LOCUS       c00020_gnlPro..        15030 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MCGGAMID_20.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:43:26
            Original ID  :: gnl|Prokka|MCGGAMID_20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15030
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15030
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1590:5030]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1591..5030
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15030
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15030
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(378..1331)
                     /locus_tag="ctg20_1"
                     /transl_table=11
                     /translation="MKTAIFSIGVFLISLFLGSCQPSETSCSVVDTGKTLDYKIGDKLL
                     FSYNYTTVYPASGVDSVYKRSGFIHPLKTLGGEVMTNCSPADHYHHFGLWYAWTKTTFE
                     GNEIDFWNLHKKQGTVRFRNFEHVSDNGFVATLDHVVYPDSPAEKVAMNERLEINIGTT
                     SLPGYYIDYHTTIRLASPSPITMEAYRYGGICIRTREDWNDQTAEMLTSEGLSRDEADG
                     SRARWCYYQGKAGNEKACILIVASPSNLNYPEPLRVWDKTVNKPAGDVMWNFSPTKQKA
                     FTLEPGKELSLSYRIYVLDKNINATTAEVLSDFERD"
     CDS             1591..2265
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_2"
                     /sec_met_domain="SucD_FumR (E-value: 2e-66, bitscore:
                     217.4, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLILFLVFHLCMNIAAVFSGEAYNVI
                     CGLLGSNWYALLGTLVLAAGVVVHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGVIVILFMVLHFTQFWYNMMFAELAGIHGDIHPQDGAAFINFYFQGNVVNTVLYL
                     IWFVALWFHLTHGFWSAIHTIGWNNTVWLSRWECISKWVATIICGLFAVITVIFYLNGV
                     GA"
     CDS             2304..4247
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.4; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 5e-59, bitscore:
                     194.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.2e-37,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERFAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAINARIAKLMNVKGKETVDSIHRKLGHI
                     MWEHVGMARDAEGLKEAIQMLKDLKKEFWSNVFIPGEANSLNVELDKALRLADFIEIGA
                     LMAHDALDRAESCGGHFRTEHQTEEGEAMRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             4275..5030
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_4"
                     /sec_met_domain="Fer2_3 (E-value: 2e-25, bitscore: 83.0,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6e-11, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.4e-05, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKGPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANAIPISKADADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFISAKLQD"
     CDS             5221..5379
                     /locus_tag="ctg20_5"
                     /transl_table=11
                     /translation="MKKTHCKYKVYLLNTQEFVITFYCKFATFCFKIDTVCGFTLLLYQ
                     QSIDSDT"
     CDS             complement(5352..6383)
                     /locus_tag="ctg20_6"
                     /transl_table=11
                     /translation="MKIGTIDLGERPVFLAPMEDVTDISFRLMCKRFGADMVYTEFVSA
                     DALIRSVNKTQQKLNVADEERPVAIQIYGRDVPTMVEAAQICEAAHPDILDINFGCPVK
                     RVAGKGAGAGMLRNIPLMLDITREVVKAVNIPVTVKTRLGWDADNRIIVDLAEQLQDCG
                     IAALSIHGRTRAQMYTGEADWTLIGEVKNNPRIQIPIIGNGDVTSAEICKQRFEQYGVD
                     AVMIGRGSIGRPWIFREVRHYLDTGETLPAESFSWYLNILKKQVEQSVERLDERRGILH
                     IRRHLAATPLFKGIADFKQTRVAMLRAETVEALFDILDSIPDKFHTGYGFQSDSQVSES
                     IDC"
     CDS             6764..8023
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_7"
                     /sec_met_domain="Peptidase_U32 (E-value: 2.8e-68, bitscore:
                     223.6, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LNEKDFEIMAPVGSYESLMAAIQGGADSIYFGIEGLNMRSRSSNN
                     FTTDDLRKIVALCREHGIKSYLTVNTVIYGEDLPLMREIIDAAKEAEVSAIIAADVAAM
                     NYANSIGQEVHLSTQLNISNAEALKFYARFADVVVLARELNLKQVHEIYRQIVDQQITG
                     PKGELIRIEMFAHGALCMAVSGKCYLSLHEMNASANRGACMQICRRAYSVKDKDSNIEL
                     DIENQYIMSPKDLKTIHFMNKMMDAGVRVFKIEGRARGPEYVRLVTECYKEAVRAYCNG
                     TFDEKKVAAWDERLRSVFNRGFWDGYYLGQRLGEWSSKYGSGATKKKVYVAKGIKYFDK
                     IGVAEFEMESGNLKVGDEILITGPTTGAVMQTIEEIRVDLKPVDETVKGERFSLKVNEK
                     IRPSDRLYKMEKVQLEKVFE"
     CDS             8023..8430
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_8"
                     /sec_met_domain="HBT (E-value: 3.9e-08, bitscore: 27.7,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 6.1e-09, bitscore: 30.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYIFKLTDKVRDYECDLQGVVNNSNYQHYMEHTRHEFLESLGE
                     NFGKMHEKGVDGFVSRVEIQYKTSLKSGDSYISCLNVYKKGVKLVFEQDIYRASDNALA
                     TKGIVESVIVENGKLTRGEYFDEMLKRIEHT"
     CDS             8427..9542
                     /locus_tag="ctg20_9"
                     /transl_table=11
                     /translation="MTDKRIYQIGLTMINGVGDILARHLLQALGEAEAVFTEKQQLLGR
                     IPGIGSNIAAEIKRPEILQRAEKELAFIEKNNISCYYLTDTDYPVRLRECPDAPILFYF
                     KGNTNLDATRIISIVGTRNATEYGRELTESLIKDLAKVIPDLLVVSGLAYGIDICAHRN
                     ALYNRLPTVAVLAHGLDRIYPSCHRNTAVEMLESGGLLTDFPSGTEPDRPNFLRRNRIV
                     AGISDCTIVVESAEKGGSLVTADIAFSYGRDVYSFPGRIGDSHSKGCNNLIRQNKAGLI
                     TSADDLLSALCWDIQAGATSVQTELFFAEAETFTSEQNPVLAIMRTRNEIHINELASVL
                     EIPVHQLSMLLFELEINGKVKALPGNLYKLS"
     CDS             complement(9793..10683)
                     /locus_tag="ctg20_10"
                     /transl_table=11
                     /translation="MLSFILVLLLGGFMPAGNLLASDKEQNPHYITVKNSRDLQAYFRY
                     APDRPIVISGHRGGMLDGYPENCIESFEKTLSYMESFFEIDPRLTKDGIIVLMHDETID
                     RTTTGKGKVSDYTYAELQQFNLVDRNGNVTAFKIPTLKECLEWSKGKTILNLDIKDVPL
                     EVMADFIETEKPVNVMYTVHNASQARYYLDRKPDAMFSCWCKNREEFDNYEKAGIPWKQ
                     VMAYVGPKMKPEQQPLYDALHRNGVMCMISVAPTHDRAKTETEKTAGYRSEISTRPDVI
                     ETDYPYLFQGLDLTK"
     CDS             11291..11653
                     /locus_tag="ctg20_11"
                     /transl_table=11
                     /translation="MERLTRQEEDVMRWIWQIEPCFIKDILAKYEEPKPPYTTLASIVK
                     NLERKKYVKAKRYGNTYEYRPLIPQEEYKRTFMGSVVNNYFENSYKEMVSFFAKEQKIS
                     TDELKEIIDMIEKGRE"
     CDS             11674..13410
                     /locus_tag="ctg20_12"
                     /transl_table=11
                     /translation="MTPEFAYFLKVNVAFILLYAFYRLFFYKDTFFKLRRTILLAFFGV
                     SLLYPLMNIQDWIREQGPIVEVIQMYSAILPETTITPGNVPQTNWHDLLLPGISYLYWS
                     GVIALSFRFLVQLSSILLLARRSEVTLIRNVRVHLLNKPAGPFSFFRLVFLHPDSHSEK
                     EIDEILVHECTHVSQWHSIDVIICELVCIICWVNPFVWLLKREVRHNLEYLADDTVLES
                     GYDSRSYQYHLLGLAHTNRSVTSLSNNFNMLHLKNRISMMNKKRSRSIGRTKYLIFIPV
                     VGALLILSNVDALARITDELTESTFADVLLPEAILPFPFVGDASPAEKREEYVLSEEGI
                     EAARRARNPVFTVVEVMPEFPGGQGALLKFLATNVRYPESAVKNGIEGRVSCSFVVGKD
                     GAISEAEVIRGVSPELNEEALRVINSMPVWSPGKQRGKVVNVKYTVPVTFRLSGGKKKT
                     SSRIVQRQIKEVDTSGRVFTVVQQMPEFPSGQASLLKYLATRIKYPAIAQENGIQGRVS
                     CSFVVDTDGSLKNIEVIRGIDPSLDREAVRVIREMPKWNPGVQNNMAVAVKYTVPVTFR
                     LQ"
     CDS             13444..14997
                     /locus_tag="ctg20_13"
                     /transl_table=11
                     /translation="MKCKFSLLLFLCVLSLWGQAQSLNLQELVNKKQFQEVVARADSLT
                     PADSADYATMSAIGQAYEGLLRYKEAYQCFSHCLKMDTNNVDALNAVARNAINFGRIAE
                     AKQCYRKVLGTDSMNFYANYQLARLYYQLGDYGRATEHYHILASIEGENPSILTGLADC
                     HIKRGTGPNTMIALSLYARALELNPENVRVASSLINTLLRMGDGQGALQVCDTALFYNP
                     DNSQIRQSKGMALYMTKDYKQADSVYTGLLADGDSSFLNLKYAGAARYMSGHALDGVEL
                     LEKAYEIDSTDVETVMLYGASLGKTYDRKRAYELFDLAETNMQPKKFLVNMLTTFRGDA
                     LERDGRWPEAEKLYYAAWKEDPTQLHFLYKISTQYWDVDPGLFQQEEKLQKTIFSRYTY
                     LTAYMKTDKSQKYLYNYRPFLEAVCEDAFFRNADEVTMLAPDGKKTKLAVADLRALVAQ
                     LPQMPEDERLRREKMQEHIKKAREKEKELRKSGAKLDTLALSKEEKEKARKMLKDADLE
                     "
ORIGIN
        1 ccttgcgacg agtcaatgac ttctcttttt tcatctttgt tgacttttat gaagtcaacc
       61 tatttcagga cgagacaatc gctcatctat ctgttttaaa tgaataaact ccaagcattt
      121 taaggtaaaa gtagggagac aattttatca acacccccat gtatccgccc ccgacacccg
      181 gatcttacgc tcttatagat ccgggtgtcg ggggcggata catgggggtg ttgggtaagt
      241 tttattacgt gtttttcatt gatttgtagc tgtatttaca taaaagagcc ttgtctttga
      301 tgatatagga gaacaagccc tttttccttt tcttgtttac cttgccctgc aaattgtcag
      361 tttgttttag tagaaattca atcacgttcg aaatcggaca gcacttctgc cgtagtagcg
      421 ttgatgttct tgtccaatac ataaatgcgg taagacaggc tcagttcttt accgggttcc
      481 aaggtgaatg ccttctgctt ggtcggtgag aaattccaca tgacgtcacc ggcaggcttg
      541 ttgacagttt tgtcccatac gcgtaaaggc tcaggatagt tcaggttgga aggggaggca
      601 acgattagga tacaggcctt ttcgtttccg gctttccctt ggtagtagca ccaacgggct
      661 ctcgaaccgt cagcttcgtc gcgggaaagg ccttccgagg tgagcatttc ggctgtctga
      721 tcgttccagt cttcgcgcgt acggatgcat atgccgccat aacggtaagc ttccatggtg
      781 atcgggctgg ggctggcgag gcggatagtg gtatgatagt cgatgtaata acctggtaag
      841 gatgttgtcc cgatgttgat ctccaggcgt tcgttcattg ctactttttc tgcgggagaa
      901 tcggggtaga ccacatggtc cagtgtcgca acaaaaccgt tgtcggatac gtgttcgaag
      961 ttgcggaagc gaactgttcc ttgttttttg tggagattcc agaagtcgat ctcgtttcct
     1021 tcgaacgtgg ttttcgtcca ggcataccac aaaccgaaat gatggtaatg gtcggcggga
     1081 gaacaattgg tcatcacttc gcctcccaat gtcttcaaag gatggatgaa accgctgcgt
     1141 ttatagaccg agtcaacgcc agaggctggg taaactgtgg tatagttgta agagaacaac
     1201 agtttatctc ctatcttata gtctaaggtt ttccccgtgt cgacgacgga acaggatgtt
     1261 tcggaaggct gacaagagcc taagaacaga gaaatcaaaa aaacaccaat agaaaaaata
     1321 gcagttttca taatatgaca attaaataat aatcagttat ccggcaagac cttgcctgta
     1381 tcggctacaa aaaaacgaaa ttttttcgtt tcgcacaatc cgtttgtgat atctgatgca
     1441 aataaaacca gccagcaagc agcgttctaa ttgatgaaat atttctttaa tcgtttgcgt
     1501 gatatgggga tttagcatac ctttgcacga taataaccat agattggagg aaatttctaa
     1561 atacaattaa ataacttaaa ttattatctt atgtggttac ttaattcttc tatcgggaag
     1621 aagctgataa tgagtatatc aggtcttttt ctcattctgt tcttggtgtt ccacttatgt
     1681 atgaacattg cggcagtatt ttctggtgaa gcgtataacg tgatttgcgg tttgctgggt
     1741 tctaactggt atgctttgct cggtacattg gtgttggctg caggtgtagt cgtgcacttc
     1801 gtgtatgcta ttatcttgac tctgcagaat cgtaaggctc gcggtaacga ccgttatgcc
     1861 atcaacgctc gtccgaaagg tgttgaatgg gcttctcaga acatgtttgt tttgggtgtg
     1921 atcgttatcc tgttcatggt tctgcacttt actcagttct ggtacaacat gatgtttgcc
     1981 gaactggcag gtattcatgg tgacattcat ccgcaggatg gtgcagcgtt tatcaatttc
     2041 tacttccagg gcaatgtcgt gaatacggtg ttgtatctga tctggttcgt tgctctgtgg
     2101 tttcacctga ctcacggttt ctggtctgcg attcacacaa ttggctggaa caataccgtt
     2161 tggttaagcc gttgggaatg tatctctaaa tgggttgcca ctattatttg tggcttattc
     2221 gctgttatca cagttatctt ctacctgaac ggtgtaggtg cttaatttcg gatattattt
     2281 tttcaatttg aaaataaaac attatgactc aaatagattc taaaattcct caaggcccgt
     2341 tggctgagaa gtggacaaat tataaaaatc accagaaatt ggtgaatccc gcaaacaaac
     2401 gtcgtttgga cataattgta gtaggtactg gtctggcggg tgcttctgct gctgcctctc
     2461 tggctgaaat gggattcaat gtattgaatt tctgtattca ggactctccc cgtcgtgcac
     2521 actctatcgc tgcacagggc ggtatcaatg cggcaaagaa ttatcagaat gatggtgact
     2581 cggtttatcg tctgttctac gatacaatca aaggtggtga ctaccgtgcc cgcgaagcaa
     2641 acgtctatcg tctggctgaa gtgtcaaact ctattatcga ccagtgcgta gcacagggtg
     2701 taccattcgc tcgcgaatat ggtggtctgt tggataaccg ttcattcggt ggtgctcagg
     2761 tatcccgtac gttctatgcc cgtggtcaga ccggacagca gctgctgttg ggtgcttact
     2821 ctgcattgag ccgtcagatt ggtttgggaa aggtgaagat gtacacacgc catgaaatgc
     2881 tggatgttgt gaaggttgac ggacgtgctc gcggtattat tgcccgtaat ttgattaccg
     2941 gtaagatcga acgttttgcc gctcacgcag tcgttgttgc gacaggtggt tatgtaaata
     3001 cattcttctt gtctactaac gcgatggcgt ctaacggttc tgctgcatgg cagtgctaca
     3061 agaaaggggc ttactttgct aatccttgta tggtgcagat ccacccgact tgtgtgccgg
     3121 tgaaaggtga cttccagtct aaactgactt tgatgtctga atcactgcgt aacgatggtc
     3181 gcatctgggt tccgaagaag ctggaagatg cgaaggcatt gcaggccgga acaaaaaagg
     3241 gaaaggatat tcctgaagca gatcgcgact actatctgga acgtcgttat ccggcattcg
     3301 gtaacttggt tcctcgtgat gtggcttcac gtgccgctaa agaacgttgt gatgccggtt
     3361 tcggtgtaaa tagcacgggc ttggctgtat tcctggattt ctccgacgct atcaaccgtc
     3421 tgggtaagga agtggttaaa cagaaatatg gtaacctgtt cgatatgtac gaagagatca
     3481 cgaacgatga tccgtacgaa actccgatga tgatttatcc tgcattgcac tactcaatgg
     3541 gtggtttgtg ggtagactat gaattgatga cttctattcc ggggctgttc gcaattggtg
     3601 aagccaactt ctctgaccat ggcgctaacc gtctgggtgc ttctgctttg atgcagggat
     3661 tggctgatgg ttactttgta ttgccttaca cgatccagaa ctatctgtct gaccagatcc
     3721 aggttccgcg ctttagcact gacctgcctg aatttgtgga agcagaaaag gctattaacg
     3781 cccgtatcgc gaagttgatg aacgtgaagg gtaaagaaac tgtcgattct atccaccgta
     3841 agctgggaca tatcatgtgg gaacacgtcg gtatggcacg cgacgcggaa ggcttgaaag
     3901 aagctatcca aatgttgaaa gacctgaaga aggaattctg gagcaatgta ttcattccgg
     3961 gtgaagcgaa cagcttgaac gtggaattgg acaaggcatt gcgtttggct gactttatcg
     4021 aaatcggtgc attgatggca cacgatgcgt tagaccgcgc agaatcttgt ggtggccact
     4081 tccgtacgga acatcagacc gaagaaggcg aagctatgcg tcatgacgat aagttcatgt
     4141 acgtctcttg ttgggaatac cagggtgaag acaaagaccc ggttatgctg aaggaagatt
     4201 tgaactatca gttcgttgtt cctcaaacac gtaactacaa gaagtaataa tcatcaatca
     4261 caaaaattag aatcatggat aaagatataa aggtaacact taaagtttgg cgtcagaaag
     4321 gtccgaaaga taaaggacag tttgagactt accaaatcga caaaatcaat cagagtgttt
     4381 ctttcttgga aatgttagac attttgaatg aacgtttggt tagcgaaggt aaagaaccta
     4441 tcgtattcga ccacgactgc cgtgaaggta tctgcggtat gtgttcattg tatgtaaacg
     4501 gacatccgca cggaccggca acaggtgcaa caacctgtca gctctatatg cgccgtttca
     4561 atgatggtga gacgattacg atcgagccgt ggcgttctgc cggtttcccg gtaatccgcg
     4621 acttgatggt agaccgttat gcttatgata agattatcca ggcaggtggt ttcgtttctg
     4681 taaacacagg tggggttcct gatgctaatg caattcctat ttctaaggct gatgcggatt
     4741 tggctatgga tgctgctgct tgtatcggct gcggtgcttg tgctgctgct tgtaagaacg
     4801 gttcagctat gctgttcgtc tctgcaaagg ttagccagct ggctcttttg cctcagggta
     4861 aggtggaagc tgctcgtcgt gcaaaagcaa tggttgctaa gatggatgaa ctgggctttg
     4921 gtaactgtac gaacactcgc gcttgcgaaa tggaatgtcc gaagaacatc tccgttagca
     4981 acatcgctcg cttgaaccgc gagttcatct ctgctaagtt acaagactaa tacattatat
     5041 atatgtatat ggaaaagccc gtcgtcaatg gcaacgggct ttctttatgt tcgttcaaac
     5101 ccacaaaaaa gccgcactcc ctataataaa agtggatgcg gcttttttgt tgctttccag
     5161 tgaaacagtc tctcgattcc ctctctgcaa agactttgtt aaccttagat ctaaaatact
     5221 atgaaaaaaa ctcactgcaa atataaagta tatttactga atacgcaaga gtttgtaatt
     5281 acattttatt gcaaatttgc tactttttgt tttaaaattg acactgtgtg cggattcaca
     5341 ctgttattat atcaacaatc gatcgattct gacacttgag agtcgctttg aaatccgtat
     5401 cctgtatgaa atttgtcggg gatggaatcc agaatgtcga ataatgcttc cactgtttcc
     5461 gcacgtagca tggcgacgcg tgtctgcttg aagtctgcaa tacctttaaa cagcggagtt
     5521 gcagccaaat ggcggcgaat gtggagaatt ccccggcgct catccaaacg ttccacgctt
     5581 tgttccacct gctttttcag tatgttcaga taccatgaaa aagattcggc aggcaatgtc
     5641 tcgcctgtat ccagataatg cctcacttct ctgaaaatcc aggggcggcc tatgctgccc
     5701 cggccaatca taacggcatc cacgccatat tgttcgaaac gttgtttgca gatttcggcg
     5761 gaagtcacat cgccattgcc gatgatggga atttgtatgc ggggattgtt ttttacttca
     5821 ccgatcagtg tccagtctgc ctctcctgta tacatctgtg cccgggtacg tccgtggatg
     5881 gaaagggctg cgataccgca atcctgtagc tgttcggcca agtctacgat gatccggttg
     5941 tcggcatccc agcccaagcg ggtttttacg gtgacaggga tgttcaccgc tttgacgact
     6001 tcacgggtga tgtccagcat cagtggaata ttgcgcagca tgccggcgcc tgctcctttg
     6061 cctgccactc gtttgacagg gcaaccgaaa ttgatatcga gaatgtccgg atgagcggct
     6121 tcgcaaattt gcgcggcttc gaccattgtc ggaacatcac ggccatatat ttgtatggcg
     6181 accggacgtt cttcatccgc cacattcagc ttttgctgtg ttttatttac actgcggatc
     6241 agggcgtctg ctgaaacgaa ttcggtataa accatatcgg caccaaaacg tttgcacatc
     6301 aaccggaaag aaatatctgt aacgtcttcc atcggagcta agaagacggg gcgttcgcct
     6361 aaatctattg tacctatttt catatttata ttatcaatga cggggacaaa ggtactgatt
     6421 tcctgctaaa aacagggata aaaggatatc tactaaaaag tgtagtaatt gatcaataga
     6481 aagtacaaat gtcatactgt caatgatata gataaaatga taagctgaaa tcatgatagt
     6541 tgcatgatag tagtatgata gttaaaaata gaaactatca tgtcttaagg tattgaataa
     6601 cagattctaa aggacaacaa tgacagtatg atggttgttt tgcaaatctt tatagaaaat
     6661 ggtatttgat cacgattttg atgctctgag aaacggatac ccatgcaatt cttctcggat
     6721 attattccta cctttgcgaa cgaaccagta aatgtataag aacttgaacg agaaagattt
     6781 tgaaataatg gcgcctgtcg gttcgtacga atcactgatg gcggctatcc aagggggagc
     6841 cgattctatc tatttcggta tcgaaggatt gaatatgcgt tcgcgctctt ccaataactt
     6901 tacgacagac gatttgcgca agatcgttgc gctttgtcgt gagcacggta ttaagagcta
     6961 tttgaccgtc aatacggtta tttatgggga agacctgcct ctgatgcgcg agattatcga
     7021 tgcggcgaag gaggcggaag tttcagcgat cattgcggcc gatgtggcag ctatgaacta
     7081 tgccaacagc atcggacagg aggtgcatct ttccacacag ctcaacattt ccaatgcgga
     7141 agcactgaaa ttctatgccc gttttgccga tgttgtcgtc ttggcgcgtg agctgaattt
     7201 gaaacaggtg catgaaatct atcggcagat cgtcgaccag cagattacgg gaccgaaagg
     7261 agaactgatc cgtatcgaaa tgtttgccca cggagctctc tgtatggccg tttccggtaa
     7321 atgttacctg agcctgcacg aaatgaacgc ttccgccaac cggggagctt gcatgcagat
     7381 ttgtcggcgt gcttattcgg taaaagataa agacagcaat atcgaactgg atatcgaaaa
     7441 ccagtatatt atgtcgccta aagaccttaa gacaattcat ttcatgaata agatgatgga
     7501 tgcaggtgta cgggtattca agatcgaagg acgtgcccgc ggtcccgaat atgtccgcct
     7561 ggtgaccgaa tgctataagg aagctgtgcg tgcttattgc aatggcacgt tcgatgaaaa
     7621 gaaagttgcc gcttgggacg aacgcctgcg cagtgtgttc aaccgaggat tctgggacgg
     7681 ctattatttg gggcaacggt tgggtgagtg gagtagcaaa tatggctccg gcgcgactaa
     7741 gaagaaagtg tatgttgcca aaggaatcaa atatttcgac aagatcggcg tggcggagtt
     7801 cgaaatggaa tccggtaacc tgaaagtggg tgatgagatc ctgattaccg gaccgacaac
     7861 gggtgcggtt atgcagacga tagaagaaat ccgtgtggac ttgaagccgg tggacgagac
     7921 cgttaaaggt gaacggttct ctctcaaggt gaacgagaag attcggccgt ctgaccgatt
     7981 gtataaaatg gaaaaggttc aacttgaaaa ggtatttgaa taatgaaaga gtatattttt
     8041 aaactgacag acaaggtccg tgactacgaa tgcgacctgc aaggagtggt caacaactcc
     8101 aattatcagc attatatgga acatactcgg catgaattct tggagtcgct tggcgagaac
     8161 ttcggaaaga tgcacgaaaa aggggttgac ggatttgtat cgcgggtaga aatccagtat
     8221 aagacctcgc tcaagagcgg cgacagctat atctcttgcc tcaatgtcta taaaaaagga
     8281 gtcaagctcg tattcgagca ggatatatat agggcttctg acaatgcatt ggcgacgaaa
     8341 ggaatcgtcg agtcggttat cgttgagaac ggaaagttga cacgcggtga atatttcgac
     8401 gaaatgctaa aaagaataga acatacatga ctgacaaacg gatttaccaa atcggcctta
     8461 ctatgataaa cggcgtggga gatatcctgg cgcgtcatct cctgcaggct ttgggagaag
     8521 cagaggctgt gtttactgaa aagcaacagt tgttaggaag gatccctggt atcggcagca
     8581 atattgctgc cgaaatcaaa cgcccggaaa tcttgcaacg ggcggaaaaa gagttggctt
     8641 ttatcgagaa aaacaatatt tcctgttatt atctgactga tacagattat ccggtgcgct
     8701 tgagagaatg tccggatgcc cctatacttt tctattttaa gggaaatact aaccttgatg
     8761 cgacccgtat catcagtatt gtgggtactc gcaacgcgac cgaatatggt cgggagctta
     8821 ccgaatccct tataaaagac ttggcaaaag tgatcccgga cttgttggtc gtgagtggat
     8881 tggcttacgg catcgatatc tgtgcccacc ggaacgcttt gtacaaccga cttccgactg
     8941 ttgctgtgct ggcgcatggc ttggatcgta tctatccttc ctgccatcgg aatacggctg
     9001 tcgaaatgct ggaatcgggc ggtctgttga ccgattttcc cagcggtaca gaaccagacc
     9061 gtccaaattt cctccggagg aaccggattg tcgccggaat ctcggattgt acgatcgtgg
     9121 ttgaatcggc agaaaaagga ggctctttgg taactgccga tattgcattc tcttatggcc
     9181 gggatgtcta tagctttcca gggcgcatcg gtgacagcca ttccaaagga tgcaacaatt
     9241 tgatccgaca aaataaagcc ggcctgatca cttctgcgga cgatctgctc tccgctcttt
     9301 gttgggatat ccaagctggg gctacttccg ttcaaacgga gttgtttttc gccgaggcgg
     9361 aaacattcac ctcggaacaa aatccggttt tagccattat gcgaacgcgg aatgagatcc
     9421 atatcaacga gcttgcctca gtgttggaga taccggtaca tcaactctct atgctattgt
     9481 tcgaactgga aataaacggg aaggtaaaag cgttgccggg aaatctctat aagctgtcct
     9541 gaccggcttt ttcgtatacg atttgtatgt gggagaagaa acggaacctc tataaacaat
     9601 taaaggctgt ctcacgacaa cccctaacca actttgttaa ccttaaatct aatactatta
     9661 tgaaaaaacc acattgcaaa gatacactcg tcaagagcgt ttgtcaagca ttttgtcgct
     9721 aatacttgtt aatcagatga gcataaatag caaaaagatt ttaatcggct ataaagagtc
     9781 ctttaaactg cgttattttg ttaaatcgag tccttgaaac aggtacggat agtccgtttc
     9841 gatcacgtcg ggacgagtgc tgatctctga ccggtaaccg gcggttttct ctgtttccgt
     9901 tttcgcgcga tcatgtgtcg gagcaacgga aatcatgcac atgactccgt tacggtgcag
     9961 agcgtcatac agtggttgct gttcaggctt catcttcggg cctacataag ccattacctg
    10021 tttccagggg atgccggctt tttcataatt atcgaattct tcccgattct tacaccagca
    10081 agaaaacatc gcatccggtt tccggtcgag ataatagcgg gcttgactgg cgttatgtac
    10141 cgtgtacatg acgttaacag gcttttctgt ttctataaaa tcagccataa cttctaaagg
    10201 tacatccttg atatccaaat tcaggattgt tttgcctttg ctccattcca ggcattcttt
    10261 taaagttgga attttgaagg ctgtcacgtt gccgtttcgg tccaccagat tgaattgttg
    10321 cagttctgca taagtgtaat ctgaaacctt tcctttcccg gtagttgtcc ggtcgatggt
    10381 ttcgtcgtgc atcaatacga ttatcccgtc ttttgtcaaa cgcggatcta tctcgaaaaa
    10441 cgattccata taggacaagg tcttttcgaa tgattcgatg cagttctccg gatagccgtc
    10501 tagcattcca ccacgatgtc cactgattac aatcgggcga tcgggagcat accggaaata
    10561 ggcttgtaga tcccggctgt tcttcacagt aatgtaatga ggattttgtt ctttgtctga
    10621 agccaaaaga ttcccggcag gcataaaacc ccctaaaagg agtaccaaaa taaaagatag
    10681 cattttcatg atattgtatt tatatagatt ctttgtcaat tatgcggctt aaaagtaaga
    10741 cttttttatc agtggcgtac tataaaagca ctataaaaac atgaaaatat gacaggcaac
    10801 aagatgtgca aagaaagagg caggtatata aaaaattaag gattgtcatc tcgacaaccc
    10861 ctaaccaact ttgttaacct taaatctaat actattatga aaaaaccaca atgcaaaaat
    10921 acactagcta agcttgtttg tcaaaccttt tacggataat atatgttaag ctctaatagc
    10981 tattttgtca aaaaatgttg gttatttata aactatacag attccatgta aaaactgcta
    11041 attcaaatac tttttatcgt cggaaaaagt gaaatcccat gcttaaaaag tgtccccttg
    11101 gagtatataa aatcattaat taatataggg gatgctttgg tgtggctgct tatagataaa
    11161 ttcctttttg gcgcatgcag cgaatagatg atagattatt aattgttaat acaaattaac
    11221 gcattatttc ttgcacattt acgatgtatt cgtagatttg cgatacgatc gtaaaaaata
    11281 atatagaaac atggaaagat taacaagaca ggaagaggat gtaatgcgct ggatctggca
    11341 gatcgagccg tgttttatca aagacatcct ggcgaagtat gaagagccta agcctcctta
    11401 tacgacactc gcttctattg tgaagaatct ggaacgtaag aaatacgtga aagcgaaacg
    11461 ttacggaaat acttacgaat acaggccgct gatcccacag gaggaatata aacggacgtt
    11521 tatgggaagt gtggtgaaca actatttcga gaactcttac aaggaaatgg tctccttttt
    11581 tgctaaagaa cagaagatat cgaccgatga gttgaaagag attatcgata tgattgaaaa
    11641 aggacgagaa taaactgtta aatacataat gccatgacac cggaatttgc ctacttcttg
    11701 aaggtaaatg tagcttttat actcctttat gccttctacc ggctgttctt ttataaggac
    11761 accttcttta aactacgccg taccatcttg ttggcatttt tcggggtgtc attgctttat
    11821 ccgctgatga atattcagga ttggatccgg gagcaggggc cgatagtgga agtcatacaa
    11881 atgtattcag ccattttgcc cgaaacgaca ataacccccg gcaatgttcc ccaaacaaat
    11941 tggcatgatt tgttacttcc cggtatttct tatctttatt ggagcggtgt aattgcctta
    12001 tcgttccgtt ttttagtgca gttgagcagc atcttgttac tggcacggcg gtcggaagtg
    12061 actttgatcc gtaacgtacg tgtacatctg ttgaataaac cggccggtcc tttttctttt
    12121 ttccggctgg tatttctgca tcccgacagc cattccgaga aagagatcga tgagattttg
    12181 gtacacgagt gtacgcatgt cagccagtgg cattcgattg acgtgattat ttgcgaattg
    12241 gtttgtatca tctgttgggt gaatccgttt gtctggctgt tgaaaagaga ggtacgtcat
    12301 aatctggaat atttggcgga tgatacggta cttgaatcgg gctatgacag tcgtagctac
    12361 caatatcacc ttttggggtt ggcacatacc aatagatcgg tgacctcttt atctaataac
    12421 tttaatatgc tgcatctgaa aaatcggatc agcatgatga ataagaaacg ttcccggagc
    12481 ataggtagga cgaaatactt gatttttata ccggttgtgg gcgccttgct gattttaagc
    12541 aatgtcgatg cattggcccg gatcacggac gaactgacgg aaagcacgtt tgccgatgtc
    12601 ttgctaccgg aggctatctt gccgttccct tttgtcggtg atgcttctcc tgctgaaaaa
    12661 cgtgaggagt atgtgctatc ggaggaaggt attgaggctg ccagacgtgc ccgtaacccg
    12721 gtgtttaccg ttgtggaggt aatgccggaa ttccctggcg gacagggtgc tctgctgaaa
    12781 ttcctggcga cgaatgtcag atacccggaa tcggccgtta aaaatggtat agagggacgg
    12841 gttagctgtt ctttcgttgt tggaaaagac ggggctatct cggaggcaga agtgattcgt
    12901 ggggtaagtc cggaactgaa tgaggaggct ttgcgtgtga taaactccat gccggtatgg
    12961 tcgccgggga aacagcgggg caaagtggtt aatgtcaaat atacggtacc ggtaactttc
    13021 cggctttccg gtggaaagaa aaaaacatcc tctcgtatcg tgcagaggca gattaaagaa
    13081 gtcgatacgt ccggtcgtgt ctttacggta gtgcaacaga tgccggaatt tccgagtgga
    13141 caggcttcgt tgttgaaata tctggcaaca cgcataaaat atccggctat tgctcaggag
    13201 aatggaatac aaggacgtgt ctcttgctct ttcgttgtcg acacggatgg aagtttgaaa
    13261 aatattgaag tgatccgtgg aatcgatcct tcgctggaca gggaggctgt ccgggtgatc
    13321 cgggaaatgc cgaaatggaa tcctggcgta caaaacaata tggctgtagc cgtaaaatat
    13381 acggttccgg ttactttccg tttgcagtaa ttgaccagaa tcggtcatta atacgatacc
    13441 attatgaaat gtaagttttc tctattactg tttctttgcg tactgtccct ttggggacag
    13501 gcgcagagtc ttaatcttca ggaattggtc aataaaaaac aatttcagga agttgtagca
    13561 cgtgcggata gtcttactcc tgccgattca gccgattatg ctacaatgtc ggcaatcggg
    13621 caggcgtatg agggactgtt gcgctataag gaggcctatc agtgtttttc tcattgcttg
    13681 aagatggata cgaacaatgt ggatgcattg aacgccgttg ccaggaatgc gatcaatttc
    13741 ggaaggatag cggaagctaa acaatgttat cgtaaagtat tgggaaccga cagcatgaac
    13801 ttctatgcca actatcagtt ggcgcgtctc tattatcagt tgggagatta tggtcgagcg
    13861 acggaacact atcatatact tgcttccatc gaaggtgaaa atccttctat cctgaccggg
    13921 ctggctgatt gccatattaa aagagggacc ggtcctaata cgatgatcgc tctttcttta
    13981 tatgcccgtg ctttggagct gaacccggaa aatgtacgtg tggcatcttc tctgataaat
    14041 acgttattgc ggatggggga cggacaggga gctttgcagg tgtgcgatac cgccttgttc
    14101 tataatccgg ataacagcca gatacggcag agtaaaggga tggctctcta tatgacgaaa
    14161 gattataagc aggccgattc agtctatacc ggtctattgg ccgatggcga ttcttctttt
    14221 ttgaatctta aatatgcggg ggcggcccgc tatatgtccg gtcatgcact tgatggggtc
    14281 gagctgctgg agaaggccta tgaaatagat tcgacggatg tggaaacagt catgttgtat
    14341 ggcgcttccc tgggaaaaac atacgaccgt aaacgggctt atgagctttt cgatctggcg
    14401 gaaacgaata tgcagccgaa aaaattccta gttaatatgt tgacgacctt ccgaggtgat
    14461 gccttggaaa gggacggccg ttggcccgaa gcggaaaagc tgtattatgc cgcatggaag
    14521 gaagacccaa cccagttgca cttcctgtat aagatcagta cacaatactg ggatgtcgat
    14581 ccgggactct ttcagcagga ggaaaaattg caaaagacga ttttcagtag atacacttac
    14641 ctgacagcct atatgaagac agacaagtcg caaaagtatc tttataatta ccgccctttc
    14701 ttggaagcgg tttgtgaaga tgcctttttc cggaatgccg atgaagtgac gatgttggct
    14761 cccgatggga agaagacgaa gttggctgtc gctgatctgc gtgccttggt cgcccaactg
    14821 ccgcagatgc cggaagatga acgtttgagg cgcgagaaga tgcaggaaca tattaaaaaa
    14881 gccagggaaa aagaaaagga attgcgtaaa agcggtgcta aactcgatac gctcgccctg
    14941 agtaaggaag aaaaagagaa agcacggaaa atgttgaaag acgccgactt ggaatagata
    15001 gaatatctga acaatataat cgatataaat
//
