTPase NFINBLID_01644 1095738.HMPREF1047_1312 2.21e-98 286.0 COG1335@1|root,COG1335@2|Bacteria 2|Bacteria Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - 3.5.1.19 ko:K08281 ko00760,ko01100,map00760,map01100 - R01268 RC00100 ko00000,ko00001,ko01000 - - - Isochorismatase NFINBLID_01645 1046629.Ssal_00184 3.73e-285 780.0 COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,4H9YC@91061|Bacilli 91061|Bacilli O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function radA - - ko:K04485 - - - - ko00000,ko03400 - - - AAA_25,ATPase,ChlI NFINBLID_01646 1046629.Ssal_00185 2.4e-162 454.0 COG2013@1|root,COG2013@2|Bacteria,1V6BD@1239|Firmicutes,4HIAR@91061|Bacilli 91061|Bacilli S Mitochondrial biogenesis AIM24 - - - - - - - - - - - - AIM24 NFINBLID_01647 1046629.Ssal_00186 7.91e-115 329.0 COG0288@1|root,COG0288@2|Bacteria,1V0TA@1239|Firmicutes,4HB9V@91061|Bacilli 91061|Bacilli P Reversible hydration of carbon dioxide cah - 4.2.1.1 ko:K01673 ko00910,map00910 - R00132,R10092 RC02807 ko00000,ko00001,ko01000 - - - Pro_CA NFINBLID_01648 1046629.Ssal_00187 4.66e-66 202.0 2DSU9@1|root,33HF9@2|Bacteria,1VNK9@1239|Firmicutes 1239|Firmicutes S Protein of unknown function (DUF3397) - - - - - - - - - - - - DUF3397 NFINBLID_01649 1046629.Ssal_00188 1.69e-93 273.0 COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,4HFQ0@91061|Bacilli 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors rplK GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02867 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L11,Ribosomal_L11_N NFINBLID_01650 1046629.Ssal_00189 1.37e-155 438.0 COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,4HAK4@91061|Bacilli 91061|Bacilli J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release rplA GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02863 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L1 NFINBLID_01651 1046629.Ssal_00190 0.0 1257.0 COG4166@1|root,COG4166@2|Bacteria,1TQVS@1239|Firmicutes,4HCCB@91061|Bacilli 91061|Bacilli E ABC transporter, substrate-binding protein, family 5 amiA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - SBP_bac_5 NFINBLID_01652 1046629.Ssal_00191 0.0 947.0 COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,4HAKH@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) gltX GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0009986,GO:0030246,GO:0030247,GO:0044464,GO:2001065 6.1.1.24 ko:K09698 ko00970,ko01100,map00970,map01100 M00360 R03651,R05578 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - iSB619.SA_RS02860 tRNA-synt_1c NFINBLID_01653 1046629.Ssal_00192 1.18e-292 801.0 COG3290@1|root,COG3290@2|Bacteria,1UYTM@1239|Firmicutes,4IPJ9@91061|Bacilli 91061|Bacilli T signal transduction protein with a C-terminal ATPase domain - - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5 NFINBLID_01654 1046629.Ssal_00193 2.1e-193 538.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity hpk9 - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 NFINBLID_01655 435842.HMPREF0848_01856 2.11e-263 726.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity hpk9 - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 NFINBLID_01656 1046629.Ssal_00195 2.93e-283 778.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity fasC - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 NFINBLID_01657 435842.HMPREF0848_01858 9.29e-168 469.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes,4HHAI@91061|Bacilli 91061|Bacilli KT Response regulator of the LytR AlgR family fasA - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg NFINBLID_01658 1046629.Ssal_00198 2.89e-293 800.0 COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,4HA1E@91061|Bacilli 91061|Bacilli E Belongs to the argininosuccinate synthase family. Type 1 subfamily argG GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 M00029,M00844,M00845 R01954 RC00380,RC00629 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04675 Arginosuc_synth NFINBLID_01659 1046629.Ssal_00199 0.0 909.0 COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,4HB24@91061|Bacilli 91061|Bacilli E Argininosuccinate lyase argH GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 M00029,M00844,M00845 R01086 RC00445,RC00447 ko00000,ko00001,ko00002,ko01000,ko04147 - - - ASL_C2,Lyase_1 NFINBLID_01660 264199.stu1811 9.69e-72 216.0 COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,4HKG6@91061|Bacilli 91061|Bacilli J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme rnpA GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 ko:K03536 - - - - ko00000,ko01000,ko03016 - - - Ribonuclease_P NFINBLID_01661 904306.HMPREF9192_2062 2.45e-186 520.0 COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,4HB3J@91061|Bacilli 91061|Bacilli U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins yidC GO:0005575,GO:0008150,GO:0009653,GO:0009987,GO:0016020,GO:0030154,GO:0030435,GO:0032502,GO:0043934,GO:0048646,GO:0048856,GO:0048869 - ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044,ko03029 2.A.9 - - 60KD_IMP NFINBLID_01662 1046629.Ssal_00202 5.32e-201 562.0 COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,4HHHU@91061|Bacilli 91061|Bacilli S RNA-binding protein jag - - ko:K06346 - - - - ko00000 - - - Jag_N,KH_4,R3H NFINBLID_01663 1046629.Ssal_00203 1.81e-133 379.0 COG1309@1|root,COG1309@2|Bacteria,1V0VT@1239|Firmicutes,4HPD3@91061|Bacilli 91061|Bacilli K Transcriptional regulator - - - - - - - - - - - - TetR_N,WHG NFINBLID_01664 1046629.Ssal_00204 2.57e-133 377.0 COG2249@1|root,COG2249@2|Bacteria,1V59U@1239|Firmicutes,4HHZC@91061|Bacilli 91061|Bacilli S NADPH-quinone reductase (modulator of drug activity B) - - 1.6.5.2 ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 - R02964,R03643,R03816 RC00819 ko00000,ko00001,ko01000 - - - Flavodoxin_2 NFINBLID_01665 1046629.Ssal_00205 4.62e-20 80.5 COG0230@1|root,COG0230@2|Bacteria 2|Bacteria J Ribosomal protein L34 rpmH GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02914 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L34 NFINBLID_01666 1046629.Ssal_00206 5.73e-288 785.0 COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,4HCNM@91061|Bacilli 91061|Bacilli F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) tgt GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 ko:K00773 - - R03789,R10209 RC00063 ko00000,ko01000,ko03016 - - - TGT NFINBLID_01667 1410632.JHWW01000005_gene774 4.61e-19 97.8 COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,27K2X@186928|unclassified Lachnospiraceae 186801|Clostridia M Psort location Cytoplasmic, score - - - - - - - - - - - - Mob_Pre NFINBLID_01669 264199.stu0537 6.49e-65 199.0 COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,4HIGQ@91061|Bacilli 91061|Bacilli J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation rplL - - ko:K02935 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L12,Ribosomal_L12_N NFINBLID_01670 435842.HMPREF0848_00164 1.7e-101 295.0 COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,4HH0N@91061|Bacilli 91061|Bacilli J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors rplJ GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02864 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L10 NFINBLID_01671 435842.HMPREF0848_00163 1.95e-272 747.0 COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,4HF9U@91061|Bacilli 91061|Bacilli V permease protein - - - ko:K02004 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - FtsX,MacB_PCD NFINBLID_01672 904306.HMPREF9192_0440 6.54e-157 441.0 COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,4HBMF@91061|Bacilli 91061|Bacilli V ABC transporter, ATP-binding protein salX - - ko:K02003 - M00258 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_01673 435842.HMPREF0848_00161 5.98e-247 684.0 COG0845@1|root,COG0845@2|Bacteria,1VBR9@1239|Firmicutes,4HG5X@91061|Bacilli 91061|Bacilli M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - ko:K02005 - - - - ko00000 - - - Biotin_lipoyl_2,HlyD_D23 NFINBLID_01674 435842.HMPREF0848_00160 1.01e-155 439.0 COG2265@1|root,COG2265@2|Bacteria,1V4AQ@1239|Firmicutes,4HHBA@91061|Bacilli 91061|Bacilli J Putative SAM-dependent methyltransferase - - - - - - - - - - - - SAM_MT NFINBLID_01675 904306.HMPREF9192_0437 0.0 2051.0 COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,4HAEY@91061|Bacilli 91061|Bacilli F carbamoyl-phosphate synthetase ammonia chain carB GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_L_D2,CPSase_L_D3,MGS NFINBLID_01676 1046629.Ssal_01640 1.86e-268 734.0 COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,4H9Z0@91061|Bacilli 91061|Bacilli F carbamoyl-phosphate synthetase glutamine chain carA GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R00256,R00575,R01395,R10948,R10949 RC00002,RC00010,RC00043,RC02750,RC02798,RC03314 ko00000,ko00001,ko00002,ko01000 - - - CPSase_sm_chain,GATase NFINBLID_01677 1046629.Ssal_01641 6.8e-221 609.0 COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,4H9M6@91061|Bacilli 91061|Bacilli F Belongs to the ATCase OTCase family pyrB GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 M00051 R01397 RC00064,RC02850 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU15490 OTCace,OTCace_N NFINBLID_01678 1046629.Ssal_01642 1.16e-280 769.0 COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,4HAEU@91061|Bacilli 91061|Bacilli F uracil Permease pyrP - - ko:K02824 - - - - ko00000,ko02000 2.A.40.1.1,2.A.40.1.2 - - Xan_ur_permease NFINBLID_01679 1046629.Ssal_01644 5.91e-114 327.0 COG2065@1|root,COG2065@2|Bacteria,1V3GV@1239|Firmicutes,4HGYE@91061|Bacilli 91061|Bacilli F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant pyrR GO:0003674,GO:0003700,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 ko:K02825 ko00240,ko01100,map00240,map01100 - R00966 RC00063 ko00000,ko00001,ko01000,ko03000 - - - Pribosyltran NFINBLID_01680 435842.HMPREF0848_00153 2.52e-208 576.0 COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,4HBG2@91061|Bacilli 91061|Bacilli J Responsible for synthesis of pseudouridine from uracil rluD GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 ko:K06180 - - - - ko00000,ko01000,ko03009 - - - PseudoU_synth_2,S4 NFINBLID_01681 435842.HMPREF0848_00152 1.54e-98 287.0 COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,4HIR4@91061|Bacilli 91061|Bacilli MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins lspA GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 ko:K03101 ko03060,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_A8 NFINBLID_01682 1046629.Ssal_01647 9.98e-215 593.0 COG0583@1|root,COG0583@2|Bacteria,1V53I@1239|Firmicutes,4HIEU@91061|Bacilli 91061|Bacilli K transcriptional regulator (lysR family) lysR - - - - - - - - - - - HTH_1,LysR_substrate NFINBLID_01684 1046629.Ssal_01001 1.08e-125 359.0 2FFHU@1|root,347FA@2|Bacteria,1W0N0@1239|Firmicutes,4HZDI@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01685 862967.SIR_0145 1.12e-71 226.0 COG0842@1|root,COG0842@2|Bacteria,1VGXQ@1239|Firmicutes,4ISBX@91061|Bacilli 91061|Bacilli V ABC-2 type transporter - - - - - - - - - - - - ABC2_membrane NFINBLID_01686 1046629.Ssal_00998 1.34e-201 559.0 COG1131@1|root,COG1131@2|Bacteria,1V5JQ@1239|Firmicutes,4HM69@91061|Bacilli 91061|Bacilli V AAA domain, putative AbiEii toxin, Type IV TA system - - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_01687 1302863.I872_07720 3.98e-09 56.6 COG5444@1|root,32YNG@2|Bacteria,1VJMI@1239|Firmicutes,4HPD8@91061|Bacilli 91061|Bacilli S Protein of unknown function, DUF600 - - - - - - - - - - - - DUF600 NFINBLID_01690 1046629.Ssal_01652 3.4e-177 494.0 COG0652@1|root,COG0652@2|Bacteria 2|Bacteria O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides ppiA - 5.2.1.8 ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 - - - ko00000,ko00001,ko01000,ko03110,ko04147 - - - Pro_isomerase NFINBLID_01691 1046629.Ssal_01653 0.0 1171.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system - - - ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 M00271 - - ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.11,4.A.1.2.2,4.A.1.2.5,4.A.1.2.6 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NFINBLID_01693 1046629.Ssal_01655 0.0 876.0 COG1113@1|root,COG1113@2|Bacteria,1TP97@1239|Firmicutes,4H9QX@91061|Bacilli 91061|Bacilli E permease cycA - - ko:K03293,ko:K11737 - - - - ko00000,ko02000 2.A.3.1,2.A.3.1.7 - - AA_permease NFINBLID_01694 1046629.Ssal_01656 1.17e-51 163.0 COG4224@1|root,COG4224@2|Bacteria,1VEKJ@1239|Firmicutes,4HNIB@91061|Bacilli 91061|Bacilli S UPF0291 protein ynzC - - - - - - - - - - - DUF896 NFINBLID_01695 1046629.Ssal_01657 0.0 1273.0 COG0751@1|root,COG0751@2|Bacteria,1TNZ7@1239|Firmicutes,4H9NT@91061|Bacilli 91061|Bacilli J Glycyl-tRNA synthetase beta subunit glyS - 6.1.1.14 ko:K01879 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DALR_1,tRNA_synt_2f NFINBLID_01696 1046629.Ssal_01658 1.23e-226 623.0 COG0752@1|root,COG0752@2|Bacteria,1TPW8@1239|Firmicutes,4HBCF@91061|Bacilli 91061|Bacilli J glycyl-tRNA synthetase alpha subunit glyQ - 6.1.1.14 ko:K01878 ko00970,map00970 M00360 R03654 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2e NFINBLID_01697 1046629.Ssal_01659 3.57e-281 770.0 COG3949@1|root,COG3949@2|Bacteria,1U601@1239|Firmicutes,4HBYW@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - - NFINBLID_01698 1046629.Ssal_01660 4.53e-267 732.0 COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,4HC6C@91061|Bacilli 91061|Bacilli G Belongs to the metallo-dependent hydrolases superfamily. NagA family nagA - 3.5.1.25 ko:K01443 ko00520,ko01130,map00520,map01130 - R02059 RC00166,RC00300 ko00000,ko00001,ko01000 - - - Amidohydro_1 NFINBLID_01699 1046629.Ssal_01661 0.0 1018.0 COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,4HAZ0@91061|Bacilli 91061|Bacilli P COG1283 Na phosphate symporter yjbB - - ko:K03324 - - - - ko00000,ko02000 2.A.58.2 - - Na_Pi_cotrans,PhoU NFINBLID_01700 1046629.Ssal_01662 3.29e-163 467.0 COG1705@1|root,COG1705@2|Bacteria 2|Bacteria NU amidase activity - - 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 - - - Amidase_3,CHAP,CW_binding_1,GBS_Bsp-like,Glucosaminidase,SH3_5 NFINBLID_01701 1046629.Ssal_01663 1.36e-105 306.0 2E80M@1|root,332EU@2|Bacteria,1VJ8N@1239|Firmicutes,4HZSS@91061|Bacilli 91061|Bacilli S Bacterial inner membrane protein - - - - - - - - - - - - Imp-YgjV NFINBLID_01702 1046629.Ssal_01664 3.32e-183 511.0 COG0561@1|root,COG0561@2|Bacteria,1VAFW@1239|Firmicutes,4HIFQ@91061|Bacilli 91061|Bacilli S Sucrose-6F-phosphate phosphohydrolase XK27_04800 - - - - - - - - - - - Hydrolase_3 NFINBLID_01703 1046629.Ssal_01665 2.52e-51 166.0 COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,4HK4Q@91061|Bacilli 91061|Bacilli S HD domain - - - ko:K07023 - - - - ko00000 - - - HD_3 NFINBLID_01704 1316408.HSISM1_2064 2.24e-50 164.0 COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,4HK4Q@91061|Bacilli 91061|Bacilli S HD domain - - - ko:K07023 - - - - ko00000 - - - HD_3 NFINBLID_01705 1046629.Ssal_01666 5.13e-137 389.0 COG1705@1|root,COG1705@2|Bacteria 2|Bacteria NU amidase activity mur1 - 3.4.17.14,3.5.1.28 ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 M00651,M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 - - - GBS_Bsp-like,Glucosaminidase,Rod-binding NFINBLID_01706 1046629.Ssal_01667 1.08e-69 211.0 COG0347@1|root,COG0347@2|Bacteria,1V9Z5@1239|Firmicutes,4HJ6Z@91061|Bacilli 91061|Bacilli K Belongs to the P(II) protein family glnB - - ko:K04751 ko02020,map02020 - - - ko00000,ko00001 - - - P-II NFINBLID_01707 365659.smi_0683 4.98e-291 795.0 COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,4HBGK@91061|Bacilli 91061|Bacilli P Ammonium Transporter amt - - ko:K03320 - - - - ko00000,ko02000 1.A.11 - - Ammonium_transp NFINBLID_01708 1046629.Ssal_01669 9.87e-204 564.0 COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,4HAH8@91061|Bacilli 91061|Bacilli H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA rsmI GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 ko:K07056 - - - - ko00000,ko01000,ko03009 - - - TP_methylase NFINBLID_01709 1046629.Ssal_01670 2e-73 219.0 COG4467@1|root,COG4467@2|Bacteria,1VA1F@1239|Firmicutes,4HKND@91061|Bacilli 91061|Bacilli L Involved in initiation control of chromosome replication yabA GO:0003674,GO:0005488,GO:0005515,GO:0042802 - - - - - - - - - - YabB NFINBLID_01710 1046629.Ssal_01671 4.74e-176 492.0 COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,4H9M9@91061|Bacilli 91061|Bacilli S stage 0 sporulation protein yaaT GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - - - - - - - - - - PSP1 NFINBLID_01711 904306.HMPREF9192_0406 5.07e-203 562.0 COG0470@1|root,COG0470@2|Bacteria,1TRVS@1239|Firmicutes,4HA3T@91061|Bacilli 91061|Bacilli L dna polymerase iii holB - 2.7.7.7 ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 - - - DNA_pol3_delta2,DNApol3-delta_C NFINBLID_01712 1046629.Ssal_01673 5.67e-141 399.0 COG0125@1|root,COG0125@2|Bacteria,1V1HE@1239|Firmicutes,4HGWR@91061|Bacilli 91061|Bacilli F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis tmk GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 ko:K00943 ko00240,ko01100,map00240,map01100 M00053 R02094,R02098 RC00002 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS02535 Thymidylate_kin NFINBLID_01714 435842.HMPREF0848_00124 0.0 1281.0 COG0021@1|root,COG0021@2|Bacteria,1TPIB@1239|Firmicutes,4HADA@91061|Bacilli 91061|Bacilli G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate tkt - 2.2.1.1 ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007,M00165,M00167 R01067,R01641,R01830,R06590 RC00032,RC00226,RC00571,RC01560 ko00000,ko00001,ko00002,ko01000 - - - Transket_pyr,Transketolase_C,Transketolase_N NFINBLID_01715 1046629.Ssal_01675 7.68e-174 485.0 COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,4HAPT@91061|Bacilli 91061|Bacilli G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) tpiA GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003 R01015 RC00423 ko00000,ko00001,ko00002,ko01000,ko04147 - - - TIM NFINBLID_01716 1046629.Ssal_01677 3.2e-285 779.0 COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,4HAEH@91061|Bacilli 91061|Bacilli J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis tuf GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009274,GO:0009275,GO:0009986,GO:0010339,GO:0016020,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035821,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - ko:K02358,ko:K15771 ko02010,map02010 M00491 - - ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 3.A.1.1.16,3.A.1.1.2 - - GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3 NFINBLID_01717 435842.HMPREF0848_00121 7.12e-278 763.0 COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,4HAEV@91061|Bacilli 91061|Bacilli D Belongs to the SEDS family ftsW - - ko:K03588 ko04112,map04112 - - - ko00000,ko00001,ko02000,ko03036 2.A.103.1 - - FTSW_RODA_SPOVE NFINBLID_01718 1046629.Ssal_01679 1.24e-89 263.0 COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,4HKHS@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane atpC GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_DE,ATP-synt_DE_N NFINBLID_01719 1046629.Ssal_01680 0.0 907.0 COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,4HAT6@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits atpD - 3.6.3.14 ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10965 ATP-synt_ab,ATP-synt_ab_N NFINBLID_01720 1046629.Ssal_01681 3.17e-202 560.0 COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,4HB0E@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex atpG - - ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iSB619.SA_RS10970,iYO844.BSU36820 ATP-synt NFINBLID_01721 904306.HMPREF9192_0397 0.0 962.0 COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,4HAMZ@91061|Bacilli 91061|Bacilli C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit atpA - 3.6.3.14 ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko01000 3.A.2.1 - iSB619.SA_RS10975 ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N NFINBLID_01722 1046629.Ssal_01683 8.62e-114 327.0 COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,4HKW1@91061|Bacilli 91061|Bacilli C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpH - - ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - OSCP NFINBLID_01723 1046629.Ssal_01684 1.78e-102 298.0 COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,4HM64@91061|Bacilli 91061|Bacilli C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) atpF - - ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - iYO844.BSU36850 ATP-synt_B NFINBLID_01724 1046629.Ssal_01685 4.97e-157 441.0 COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,4H9NV@91061|Bacilli 91061|Bacilli C it plays a direct role in the translocation of protons across the membrane atpB GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194,ko03110 3.A.2.1 - - ATP-synt_A NFINBLID_01725 1123298.KB904069_gene1213 1.44e-23 90.9 COG0636@1|root,2ZI0B@2|Bacteria 2|Bacteria C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation atpE GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 M00157 - - ko00000,ko00001,ko00002,ko00194 3.A.2.1 - - ATP-synt_C NFINBLID_01727 1046629.Ssal_00550 0.0 1751.0 COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,4HB85@91061|Bacilli 91061|Bacilli J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner valS GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 ko:K01873 ko00970,map00970 M00359,M00360 R03665 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1 NFINBLID_01728 1123315.AUIP01000008_gene724 1.17e-123 370.0 2CM4N@1|root,2ZBX7@2|Bacteria,1V209@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - NFINBLID_01729 997830.HMPREF1124_1771 5.57e-121 346.0 COG1670@1|root,COG1670@2|Bacteria,1V2C6@1239|Firmicutes,4HG3C@91061|Bacilli,43F7Y@68892|Streptococcus infantis 91061|Bacilli J Acetyltransferase (GNAT) domain - - - - - - - - - - - - Acetyltransf_3 NFINBLID_01730 435842.HMPREF0848_00106 1.01e-128 369.0 COG1853@1|root,COG1853@2|Bacteria,1VENC@1239|Firmicutes,4HQ31@91061|Bacilli 91061|Bacilli S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - - - - - - - - - - Flavin_Reduct NFINBLID_01731 1123314.AUIO01000005_gene141 1.99e-18 84.3 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA NFINBLID_01733 322159.STER_0508 1.65e-189 528.0 COG2962@1|root,COG2962@2|Bacteria,1TQF2@1239|Firmicutes,4HAYU@91061|Bacilli 91061|Bacilli S Transporter rarD - - ko:K05786 - - - - ko00000,ko02000 2.A.7.7 - - EamA NFINBLID_01734 1046629.Ssal_01693 1.01e-195 543.0 COG0083@1|root,COG0083@2|Bacteria,1TRWS@1239|Firmicutes,4HCQN@91061|Bacilli 91061|Bacilli E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate thrB GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 M00018 R01771 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06620 GHMP_kinases_C,GHMP_kinases_N NFINBLID_01735 1046629.Ssal_01694 2.44e-302 825.0 COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,4HBAP@91061|Bacilli 91061|Bacilli E homoserine dehydrogenase hom - 1.1.1.3 ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 M00017,M00018 R01773,R01775 RC00087 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS06610 ACT,Homoserine_dh,NAD_binding_3 NFINBLID_01736 1046629.Ssal_01695 2.01e-189 528.0 COG0726@1|root,COG0726@2|Bacteria,1V6AW@1239|Firmicutes,4HHC9@91061|Bacilli 91061|Bacilli G deacetylase icaB - - - - - - - - - - - Polysacc_deac_1 NFINBLID_01737 1046629.Ssal_01696 9.45e-260 713.0 COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,4H9VZ@91061|Bacilli 91061|Bacilli E acetylornithine aminotransferase argD GO:0003674,GO:0003824,GO:0003992,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17 ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00028,M00845 R02283,R04475 RC00006,RC00062 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_3 NFINBLID_01738 1046629.Ssal_01697 9.16e-158 444.0 COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes 1239|Firmicutes E Belongs to the acetylglutamate kinase family. ArgB subfamily argB GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R02649 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase NFINBLID_01739 435842.HMPREF0848_00097 3.86e-281 769.0 COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,4H9TQ@91061|Bacilli 91061|Bacilli E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate argJ GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028 R00259,R02282 RC00004,RC00064 ko00000,ko00001,ko00002,ko01000 - - - ArgJ NFINBLID_01740 1046629.Ssal_01699 1.7e-237 654.0 COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,4H9YD@91061|Bacilli 91061|Bacilli E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde argC GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 M00028,M00845 R03443 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU11190 Semialdhyde_dh,Semialdhyde_dhC NFINBLID_01741 1046629.Ssal_01700 1.46e-283 775.0 COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,4HAHQ@91061|Bacilli 91061|Bacilli E mutations do not affect methionine salvage in vivo however mtnE - - ko:K08969 ko00270,ko01100,map00270,map01100 M00034 R07396 RC00006 ko00000,ko00001,ko00002,ko01000,ko01007 - - - Aminotran_1_2 NFINBLID_01742 904306.HMPREF9192_0374 5.17e-176 491.0 COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,4HC44@91061|Bacilli 91061|Bacilli S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase mtnU - 3.5.1.3 ko:K13566 ko00250,map00250 - R00269,R00348 RC00010 ko00000,ko00001,ko01000 - - - CN_hydrolase NFINBLID_01743 904306.HMPREF9192_0370 0.0 2183.0 COG0739@1|root,COG0860@1|root,COG1705@1|root,COG1876@1|root,COG3757@1|root,COG0739@2|Bacteria,COG0860@2|Bacteria,COG1705@2|Bacteria,COG1876@2|Bacteria,COG3757@2|Bacteria,1V1F7@1239|Firmicutes,4ISN5@91061|Bacilli 91061|Bacilli M D-alanyl-D-alanine carboxypeptidase - - 3.4.17.14 ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 M00651 - - ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 - - - GBS_Bsp-like,SH3_5,VanY,YSIRK_signal NFINBLID_01745 1046629.Ssal_01708 1.38e-175 489.0 COG3279@1|root,COG3279@2|Bacteria,1V392@1239|Firmicutes 1239|Firmicutes KT response regulator - - - ko:K07707 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko02022 - - - LytTR,Response_reg NFINBLID_01746 1046629.Ssal_01709 0.0 1484.0 COG0860@1|root,COG1705@1|root,COG0860@2|Bacteria,COG1705@2|Bacteria,1W25V@1239|Firmicutes,4HGXW@91061|Bacilli 91061|Bacilli M GBS Bsp-like repeat - - - - - - - - - - - - GBS_Bsp-like,Peptidase_C70,SH3_5,YSIRK_signal NFINBLID_01747 1046629.Ssal_01730 0.0 1707.0 COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,4H9XC@91061|Bacilli 91061|Bacilli J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain alaS GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 ko:K01872 ko00970,map00970 M00359,M00360 R03038 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - DHHA1,tRNA-synt_2c,tRNA_SAD NFINBLID_01748 435842.HMPREF0848_00077 7.66e-111 318.0 COG4894@1|root,COG4894@2|Bacteria,1VBT3@1239|Firmicutes,4HH8W@91061|Bacilli 91061|Bacilli S LURP-one-related XK27_03390 - - - - - - - - - - - LOR NFINBLID_01749 1046629.Ssal_01733 4.58e-237 656.0 COG0760@1|root,COG0760@2|Bacteria 2|Bacteria O peptidyl-prolyl cis-trans isomerase activity prsA - 3.1.3.16,5.2.1.8 ko:K01802,ko:K03769,ko:K07533,ko:K20074 - - - - ko00000,ko01000,ko01009,ko03110 - - - Rotamase,Rotamase_2,SurA_N_3 NFINBLID_01750 1046629.Ssal_01734 5.91e-155 436.0 COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,4HE9E@91061|Bacilli 91061|Bacilli S O-Methyltransferase yrrM - 2.1.1.104 ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 M00039,M00350 R01942,R06578 RC00003,RC00392 ko00000,ko00001,ko00002,ko01000 - - - Methyltransf_3 NFINBLID_01751 904306.HMPREF9192_0364 4.09e-275 754.0 COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,4HB93@91061|Bacilli 91061|Bacilli P COG0477 Permeases of the major facilitator superfamily oxlT - - ko:K08177 - - - - ko00000,ko02000 2.A.1.11 - - MFS_1 NFINBLID_01752 1046629.Ssal_01736 0.0 1183.0 COG1164@1|root,COG1164@2|Bacteria,1TP4P@1239|Firmicutes,4HA7X@91061|Bacilli 91061|Bacilli E oligoendopeptidase F pepF GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - ko:K08602 - - - - ko00000,ko01000,ko01002 - - - Peptidase_M3,Peptidase_M3_N NFINBLID_01753 1046629.Ssal_01737 2.9e-207 575.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA NFINBLID_01754 1046629.Ssal_01741 0.0 1084.0 2DGEP@1|root,2ZVNT@2|Bacteria 2|Bacteria S Glucan-binding protein C - - - - - - - - - - - - GbpC,Gram_pos_anchor NFINBLID_01755 435842.HMPREF0848_00071 1.42e-134 385.0 COG1266@1|root,COG1266@2|Bacteria,1VCV8@1239|Firmicutes 1239|Firmicutes S CAAX amino terminal protease family protein - - - ko:K07052 - - - - ko00000 - - - Abi NFINBLID_01756 1046629.Ssal_01743 3.03e-215 594.0 COG0583@1|root,COG0583@2|Bacteria,1V53I@1239|Firmicutes,4HIEU@91061|Bacilli 91061|Bacilli K transcriptional regulator (lysR family) - - - - - - - - - - - - HTH_1,LysR_substrate NFINBLID_01757 435842.HMPREF0848_00069 3.72e-200 554.0 COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,4H9XJ@91061|Bacilli 91061|Bacilli S reductase - - 1.1.1.346 ko:K06221 - - R08878 RC00089 ko00000,ko01000 - - - Aldo_ket_red NFINBLID_01758 904306.HMPREF9192_0360 0.0 1325.0 COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,4H9VC@91061|Bacilli 91061|Bacilli J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation metG GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 ko:K01874 ko00450,ko00970,map00450,map00970 M00359,M00360 R03659,R04773 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - Anticodon_1,tRNA-synt_1g,tRNA_bind NFINBLID_01762 322159.STER_0480 5.69e-238 656.0 COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,4HBD5@91061|Bacilli 91061|Bacilli T phosphate starvation-inducible protein PhoH phoH - - ko:K06217 - - - - ko00000 - - - PhoH NFINBLID_01763 1046629.Ssal_01753 4.57e-205 578.0 COG1388@1|root,COG1388@2|Bacteria,1V61Q@1239|Firmicutes,4HHT0@91061|Bacilli 91061|Bacilli M LysM domain protein sip - - - - - - - - - - - LysM NFINBLID_01764 904306.HMPREF9192_0353 2.72e-46 148.0 COG4479@1|root,COG4479@2|Bacteria,1VFI4@1239|Firmicutes,4HR7P@91061|Bacilli 91061|Bacilli S Belongs to the UPF0346 family yozE - - - - - - - - - - - YozE_SAM_like NFINBLID_01765 1046629.Ssal_01755 4.92e-207 572.0 COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,4HDAZ@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria yitL - - ko:K00243 - - - - ko00000 - - - S1_2 NFINBLID_01766 904306.HMPREF9192_0351 7.89e-118 338.0 COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,4HFSH@91061|Bacilli 91061|Bacilli J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another frr GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - ko:K02838 - - - - ko00000,ko03012 - - - RRF NFINBLID_01767 1046629.Ssal_01757 2.78e-168 471.0 COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,4H9UB@91061|Bacilli 91061|Bacilli F Catalyzes the reversible phosphorylation of UMP to UDP pyrH - 2.7.4.22 ko:K09903 ko00240,ko01100,map00240,map01100 - R00158 RC00002 ko00000,ko00001,ko01000 - - iSB619.SA_RS06240 AA_kinase NFINBLID_01768 1046629.Ssal_01758 1.07e-267 736.0 COG0642@1|root,COG0642@2|Bacteria,1UHQH@1239|Firmicutes,4HAHG@91061|Bacilli 91061|Bacilli T Histidine kinase sptS - - - - - - - - - - - HATPase_c,HisKA NFINBLID_01769 1046629.Ssal_01760 1.67e-150 424.0 COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,4HG2E@91061|Bacilli 91061|Bacilli T response regulator dltr - - - - - - - - - - - Response_reg,Trans_reg_C NFINBLID_01770 1046629.Ssal_01761 2.07e-142 402.0 COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,4HTR5@91061|Bacilli 91061|Bacilli S Region found in RelA / SpoT proteins - - 2.7.6.5 ko:K00951 ko00230,map00230 - R00429 RC00002,RC00078 ko00000,ko00001,ko01000 - - - RelA_SpoT NFINBLID_01771 1046629.Ssal_01762 2.5e-141 399.0 COG0454@1|root,COG0456@2|Bacteria,1VF01@1239|Firmicutes,4HPKN@91061|Bacilli 91061|Bacilli K Acetyltransferase (GNAT) family - - - - - - - - - - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 NFINBLID_01772 1046629.Ssal_01763 0.0 1105.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein lmrA2 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NFINBLID_01773 1046629.Ssal_01764 0.0 1103.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein lmrA1 - - ko:K02021,ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21 - - ABC_membrane,ABC_tran NFINBLID_01774 435842.HMPREF0848_00049 6.75e-96 280.0 COG1846@1|root,COG1846@2|Bacteria 2|Bacteria K DNA-binding transcription factor activity - - - - - - - - - - - - HTH_27,MarR,MarR_2 NFINBLID_01775 1046629.Ssal_01766 5.52e-92 269.0 COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,4HGYC@91061|Bacilli 91061|Bacilli J Removes the formyl group from the N-terminal Met of newly synthesized proteins def_1 - 3.5.1.88 ko:K01462 - - - - ko00000,ko01000 - - - Pep_deformylase NFINBLID_01776 1046629.Ssal_01767 0.0 945.0 COG5617@1|root,COG5617@2|Bacteria,1VS0Z@1239|Firmicutes,4HJQE@91061|Bacilli 91061|Bacilli S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - - NFINBLID_01777 904306.HMPREF9192_0340 0.0 880.0 COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,4HAEI@91061|Bacilli 91061|Bacilli E Belongs to the Glu Leu Phe Val dehydrogenases family gdhA - 1.4.1.4 ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 - R00248 RC00006,RC02799 ko00000,ko00001,ko01000 - - - ELFV_dehydrog,ELFV_dehydrog_N NFINBLID_01778 1046629.Ssal_01769 3.62e-269 736.0 COG1057@1|root,COG3172@1|root,COG1057@2|Bacteria,COG3172@2|Bacteria,1TQ29@1239|Firmicutes,4HBZT@91061|Bacilli 91061|Bacilli H adenylyltransferase nadR - - - - - - - - - - - AAA_28,CTP_transf_like NFINBLID_01779 904306.HMPREF9192_0338 6e-167 468.0 COG1051@1|root,COG1051@2|Bacteria,1TST7@1239|Firmicutes,4HEFP@91061|Bacilli 91061|Bacilli F AdP-ribose pyrophosphatase - - - - - - - - - - - - NUDIX NFINBLID_01780 764298.STRMA_0561 6.23e-30 114.0 COG3247@1|root,COG3247@2|Bacteria,1VK2X@1239|Firmicutes 1239|Firmicutes S Short repeat of unknown function (DUF308) - - - - - - - - - - - - DUF308 NFINBLID_01781 1046629.Ssal_01772 0.0 1176.0 COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,4H9TK@91061|Bacilli 91061|Bacilli S abc transporter atp-binding protein yfmR - - ko:K15738 - - - - ko00000,ko02000 3.A.1.120.6 - - ABC_tran,ABC_tran_CTD,ABC_tran_Xtn NFINBLID_01782 904306.HMPREF9192_0334 3.15e-277 759.0 COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,4HB2W@91061|Bacilli 91061|Bacilli J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate cca - 2.7.7.72 ko:K00974 ko03013,map03013 - R09382,R09383,R09384,R09386 RC00078 ko00000,ko00001,ko01000,ko03016 - - - PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2 NFINBLID_01783 1046629.Ssal_01774 2.12e-177 494.0 COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,4HA5X@91061|Bacilli 91061|Bacilli E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate dapB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 M00016,M00525,M00526,M00527 R04198,R04199 RC00478 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU22490 DapB_C,DapB_N NFINBLID_01784 1046629.Ssal_01775 3.12e-187 521.0 COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,4HVKJ@91061|Bacilli 91061|Bacilli S EDD domain protein, DegV family - - - - - - - - - - - - DegV NFINBLID_01785 1046629.Ssal_01776 2.63e-82 243.0 COG4835@1|root,COG4835@2|Bacteria,1VHA6@1239|Firmicutes,4HPTC@91061|Bacilli 91061|Bacilli S cog cog4835 WQ51_03320 - - - - - - - - - - - DUF1149 NFINBLID_01786 322159.STER_0457 4.68e-169 471.0 COG1670@1|root,COG1670@2|Bacteria 2|Bacteria J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins ydaF_2 - - - - - - - - - - - Acetyltransf_3 NFINBLID_01787 1046629.Ssal_01778 1.55e-61 189.0 COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,4HIMN@91061|Bacilli 91061|Bacilli J Belongs to the bacterial ribosomal protein bL27 family rpmA GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - ko:K02899 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L27 NFINBLID_01788 264199.stu0417 1.99e-64 198.0 COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,4HIGK@91061|Bacilli 91061|Bacilli J This protein binds to 23S rRNA in the presence of protein L20 rplU GO:0003674,GO:0003735,GO:0005198 - ko:K02888 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L21p NFINBLID_01789 1046629.Ssal_01780 4.4e-107 310.0 COG0454@1|root,COG0456@2|Bacteria 2|Bacteria K acetyltransferase - - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_7 NFINBLID_01790 904306.HMPREF9192_0325 0.0 883.0 COG0438@1|root,COG0438@2|Bacteria,1TQZR@1239|Firmicutes 1239|Firmicutes M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 gtf2 - - - - - - - - - - - - NFINBLID_01791 1046629.Ssal_01782 0.0 986.0 COG0438@1|root,COG0438@2|Bacteria,1TR6K@1239|Firmicutes,4HGDG@91061|Bacilli 91061|Bacilli M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon gtf1 - - - - - - - - - - - Glycos_transf_1 NFINBLID_01792 904306.HMPREF9192_0323 5.31e-284 777.0 COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,4HAV9@91061|Bacilli 91061|Bacilli H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS thiI - 2.8.1.4 ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07461 - ko00000,ko00001,ko01000,ko03016 - - - THUMP,ThiI NFINBLID_01793 1046629.Ssal_01786 1.93e-266 730.0 COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,4HAEE@91061|Bacilli 91061|Bacilli E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes iscS2 - 2.8.1.7 ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 - R07460,R11528,R11529 RC01789,RC02313 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 - - - Aminotran_5 NFINBLID_01794 1005705.HMPREF9967_0802 3.68e-08 57.0 2DIXV@1|root,304C8@2|Bacteria,1TWH5@1239|Firmicutes,4I5AH@91061|Bacilli,43G9W@68892|Streptococcus infantis 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01795 1046629.Ssal_01788 1.37e-286 784.0 COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,4HBJM@91061|Bacilli 91061|Bacilli H Belongs to the folylpolyglutamate synthase family folC - 6.3.2.12,6.3.2.17 ko:K11754 ko00790,ko01100,map00790,map01100 M00126,M00841 R00942,R02237,R04241 RC00064,RC00090,RC00162 ko00000,ko00001,ko00002,ko01000 - - iSB619.SA_RS08370 Mur_ligase_C,Mur_ligase_M NFINBLID_01796 435842.HMPREF0848_00027 0.0 887.0 COG1249@1|root,COG1249@2|Bacteria,1TQFH@1239|Firmicutes,4HCT8@91061|Bacilli 91061|Bacilli C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family gor GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.7 ko:K00383 ko00480,ko04918,map00480,map04918 - R00094,R00115 RC00011 ko00000,ko00001,ko01000 - - - Pyr_redox_2,Pyr_redox_dim NFINBLID_01797 1046629.Ssal_01791 0.0 1198.0 COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,4H9KR@91061|Bacilli 91061|Bacilli G phosphotransferase system fruA - 2.7.1.202 ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 M00273 R03232 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.2.1 - - PTS_EIIA_2,PTS_EIIC,PTS_IIB NFINBLID_01798 1046629.Ssal_01792 2.63e-211 584.0 COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,4HANU@91061|Bacilli 91061|Bacilli H Belongs to the carbohydrate kinase PfkB family. LacC subfamily pfkB GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.56 ko:K00882 ko00051,map00051 - R02071 RC00002,RC00017 ko00000,ko00001,ko01000 - - iYO844.BSU14390 PfkB NFINBLID_01799 1046629.Ssal_01793 1.53e-162 456.0 COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,4HDT9@91061|Bacilli 91061|Bacilli K transcriptional fruR - - ko:K03436 - - - - ko00000,ko03000 - - - DeoRC,HTH_DeoR NFINBLID_01800 904306.HMPREF9192_0315 2.22e-290 804.0 COG1418@1|root,COG4372@1|root,COG1418@2|Bacteria,COG4372@2|Bacteria,1TP48@1239|Firmicutes,4HC9J@91061|Bacilli 91061|Bacilli D Endoribonuclease that initiates mRNA decay rny GO:0003674,GO:0005488,GO:0005515,GO:0042802 - ko:K18682 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - DUF3552,HD,KH_1 NFINBLID_01801 1046629.Ssal_01795 6.58e-116 331.0 COG1854@1|root,COG1854@2|Bacteria,1V1V3@1239|Firmicutes,4HFR0@91061|Bacilli 91061|Bacilli H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) luxS - 4.4.1.21 ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 M00609 R01291 RC00069,RC01929 ko00000,ko00001,ko00002,ko01000 - - - LuxS NFINBLID_01802 1046629.Ssal_01796 4.63e-177 494.0 COG0825@1|root,COG0825@2|Bacteria,1UHNS@1239|Firmicutes,4HA4C@91061|Bacilli 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA accA - 2.1.3.15,6.4.1.2 ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - ACCA NFINBLID_01803 1046629.Ssal_01797 1.99e-203 563.0 COG0777@1|root,COG0777@2|Bacteria,1TP4U@1239|Firmicutes,4HAI7@91061|Bacilli 91061|Bacilli I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA accD - 2.1.3.15,6.4.1.2 ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04386 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Carboxyl_trans NFINBLID_01804 1046629.Ssal_01798 0.0 886.0 COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,4HARK@91061|Bacilli 91061|Bacilli I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism accC - 6.3.4.14,6.4.1.2 ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742,R04385 RC00040,RC00253,RC00367 ko00000,ko00001,ko00002,ko01000 - - - Biotin_carb_C,Biotin_carb_N,CPSase_L_D2 NFINBLID_01805 1046629.Ssal_01800 1.19e-93 273.0 COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,4HGX1@91061|Bacilli 91061|Bacilli I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs fabZ - 4.2.1.59 ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121 RC00831,RC01095 ko00000,ko00001,ko00002,ko01000,ko01004 - - - FabA NFINBLID_01806 322159.STER_0435 1.75e-87 259.0 COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,4HKCS@91061|Bacilli 91061|Bacilli I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA accB - - ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 M00082,M00376 R00742 RC00040,RC00367 ko00000,ko00001,ko00002 - - - Biotin_lipoyl NFINBLID_01807 1046629.Ssal_01802 3.69e-297 810.0 COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP fabF - 2.3.1.179 ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 M00083,M00572 R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119 RC00039,RC02728,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - Ketoacyl-synt_C,ketoacyl-synt NFINBLID_01808 904306.HMPREF9192_0291 2.76e-163 458.0 COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,4HAA6@91061|Bacilli 91061|Bacilli IQ reductase fabG GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 M00083,M00572 R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671 RC00029,RC00117 ko00000,ko00001,ko00002,ko01000,ko01004 - - iYO844.BSU15910 adh_short_C2 NFINBLID_01809 1046629.Ssal_01804 8.74e-207 573.0 COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,4HBCU@91061|Bacilli 91061|Bacilli I Malonyl CoA-acyl carrier protein transacylase fabD - 2.3.1.39 ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 M00082 R01626,R11671 RC00004,RC00039,RC02727 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 - - - Acyl_transf_1 NFINBLID_01810 1046629.Ssal_01805 2.65e-220 608.0 COG2070@1|root,COG2070@2|Bacteria,1TPC3@1239|Firmicutes,4H9T0@91061|Bacilli 91061|Bacilli S 2-Nitropropane dioxygenase fabK - 1.3.1.9 ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00083 R04429,R04724,R04955,R04958,R04961,R04966,R04969,R07765 RC00052,RC00076 ko00000,ko00001,ko00002,ko01000,ko01004 - - - NMO NFINBLID_01811 1046629.Ssal_01806 2.12e-40 134.0 COG0236@1|root,COG0236@2|Bacteria,1VGIY@1239|Firmicutes,4HP0V@91061|Bacilli 91061|Bacilli IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis acpP GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - ko:K02078 - - - - ko00000,ko00001 - - - PP-binding NFINBLID_01812 1046629.Ssal_01807 7.34e-222 612.0 COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,4HATK@91061|Bacilli 91061|Bacilli I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids fabH - 2.3.1.180 ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 M00082,M00083 R10707 RC00004,RC02729,RC02888 ko00000,ko00001,ko00002,ko01000,ko01004 - - - ACP_syn_III,ACP_syn_III_C NFINBLID_01813 1046629.Ssal_01808 2.67e-96 280.0 COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,4HIMR@91061|Bacilli 91061|Bacilli K Transcriptional regulator, MarR family XK27_02735 - - - - - - - - - - - MarR NFINBLID_01814 1046629.Ssal_01809 9.63e-181 504.0 COG1024@1|root,COG1024@2|Bacteria,1TQ2V@1239|Firmicutes,4HBT0@91061|Bacilli 91061|Bacilli I Belongs to the enoyl-CoA hydratase isomerase family phaB GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576 5.3.3.14,5.3.3.18 ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 - R07639,R09837,R09839 RC00004,RC00326,RC01078,RC02689,RC03003 ko00000,ko00001,ko01000,ko01004 - - - ECH_1 NFINBLID_01815 1046629.Ssal_01810 7.51e-152 426.0 COG0637@1|root,COG0637@2|Bacteria,1VA1U@1239|Firmicutes,4HMKX@91061|Bacilli 91061|Bacilli S HAD hydrolase, family IA, variant 3 yhfA - - - - - - - - - - - HAD_2 NFINBLID_01816 1046629.Ssal_01811 0.0 892.0 COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,4HAEP@91061|Bacilli 91061|Bacilli E Belongs to the aspartokinase family lysC GO:0000166,GO:0003674,GO:0003824,GO:0004072,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017076,GO:0019202,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 M00016,M00017,M00018,M00033,M00525,M00526,M00527 R00480 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU03790 AA_kinase,ACT,ACT_7 NFINBLID_01817 1046629.Ssal_01812 5.34e-245 672.0 COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,4HAEC@91061|Bacilli 91061|Bacilli E aspartate--ammonia ligase asnA GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.1.1 ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 - R00483 RC00010 ko00000,ko00001,ko01000 - - - AsnA NFINBLID_01818 1046629.Ssal_01813 9.53e-317 863.0 COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,4HA6M@91061|Bacilli 91061|Bacilli J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family rumA_1 - 2.1.1.190,2.1.1.35 ko:K00557,ko:K03215 - - - - ko00000,ko01000,ko03009,ko03016 - - - TRAM,tRNA_U5-meth_tr NFINBLID_01819 1046629.Ssal_01814 6.04e-174 486.0 COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,4HKE3@91061|Bacilli 91061|Bacilli S Regulatory protein RecX recX - - ko:K03565 - - - - ko00000,ko03400 - - - RecX NFINBLID_01820 1046629.Ssal_01815 1.99e-132 374.0 COG3557@1|root,COG3557@2|Bacteria,1TRX8@1239|Firmicutes,4H9NM@91061|Bacilli 91061|Bacilli J Belongs to the UPF0374 family ygaC - - ko:K07586 - - - - ko00000 - - - DUF402 NFINBLID_01821 1046629.Ssal_01816 3.78e-133 379.0 2F8BM@1|root,340QP@2|Bacteria,1W4V4@1239|Firmicutes,4HR72@91061|Bacilli 91061|Bacilli S Domain of unknown function (DUF1803) - - - - - - - - - - - - DUF1803 NFINBLID_01822 1046629.Ssal_01817 3.56e-208 577.0 COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,4H9T8@91061|Bacilli 91061|Bacilli C inorganic pyrophosphatase ppaC GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237,GO:0044424,GO:0044464 3.6.1.1 ko:K15986 ko00190,map00190 - - - ko00000,ko00001,ko01000 - - - DHH,DHHA2 NFINBLID_01831 1046629.Ssal_00210 8.62e-66 201.0 COG0526@1|root,COG0526@2|Bacteria 2|Bacteria CO cell redox homeostasis bta - 1.8.1.8 ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko01000,ko03110 - - - Thioredoxin,TraF NFINBLID_01832 435842.HMPREF0848_01462 5.23e-77 231.0 COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,4HIVC@91061|Bacilli 91061|Bacilli L thioesterase yneP - - ko:K07107 - - - - ko00000,ko01000 - - - 4HBT,4HBT_2 NFINBLID_01833 1046629.Ssal_00214 2.05e-182 508.0 COG2110@1|root,COG2110@2|Bacteria,1TQSZ@1239|Firmicutes,4HCXD@91061|Bacilli 91061|Bacilli S Macro domain protein - - - - - - - - - - - - Macro NFINBLID_01834 904306.HMPREF9192_0562 1.27e-66 202.0 COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,4HKKX@91061|Bacilli 91061|Bacilli O Belongs to the thioredoxin family trxA - - ko:K03671 ko04621,ko05418,map04621,map05418 - - - ko00000,ko00001,ko03110 - - - Thioredoxin NFINBLID_01835 1046629.Ssal_00216 7.98e-93 271.0 COG1832@1|root,COG1832@2|Bacteria,1V7C7@1239|Firmicutes,4HIZT@91061|Bacilli 91061|Bacilli S CoA-binding protein yneT - - ko:K06929 - - - - ko00000 - - - CoA_binding_2 NFINBLID_01836 1046629.Ssal_00217 3.58e-180 502.0 COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,4HA74@91061|Bacilli 91061|Bacilli L Hydrolase, tatd tatD GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - ko:K03424 - - - - ko00000,ko01000 - - - TatD_DNase NFINBLID_01837 1046629.Ssal_00218 2.57e-128 365.0 COG1658@1|root,COG1658@2|Bacteria,1V3K3@1239|Firmicutes,4HH5Y@91061|Bacilli 91061|Bacilli J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step rnmV GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043822,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.8 ko:K05985 - - - - ko00000,ko01000 - - - DUF4093,Toprim,Toprim_4 NFINBLID_01838 1046629.Ssal_00219 1.76e-198 551.0 COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,4HA4R@91061|Bacilli 91061|Bacilli J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits ksgA GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 ko:K02528 - - R10716 RC00003,RC03257 ko00000,ko01000,ko03009 - - - RrnaAD NFINBLID_01840 904306.HMPREF9192_0568 1.25e-207 574.0 COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,4HA9W@91061|Bacilli 91061|Bacilli G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit rsgA - 3.1.3.100 ko:K06949 ko00730,ko01100,map00730,map01100 - R00615,R02135 RC00002,RC00017 ko00000,ko00001,ko01000,ko03009 - - - RsgA_GTPase,RsgA_N NFINBLID_01841 904306.HMPREF9192_0569 6.64e-154 432.0 COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H9RW@91061|Bacilli 91061|Bacilli G Belongs to the ribulose-phosphate 3-epimerase family rpe GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00004,M00007 R01529 RC00540 ko00000,ko00001,ko00002,ko01000 - - - Ribul_P_3_epim NFINBLID_01842 1046629.Ssal_00222 5.29e-151 424.0 COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,4HHS1@91061|Bacilli 91061|Bacilli H thiamine pyrophosphokinase thiN - 2.7.6.2 ko:K00949 ko00730,ko01100,map00730,map01100 - R00619 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TPK_B1_binding,TPK_catalytic NFINBLID_01843 1046629.Ssal_00223 5.68e-230 642.0 COG1322@1|root,COG1322@2|Bacteria,1TPWI@1239|Firmicutes,4HE2N@91061|Bacilli 91061|Bacilli S RmuC domain protein rmuC - - ko:K09760 - - - - ko00000 - - - RmuC NFINBLID_01844 1046629.Ssal_00224 4.14e-229 630.0 COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,4HB1M@91061|Bacilli 91061|Bacilli S 3'-5' exoribonuclease yhaM yhaM GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - ko:K03698 - - - - ko00000,ko01000,ko03019 - - - HD,tRNA_anti-codon NFINBLID_01845 904306.HMPREF9192_0573 7.91e-184 512.0 COG0503@1|root,COG0503@2|Bacteria,1TPN9@1239|Firmicutes,4HB8I@91061|Bacilli 91061|Bacilli F operon repressor purR - - ko:K09685 - - - - ko00000,ko03000 - - - Pribosyltran,PuR_N NFINBLID_01846 1046629.Ssal_00226 4.89e-91 266.0 COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,4HFMZ@91061|Bacilli 91061|Bacilli J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit rpsL GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02950 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosom_S12_S23 NFINBLID_01847 1046629.Ssal_00227 4.66e-105 303.0 COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,4H9PA@91061|Bacilli 91061|Bacilli J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA rpsG GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02992 ko03010,map03010 M00178,M00179 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S7 NFINBLID_01848 1046629.Ssal_00229 0.0 1358.0 COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,4HAB8@91061|Bacilli 91061|Bacilli J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome fusA - - ko:K02355 - - - - ko00000,ko03012,ko03029 - - - EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2 NFINBLID_01849 1005704.HMPREF9968_0695 1.07e-238 656.0 COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,4H9NS@91061|Bacilli,1WPP9@1303|Streptococcus oralis 91061|Bacilli C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family gap GO:0000166,GO:0002020,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0019362,GO:0019637,GO:0019674,GO:0019899,GO:0034641,GO:0036094,GO:0043891,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.2.1.12 ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01061 RC00149 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 - - - Gp_dh_C,Gp_dh_N NFINBLID_01850 1046629.Ssal_00231 2.98e-153 432.0 28KD0@1|root,2Z9ZS@2|Bacteria,1V2YR@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - NFINBLID_01851 1046629.Ssal_00232 1.35e-282 773.0 COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,4H9R3@91061|Bacilli 91061|Bacilli F Belongs to the phosphoglycerate kinase family pgk GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 M00001,M00002,M00003,M00165,M00166,M00308,M00552 R01512 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000,ko04147 - - iSB619.SA_RS04145 PGK NFINBLID_01852 1046629.Ssal_00233 4.38e-113 325.0 COG4129@1|root,COG4129@2|Bacteria,1VAJG@1239|Firmicutes,4HKDZ@91061|Bacilli 91061|Bacilli S Fusaric acid resistance protein-like - - - - - - - - - - - - ArAE_1,FUSC_2 NFINBLID_01853 1046629.Ssal_00234 4e-82 243.0 COG0789@1|root,COG0789@2|Bacteria,1V6JE@1239|Firmicutes,4HKM6@91061|Bacilli 91061|Bacilli K Transcriptional regulator glnR GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016053,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903506,GO:2000112,GO:2001141 - ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 M00439 - - ko00000,ko00001,ko00002,ko02000,ko03000 3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25 - - MerR_1 NFINBLID_01854 1046629.Ssal_00235 0.0 907.0 COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,4HACE@91061|Bacilli 91061|Bacilli E glutamine synthetase glnA - 6.3.1.2 ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 - R00253 RC00010,RC02798 ko00000,ko00001,ko01000,ko04147 - - - Gln-synt_C,Gln-synt_N NFINBLID_01855 435842.HMPREF0848_01440 4.18e-148 417.0 COG3942@1|root,COG3942@2|Bacteria,1V8WM@1239|Firmicutes,4HIMT@91061|Bacilli 91061|Bacilli M CHAP domain protein sle1 - 3.5.1.28 ko:K22409 - - - - ko00000,ko01000 - CBM50 - CHAP,LysM NFINBLID_01856 1302863.I872_06440 0.0 1036.0 COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,4HCQ7@91061|Bacilli 91061|Bacilli L Recombinase - - - - - - - - - - - - DUF4368,Recombinase,Resolvase,Zn_ribbon_recom NFINBLID_01858 563038.HMPREF0851_02088 9.25e-178 496.0 2DM9G@1|root,328GS@2|Bacteria,1VWN6@1239|Firmicutes 1239|Firmicutes S Replication-relaxation - - - - - - - - - - - - Replic_Relax NFINBLID_01859 563038.HMPREF0851_02089 0.0 1366.0 COG0433@1|root,COG0433@2|Bacteria 2|Bacteria S helicase activity - - - - - - - - - - - - DUF853,DUF87,TraG-D_C,TrwB_AAD_bind NFINBLID_01862 1214184.ALKY01000022_gene689 1.7e-27 102.0 2B43I@1|root,31WU1@2|Bacteria,1U9AC@1239|Firmicutes,4IJD0@91061|Bacilli,1WU42@1307|Streptococcus suis 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01863 1214184.ALKY01000022_gene690 3.11e-181 513.0 29R49@1|root,30C5I@2|Bacteria,1U98A@1239|Firmicutes,4IJAW@91061|Bacilli,1WU1J@1307|Streptococcus suis 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01864 1201292.DR75_2020 2.51e-236 659.0 COG0270@1|root,COG0270@2|Bacteria,1TPNE@1239|Firmicutes,4HB9C@91061|Bacilli,4B0NU@81852|Enterococcaceae 91061|Bacilli L C-5 cytosine-specific DNA methylase hpaIIM - 2.1.1.37 ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 M00035 R04858 RC00003,RC00332 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 - - - DNA_methylase NFINBLID_01865 1201292.DR75_2019 1.24e-132 384.0 28K88@1|root,2Z9W2@2|Bacteria,1VRIE@1239|Firmicutes,4HYND@91061|Bacilli,4B4Z0@81852|Enterococcaceae 91061|Bacilli L NgoPII restriction endonuclease - - - - - - - - - - - - RE_NgoPII NFINBLID_01866 862967.SIR_0278 2.75e-190 541.0 29U29@1|root,30FBH@2|Bacteria,1TVSD@1239|Firmicutes,4I41I@91061|Bacilli,42DU7@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01870 435842.HMPREF0848_01439 0.0 1108.0 COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,4HAAP@91061|Bacilli 91061|Bacilli S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay rnjA GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - ko:K12574 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03019 - - - Lactamase_B,RMMBL NFINBLID_01871 1046629.Ssal_00239 4.54e-45 145.0 COG5503@1|root,COG5503@2|Bacteria,1VEI7@1239|Firmicutes,4HNSK@91061|Bacilli 91061|Bacilli S Belongs to the UPF0356 family ykzG - - - - - - - - - - - DUF1447 NFINBLID_01872 1046629.Ssal_00240 4.43e-152 428.0 COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,4HHD7@91061|Bacilli 91061|Bacilli O COG1214, inactive homolog of metal-dependent proteases yeaZ GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409,ko:K14742 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 NFINBLID_01873 435842.HMPREF0848_01436 3.54e-94 275.0 COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,4HP50@91061|Bacilli 91061|Bacilli K This enzyme acetylates the N-terminal alanine of ribosomal protein S18 rimI - 2.3.1.128 ko:K03789 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_1,Acetyltransf_10,Acetyltransf_7 NFINBLID_01874 1046629.Ssal_00242 2.72e-237 653.0 COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,4HANB@91061|Bacilli 91061|Bacilli O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction tsaD GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 ko:K01409 - - R10648 RC00070,RC00416 ko00000,ko01000,ko03016 - - - Peptidase_M22 NFINBLID_01875 435842.HMPREF0848_01434 2.7e-143 406.0 COG1296@1|root,COG1296@2|Bacteria,1V64T@1239|Firmicutes,4HH44@91061|Bacilli 91061|Bacilli E AzlC protein XK27_12120 - - - - - - - - - - - AzlC NFINBLID_01876 435842.HMPREF0848_01433 4.65e-62 191.0 COG4392@1|root,COG4392@2|Bacteria,1VH9Q@1239|Firmicutes,4HRBI@91061|Bacilli 91061|Bacilli S branched-chain amino acid - - - - - - - - - - - - AzlD NFINBLID_01877 1046629.Ssal_00246 0.0 1587.0 COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,4HATQ@91061|Bacilli 91061|Bacilli L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity recD2 - 3.1.11.5 ko:K03581 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - AAA_30,HHH_4,HHH_5,UvrD_C_2 NFINBLID_01878 904306.HMPREF9192_0591 5.32e-135 384.0 COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,4HMGQ@91061|Bacilli 91061|Bacilli U Belongs to the peptidase S26 family lepB - 3.4.21.89 ko:K03100 ko02024,ko03060,map02024,map03060 - - - ko00000,ko00001,ko01000,ko01002 - - - Peptidase_S24,Peptidase_S26 NFINBLID_01879 322159.STER_1740 2.67e-196 546.0 COG1039@1|root,COG1039@2|Bacteria,1TQBE@1239|Firmicutes,4H9QR@91061|Bacilli 91061|Bacilli L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids rnhC GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 ko:K03471 ko03030,map03030 - - - ko00000,ko00001,ko01000,ko03032 - - - DUF3378,RNase_HII NFINBLID_01880 1302863.I872_01550 7.01e-36 124.0 COG3027@1|root,COG3027@2|Bacteria,1VFZS@1239|Firmicutes,4HP4T@91061|Bacilli 91061|Bacilli D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division - - - ko:K09888 - - - - ko00000,ko03036 - - - ZapA NFINBLID_01881 322159.STER_1738 6.31e-117 335.0 COG1286@1|root,COG1286@2|Bacteria 2|Bacteria S toxin biosynthetic process cvpA GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - ko:K03558 - - - - ko00000 - - - Colicin_V,Trypsin_2 NFINBLID_01882 435842.HMPREF0848_01427 0.0 1477.0 COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,4H9NZ@91061|Bacilli 91061|Bacilli L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity mutS2 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - ko:K07456 ko03430,map03430 - - - ko00000,ko00001,ko03400 - - - MutS_V,Smr NFINBLID_01883 904306.HMPREF9192_0604 0.0 1688.0 COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,4H9S7@91061|Bacilli 91061|Bacilli L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity polA GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 - R00375,R00376,R00377,R00378 RC02795 ko00000,ko00001,ko01000,ko03032,ko03400 - - - 5_3_exonuc,5_3_exonuc_N,DNA_pol_A NFINBLID_01885 585202.SMSK321_0738 8.67e-32 130.0 2DKAS@1|root,30920@2|Bacteria,1U4B0@1239|Firmicutes,4IE2N@91061|Bacilli,2TP5R@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01888 1046629.Ssal_00266 9.75e-277 756.0 COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,4H9UM@91061|Bacilli 91061|Bacilli L A G-specific adenine glycosylase mutY - - ko:K03575 ko03410,map03410 - - - ko00000,ko00001,ko01000,ko03400 - - - EndIII_4Fe-2S,HhH-GPD,NUDIX_4 NFINBLID_01889 1214166.ALLG01000021_gene137 2.26e-52 181.0 2BJFN@1|root,32DS8@2|Bacteria,1U8WY@1239|Firmicutes,4IIVI@91061|Bacilli,1WSBS@1307|Streptococcus suis 91061|Bacilli - - XK27_05745 - - - - - - - - - - - - NFINBLID_01890 904306.HMPREF9192_0608 1.88e-62 191.0 COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,4HKHD@91061|Bacilli 91061|Bacilli J Binds together with S18 to 16S ribosomal RNA rpsF GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - ko:K02990 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011,ko03029 - - - Ribosomal_S6 NFINBLID_01891 904306.HMPREF9192_0609 4.18e-118 338.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB NFINBLID_01892 1046629.Ssal_00271 4.1e-47 151.0 COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,4HKCC@91061|Bacilli 91061|Bacilli J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit rpsR GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - ko:K02963 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S18 NFINBLID_01894 1046629.Ssal_00273 2.31e-156 439.0 COG4858@1|root,COG4858@2|Bacteria,1VF5N@1239|Firmicutes,4HMVT@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF1129) XK27_01040 - - - - - - - - - - - DUF1129 NFINBLID_01895 435842.HMPREF0848_01411 5.76e-216 597.0 COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,4HE7S@91061|Bacilli 91061|Bacilli P COG0598 Mg2 and Co2 transporters corA - - ko:K03284 - - - - ko00000,ko02000 1.A.35.1,1.A.35.3 - - CorA NFINBLID_01896 435842.HMPREF0848_01410 0.0 1856.0 COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,4HAW9@91061|Bacilli 91061|Bacilli L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate uvrA - - ko:K03701 ko03420,map03420 - - - ko00000,ko00001,ko03400 - - - ABC_tran NFINBLID_01900 1123298.KB904096_gene254 4.51e-38 144.0 2DWQH@1|root,341F6@2|Bacteria,1W6SH@1239|Firmicutes,4HX74@91061|Bacilli 91061|Bacilli - - blpT - - - - - - - - - - - Thioredoxin NFINBLID_01902 1046629.Ssal_00280 4.83e-255 699.0 COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,4HAT7@91061|Bacilli 91061|Bacilli E Belongs to the peptidase M24B family pepP - 3.4.11.9,3.4.13.9 ko:K01262,ko:K01271 - - - - ko00000,ko01000,ko01002 - - - Creatinase_N,Peptidase_M24 NFINBLID_01903 1046629.Ssal_00281 3.59e-111 318.0 COG2131@1|root,COG2131@2|Bacteria,1V8V0@1239|Firmicutes,4IQZA@91061|Bacilli 91061|Bacilli F ComE operon protein 2 comEB - 3.5.4.12 ko:K01493 ko00240,ko01100,map00240,map01100 M00429 R01663 RC00074 ko00000,ko00001,ko00002,ko01000,ko02044 - - - dCMP_cyt_deam_1 NFINBLID_01904 904306.HMPREF9192_0624 8.59e-127 361.0 COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,4H9YX@91061|Bacilli 91061|Bacilli J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase efp GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - ko:K02356 - - - - ko00000,ko03012 - - - EFP,EFP_N,Elong-fact-P_C NFINBLID_01905 1046629.Ssal_00283 7.41e-80 238.0 COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,4HJ7T@91061|Bacilli 91061|Bacilli S protein conserved in bacteria WQ51_04310 - - ko:K10947 - - - - ko00000,ko03000 - - - Asp23 NFINBLID_01906 1046629.Ssal_00284 6.3e-95 277.0 COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,4HKMU@91061|Bacilli 91061|Bacilli K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons nusB - - ko:K03625 - - - - ko00000,ko03009,ko03021 - - - NusB NFINBLID_01907 435842.HMPREF0848_01398 2.12e-226 624.0 COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes 1239|Firmicutes K Transcriptional regulator scrR - - ko:K03484 - - - - ko00000,ko03000 - - - LacI,Peripla_BP_1,Peripla_BP_3 NFINBLID_01908 1046629.Ssal_00286 0.0 1001.0 COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,4H9Y7@91061|Bacilli 91061|Bacilli G invertase scrB - 3.2.1.26 ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 - R00801,R00802,R02410,R03635,R03921,R06088 RC00028,RC00077 ko00000,ko00001,ko01000 - GH32 - Glyco_hydro_32C,Glyco_hydro_32N NFINBLID_01909 1046629.Ssal_00287 0.0 1204.0 COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,4HA0I@91061|Bacilli 91061|Bacilli G pts system scrA - 2.7.1.211 ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 M00269 R00811 RC00017,RC03206 ko00000,ko00001,ko00002,ko01000,ko02000 4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9 - - PTS_EIIA_1,PTS_EIIB,PTS_EIIC NFINBLID_01910 904306.HMPREF9192_0630 1.95e-219 604.0 COG1940@1|root,COG1940@2|Bacteria,1TQU4@1239|Firmicutes,4HA1C@91061|Bacilli 91061|Bacilli GK Fructokinase scrK - 2.7.1.4 ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 - R00760,R00867,R03920 RC00002,RC00017 ko00000,ko00001,ko01000 - - - ROK NFINBLID_01911 1046629.Ssal_00290 8.8e-241 660.0 COG1482@1|root,COG1482@2|Bacteria,1VRGI@1239|Firmicutes,4HBFW@91061|Bacilli 91061|Bacilli G mannose-6-phosphate isomerase manA - 5.3.1.8 ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 M00114 R01819 RC00376 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU12020 PMI_typeI NFINBLID_01913 1046629.Ssal_00292 0.0 1652.0 COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,4HA22@91061|Bacilli 91061|Bacilli U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane secA GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 M00335 - - ko00000,ko00001,ko00002,ko02044 3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4 - - SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW NFINBLID_01914 904306.HMPREF9192_0634 9.67e-250 685.0 COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes 1239|Firmicutes E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroH - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS07240 DAHP_synth_1 NFINBLID_01915 1046629.Ssal_00295 1.28e-247 680.0 COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes 1239|Firmicutes E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) aroG - 2.5.1.54 ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 M00022 R01826 RC00435 ko00000,ko00001,ko00002,ko01000 - - iHN637.CLJU_RS07240 DAHP_synth_1 NFINBLID_01916 1046629.Ssal_00296 4.16e-78 232.0 COG0736@1|root,COG0736@2|Bacteria,1VA0T@1239|Firmicutes,4HKBI@91061|Bacilli 91061|Bacilli I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein acpS - 2.7.8.7 ko:K00997 ko00770,map00770 - R01625 RC00002 ko00000,ko00001,ko01000 - - iYO844.BSU04620 ACPS NFINBLID_01917 1046629.Ssal_00297 1.84e-241 666.0 COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,4HA95@91061|Bacilli 91061|Bacilli E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids alr - 5.1.1.1,5.1.1.5 ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 - R00401 RC00285 ko00000,ko00001,ko01000,ko01011 - - - Ala_racemase_C,Ala_racemase_N NFINBLID_01918 435842.HMPREF0848_01388 0.0 1303.0 COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,4HAWN@91061|Bacilli 91061|Bacilli L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) recG - 3.6.4.12 ko:K03655 ko03440,map03440 - - - ko00000,ko00001,ko01000,ko03400 - - - DEAD,Helicase_C,RecG_wedge NFINBLID_01922 1046629.Ssal_00306 4.07e-43 140.0 COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes 1239|Firmicutes K Transcriptional regulator yozG - - ko:K07727 - - - - ko00000,ko03000 - - - HTH_26 NFINBLID_01924 1046629.Ssal_00308 1.67e-227 627.0 COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,4H9YJ@91061|Bacilli 91061|Bacilli EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D ansB - 3.5.1.1 ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 - R00485 RC00010,RC02798 ko00000,ko00001,ko01000 - - - Asparaginase NFINBLID_01925 435842.HMPREF0848_01382 0.0 887.0 COG0561@1|root,COG4696@1|root,COG0561@2|Bacteria,COG4696@2|Bacteria,1TSZZ@1239|Firmicutes,4HB54@91061|Bacilli 91061|Bacilli S hydrolases of the HAD superfamily - - - - - - - - - - - - Hydrolase_3,PRA-PH NFINBLID_01926 1046629.Ssal_00310 8.7e-172 493.0 COG3064@1|root,COG3064@2|Bacteria,1VK5M@1239|Firmicutes,4HS44@91061|Bacilli 91061|Bacilli M Membrane yebC - - - - - - - - - - - zf-ribbon_3,zinc_ribbon_2 NFINBLID_01927 1046629.Ssal_00311 0.0 1056.0 COG4640@1|root,COG4640@2|Bacteria 2|Bacteria KT response to antibiotic - - - - - - - - - - - - - NFINBLID_01928 1046629.Ssal_00312 3.85e-98 286.0 COG3279@1|root,COG3279@2|Bacteria,1VBF7@1239|Firmicutes,4HHGZ@91061|Bacilli 91061|Bacilli K LytTr DNA-binding domain protein XK27_02470 - - - - - - - - - - - LytTR NFINBLID_01929 322159.STER_1683 3.31e-144 409.0 COG4758@1|root,COG4758@2|Bacteria,1VGSF@1239|Firmicutes,4IRBC@91061|Bacilli 91061|Bacilli S membrane - - - - - - - - - - - - - NFINBLID_01930 1046629.Ssal_00314 0.0 1026.0 COG0443@1|root,COG0443@2|Bacteria,1TSUC@1239|Firmicutes 1239|Firmicutes O MreB/Mbl protein - - - ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 - - - ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 1.A.33.1 - - HSP70 NFINBLID_01932 1046629.Ssal_00316 8.38e-187 519.0 COG1131@1|root,COG1131@2|Bacteria,1V0ED@1239|Firmicutes 1239|Firmicutes V Psort location CytoplasmicMembrane, score - - - ko:K21397 - - - - ko00000,ko02000 3.A.1 - - ABC2_membrane,ABC_tran,FHA NFINBLID_01935 365659.smi_1723 6.15e-14 83.2 2DKFM@1|root,309CC@2|Bacteria,1U4TK@1239|Firmicutes,4IEJ2@91061|Bacilli,2TQA8@28037|Streptococcus mitis 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01936 1046629.Ssal_00320 3.35e-288 790.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity dcuS GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016021,GO:0016043,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031323,GO:0031326,GO:0035556,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051259,GO:0051260,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 2.7.13.3 ko:K02476,ko:K07701,ko:K07706,ko:K11614 ko02020,ko02024,map02020,map02024 M00488,M00490,M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,PAS,SPOB_a,sCache_3_2 NFINBLID_01937 1046629.Ssal_00321 6.12e-297 814.0 COG3290@1|root,COG3290@2|Bacteria 2|Bacteria T protein histidine kinase activity - - 2.7.13.3 ko:K07706 ko02020,ko02024,map02020,map02024 M00495 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c_5,PAS_9 NFINBLID_01938 1046629.Ssal_00322 0.0 2097.0 COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,4HAY6@91061|Bacilli 91061|Bacilli L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination rexB GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.6.4.12 ko:K16899 - - - - ko00000,ko01000,ko03400 - - - Exonuc_V_gamma,PDDEXK_1,UvrD_C NFINBLID_01939 1046629.Ssal_00325 0.0 2312.0 COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,4HA64@91061|Bacilli 91061|Bacilli L ATP-dependent helicase nuclease subunit A addA GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 3.6.4.12 ko:K16898 - - - - ko00000,ko01000,ko03400 - - - PDDEXK_1,UvrD-helicase,UvrD_C NFINBLID_01940 435842.HMPREF0848_01364 2.99e-162 455.0 COG1811@1|root,COG1811@2|Bacteria,1TQWV@1239|Firmicutes,4HEYY@91061|Bacilli 91061|Bacilli S Protein of unknown function (DUF554) - - - ko:K07150 - - - - ko00000 - - - DUF554 NFINBLID_01941 1046629.Ssal_00328 3.53e-170 475.0 COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,4HCEU@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein ecsA_2 - - ko:K01990 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - ABC_tran NFINBLID_01942 1046629.Ssal_00329 0.0 983.0 28MBB@1|root,2ZAPV@2|Bacteria,1TSZA@1239|Firmicutes,4HDKH@91061|Bacilli 91061|Bacilli - - XK27_00765 - - ko:K01992 - M00254 - - ko00000,ko00002,ko02000 3.A.1 - - - NFINBLID_01943 904306.HMPREF9192_0659 1.43e-181 506.0 COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,4HA9B@91061|Bacilli 91061|Bacilli E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate proB GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 2.7.2.11 ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 M00015 R00239 RC00002,RC00043 ko00000,ko00001,ko00002,ko01000 - - - AA_kinase NFINBLID_01944 904306.HMPREF9192_0660 7.54e-284 777.0 COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,4HB7B@91061|Bacilli 91061|Bacilli E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate proA GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 M00015 R03313 RC00684 ko00000,ko00001,ko00002,ko01000 - - iYO844.BSU13130 Aldedh NFINBLID_01945 435842.HMPREF0848_01359 1.32e-78 234.0 COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes 1239|Firmicutes J Membrane - - - - - - - - - - - - DUF805,zinc_ribbon_2 NFINBLID_01946 435842.HMPREF0848_01358 1.7e-42 144.0 COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes,4HQ7Q@91061|Bacilli 91061|Bacilli J Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 NFINBLID_01947 435842.HMPREF0848_01358 1.37e-81 242.0 COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes,4HQ7Q@91061|Bacilli 91061|Bacilli J Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 NFINBLID_01948 1046629.Ssal_00333 4.06e-58 183.0 COG3152@1|root,COG3152@2|Bacteria,1V90R@1239|Firmicutes,4HQ7Q@91061|Bacilli 91061|Bacilli J Protein of unknown function (DUF805) - - - - - - - - - - - - DUF805 NFINBLID_01950 264199.stu1704 1.55e-92 281.0 2DDKD@1|root,2ZIF1@2|Bacteria,1W5UA@1239|Firmicutes,4HZND@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01952 322159.STER_1668 2.67e-222 613.0 COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,4H9U2@91061|Bacilli 91061|Bacilli J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA rsmH GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 ko:K03438 - - - - ko00000,ko01000,ko03009 - - - Methyltransf_5 NFINBLID_01953 435842.HMPREF0848_01354 5.32e-60 186.0 COG4839@1|root,COG4839@2|Bacteria,1VCE5@1239|Firmicutes,4HM4W@91061|Bacilli 91061|Bacilli D cell division protein FtsL ftsL - - - - - - - - - - - DivIC NFINBLID_01954 435842.HMPREF0848_01353 0.0 1417.0 COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,4H9VQ@91061|Bacilli 91061|Bacilli M penicillin-binding protein pbpX GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 - - - ko00000,ko00001,ko01000,ko01011 - - - PASTA,PBP_dimer,Transpeptidase NFINBLID_01955 1046629.Ssal_00341 1.15e-235 649.0 COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,4H9TP@91061|Bacilli 91061|Bacilli M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan mraY - 2.7.8.13 ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 - R05629,R05630 RC00002,RC02753 ko00000,ko00001,ko01000,ko01011 9.B.146 - - Glycos_transf_4,MraY_sig1 NFINBLID_01956 1046629.Ssal_00342 7.55e-302 825.0 COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,4HA98@91061|Bacilli 91061|Bacilli JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures cshB GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009295,GO:0009409,GO:0009628,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 ko:K05592,ko:K18692 ko03018,map03018 - - - ko00000,ko00001,ko01000,ko03009,ko03019 - - - DEAD,Helicase_C NFINBLID_01957 1046629.Ssal_00344 0.0 892.0 COG0737@1|root,COG0737@2|Bacteria,1TQCW@1239|Firmicutes,4HAUC@91061|Bacilli 91061|Bacilli F Belongs to the 5'-nucleotidase family yunD - 3.1.3.5 ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 - R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346 RC00017 ko00000,ko00001,ko01000 - - - 5_nucleotid_C,Metallophos NFINBLID_01958 435842.HMPREF0848_01344 7.33e-109 320.0 COG4470@1|root,COG4470@2|Bacteria,1VA85@1239|Firmicutes,4HKF7@91061|Bacilli 91061|Bacilli J protein conserved in bacteria yutD - - - - - - - - - - - DUF1027 NFINBLID_01959 1046629.Ssal_00347 7.84e-286 780.0 COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,4H9NU@91061|Bacilli 91061|Bacilli J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs rlmN GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 ko:K06941 - - - - ko00000,ko01000,ko03009 - - - Fer4_14,Radical_SAM NFINBLID_01960 1046629.Ssal_00348 3.55e-116 333.0 COG4767@1|root,COG4767@2|Bacteria,1VKIA@1239|Firmicutes,4HQZW@91061|Bacilli 91061|Bacilli V Glycopeptide antibiotics resistance protein XK27_09885 - - - - - - - - - - - VanZ NFINBLID_01963 1046629.Ssal_00350 0.0 1098.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein mdlA - - ko:K06148,ko:K18889 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1,3.A.1.106.13,3.A.1.106.5 - - ABC_membrane,ABC_tran NFINBLID_01964 435842.HMPREF0848_01339 0.0 1071.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HA3S@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein mdlB - - ko:K06147,ko:K18890 ko02010,map02010 M00707 - - ko00000,ko00001,ko00002,ko02000 3.A.1.106,3.A.1.106.13,3.A.1.106.5,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NFINBLID_01965 1116231.SMA_1921 6.95e-17 75.5 2DZ2R@1|root,34C7V@2|Bacteria,1W3RP@1239|Firmicutes,4HZZT@91061|Bacilli 91061|Bacilli S Bacteriocin class II with double-glycine leader peptide - - - - - - - - - - - - Bacteriocin_IIc NFINBLID_01971 1046629.Ssal_00364 0.0 1472.0 COG2936@1|root,COG2936@2|Bacteria,1TT78@1239|Firmicutes,4HBA0@91061|Bacilli 91061|Bacilli E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline pepX - 3.4.14.11 ko:K01281 - - - - ko00000,ko01000,ko01002 - - - PepX_C,PepX_N,Peptidase_S15 NFINBLID_01972 1046629.Ssal_00365 4.43e-191 532.0 COG0580@1|root,COG0580@2|Bacteria,1TP4T@1239|Firmicutes,4HE39@91061|Bacilli 91061|Bacilli U Belongs to the MIP aquaporin (TC 1.A.8) family gla - - ko:K02440 - - - - ko00000,ko02000 1.A.8.1,1.A.8.2 - - MIP NFINBLID_01973 1046629.Ssal_00366 1.32e-116 337.0 COG1266@1|root,COG1266@2|Bacteria 2|Bacteria V CAAX protease self-immunity - - - ko:K07052 - - - - ko00000 - - - Abi NFINBLID_01974 1046629.Ssal_00367 1.32e-179 500.0 COG0346@1|root,COG0346@2|Bacteria,1VMPM@1239|Firmicutes,4HSVM@91061|Bacilli 91061|Bacilli E CppA N-terminal cppA - - - - - - - - - - - CppA_C,CppA_N NFINBLID_01975 1046629.Ssal_00368 1.08e-218 604.0 COG1680@1|root,COG1680@2|Bacteria,1TNZX@1239|Firmicutes,4IPJT@91061|Bacilli 91061|Bacilli V COG1680 Beta-lactamase class C and other penicillin binding proteins - - - - - - - - - - - - Beta-lactamase NFINBLID_01977 1114965.Spaf_1573 4.47e-165 511.0 COG4932@1|root,COG4932@2|Bacteria 2|Bacteria M domain protein - - - - - - - - - - - - Cna_B,Collagen_bind,FctA,Gram_pos_anchor,YSIRK_signal NFINBLID_01978 596329.HMPREF0631_1001 1.2e-120 347.0 COG0500@1|root,COG2226@2|Bacteria,1TR4Y@1239|Firmicutes,24DHJ@186801|Clostridia,25U8C@186804|Peptostreptococcaceae 186801|Clostridia H Methyltransferase - - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 NFINBLID_01979 1314.HKU360_01262 2.75e-25 107.0 COG1396@1|root,COG2932@1|root,COG1396@2|Bacteria,COG2932@2|Bacteria,1VDKY@1239|Firmicutes,4IS6B@91061|Bacilli 91061|Bacilli K Peptidase S24-like - - - - - - - - - - - - HTH_3,Peptidase_S24 NFINBLID_01980 218495.SUB0004 5.91e-06 47.8 COG1396@1|root,COG1396@2|Bacteria,1VK84@1239|Firmicutes,4ISBS@91061|Bacilli 91061|Bacilli K Cro/C1-type HTH DNA-binding domain - - - - - - - - - - - - HTH_3 NFINBLID_01982 888816.HMPREF9389_0724 8.24e-46 170.0 29RP8@1|root,30CSJ@2|Bacteria,1UAAQ@1239|Firmicutes,4IKNH@91061|Bacilli,1WS1U@1305|Streptococcus sanguinis 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01986 1123300.AUIN01000009_gene258 3.05e-129 381.0 COG4974@1|root,COG4974@2|Bacteria,1URNQ@1239|Firmicutes,4HEPI@91061|Bacilli 91061|Bacilli D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division xerS - - ko:K04763 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase NFINBLID_01988 322159.STER_1338 1.88e-70 213.0 2E59Z@1|root,33028@2|Bacteria,1VFMU@1239|Firmicutes,4HQG9@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01989 264199.stu1385 0.0 920.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH NFINBLID_01990 264199.stu1386 8.73e-172 490.0 2CWIF@1|root,32SZQ@2|Bacteria,1VBXK@1239|Firmicutes,4HWJ5@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01992 435842.HMPREF0848_01571 6.58e-07 50.8 COG1985@1|root,COG3666@1|root,COG1985@2|Bacteria,COG3666@2|Bacteria,1UHQU@1239|Firmicutes,4IS6M@91061|Bacilli 91061|Bacilli L An automated process has identified a potential problem with this gene model - - - - - - - - - - - - DDE_Tnp_1,DUF772 NFINBLID_01994 706437.HMPREF0813_01505 3.69e-41 146.0 29H4I@1|root,30423@2|Bacteria,1TVVB@1239|Firmicutes,4I4DM@91061|Bacilli,42E7R@671232|Streptococcus anginosus group 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_01995 1069533.Sinf_1806 2.83e-154 488.0 COG3087@1|root,COG3087@2|Bacteria 2|Bacteria D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - - - - - - - - - - Antigen_C,GbpC,Gram_pos_anchor,SPOR NFINBLID_01996 1214217.ALNF01000060_gene2203 1.21e-17 90.1 COG3115@1|root,COG3115@2|Bacteria 2|Bacteria D cell septum assembly dnaX - 2.4.99.16,2.7.7.7 ko:K02343,ko:K02519,ko:K07114,ko:K16147 ko00230,ko00240,ko00500,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map00500,map01100,map03030,map03430,map03440 M00260 R00375,R00376,R00377,R00378,R09994 RC02795 ko00000,ko00001,ko00002,ko01000,ko02000,ko03012,ko03029,ko03032,ko03400 1.A.13.2.2,1.A.13.2.3 GH13 - DNA_pol3_delta2,DNA_pol3_gamma3,DNA_pol3_tau_5,DUF4157,FliO,Gram_pos_anchor NFINBLID_01999 1234409.C683_0851 3.05e-100 333.0 COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,4HAZV@91061|Bacilli,4B026@81852|Enterococcaceae 91061|Bacilli L DNA topoisomerase traI - 5.99.1.2 ko:K03169 - - - - ko00000,ko01000,ko03032 - - - Topoisom_bac,Toprim,Toprim_Crpt,zf-C4_Topoisom NFINBLID_02002 1316408.HSISM1_1338 0.0 1492.0 COG1002@1|root,COG1002@2|Bacteria,1TRZH@1239|Firmicutes,4HE9W@91061|Bacilli 91061|Bacilli V Type II restriction enzyme, methylase subunits yeeA - - - - - - - - - - - N6_Mtase NFINBLID_02003 1198676.SMUGS5_05150 3.48e-40 146.0 2DN8K@1|root,32W3T@2|Bacteria 2|Bacteria - - - - - - - - - - - - - - - NFINBLID_02005 1005705.HMPREF9967_1059 8.51e-27 119.0 COG0791@1|root,COG5263@1|root,COG0791@2|Bacteria,COG5263@2|Bacteria,1UWMK@1239|Firmicutes,4I2FR@91061|Bacilli,43GKC@68892|Streptococcus infantis 91061|Bacilli M Putative cell wall binding repeat - - - - - - - - - - - - CW_binding_1 NFINBLID_02009 388919.SSA_0161 1.5e-133 413.0 COG3451@1|root,COG3451@2|Bacteria,1TS2J@1239|Firmicutes,4HYWU@91061|Bacilli,1WS2P@1305|Streptococcus sanguinis 91061|Bacilli U AAA-like domain - - - - - - - - - - - - DUF87 NFINBLID_02012 176090.SSIN_1294 1e-35 121.0 2ETKC@1|root,33M40@2|Bacteria,1VPN1@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - NFINBLID_02013 176090.SSIN_1295 8.96e-126 360.0 COG2184@1|root,COG2184@2|Bacteria 2|Bacteria D nucleotidyltransferase activity fic - - ko:K04095 - - - - ko00000,ko03036 - - - Fic NFINBLID_02015 388919.SSA_0158 1.98e-53 189.0 29RP1@1|root,30CSB@2|Bacteria,1UAAE@1239|Firmicutes,4IKMZ@91061|Bacilli,1WS13@1305|Streptococcus sanguinis 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_02017 388919.SSA_0156 3.81e-158 476.0 COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,4HACY@91061|Bacilli,1WS1P@1305|Streptococcus sanguinis 91061|Bacilli O C-terminal, D2-small domain, of ClpB protein - - - ko:K03696 ko01100,map01100 - - - ko00000,ko03110 - - - AAA,AAA_2,ClpB_D2-small NFINBLID_02021 873449.STRCR_1540 5.14e-08 62.0 28Z7V@1|root,2ZKZZ@2|Bacteria,1W1W6@1239|Firmicutes,4I12Y@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_02022 888821.HMPREF9394_0979 0.0 882.0 COG1479@1|root,COG1479@2|Bacteria,1UHG8@1239|Firmicutes 1239|Firmicutes S Protein of unknown function DUF262 - - - - - - - - - - - - DUF1524,DUF262 NFINBLID_02023 999425.HMPREF9186_00942 5.66e-129 366.0 COG4283@1|root,COG4283@2|Bacteria,1V8M5@1239|Firmicutes 1239|Firmicutes S cog cog4283 - - - - - - - - - - - - DUF1706 NFINBLID_02024 944565.HMPREF9127_0007 1.44e-92 276.0 COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia 186801|Clostridia K Psort location Cytoplasmic, score - - - - - - - - - - - - GyrI-like NFINBLID_02025 411465.PEPMIC_00202 5.4e-164 464.0 COG2378@1|root,COG2378@2|Bacteria,1TS78@1239|Firmicutes,25C7I@186801|Clostridia,22IA1@1570339|Peptoniphilaceae 186801|Clostridia K WYL domain - - - - - - - - - - - - HTH_11,WYL NFINBLID_02026 264199.stu1510 1.5e-07 51.2 COG2253@1|root,COG2253@2|Bacteria 2|Bacteria V Psort location Cytoplasmic, score - - - - - - - - - - - - AbiEii NFINBLID_02027 435842.HMPREF0848_01140 1.22e-102 296.0 COG4405@1|root,COG4405@2|Bacteria,1V6S0@1239|Firmicutes,4HKKR@91061|Bacilli 91061|Bacilli P Protein conserved in bacteria - - - - - - - - - - - - ASCH NFINBLID_02028 888048.HMPREF8577_0144 1.78e-102 298.0 COG1051@1|root,COG1051@2|Bacteria,1V4ND@1239|Firmicutes,4HJ5H@91061|Bacilli 91061|Bacilli F Belongs to the Nudix hydrolase family - - - - - - - - - - - - NUDIX NFINBLID_02029 1005704.HMPREF9968_0308 2.52e-153 436.0 COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,4HGAF@91061|Bacilli 91061|Bacilli S Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - - - - - - - - - - AbiEii NFINBLID_02030 264199.stu1509 6.75e-138 390.0 COG5340@1|root,COG5340@2|Bacteria,1V3JU@1239|Firmicutes,4HMVW@91061|Bacilli 91061|Bacilli K Transcriptional regulator, AbiEi antitoxin - - - - - - - - - - - - AbiEi_4 NFINBLID_02038 1114965.Spaf_0980 2.3e-39 142.0 COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,4HB1W@91061|Bacilli 91061|Bacilli E Belongs to the UPF0758 family radC - - ko:K03630 - - - - ko00000 - - - RadC NFINBLID_02044 1069533.Sinf_0777 1.12e-80 251.0 COG1074@1|root,COG1074@2|Bacteria,1V1UQ@1239|Firmicutes,4HGSG@91061|Bacilli 91061|Bacilli L PDDEXK-like domain of unknown function (DUF3799) pi112 - - - - - - - - - - - DUF3799 NFINBLID_02045 349123.Lreu23DRAFT_3089 5.57e-44 149.0 COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,4HH8I@91061|Bacilli,3F66N@33958|Lactobacillaceae 91061|Bacilli L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism ssb - - ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 - - - ko00000,ko00001,ko03029,ko03032,ko03400 - - - SSB NFINBLID_02046 888049.HMPREF8578_0412 0.0 875.0 COG2114@1|root,COG2114@2|Bacteria,1VWRR@1239|Firmicutes 1239|Firmicutes T Pfam Adenylate and Guanylate cyclase catalytic domain - - - - - - - - - - - - - NFINBLID_02047 888049.HMPREF8578_0413 1.42e-108 313.0 COG2856@1|root,COG2856@2|Bacteria 2|Bacteria E Zn peptidase immA - - - - - - - - - - - Peptidase_M78 NFINBLID_02049 1297534.CAUJ01000006_gene239 1.82e-14 84.7 COG3583@1|root,COG3583@2|Bacteria 2|Bacteria S pathogenesis zmpB - - ko:K08643 - - - - ko00000,ko01000,ko01002 - - - Excalibur,G5,Peptidase_M26_C,Peptidase_M26_N,YSIRK_signal NFINBLID_02050 388919.SSA_0265 1.61e-28 106.0 COG2963@1|root,COG2963@2|Bacteria,1W68S@1239|Firmicutes,4I47X@91061|Bacilli,1WS1X@1305|Streptococcus sanguinis 91061|Bacilli L IS861 transposase - - - - - - - - - - - - - NFINBLID_02051 904294.HMPREF9182_1299 2.38e-68 208.0 COG2963@1|root,COG2963@2|Bacteria,1VDX9@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_28,HTH_Tnp_1 NFINBLID_02052 322159.STER_1694 0.0 952.0 COG1132@1|root,COG1132@2|Bacteria,1VBVE@1239|Firmicutes 1239|Firmicutes V ABC transporter transmembrane region - - - - - - - - - - - - ABC_membrane,ABC_tran NFINBLID_02057 322159.STER_1693 2.95e-185 517.0 COG1396@1|root,COG1396@2|Bacteria,1VIH9@1239|Firmicutes,4HQ23@91061|Bacilli 91061|Bacilli K Helix-turn-helix XRE-family like proteins - - - - - - - - - - - - HTH_3 NFINBLID_02058 435842.HMPREF0848_00089 1.35e-71 231.0 COG1705@1|root,COG3942@1|root,COG1705@2|Bacteria,COG3942@2|Bacteria,1UIWC@1239|Firmicutes,4ISUH@91061|Bacilli 91061|Bacilli NU GBS Bsp-like repeat - - - - - - - - - - - - CHAP,GBS_Bsp-like,SH3_5,YSIRK_signal NFINBLID_02059 435842.HMPREF0848_00089 7.5e-14 72.4 COG1705@1|root,COG3942@1|root,COG1705@2|Bacteria,COG3942@2|Bacteria,1UIWC@1239|Firmicutes,4ISUH@91061|Bacilli 91061|Bacilli NU GBS Bsp-like repeat - - - - - - - - - - - - CHAP,GBS_Bsp-like,SH3_5,YSIRK_signal NFINBLID_02066 388919.SSA_0152 8.24e-147 469.0 COG3505@1|root,COG3505@2|Bacteria,1V0JC@1239|Firmicutes,4HAST@91061|Bacilli,1WS19@1305|Streptococcus sanguinis 91061|Bacilli U TraM recognition site of TraD and TraG - - - - - - - - - - - - T4SS-DNA_transf,TraG-D_C NFINBLID_02068 888816.HMPREF9389_0702 4.4e-21 102.0 29RPN@1|root,30CT3@2|Bacteria,1UABH@1239|Firmicutes,4IKPN@91061|Bacilli,1WS3H@1305|Streptococcus sanguinis 91061|Bacilli S Ribosomal protein S1-like RNA-binding domain - - - - - - - - - - - - - NFINBLID_02069 210007.SMU_1301c 5.65e-132 379.0 COG0500@1|root,COG2226@2|Bacteria,1TSVN@1239|Firmicutes,4HBRU@91061|Bacilli 91061|Bacilli Q Methyltransferase ubiE - - - - - - - - - - - Methyltransf_11,Methyltransf_25,Methyltransf_31 NFINBLID_02071 768726.HMPREF9178_0212 0.0 2120.0 COG0823@1|root,COG5492@1|root,COG0823@2|Bacteria,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,4IU56@91061|Bacilli 91061|Bacilli N Leucine rich repeats (6 copies) - - - - - - - - - - - - Big_3,Cadherin-like,DUF5011,Flg_new,LRR_5,SLH,fn3,ubiquitin NFINBLID_02072 1095726.HMPREF1116_0749 9.19e-62 206.0 COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,4HK9Z@91061|Bacilli 91061|Bacilli F DNA RNA non-specific endonuclease spd - - ko:K15051 - - - - ko00000 - - - Endonuclea_NS_2 NFINBLID_02073 1423754.BALY01000055_gene1820 1.05e-21 102.0 COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,4HANE@91061|Bacilli,3F3P9@33958|Lactobacillaceae 91061|Bacilli L Belongs to the 'phage' integrase family xerS - - ko:K03733 - - - - ko00000,ko03036 - - - Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase NFINBLID_02076 1158607.UAU_05287 8.94e-24 104.0 COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,4HAYM@91061|Bacilli,4B4XU@81852|Enterococcaceae 91061|Bacilli D Cellulose biosynthesis protein BcsQ - - - ko:K03496 - - - - ko00000,ko03036,ko04812 - - - AAA_31 NFINBLID_02078 996306.SSUR61_0081 5.61e-92 273.0 28JJY@1|root,2Z9CV@2|Bacteria,1U8YB@1239|Firmicutes,4IIXR@91061|Bacilli,1WSV0@1307|Streptococcus suis 91061|Bacilli S Region found in RelA / SpoT proteins - - - - - - - - - - - - RelA_SpoT NFINBLID_02079 1121865.OMW_00624 1.47e-17 94.0 2EYQW@1|root,33RY9@2|Bacteria,1VSR7@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - NFINBLID_02080 1154860.SAG0136_08385 2.36e-46 164.0 COG2804@1|root,COG2804@2|Bacteria,1TPGE@1239|Firmicutes,4HB0C@91061|Bacilli 91061|Bacilli NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB comGA - - ko:K02243 - M00429 - - ko00000,ko00002,ko02044 3.A.14.1 - - T2SSE NFINBLID_02082 997830.HMPREF1124_0583 9.1e-60 211.0 28KSN@1|root,2Z9PR@2|Bacteria,1TSZJ@1239|Firmicutes,4HQ11@91061|Bacilli,43GFS@68892|Streptococcus infantis 91061|Bacilli S the current gene model (or a revised gene model) may contain a frame shift - - - - - - - - - - - - PcfJ NFINBLID_02085 1282664.H354_05021 0.0 1552.0 COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,4HDHN@91061|Bacilli 91061|Bacilli L the current gene model (or a revised gene model) may contain a XK27_00500 - - - - - - - - - - - Helicase_C,N6_Mtase,ResIII,SNF2_N NFINBLID_02086 904294.HMPREF9182_1249 1.94e-255 704.0 COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,4IPIE@91061|Bacilli 91061|Bacilli L Transposase IS116 IS110 IS902 - - - - - - - - - - - - DEDD_Tnp_IS110,Transposase_20 NFINBLID_02087 1316408.HSISM1_1539 1.99e-162 459.0 COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,4HC8M@91061|Bacilli 91061|Bacilli L Transposase and inactivated derivatives - - - ko:K07497 - - - - ko00000 - - - HTH_21,HTH_28,rve,rve_2 NFINBLID_02088 388919.SSA_0265 5.66e-29 107.0 COG2963@1|root,COG2963@2|Bacteria,1W68S@1239|Firmicutes,4I47X@91061|Bacilli,1WS1X@1305|Streptococcus sanguinis 91061|Bacilli L IS861 transposase - - - - - - - - - - - - - NFINBLID_02089 904294.HMPREF9182_1299 9.46e-57 179.0 COG2963@1|root,COG2963@2|Bacteria,1VDX9@1239|Firmicutes 1239|Firmicutes L Transposase - - - ko:K07483 - - - - ko00000 - - - HTH_28,HTH_Tnp_1 NFINBLID_02091 179408.Osc7112_3904 2.29e-06 58.2 COG0457@1|root,COG0463@1|root,COG0457@2|Bacteria,COG0463@2|Bacteria,1G0II@1117|Cyanobacteria,1H8SJ@1150|Oscillatoriales 1117|Cyanobacteria M PFAM Glycosyl transferase family 2 - - - - - - - - - - - - Glycos_transf_2,TPR_1,TPR_16,TPR_2,TPR_8 NFINBLID_02092 889201.HMPREF9422_1125 1.47e-209 613.0 COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli 91061|Bacilli V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain comA GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 - - - ko00000,ko00001,ko01000,ko02000 3.A.1,3.A.1.112,3.A.1.112.1 - - ABC_membrane,ABC_tran,Peptidase_C39 NFINBLID_02093 888816.HMPREF9389_1289 4.4e-58 188.0 COG4469@1|root,COG4469@2|Bacteria,1TRGD@1239|Firmicutes,4HFP5@91061|Bacilli,1WR4E@1305|Streptococcus sanguinis 91061|Bacilli S Competence protein coiA - - ko:K06198 - - - - ko00000 - - - CoiA NFINBLID_02094 1046629.Ssal_02110 4.82e-238 654.0 COG2826@1|root,COG2826@2|Bacteria,1TRSF@1239|Firmicutes,4HDM3@91061|Bacilli 91061|Bacilli L PFAM Integrase, catalytic core - - - ko:K07482 - - - - ko00000 - - - HTH_38,rve NFINBLID_02096 888048.HMPREF8577_1852 1.6e-99 307.0 COG0860@1|root,COG0860@2|Bacteria 2|Bacteria M N-Acetylmuramoyl-L-alanine amidase amiB GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 ko:K01448 ko01503,map01503 M00727 R04112 RC00064,RC00141 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 - - iG2583_1286.G2583_4996 AMIN,Amidase_3,LysM NFINBLID_02097 1046629.Ssal_00994 5.74e-129 367.0 COG1670@1|root,COG1670@2|Bacteria,1V3NE@1239|Firmicutes,4HG1N@91061|Bacilli 91061|Bacilli J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - ko:K03817 - - - - ko00000,ko01000,ko03009 - - - Acetyltransf_3 NFINBLID_02098 904306.HMPREF9192_1827 2.72e-238 655.0 COG1064@1|root,COG1064@2|Bacteria,1TP5B@1239|Firmicutes,4HA9Z@91061|Bacilli 91061|Bacilli C alcohol dehydrogenase adhP - 1.1.1.1 ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 - R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310 RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273 ko00000,ko00001,ko01000 - - - ADH_N,ADH_zinc_N NFINBLID_02099 904306.HMPREF9192_1828 3.43e-59 182.0 2E660@1|root,330UP@2|Bacteria,1VFJD@1239|Firmicutes 1239|Firmicutes - - - - - - - - - - - - - - - NFINBLID_02100 435842.HMPREF0848_00770 4.32e-68 207.0 2E59Z@1|root,33028@2|Bacteria,1VFMU@1239|Firmicutes,4HQG9@91061|Bacilli 91061|Bacilli - - - - - - - - - - - - - - - NFINBLID_02101 904306.HMPREF9192_1830 0.0 909.0 COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,4HA1P@91061|Bacilli 91061|Bacilli L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII polYB - 2.7.7.7 ko:K02346,ko:K03502 - - - - ko00000,ko01000,ko03400 - - - IMS,IMS_C,IMS_HHH NFINBLID_02102 1046629.Ssal_00988 1.24e-199 553.0 COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes 1239|Firmicutes ET ABC transporter substrate-binding protein aatB - - ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - SBP_bac_3 NFINBLID_02103 1046629.Ssal_00987 8.75e-145 408.0 COG1126@1|root,COG1126@2|Bacteria,1UYAZ@1239|Firmicutes,4HE6M@91061|Bacilli 91061|Bacilli E abc transporter atp-binding protein glnQ - 3.6.3.21 ko:K02028 - M00236 - - ko00000,ko00002,ko01000,ko02000 3.A.1.3 - - ABC_tran NFINBLID_02104 264199.stu0875 1.67e-135 385.0 COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,4HGMH@91061|Bacilli 91061|Bacilli P ABC transporter (Permease yecS_2 - - ko:K02029,ko:K02030 - M00236 - - ko00000,ko00002,ko02000 3.A.1.3 - - BPD_transp_1 NFINBLID_02105 1046629.Ssal_00985 7.1e-78 231.0 COG2824@1|root,COG2824@2|Bacteria,1V6NA@1239|Firmicutes,4HIKN@91061|Bacilli 91061|Bacilli P Alkylphosphonate utilization operon protein PhnA phnA - - ko:K06193 ko01120,map01120 - - - ko00000 - - - PhnA,PhnA_Zn_Ribbon NFINBLID_02106 1046629.Ssal_00983 0.0 1158.0 COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,4H9R4@91061|Bacilli 91061|Bacilli M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source glmS GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 - R00768 RC00010,RC00163,RC02752 ko00000,ko00001,ko01000,ko01002 - - iSB619.SA_RS11245,iYO844.BSU01780 GATase_6,SIS NFINBLID_02107 1046629.Ssal_00982 1.47e-212 587.0 COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,4HC5J@91061|Bacilli 91061|Bacilli K Transcriptional regulator cpsY - - - - - - - - - - - HTH_1,LysR_substrate NFINBLID_02108 1046629.Ssal_00980 2.29e-163 457.0 COG1705@1|root,COG1705@2|Bacteria,1UYRM@1239|Firmicutes,4HAU6@91061|Bacilli 91061|Bacilli NU muramidase - - - ko:K02395,ko:K19223 - - - - ko00000,ko01000,ko01002,ko01011,ko02035 - CBM50 - Glucosaminidase,LysM NFINBLID_02109 1046629.Ssal_00979 8.74e-217 601.0 COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes 1239|Firmicutes S Membrane yeiH - - - - - - - - - - - Cons_hypoth698 NFINBLID_02111 1046629.Ssal_00976 0.0 1014.0 COG0803@1|root,COG3443@1|root,COG0803@2|Bacteria,COG3443@2|Bacteria,1TPG7@1239|Firmicutes,4H9UN@91061|Bacilli 91061|Bacilli P Belongs to the bacterial solute-binding protein 9 family adcA - - ko:K09815 ko02010,map02010 M00242 - - ko00000,ko00001,ko00002,ko02000 3.A.1.15.3,3.A.1.15.5 - - ZinT,ZnuA NFINBLID_02112 1046629.Ssal_00975 2.65e-180 503.0 COG2339@1|root,COG2339@2|Bacteria 2|Bacteria D peptidase activity XK27_10720 - - - - - - - - - - - PrsW-protease NFINBLID_02113 1046629.Ssal_00974 0.0 954.0 COG4690@1|root,COG4690@2|Bacteria,1TQ0F@1239|Firmicutes,4HC3G@91061|Bacilli 91061|Bacilli E Dipeptidase pepD - - ko:K08659 - - - - ko00000,ko01000,ko01002 - - - Peptidase_C69 NFINBLID_02114 1046629.Ssal_00973 6.93e-207 573.0 COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,4HB4H@91061|Bacilli 91061|Bacilli K May be required for sporulation whiA GO:0008150,GO:0043937,GO:0050789,GO:0050793,GO:0065007 - ko:K09762 - - - - ko00000 - - - HTH_WhiA,LAGLIDADG_WhiA,WhiA_N NFINBLID_02115 1046629.Ssal_00972 5.04e-231 636.0 COG0391@1|root,COG0391@2|Bacteria,1TPNV@1239|Firmicutes,4HA0Z@91061|Bacilli 91061|Bacilli S Required for morphogenesis under gluconeogenic growth conditions yvcK - - - - - - - - - - - UPF0052 NFINBLID_02116 1046629.Ssal_00971 5.72e-207 573.0 COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,4H9KM@91061|Bacilli 91061|Bacilli S Displays ATPase and GTPase activities yvcJ - - ko:K06958 - - - - ko00000,ko03019 - - - ATP_bind_2 NFINBLID_02117 1046629.Ssal_00970 2.46e-172 482.0 COG4420@1|root,COG4420@2|Bacteria,1V46X@1239|Firmicutes,4HI49@91061|Bacilli 91061|Bacilli S cyclic nucleotide-binding protein yejC - - - - - - - - - - - DUF1003 NFINBLID_02118 1046629.Ssal_00969 2.71e-313 874.0 COG1196@1|root,COG1196@2|Bacteria 2|Bacteria D nuclear chromosome segregation - - - - - - - - - - - - DUF4297,PhageMin_Tail NFINBLID_02119 904306.HMPREF9192_1256 5.6e-123 349.0 COG0780@1|root,COG0780@2|Bacteria,1TPYC@1239|Firmicutes,4HB14@91061|Bacilli 91061|Bacilli S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily queF - 1.7.1.13 ko:K09457 ko00790,ko01100,map00790,map01100 - R07605 RC01875 ko00000,ko00001,ko01000,ko03016 - - - QueF NFINBLID_02120 904306.HMPREF9192_1255 7.47e-174 484.0 COG0602@1|root,COG0602@2|Bacteria,1TQ58@1239|Firmicutes,4HAJ3@91061|Bacilli 91061|Bacilli H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds queE GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 ko:K10026 ko00790,ko01100,map00790,map01100 - R10002 RC02989 ko00000,ko00001,ko01000,ko03016 - - - Fer4_12,Fer4_14,Radical_SAM NFINBLID_02121 1046629.Ssal_00964 3.92e-104 300.0 COG0720@1|root,COG0720@2|Bacteria,1V9HU@1239|Firmicutes,4HJEX@91061|Bacilli 91061|Bacilli H synthase queD - 4.1.2.50,4.2.3.12 ko:K01737 ko00790,ko01100,map00790,map01100 M00842,M00843 R04286,R09959 RC01117,RC02846,RC02847 ko00000,ko00001,ko00002,ko01000,ko03016 - - - PTPS NFINBLID_02122 1046629.Ssal_00963 1.3e-159 446.0 COG0603@1|root,COG0603@2|Bacteria,1TP4Z@1239|Firmicutes,4HB1Y@91061|Bacilli 91061|Bacilli F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) queC - 6.3.4.20 ko:K06920 ko00790,ko01100,map00790,map01100 - R09978 RC00959 ko00000,ko00001,ko01000,ko03016 - - - QueC NFINBLID_02123 1046629.Ssal_00962 9.11e-84 247.0 COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,4HKEF@91061|Bacilli 91061|Bacilli J endoribonuclease L-PSP aldR - 3.5.99.10 ko:K09022 - - R11098,R11099 RC03275,RC03354 ko00000,ko01000 - - - Ribonuc_L-PSP NFINBLID_02124 888833.HMPREF9421_1356 4.04e-252 696.0 COG0477@1|root,COG2814@2|Bacteria,1V6VB@1239|Firmicutes,4IT0A@91061|Bacilli 91061|Bacilli EGP Major Facilitator Superfamily pmrB - - - - - - - - - - - MFS_1 NFINBLID_02126 904306.HMPREF9192_1250 0.0 904.0 COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,4H9YH@91061|Bacilli 91061|Bacilli J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA asnS GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 ko:K01893 ko00970,map00970 M00359,M00360 R03648 RC00055,RC00523 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 - - - tRNA-synt_2,tRNA_anti-codon NFINBLID_02127 264199.stu0817 1.18e-273 749.0 COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,4HA13@91061|Bacilli 91061|Bacilli E Aminotransferase aspB GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 - R00355,R00694,R00734,R00896,R01346,R02433,R02619,R05052 RC00006,RC00025 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_1_2 NFINBLID_02128 1046629.Ssal_00958 1.94e-99 290.0 COG5353@1|root,COG5353@2|Bacteria,1VA2H@1239|Firmicutes,4HNMM@91061|Bacilli 91061|Bacilli S Protein conserved in bacteria ypmB - - - - - - - - - - - PepSY NFINBLID_02129 1046629.Ssal_00957 0.0 1548.0 COG1199@1|root,COG2176@1|root,COG1199@2|Bacteria,COG2176@2|Bacteria,1TQHQ@1239|Firmicutes,4HB2Y@91061|Bacilli 91061|Bacilli L helicase involved in DNA repair and perhaps also replication dinG GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 3.6.4.12 ko:K03722 - - - - ko00000,ko01000,ko03400 - - - DEAD,Helicase_C_2,RNase_T,ResIII NFINBLID_02130 1046629.Ssal_00954 5.91e-146 411.0 COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,4HHRQ@91061|Bacilli 91061|Bacilli S COG0491 Zn-dependent hydrolases, including glyoxylases yqgX - 3.1.2.6 ko:K01069 ko00620,map00620 - R01736 RC00004,RC00137 ko00000,ko00001,ko01000 - - - Lactamase_B NFINBLID_02131 1046629.Ssal_00953 6.73e-217 600.0 COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,4HAX4@91061|Bacilli 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family yufQ - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 NFINBLID_02132 435842.HMPREF0848_00801 9.03e-236 650.0 COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,4H9VE@91061|Bacilli 91061|Bacilli S Belongs to the binding-protein-dependent transport system permease family mglC - - ko:K02057 - M00221 - - ko00000,ko00002,ko02000 3.A.1.2 - - BPD_transp_2 NFINBLID_02133 435842.HMPREF0848_00802 0.0 963.0 COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,4HVSH@91061|Bacilli 91061|Bacilli S ABC transporter, ATP-binding protein mglA - 3.6.3.17 ko:K02056,ko:K06400 - M00221 - - ko00000,ko00002,ko01000,ko02000 3.A.1.2 - - ABC_tran NFINBLID_02134 1046629.Ssal_00950 5.75e-244 671.0 COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,4HF7R@91061|Bacilli 91061|Bacilli S membrane - - - ko:K07335 - - - - ko00000 - - - Bmp NFINBLID_02135 1046629.Ssal_00949 1.73e-84 249.0 COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,4HIJ3@91061|Bacilli 91061|Bacilli F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis cdd - 3.5.4.5 ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01878,R02485,R08221 RC00074,RC00514 ko00000,ko00001,ko01000 - - - dCMP_cyt_deam_1 NFINBLID_02136 1046629.Ssal_00948 4.78e-143 405.0 COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,4HAAJ@91061|Bacilli 91061|Bacilli F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate deoC GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 ko:K01619 ko00030,map00030 - R01066 RC00436,RC00437 ko00000,ko00001,ko01000 - - iSB619.SA_RS00835 DeoC NFINBLID_02137 1046629.Ssal_00947 2.45e-290 795.0 COG0213@1|root,COG0213@2|Bacteria,1TPCH@1239|Firmicutes,4H9NP@91061|Bacilli 91061|Bacilli F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate pdp GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 ko:K00756 ko00240,ko01100,map00240,map01100 - R01570,R01876,R02296,R02484 RC00063 ko00000,ko00001,ko01000 - - - Glycos_trans_3N,Glycos_transf_3,PYNP_C NFINBLID_02138 1046629.Ssal_00946 3.21e-136 385.0 COG2813@1|root,COG2813@2|Bacteria,1V3JX@1239|Firmicutes,4IR00@91061|Bacilli 91061|Bacilli J Methyltransferase small domain protein rsmC - 2.1.1.172 ko:K00564 - - R07234 RC00003 ko00000,ko01000,ko03009 - - - MTS NFINBLID_02139 1046629.Ssal_00945 4.78e-220 607.0 COG1072@1|root,COG1072@2|Bacteria,1TPHJ@1239|Firmicutes,4HA4K@91061|Bacilli 91061|Bacilli F Pantothenic acid kinase coaA GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 ko:K00867 ko00770,ko01100,map00770,map01100 M00120 R02971,R03018,R04391 RC00002,RC00017 ko00000,ko00001,ko00002,ko01000 - - - PRK NFINBLID_02140 1046629.Ssal_00944 4.36e-40 133.0 COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,4HNJS@91061|Bacilli 91061|Bacilli J Binds directly to 16S ribosomal RNA rpsT - - ko:K02968 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_S20p NFINBLID_02141 904306.HMPREF9192_1234 5.01e-310 848.0 COG0642@1|root,COG2205@2|Bacteria,1UHNC@1239|Firmicutes,4IS4A@91061|Bacilli 91061|Bacilli T Histidine kinase ciaH - 2.7.13.3 ko:K14982 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 - - - HATPase_c,HisKA NFINBLID_02142 1046629.Ssal_00942 2.39e-154 434.0 COG0745@1|root,COG0745@2|Bacteria,1V295@1239|Firmicutes,4HG3X@91061|Bacilli 91061|Bacilli T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain ciaR - - ko:K14983 ko02020,ko02024,map02020,map02024 M00521 - - ko00000,ko00001,ko00002,ko02022 - - - Response_reg,Trans_reg_C NFINBLID_02143 1046629.Ssal_00941 0.0 1090.0 COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,4HA2X@91061|Bacilli 91061|Bacilli F Belongs to the formate--tetrahydrofolate ligase family fhs - 6.3.4.3 ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 M00140,M00377 R00943 RC00026,RC00111 ko00000,ko00001,ko00002,ko01000 - - - FTHFS NFINBLID_02144 1046629.Ssal_00940 2.77e-150 424.0 COG0452@1|root,COG0452@2|Bacteria,1V7YG@1239|Firmicutes,4HMIF@91061|Bacilli 91061|Bacilli H Phosphopantothenate-cysteine ligase coaB - 6.3.2.5 ko:K21977 ko00770,map00770 M00120 R04231 RC00064,RC00090 ko00000,ko00001,ko00002,ko01000 - - - DFP NFINBLID_02145 1046629.Ssal_00939 2.12e-120 344.0 COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,4HAK8@91061|Bacilli 91061|Bacilli H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine coaBC - 4.1.1.36,6.3.2.5 ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 M00120 R03269,R04231 RC00064,RC00090,RC00822 ko00000,ko00001,ko00002,ko01000 - - - DFP,Flavoprotein NFINBLID_02146 1046629.Ssal_00938 3.72e-121 347.0 COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,4HFPD@91061|Bacilli 91061|Bacilli S ECF transporter, substrate-specific component - - - - - - - - - - - - ECF_trnsprt NFINBLID_02147 1046629.Ssal_00936 1.21e-117 338.0 COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes 1239|Firmicutes S Psort location CytoplasmicMembrane, score - - - - - - - - - - - - ECF_trnsprt NFINBLID_02148 1046629.Ssal_00935 0.0 1116.0 COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,4HADU@91061|Bacilli 91061|Bacilli G Phosphoglucomutase pgm - 5.4.2.2 ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 M00549 R00959,R01057,R08639 RC00408 ko00000,ko00001,ko00002,ko01000 - - - PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV NFINBLID_02149 1046629.Ssal_00934 5.14e-212 585.0 COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes 1239|Firmicutes E reductase metF - 1.5.1.20 ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 M00377 R01224,R07168 RC00081 ko00000,ko00001,ko00002,ko01000 - - - MTHFR NFINBLID_02150 1046629.Ssal_00933 0.0 1481.0 COG0620@1|root,COG0620@2|Bacteria,1TP2H@1239|Firmicutes,4H9QC@91061|Bacilli 91061|Bacilli E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation metE GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 M00017 R04405,R09365 RC00035,RC00113,RC01241 ko00000,ko00001,ko00002,ko01000 - - - Meth_synt_1,Meth_synt_2 NFINBLID_02152 1046629.Ssal_00931 0.0 1095.0 COG0115@1|root,COG0147@1|root,COG0115@2|Bacteria,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,4HBKC@91061|Bacilli 91061|Bacilli EH component I pabB - 2.6.1.85,4.1.3.38 ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 - R01716,R05553 RC00010,RC01418,RC01843,RC02148 ko00000,ko00001,ko01000,ko01007 - - - Aminotran_4,Chorismate_bind NFINBLID_02153 1046629.Ssal_00930 0.0 1635.0 COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,4H9S5@91061|Bacilli 91061|Bacilli P cation transport ATPase - - 3.6.3.2,3.6.3.6,3.6.3.8 ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 - - - ko00000,ko00001,ko01000 3.A.3.2,3.A.3.3,3.A.3.4 - - Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3 NFINBLID_02154 1046629.Ssal_00929 1.9e-296 810.0 COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,4HC3H@91061|Bacilli 91061|Bacilli M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) dltD - - ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - DltD NFINBLID_02155 1046629.Ssal_00928 7.07e-48 153.0 COG0236@1|root,COG0236@2|Bacteria,1VFQI@1239|Firmicutes,4HNIH@91061|Bacilli 91061|Bacilli IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltC GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - PP-binding NFINBLID_02156 1046629.Ssal_00927 1.2e-300 820.0 COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,4HBQG@91061|Bacilli 91061|Bacilli M Membrane protein involved in D-alanine export dltB - - ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 M00725 - - ko00000,ko00001,ko00002,ko01504 - - - MBOAT NFINBLID_02157 1046629.Ssal_00926 0.0 1020.0 COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,4HAHU@91061|Bacilli 91061|Bacilli Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall dltA GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 M00725 R02718 RC00037,RC00094 ko00000,ko00001,ko00002,ko01000,ko01504 - - - AMP-binding,AMP-binding_C NFINBLID_02158 1046629.Ssal_00924 0.0 1089.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4HCVN@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein XK27_10035 - - ko:K06147 - - - - ko00000,ko02000 3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NFINBLID_02159 904306.HMPREF9192_1216 0.0 1012.0 COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,4H9SC@91061|Bacilli 91061|Bacilli V abc transporter atp-binding protein yfiB1 - - ko:K06147,ko:K06148 - - - - ko00000,ko02000 3.A.1,3.A.1.106,3.A.1.109,3.A.1.21 - - ABC_membrane,ABC_tran NFINBLID_02160 435842.HMPREF0848_00829 4.21e-124 355.0 COG0741@1|root,COG0741@2|Bacteria 2|Bacteria M lytic transglycosylase activity pvaA - - ko:K02395 - - - - ko00000,ko02035 - - - Lysozyme_like,SLT_2 NFINBLID_02161 904306.HMPREF9192_1214 2.13e-228 629.0 COG3081@1|root,COG3081@2|Bacteria,1V437@1239|Firmicutes,4IQXJ@91061|Bacilli 91061|Bacilli S 37-kD nucleoid-associated bacterial protein - - - - - - - - - - - - NA37 NFINBLID_02162 904306.HMPREF9192_1213 3.81e-293 801.0 COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,4HA5K@91061|Bacilli 91061|Bacilli E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism glyA - 2.1.2.1 ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 M00140,M00141,M00346,M00532 R00945,R09099 RC00022,RC00112,RC01583,RC02958 ko00000,ko00001,ko00002,ko01000 - - - SHMT NFINBLID_02163 1046629.Ssal_00919 1.19e-131 374.0 COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,4HA7W@91061|Bacilli 91061|Bacilli J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine ywlC GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 ko:K07566 - - R10463 RC00745 ko00000,ko01000,ko03009,ko03016 - - - SUA5,Sua5_yciO_yrdC NFINBLID_02164 1046629.Ssal_00918 3.93e-184 513.0 COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,4HC6W@91061|Bacilli 91061|Bacilli J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif prmC GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 ko:K02493 - - R10806 RC00003,RC03279 ko00000,ko01000,ko03012 - - - MTS NFINBLID_02165 1046629.Ssal_00917 4.58e-247 679.0 COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,4H9MB@91061|Bacilli 91061|Bacilli J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA prfA - - ko:K02835 - - - - ko00000,ko03012 - - - PCRF,RF-1 NFINBLID_02166 904306.HMPREF9192_1209 7.01e-141 397.0 COG1435@1|root,COG1435@2|Bacteria,1TRVM@1239|Firmicutes,4HA4A@91061|Bacilli 91061|Bacilli F thymidine kinase tdk GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 - R01567,R02099,R08233 RC00002,RC00017 ko00000,ko00001,ko01000 - - - TK NFINBLID_02167 904306.HMPREF9192_1208 1.28e-230 636.0 COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,4HCES@91061|Bacilli 91061|Bacilli F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism add - 3.5.4.2,3.5.4.4 ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 M00236 R01244,R01560,R02556 RC00477 ko00000,ko00001,ko00002,ko01000,ko02000 3.A.1.3 - - A_deaminase NFINBLID_02168 1046629.Ssal_00914 2.52e-193 535.0 COG0625@1|root,COG0625@2|Bacteria,1TPZ7@1239|Firmicutes,4HD0K@91061|Bacilli 91061|Bacilli O Glutathione S-transferase gst - - ko:K11209 - - - - ko00000,ko01000 - - - GST_C,GST_C_2,GST_N,GST_N_2 NFINBLID_02169 1046629.Ssal_00913 1.18e-224 619.0 COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,4H9ZW@91061|Bacilli 91061|Bacilli S domain protein nrnA - 3.1.13.3,3.1.3.7 ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 - R00188,R00508 RC00078 ko00000,ko00001,ko01000,ko03400 - - - DHH,DHHA1 NFINBLID_02170 904306.HMPREF9192_1205 2.85e-214 592.0 COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,4HDFE@91061|Bacilli 91061|Bacilli H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein apbE - 2.7.1.180 ko:K03734 - - - - ko00000,ko01000 - - - ApbE NFINBLID_02171 1046629.Ssal_00910 3.52e-61 187.0 COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,4HNQF@91061|Bacilli 91061|Bacilli J 50S ribosomal protein L31 rpmE - - ko:K02909 ko03010,map03010 M00178 - - br01610,ko00000,ko00001,ko00002,ko03011 - - - Ribosomal_L31 NFINBLID_02172 1046629.Ssal_00908 6.07e-292 798.0 COG1914@1|root,COG1914@2|Bacteria,1V04N@1239|Firmicutes,4HBF6@91061|Bacilli 91061|Bacilli P Mn2 and Fe2 transporters of the NRAMP family mntH_2 - - - - - - - - - - - Nramp NFINBLID_02173 1046629.Ssal_00907 3e-206 573.0 COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,4HBVZ@91061|Bacilli 91061|Bacilli S secreted protein ypuA - - - - - - - - - - - DUF1002 NFINBLID_02174 1046629.Ssal_00906 1.29e-94 275.0 COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,4HIFI@91061|Bacilli 91061|Bacilli E COG0346 Lactoylglutathione lyase and related lyases ywkD - - ko:K08234 - - - - ko00000 - - - Glyoxalase NFINBLID_02175 1046629.Ssal_00905 2.97e-167 469.0 COG3764@1|root,COG3764@2|Bacteria,1V83Z@1239|Firmicutes,4HIA0@91061|Bacilli 91061|Bacilli M Sortase (surface protein transpeptidase) srtA - 3.4.22.70 ko:K07284 - - - - ko00000,ko01000,ko01002,ko01011 - - - Sortase NFINBLID_02176 1046629.Ssal_00904 0.0 1462.0 COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,4HAHY@91061|Bacilli 91061|Bacilli L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner gyrA - 5.99.1.3 ko:K02469 - - - - ko00000,ko01000,ko03032,ko03400 - - - DNA_gyraseA_C,DNA_topoisoIV NFINBLID_02177 1046629.Ssal_00903 2.8e-230 634.0 COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,4HB0Z@91061|Bacilli 91061|Bacilli C Belongs to the LDH MDH superfamily. LDH family ldh - 1.1.1.27 ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 - R00703,R01000,R03104 RC00031,RC00044 ko00000,ko00001,ko01000,ko04147 - - - Ldh_1_C,Ldh_1_N ## 1890 queries scanned ## Total time (seconds): 2.1617729663848877 ## Rate: 874.28 q/s