LOCUS       gnlProkkaKIOFINJO_35    6793 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KIOFINJO_35.
ACCESSION   gnlProkkaKIOFINJO_35
VERSION     gnlProkkaKIOFINJO_35
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 08:35:09
            Original ID  :: gnl|Prokka|KIOFINJO_35
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6793
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6793
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[3553:6445]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3554..6445
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..6793
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6793
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(681..1583)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 189.9; E-value: 1.2e-57)"
                     /gene_kind="transport"
                     /locus_tag="ctg35_1"
                     /transl_table=11
                     /translation="MVITNIILAFFSSFSGPAYKAFTKEVVEADNISKLNSLLESFITV
                     VKVVVPLVSVSLYGLLGLYGILRLDGITFIASGLLILFIRPILEESTGKQVFSLSKIFS
                     DLFEGGRYLASQKEILYLVILSAIVNFFLAAYNLLLPYSNQMFPRVTVGLYGVFLGAEA
                     VGGLIGASLSSILNKVLKIKTMILYLGVSGVFLSLTPMVYCVFPSAYMLALYPALFNLF
                     LTMFNLQFFSYIQKNVDNVFLGRVFGIIFTVAILFMPIGTMTFTFLLSPKNIFNFVIVG
                     LSIGGISLLFYRIFSKRLR"
     CDS             complement(1655..1888)
                     /locus_tag="ctg35_2"
                     /transl_table=11
                     /translation="MNKKEQQNTYLLVGSRIISRVGDIMFDFANNTFLSSVNVKSLMLV
                     GIYQTLENIISVIFNLFGGVLSDNFQRKRIII"
     CDS             complement(1914..2375)
                     /locus_tag="ctg35_3"
                     /transl_table=11
                     /translation="MRTIQAVRDGCDILLEKDFKNIDLIFCATGSKSLDILDFRSIKDG
                     TFLVSATSSDDEFNYSYLLDEYEEIVETSLITRYESEDNYFYLLNQGTPTNFVVNSALG
                     NYILLVQAAILYTAKKFIEDREMAIAKQVNTLSDEDNYNIAKQWLEEFC"
     CDS             complement(2401..3522)
                     /locus_tag="ctg35_4"
                     /transl_table=11
                     /translation="MNNIQEKDKLNNVLVQLNEKDDQEMINRKNFIGHFTASAFVISKD
                     NRRLLMVHHNILKRYLQPGGHIDKNDRNPLDAAKRELFEETGIDSEILTYQCAEPLNSL
                     IPFNVSVHKIPENKLKNERSHYHYDLQYLFYIENEVDVKIDSNESSSYEWIQLDNVKDM
                     DGYKEIIKKIEKLEAASQERFLSNMLKGASFEDISCITVQHIIPSTIPIIMTLQKIFGH
                     RLLVCAKPNSVDKMVWHKLENMGVRLTLASRDEYFNVDYLGIKSKTILLDIGGYFASIA
                     QIPNLPIECIIEDTENGIQKYENVIDQIEYPLFSVARNPLKKNEILSWCGYCFWDRLYI
                     TSKKFINAIYASGLYWIWENRLRHLYQIKRTWY"
     CDS             complement(3554..6445)
                     /NRPS_PKS="Domain: AMP-binding (6-388). E-value: 7.5e-65.
                     Score: 210.9. Matches aSDomain:
                     nrpspksdomains_ctg35_5_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     172.5; E-value: 2e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg35_5"
                     /sec_met_domain="AMP-binding (E-value: 1.5e-64, bitscore:
                     206.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.2e-07, bitscore:
                     20.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILKTFSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLL
                     NSDEETVPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDR
                     DVKLENHSVTLLLLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNID
                     WLVKEFYKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGET
                     IEKKKITHLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRV
                     FNLYGPSETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVT
                     EGYRLQPELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQVNGIRIELDEVK
                     SIVDKLKSVKSSRVVFYKKKLVVFYEADLNIKEDIIRSLPSYLNPTVVKVESYYLNQNR
                     KLDVPKMLEIYYYKKQSQQGDDVRKNILDVLSKFERVDITDLDSLELVRFYLEIEDIFD
                     IEIKENDFYRLKSVDSIVDYIRNKSFFQERSTEPNDSFTKEHDLVNLEYNLTKMNYRYL
                     KNIITPSPTQKRLYKNNQNRVIGFNLALEEVTYLELNKLHHIIKYLSYKIDIFRLVVEK
                     EQTRFSIGIVNEGDYSPNIIVLNNLPTELELQGILDNIEVIPIPIIVVGTRDKKVRFYF
                     PYHSIDASSLNKLGDTVYQLYEKKIVIDEVPSSSLVAFSQFKREVLQNDVSGDVLARLP
                     KIKPAIEFEKLNDEVQCFQVSLPEDIKGDDVYLFTIYAISQCILSDYNLSAISGGLSLD
                     FRDYEQFDAYDLIGDIHKKIPFQVNRTETFEEFKNSHFKILEIYRTGIDYYEIAMLGND
                     MSAKEVQERLNNLSLSINFIGEAFRLKDTINNIIDVDFDKNFINVFVHERFAYAVIKSE
                     LLSNSVYDLMHKDSKFELKVIDKKRLENEETNR"
     CDS_motif       complement(4625..4672)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_5_0004"
                     /evalue="1.30E+01"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg35_5"
                     /protein_end="607"
                     /protein_start="591"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="NNQNRVIGFNLALEEV"
     CDS_motif       complement(5252..5308)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_5_0003"
                     /evalue="2.60E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg35_5"
                     /protein_end="398"
                     /protein_start="379"
                     /score="20.0"
                     /tool="antismash"
                     /translation="SRIDSQVQVNGIRIELDEV"
     aSDomain        complement(5282..6427)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg35_5_AMP-binding.1"
                     /evalue="7.50E-65"
                     /label="ctg35_5_AMP-binding.1"
                     /locus_tag="ctg35_5"
                     /protein_end="388"
                     /protein_start="6"
                     /score="210.9"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="FSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLLNSDEET
                     VPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDRDVKLEN
                     HSVTLLLLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNIDWLVKEF
                     YKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGETIEKKKI
                     THLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRVFNLYGP
                     SETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVTEGYRLQ
                     PELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQV"
     CDS_motif       complement(5384..5455)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_5_0002"
                     /evalue="2.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg35_5"
                     /protein_end="354"
                     /protein_start="330"
                     /score="19.7"
                     /tool="antismash"
                     /translation="ELLIGGNGVTEGYRLQPELNKAKF"
     CDS_motif       complement(5972..6028)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg35_5_0001"
                     /evalue="1.00E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg35_5"
                     /protein_end="158"
                     /protein_start="139"
                     /score="15.1"
                     /tool="antismash"
                     /translation="AHIICTSGTTGVPKKVFLT"
     CDS             complement(6635..6793)
                     /locus_tag="ctg35_6"
                     /transl_table=11
                     /translation="MFADNQKDLQKFVNKRLEELQKDGTLAKLAEKFFGNKDYIPTKDA
                     LKVPSKK"
ORIGIN
        1 tttattgtaa cagaattcac taagcttaac taatacttaa acataatcaa agtgataaga
       61 aaatactatc acctaaaaat atcaattgtt tgacaaagag ccgaattgct tcgtctttct
      121 gaacgcagac gggttgtctt aaacgacatg gtagctctag ctcagccttt accagagtat
      181 gacatcttac ggtcaattcc tggcatcgca gaaaccacag cgacatctat cattggcgaa
      241 ttgggagata ttcgtcgcag tataccaatc aaatcaacgc ttttattggc attgacctga
      301 gacactatga atctgggaac tttctcgcta aggaacacat cactaaacga gggaatccct
      361 atgccagtaa aatcttgttc aagtacattc acaacatcgc ttcagctagt cataccaatc
      421 cctgcaatat cgctgacttt tatgagaaac gaacaagaca tttagagcta tttctaaact
      481 aatcggcgac ccatctactg tctctaaaaa agtatgtaaa caccttacca tcaaggaatc
      541 aatcaacact caaaatgtga ggcccgccca cttctaaaac gattacctta tgtgtgtaat
      601 ggttgcccta acaagtatat aaattgtgac tttactaagc aattttacta cgccatcgga
      661 gctaaaatta ctctgaaaat ttacctcaat cttttgctaa aaatcctata aaagagaagc
      721 gaaatacctc ctatagataa accaacgata acaaaattaa agatattttt agggcttaaa
      781 agaaaagtaa atgtcattgt cccaatgggc ataaataaaa ttgcaacagt aaaaataatc
      841 ccaaaaactc taccaagaaa gacattatcc acattctttt ggatatatga aaaaaactgt
      901 aagttgaaca tagtcaaaaa caagttgaat aaagcaggat ataacgcaag catataagca
      961 cttggaaaaa cacagtatac cataggtgtc aaagatagaa aaacacctga tactccaaga
     1021 tataaaatca ttgtttttat tttcaaaact ttattgagaa tactgcttaa agacgctcca
     1081 ataagaccac ctactgcttc tgctcctagg aaaacaccgt ataagccaac ggtaactctt
     1141 gggaacatct gattgctata tggtaacaac agattataag ctgctaaaaa gaaattaaca
     1201 atcgcagata aaataaccaa gtacaaaatt tccttttgac tagctagata ccttcctcct
     1261 tcaaaaagat ctgaaaagat tttcgataat gaaaacacct gtttcccagt actttcttca
     1321 agtatgggac gaataaagag aataagcaac ccagatgcaa taaatgttat cccatctaga
     1381 cgtaaaatac catataatcc tagtaaaccg tatagagata ccgataccag gggaacaacg
     1441 actttaacta ccgttataaa cgattctagt aatgagttta gttttgaaat attatctgct
     1501 tccaccactt ctttagtaaa agccttataa gcagggcctg aaaatgatga gaaaaaagct
     1561 aatataatgt ttgtgataac cacagcataa atcaaccact gctgattaga aataaaagat
     1621 aaggcaagac acaatactcc gcttaaaata tctgttaaat gataatccgt tttctttgaa
     1681 agttatcaga cagaacacca ccaaaaagat taaaaatcac actgatgatg ttttctaatg
     1741 tctgataaat accaactaac ataagtgact taacatttac actcgataaa aaagtgttat
     1801 tcgcaaagtc aaacataata tctccaacac gagaaataat acggctccct acaagtaaat
     1861 atgtattttg ttgttctttt ttattcaaaa taaactcctc agatatttgt tcattagcag
     1921 aactcttcta accattgctt cgcaatatta tagttatcct catccgaaag agtgtttact
     1981 tgcttagcta tagccatttc tctatcttca ataaacttct tagctgtata tagaatggct
     2041 gcctggacta ataaaatata atttcccaaa gcggagttta ctacaaaatt agttggtgtt
     2101 ccttgattta acagatagaa atagttgtct tcactttcat atctagtgat taatgaagtt
     2161 tcgactattt cttcatattc atccaataaa tagctataat taaattcatc atcactagat
     2221 gttgcagaga ctaggaaggt tccatctttg atagagcgaa aatctaaaat atctagactt
     2281 tttgaaccgg tcgcacaaaa aatcaaatca atattcttga aatctttttc tagcaaaatg
     2341 tcgcaaccat cacgtaccgc ttgaatagtt ctcatgctat ctttttccag caccttcggt
     2401 ctaataccaa gttctcttaa tttggtacag atgccgtaac cgattttccc atatccaata
     2461 caaaccactt gcatatattg cattaataaa tttttttgat gtaatatata atctgtccca
     2521 aaaacaatat ccgcaccaac taagtatctc attcttcttc aggggatttc tagcgacaga
     2581 aaataacgga tattctattt gatcaataac attctcatat ttttgaatcc cattttctgt
     2641 atcttcaatg atacactcga taggtaagtt tggaatctga gcaattgagg caaaataccc
     2701 accaatgtct aataaaattg ttttactctt tatccccaga taatctacat taaaatattc
     2761 atcccttgaa gctaatgtta atcttacccc catattttct agcttgtgcc ataccatctt
     2821 atcaacagag tttggtttag cacacactaa caaacgatgc ccaaatattt tttgcaatgt
     2881 catgataatc ggtattgtac ttggaataat atgttgtaca gtaatacatg atatgtcttc
     2941 aaacgatgca cctttcagca tattagataa aaaacgttct tgagaagctg cttcaagttt
     3001 ttcaatcttc ttaatgattt ccttatagcc gtccatgtcc tttacattat ctagctgaat
     3061 ccactcatag gaactcgatt cgttgctgtc aattttcaca tcaacctcat tttcaatata
     3121 aaataaatat tgcaagtcat aatggtagtg ggaacgctca ttcttcaatt tattttctgg
     3181 tatcttatgc acagaaacat taaaaggtat caagctattc aatggttctg cacattgata
     3241 cgtcaatatt tcagaatcta tcccagtctc ctcaaacagc tcacgtttcg ctgcatctag
     3301 cgggtttcta tcatttttat caatatgccc cccaggctgt aggtatcttt ttaaaatatt
     3361 atggtgaacc atcaataaac gcctgttatc ttttgaaata acaaatgctg atgctgtaaa
     3421 atgcccaatg aaattctttc tatttatcat ctcttgatca tctttttcat taagctgtac
     3481 caaaacgtta ttcaatttat ccttttcctg aatattattc attggtaccc ctctactata
     3541 tctttataaa tactcatcgg tttgtctcct cattttccag tcgtttttta tcaattactt
     3601 ttagctcgaa tttgctatct ttatgcatta agtcataaac actattactc aataactcag
     3661 attttataac tgcgtatgca aatcgctcat gtacaaatac attaataaaa tttttatcaa
     3721 aatcaacatc aattatatta ttaatagtat cttttaacct aaatgcttcg ccaatgaaat
     3781 ttattgatag agacagatta tttaatcgtt cttgcacttc tttagcactc atatcatttc
     3841 ctaacattgc aatttcatag taatcaatac ctgtacgata gatctccaaa attttgaaat
     3901 gagagttttt aaactcctca aaagtttcag ttcgatttac ttggaatgga attttcttgt
     3961 gaatgtctcc tattaagtca tacgcatcaa actgttcata atctctaaaa tccaaagata
     4021 gacccccaga tatagcagac agattatagt cgcttaaaat acactgtgag atagcataaa
     4081 ttgtaaaaag atatacatcg tctcctttaa tatcttctgg taaagaaact tgaaaacatt
     4141 gaacttcatc atttaatttc tcaaactcaa tagcaggctt tatctttggc aatctagcaa
     4201 gaacatcccc agagacatca ttctgtaaca cctccctttt aaactgcgaa aaagcaacca
     4261 gtgaactact aggtacttca tcaataacta tctttttttc gtacagttga tatactgtat
     4321 ctccaagttt atttaatgat gatgcatcaa tagaatgata tggaaaataa aatcttactt
     4381 ttttatctct tgttcccacc acaataattg gaataggaat cacttctata ttatctaata
     4441 ttccttgtaa ttctaactct gttggtaaat tatttagtac aataatatta ggtgagtaat
     4501 ctccttcatt cacaatacct atgctaaatc gagtttgctc cttttcgaca acaagtctaa
     4561 atatatcaat tttatagctt aaatatttaa taatatggtg cagcttattc aattctaaat
     4621 aagtcacttc ttccagtgct aaattaaaac caataacacg attttgattg tttttataaa
     4681 gtctcttttg tgtcgggcta ggagtaataa tatttttcaa ataacgataa ttcatttttg
     4741 tgagattata ctctaaatta accaagtcat gttctttagt aaaactatcg tttggctcag
     4801 ttgaacgttc ttgaaaaaat gatttatttc taatatagtc cacaatcgaa tctacactct
     4861 ttagcctata aaaatcattt tctttaattt caatatcaaa gatatcctca atctctaaat
     4921 aaaatctaac taattctaac gaatccaaat ctgtgatatc aactctttca aatttagata
     4981 gtacatctaa aatatttttt ctaacatcat ctccttgttg actttgtttt ttataataat
     5041 atatctcaag catttttgga acatccaact ttctattctg attgagataa taactctcaa
     5101 ctttaactac cgtcggattt aagtaactag gtaaacttct aataatatct tctttaatat
     5161 tcaaatcggc ttcataaaat acgacaagtt tcttcttata aaaaacaact cgtgatgatt
     5221 taactgattt aagtttatct acaatagatt ttacctcatc taattcaata cgaataccat
     5281 ttacttggac ttggctatct attcttgaac taaataccaa gttatctcct tggtaataaa
     5341 cgtagtcccc cgttacatag tacctatttg aacctatcaa cttaaactta gctttattta
     5401 attcgggttg tagtctatac ccttccgtta ctccattacc accaattaga agttctgcca
     5461 tcttagaatt ctctttttga gaagctatct ttagttgaac cccaggcaaa ggcttaccaa
     5521 ttggaacagt attatatttt ctatctttca actcatagta ggttgcataa attgttgttt
     5581 ctgaaggccc atataaatta aatactcgac acccttgctg aataagccct ctcaacctat
     5641 tcgctaatga actaggaaat gtctcacctg ctagacacaa cgctcttaaa ttctggaata
     5701 cttctggccc actaatatca ataatagttt cagcaaaaga cggagataat gataaatgag
     5761 ttatcttctt tttctcaatt gtttctccta gtcgaataat attctgaatc ccaccatcgt
     5821 aacaaaccaa agtaccaccc gtatatacag gtgccaaaat ctctgttaat gaaacatcaa
     5881 aagtataggg agttgtaaat aaaaattttg attcggaagt aaacttcaca attttataaa
     5941 attcttttac aagccaatct atgttatcat cagttaaaaa tactttttta ggaaccccag
     6001 tagttccaga agtacagata atatgtgcaa tttcattctc tttagttgta gctacttctt
     6061 gatactcact gtaactttct aattttttgg gtaagagcaa aagagttact gaatgatttt
     6121 caagtttaac atccctatca cttatcaaca cgtcaaagac aacttcgcta atacgttcta
     6181 atgatatttt gacctcaaga ctatttgtta taggtaacgg aattttaccc gatttcatta
     6241 tccccaaaac aactggtaaa acatacttat ttttttctat ataaaaaggt acagtctctt
     6301 catcgctatt gagtagtagc tgcttagcaa taaaattaga catcacatct acttcttgaa
     6361 aagtaaactc tcctccgcta tacataacag caactttaga aggatattgt ttcaccgtat
     6421 cactaaaagt ttttaatatg gtcatttctc ttctccttaa tttgattgat tatgcactgt
     6481 cattcataat ttatccacac acaacaataa gaatttcaaa agcaattttc aaagttggca
     6541 aaaattttac ctttttcatc atttccctct tttatttatc atataataaa caaaggcttt
     6601 tcgtcaccga ctacagttga caaaagagac tttcttattt tttgcttgga actttcaaag
     6661 catctttagt tggaatataa tctttgtttc caaagaattt ttcagccaac ttagccaaag
     6721 taccatcttt ttggagttct tccaaacgtt tgtttacaaa tttttgaaga tctttttgat
     6781 tatctgcgaa caa
//
