LOCUS       c00724_gnlPro..        13324 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AAMGMBKN_724.
ACCESSION   c00724_gnlPro..
VERSION     c00724_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 03:20:55
            Original ID  :: gnl|Prokka|AAMGMBKN_724
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13324
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13324
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2496:8527]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2497..8527
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..13324
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13324
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(2..313)
                     /locus_tag="ctg724_1"
                     /transl_table=11
                     /translation="MKITANKFVAVTYDLNVGEGEERELMERATAETPLKFIFGTGAML
                     PAFEDALKGLEVGDKFNFSITPADAYGEYVEEHVLDLPKNIFEVDGKFDSEMIKEGNTV
                     "
     CDS             complement(411..1661)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg724_2"
                     /sec_met_domain="Aminotran_1_2 (E-value: 2.1e-41, bitscore:
                     131.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSESKQFLNIIRIFDPDQQTELIEIMKQYNFDEIIERRGTNCVKY
                     DLLKKDFGNENLVPLWVADMDFRTPDFIVNAIKKRLEHEIFGYTFDSDSYYNSIIEWVH
                     YKHNWKIQREWLSYIPGIVKGIGFVLQCFTKPGDKVIIQPPVYHPFRIVPENMHREVVY
                     NPLKTVDDIYEMDFENLESVIDEHCKVLILCNPHNPGGVVWKKDTLVKLAEVCAKHNIL
                     VISDEIHAEMAYPQYTHHPFATVSETAANCSITFMAPSKTFNIAGIVTSYSIIPNAEIR
                     EKFYSFMEAGEFNAGTIFAYTATEAAYTYGAEWLQQMRMYITENVRFVDEYCKSKLPKI
                     KVYPPQASFLVWLDCRDLKLSQPELVSLFQDKAGLLLNDGSMFGPGGEGHMRLNIGYPR
                     SVLSSALDALKKAIDKK"
     CDS             2234..2341
                     /locus_tag="ctg724_3"
                     /transl_table=11
                     /translation="MNYCSTFAASNNNKDVRKDDEQCIAYYSRGGPSSH"
     CDS             2497..4332
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg724_4"
                     /sec_met_domain="ILVD_EDD (E-value: 1.6e-216, bitscore:
                     709.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNPLRSSYSTEGRRMAGARALWRANGLKEEQFGKPIIAIVNSFT
                     QFVPGHVHLYEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIADS
                     VEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGELDNRHLDLID
                     AMIESADTSVSDERIAQVERNACPGCGCCSGMFTANSMNCLNEAIGLALPGNGTIVATH
                     VGRTQLFRDAARQIVENAYKYYRDGDESVLPRSIATRQAFLNAMSLDIAMGGSTNTVLH
                     LLAIAQEAEAGFTMDDIDMLSRKTPCLCKVAPNTHTYHVQDVNRAGGIMGIMNELLKNG
                     LVDGNVKRVDGMTLAEAVDKFAITSPNVTDEAVKKYKSAPAHRFSIRMGSQETYYKELD
                     TDRAAGCIRDIEHAYSKDGGLAVLKGNIALDGCVVKTAGVDESIWKFAGPAKVFDSQDA
                     ACEGILGGKVVSGDVVVITHEGPKGGPGMQEMLYPTSYIKSRHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEIDIPERTINVKVSDEELAERRKAEEARGTK
                     AFTPPHRQRVVSKALRAYGKMVSSADKGGVRVVED"
     CDS             4356..6056
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg724_5"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-51, bitscore:
                     163.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKQKITGSEALLKSLIAEGVDTIFGYPGGQAIPIYDSLYDYRDK
                     LKHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGFVEYEYKKVDYIRSYQPEPDINQDRIKAAAALINKAEKPFCLVGQGVLLGG
                     AEEELKAFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKVIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDAQEEYEKVIEKELYPMNGSLKMGEVVRKVSEATGNDAVLVTDVGQNQM
                     MGVRYFKYKRTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELG
                     TIMQEKLDVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAGRTVE
                     KREELDEAIAEMLNHNGAFVLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             6069..6620
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg724_6"
                     /sec_met_domain="ALS_ss_C (E-value: 7e-18, bitscore: 54.4,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENTVGLLNQITIIFTRRQLNIETLSVSPSAIQ
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVFQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNETCVVLEKSGHYDETQALFRELSETIGVLQFIRSGRVAITKS
                     RVERLSDMLAEMERKLQEKK"
     CDS             6628..7398
                     /locus_tag="ctg724_7"
                     /transl_table=11
                     /translation="VVCELPQQKRIMDKDKSKIGEFHFVTEPYLLDFRGRVTIPMIGNY
                     LIHVASSHAAERGFGFNDMSERHTAWVLSRLAIEMIEYPAMSEPITLYTWVDEVGRLFT
                     SRCFELVDGNGKTFGYARSIWAAIDVETRRPTLLDIARLSAYVTDRPCPIEKPGKIAAV
                     ENETEGVPYFIKYSDLDINGHLNSIKYMEHLLDLFDLDLFKTKDIKRFEIAYQSEGKYG
                     MKLMLYKREADNGKYDMAICNEGKAICRAAVMWH"
     CDS             7484..8527
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg724_8"
                     /sec_met_domain="IlvN (E-value: 6.4e-45, bitscore: 142.4,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 3.4e-44, bitscore: 140.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVMNFGGVDENVVTREEFPLEKAREVLKDEVIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRPGKTYDKAVADGWVPGETLFGIEEACERATIIQVLLADAAQIE
                     CWPRIKKYLTPGKALYFSHGFAITYKERTNIIPPADVDVILVAPKGSGTSLRRMFLQGR
                     GLNSSYAIFQDATGRAWDRVIALGIGVGSGYLFETTFKKEVYSDLTGERGTLMGAIQGL
                     LLAQYETLRENGHEPSEAFNETVEELTQSLMPLFAENGMDWMYANCSTTAQRGALDWMG
                     PFHDAVKPVFEKLYREVACGNEAQRSIDTNSKPDYREGLEKELAALRESEMWRAGAVVR
                     KLRPENN"
     CDS             8671..9858
                     /locus_tag="ctg724_9"
                     /transl_table=11
                     /translation="LLKYYIMKKFQILVMLLWLSVCLAGAVESKIRLVHGPYLQNLGPD
                     EVTIVWLSDKPSVGWVELAPDDDTNFYATERPKYYDARNGVKNTSTIHTVKIKGLKPGT
                     NYRYRVFVQEVLSHVGHKIIYGNYASTDVYSKKPLVFKTSDPADNSVSFAMVNDIHGKN
                     DLLTNLVSKCDLKKTDFFLFNGDMVSVFNEENHIFDGFMDTATKLFASEIPMYYTRGNH
                     ETRGAFATEFQRYFSPKEENIYYTFRQGPICFVVLDTGEDKPDSDIEYAGITVYDEYRT
                     EQAEWLRRVLDSKEYKDAPFKIIVAHIPPIGGWHGNLEVEQKFMPLLRDAKPDVMLCGH
                     LHRFIHQDATDRTPFPIIVNSNTAILKAAADPKELKIQVVDVDGKVVDQFSIKKP"
     CDS             10206..11702
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg724_10"
                     /sec_met_domain="HMGL-like (E-value: 1.1e-93, bitscore:
                     303.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRLFIFDTTLRDGEQVPGCQLNSIEKIQVAKALEELGVDVIEA
                     GFPVSSPGDFNSVVEISKAVTWPTICALTRAVEKDIDVAAEALKYAKHGRIHTGIGTSD
                     YHIRYKFNSNQEDILERAVAAAKYAKRYVEDVEFYCEDAGRTDNEYLARVVEAVIKAGA
                     TVVNIPDTTGYCLPDEYGAKIKYLMDHVDGIENAIISTHCHNDLGMATANTVQGVLNGA
                     RQVEVTMNGIGERAGNTSLEEIAMIFKSHKERGIITNINTTKIYGVSRMVSSLMNMPIQ
                     PNKAIVGRNAFAHSSGIHQDGVLKNRESYEIIDPKDVGIDDNAIVLTARSGRAALKHRL
                     QVLGVELSQEKLDKVYEEFLKLADRKKDINDDDILMLAGKDRTAMHRIKLEYLQVTSGV
                     GLQSVASICLNIAGERFEAAASGNGPVDAAIKAVKSVIHRTMTIQEFLIQAINKGSDDM
                     GKVHMQVEYEGNRYYGFAANTDIIAASVEAFIDAINKFVK"
     CDS             11713..13107
                     /locus_tag="ctg724_11"
                     /transl_table=11
                     /translation="MNTLFDKIWDSHVVTMIEEGPTQLYIDRLYCHEVTSPQALASMRR
                     RGLKPVRPERIYCMPDHNTPTHDQDKPIEDPVSKNQVDTLAKNAAEFGLTHYGMMDERN
                     GIIHVVGPERGLTLPGMTIVCGDSHTSTHGAVGAVAFGIGTSEVEMVMASQCILQAKPK
                     TMRICVEGNLGKGVTAKDVALYIMSKVTTSGATGYFIEYAGAAIRSLTMEGRLTLCNLS
                     IEMGARGGMIAPDETTFAYLKGRENAPAGEEWDKAVAYWKTLKSGDDAVFDKEILFDAA
                     DIEPMVTYGTNPGMGMGVTEHIPTVEGMNDVEKASFMKSMEYMGFEPGESLLGKKIDYV
                     FLGSCTNGRIEDFRAFASIAKGRKKADHVVAWLVPGSWLVDAQIREEGLDKIFEEAGFR
                     LRQPGCSACLAMNDDKIPAGKYAVSTSNRNFEGRQGPGARTILAGPLVAAAAAVTGEIT
                     DPRTFF"
     CDS             13135..13323
                     /locus_tag="ctg724_12"
                     /transl_table=11
                     /translation="MKQKFNIITSTCVPLPLENVDTDQIIPARFLKATDKKGFGENLFR
                     DWRYDKQGNKIESFVLND"
ORIGIN
        1 gtaccgtgtt gccttctttg atcatttccg agtcgaactt gccgtctacc tcgaaaatat
       61 tctttggaag atccagtacg tgttcctcca catattcgcc gtatgcatca gccggagtta
      121 tagaaaaatt aaatttgtcg cctacttcca gtcctttcag agcgtcttca aaagcgggga
      181 gcatagcgcc tgtaccaaag atgaatttca gaggtgtttc agctgttgct ctttccatca
      241 attcgcgttc ttcgccttcg cctacgttca gatcgtaagt aactgcaacg aacttatttg
      301 ctgtaatttt catttgtaat tgtatttatg ataaataaaa tggcaacaaa tttacgcata
      361 atttccgact tgtctgccca atctctggat aattaaatag gcaaacgact ctatttctta
      421 tctatcgctt ttttcaaagc atccagtgcg gaagacagga cggaacgcgg atagccgata
      481 ttcaaacgca tatgcccttc acctccggga ccgaacatgc ttccgtcgtt cagcaacagg
      541 ccggctttat cttggaacaa gcttaccagt tcaggctggc ttagtttcag gtcacggcaa
      601 tccaaccata caaggaaaga tgcctgaggg ggatagactt tgatcttcgg gagtttggat
      661 ttgcaatatt catctacgaa gcggacattc tcagtgatat acatccgcat ctgttgcaac
      721 cattcggctc cgtatgtata agccgcttct gttgccgtat aggcaaagat cgtcccggca
      781 ttgaattctc ctgcttccat gaaggaatag aatttttctc gtatttccgc attgggaatg
      841 atcgaatagg aggtgacgat tccggcaatg ttgaaagtct tgctcggagc catgaaagta
      901 atgctgcaat tggcggctgt ctccgaaacc gttgcaaacg gatgatgcgt atattgcgga
      961 taagccatct ctgcatgtat ttcatcggag ataacgagta tattgtgttt ggcacaaacc
     1021 tcggccaact tgaccagtgt gtcttttttc cagacgacac cgcctggatt atgagggttg
     1081 caaaggatca ggactttgca atgctcatcg atgaccgatt caagattctc gaaatccatc
     1141 tcgtaaatgt cgtctactgt tttgagcggg ttgtagacaa cctcacggtg catgttttcc
     1201 ggaacgatgc ggaaaggatg gtagaccggt ggctggataa ttactttgtc accaggtttg
     1261 gtgaagcact gcaaaacgaa accgattccc tttacgatgc cgggaatata actaagccat
     1321 tcgcgttgga ttttccagtt atgtttataa tgtacccact cgatgatact gttataatag
     1381 gaatccgaat cgaatgtgta cccgaaaatc tcatgctcca gacgcttctt gattgcgttg
     1441 acaataaagt ctggtgtccg gaaatccatg tcggctaccc aaagtggaac aaggttctcg
     1501 ttaccgaagt ctttctttag aagatcgtac ttgacacaat tggttccacg acgttcgatg
     1561 atctcgtcaa agttgtattg tttcattatc tctataagtt cagtctgttg atcggggtca
     1621 aagatacgaa ttatatttag aaactgtttc gattccgaca tttgggtagt tacacaaccg
     1681 gacttttaat tttgtctcgt cctgaataga ttgactgtgt attaaaaaat cctgttatag
     1741 gttgtctata aatgtaaata actgacactt gtaaatgagt cgggtacgaa aagtatcata
     1801 gagtggcaac tgccatactt ttatcgtcag gctataaagc catagagctt ttgacctacg
     1861 tcgaatatct ttttgcccaa ggtcgaaaag gcttttgcca ttaggcaaaa aggctttcgg
     1921 ccttgggcaa aaacgtaaga agttataatt aaatctgtac gagacagggt gaaagcagat
     1981 ctttaaggtg aagccagtcc gaatgtctgc cttcacctta aagatctgct tttattttaa
     2041 tatatagcaa gacgatggtg aagcctactc gcatattctt tcatatgaaa agttaggcgg
     2101 aaacaatcca gacaggtatt tcggatttga taatggaaga ttggaaggat gtgttaaact
     2161 gcaagcctat cttgtttctt tgcttgagaa atgtaagata aattgatatt tttcttttaa
     2221 tttctttgga ggtatgaatt attgttctac atttgcagcg tcaaacaata ataaagacgt
     2281 aagaaaagat gatgaacaat gtattgcata ttattctcgt ggtggtcctt ctagtcatta
     2341 gcaggtaagg agaaaggtgt gcaagaaatt gtgaagtcgt ataaagatat ttcttaagcc
     2401 tttctccata cagagaaggg cttttttaat ataataatat ttaggataag aaaatagggg
     2461 cggttcgtga gccgttcgaa aacaacaaat aatatgatga agaatccgtt aagaagttca
     2521 tacagcacag agggcagacg catggccggg gctcgcgctt tgtggcgtgc caacggtctg
     2581 aaagaagagc agttcggtaa accgattata gccattgtga attcatttac ccagtttgta
     2641 cccggccatg tccatctgta tgagatcggg cagcaggtaa aagcggagat tgaaaagttg
     2701 ggttgctttg ctgccgaatt caatacgatt gccattgacg atggtatcgc tatgggacac
     2761 gacggaatgc tctattcgct tccttcgcgt gatattattg cggacagcgt cgagtatatg
     2821 gtgaatgccc acaaagccga tgcaatggtt tgcattagca attgcgacaa gatcactccg
     2881 gggatgctaa tggcatccat gcggctcaat attccgacta tctttgtctc cggcggtccg
     2941 atggaagccg gtgagctgga taaccgccat ctggatttga tcgatgccat gatcgaatcg
     3001 gccgacactt cggtcagcga tgaacggatc gcgcaggtgg aacggaatgc ctgtccggga
     3061 tgcggttgtt gttccggtat gtttacggcc aactcgatga actgcctgaa cgaagcgatc
     3121 ggcctggctc ttccgggcaa cggtacgatt gtcgctacgc atgtgggccg tacacagctg
     3181 ttccgcgatg ctgcccggca gattgtagaa aatgcctata aatactatcg tgacggagat
     3241 gaatcggttc ttccccgcag tatcgctacc cgtcaggctt tcctgaatgc catgtcattg
     3301 gatattgcaa tgggtggttc caccaatacg gttctccact tgctcgccat cgcgcaggaa
     3361 gctgaggcgg gcttcacgat ggacgatatc gatatgctct cccgcaagac tccttgcctc
     3421 tgcaaggttg ctcccaacac gcacacctac cacgtccagg atgtgaaccg tgccggtggt
     3481 atcatgggaa tcatgaacga gctgctgaaa aacggcttgg tagacgggaa tgtgaagcgt
     3541 gtggacggaa tgacgcttgc cgaagccgtg gataaatttg ctatcacctc gccgaatgtg
     3601 acggacgagg ctgtcaagaa atacaagagc gctcccgccc atcgtttcag cattcggatg
     3661 ggatcgcagg aaacctatta taaggaactg gataccgatc gtgccgccgg atgtatccgt
     3721 gatatcgagc atgcttattc caaagatggc ggcctggctg tcctgaaagg aaatatcgcg
     3781 ctggacggtt gtgtggtcaa gacggccggt gtggatgaaa gcatctggaa gtttgccggt
     3841 ccggcgaaag tgttcgattc gcaggatgcg gcttgcgaag gcatcctcgg tggaaaagtc
     3901 gtctcgggcg atgtggtggt gatcacacac gaaggaccga agggtggtcc gggtatgcag
     3961 gaaatgcttt atcctacttc ttatataaaa agccgccatt taggcaagga gtgcgcgctg
     4021 atcacagacg gtcgtttcag tggcggtact tccggtcttt ctatcggtca tatttctccc
     4081 gaagctgcgg caggaggagc gattggactg gtgaaagacg gcgatataat cgagattgat
     4141 atccctgaac gtacgattaa tgtgaaggta agcgatgaag agttggcaga acgccgtaaa
     4201 gcggaagaag cccgcggcac aaaagccttt acgccgcctc atcgccagcg tgtcgtctca
     4261 aaagccttga gagcttacgg taagatggtc agttcggccg ataagggtgg agtgagagta
     4321 gtagaagatt aaacacaaga ctaaaataaa gagatatgga gaaacagaag ataaccggtt
     4381 cggaagcttt gctgaagtca ctgatagctg aaggagtaga tacgattttc ggttatcccg
     4441 gcgggcaagc gattcctatt tacgatagtt tgtacgatta cagggataaa ttgaagcatg
     4501 tattggtgcg tcatgaacaa ggggcgacgc atgctgcaca agggtatgcc cgtgtatccg
     4561 gtaaagtagg ggtgacgttg gttacttcag gacccggcgc aacaaatacc atcaccggca
     4621 ttgccgatgc actgatggac agcacgccta tggtggtcat agccggacag gtcccttctc
     4681 cattgcttgg aacagatgct ttccaggaag tcgatgtgat cggcattacg caaccgatca
     4741 ccaaatgggc gtaccagatt cgcaagccgg aagagatagc gtgggctgtt tcacgtgctt
     4801 tttatatcgc ttctaccgga cggccggggc ctgttgtact cgatttggca aaggatgctc
     4861 aggtcggatt tgtagagtat gaatataaga aagtagacta tatccgcagc tatcagccgg
     4921 aaccggatat caaccaggat cggattaaag cggctgccgc gttgatcaat aaagcggaga
     4981 aaccgttctg cctggtcgga cagggtgttc tgttgggagg tgctgaagag gagctgaaag
     5041 cattcctgtt gaagaatgac attcctgccg gttcgactgt tctcggtcta tcggcgttgc
     5101 cttccgattt tcctttgaat aagggtatgt tgggtatgca cggcaatgtc ggtccgaaca
     5161 ggaagaccaa tgaatgtgac gtgttgatcg ccatcggtat gcgtttcgac gatcgtgtta
     5221 caggtgattt gaagacatac gccaagcagg cgaaagtgat ccatttggat atcgacaact
     5281 cggagatcgg gaagaatgta ccggtcgatg tgaaggttct cggaaatgcc aaacatacca
     5341 ttccgatgat aactgcgttg ttggaagaac ggaaacgtcc ggagtggaat gctgagtttg
     5401 agccggatgc acaggaagag tatgaaaagg tgatcgagaa ggagttgtat ccgatgaacg
     5461 gatctttgaa aatgggtgaa gtcgttcgaa aagtgtccga ggcgaccgga aacgatgctg
     5521 ttttagttac ggatgtcgga cagaaccaga tgatgggtgt ccgctatttc aaatataaac
     5581 gcactcgtag cgtggttact tcaggtggtc tggggacgat gggctttggc cttcccgctg
     5641 ctatgggagc caagttcggt gcacctgacc gtacggtctg cttctttacc ggtgacggtg
     5701 ggatgcagat gacgattcag gagttgggaa ccattatgca ggaaaaactg gatgtgaaaa
     5761 tcattatcct caataataat ttcttaggaa tggtacgtca gtggcaggag ttgttcttcc
     5821 acgaacgtta ttcgaatacg atcatggaga acccggattt cgtggcgatc gcgaaagcgt
     5881 acggtatcgc tggccgtacc gttgaaaaac gggaggaact ggatgaggct attgccgaga
     5941 tgttgaacca taacggagcg tttgtgttgg tcgccaatgt ggaaacgtgt ggtatggtat
     6001 atccgatggt gcctgccgga ggaagcgtaa cgaacatgat attaggagat aagtaaggag
     6061 gtgaagctat gacaacaaaa aaattatata ccgttattat cttttcagag aatacagtag
     6121 gtcttctgaa ccagattacg attatcttta cgcgtcggca gttgaacatc gagacgcttt
     6181 ccgtttcacc ttccgccata cagggtatac ataaatttac aatcacgaca tttgccgatg
     6241 aagatatgat cgacaaggtt gtgaagcaga tcgacaaacg ggtggatatc ttgaaggctt
     6301 actataatac ggatgaagat ctggttttcc aggagatcgc cctttataag ctgagcaccg
     6361 agctgtttat caagatgggg acggtcgagg atctgattcg caaatataac gcccgtattc
     6421 tggaaatgaa cgaaacgtgt gtcgttctcg aaaagagtgg tcattacgat gagacgcaag
     6481 cccttttcag ggagttgagc gaaacgatcg gtgtcttgca gttcatccgt tccggtcgcg
     6541 ttgcgatcac aaaaagccgt gtcgagcgtt tgagcgatat gttggccgaa atggaacgta
     6601 agttgcagga aaaaaaataa cgtacgggtg gtttgcgaac tgccccaaca gaaaagaatc
     6661 atggataaag ataaaagcaa aataggggaa tttcatttcg tcacggaacc gtacctgttg
     6721 gattttcgtg gacgtgtaac gataccgatg atcggaaact atctgataca tgtcgcatcc
     6781 agccatgctg ctgaacgcgg attcggtttc aacgatatgt cagaacggca tacggcttgg
     6841 gttctttccc gtctggcgat cgaaatgatc gaatatccag ccatgtccga acctataact
     6901 ctttatacct gggtggatga agtcggccgc ctctttacca gccgttgttt tgagctggtg
     6961 gatggcaacg gtaagacatt cggttacgcc cgttctattt gggcggctat cgatgtggaa
     7021 acacgccggc cgaccttgtt ggatatcgcc aggttgagcg cttatgtcac ggatcgcccc
     7081 tgcccgatag aaaagccggg aaagattgcg gctgtggaga atgagacgga aggggttcct
     7141 tatttcatta agtacagcga ccttgatatc aacggccacc tgaacagtat caagtatatg
     7201 gaacatcttc tagacctgtt tgatcttgac ctgttcaaga caaaagatat caaacgtttc
     7261 gaaatcgcct accagtctga aggcaaatat gggatgaaac tcatgttgta caagagggag
     7321 gctgataacg gaaaatatga tatggcgatc tgtaatgaag gcaaagcgat ttgccgtgct
     7381 gctgttatgt ggcattgaac aaacatggta cgggcggatg gtttgcgaac tgtcctgaca
     7441 aaagaattat tttattaaca cattacattt aatagtagaa aaaatggcag taatgaattt
     7501 tggcggtgtt gacgaaaacg tagtaacccg cgaagaattt ccgttggaaa aggcaagaga
     7561 agtattgaaa gatgaagtga ttgcagttat cggttacggt gttcaaggtc ctggacagag
     7621 cttgaacttg cgtgataatg gtttcaacgt tatcgtagga cagcgtcctg gtaaaaccta
     7681 tgacaaagct gttgccgacg gctgggtacc gggtgaaaca ctgttcggta ttgaagaagc
     7741 ttgcgaaaga gcaactatca tacaggtgtt gcttgccgac gccgctcaga tcgaatgctg
     7801 gccgcgtatc aaaaaatatc tgactccggg aaaagcgctg tatttctctc atggttttgc
     7861 tatcacttac aaggaacgta ccaatattat ccctcctgct gatgttgacg tgattctagt
     7921 cgcaccgaaa ggttctggta cttctttgcg tcgtatgttc ctgcagggac gtggcttgaa
     7981 ttcaagctat gcaattttcc aggatgcaac cggtagagca tgggatcgtg tgatcgcttt
     8041 gggtatcggc gttggttcag gctatctgtt cgaaacgaca ttcaagaagg aagtttattc
     8101 cgatctgact ggtgaacgtg gaactttgat gggggctatc caaggtttat tgttggctca
     8161 atacgaaaca ttgcgtgaaa acggccacga accttccgaa gcattcaacg aaacagtcga
     8221 agaactgact cagtctttga tgccgctgtt tgctgaaaac ggaatggact ggatgtatgc
     8281 aaactgttcg actactgcac agcgtggcgc tttagactgg atggggccgt tccacgatgc
     8341 cgttaagcct gtatttgaaa aattataccg ggaggtcgcc tgcggtaacg aagcgcagcg
     8401 ttctatcgat acgaacagta agccggatta tcgtgaaggt ttggaaaaag aactggcagc
     8461 attgcgcgaa agcgaaatgt ggcgtgcagg tgcagtcgtt cgtaaattgc gcccggaaaa
     8521 caattgatag acatcgcatt ttttatttga gtgcataaag aaagtggcaa ttcggtatga
     8581 attgtcactt tttttaatga aaatgtatca ttttgataag aaatttttga atagtaatcg
     8641 atatcttcgt agctataaat tcgaatttaa ttgcttaaat attatatcat gaagaaattc
     8701 caaattttag taatgttatt gtggctgtct gtttgtctag caggagcagt agagtcgaag
     8761 attcggttgg tgcatggtcc ttatttgcag aatctagggc ctgatgaggt gacgatcgtg
     8821 tggttgtcgg ataaaccttc tgtcggttgg gtggagctgg cgccggatga cgataccaac
     8881 ttttatgcta ccgaacgtcc caaatattat gatgcccgta acggagtaaa aaatacatct
     8941 acgatccata ccgtgaagat caaagggctt aaaccgggta cgaactaccg ttatcgtgtc
     9001 ttcgtacagg aagtactgag ccatgtcgga cataagatca tctatgggaa ctatgcctcg
     9061 actgatgttt actccaaaaa gccgttggtg ttcaagacga gcgatcctgc ggataattcc
     9121 gtctcatttg cgatggtgaa cgatatacat ggcaaaaatg acctgttgac gaacctagtt
     9181 tccaagtgtg atttgaaaaa gacggacttt tttcttttta acggtgatat ggtgtcagtc
     9241 ttcaatgagg aaaatcatat cttcgacggt tttatggata cggcgaccaa gctgtttgcc
     9301 tctgagattc cgatgtatta tacaagaggc aaccacgaaa cacgtggcgc ttttgcaacc
     9361 gagttccaac gttatttctc tccaaaagaa gagaatatct actatacatt ccggcaaggt
     9421 ccgatctgtt ttgtcgtttt ggatacggga gaggacaagc cggattccga tattgaatat
     9481 gccggtataa cagtctacga cgaataccgg acagaacagg ccgaatggtt gcgccgagta
     9541 ttggatagca aagaatataa ggacgcgccg tttaaaatta ttgtagccca tatcccaccg
     9601 atcggcggat ggcatggaaa cttggaagtg gagcagaagt tcatgccttt gctacgcgat
     9661 gccaagccgg acgttatgtt gtgtggtcac ctccaccgtt tcatccatca ggatgcaacg
     9721 gatcgtacac cgttcccgat tatcgtcaat tccaatacgg ctattttgaa agcggctgcc
     9781 gatccgaaag aactaaaaat acaggtcgta gatgtggacg ggaaagtggt ggatcaattc
     9841 tccataaaga agccttgaaa aatgataagt agattgttgg ttatgaattg aagaatttag
     9901 atgtatttgt cttttatttt ataagaaaat agtgataaaa actttaaatt atatttggat
     9961 gtttggaaaa agaccgtatc tttgcagcgt tcaaacaaaa acggttgaaa agacaatatg
    10021 aaacaggtaa tgctaaatag tctcattatt tctctaaaca ttattctact ctgggaacgg
    10081 aataggaagt gagactgtgt atgctttaca gggcattaag atatgaaaaa gcctttctcg
    10141 cttccttgtg agagaggctt ttttcattca gaaaagatat taacaaattt aagacgataa
    10201 gaactatgtc agacagatta tttattttcg acacgacatt gcgtgacggt gaacaagtgc
    10261 cgggttgcca gttaaatagt attgaaaaga ttcaggtagc caaagctctg gaagaactgg
    10321 gagtagacgt gatagaagcc ggttttcccg tatcgagtcc gggagatttc aatagcgttg
    10381 ttgaaatatc gaaagccgta acgtggccta caatctgtgc gcttacccgt gcggtagaaa
    10441 aagatattga tgtggctgcc gaagcactga aatatgcaaa gcacggacgt attcatacag
    10501 gtattggaac gtccgattat catatcaggt ataagttcaa ttcgaatcag gaagatattt
    10561 tggaacgggc tgtcgctgct gccaaatatg ccaagagata tgtggaagac gtcgaatttt
    10621 attgcgaaga tgccggacgt actgacaacg aatatctggc acgtgtggta gaagcggtca
    10681 tcaaagctgg cgcgacagtt gtcaatatcc ctgatacgac cggttattgc ctgccggacg
    10741 aatatggggc gaaaatcaaa tatctgatgg atcatgtaga cggtatcgag aatgctatca
    10801 tttctaccca ctgtcataat gatttgggga tggctaccgc caatactgtg cagggtgtct
    10861 tgaatggtgc acgtcaggtg gaagtcacca tgaacggtat aggtgaacgt gccggtaata
    10921 catccttgga agaaatcgcg atgattttca agagtcacaa agaacgtggc attattacca
    10981 atatcaatac gacaaagatt tacggagtca gccgtatggt gtctagcctg atgaacatgc
    11041 ctatccagcc gaataaggcg atcgtcggac gtaacgcgtt cgctcattct tccggcatcc
    11101 atcaggatgg cgttttgaag aatcgtgaaa gttatgaaat catcgatccg aaagatgtag
    11161 gaatcgacga taatgcaatc gtgctgactg cccgtagcgg acgtgcggca ttgaaacacc
    11221 gtttacaggt attgggcgtc gaattgtctc aggaaaaact agataaggtt tatgaagaat
    11281 tcttgaaact ggctgaccgt aagaaagata tcaacgacga cgatatcttg atgcttgctg
    11341 gcaaagaccg cacggccatg catcgtatca agttggaata tttacaggtg acctccggtg
    11401 tcggtttgca gtctgtggcc agcatttgcc tgaatatagc tggtgagagg tttgaggccg
    11461 ccgcttctgg caacggtcct gttgatgctg ctatcaaggc ggtgaaatct gttatccacc
    11521 gtacgatgac gattcaggag tttttgattc aagcgattaa taaaggcagt gacgatatgg
    11581 ggaaggtaca tatgcaggtt gagtacgaag gaaaccgtta ttatggtttt gctgccaata
    11641 ccgatattat agccgcttct gtagaggcat ttatcgatgc aattaataaa tttgtgaagt
    11701 gaattgataa ttatgaatac attatttgac aagatttggg attcccacgt agtgacgatg
    11761 atcgaagagg ggcccacaca actttacatt gacaggttgt actgtcatga agtaactagt
    11821 ccacaggctt tggccagtat gcgtcgacgg ggtttgaagc cggttcgtcc ggaacgtatc
    11881 tattgtatgc cggatcataa cacgccgaca cacgatcagg ataaaccgat cgaagatcct
    11941 gtttcgaaga atcaagtcga tacgctggca aagaatgctg ccgaatttgg tttgactcat
    12001 tatggaatga tggatgagag gaatggtatt attcatgtgg taggcccgga acgtggactg
    12061 accttgccgg ggatgacgat cgtttgcggt gattcgcata cttctactca tggagcagtc
    12121 ggtgcggtcg ctttcggtat cggaaccagt gaagtggaaa tggttatggc ttcccagtgc
    12181 attttgcagg caaagccgaa aaccatgcgt atctgtgtgg aaggtaatct agggaaaggg
    12241 gtgacagcaa aggatgtcgc cctttatatc atgtcgaaag tgacgaccag cggtgcaacc
    12301 ggatatttca tcgagtatgc tggtgcggcg atccgtagct tgacgatgga ggggcgtttg
    12361 actttgtgca acctgtctat tgaaatggga gcgcgtggtg gtatgatcgc tcctgacgaa
    12421 acgacattcg cttatcttaa gggacgtgaa aatgctcctg ccggcgaaga atgggataag
    12481 gcggttgctt attggaagac tttgaaaagt ggcgatgatg ctgtgtttga caaagagatt
    12541 ctgtttgatg ctgccgatat cgaaccgatg gtgacgtatg gtaccaatcc gggtatggga
    12601 atgggagtta ccgaacatat cccgactgtc gagggtatga acgatgtgga gaaagcttct
    12661 tttatgaaat cgatggagta tatggggttc gaaccgggtg aatccttgtt gggcaagaag
    12721 atcgactatg tgttcttagg ctcttgtacc aatggccgta tcgaggactt tcgtgctttt
    12781 gcttccattg ctaagggacg gaagaaagcc gaccatgtgg tcgcctggct ggttcctggc
    12841 tcctggctgg tagatgcgca gatccgtgaa gaagggttag acaagatatt cgaagaagcc
    12901 ggtttccggt tacgtcaacc gggatgctcg gcttgtctgg caatgaacga cgataagatc
    12961 ccggcaggaa aatatgcagt ttcgacaagc aaccgtaact ttgaaggacg tcaggggccg
    13021 ggggcccgta cgattctggc tggaccgcta gtagctgctg cggcagccgt gactggggaa
    13081 attaccgatc cgagaacgtt tttctgaaat cataaatcat aaattttaac attcatgaaa
    13141 cagaaattca atatcattac atcaacctgc gtcccccttc ctttagagaa tgtggatacg
    13201 gaccagatca ttcctgctcg tttcctgaaa gcaaccgaca aaaaagggtt tggtgaaaat
    13261 ttgttccgcg actggcggta cgacaagcag ggaaacaaaa tagaatcgtt tgtcttgaat
    13321 gatc
//
