LOCUS       gnlProkkaCAKJMPPP_78   21849 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CAKJMPPP_78.
ACCESSION   gnlProkkaCAKJMPPP_78
VERSION     gnlProkkaCAKJMPPP_78
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 04:39:13
            Original ID  :: gnl|Prokka|CAKJMPPP_78
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 117326
            Orig. end    :: 139175
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21849
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11849]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11849
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21849
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21849
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             350..682
                     /locus_tag="ctg78_90"
                     /transl_table=11
                     /translation="MPVSVARSLVIIAAVAGTIFFTRLCPFLFFPPGKPIPPVIQYLGK
                     VLPPAVIGMLVIYCLKAVSITSYPYGLPEFIAVAVVILLHVWKRNNLLSIGVGTVLYMV
                     LIQAVF"
     CDS             700..1983
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264:diaminopimelate decarboxylase (Score: 256;
                     E-value: 6.8e-78)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_91"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 3.2e-29, bitscore:
                     94.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 7.6e-21,
                     bitscore: 67.2, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKPFVTKEQLEEIVKKYPTPFHLYDEKGIRENAKAVKEAFSWN
                     PGFREYFAVKATPNPYILDILKEYDCGCDCASLTELMLADSQGFDRKHIMFSSNDTPAE
                     EFKFANELGAIINLDDFTHIDFLEKTIGKIPETISCRYNPGGVFKMSNGIMDNPGDAKY
                     GFTHEQIIEGFKILKEKGAKHFGVHAFLASNTVTNEYYPKLARQLFELVVELRDKTGCD
                     IQFINLSGGVGVPYTPDQTPNDIRVIGQGVKEAFEEILVPAGLGNISIYTEMGRFMLAP
                     YGCLVTKAIHEKHTYKEYIGVDACAVNLMRPAIYGAYHHITVMGKEDEPCDHKYDVTGS
                     LCENCDKFAIDRMLPKIDMGDLLVIHDAGAHGFSMGYNYNGKLRSAEVLLKEDGSTQLI
                     RRAETPDDYFRTFDCFDILKDMKHPERK"
     CDS             2011..2757
                     /locus_tag="ctg78_92"
                     /transl_table=11
                     /translation="MCIDELRFEAAKNRVIGINRERQGIGTLSEKTVHAVLKNYYAPDT
                     DMHEIPIENFVADIFTGTEIIEIQTRSFQVMRRKLDAFLKIYPVTIVYPIPHVKWLSWI
                     DEESGEMSPKRKSPKKGNPYVAFKELYKIRPFLKNENLRFRFALIDMEEYRLLNGWSKD
                     KKKGSERYDRIPVQFVEEVCIERREDYMQFIPFDLPEPFTTKDFSKSAKIPLSLAQTVL
                     LILTDLEIVDRVGKQGNSYLYKVCEI"
     CDS             complement(2777..3070)
                     /locus_tag="ctg78_93"
                     /transl_table=11
                     /translation="MGKALILGKDTKHLDKDIELCRTTNERISDQAAQLLIENQIPFMR
                     SFIKIPFFLREKYRGAHQFYVIHTNRNRYSQARHTLDHMDSVFRRRLIVSNY"
     CDS             3210..4493
                     /locus_tag="ctg78_94"
                     /transl_table=11
                     /translation="MKKKVVVLMLCTMMAVTALGCGGKKNDTAEGTEAAESVNGTETAE
                     GTETVEYESPSYDLDPSDYVTLCDYSKVPVTITGDYDVDDQDAKDYFEQMFSYYGPFYV
                     ADDTKTTVGDGDIVNVDYVGKLDGVAFDNGSAEDQNIDVDNNCSAGSQSSSFIDGFTDD
                     LKGASVGDVIDSDVTFPDNYGNADLAGKQVVFTFTVNSIQKEMTLDDVDDDFAQKQFQA
                     DTVDDMYAQIKSFLENQASSNKDSDTYTAVQEYLLENCKVDIPEDYLTARVNDYEKQYV
                     QNYCDGDASKLEDYVSSQYNMTLDEVRQEWKSGMEKNISMEFITGAIAAKEGTELDEDG
                     FSSYVQTLMSNNSLSSEDDLYKNYGYGDAAYGEKYLRQVYVDNLALQSVKDNADVTVEA
                     PAETESTEGTESAEPQEAVDAAETETAN"
     CDS             4548..5939
                     /locus_tag="ctg78_95"
                     /transl_table=11
                     /translation="MDMVNVRDLFRKQEEYVDQTVTIGGWVRSIRNSKNFGFIVVNDGT
                     FFEPVQVVYSNVLENFDDVEKLNVGAAIIVTGKLVATPGTKQPFEIQAEKIEIEGVSTP
                     DYPLQKKKHSFEYLRTISHLRPRTNTFEAVFRVRSLIAYAIHKFFQERDFVYVHTPLIT
                     GSDCEGAGEMFQVTTLDMNNLPKNPDGTVDYTKDFFNKPTNLTVSGQLNGETYAMAFKN
                     IYTFGPTFRAENSNTTRHAAEFWMIEPEIAFADLEDDMILAESMLKYIINYVLENAPEE
                     MAFFNNFIDKGLLERLQHVANSDFARVTYTEAVEILEKHNDKFEYKVSWGTDLQTEHER
                     YLTEEIFKRPVFVTDYPKEIKAFYMKMNDDGKTVAAVDCLVPGIGEIIGGSQREDDYDK
                     LLARINELGLKEEDYQFYLDLRKYGSARHAGFGLGFERCVMYLTGMSNIRDVIPFPRTV
                     NNCEL"
     CDS             6204..6857
                     /locus_tag="ctg78_96"
                     /transl_table=11
                     /translation="MLQIGIREPGSAITHFIAMMMAIFATSPLLVKAALNGNHTTILAM
                     AVFMGSMVLLYGASTVYHSLVVRDKILKIFRKLDHMMIFVLIAGSYTPVCLIVLGGKSG
                     YTLLAAVWGIAAAGMLIKVLWINCPKWFSSVIYIAMGWVCLFVFRELLATLSQAAFLWL
                     LAGGLIYTVGGVIYALKLPVFNAKHSQFGSHEVFHLFVMAGSICHFVFMYQYVA"
     CDS             6978..7856
                     /locus_tag="ctg78_97"
                     /transl_table=11
                     /translation="MRYTLENENLKVEIDSFGAEIKSVKRKSDNFEYMWCGDKKYWGRT
                     SPVLFPFVGAPKNKEYRYDGKTYTMGQHGFARDMEFTLEAQTEENISFVLTDTAETCEK
                     YPFHFALHIGYELCKNEVKVNWTVENTDTKELYFSIGAHPAFNCPVHGEENKTGYGLKF
                     GDLADTIHHHGNTPDGMAVMEDKVLALKDGCVTFTEGFFDECTYMVEGKQTGEVSLLDR
                     EGIPYVTVKFDTPLFAVWSPEGKNAPFVCIEPWYGRCDATDFTGTLQQRDYENMLPQGG
                     TFKAAYSIAYL"
     CDS             7975..8367
                     /locus_tag="ctg78_98"
                     /transl_table=11
                     /translation="MNIQSKMKTRDAKNNPVTAVLVSVLVMFLLSCLFLLLLAALLYKF
                     DLSESAVKVGIVVIYIVSGVIGGFFMGKIMKTQKFLWGFAAGAIYFCILFLISVLVKQG
                     VSMELPKVATTFILCAASGMAGGMIS"
     CDS             8510..9901
                     /locus_tag="ctg78_99"
                     /transl_table=11
                     /translation="MERQKRQGAEYEFYGKLPLKKAIPLGLQHVLAMFVGNLTPILIIS
                     GACGIAGEEFGSLQVDLLQNAMLIAGIVTLIQLFAIGPVGGKVPIIMGTSSGFIGVFNS
                     VVQVMGGGILAYGAIMCASVIGGLFEGILGFLLKPLRRFFPAVVTGTVVLSIGLSLIAV
                     GVNSFGGGNTANDFGSVENLLLGAAVLLIIVAVKHWMKGMASASSILIGIVAGYIIAAI
                     MGLVLPTTAVNADGVEYTKAWVLNWDKVANAAWFSVPKLMPVKLVFDWRAIIPVLIMFV
                     VTAVETVGDISGVMEGGMGREATDKELSGGVICDGIGSSLAALFGVLPNTSFSQNVGLV
                     TMTKIVNRMALASGAVFLILCGLFPKLAALISIMPQSVLGGAAVMMFSSIVISGIQLIT
                     KEPMTMRNITIVSVALGLGYGIGSSSGILAHLPQGIQLIFGGSGIVPAAIVAIIFNIIL
                     PKDAE"
     CDS             10001..10189
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: SCIFF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR03973"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_100"
                     /sec_met_domain="TIGR03973 (E-value: 1.3e-26, bitscore:
                     85.2, seeds: 29, tool: rule-based-clusters)"
                     /sec_met_domain="SCIFF (E-value: 1e-26, bitscore: 85.5,
                     seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAYPMCAEITKKERSIMKHVKTLNTKRLQNTIKKGGCGECQTSCQ
                     SACKTSCTVGNQSCEHK"
     CDS             10476..11849
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Quinohemoprotein_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg78_101"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 1.6e-34,
                     bitscore: 111.0, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Quinohemoprotein_rSAM_RRE (E-value:
                     1.7e-10, bitscore: 33.8, seeds: 15, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.9e-16, bitscore: 52.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 8e-13, bitscore: 42.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 8.2e-18, bitscore:
                     57.6, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHQYKNNGYDIVLDVNSGAIHVVDDVTYDVIEMFDQSQPESYAR
                     DEIVSALSGKYGKEEVEEAIDEVQTLIDEESLFTKDTYENYIMDFKKRPTVVKALCLHI
                     AHDCNLACQYCFAEEGEYHGRRALMSFEVGKKALDFLIANSGNRRNLEVDFFGGEPLMN
                     WQVVKDLVAYGREQEKLHGKNFRFTLTTNGVLLNDEIMEFCNKEMANVVLSIDGRKEVH
                     DKMRPFRKGAGSYDLIVPKFQKFAESRHQDKYYVRGTFTHYNPDFAADVLHLADLGFKQ
                     ISVEPVVAEPSEPYAITEEDLPQLFEEYDKLAAEMVRRHKEGDDFNFFHFMIDLEGGPC
                     VAKRLSGCGSGTEYLAVTPWGDFYPCHQFVGNEKFLLGNVDEGIKNTEIRDEFKCCNVY
                     AKEKCRKCFARFYCSGGCAANAYNFSGDICGAYDIGCELQKKRIECAIMIKAAEADCE"
     CDS             11875..14034
                     /locus_tag="ctg78_102"
                     /transl_table=11
                     /translation="MKKSKAAVILVAILAAFAGLAYYASIILSSTGIGEEMSIPLGLDL
                     SGGVSITYQVMDENPSAEDMSDTIYKLQKRVESYSTEASVYQVGDDRIAVEIPGVTDAS
                     KILEELGNPGSLEFQLSDGTVFMTGDQVADAQAATTTDQYGNKQYVVQLTLTDEGAKTF
                     GEVTSENVGKALPIVYDGEVISYPTVQEAITGGTAQISGQSTFEEAQTLATQIRIGSLS
                     LQLSELESSVVGAQLGSQAISSSLKAAAIGLVIVMVFMIIVYAVPGVAAALALAIYTAL
                     VIATLYLFEITLTLPGIAGIILSIGMAVDANVIIFARIREEIASGKSVITAMKNGFHKA
                     MSAILDGNITTLIAAIVLMGLGSGTVKGFAYTLMIGIILSMFTALVVTRWILYSFYWLG
                     MRDEKFYGRAKERKTINFLQKRYVFFAISIAVIAAGFIGMGVHKASGQNSLNYGLDFMG
                     GTSTTADFGKEYTIEDIENDIIPVVKEVTGDSNIQANKVEGTTQITIKTRTLSKEERDD
                     LNNKLADSFDVDESTITFQSISSTISGEMRADAVKAVIISTICMLIYIWFRFKDIRFGA
                     SAIIALIHDVLVVLTVYALMRISVGNTFIACMLTIIGYSVNDTIVIFDRIRENLALKHG
                     KQTREDLMEVANRSLTQTLSRSINTSITTFIMVFMLFLLGVASIREFALPLMAGMICGA
                     YSSICIATELWYVMKVHLGKNKITE"
     CDS             14220..14498
                     /locus_tag="ctg78_103"
                     /transl_table=11
                     /translation="MDTIAAYLIFLNLVGFLIMGEDKRRAKMHRWRISERMLFLVSILG
                     GSIGTWAGMYVFRHKTRHWYFVIGIPLILILQIAGAIWLYRQGLYHL"
     CDS             14638..15879
                     /NRPS_PKS="Domain: Aminotran_1_2 (77-368). E-value:
                     1.2e-15. Score: 49.4. Matches aSDomain:
                     nrpspksdomains_ctg78_104_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_104"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.5e-15, bitscore:
                     49.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTLEDIQAVDMEVANAITDEFERQNSHIELIASENWVSKAVMSA
                     MGSVLTNKYAEGYPGKRYYGGCECVDVVEELARERAKELFGCEYANVQPHSGAQANMAV
                     QFAILKPGDTVMGMNLDHGGHLTHGSPVNFSGTYFHIVPYGVNDEGFIDYDKVEEIAME
                     CKPKMIIAGASAYARTIDFKRFREIADACGAVLMVDMAHIAGLVAAGLHPSPIPYAHVV
                     TTTTHKTLRGPRGGMILSSQEIADKYNFNKAIFPGIQGGPLMHVIAAKAVCFKEALQPE
                     FKVYQQNIIDNAQALCKGLLSRDIKIVSGGTDNHLMLVDLTNYDQTGKAVEKLLDSVNI
                     TCNKNTIPNDPKSPFVTSGVRLGTPAVTSRGLNTEDMDQIAEAIAMMIKEGEPAADKAC
                     AIVKSLTEKYPLER"
     aSDomain        14869..15741
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg78_104_Aminotran_1_2.1"
                     /evalue="1.20E-15"
                     /label="ctg78_104_Aminotran_1_2.1"
                     /locus_tag="ctg78_104"
                     /protein_end="368"
                     /protein_start="77"
                     /score="49.4"
                     /tool="antismash"
                     /translation="RERAKELFGCEYANVQPHSGAQANMAVQFAILKPGDTVMGMNLDH
                     GGHLTHGSPVNFSGTYFHIVPYGVNDEGFIDYDKVEEIAMECKPKMIIAGASAYARTID
                     FKRFREIADACGAVLMVDMAHIAGLVAAGLHPSPIPYAHVVTTTTHKTLRGPRGGMILS
                     SQEIADKYNFNKAIFPGIQGGPLMHVIAAKAVCFKEALQPEFKVYQQNIIDNAQALCKG
                     LLSRDIKIVSGGTDNHLMLVDLTNYDQTGKAVEKLLDSVNITCNKNTIPNDPKSPFVTS
                     GVRLGTPAVT"
     CDS             complement(15968..16792)
                     /locus_tag="ctg78_105"
                     /transl_table=11
                     /translation="MKLFKQITCAVLTLCLCAGLLLIPSAPVSAATGPSAPKAVDVSYY
                     KNYPMVNDSAISVQLGTNGKNIKNIKTSSKNLKAKVTRLSLSSSSNSGYVGVYAKKTGK
                     YTVSFDVYNAQNKKIKKFTVKVNVTEPTFSNNSPFKSVTFNNKEYDYAKAVYNKNSVKV
                     NVKMNKGYKLKKIEYSTYSKPVAKTNSSYSTTYSNSEITKKVKNGKSIQLGHYGYYYGH
                     DYSYAYGTYSYESYSRDGDIMAPTIVKITYLDKNKNTISTSYTLYRIADDVK"
     CDS             complement(16814..17560)
                     /locus_tag="ctg78_106"
                     /transl_table=11
                     /translation="MKIFKRTVSLFLAFCLCAGMLLLQPQSTVSAAVRNKPTTTVLRMS
                     SNSFDSSAIYVNLPKAKVCYIKNIKTSSKNLIAKNTHYYTTSSDDTYTDTFASIGLYAK
                     KTGKYKVTYNICDKSGNKLSSGKVTVYVKNDLPVKSVKFAGKEVNYALTSKKSGKLSVK
                     MNKGYTLKKITVTTYNKAGKEVVKTMKNNSTLKLGEYAYIFDNSYSSGRNYSTSLAART
                     KITITYIDKYTKQECESIYSISRLAK"
     CDS             17836..19134
                     /locus_tag="ctg78_107"
                     /transl_table=11
                     /translation="MKKQSKGVPTNRDIRWDRLDNTAHLFPVIAGESMSNVYRISVTLK
                     EEINPELLQRALDMVLPKFDGFNLRLRQGVFWYYFEENGKAAPKVRMENNFPCRYIQQN
                     KNRSYMFRVTYYKCRINLEVFHVLTDGMGGINFLKELTYQYLRLAHKDLQEKLGDSLSV
                     DTSLNREDSFLKNYKKSSAKGYQTKKAYLIRGEKLRPGEFGVMHGYMKIPELKRVCHAM
                     GISINEYLVSVYIWSVYTECLHGMPSKCPIRVAVPVNLRPYFNSITTKNFFVMVSAEFH
                     PTKETYTFAEVAAIVKESLRSQINRENLEKLFSYNVSNEKLLIARVVPLFLKNLAMKYV
                     YTTSALANTATITNIGNISVTEEYRPYVEMFHAFLAMSKGQHLKGTICSYGDTLVFSFS
                     YDLVDASVQRGFFRKIASDGIAVEIKSNGVNYE"
     CDS             19127..19792
                     /locus_tag="ctg78_108"
                     /transl_table=11
                     /translation="MSKCRNCNVEISDETERCPLCGSVLEYTGEVENMYPDVRVHTRKM
                     TMISKIYLFCALLVEVLLIYINVVTESQIAWSAITGLGFFYGYMLIRFAILGKTGYRAK
                     ITVLTLMAILIVIAIDFLVGYRGWSVNYALPSAIILVDVGIIICMIVNRRNWQSYMMWQ
                     IFMILCSIVPVILIFTGIVTAQLFALIAFAFSLFLFLGTLIIGDRRARVELKRRFHVR"
     CDS             19828..20754
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1066:alpha/beta hydrolase domain-containing protein
                     (Score: 222.6; E-value: 1.1e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg78_109"
                     /transl_table=11
                     /translation="MRESEASIRGRVMRDLIAHVTNDHLIGKKIKNGELRKKIGDSEPP
                     WKCPDCFSLDVIEMDNFSMEYLQAKENPNTEKVILQLHGGGYVGAMRNAYRMFAGLYCE
                     VSHGMSVLTPDYRVAPEHPYPAALEDAYAAYCYLLEQGWFSEQIIIAGDSAGGGLAMAL
                     CHYLKDHGKQLPCGIVAMSPWTDLAASGESYETNFERDPLFGKTRDSLIYNKDYIGDND
                     PYNAYISPLYGDFRGFPPMLIQVGSYEMLLSDSVDVAAKAREQGVKVRISIYEGMFHIF
                     QMAAKMLPESKRAWVEIGKFIDVLLND"
ORIGIN
        1 aaggatgtgg aagaaggaca gtttttattt gcaatcgcac tgttagacca gctttactgg
       61 atcatcggtt ccgcaatcgg ggcactgctt ggatcagtac ttccaatcga cacgacagga
      121 attgattttg cgatgacggc gttgttcgtc gtgatcatgg tggagcagtg gatggagtca
      181 aaaaaccgtc cgagcgtact gatcggactt ggatgcggac tggtttgtct tctgatcttt
      241 ggcgcagaca attttattct gccgaccatg atctgtatta tgctgatcct gcttccgtgc
      301 agaaagtttt tgaataaaga attagatcag aaaaaggagg tagagcatca tgccggttag
      361 tgtggcgcgt tcacttgtta tcattgcagc agttgcggga acgatctttt ttacaagact
      421 ctgcccgttt ttattctttc cgccgggaaa accgatcccg ccggtgatac agtatcttgg
      481 aaaagtattg ccgccggcag tcatcggaat gttggtgatt tattgtttaa aggcggtaag
      541 tatcacatcc tatccatatg gattaccgga gtttatagcg gtggcagtag tgatactgct
      601 tcatgtctgg aaacgaaaca acctgcttag tatcggcgtc gggacagtgc tttatatggt
      661 gctgatacag gctgtatttt aataaaatgg aggaatatta tgaagaagaa accttttgta
      721 accaaagaac agctcgaaga gatcgtaaaa aaatatccga caccgtttca tctctacgat
      781 gaaaaaggaa tccgtgaaaa tgcgaaggcg gtcaaggaag cattttcctg gaatcccgga
      841 tttcgtgagt attttgcggt aaaggcaacg ccaaacccgt acatccttga tatcctaaaa
      901 gaatatgact gcggctgcga ctgtgcatcc ttaacagaac tgatgttggc agactctcag
      961 ggatttgaca gaaagcacat catgttttcc tcaaacgata cacctgccga ggagtttaaa
     1021 tttgccaatg aacttggtgc gatcatcaac ttagatgatt ttacccacat tgacttttta
     1081 gagaaaacga tcggcaaaat tcctgagacg atcagctgcc gttataatcc gggcggagtc
     1141 tttaagatga gcaacggcat catggataat cctggtgatg ccaaatatgg ttttacacat
     1201 gagcagatca tcgagggatt taagatctta aaagaaaaag gcgcaaaaca tttcggcgta
     1261 catgcattct tagcgagcaa caccgtgaca aatgaatatt acccgaaact ggcaagacag
     1321 ttgttcgaac tggttgtgga actgcgtgac aagaccggat gtgatatcca gtttatcaac
     1381 ctttccggcg gtgtcggtgt gccttataca ccggatcaga caccgaacga tatccgcgtg
     1441 atcggacagg gggtcaagga agcttttgag gagatcttag ttccggcagg acttggaaat
     1501 atctctattt atacagagat gggacgtttc atgttagcac cttacggctg ccttgtgacg
     1561 aaagcaatcc atgagaaaca cacctataaa gagtatatcg gtgtggatgc ctgtgcagtc
     1621 aacctgatgc gtccggcaat ttacggggca tatcatcaca tcaccgttat gggaaaagag
     1681 gacgagcctt gcgaccacaa atatgatgtg acaggttccc tctgcgagaa ctgtgataaa
     1741 tttgccattg accgtatgct gccgaagatc gatatgggag atctgcttgt gatccacgat
     1801 gcaggagcac atggtttctc catgggatat aactataacg gaaaactgcg ctccgcggag
     1861 gtattgttaa aagaggatgg ttccacccag ctgatccgcc gtgcagagac accggatgac
     1921 tacttcagaa cttttgactg ctttgatatt ttaaaggata tgaagcatcc ggagagaaaa
     1981 taagacttca ttctgcaaga ggagtgtgtc atgtgtattg atgaattgag gtttgaagct
     2041 gcaaaaaaca gagtgatcgg gataaacagg gagcgtcagg gaatcgggac gctctcagag
     2101 aaaacggtac atgccgtttt gaaaaattat tatgcgccgg atacggatat gcacgaaatc
     2161 ccaatcgaaa attttgtggc ggacattttt acggggaccg agatcattga gatacagaca
     2221 cgctcctttc aggttatgcg gagaaaactg gatgcgttct taaaaatcta tccggtcacg
     2281 atcgtctatc cgatcccgca tgtcaaatgg ctttcgtgga tcgatgagga gagtggcgag
     2341 atgtcaccga agcgcaagtc ccccaaaaaa ggaaatccgt atgtggcatt taaagaattg
     2401 tataaaatac gtccgttttt aaaaaatgaa aacttaagat ttcggtttgc actgatcgat
     2461 atggaggagt accgtctgtt aaacggctgg agcaaagata aaaagaaagg cagtgagcgc
     2521 tatgaccgga tcccggtgca gtttgtggag gaagtctgta ttgagagacg ggaagattat
     2581 atgcagttta tcccatttga cctgccggaa ccttttacta cgaaagattt ttcaaaatct
     2641 gcaaaaattc cgttgtcgct tgcacagact gtgcttctga ttctgacgga tttagaaatc
     2701 gtggacagag tgggaaaaca ggggaatagt tacctgtata aagtctgtga gatataagaa
     2761 aaagggtatc tggattttaa tagttactca cgatcagtct gcgccggaac acggaatcca
     2821 tatgatcgag tgtatgtctt gcctgggaat agcggttgcg gttggtatgg atgacataaa
     2881 actggtgtgc accccggtat ttttcgcgca gaaaaaatgg tatcttaata aaactccgca
     2941 taaatggaat ctgattttca atcaataact gtgccgcctg atcactgatc cgctcattgg
     3001 ttgtgcggca taactctata tctttgtcga gatgttttgt atcttttcct aatataagtg
     3061 cttttcccat agtttcttcc cctttttcaa aaaactatca tatacgataa cttttgtcaa
     3121 acatactttt atttttgcag aaattgtggt atgttattaa agttagacgg aaaagcttgt
     3181 cttaaaggat tagaaaggta attataatta tgaagaaaaa agtagtagta ttaatgcttt
     3241 gtacgatgat ggcagtcact gcactcggat gcggcgggaa gaagaatgat accgcagagg
     3301 ggacagaggc tgcagaatca gtaaacggca cggaaacagc agaaggaaca gaaacagtgg
     3361 aatatgagag tccttcttat gatctggatc cttccgatta tgtgacactc tgtgattaca
     3421 gcaaggttcc ggttacgatc acaggcgatt atgatgtgga tgaccaggat gcaaaagatt
     3481 attttgagca gatgttttct tattacggac cgttctacgt tgcagatgat accaaaacaa
     3541 ccgttggaga tggtgatatc gtaaacgtgg actatgttgg aaaattagac ggagtggcat
     3601 ttgataatgg aagtgccgag gatcagaata tcgatgtgga caataactgt tccgcaggaa
     3661 gccagtcaag ctcctttatt gacggcttta cagatgatct gaaaggtgca tctgtcggtg
     3721 atgttattga cagcgatgtg acattcccgg ataactatgg caatgcagac cttgccggaa
     3781 aacaggttgt attcacattt accgtcaact caatccagaa agagatgaca ctcgatgatg
     3841 tggatgacga ttttgcgcag aaacagtttc aggctgacac agtagatgat atgtatgcac
     3901 agattaaatc attccttgaa aatcaggcca gcagcaataa ggacagtgac acttacacag
     3961 cagtgcagga gtacctgtta gaaaattgta aagtggatat cccggaagat tatctgacag
     4021 cccgtgtcaa tgattatgag aaacagtatg tacagaatta ctgtgatggg gatgcatcca
     4081 aacttgagga ttacgtcagc agccagtaca acatgacact tgatgaggtg cgtcaggagt
     4141 ggaaatcagg catggagaaa aatatttcca tggagtttat cacaggtgcg atcgcagcaa
     4201 aagagggcac cgagcttgac gaggacggat tttcttctta tgtgcagact ctgatgagca
     4261 ataacagtct gtcatctgaa gacgatttat ataagaacta tggctacggt gatgcagctt
     4321 atggtgaaaa atatttaaga caggtctatg ttgataatct tgcattgcag tctgtcaaag
     4381 ataatgcgga tgtgactgtg gaagctccgg cggagacaga gagtactgag ggcacagaga
     4441 gtgcagaacc gcaggaagct gtcgacgctg ccgagacaga aacagcaaat taatcaaata
     4501 aatatcccaa aagaagacca aagagatggg gattggagga ttcaattatg gatatggtaa
     4561 atgtaaggga tttattccgg aaacaggaag aatatgtgga tcagaccgtg acgatcggtg
     4621 gatgggtgcg gagcatccgt aattccaaaa attttggatt tatcgtggtg aacgacggaa
     4681 catttttcga accggttcag gtcgtatatt ccaatgtttt agagaacttt gatgatgttg
     4741 aaaagttaaa tgtcggtgca gcgatcatcg tgacaggtaa gcttgttgca acacctggaa
     4801 ccaagcagcc gtttgaaatc caggcagaga aaatcgagat cgagggtgtt tccacaccgg
     4861 attatccgct gcagaaaaag aaacacagtt ttgagtattt aagaacgatc tcccatttaa
     4921 gaccaagaac aaacacgttt gaggcagttt tccgtgtgcg ttccctgatt gcatatgcaa
     4981 ttcataaatt tttccaggag agagattttg tttatgtaca cacaccactg atcacaggaa
     5041 gtgactgtga aggtgcggga gaaatgttcc aggtaacgac actggatatg aacaatcttc
     5101 cgaaaaatcc ggatggaacg gtagattata cgaaggattt ctttaataag ccgaccaatc
     5161 ttaccgtaag tggacagtta aacggtgaga catatgcgat ggcatttaag aacatctata
     5221 catttggccc gaccttccgt gcagaaaatt ccaacacgac cagacatgca gcagagttct
     5281 ggatgatcga gccggagatc gcatttgcag atctggaaga tgacatgatc ttagccgaga
     5341 gcatgttaaa atacatcatc aactatgtac ttgagaatgc accggaagag atggcatttt
     5401 tcaacaactt cattgacaaa ggactcttag agcgcttgca gcatgtggca aattccgatt
     5461 ttgcccgcgt gacatacaca gaggcagttg agatcttaga gaaacacaat gacaagtttg
     5521 aatataaagt ttcctgggga actgatcttc agacggagca tgagcgttat ctgaccgagg
     5581 agatcttcaa acgtccggta ttcgtaaccg attacccgaa ggagatcaag gcattctaca
     5641 tgaagatgaa tgatgacgga aagaccgtag cagccgttga ctgtctggta cctggtatcg
     5701 gtgagatcat cggaggaagc cagagagagg atgattacga taaacttctt gcaagaatca
     5761 atgaactcgg cttaaaagaa gaagattatc agttttatct ggatctccgc aaatatggtt
     5821 ctgcaagaca tgcaggattc ggactcggtt tcgagcgctg cgttatgtac ttgacaggaa
     5881 tgtctaacat ccgtgatgtt attccgttcc caagaaccgt aaataactgc gaattataaa
     5941 aaagaataga gttacagagg actgccgccc ggatgaataa gattctgcgg gcggcagttt
     6001 tttgatatcc gaatcttcat aggaaaatgc gttctgcaaa tttgtgtaaa cctcccaaaa
     6061 acctgcaaaa attgagaaaa aatgtagcat aaatataatt gacataatgt ataataagta
     6121 gtagtatcaa aatacaaaag atatagtaac aaatactaca tgtaaaaata ataaatacta
     6181 ttttgctaaa aggaggtcac attatgttac agatagggat tcgtgaaccg ggaagcgcca
     6241 ttacacattt tatagctatg atgatggcaa tatttgccac atcgccgttg ttagtcaagg
     6301 ctgcgctgaa tggaaatcat acaacgattc tggcaatggc cgtgtttatg ggaagcatgg
     6361 tgctgcttta tggtgcaagt acggtgtacc attcgcttgt tgtccgggat aaaattttaa
     6421 agatattccg caaactcgac catatgatga tatttgtcct gattgccgga tcttatacgc
     6481 cggtatgtct gatcgtactt ggcgggaagt cgggttatac gctgcttgcg gcagtgtggg
     6541 gcattgcggc ggcaggaatg ctgataaaag tgctctggat caactgcccg aagtggtttt
     6601 catccgtgat ctatatcgca atgggatggg tgtgtctgtt tgtattccgg gaactgttag
     6661 ccactctttc ccaggcagca tttttgtggc tgcttgcagg cggtctgatc tatactgtcg
     6721 gcggtgtgat ctatgcatta aaactgccgg tgttcaacgc gaagcacagt cagtttggct
     6781 cccatgaagt atttcatctg tttgtcatgg ctggaagcat ctgccatttt gtattcatgt
     6841 atcagtatgt agcgtgaaaa ataaaacgat tgccggatag attttatgga aaagttaggt
     6901 tataatgtaa cagcaatgaa aaatgagcag tgacaggcag atgagaaatg aaatgcctgt
     6961 atgaagagga gacagatatg agatatacgt tggaaaatga aaatttaaaa gtggagattg
     7021 actcatttgg agcagagatc aaatctgtaa aaagaaaatc agataacttt gaatatatgt
     7081 ggtgtggtga taaaaagtac tggggcagaa catcccctgt attatttccg tttgtcggtg
     7141 cgccgaaaaa caaagaatac cgttatgacg gaaaaactta tacgatggga cagcacggat
     7201 ttgcaagaga tatggagttt acattagagg cacagacgga agagaacatc tcatttgtac
     7261 tgaccgatac tgcggaaacc tgtgaaaaat atccatttca ttttgcgctg cacattggtt
     7321 atgaattgtg caaaaacgag gtgaaagtaa actggactgt ggaaaacacc gacacaaaag
     7381 aattatattt ttccatcggt gcacatccgg cattcaactg cccggttcac ggagaggaaa
     7441 ataaaaccgg atatggtctc aaatttggcg acctggcaga tactattcat catcatggaa
     7501 acacaccgga cggtatggcg gtgatggagg ataaagtcct ggcactgaaa gatggctgtg
     7561 tgacatttac ggaaggattc tttgatgagt gcacttacat ggtcgaagga aaacagaccg
     7621 gagaggtttc cctgcttgac cgtgaaggca tcccgtatgt aaccgtaaaa tttgacaccc
     7681 cgctgtttgc agtatggtca ccggaaggaa aaaatgcacc tttcgtctgc attgaaccat
     7741 ggtacggaag atgcgatgcc acagatttta ccggcacatt gcagcagcgc gactacgaaa
     7801 acatgctgcc gcagggcgga acattcaagg cagcttatag tattgcatat ctgtaagata
     7861 gagtcagcaa aaggtggatc ataaaaataa aaaacgcaaa agcatgtaaa aagagcatag
     7921 cttttgcgtt tttttcatat agtgaaacag aatcgaaaac ctgtggagtg gtcaatgaat
     7981 atacagtcaa aaatgaaaac aagagatgca aaaaacaatc cggtcactgc ggtattggtg
     8041 tccgtgctgg tcatgttcct tttaagctgc ctgttcctgt tactgttggc tgcactgtta
     8101 tataagtttg atctgagtga atcggcagta aaggtgggaa tcgttgtcat ttatatcgtc
     8161 tccggagtga tcggtggatt tttcatggga aagatcatga aaacacagaa atttttatgg
     8221 ggatttgcag cgggagccat ttatttttgc attttatttc tgatatcagt gctggttaaa
     8281 cagggagtct ccatggaact gccgaaagtg gcgacaacat ttattctatg tgcggcatcc
     8341 gggatggcgg gcggaatgat aagttagtgg ttactgtcag ggtgccaatt agcatataga
     8401 caggacttgc gcagaatatc agcggcgtgc tatactcaaa gaaaatgtgc atgaatgaaa
     8461 aaaattatca atgtttcatg cagaaaaaga tacgcacgag gaggaagaca tggaaagaca
     8521 gaagagacag ggagcagagt acgagtttta cggaaaactc ccgctgaaaa aggcaatccc
     8581 gctgggatta cagcatgtgc tggcaatgtt tgtgggaaac ctgacaccga tcctgatcat
     8641 ctcaggggca tgtggtattg caggtgagga gttcggcagt ctgcaggtcg atctgctgca
     8701 gaatgcgatg ctgatcgccg ggatcgtgac actgatccag ttatttgcga tcggaccggt
     8761 tggtggaaag gtaccgatca tcatgggaac gagttccgga tttatcggtg tgtttaacag
     8821 tgtggttcag gtaatgggag gaggaatcct tgcatatgga gccattatgt gtgcatccgt
     8881 cattggtggt ctgtttgagg gaatccttgg atttctgtta aagccgctcc gcagattttt
     8941 ccctgcggtt gtaacgggaa ccgttgtact gtcgatcgga ttgtcactga tcgcggtcgg
     9001 cgtcaattct tttggcggcg gcaatacggc aaacgacttt ggttcagtag aaaatttact
     9061 gctcggagca gctgttttac tgatcattgt agcagtgaaa cactggatga aaggtatggc
     9121 gagtgcatca tcgatcctga tcggtattgt ggcaggctat atcattgctg cgatcatggg
     9181 actggtactg ccgacaacag cagtcaatgc ggatggtgtg gaatacacaa aagcctgggt
     9241 gttaaactgg gataaggttg caaatgcagc ctggttttcc gttccgaaat taatgccggt
     9301 caaactggta tttgactgga gagcaatcat tccggttctg atcatgtttg ttgttaccgc
     9361 ggttgaaaca gtcggagata tctccggtgt tatggaaggt ggaatgggca gagaagctac
     9421 cgacaaagaa ctttccggcg gtgtcatctg tgatggaatc ggttcttcgc ttgcagcact
     9481 ttttggtgtt ctgccgaata cttctttcag tcagaatgta ggacttgtca caatgacgaa
     9541 aatcgtaaac cgtatggcgc ttgcatctgg agccgtattc ctgattttat gtggtttatt
     9601 cccgaaactt gcagcactga tttcaatcat gccgcagagt gtacttggag gagctgccgt
     9661 tatgatgttt tcatccatcg tgatcagcgg aatccagctt attaccaaag aaccgatgac
     9721 gatgcgcaat atcacgatcg tctccgtcgc attgggactt ggctatggaa tcggatccag
     9781 cagcggcatc cttgcacatc tgccgcaggg catccagctg atctttggcg gttccggtat
     9841 tgttccggca gccattgtgg cgatcatctt taatattatc ctgccgaagg atgcggaata
     9901 aaaaaaactt cccatatgaa aaaagttatg ttatactgta taagttaaca gaactccgcg
     9961 cgaaagcgaa taaatacata gtattacggg gagcgggcaa atggcgtatc ccatgtgtgc
    10021 ggaaattaca aaaaaggaga gaagcatcat gaaacatgta aagacattaa ataccaagag
    10081 attacagaac acaatcaaaa aaggcggctg cggcgagtgc cagacatcct gccagtctgc
    10141 atgcaaaaca tcctgtacag taggaaacca gagctgcgag cacaaataag atttgagctg
    10201 gtacagccgg gcatgcatag catggtaaaa attgtgcata tgagtgccgg atatgccatc
    10261 atggcatcat acaaaatgac tgtgtgatac aacgatgaaa atcatacggt cggatataag
    10321 tgaaatctgc aaacgaccgt tcgcatagcg tgcggtcatt tgtacgtttt atcggcaaca
    10381 ttaaaatgcc gtaatacttg aaaaaaatat attgatttgc agaaaacttt aaatgttttg
    10441 ctgtaaaatc agatagaaag agaggaaata ttatagtggt tcatcagtat aagaacaacg
    10501 gctatgatat tgttttagat gtaaacagcg gagcgattca tgtggtggat gacgtgactt
    10561 atgatgtcat tgagatgttc gatcagagcc agccggaatc gtatgcaagg gatgagatcg
    10621 tatctgcact gtccggaaaa tacggcaaag aggaagtgga ggaagcaatc gatgaagtcc
    10681 agacattgat cgatgaggag tcacttttta caaaggacac ttacgaaaac tatatcatgg
    10741 atttcaaaaa acgcccgacg gttgtcaagg cactctgcct gcatatagca catgactgca
    10801 acctggcatg tcagtactgc tttgctgagg agggagagta ccatggaaga agggcactga
    10861 tgtcctttga agttggaaag aaagcactgg atttcttaat tgccaattca ggtaacagac
    10921 gaaatcttga ggtggatttc tttggcggcg agccgcttat gaactggcag gtcgtaaaag
    10981 acttagttgc ctatggaaga gagcaggaaa agctgcatgg caagaatttc cgttttacac
    11041 tgaccacaaa tggtgtgctt ttaaatgacg agatcatgga attctgtaat aaagagatgg
    11101 caaatgtggt cttaagtatc gatggaagaa aggaagttca tgataagatg cgtccgttcc
    11161 gcaaaggggc aggaagttat gatctgatcg ttccaaagtt ccagaaattt gcagagagca
    11221 gacatcagga caaatattat gtgcgtggta cattcacaca ctacaatcct gattttgcag
    11281 cagatgtact tcatcttgcg gatcttggtt tcaaacagat ctccgtggag ccggtagttg
    11341 cagaaccgag tgaaccgtat gcgatcacag aggaagatct tccacagctg tttgaggaat
    11401 atgacaaact tgcagcggag atggtaagac gtcacaaaga gggagatgat tttaatttct
    11461 tccattttat gatcgatctt gagggcggtc catgtgtggc aaaacgtctg tccggctgtg
    11521 gttcaggaac cgagtacctt gcagtgacac catggggaga tttttatcca tgtcaccagt
    11581 ttgtcggcaa tgaaaagttt ttacttggca atgtggatga aggtataaaa aatacagaga
    11641 tccgtgatga gtttaagtgc tgtaatgtct atgcaaaaga aaaatgcaga aaatgtttcg
    11701 caagattcta ctgcagcggc ggatgtgcag caaatgcgta taatttcagc ggtgacatct
    11761 gtggggcata tgatatcgga tgtgaattgc agaaaaaacg tattgagtgc gcgatcatga
    11821 ttaaggctgc cgaggccgat tgtgaataaa taagaaacag gaaggaaaaa gaaaatgaaa
    11881 aagagtaaag cagcagtcat attagttgcg attctcgctg catttgcggg acttgcctat
    11941 tatgcatcta ttattctttc atcgaccggt attggggaag aaatgagtat tccgcttgga
    12001 cttgatctgt ccggtggtgt atcgatcacc tatcaggtca tggatgaaaa tccgagtgca
    12061 gaggatatga gtgatacgat ttacaaactc cagaagcgtg tggaaagtta cagtacagag
    12121 gcatccgtat atcaggttgg agatgatcgt atcgccgttg agatcccggg tgttacggac
    12181 gcaagcaaga ttttggaaga acttggtaat ccgggttcct tagagttcca gctttcagat
    12241 ggtaccgtat ttatgacggg tgaccaggtg gcagatgcac aggctgcaac aaccacagat
    12301 cagtatggaa acaagcagta tgtggtacag cttacactga cagatgaggg agcaaagact
    12361 ttcggagaag ttacttctga aaacgtcgga aaagcacttc caatcgtata cgatggagaa
    12421 gttatcagtt atccgactgt tcaggaggca attaccggag gtactgcaca gatttccggt
    12481 cagagcacct ttgaagaggc acagacttta gcaacacaga tcagaatcgg ttctctttcc
    12541 ctgcagttat cagagttaga gtccagtgtg gtaggagcac agcttggaag ccaggcaatc
    12601 tcctccagtt taaaagcggc agcaatcggt cttgtgatcg taatggtatt tatgatcatt
    12661 gtatatgcag ttccgggtgt cgcagcagct ttagcacttg caatttatac agcacttgtg
    12721 attgcaactt tatacttatt cgagatcaca ttaacattac ctggtattgc cggtattatc
    12781 ttaagtattg gtatggcagt ggatgcgaac gttatcatct ttgcacgtat ccgtgaagaa
    12841 attgcatcag gaaaatccgt gattactgca atgaagaatg gtttccacaa agcgatgtct
    12901 gcaatcttag atggtaatat cacaacattg attgcagcga ttgttcttat gggattaggt
    12961 tccggtactg taaaaggatt tgcatataca ctgatgatcg gtattatcct ttccatgttt
    13021 acagcacttg ttgtcacaag atggatcctt tattctttct actggttagg aatgagagat
    13081 gaaaaattct acggacgtgc aaaagagaga aagacgatca atttcctgca gaagagatat
    13141 gtattctttg caatttctat tgcagttata gctgccggat ttatcggtat gggagtacat
    13201 aaggcatctg gtcagaactc cctgaattat ggacttgact tcatgggagg aacttccact
    13261 actgctgatt tcggcaaaga atatacgatc gaagatattg aaaatgatat tatcccggtt
    13321 gtaaaagaag taactggaga cagcaatatt caggcaaaca aagtagaggg aacaactcag
    13381 attacgatca agacacgtac tttatccaaa gaagagcgtg atgatctgaa taataagctg
    13441 gcagacagtt ttgatgtaga tgaatccacc attacattcc agagtatcag ttccacgatc
    13501 agtggtgaga tgcgtgcgga tgcagtcaag gcggttatta tctcaacaat ctgtatgctg
    13561 atctatatct ggttccgttt taaagatatc cgtttcggtg ccagtgcgat cattgccctg
    13621 atccacgacg tactggttgt acttaccgta tatgcgctga tgcgtatttc agtcggcaat
    13681 acatttatcg catgtatgct gacgatcatt ggttattctg tcaacgatac gatcgttatc
    13741 tttgaccgta tccgtgagaa ccttgcatta aagcatggta aacagacaag ggaagatctg
    13801 atggaagtag caaaccgaag cctgacacag accttatcac gaagcatcaa cacatccata
    13861 acaacattta ttatggtatt tatgctgttc cttcttggtg tagcaagtat tcgtgaattt
    13921 gcactgccgc tgatggcagg tatgatctgc ggtgcatatt catctatctg cattgcaacc
    13981 gagttgtggt atgtgatgaa agttcatctt ggtaaaaata aaataacaga ataagatctg
    14041 ttgaagaaaa gtgaaagtcc tggcagttat ttgccgggac ttttaagatt cataggaaat
    14101 tacgtcctat gaatcttaaa gccctccggg cgggatcaca ctgcgtcgga gatgaattat
    14161 gtcgcgcagg cggtgaatcc tgtagaacag gattctattt tagaaaaaag gagaaacata
    14221 tggatacgat cgcagcttat ctgatctttt taaatctggt gggcttcctt attatgggag
    14281 aggataaaag aagggcgaaa atgcatcgat ggcggatctc agaaagaatg ctttttttag
    14341 tcagcatttt aggcggcagt atcggaacgt gggcgggaat gtatgtgttc cgccacaaga
    14401 cgagacactg gtattttgtt ataggaatac cactgatcct cattttacag atcgcaggtg
    14461 ccatctggct ttatcgtcag ggcttatatc atttataata atttgatata actattctgg
    14521 catttggaat tgccaaaaaa aggaaagtca tatataatga taaacatagc aaaagacaag
    14581 tgtttttcgt agaaagacac attgatcaaa cagcaaagaa agggagaatt acggattatg
    14641 tatacactgg aagatattca ggcagttgat atggaagtgg caaatgccat caccgatgaa
    14701 tttgaacgtc agaacagtca tattgagctg attgcatccg aaaactgggt aagcaaggca
    14761 gtgatgtcgg cgatgggcag tgttcttaca aataaatatg cagaaggtta tccggggaaa
    14821 agatattacg gcggatgtga gtgtgtggat gttgtagagg aacttgcaag agagcgtgcg
    14881 aaagagctgt ttggctgtga gtatgcgaac gtacagccac attcaggtgc acaggcgaat
    14941 atggctgtac agtttgccat cttaaaaccg ggtgacacgg tcatgggaat gaacttagat
    15001 cacggcggac atttgacaca cggaagccct gtaaactttt ccggtactta ttttcacatt
    15061 gtaccttacg gtgtcaatga cgagggattt attgattatg acaaagtaga agagatcgcg
    15121 atggagtgca agccgaagat gatcatcgca ggtgcaagtg cttatgcgag aaccattgat
    15181 ttcaagagat tccgtgagat cgcagatgca tgcggagcag ttctgatggt cgatatggca
    15241 catatcgcag gacttgtcgc tgcaggactt catccaagcc caatcccgta tgcacacgtt
    15301 gtcacaacca caacacacaa gacactgcgt ggaccgcgtg gaggcatgat cttatccagt
    15361 caggaaatcg cagacaaata taactttaac aaagctattt tccctggaat ccagggcgga
    15421 cctttgatgc atgtgattgc tgcgaaggca gtctgcttta aagaggcact tcagccggag
    15481 tttaaagtat accagcagaa tatcattgac aatgcacagg cactctgcaa gggactgtta
    15541 agccgtgata ttaaaatcgt atccggcggt acagacaatc acctgatgct tgttgatctg
    15601 acaaattatg atcagaccgg aaaggcagtg gagaaacttc tcgattctgt caatattacc
    15661 tgcaacaaga atacgatccc gaacgatccg aaatccccat tcgtaacaag cggtgtacgt
    15721 cttggaacgc cggcagttac ttcccgtgga ctaaacacag aggatatgga tcagattgca
    15781 gaggcaatcg ccatgatgat caaggagggt gaaccggcag ctgataaagc gtgtgcaatc
    15841 gtaaaatcgc tgacagagaa atatccgctg gagagataaa agagaataga atataattta
    15901 ataatgaata aaaaatgagg aacctgtttc gtgacaggtt cctcgttttt tgtgcttttt
    15961 gagtttgtta ttttacatca tctgcaatac ggtacagtgt gtacgaggta gaaatcgtat
    16021 ttttattttt atcgagatat gtgattttca cgattgtcgg tgccataata tcaccatcac
    16081 ggctgtatga ctcataagag taagtaccat atgcgtaaga gtagtcatgt ccgtaatagt
    16141 atccataatg tcctaactgg atactctttc cattttttac cttttttgtt atctcggagt
    16201 ttgaataagt ggttgaatag gaagaatttg tttttgcaac tggcttgctg taagtagagt
    16261 attcgatctt ctttaattta taacccttgt tcattttgac attgactttg acagaatttt
    16321 tattgtagac tgcctttgcg taatcatatt ctttgttgtt aaaagttaca ctcttaaaag
    16381 gactattgtt agagaatgtc ggctcggtta cattgacttt gacagtaaat tttttaatct
    16441 ttttattctg tgcattatat acatcaaaag atactgtgta tttaccggtt ttcttggcat
    16501 agacaccaac gtatccggaa ttactggagc tggaaagtga aagtcttgtt actttggctt
    16561 tcaggttttt gctcgatgtt ttgatatttt tgatgttttt tccgtttgta ccgagctgta
    16621 cggagatagc cgaatcattg accatcggat aatttttgta ataagaaaca tctacagcct
    16681 ttggggcgct tggacctgtt gcagcagata ccggcgcaga agggatcagt aataatccgg
    16741 cgcacaggca aagtgtaaga acagcgcaag taatttgctt aaataatttc atatcagata
    16801 tcctcctgtt ggattatttt gcaagacggg aaatggaata aatactctca cattcctgct
    16861 tggtatattt gtcgatataa gtaatagtga tcttggtacg cgcagcaagt gaggtagaat
    16921 agtttctgcc gctggaatat gaattatcaa atatatatgc gtactcgcca agctttaagg
    16981 tgctgttgtt tttcattgtt tttacaactt ctttacctgc cttattgtaa gtggtgacag
    17041 tgattttttt cagcgtgtaa cctttgttca ttttaacaga taatttgccg gattttttgc
    17101 tcgtaagggc ataattaact tctttacctg caaatttgac agatttgact ggcaggtcat
    17161 tttttacata tactgttact ttacccgaag aaagtttgtt tcctgattta tcgcagatat
    17221 tataggtgac tttgtattta ccggtttttt tggcatagag gccgatagac gcaaaggtat
    17281 ccgtgtatgt atcgtctgaa ctggtagtat aatagtgggt gttttttgca atcagatttt
    17341 tactgctggt tttgatgttt ttgatataac atactttggc ttttggcaga ttgacataga
    17401 ttgcagaact gtcgaaagaa ttactggaca tgcgaagtac agtggtggtc ggtttgttcc
    17461 tgacggctgc ggataccgtt gactgcggct gcagtaaaag catcccggca cagagacaga
    17521 aagctaaaaa taagctgact gttcgtttga aaattttcat aagtgaatcc tccttgttta
    17581 taaatatttt atagatgtta caaaaacatt acaatatgaa gggaaatttt atacaatcat
    17641 aaattaaaaa ataaataagg gaattttaag aaaatttata gcattatatc aggtaatttt
    17701 gatatgccca aacttgtatt ttatgtcagg ttattttata attgcataca atagattgtg
    17761 tattttatga gcggggggag agaagaaaaa acagaaaccc agcctgcctg taaaatatgc
    17821 agaaacgagg aatatatgaa aaaacagagt aaaggagttc cgacaaaccg tgatatccgt
    17881 tgggacagac ttgataatac agcacacctt tttccggtca ttgccgggga gagcatgagc
    17941 aatgtgtaca ggatcagtgt tacactgaaa gaggagatca atccggaatt actgcagagg
    18001 gcacttgata tggtgcttcc gaagtttgac gggtttaact taagactgcg gcagggggtg
    18061 ttctggtatt attttgagga aaacggaaaa gcggcgccaa aggttcgcat ggagaacaat
    18121 tttccatgca gatatatcca gcagaataaa aaccgcagtt atatgttccg tgtgacctat
    18181 tataaatgca ggatcaatct ggaagtattc catgttttga cggatggaat gggaggaatt
    18241 aatttcttaa aagagctgac ttaccagtat ctgcgtctgg cacataaaga cctgcaggaa
    18301 aaactgggag attcattaag tgttgatacg tctttgaacc gggaagacag tttcttaaaa
    18361 aattacaaaa aaagttccgc aaaaggatac cagacaaaaa aggcatatct gatccgtgga
    18421 gaaaagttaa gaccgggcga gttcggcgtg atgcacggtt atatgaaaat accggagttg
    18481 aaaagggtct gtcatgcgat gggaatcagt atcaacgaat atctggtaag tgtgtacatc
    18541 tggagcgttt atacagaatg tctgcacggc atgccgtcaa agtgtccgat ccgtgttgcg
    18601 gtgccggtta atctgcggcc gtattttaat tctattacca cgaaaaactt ttttgtcatg
    18661 gtgtccgcag aatttcatcc gaccaaagag acctatacgt ttgcagaggt ggctgcaatc
    18721 gtgaaggaaa gcctgcgaag ccagatcaac cgggaaaatc ttgaaaagct gttttcctat
    18781 aacgtttcca atgaaaaact gctgattgca agagttgtgc cgcttttcct gaaaaacctt
    18841 gcaatgaagt atgtatatac aacttctgca cttgccaata ctgcgacgat cacaaatatc
    18901 ggcaatattt ccgtgacaga agagtaccgc ccttatgtgg aaatgtttca tgcatttctt
    18961 gccatgtcaa aggggcagca tctgaaagga acgatctgct cttacgggga tacacttgta
    19021 ttcagtttca gttatgatct tgtcgatgcg tctgtgcagc gtggattttt ccggaaaata
    19081 gcctcggacg ggattgcggt agaaataaag agtaatggag taaattatga gtaaatgcag
    19141 aaattgtaat gtggagatat cagatgaaac agagcgctgt ccactctgcg gatccgtgtt
    19201 agaatacaca ggtgaagtgg agaatatgta cccggatgtg agagtgcaca cccggaaaat
    19261 gacaatgatc agtaaaatct atctgttttg tgcacttttg gttgaggtgc tgctcattta
    19321 tatcaatgtg gtcaccgagt cacagattgc atggagtgcg atcacggggc ttggattctt
    19381 ttacggatat atgctgatcc gttttgcaat tcttggaaag acaggttacc gcgccaaaat
    19441 cacggtactc acgctgatgg cgatactgat cgtgatcgca atcgattttc tggtcggcta
    19501 ccgcggatgg tctgtcaatt atgcattgcc gtcggcgatc attttagtcg atgttggtat
    19561 tatcatctgt atgatcgtaa accgcagaaa ctggcagagc tatatgatgt ggcagatttt
    19621 tatgatctta tgcagcattg ttccggtaat actgattttt accggtatcg tgacggcaca
    19681 gctttttgca ctgatcgcat ttgcgttttc cctgtttctg tttcttggaa cactgatcat
    19741 cggagaccgc agggcaaggg tggaactgaa acgaagattt catgtccgct gagttatatt
    19801 tagaataaaa aaaacaggag caatcggatg agagagagcg aagcgagcat caggggaaga
    19861 gtcatgaggg acttgatcgc ccatgtgaca aatgatcacc tgattgggaa aaagataaaa
    19921 aatggagaac tgaggaaaaa aatcggggat tcggagccgc cgtggaaatg tccggactgt
    19981 ttttcattag atgtgatcga gatggataat ttctccatgg agtatttaca ggcaaaagaa
    20041 aatccgaata cggaaaaagt aatcttacag cttcacgggg gcggatatgt cggagcgatg
    20101 cggaatgcat accgtatgtt tgccggactt tactgtgaag tcagccatgg aatgagtgtt
    20161 ctgacacccg attaccgtgt ggcaccggaa catccgtatc cggcggcttt agaagatgcc
    20221 tatgccgcat actgttatct gttggaacag gggtggtttt ccgagcagat catcatcgca
    20281 ggagattccg caggaggcgg tcttgcgatg gcattatgcc attatctgaa agatcacgga
    20341 aagcagcttc cgtgtgggat cgtagccatg tcaccgtgga cagaccttgc ggcgagcggg
    20401 gaatcttacg agacaaactt tgagcgcgac ccgttatttg gaaaaacaag ggacagcctt
    20461 atttataata aagattatat tggggataac gacccgtata atgcttatat ttcgccttta
    20521 tatggggatt tcaggggatt tccgccgatg ctgatacagg ttggttccta tgagatgctg
    20581 ctctcggatt ctgtggatgt ggctgcaaaa gccagagaac agggagtaaa agtaagaatc
    20641 agtatttatg aaggaatgtt ccacatcttt cagatggcag caaaaatgct gccggaatct
    20701 aaaagagcgt gggttgagat cggtaaattt attgatgttt tgctaaatga ctgacatcca
    20761 tatagacagg gataccgctt tcgtatttta ctggaacttc accgagtatg agaggtgaaa
    20821 ggtaatcgat cagtggctgt gtgacatcat tgcctgcatc gttgatccat tctctcggaa
    20881 ttgattttgc ctcgtttgca atgtggcgga tctcggcatg ctcataggcg atttcgtacg
    20941 gagcatcaga gatacggcgc attgttacca tggaagcggt aacaccttcc tcggagagag
    21001 caaccgcttt ctgaccgaga gtaaaagcct catcaagatc agtctttgaa gcaaggtgtg
    21061 cagcgcagcg ctgtaatacg ttgacttcca cggaacggac tttaacgcct agtttttctt
    21121 tgactaaaaa ttcaagtgtt tttccggctc cgcttaactg gctgtgacca aaggtgtcaa
    21181 cagaactttc ggaagcactg atatagttgc cggaagcatc gcggatacct tcggatacgg
    21241 caacgatcac gttattgcgc tcgaaaagca tacgctttac atccagtaaa aagtcctctt
    21301 tgtcaaatgg aacctccggg agatagatca gatgtggtgc tgtattataa ccgtttcttg
    21361 ccagtgcaga agcagcggtc agccatccgg catcacgtcc catgatttcc acgatcgtca
    21421 cacttttgac tgcatagata aatgtgtcat gtgcgatttc taaaagagaa gatgcgatat
    21481 attttgcagc agaaccgaat cctggtgtat ggtctgtctc acagagatca ttgtcgatgg
    21541 tctttggaat accgacaata cgcaccggac tgccgatttt tttgccatat tcggagagct
    21601 ttaagacggt gtccatagaa tcgttgccgc cgatataaaa gaaagcatca atatggtaag
    21661 tttcaaactg tttgaaaatg aatacatagg aagaatcatc atctaaataa tttggcagtt
    21721 tgtaacggca ggagccaaga tacattgccg gagtgacctt taagcggtcg agatattccg
    21781 aattctgctg cattaattca gaaagattcg tcagatcgtt gtttaaaata cctgtgattc
    21841 cgtttaagg
//
