LOCUS       gnlProkkaCAKJMPPP_29   25933 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CAKJMPPP_29.
ACCESSION   gnlProkkaCAKJMPPP_29
VERSION     gnlProkkaCAKJMPPP_29
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 04:39:13
            Original ID  :: gnl|Prokka|CAKJMPPP_29
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 25933
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..25933
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[9150:12674]"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      9151..12674
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /neighbourhood="20000"
                     /product="HR-T2PKS"
                     /protocluster_number="1"
     cand_cluster    1..25933
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="neighbouring"
                     /product="HR-T2PKS"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..25933
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="HR-T2PKS"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(hr-t2pks-ksa and (t2fas or APE_KS2 or
                     ketoacyl-synt))"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     protocluster    1..10446
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[290:446]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      291..446
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="2"
     cand_cluster    1..10446
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             291..446
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_1"
                     /sec_met_domain="TIGR04223 (E-value: 4.6e-12, bitscore:
                     36.9, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVKNFLGKGVMKCLNVLALLLVMQTANSACIWVAHQPEFPEAAN
                     KFKFNK"
     CDS             624..2240
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059:acetyl-CoA carboxylase, carboxyl transferase,
                     (Score: 420; E-value: 2.5e-127)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_2"
                     /transl_table=11
                     /translation="MTKGRICKACKREIQRDILDANLSVCPFCGYYMRFHAKKRIVSLA
                     DKNSFREWDVNTKWSNPLNDDMYARKLVTTADKHKLDDAIITGEININGEHLAIGVMDS
                     RFMMASMGHIVGERVTSLFERATKKKLPVILFCCSGGARMQEGIISLMQMEKTAAAVKL
                     HSDAGGLYISVLTNPTMGGVTASFATLADIVLAEKGAMIGFAGARVIEQNTGKKLPNGF
                     QTAEFQKEHGFVDMIIERADLRDTLSYFLKLHQKKASLHSGEKKVPEVYVNKRLAQKTA
                     WERVMIARSMNRPTSKDYIDQLFQKFTELSGDRISSDDCAIVGGVAYFRGCPVTVIGHQ
                     KGKGSVEAALYRNWGMPLPQGYRKVMRLAKQAEKFHRPIIFFIDTIGAACGQEAEERGQ
                     GVVIANVLQEMSTLKVPILSIVIGEGGSGGALALGVGNEVWMLENAVYSVLTPESYASI
                     LWKDSSKAQQAAMQMKLEASDLYELGIIDKIIYEEEPVTRDNMEMVCRELENEMITFLM
                     KYLKKTPAGVAKERYRKFRKY"
     CDS             2242..2853
                     /NRPS_PKS="Domain: ACPS (98-150). E-value: 3.8e-06. Score:
                     18.5. Matches aSDomain: nrpspksdomains_ctg29_3_ACPS.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012:4'-phosphopantetheinyl transferase (Score: 86.1;
                     E-value: 3.5e-26)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_3"
                     /transl_table=11
                     /translation="MITVYYFDIEKHRQMLRHESMLREKGKDQKVLREKKQLEMIASEY
                     LKRYVFEEVLHKNYPEELFRGEFGKPYCRDQFCCFNVSGQKDFIVLGLTQKDSIGIDIE
                     KKRELPGTAVGSFFYGNEWDTILNDPKEFTRIWTRKEAFVKCIGTGWKHKPDICVVDDQ
                     ISFDGKKYQIASWEFHDDYVISVCYEDAGYKHQYEMVEVI"
     aSDomain        2536..2691
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg29_3_ACPS.1"
                     /evalue="3.80E-06"
                     /label="ctg29_3_ACPS.1"
                     /locus_tag="ctg29_3"
                     /protein_end="150"
                     /protein_start="98"
                     /score="18.5"
                     /tool="antismash"
                     /translation="IGIDIEKKRELPGTAVGSFFYGNEWDTILNDPKEFTRIWTRKEAF
                     VKCIGTG"
     CDS             2882..3802
                     /NRPS_PKS="Domain: PKS_AT (4-289). E-value: 5.9e-54. Score:
                     175.3. Matches aSDomain: nrpspksdomains_ctg29_4_PKS_AT.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021:malonyl CoA-acyl carrier protein transacylase
                     (Score: 194.7; E-value: 5.2e-59)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_4"
                     /sec_met_domain="PKS_AT (E-value: 3.2e-54, bitscore: 175.3,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAFLFPGQGSQRAGMYELLGDKANETDELFDIAKEATGRDVLSL
                     CKDATDEELKQTYNTQLSVTAMNLAFATLLKHRGVTPDVVAGHSLGQLSALHEAGVLST
                     YDLFRLVNKRAELMSGLKESGKLATILGLEKNVVEAVCEETCQTTDQVRIALENSYKQY
                     VIGGREADVDVAVAKMKEAGALKIVEIRVSNAFHTYMMEPMVEPFKEFINTLDFQEPKT
                     KILLNSKGGYGTSASEIKEDVIRQCVNVVKWEDCMRQMLTLENLTIAEVGVGKMMSSMI
                     RGIDRSQKVYLTSNTNDFNDLAKGV"
     CDS_motif       2891..2932
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg29_4_0001"
                     /evalue="3.80E-06"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ctg29_4"
                     /protein_end="17"
                     /protein_start="3"
                     /score="19.2"
                     /tool="antismash"
                     /translation="FLFPGQGSQRAGMY"
     aSDomain        2894..3748
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg29_4_PKS_AT.1"
                     /evalue="5.90E-54"
                     /label="ctg29_4_PKS_AT.1"
                     /locus_tag="ctg29_4"
                     /protein_end="289"
                     /protein_start="4"
                     /score="175.3"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFPGQGSQRAGMYELLGDKANETDELFDIAKEATGRDVLSLCKDA
                     TDEELKQTYNTQLSVTAMNLAFATLLKHRGVTPDVVAGHSLGQLSALHEAGVLSTYDLF
                     RLVNKRAELMSGLKESGKLATILGLEKNVVEAVCEETCQTTDQVRIALENSYKQYVIGG
                     READVDVAVAKMKEAGALKIVEIRVSNAFHTYMMEPMVEPFKEFINTLDFQEPKTKILL
                     NSKGGYGTSASEIKEDVIRQCVNVVKWEDCMRQMLTLENLTIAEVGVGKMMSSMIRGID
                     RSQK"
     CDS_motif       3116..3238
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg29_4_0002"
                     /evalue="8.20E-15"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ctg29_4"
                     /protein_end="119"
                     /protein_start="78"
                     /score="46.8"
                     /tool="antismash"
                     /translation="GVTPDVVAGHSLGQLSALHEAGVLSTYDLFRLVNKRAELMS"
     CDS             3780..4922
                     /locus_tag="ctg29_5"
                     /transl_table=11
                     /translation="MILRKGYSMSKSKVIVYDTNKQDMKSIIEDVFVNFPQDVKGKKVL
                     IKPNMLGPFEVERGVTTNPVLIEALVDYLIDCGANIIVGDNPGGQGGGVIAAAKKSGIY
                     QASKGHFENIGTACQLFPMNSRFVKEINVSDAVLDCDILIDLPRFKTHAYAGISGSIKN
                     MFGIVVGPGKAKLHFATPKPDDFHELLVDLYQVRVPDLVIMDGIYAMEGMGPTTGNLKK
                     IDKVLASTDGVALDATMARMMGFDIELIRHILVANERNLGVYKEEDIELVGDASKIEGF
                     ELPISYSAEVKATAPKMAGVLDLYKLSTTVPNFCKPENCVKCGECAKSCPVGAITMDPY
                     PVINRKKCISCYCCAELCLRECFEYIDGTQVFETLFSKLQ"
     CDS             4936..6036
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 102.9; E-value: 3.7e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_6"
                     /transl_table=11
                     /translation="MTIKEKYDAIVVGAGPAGAMCAFKLAKAGKEVLLVERAKMPRNKV
                     CTGMIAIDSIQIIEKEIGEFPKSLCVWPFNYKGFKYKMAKGAPVINMGIPEDEICYSVR
                     RSEYDHWLTLEASKKGATVVDNCAFISIQEKTKDSVTVRLLQTRYNGEKRFVTVKTDYL
                     IAADGMDSLLRKTLFPEREEITKCFCRQDYYLGDCDLDPEHYYYFRYNTAVEEPVWTFR
                     KDDSIVIGYVAYPANVLEEKRAKILDYFVNTHGLSIGELQFSEVCCESTNFTVKKMKNG
                     KLDFVFGCEDAPILFVGEAGEMMDSMSAGIAVAMESGCHAAEAIVAFGEKKEASLIDTY
                     KEISKDMIDHITGTWQAFYNRFGRFF"
     CDS             6052..7248
                     /locus_tag="ctg29_7"
                     /transl_table=11
                     /translation="MIFKMAVRNLGRNKRTNMVIGIIMAVGLIFVVIALSFIEGIKTNY
                     EQLILSTMAGDLSISAEDDTFAFTKDMENLTTNEQIRSVAPRLYASCYLFNADDDETYE
                     TVTAIGIDVDQDEALVDNFSRKEEEFVLGKDKIAITKQKAKALDLKVGDKAQLVFLTSK
                     GQSEKKEVTISCLYEGKSSNAAIEAWAILPISTMRSMLELEKDQVSTVKVFLEDGNDLE
                     EYRNLIEKKLDDKKYTVESWKETSAADMMRTPTIYSGILLAFAGVLFVLIAIGITSVLF
                     SALLGKTKEFGVMQTLGMKRGQIVLMNLFEMVILITVSMVSGVIICQLATIGINAAEIE
                     VASDALKFTFGGNVLSVKMTLVNCLIPAVFIFSLSCLISVIAVRKVTRIPILEAMNEQ"
     CDS             7260..7724
                     /locus_tag="ctg29_8"
                     /transl_table=11
                     /translation="MKNEIEIKVRFAETDAMGVVYHGNFYCWLEMGRYDLLEKYCENSK
                     REMAFGNYYLPVTKAECNYLDFVKFGDTIVVTTYLVRTDVPKLIFVSEIRKKGSKKLAA
                     RACTEHVFLNSEYKMLFKLPSFFKEDLEQIEREHPECLLTEKQRKERMKK"
     CDS             7721..9148
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222:dehydrogenase (Score: 195.6; E-value: 2.8e-59)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_9"
                     /transl_table=11
                     /translation="MSYDCIIIGGGMSGLVAATSLQAQGKKTLLIEKEARVGGYFSGFE
                     NEAGDRLDYAISYVLSCGEGDVVNEFLKKIGLDQKIKFHKLQNTDDIYMAGRHITFGEG
                     RENFKETLYREFPESKEQIDDLMNWLIDYQEGIAVQGSKAMQFFMQYFKKDYEDFLNTK
                     ITDETLKGLLALRIQADPASLMIMAGFVVECYFKGMYYPEGGSYHFVEQLVDFYKEKGG
                     EVITGEEICSFHCEEQKVVSVTSVSGKTYEAQNYIFNGDVINLNMKFLEGERKETTLKK
                     LSQRVVGHSSIDIYLTVKNYDLSKFQGGRVYLTKSEKVFDTYREVESGQIPKNPVIKLH
                     FPCHYDNTLTKDNRQIIRIETDICYDESKDTEEKYLKRASEIMQYVEETILPEISKHIS
                     YIRIITPVEFAKMFGHTHGSGTGWAHTTYNMMVSKYTQNTECSNLFIAGQWGEFGSGLR
                     QLVLSGEKAADMVRKRG"
     CDS             9151..10356
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (29-371). E-value:
                     2.6e-29. Score: 94.2. Matches aSDomain:
                     nrpspksdomains_ctg29_10_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: t2fas"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 175.1; E-value:
                     4e-53)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_10"
                     /sec_met_domain="t2fas (E-value: 7.2e-57, bitscore: 183.9,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKRLVITGLGFFSYQGFEKDTLWEEIEASNVEPQNYEKVEDKE
                     LGSFKAYEMAGHFDPNDYIENRKLKRLADFSKILCVASKNALTDAGISKDMEGYQPEKI
                     GSIVNTVHGPMNVTFDYLDDLLTTGPATARPILFQQTVNNVACGQVAIENQLKGVSSTI
                     IGASSLEYAANLLRKGTADAILVAGHEELHPYIFAAYASKNMLATDKGAGERSIPYAKE
                     ANGLVLGEGAGVLILETYESATRRNAHIYAELVDEIAVTDENYCKTYDEFKDNSTGFYR
                     AMNTVLSKNQVAPEQVDFISIAGNSYKATDATEQAAIERIFKDTSRMGYVASKAIFGET
                     LGASEVLAVISALLCMEHGKVPGLSYLEEKHSADKADCCIVNSLFTGGNINSVLLKKVQ
                     EA"
     aSDomain        9238..10263
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg29_10_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="2.60E-29"
                     /label="ctg29_10_PKS_KS.1"
                     /locus_tag="ctg29_10"
                     /protein_end="371"
                     /protein_start="29"
                     /score="94.2"
                     /tool="antismash"
                     /translation="ASNVEPQNYEKVEDKELGSFKAYEMAGHFDPNDYIENRKLKRLAD
                     FSKILCVASKNALTDAGISKDMEGYQPEKIGSIVNTVHGPMNVTFDYLDDLLTTGPATA
                     RPILFQQTVNNVACGQVAIENQLKGVSSTIIGASSLEYAANLLRKGTADAILVAGHEEL
                     HPYIFAAYASKNMLATDKGAGERSIPYAKEANGLVLGEGAGVLILETYESATRRNAHIY
                     AELVDEIAVTDENYCKTYDEFKDNSTGFYRAMNTVLSKNQVAPEQVDFISIAGNSYKAT
                     DATEQAAIERIFKDTSRMGYVASKAIFGETLGASEVLAVISALLCMEHGKVPGLSYLEE
                     KH"
     CDS             10358..11107
                     /NRPS_PKS="Domain: PKS_KR (6-175). E-value: 6.2e-21. Score:
                     67.0. Matches aSDomain: nrpspksdomains_ctg29_11_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     243; E-value: 5.6e-74)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_11"
                     /sec_met_domain="adh_short (E-value: 1.8e-42, bitscore:
                     136.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.2e-10,
                     bitscore: 31.9, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 7.3e-38, bitscore:
                     121.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSFKDKVVLVTGGSRGIGRAIVTEFVENDATVIINYNSSEEKALA
                     LKEELLAKNKAGKIYTVKANVSDPDRVKELFAHIKEEIGQLDILVNNAGITRDKFLVLM
                     NDTNWNDVIQTNLNSVYYCSKAALNLLAKNKRGTIINMSSTSALHPNAGQTNYAATKAA
                     IIAFTKALAKEVAKSGITVNAIAPGFIETEMTSLTNEKIKAAWMDSIPMKRFGAPEEIA
                     KTALFLASDGARYITGQHIVVDGGLTS"
     CDS_motif       10376..10456
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg29_11_0001"
                     /evalue="3.30E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg29_11"
                     /protein_end="33"
                     /protein_start="6"
                     /score="19.8"
                     /tool="antismash"
                     /translation="VVLVTGGSRGIGRAIVTEFVENDATVI"
     aSDomain        10376..10882
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg29_11_PKS_KR.1"
                     /evalue="6.20E-21"
                     /label="ctg29_11_PKS_KR.1"
                     /locus_tag="ctg29_11"
                     /protein_end="175"
                     /protein_start="6"
                     /score="67.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLVTGGSRGIGRAIVTEFVENDATVIINYNSSEEKALALKEELL
                     AKNKAGKIYTVKANVSDPDRVKELFAHIKEEIGQLDILVNNAGITRDKFLVLMNDTNWN
                     DVIQTNLNSVYYCSKAALNLLAKNKRGTIINMSSTSALHPNAGQTNYAATKAAIIAFTK
                     ALAKEV"
     CDS             11172..11447
                     /NRPS_PKS="Domain: PP-binding (8-86). E-value: 1e-10.
                     Score: 33.9. Matches aSDomain:
                     nrpspksdomains_ctg29_12_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_12"
                     /sec_met_domain="PP-binding (E-value: 5.4e-11, bitscore:
                     33.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEKVLQQEIKECIIDRLNLDVNPEDIDDDAPIFSGEDGEAVEGS
                     LALDSVDALEIVVALNNQYDIEITDNDMMIFQSVNTIAQFVEEKRG"
     aSDomain        11196..11429
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg29_12_PP-binding.1"
                     /evalue="1.00E-10"
                     /label="ctg29_12_PP-binding.1"
                     /locus_tag="ctg29_12"
                     /protein_end="86"
                     /protein_start="8"
                     /score="33.9"
                     /tool="antismash"
                     /translation="EIKECIIDRLNLDVNPEDIDDDAPIFSGEDGEAVEGSLALDSVDA
                     LEIVVALNNQYDIEITDNDMMIFQSVNTIAQFV"
     CDS             11454..12674
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (78-402). E-value:
                     5.7e-49. Score: 159.0. Matches aSDomain:
                     nrpspksdomains_ctg29_13_PKS_KS.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     HR-T2PKS: hr-t2pks-ksa"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022:Beta-ketoacyl synthase (Score: 322.6; E-value:
                     6.9e-98)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg29_13"
                     /sec_met_domain="hr-t2pks-ksa (E-value: 8.8e-112, bitscore:
                     364.8, seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRVVITGIGVISSIGTGKEDFMEGILSGKDGKKDIPYFNTEKYT
                     LKRANIVEGFHETQYCMKNGNTEKEAANVYGLYASKQAMEDAGLISASYANDRKGVAVA
                     TSLGSIGGKANIHQQILDGKSYQDVDFSAAFECCSTPSGVISKEFECYGPNISVSTACA
                     AGTNSIGCGYDMIKNDTCDMVIAGGSDPFEQMSFSGFLSLKTITQNELTPFDLNRSGID
                     IGEGAAVVILEELDSALKRGANIYAEVLGYGLSNDAYHATSPDPNGGGARLAMSMAMKE
                     AGINLQDVNYINAHGTGTKINDKMETGAIAELFGHHASDIMISSTKSMHGHMLGATGSI
                     EAIVCALAIKEGFVPATTKTKELMEECENLDIVLGTFRKEQIQYAVSNSFGFAGNSSSI
                     VIGRYVC"
     aSDomain        11688..12659
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg29_13_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="5.70E-49"
                     /label="ctg29_13_PKS_KS.1"
                     /locus_tag="ctg29_13"
                     /protein_end="402"
                     /protein_start="78"
                     /score="159.0"
                     /tool="antismash"
                     /translation="ASKQAMEDAGLISASYANDRKGVAVATSLGSIGGKANIHQQILDG
                     KSYQDVDFSAAFECCSTPSGVISKEFECYGPNISVSTACAAGTNSIGCGYDMIKNDTCD
                     MVIAGGSDPFEQMSFSGFLSLKTITQNELTPFDLNRSGIDIGEGAAVVILEELDSALKR
                     GANIYAEVLGYGLSNDAYHATSPDPNGGGARLAMSMAMKEAGINLQDVNYINAHGTGTK
                     INDKMETGAIAELFGHHASDIMISSTKSMHGHMLGATGSIEAIVCALAIKEGFVPATTK
                     TKELMEECENLDIVLGTFRKEQIQYAVSNSFGFAGNSSSIVIG"
     CDS_motif       12324..12371
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg29_13_0001"
                     /evalue="2.00E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="ctg29_13"
                     /protein_end="306"
                     /protein_start="290"
                     /score="10.8"
                     /tool="antismash"
                     /translation="YINAHGTGTKINDKME"
     CDS             12668..13564
                     /locus_tag="ctg29_14"
                     /transl_table=11
                     /translation="MLIPFKKADCQMVTIMQSVMKFFQYEAPSETYYLMGNARMLTLAF
                     LDDHVSLFRQGFAYVNDVCYFSGAWDSDFLTLDADGFIEKLNEKWHEWADMQQPMPIIV
                     GLVDSDKISPAFYVLVGYNKENAFYELLTATGEQVLMSETQMKRDHNRYGFATIDVPYN
                     FLVKSQYYRTVEGAGVGILQKAGLTLSQHLKMTQVLEKLDRNAKEENLEALQEELQLLG
                     TRFLGGDVSKSLNRIEYGEALRMAGYESMGEQYQILGQYWEQLLTSQMEQHIVNIPLLR
                     SILDMERQLIKEQKESV"
     CDS             13564..14601
                     /locus_tag="ctg29_15"
                     /transl_table=11
                     /translation="MRVLLDLEQYHRMGSHCLTTCLVTLFRQQGIGMPEEMSLGLGSGL
                     GFTYVRQKGGFMYGGRGGNLEQNLASSLGLELVANRTQDKDIAWEYNRQMLLGCHPLIC
                     EVDMAHLPYMVEKLKTNGSGFSGHKLILIGFDDEKNETYVLDYLWNDVVVVNTDDFKKA
                     ASSSIKPMSPDNSSLWMQIPKELYPMEYAIHSAIGVNVNQMKNPVGFGLGLKAIKRFYK
                     ELRSWPDILQEDTLRYELNMAHLVFEKVGTGGGNFRRMYARFLKNSATLLQNEQLLEAS
                     KTYTELGKLWKTVAYDLHEASVEEKLLDHKIFSRNYETGEQIMKLENQGIQQLERYLEG
                     GRTCY"
     CDS             14592..15011
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1270:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine
                     (Score: 105.9; E-value: 4e-32)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_16"
                     /transl_table=11
                     /translation="MLLIDEIYKSLPHRFPFLMVDRIVSVEKEKSVIGLKNVTVNEPYF
                     QGHFPDEPLMPAVMIIEAMSQVGGFIFDLDNERGYVIGVDKAKFKRKVIPGDQLIIECE
                     KIAHVGTMAKVKGVAKVDGKVVASAEIAYNFAKIS"
     CDS             15025..15729
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 227.9; E-value:
                     2.1e-69)"
                     /gene_kind="transport"
                     /locus_tag="ctg29_17"
                     /transl_table=11
                     /translation="MIQIKALNKVYGTGKVQFQALKNVDITIKEGEFVVLAGPSGSGKS
                     TLLNIIGGMDTATSGSVLVNGQDIVKLNKRQLTQYRKSQLGFIFQKFNLIDTLTVFENV
                     EFTLMLKKWKKAERRALVMDMLKNVGLDTKEKNFPKNLSGGQQQRVAIARALVGNPVVI
                     LADEPTANLDSKNGKECIEMLHRLNKEKNVTIILTTHDQRIIDTSDNVIYLVDGQIDQV
                     RTSHKNKGENAS"
     CDS             15726..16787
                     /locus_tag="ctg29_18"
                     /transl_table=11
                     /translation="MKMIEGFKVKIGTLCISSVLRDITNHMLGVNYGEEIYYGLGCGLF
                     FAYTMSNEVVGLGGFTDLILDNLRDSLTLTKVETYAPDDVVFDKIRFSIDAGLPVLVSG
                     LHFHSKEDLALDTEATEKLDLPMNYHYTIIAGYDDETKELFMADNKSSGNVSYENFLKF
                     RDHRNMLTQFLFPPTLEHLDARIYAAIRKLTDYWYRMPENPKSFADVYTTDFLHLSNVY
                     NTMEGLENFRKLFLHGPEMESLENFQKSMFFIQAISYRGTGGDMTRGLYSRFLREGGAI
                     TGEDKMLEVSKLYATAAREWRKFFKIFDGNPTVIYEQIKDETQNSVFFEAIEQVYQCEM
                     TAMSALNDLAYGK"
     CDS             16765..17181
                     /locus_tag="ctg29_19"
                     /transl_table=11
                     /translation="MIWHMENKKLEMKQKYPMEMNLGVLRDIQENSCVFDVEFSRNDFM
                     GQKPLWMPASCFMELLGQAAEYLMRSTQGDCKRYLVQVNEFTLDPEFYQVMDQNFTLRV
                     ELTQTFGNLNKSRASLSHGERSYCEGSFMHSDIT"
     CDS             17205..18836
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg29_20"
                     /sec_met_domain="PIG-L (E-value: 7.3e-22, bitscore: 69.5,
                     seeds: 137, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_2 (E-value: 9.5e-27,
                     bitscore: 84.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGFVKIRLQSLLNKTAISTLTEATFSQGGNVLILSPHYDDDVIS
                     CFGAMTKHYEQGAHLDILYLTDGTTSKDSGLTKEELHKIRKVEAANAVNTFFKDVNLEH
                     FNHEDGHFAMTLEDVTRLSKLLQEKQYDYIYCPSITDTHEDHKETYKLLRQALLESGLK
                     CTIRLYEFWYPLKKPNVYVDFADCEEKKWESIACHQSQMKYLNYVELAQTVNAHRGLQA
                     ERKWCEVYEEMSSAKLIWDLVPSLKASVVIPAYNNEAYVAIMLKALQRQTLDTFCWEIV
                     LVDDSEDNRMTQFEKWELPNLRVIEKEHSGRADARNVGIQNSRGEVIIFMDSDMIVEES
                     FVEKHYASHRETGSDITLGKVNHICHEHLEEVRKLVLEDRTKELEAFVMKDEYLNLTPI
                     VFQNKEAADNIGWVCCLFSNCSVRRKVLDKAGVFDVIFKGWGLEDIELGYRFFKEKFSF
                     SYEEDIANYHVDHATNSQQMLVEMGRNLKRLSKKHPDAAIKSYMSFVAGFKDLQELLCD
                     VAKKEIAFDNGSGVYFRPISYTKSKA"
     CDS             18856..20067
                     /locus_tag="ctg29_21"
                     /transl_table=11
                     /translation="MITLKLAVRTITMKFSRYVLLCIVFFVSTIALIFNFIGAHAIKNS
                     MEGACIRIFTGNVMVKNVEYDYRLGLASSGDPKLVEHVADYIEAYEKEEGVTGCVARVR
                     RGVQVTSEKTEYMNLIGVDTDREVKYSEFKVREGKVTMKSGEAIISKTCLDRMDLTIGD
                     NVYINMVSAQGIPMRKEYEIVGVIDNTNMNFLRQDEIYIPYQDALDLLQMEDVATELLV
                     YTKDKTPSDEQLTTFNKIAKDKDIKAYPWVEIGNEIIYASLGAYAAILFLAIACAVIIC
                     ALVYNLTSMSIYSQIRMIGTMLALGMTHGKVLVKFICENLLVGLLSCGLSAVLAILGIQ
                     AMSSRQIPLGVAAEIFGNDYLTLHIDYRVIFLVALSVAFFSIISTLIAFCKIRSIQPIE
                     AIIQ"
     CDS             20099..21037
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 195.4; E-value:
                     1.9e-59)"
                     /gene_kind="transport"
                     /locus_tag="ctg29_22"
                     /transl_table=11
                     /translation="MGNIVVVEALVKKYGQFTAVNHMNLEVKEGSIYGFLGPNGAGKST
                     TLSIIATLLRMNEGHVTIDGLDLEKQKSKIRQLIGWVPQEIVLYPRMSIRENIRFYGSL
                     YGLHGAKLEQACEEALKVVSLDQDTGRKVMGLSGGMQRRLNIACGIVHHPKLIIMDEPT
                     VGVDAQSRDLIMDSIKSLNQAGSSIIYTSHYMHEVEELCDEIGIVNKGQMIARGTYEEL
                     ATEYADGNCFCVDTSKEALQFHMQEIMGKYVDLHVSVDENTLKFLVQGENHINRILQDM
                     ISMNMPVYRLTSEQMSLEDIFLRLTGKQTAQ"
     CDS             21053..21844
                     /locus_tag="ctg29_23"
                     /transl_table=11
                     /translation="MIILYEIKKFFKEIPNLVFLLALPIIMLYVLGKTSAGFTTVVLEN
                     MQEFPAQYELMNLKEVMIPSCYGVMDYFGITMLMMMSFLTCILGANSYSEEYRQKTINR
                     LLVAKHSRFRIFIEKTVGLLLVAAFEIGVFLVIAKGIYKVSFATVRREEVAILLLAFVN
                     SILMLFLGNVIGMIFRKNTLMIIMPLFCIMMLFGGTFTGNLYIEGLSDWMPIYQLQMAA
                     FRVGTLHTYDLFKTVLYIEGTASILMAGVAFWLFLRQDEVR"
     CDS             21864..22865
                     /locus_tag="ctg29_24"
                     /transl_table=11
                     /translation="MLLKTESIKWVFLLSCMFSVILCIVFSITYKANLKKDDRSITISV
                     WDESKSQESEKLLSYMENTLDAKILLGDQKQMENQLITFRAMVGVKIPEGFAQGELPQV
                     IHFEDDKIAQMVSSLIDQYVWLQDDVTPKKVDVEARKENAVAKALKTTMGFLPQALMIM
                     AICLSIFLVTEKQEGNLMRIYISPVSFLQYMLGRGGLSVLVSLIPAFALWGMVAFYLGY
                     DDISVMQAFENMVLFTIFMMLTAFYLGLRCTTQNTIFLGIVGLTSVGSIIGGCFFSIDG
                     TVKVLETIAKVLPHYWLMKVGQGQFLLIYIVIMIVLNFVTYEKLNKNGGKIG"
     CDS             22862..23581
                     /locus_tag="ctg29_25"
                     /transl_table=11
                     /translation="MILEGANFKIVNISGSPHGGIGNTQFLVKTFAQRLEEKGANVELV
                     NHYVVKEHVEECRGCTRCMRKGECVMSEKDDVKDMVQDLLSADLVVFSSPIYVLNVTSL
                     MKKFFDRTAYMTHRIVLENKLGFYVLSSQGLGIDTVSAYMQSVMEAMGVTVLGSIKGTA
                     IFHNQFLNQEEIDQSIDEILTSLEQDFYKETQLYSESEKKRREKFSSLMDQEEISKKLF
                     HEDYKYWANKKETSEIL"
     CDS             23754..23924
                     /locus_tag="ctg29_26"
                     /transl_table=11
                     /translation="MTNPEIADVIYIEPLNVDRLEQIIANERPDAVLPNLGGQSGLNLC
                     SELSQKGILGY"
     CDS             complement(24077..24313)
                     /locus_tag="ctg29_27"
                     /transl_table=11
                     /translation="MLKQMSRIPLKNPKTFDNYDFSRINGKNVDTLKELSTLSSLYAHK
                     NIAFIGPQGVGKTHLVMASGRICCDNEYNAYFL"
     CDS             24373..24627
                     /locus_tag="ctg29_28"
                     /transl_table=11
                     /translation="MIVLQCICFFSIMFAKFAIEEILPIVIANAACGMNLEFPRKLYVL
                     TFATILGLYIIIEYHCSDCKLSASILWHNYSPQFKYIKD"
     CDS             24664..25206
                     /locus_tag="ctg29_29"
                     /transl_table=11
                     /translation="MKCKKIINTKKMVLSALLLALGMILPMLTMQIPTIGNMLLPMHIP
                     VLLCGFICGAPYGAMIGFALPIIKSIVFGTPILMPNALAMSFELLCYGFFSGFFYCLLK
                     KRKGQIYVSLILTMFIGRVAWGCATYILYYILGNRLTWKIFLTQAFINSILGIIIQLMI
                     VPYITRIVKIYIGENDC"
     CDS             25206..25811
                     /locus_tag="ctg29_30"
                     /transl_table=11
                     /translation="MNEIVIQKMCKKSFEPVVKRIDQLLKEKDEYILVAIDGKCAAGKT
                     TLAYYLKELYKCNVFHMDDFFLQMQQRTVERFNEVGGNIDYERFKEEVLKFIIQKKDVI
                     YRPFSCKTLNFQEAKIMEFHRLNIIEGSYSQHPYFGNVYHLRVFLDIPEDLQIARIRFR
                     NGERMLERFKNEWIPKENEFFLKYDIRRQSLIINGARI"
ORIGIN
        1 ttagacgagc ttcgtaaaat gggacctttt ccaaagccgg atgatctaaa tcggcttttg
       61 ccatggtcaa atgaattacc ggaaggattt cgaaccaaaa agaagaaata aaatgtgccg
      121 ccctgatggg cggcatgttt tttaaaaagg caaggtacag atgattacgt acttacttta
      181 taggatgaaa catgtttgta gagtttggac ataaaatgtc gaaatatgga cattggattt
      241 aaatattttg gaaatcggtg tatgatgcta aaaaaaagga ggataaactc atggaagtta
      301 aaaatttttt gggaaaaggt gtaatgaaat gtttaaatgt cttagcgtta ttgttggtta
      361 tgcagactgc gaactcggca tgtatatggg tggctcacca acctgaattt ccagaagcgg
      421 ctaataagtt taagtttaat aagtaatttg taaaatggac gtcataatac gacattatat
      481 ttactttgtt aaggtaaatc gacatataat atatattttt tgttaaatat agacaaactg
      541 atgatgtgct ttttgataaa aactgaaata tgagtcgata taatgtcgta caatatttac
      601 ttgtatagaa aggtaggaga agattgacaa aaggacgaat ttgtaaagcc tgtaaacggg
      661 aaatacaaag agatatttta gacgctaatt tgtcggtttg tccgttctgt ggatattata
      721 tgagatttca tgcaaagaaa cgtattgtgt ctttggctga taaaaattcc tttcgtgaat
      781 gggatgttaa tacaaaatgg agcaatccgc ttaatgatga tatgtatgct cgaaaattgg
      841 tcactacagc tgataaacat aagctagatg atgccattat tacaggagaa attaatatta
      901 atggagaaca tcttgctatt ggtgtgatgg atagtagatt tatgatggcc agtatgggtc
      961 atattgtggg agagcgtgta accagtttgt ttgagagagc tacgaagaaa aaattgcctg
     1021 tgattttgtt ctgctgttca ggtggagcaa gaatgcagga gggtataatc tcgttaatgc
     1081 agatggagaa gactgcagca gcagtaaagc tccatagcga tgcaggtgga ctatatattt
     1141 ccgtcctgac caaccctact atgggaggtg tcactgcaag ctttgccaca ttggcagata
     1201 ttgtgttggc agagaaaggt gcaatgattg gatttgcggg agccagagtc attgagcaga
     1261 acacaggaaa gaaattacca aatggcttcc agacagcaga gttccaaaag gaacatggat
     1321 ttgtggatat gatcatagaa agagcggatc ttcgagatac cttgtcctac ttcctaaaac
     1381 ttcatcagaa aaaagcaagt ctgcattcag gtgagaaaaa agtacctgaa gtgtatgtga
     1441 acaaaaggtt agcacagaag actgcttggg aaagagttat gatcgcaaga tccatgaacc
     1501 gccccaccag taaggattat atcgatcagc tattccaaaa gttcacagaa ctaagtggag
     1561 acagaatcag cagtgatgat tgcgctatcg taggaggcgt tgcctatttc cgtggttgtc
     1621 cagtgacagt catcggacat cagaagggaa aaggttccgt cgaagcagca ctgtatcgaa
     1681 actggggaat gcctttacca caaggttata gaaaagttat gagacttgca aaacaggcag
     1741 agaagttcca ccgaccgatc atcttcttca ttgataccat tggcgcagcc tgtggtcagg
     1801 aagcagagga aaggggccag ggcgtggtca tcgccaatgt acttcaggaa atgagcaccc
     1861 tgaaagtacc tattctttcc atcgtcatcg gagaaggcgg aagcggtgga gctcttgcat
     1921 taggggtagg taatgaagtg tggatgttag agaatgcggt ttactccgtt ctgacaccag
     1981 aaagttatgc aagtattttg tggaaagata gttcaaaagc ccaacaggcg gccatgcaga
     2041 tgaagctgga agcaagcgat ttgtacgagc ttggaattat tgacaagatt atttacgaag
     2101 aagagccagt gaccagggat aacatggaga tggtatgcag ggaactggaa aatgagatga
     2161 ttacgtttct gatgaagtat ctaaagaaga ctcctgcagg agtagcaaaa gaacgttatc
     2221 ggaaatttag gaaatattaa aatgataacc gtttattatt ttgatattga gaagcataga
     2281 caaatgctaa ggcatgaatc catgttgcgt gaaaagggaa aagatcagaa ggtacttcgg
     2341 gaaaaaaaac agttagagat gatcgcatcc gagtatctga agagatatgt atttgaggaa
     2401 gtattacata aaaattatcc agaggagctt tttaggggag agttcgggaa accatattgt
     2461 agagatcaat tctgttgctt taacgtaagc ggacagaaag atttcatcgt tcttggactg
     2521 acgcaaaaag attccattgg aattgatatt gagaagaagc gtgaattacc agggactgcc
     2581 gtagggagtt ttttttatgg caatgagtgg gataccatct tgaatgaccc aaaagaattc
     2641 acaagaatct ggacccggaa ggaagcattt gtcaaatgca ttggaactgg ttggaaacat
     2701 aaacctgaca tatgtgttgt tgatgatcag atcagtttcg atggtaagaa gtatcagata
     2761 gcatcatggg aatttcatga tgactatgtg atcagtgtgt gttatgagga tgcaggatat
     2821 aagcatcagt atgagatggt agaagttatt tagttgatga ggagaggctg gtaggagtat
     2881 catgatcgca tttttattcc caggccaggg aagtcagaga gcaggcatgt atgaactgct
     2941 tggcgacaag gcaaacgaga cagatgaatt atttgatatt gcaaaagagg cgacaggaag
     3001 agacgttctt agtctttgta aagatgctac agatgaggag ttaaagcaga cttacaatac
     3061 ccagcttagt gttacagcca tgaaccttgc ttttgcaacc ttgttaaagc acagaggtgt
     3121 cacgccggat gtggttgcag gtcatagctt gggacagtta tctgcattac atgaagcagg
     3181 ggttctgtcc acttacgatc tgttccgcct ggtgaacaag agagcagagc ttatgagcgg
     3241 tttgaaggag tcgggaaagc ttgcgacgat tcttggctta gagaaaaatg ttgtggaagc
     3301 ggtttgcgag gaaacatgtc aaacaactga ccaggtacgt attgctttgg agaattccta
     3361 caagcagtac gtgatcggtg gaagagaagc agatgtggac gtggcagtag cgaaaatgaa
     3421 agaagctgga gctcttaaga ttgtggagat cagagtcagc aatgcgttcc acacttacat
     3481 gatggagcct atggtggaac ctttcaaaga atttatcaat acactggatt tccaagagcc
     3541 aaagacaaag attcttttaa actccaaagg cggatatgga acaagtgcca gcgagattaa
     3601 ggaggatgtc atcagacagt gtgtcaatgt agtgaaatgg gaagactgca tgagacagat
     3661 gctgacatta gagaatctga ccattgctga ggtaggtgtt ggcaaaatga tgtccagcat
     3721 gattcgtggt attgaccgta gccagaaagt atacctgaca agcaatacca atgacttcaa
     3781 tgatcttgcg aaaggggtat agcatgagca aatcaaaagt aatcgtatac gatacaaata
     3841 aacaggacat gaaatccatt attgaggatg tgttcgtaaa ctttccacag gatgtgaaag
     3901 gcaagaaagt attaatcaag cctaacatgt taggaccgtt cgaagtggag agaggtgtta
     3961 ccaccaatcc ggttttaatc gaagctttgg tggattactt gatagattgt ggcgccaata
     4021 tcattgttgg agataaccct ggtggacagg gcggtggagt aatcgctgct gcaaagaaga
     4081 gcggtatcta ccaggccagc aaaggacatt ttgaaaatat aggtacagct tgtcagttgt
     4141 tcccaatgaa ttccagattc gtgaaggaga ttaacgtgtc tgatgcagtt cttgactgtg
     4201 atattttaat cgatcttcca agattcaaga cacatgcata tgcaggaatc tctggatcca
     4261 ttaaaaacat gtttggtatc gttgtgggac caggaaaagc gaagttacat tttgcaactc
     4321 ctaagccaga cgatttccac gagcttttag tagacctgta tcaggtaaga gttccagatc
     4381 tggtaattat ggatggtatt tacgccatgg aaggaatggg accaactaca ggtaacctga
     4441 agaagattga taaagtgctg gctagtaccg atggtgttgc actggatgct accatggcca
     4501 gaatgatggg atttgatatt gaactgatcc gtcacatttt ggtagctaat gagagaaatc
     4561 ttggagtata caaggaggaa gacatcgaac ttgtaggtga tgcttccaag atcgaaggat
     4621 ttgaacttcc tatctcttac agtgctgagg taaaagctac ggctcctaag atggctggtg
     4681 ttcttgatct gtataagctt agcaccaccg ttccaaactt ctgtaaacct gagaactgtg
     4741 tcaagtgcgg tgaatgtgca aaatcctgtc cagtaggagc tatcaccatg gatccatatc
     4801 cagtgatcaa cagaaagaaa tgtatctcct gctattgttg tgcagagctt tgcttaagag
     4861 agtgcttcga atatatcgat ggaacacaag tttttgagac attgttctca aagcttcagt
     4921 aagtaggagg taatcatgac gattaaggaa aagtatgacg cgattgtcgt tggagctggt
     4981 cctgcaggag ccatgtgtgc attcaaactg gcgaaagctg gaaaagaggt acttctggta
     5041 gaacgtgcca agatgcctcg taacaaagta tgtactggta tgattgccat tgacagtata
     5101 cagattattg aaaaagagat tggagaattt ccaaagagcc tttgcgtatg gccatttaac
     5161 tataaaggct ttaagtacaa gatggcgaag ggtgctccag tcatcaacat gggaattccc
     5221 gaagatgaga tctgctacag tgtaagacga agtgaatatg accactggct gactttggaa
     5281 gccagcaaga agggcgctac agtcgttgat aactgtgcat tcatcagtat tcaggagaag
     5341 acgaaagatt cagtgacagt cagacttctg caaactagat acaatggtga gaagagattt
     5401 gtcactgtga agacagatta cctgatcgca gcagatggta tggatagttt acttagaaaa
     5461 actctttttc cagaaagaga agagattacc aaatgttttt gcagacagga ttattacctg
     5521 ggcgattgtg atctggatcc agaacactat tactacttcc gatacaacac ggctgtagag
     5581 gagccagtat ggactttcag aaaagatgac agtattgtca ttggttatgt ggcttatcca
     5641 gccaatgtct tagaagagaa gagagctaag attctggact attttgttaa tactcatggc
     5701 ctttccatcg gagagttaca gttctctgag gtgtgctgtg aaagcaccaa cttcactgtg
     5761 aagaagatga agaatggtaa gcttgatttt gtgtttggat gtgaagatgc accaattctg
     5821 tttgtcggtg aggcagggga aatgatggat tccatgagcg ctggaattgc agtagccatg
     5881 gaaagtggat gtcacgcagc ggaagcaatc gtagctttcg gggagaagaa agaagcttct
     5941 ctgatagata cttacaaaga gatctccaag gatatgatcg atcatatcac aggaacctgg
     6001 caggcattct ataacagatt tggaagattc ttctaaaggg gaggaaaaag agtgattttt
     6061 aaaatggcag tgcgtaactt agggagaaat aaaagaacta acatggtgat cggaatcatc
     6121 atggcggtgg gactcatttt cgtagtcatc gcacttagct ttatcgaggg aataaagacg
     6181 aattatgaac agctgatttt aagcactatg gcaggagact taagcatctc cgcagaagat
     6241 gacacctttg catttacaaa ggatatggag aatctgacaa ccaacgagca aataagaagt
     6301 gtagcaccta gattatatgc cagctgctat ctgtttaacg ctgacgacga tgagacatac
     6361 gagacagtga cagccatagg gattgatgtg gatcaggatg aagctcttgt agacaatttt
     6421 tccagaaaag aagaagagtt cgtgttagga aaagataaaa tcgccatcac aaaacagaag
     6481 gcgaaggccc tggaccttaa ggtgggagac aaggcacagc tggtattctt aacaagtaaa
     6541 ggccagtccg agaaaaaaga ggtgaccatc tcctgcctct atgaaggcaa atccagcaat
     6601 gcagccattg aagcctgggc gattcttccc atatctacca tgcgctctat gttggagctg
     6661 gagaaagatc aggtctctac ggtgaaagta ttcttagagg atggaaacga cctggaagaa
     6721 tataggaatc tgatagaaaa gaaactggat gataagaaat atactgtgga aagctggaaa
     6781 gaaaccagcg ccgcagacat gatgagaact ccaaccatct attcaggaat tcttcttgca
     6841 tttgcagggg tactcttcgt actgatagca atcggtatca ccagtgtttt gttctcagca
     6901 ctgcttggca agaccaagga gttcggagtg atgcagacct taggaatgaa acgaggacag
     6961 atcgtactta tgaatctttt tgagatggtg attctgatca cagtatccat ggtatcgggc
     7021 gtcatcattt gccaattggc cacgatcgga atcaatgctg ctgagattga agtggcaagt
     7081 gatgcattga agttcacatt cggaggtaac gtgctcagcg tcaagatgac attagtgaat
     7141 tgcctgattc cagctgtatt cattttctct ttgagctgtc tgatttcagt cattgcagtg
     7201 agaaaagtta caaggattcc gattctggaa gccatgaatg agcagtaagg agaagaactg
     7261 tgaagaatga aatagagatt aaggttagat ttgctgagac agatgccatg ggtgttgtat
     7321 atcatggtaa cttctactgc tggctggaga tgggaagata tgacttgttg gaaaaatatt
     7381 gcgagaacag caagagagaa atggcttttg gcaattatta tcttccagtg accaaagcag
     7441 aatgcaatta tctggacttt gtaaagtttg gcgacaccat tgtggtgact acttatcttg
     7501 tgagaacaga tgtgccaaaa ctgatctttg tgtcggaaat ccgcaagaaa ggttccaaga
     7561 agctggctgc aagagcctgc acggaacatg tttttctgaa cagcgaatac aagatgctgt
     7621 ttaagcttcc gtccttcttc aaagaggatt tggaacagat tgaaagagaa catccagaat
     7681 gtcttttgac agaaaaacag agaaaagaga ggatgaaaaa atgagttacg attgcatcat
     7741 catcggtggt ggcatgtcag gactggtagc tgcaacaagc ttacaggcac aaggcaagaa
     7801 gacactgctg attgagaaag aagcaagagt gggcggctat ttttcaggct tcgaaaatga
     7861 agccggggac agattagact atgccatctc ctatgtttta tcctgtggag aaggagatgt
     7921 ggtcaacgag ttcctgaaaa aaataggatt ggatcagaag ataaagttcc acaagcttca
     7981 gaatacagat gacatttata tggctggaag acatattact ttcggcgaag gaagagagaa
     8041 cttcaaggag actttataca gagaattccc tgagagcaaa gagcagattg atgatcttat
     8101 gaactggctg atcgattacc aggaaggaat cgcagttcag ggaagcaagg cgatgcagtt
     8161 ctttatgcag tatttcaaaa aggattatga agactttttg aacacaaaaa tcaccgatga
     8221 aactctgaag ggacttctgg cacttcgcat tcaggcagat ccagcatccc tgatgattat
     8281 ggcaggattt gtggtggagt gttacttcaa aggtatgtat tatcctgaag gaggttctta
     8341 tcacttcgta gaacagttgg tagacttcta caaggaaaaa ggcggagaag tgattaccgg
     8401 agaagaaatc tgctccttcc actgtgaaga gcagaaggtt gtttctgtga catcagtgtc
     8461 aggaaaaact tatgaagcgc aaaattacat cttcaacggc gatgtcatca acctgaatat
     8521 gaagttctta gagggagaga gaaaagaaac tacactgaaa aaactttccc agagagtggt
     8581 aggacattct tccatagaca tttacctgac agtaaagaat tacgacttaa gtaagttcca
     8641 gggtggaaga gtctatctga ctaagagcga gaaagtcttt gacacctatc gagaagtgga
     8701 gtcaggacag attccaaaga atcctgtcat caagttgcat ttcccttgcc actatgacaa
     8761 tacactgacc aaagacaatc gtcagatcat cagaatcgaa acggatattt gctatgacga
     8821 gagcaaggat acagaagaaa aatatctgaa gagggcttct gagatcatgc agtatgtgga
     8881 agaaaccatt cttccggaga tatcaaagca catcagctac atccgaatca ttactcctgt
     8941 agagtttgct aagatgtttg gacataccca tggttcaggt accggttggg ctcataccac
     9001 ctacaatatg atggtttcaa aatataccca gaatacagaa tgtagcaacc tattcattgc
     9061 agggcagtgg ggcgagttcg gttccggact aagacagctg gttctgtcag gagagaaagc
     9121 tgctgacatg gttagaaaga gaggataagt atggacaaga agagattggt gatcacggga
     9181 ttaggtttct tctcttatca gggatttgaa aaggacactc tttgggaaga gattgaggct
     9241 tccaacgtgg aaccacagaa ttacgaaaaa gtagaagata aggaattagg ttcttttaag
     9301 gcttatgaaa tggcaggcca ttttgatcct aatgattata ttgagaacag aaagctgaag
     9361 agacttgctg atttctccaa gattctatgc gtagcatcta agaatgcttt gacagatgca
     9421 ggaatttcaa aggatatgga aggatatcag ccagagaaga ttggttctat cgtaaataca
     9481 gtacatggac ctatgaatgt tactttcgat tatctggatg atcttctgac cacaggacct
     9541 gcgacagcaa gaccaatcct gttccaacag acagtaaaca atgtagcttg tggacaggta
     9601 gccatcgaga atcagttaaa gggtgtcagt tcaacgatca ttggagcttc gtctttggaa
     9661 tatgcagcga accttttaag aaagggaact gcagatgcta tcctggtagc aggacatgag
     9721 gagttacatc catatatctt tgccgcatat gcttccaaga atatgttagc tactgacaag
     9781 ggagctggag agcgttccat cccttatgcg aaggaggcca acggtctggt actgggagaa
     9841 ggagcaggtg ttttgattct tgagacttac gaaagtgcca cgagaagaaa tgctcatatc
     9901 tatgcagaac tggtagatga gattgctgtg acagatgaga actactgcaa gacttatgat
     9961 gagttcaagg ataattccac aggcttctac agagctatga acacagtact ttctaagaat
    10021 caggtagctc cagaacaggt agactttatc agtattgcag gtaattctta caaggccaca
    10081 gatgcaacag aacaggcagc tatcgaaaga atcttcaaag ataccagtcg tatgggttat
    10141 gtagccagca aagcaatctt tggtgagact ttaggagcca gcgaagtatt agcagtgatc
    10201 agtgctcttc tgtgtatgga acacggcaag gtgccaggtc tttcttactt ggaggagaag
    10261 cacagtgctg acaaggcaga ctgctgtatc gttaactcac tattcacagg tggcaatatc
    10321 aactctgtgt tgttgaagaa agtacaggag gcataagatg tcatttaaag ataaagtcgt
    10381 gttagttact ggtggctcaa gaggcattgg acgggctatc gttacagaat ttgtagaaaa
    10441 tgacgccact gtcattatta attataacag cagtgaagag aaggctcttg cattgaaaga
    10501 ggaactctta gcaaagaata aggcaggtaa gatttacacg gtgaaggcca atgtcagtga
    10561 cccagatcgg gtaaaagaac tgtttgccca catcaaagag gagattggac agttagatat
    10621 cctggtaaac aatgctggaa tcaccagaga caagtttctg gtgttaatga atgataccaa
    10681 ctggaacgat gtcattcaga ctaatttaaa ctccgtatat tactgctcta aagcagcttt
    10741 aaatcttctg gcgaagaata agcgcggtac catcatcaat atgtcaagta ccagtgcact
    10801 gcatccaaat gcaggacaga ccaactatgc agctaccaag gcagccatca ttgctttcac
    10861 aaaagctttg gcaaaggaag tggctaagag tgggattact gtcaatgcca ttgcccctgg
    10921 tttcatcgag acagagatga catcacttac caacgagaag attaaggcag catggatgga
    10981 cagcatccca atgaagcgct tcggagcacc agaagagatt gcaaagacag cactgtttct
    11041 ggcaagcgac ggcgcaagat acattacagg ccagcacatt gtagtggatg gcggattaac
    11101 cagttaataa tagaatcatc catggatgtt ctattcaaat aataaattac aacctaaagg
    11161 agaaaacaaa aatgagcgaa aaagtattac agcaggaaat caaagagtgt attattgaca
    11221 gacttaactt agatgtaaat ccagaagaca tcgacgacga tgctccaatc ttcagtggtg
    11281 aggacggaga agcagtagaa ggatctttag cattggattc tgttgacgca ttagagatcg
    11341 tagttgcttt aaataaccag tatgatatcg agattacaga taacgatatg atgatcttcc
    11401 agtctgtaaa tacaattgca cagttcgtag aagaaaaaag aggttaatta gttatgagaa
    11461 gggttgttat tactggaata ggagtgattt cctcaattgg aaccggcaaa gaagatttca
    11521 tggagggtat attatctggt aaggatggaa aaaaggatat tccatatttt aatacagaaa
    11581 aatacacctt aaagagagca aatatcgtag aaggttttca tgaaactcaa tattgcatga
    11641 agaatggcaa tacagaaaaa gaagctgcaa atgtctatgg cttatatgcc agcaaacagg
    11701 caatggaaga tgcaggactt atcagtgctt cctatgccaa tgacagaaaa ggagtagcag
    11761 ttgcaacctc gctgggttcc atcggaggaa aagccaatat tcatcaacag attcttgacg
    11821 gaaagtcata ccaggatgtg gactttagcg cagcctttga gtgctgctct actcctagtg
    11881 gtgtgatctc caaggaattt gagtgttatg gcccaaatat ttccgtatct acagcctgtg
    11941 cagcaggtac caattctatt ggatgtggat atgacatgat caagaatgac acttgtgaca
    12001 tggtcattgc tggtggttca gatccatttg aacagatgtc ttttagtgga ttcctttcct
    12061 taaagacgat cacgcagaat gaactgacac catttgatct gaaccgctct ggtatcgata
    12121 tcggagaagg cgcggcagtt gtgattctgg aagaattgga cagtgccctc aagagaggcg
    12181 ctaatattta cgcagaagta ctaggctatg gactgagcaa tgatgcatat catgcaacaa
    12241 gtccagatcc aaatggcggt ggtgcaagac ttgccatgag catggccatg aaggaagcag
    12301 gcattaacct gcaggatgtg aactacatca atgcacacgg cacaggcacc aagatcaacg
    12361 ataagatgga gactggtgcc attgcagaac tgtttggaca tcatgcttct gacattatga
    12421 tcagttctac aaagagtatg cacggacata tgttaggtgc aactggtagt atagaagcaa
    12481 tcgtttgtgc gcttgcaatc aaggaaggat ttgttcctgc tactaccaag acaaaagagt
    12541 taatggaaga atgtgagaac cttgacatcg tgctgggaac ttttagaaag gaacagattc
    12601 agtatgctgt atccaactct tttggatttg caggtaattc ttcatcaatt gtgataggac
    12661 ggtatgtatg ttaattccat ttaaaaaggc tgactgtcag atggttacca tcatgcagtc
    12721 agtcatgaag ttctttcaat acgaggctcc ttcggaaacc tattacctga tgggaaatgc
    12781 tagaatgctt accctcgcat tcttagatga tcacgtcagc ctgtttcgac aagggtttgc
    12841 ctatgtgaat gatgtctgct atttttcagg agcatgggac agcgattttc tgaccttgga
    12901 tgcagacgga tttatagaga aactaaatga aaaatggcat gaatgggcag atatgcagca
    12961 accgatgccg attattgtag gtctggtgga ttcggataag atttcccccg cgttttacgt
    13021 gttggtcggg tacaacaagg aaaatgcatt ttatgaattg ctcactgcta caggagaaca
    13081 ggttcttatg agtgagacac agatgaaacg agatcacaat aggtatggat ttgctacgat
    13141 tgatgtacca tacaattttc tggtgaagag ccagtattac agaactgtgg aaggtgccgg
    13201 cgttggaatc ctgcaaaaag caggattgac cctgagtcaa catttaaaaa tgacacaggt
    13261 gttagaaaaa ctggatcgaa atgcgaagga agagaatctg gaagctttac aggaagagct
    13321 gcagttacta ggtaccagat tcctcggtgg agatgtgagt aaaagcttaa atcgtataga
    13381 gtatggagag gctcttagga tggcaggcta tgagagcatg ggggaacagt accagatact
    13441 gggacagtat tgggaacagc ttctgacttc gcagatggag caacatattg tcaatatacc
    13501 attgcttaga agtattcttg acatggaaag gcagttaatc aaagagcaga aggagtcagt
    13561 gtaatgagag tattacttga tctggaacaa tatcatagaa tgggatccca ttgcctgaca
    13621 acctgcctgg ttacattgtt tcgccagcag ggaatcggta tgccagagga aatgtcattg
    13681 ggacttggca gtggacttgg ttttacctac gtaagacaaa aaggcggttt tatgtatgga
    13741 ggaagaggcg ggaatctgga acagaatctt gcctcttctt taggccttga attagtcgcc
    13801 aacagaactc aggataagga tatcgcatgg gagtacaaca gacagatgct ccttggttgt
    13861 catcccctga tctgtgaggt agacatggca cacctgccat atatggtgga gaaattaaag
    13921 acaaacggta gtggttttag cggacataag ctgatcctca ttggatttga tgatgagaag
    13981 aatgagactt atgtgttgga ttatttatgg aatgatgtag tagtagtgaa tacagatgac
    14041 tttaagaagg cagccagctc ttctataaag ccgatgtctc cagacaattc cagtctctgg
    14101 atgcagattc ccaaggagct gtatccgatg gaatacgcca ttcacagtgc cattggcgtc
    14161 aatgtgaatc agatgaagaa tccagtagga tttggacttg gactgaaggc gatcaaaagg
    14221 ttctacaagg aattaagaag ctggccagac atattacagg aagatacact tcgctatgaa
    14281 cttaacatgg cgcatcttgt atttgagaag gttggtacag gaggaggcaa cttcagaaga
    14341 atgtatgcaa gattcttgaa aaatagcgca acacttctgc aaaatgagca actcttagaa
    14401 gcctccaaga cttatacaga gcttggaaag ctttggaaga cggttgccta tgatcttcac
    14461 gaagcaagtg tggaggagaa acttctagac cataagatct ttagccgtaa ttatgagacg
    14521 ggagagcaaa taatgaaatt agagaatcag ggtatccaac agttggagag atatcttgag
    14581 ggaggaagaa catgttactg attgatgaaa tatataaatc attaccacat cgcttcccat
    14641 tcctaatggt tgataggatt gtcagcgtgg agaaggagaa gtcagtgata ggacttaaga
    14701 acgttacagt aaatgagcct tattttcagg gacattttcc tgacgagcct ttgatgccag
    14761 cagtcatgat cattgaggcc atgtcacagg ttggcggatt tatctttgac ctagataacg
    14821 aacgcggata tgtcatcggc gtggataagg caaaattcaa gagaaaagta ataccagggg
    14881 atcagttaat cattgagtgt gagaagattg cacatgttgg taccatggca aaagtaaaag
    14941 gggttgcaaa agtagatggt aaggtcgtgg caagcgctga gatcgcctat aattttgcaa
    15001 agatttcata ggagaaaata atacatgatt cagataaaag cattaaataa ggtatatgga
    15061 actggaaagg tacaatttca ggcattgaag aatgtggata ttaccatcaa agaaggagag
    15121 tttgtagttc ttgcaggtcc ttcaggatca ggaaaatcca cattattaaa cattattggc
    15181 ggtatggata ctgcaacttc tggttctgtt ctggtcaacg gacaggatat cgtaaagttg
    15241 aacaagagac agctgaccca gtatagaaag tctcagcttg gatttatttt tcagaaattt
    15301 aacctgattg atacattaac tgtttttgaa aatgtggagt tcactctgat gctgaagaaa
    15361 tggaagaagg cagagagaag agcacttgtt atggacatgc tgaagaacgt aggactggat
    15421 acgaaggaga agaacttccc taagaatctg tcaggtggac agcaacagag agttgccatt
    15481 gccagagctt tggtaggaaa tccagtggtg atcttggcgg atgagccaac agcgaatctg
    15541 gactccaaga acggtaaaga atgtattgag atgctgcata gattaaataa agagaagaat
    15601 gttaccatca ttctgaccac tcatgatcag agaattatcg atacttcaga taatgtcatc
    15661 tatcttgtgg atggtcagat tgatcaggtg agaacttctc acaagaacaa aggagaaaat
    15721 gcatcatgaa aatgattgaa ggattcaagg tgaagatcgg aacactgtgt atttcttctg
    15781 tgcttcgaga tatcaccaat catatgttag gagtcaatta tggtgaagag atttactatg
    15841 gcttaggctg tggtctgttc tttgcatata ccatgtccaa cgaagtggtt ggccttggtg
    15901 gatttacgga tctgattctt gataatttga gagacagtct gacactgact aaagtggaga
    15961 cttacgcccc tgatgatgtg gtgtttgata agattagatt tagtatcgat gcaggacttc
    16021 ccgttctggt atcaggtctt catttccatt ctaaggaaga tctggccttg gacacagaag
    16081 ctacagagaa attagacctt cctatgaact atcactatac catcattgct ggatatgatg
    16141 atgagaccaa ggaactgttt atggcagata acaagtcatc gggaaatgtt tcctatgaga
    16201 acttcttgaa atttagagat catagaaaca tgttaacaca attcttattt ccaccaacat
    16261 tggagcattt ggatgcaaga atctatgctg ccatcagaaa gctcaccgat tactggtacc
    16321 gtatgccaga gaatccaaag agttttgcag atgtgtatac cacggatttc ttacatctga
    16381 gcaatgtcta caacaccatg gaaggcttgg agaactttag aaagttattc cttcatgggc
    16441 ctgagatgga atccttagag aatttccaga aatccatgtt cttcatccag gcgatttctt
    16501 acagaggaac tggtggagat atgacaagag gattatacag cagattctta agagaaggtg
    16561 gtgccattac tggagaggat aagatgttag aagtatccaa gctctatgct acagcagcca
    16621 gagagtggag aaaattcttc aaaatcttcg acggtaatcc aacagtcatc tatgagcaga
    16681 ttaaggatga gacacaaaat agtgttttct ttgaagctat cgaacaggta tatcagtgtg
    16741 aaatgacagc gatgtcagca ttaaatgatc tggcatatgg aaaataagaa acttgaaatg
    16801 aaacagaaat atcccatgga gatgaatctt ggagtcctaa gagatataca agagaatagc
    16861 tgtgtgttcg acgtggagtt tagcaggaat gatttcatgg ggcagaaacc tctctggatg
    16921 ccagcctcct gtttcatgga acttttagga caggcagcag agtatctgat gcgctccaca
    16981 cagggagact gcaaaagata cttggtgcag gtaaatgagt ttacactgga tcctgagttc
    17041 tatcaggtga tggaccagaa tttcacactt cgtgtggagc tcacacagac atttggcaat
    17101 ctgaataaaa gtcgtgcatc cttatctcat ggagagagga gctactgtga gggaagcttt
    17161 atgcatagcg acattaccta agattgttat ggagattaca aaacatgaat ggatttgtaa
    17221 aaattagatt acaaagctta ttaaataaaa ctgcaatttc gactttgaca gaggctactt
    17281 tttcccaagg agggaatgtg ctgattctgt cacctcatta tgacgatgac gtcattagct
    17341 gttttggtgc catgacaaag cactatgagc agggggctca tctggatatt ctctatctta
    17401 cagatggtac taccagcaag gacagtggac ttaccaaaga ggagctgcat aagatcagaa
    17461 aagtagaggc tgcaaatgcg gtaaacacct tttttaagga tgtgaacctg gaacatttca
    17521 atcacgaaga tggtcatttc gctatgactt tggaagatgt gaccagactg agcaaactgc
    17581 tacaggagaa acagtatgat tacatctact gtccatccat cactgatact catgaagacc
    17641 acaaggagac ttataagttg cttcgacagg ctttactgga aagtggtctc aagtgcacga
    17701 tcagattata tgaattctgg tatcctttga agaaacccaa tgtgtatgta gactttgccg
    17761 actgcgaaga gaagaagtgg gagagtatcg cctgccatca gtcacagatg aaatatctga
    17821 attatgtgga actggcgcag actgtcaatg ctcatcgtgg attgcaggct gagcgcaagt
    17881 ggtgtgaagt atatgaggaa atgagttcag ctaagctaat ctgggatctg gttccttcgc
    17941 tgaaagccag cgtagtgatt cctgcttata ataatgaagc ttatgtggca atcatgttga
    18001 aagcgttgca gagacagact cttgatactt tttgttggga gattgttctg gtggatgaca
    18061 gtgaagataa cagaatgact caatttgaga agtgggagct tccgaatctt cgcgtgattg
    18121 agaaggaaca ttctggccgt gctgatgcca gaaatgtagg aatacagaat agtagaggtg
    18181 aagtgattat cttcatggat tctgacatga tcgtggaaga gtcttttgtg gagaaacact
    18241 atgcatctca tagagagaca ggtagtgata tcactttggg aaaagtcaat cacatctgtc
    18301 atgaacattt agaagaagta agaaaactgg tgctggaaga caggacaaag gaacttgaag
    18361 cttttgtcat gaaggatgaa tacctgaact tgacaccaat tgtttttcag aataaagaag
    18421 cggctgataa tatcggttgg gtgtgctgtc tgtttagcaa ctgttcggtg cgaagaaagg
    18481 tattggacaa agctggcgta tttgatgtga tcttcaaagg ctggggattg gaagatatcg
    18541 aactgggata tcgattcttc aaggaaaaat ttagcttttc ctatgaggaa gacatcgcca
    18601 actatcatgt ggaccatgcc accaacagtc agcagatgct tgtggaaatg ggaagaaatt
    18661 tgaaaaggct ttcgaagaag catccagacg cggccatcaa aagctatatg agctttgtgg
    18721 ctggattcaa ggatcttcag gaactgcttt gcgatgtggc aaagaaggag attgcatttg
    18781 ataacggaag tggagtgtac ttcagaccaa tcagttatac gaaatcaaaa gcctaaaata
    18841 gtgtgggagg aaaaaatgat tactttaaaa ttagcagtac gaaccatcac aatgaaattc
    18901 tccagatatg ttttgttgtg cattgtgttc tttgtatcaa ccatagctct gatcttcaat
    18961 ttcattggag cacatgccat taagaactcc atggaaggag cctgtattcg tattttcacg
    19021 ggaaatgtca tggtgaaaaa tgtggagtac gattaccgac tgggacttgc ttcctcagga
    19081 gatcccaagc ttgtggagca tgtggctgat tatattgaag cctatgagaa ggaagaggga
    19141 gtcactggct gtgtggctcg tgtcagacga ggcgtacagg ttacttctga gaaaacggag
    19201 tatatgaatc tcatcggtgt agatacagac agggaagtga aatattctga gttcaaggta
    19261 agagaaggta aggttaccat gaaaagtgga gaggccatca tctctaagac ttgtttggac
    19321 agaatggatc tgaccattgg cgacaatgtt tatatcaata tggtgtccgc ccagggaatt
    19381 cctatgagaa aggaatacga aattgtgggc gtgatcgata ataccaatat gaacttttta
    19441 agacaggacg agatctacat cccatatcag gatgccctgg atcttcttca gatggaggat
    19501 gttgcaacag agttactggt gtatacaaaa gacaaaactc cttctgatga gcagcttact
    19561 acttttaaca agatagcaaa ggacaaggat attaaagcat atccttgggt agaaatagga
    19621 aatgagatta tctatgcttc tttgggtgct tatgcagcga ttctgttctt agccattgcc
    19681 tgcgccgtga tcatctgcgc tttggtttac aatctgacat ctatgtcgat ttatagccag
    19741 attcgtatga tcggaactat gttggctttg ggtatgactc atggaaaagt gttagtgaag
    19801 ttcatctgtg agaatctgct tgtgggcctg ttatcctgtg gactcagcgc tgtgcttgcg
    19861 attcttggta ttcaggctat gtctagcaga cagattccat taggtgtggc tgcagagatt
    19921 tttggtaatg attatctgac tcttcacatt gattatcgag tgattttcct tgtggctttg
    19981 tcagtagcat ttttcagtat tattagtact ttgattgcct tctgcaagat tcgcagtatt
    20041 cagccaatcg aagcgattat tcaataaata accttcaatg ataggtagga gaaagaatat
    20101 gggaaatata gtagtagtag aagctttagt gaagaaatac ggacagttta ctgcggtaaa
    20161 ccacatgaac ttagaagtga aggaaggaag catctatgga ttcttaggac ccaatggagc
    20221 tggtaaatct accacattaa gtatcatagc tacattgctt cgcatgaatg aaggtcacgt
    20281 taccatagat ggtctggact tagaaaaaca gaagagtaag attagacagc tcattggatg
    20341 ggtgcctcag gagattgtac tctatccaag aatgagcatt cgcgagaata ttagattcta
    20401 tggttctctg tatggacttc atggagccaa actggagcag gcttgtgagg aagccttgaa
    20461 agtggtttct cttgatcagg atacaggaag aaaagtgatg ggattatctg gtggtatgca
    20521 gcgaagactg aatattgcct gcggtattgt acatcatcca aagctgatca ttatggatga
    20581 gccaacggtt ggtgtggatg cacagtctag agatctgatt atggactcca tcaaatcttt
    20641 gaatcaggca ggatcttcta ttatctatac gtcacattac atgcatgaag tggaagaact
    20701 gtgcgatgaa attggcatcg tgaataaagg ccagatgatt gcccgtggaa cctatgaaga
    20761 actggctaca gaatatgctg acggcaattg cttctgcgtg gatacctcca aggaagcact
    20821 gcagtttcat atgcaggaaa taatgggaaa atatgtagac ctgcatgtat ctgtagatga
    20881 gaatacctta aaattcctgg tacaaggaga aaaccacatc aaccgtattt tgcaggatat
    20941 gatctctatg aatatgcctg tatatcgact taccagtgag cagatgtccc tggaagatat
    21001 tttcctaaga ctaacaggca agcaaactgc acaataggaa agaggtggca ttttgattat
    21061 tttatatgag ataaaaaagt tttttaaaga gattcctaac ctggtgtttc tattggcact
    21121 tcctattatt atgctgtatg ttctgggaaa gacttccgct ggatttacta cggtggtttt
    21181 ggaaaatatg caggagtttc ctgcacagta tgagctaatg aatctgaaag aagtgatgat
    21241 tccatcctgc tatggtgtta tggattattt tggaatcact atgctgatga tgatgtcatt
    21301 tttgacttgt attctgggag ccaattccta tagtgaagaa tatcgtcaga agaccataaa
    21361 tcgtctgctt gtagcaaagc attctcgttt tcgtatcttc atagagaaaa ctgtaggact
    21421 acttctggtg gctgcatttg agattggtgt tttcctcgta atcgcgaaag gaatctacaa
    21481 ggtaagcttt gcgacagtga gaagagaaga ggtagcaatc cttttacttg ctttcgtaaa
    21541 cagtatactg atgctgtttc ttggcaatgt gattggtatg atttttagaa aaaatacttt
    21601 aatgatcatc atgccattat tctgtatcat gatgcttttt ggcggtactt tcacgggaaa
    21661 tctttatata gagggactca gtgactggat gccgatctat cagttgcaga tggcagcttt
    21721 tcgtgtagga acactgcata cctatgattt gttcaaaaca gtattatata tagaaggaac
    21781 tgcttcgatt ttgatggcag gtgttgcgtt ctggcttttc ttaagacagg atgaagttag
    21841 ataagaatgt ggagagatga aaaatgttat taaaaacaga atcgatcaaa tgggtttttc
    21901 ttttgtcctg tatgttcagt gtgatccttt gcattgtttt ttcaatcacc tataaagcaa
    21961 atcttaaaaa agatgataga agtatcacta ttagtgtctg ggatgaaagc aagagccaag
    22021 aatcagagaa acttttatcc tatatggaaa atactttgga tgctaagatc ttactgggag
    22081 atcagaagca gatggagaat cagctcatta cctttcgagc tatggtggga gtaaagattc
    22141 cagaaggatt tgctcagggt gaattgcctc aagtcattca ttttgaagat gataagatcg
    22201 cgcagatggt gtcttcgctg attgatcagt atgtttggtt acaggatgat gtgactccta
    22261 aaaaggtaga tgtggaggca agaaaagaga acgcagtagc aaaagctttg aagactacca
    22321 tgggatttct tcctcaggct ttgatgatta tggcaatctg cctgtctatc tttctcgtga
    22381 cagagaagca ggaaggaaat ctaatgagaa tctatatttc tccagtcagc tttctgcagt
    22441 atatgttagg aagaggagga ctgtctgtgc tggtttcttt aattccagcc ttcgccttat
    22501 ggggtatggt agccttttat ctgggatatg atgacataag tgtcatgcaa gcttttgaga
    22561 atatggtact gtttaccata ttcatgatgc tgacagcttt ttacctgggc cttcgctgca
    22621 cgacgcagaa tactattttt ctgggaatcg tggggctgac ttctgtggga tctatcattg
    22681 gaggatgctt tttctccatc gatgggactg tcaaagtgct ggaaacgatt gccaaggtgc
    22741 ttcctcatta ctggttgatg aaggtaggac aggggcagtt tctgcttatt tatatagtga
    22801 ttatgattgt gcttaatttt gtgacttatg agaagctgaa taaaaatgga ggaaagatcg
    22861 gatgatttta gaaggtgcga attttaaaat cgtaaatatt agtggaagcc ctcacggggg
    22921 cattggcaac acacagtttc tggtaaaaac atttgctcag agactggaag agaaaggcgc
    22981 caacgtggag ctcgtcaacc attatgtggt gaaggaacat gtggaggagt gccgtggatg
    23041 caccagatgt atgagaaagg gagagtgcgt catgtctgaa aaggatgatg tcaaagacat
    23101 ggtgcaggat ttgctttctg ctgacttggt cgtattctca tctccgattt atgtactgaa
    23161 tgtcacaagc cttatgaaga agttctttga cagaactgct tatatgactc acagaatcgt
    23221 gttggagaat aagcttggat tctatgtatt atcgtcccag ggccttggga ttgacacggt
    23281 atctgcttat atgcagtctg ttatggaagc tatgggtgtc acagtactgg gctctattaa
    23341 gggaactgct attttccata accagttttt gaatcaggag gagattgatc agtctatcga
    23401 tgagattctg acctctttgg agcaggattt ctataaggag acgcagctct acagcgagag
    23461 cgagaagaag agacgtgaga agttctcttc tctcatggat caggaagaaa tatccaagaa
    23521 attgttccat gaagattata aatattgggc aaacaagaaa gaaacctctg aaatcttgta
    23581 aaaaacttga gaaaaatcgt atatttatgc aaaaaaatgt tgaccgacag ggcatcagcg
    23641 agtacatcta taaaagatgt agatcaacaa gttttaaaag ttaatagaag aggaaaagaa
    23701 atcgtgaact gggttacgag attgttctcg ttaactctaa tccggcgacc attatgacaa
    23761 accctgaaat cgctgatgtt atctacattg aacctttaaa tgtagatcgt cttgagcaga
    23821 ttattgctaa tgaaagacct gatgcggtac ttcctaacct gggggggcag tctgggctta
    23881 atctttgttc tgaactttca cagaagggca tcttaggcta ttgatttgcg ttttcctgtc
    23941 accgcttttt tgcacttatt ttctcccatt tattgagcgt tcccggggcg ttttctgtca
    24001 ataacatcaa atttattact gcactttcac gtccaagcct tctagcatca gaaaatttct
    24061 gatttaattc ggtggcttat agaaaatagg cattgtattc attatcacag caaatgcgtc
    24121 cagatgccat tacaagatgg gttttaccaa caccctgtgg tcctataaat gctatatttt
    24181 tatgagcata taaactagat agtgtcgata gttcttttaa tgtatcaaca tttttaccat
    24241 tgattctact aaaatcataa ttatcaaaag tcttaggatt ttttaaaggt attctactca
    24301 tttgtttaag catatttaca ggattattat gtttcctgtc ctttaaatat aataagaatt
    24361 ctgaaattgc tagtgattgt tcttcagtgt atttgttttt ttagtattat gtttgctaag
    24421 tttgctatag aagaaatttt accaattgtt attgcaaatg cagcatgtgg gatgaaccta
    24481 gaatttccga gaaaattgta tgtgttgaca tttgcaacta tacttggatt atacataata
    24541 atagaatatc attgtagcga ttgtaaacta agtgctagca tcctttggca taactatagt
    24601 ccacaattta aatatattaa agattaagga atactaatat ttgaataaat aaggagtaga
    24661 aggatgaaat gtaaaaaaat aataaacacc aaaaagatgg ttttgtcagc gctattactg
    24721 gcattgggta tgatattacc tatgttgaca atgcaaatac ctactattgg aaatatgtta
    24781 ttgccaatgc atattccggt attattgtgt ggatttatat gtggtgcacc ttatggtgcg
    24841 atgataggtt ttgcattacc aataataaaa agcattgtat ttggtactcc cattttgatg
    24901 ccaaatgctt tggcaatgtc atttgaatta ttatgttatg gttttttttc gggctttttt
    24961 tattgtttat taaaaaaaag aaagggacag atttatgttt ctctaatatt aacaatgttt
    25021 attggaagag tagcatgggg gtgtgctaca tatatactat attatatatt gggtaataga
    25081 ttgacgtgga aaatattttt aacgcaggca tttattaatt caatattagg aataataatt
    25141 caattaatga ttgttccata tattacaaga attgtaaaga tatatatagg ggaaaatgat
    25201 tgctaatgaa tgaaatagtt atacaaaaaa tgtgtaaaaa gtcttttgag ccagtagtaa
    25261 aaagaattga tcaattactt aaagaaaaag atgaatatat tttagttgca atcgatggta
    25321 aatgtgcagc tggaaaaaca acattggctt attatttgaa agagttatat aaatgcaacg
    25381 tatttcatat ggatgatttt tttttgcaaa tgcagcaaag aacagttgaa agattcaatg
    25441 aagtgggtgg aaatattgat tatgaacgtt ttaaagagga ggtattaaaa ttcataattc
    25501 aaaaaaaaga tgtaatatat cgtccgtttt cttgtaaaac attaaatttt caagaggcaa
    25561 aaataatgga gttccatagg cttaatatta tagagggctc ttatagtcag catccatact
    25621 ttggtaatgt atatcattta agagtatttt tggatattcc agaggatttg cagatagcac
    25681 gcattcgatt tagaaatgga gaaagaatgc ttgaacgttt taagaacgag tggattccta
    25741 aagaaaatga attctttttg aaatatgata ttaggcgaca aagcttaatt attaatggtg
    25801 ctagaatata aatagtacaa gccaaaatga gaaattccaa atacacataa gcatggtaca
    25861 atagagacat gctgaaggag gatctcatat ggcaaagcaa cacgacaaac aatttaaact
    25921 tgatgcagtc cag
//
