LOCUS       gnlProkkaBEJHNKKA_69   12157 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BEJHNKKA_69.
ACCESSION   gnlProkkaBEJHNKKA_69
VERSION     gnlProkkaBEJHNKKA_69
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 09:21:44
            Original ID  :: gnl|Prokka|BEJHNKKA_69
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12157
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..375)
                     /locus_tag="ctg42_1"
                     /transl_table=11
                     /translation="MSILDIHDVSVWYERDNVILEQVDLHLEKGAVYGLLGVNGAGKTT
                     LINTLTGVNRNFSGRFTLCGIEAEAGMPQKTSDQLKTHRYFAADYPLLFTEITAKDYVS
                     FVHSLYQKDFSEQQFASLAEA"
     protocluster    1..12157
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[545:2157]"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      546..2157
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /neighbourhood="10000"
                     /product="sactipeptide"
                     /protocluster_number="1"
     cand_cluster    1..12157
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /kind="single"
                     /product="sactipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12157
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="sactipeptide"
                     /region_number="1"
                     /rules="(subtilosin or thuricin or TIGR04404 or
                     Subtilosin_A or skfc)"
                     /tool="antismash"
     CDS             complement(372..533)
                     /locus_tag="ctg42_2"
                     /transl_table=11
                     /translation="MSPAQRRILLYILSFIFVIGAVVYFVKSDYLFTLIFIAIAILFGM
                     RARKADSR"
     CDS             complement(546..1892)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: subtilosin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Subtilosin_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_3"
                     /sec_met_domain="subtilosin (E-value: 0.0, bitscore:
                     1083.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="Subtilosin_rSAM_RRE (E-value: 6e-31,
                     bitscore: 98.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.9e-09, bitscore: 28.4,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-23, bitscore: 75.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 6.1e-12, bitscore:
                     37.5, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.9e-11, bitscore: 36.0,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIEQMFPFINESVRVHQLPEGGVLEIDYLRDNVSISDFEYLDLN
                     KTAYELCMRMDGQKTAEQILAEQCAVYDESPEDHKDWYYDMLNMLQNKQVIQLGNRASR
                     HTITTSGSNEFPMPLHATFELTHRCNLKCAHCYLESSPEALGTVSIEQFKKTADMLFDN
                     GVLTCEITGGEIFVHPNANEILDYVCKKFKKVAVLTNGTLMRKESLELLKTYKQKIIVG
                     ISLDSVNSEVHDSFRGRKGSFAQTCKTIKLLSDHGIFVRVAMSVFEKNMWEIHDMAQKV
                     RDLGAKAFSYNWVDDFGRGRDIVHPTKDAEQHRKFMEYEQNVIDEFKDLIPIIPYERKR
                     AANCGAGWKSIVISPFGEVRPCALFPKEFSLGNIFHDSYESIFNSPLVHKLWQAQAPRF
                     SEHCMKDKCPFSGYCGGCYLKGLNSNKYHRKNICSWAKNEQLEDVVQLI"
     CDS             complement(2026..2157)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     sactipeptide: Subtilosin_A"
                     /gene_functions="biosynthetic-additional (sactipeptides)
                     predicted sactipeptide"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg42_4"
                     /sec_met_domain="Subtilosin_A (E-value: 1.1e-30, bitscore:
                     97.4, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
     CDS_motif       complement(2128..2157)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MKKAVIVENK"
                     /locus_tag="ctg42_4_sactipeptide"
                     /aSTool="sactipeptides"
                     /tool="antismash"
     CDS_motif       complement(2026..2127)
                     /prepeptide="core"
                     /locus_tag="ctg42_4_sactipeptide"
                     /peptide="sactipeptide"
                     /predicted_class
                     /score="29.00"
                     /molecular_weight="0.0"
                     /monoisotopic_mass="0.0"
                     /core_sequence="GCATCSIGAACLVDGPIPDFEIAGATGLFGLWG"
                     /aSTool="sactipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKAVIVENK"
                     /leader_location="[2127:2157](-)"
     CDS             2470..2898
                     /locus_tag="ctg42_5"
                     /transl_table=11
                     /translation="MKQETPITLHVKSVIEDDGNQEVIEFRTTGFYYVKQNKVYLSYYE
                     EHDLGKVKTIVKVSEGEVLVMRSGAVKMNQRFITGASTIAKYKMSFGELELKTSTKSIQ
                     SDLDEEKGRISIAYDMHVGDEQEHLHNMTITYEGGTHA"
     CDS             2895..4565
                     /locus_tag="ctg42_6"
                     /transl_table=11
                     /translation="MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGD
                     YSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLI
                     PSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDV
                     SREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRF
                     VNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALRE
                     KGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWG
                     ADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEE
                     VGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKP
                     AADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEK
                     VIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM"
     CDS             4659..5888
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 105.5; E-value: 4.2e-32)"
                     /gene_kind="transport"
                     /locus_tag="ctg42_7"
                     /transl_table=11
                     /translation="MIRLIIESLKGASQMINRQHIQLSLQSLSLVAGFMVWVLISSLIS
                     QITLDIHLSKGEISLVTAIPVILGSLLRIPLGYLTNRFGARLMFMVSFILLLFPVFWIS
                     IADSLFDLIAGGFFLGIGGAVFSIGVTSLPKYYPKEKHGVVNGIYGAGNIGTAVTTFAA
                     PVIAQAVGWKSTVQMYLVLLAVFALLHVLFGDRHEKKVKVSVKTQIKAVYRNHVLWFLS
                     LFYFITFGAFVAFTIYLPNFLVEHFGLNPADAGLRTAGFIAVSTLLRPAGGFLADKMSP
                     LRILMFVFAGLTLSGIILSFSPTIGLYTFGSLTVAVCSGIGNGTVFKLVPFYFSKQAGI
                     ANGIVSAMGGLGGFFPPLILASVFQATGQYAIGFMALSEVALASFVLVIWMYWQERMKT
                     HTERNSQSIN"
     CDS             5987..6703
                     /gene_functions="regulatory (smcogs)
                     SMCOG1133:Transcription regulator, crp (Score: 123.5;
                     E-value: 1.2e-37)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg42_8"
                     /transl_table=11
                     /translation="MNFLSVRPSDSDLISSDLHELLESISTKRKMEKHTYLFREGMDAE
                     ELYLIQSGLIEIGKLTSDGKDLTLRICQKHDIVGELTLFTEEPRYMLSAKVLEDGEVLV
                     INKNKLEKELIQNGALTFEFMKWMSTHLRKIQSKIRDLLLHGKKGALYSTLIRLSNSYG
                     VERSDGILINIVLTNQDLAKFCAAARESINRMLGDLRKKGVISIDESGKIILHKRDYLR
                     CEIECENCPLEICNID"
     CDS             complement(6734..7453)
                     /locus_tag="ctg42_9"
                     /transl_table=11
                     /translation="MKALIPKQHGAWAMLLIPFLLGMVKGGPVIWHIPLFLGWLFLYLA
                     VYPVTLALKKKQSKPYQKWMCYYGFPACCFLMISVFHKPPLIWVGVSLLPLFLIHMYFA
                     RRKNERALLNDVAGVLFFCSGGFASCWLGMGTLDGWAWFIFLQSALFFIGSSFYVKSVI
                     RERKNRAFAYWSWGYHLLLPFLSALFGAGWAFLAFIPSSLRAWFFHGRDWPVKTIGILE
                     IVNACFFLAVMCLFITR"
     CDS             7597..8073
                     /locus_tag="ctg42_10"
                     /transl_table=11
                     /translation="MNQCDYLLFLKQLPMFNEVPLSIVETLLKNSTFIRGSCDQSPSFL
                     HSQSVYIVLKGSVRFMDTRLPEGSKTVALWEKGDVFPIDEKGGLYLSPFISVNATSDIL
                     ILNIPYYIFKKMMSYHPQLQMNFLAMLQQNVFCSYQLFLRYLHTSQDENAEPGS"
     CDS             8292..11978
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1134:flavodoxin (Score: 80.1; E-value: 1.9e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg42_11"
                     /transl_table=11
                     /translation="MKKKKMSPLFRRLNYFSPIEHHSNKHSQTTREDRDWENVYRNRWQ
                     YDKVVRSTHGVNCTGSCSWNIYVKNGIVTWEGQNLNYPSTGPDMPDFEPRGCPRGASFS
                     WYIYSPLRVKYPYVRGVLINLWREALQTHQNPLEAWKSIVENPEKAKSYKQARGKGGFV
                     RAEWPEVLKLISASLLYTVMKYGPDRNVGFSPIPAMSMISHASGSRFMSLIGGPMLSFY
                     DWYADLPPASPQIWGDQTDVPESSDWYNSGYIITWGSNVPLTRTPDAHFLAEARYKGAK
                     VISISPDFAESSKFADDWLSIRQGTDGALAMAMGHVILQEFYVNQETERFIEYAKQYTD
                     FPFLVTLSKENGVYTAGRFLHAKDIGRKTKHDQWKPAVWDEQTSSFAIPQGTMGSRWDG
                     QQKWNLHMIDEETGEPIEPRLSVLGIEDEIGTVRIPYFSNDGNKVLERDLPIKKMNLSG
                     EETYITTVFDLILANYGVNRGIGERSAVSYDDPEPFTPAWQEQMTGIKKEAVVKIAREF
                     AQNAIDTDGRSMIIVGAGINHWFNSDTIYRAVLNLVLLVGAQGVNGGGWAHYVGQEKLR
                     PAEGWQTIATAKDWEGVPKLQNGTSFFYFATDQWRYEDQPISDLASPIAASSRFKHHAD
                     YNVLAARLGWLPSYPTFNQNGIDLYKEAEKAGAETPEDVGAYVASQLQEKKLKFAIEDP
                     DNEVNFPRNLFVWRANLISSSGKGHEYFLKHLLGTTNGLMNDDSDSIRPEEIKWREQAP
                     EGKLDLLINLDFRMAGTALYSDIVLPAATWYEKHDLSSTDMHPFIHPFAPAISAPWESK
                     SDWDIFKALSKAVSDLAEEVDMEPVKEVVATPLLHDTMQELAQPFGKINDWSKGECEAI
                     PGKTMPNIQVVERDYKHIFHKMTALGPNVALKPSGTKGMSWSIADEYESLKKRLGEITS
                     DSVAKGCPNISEAKQAAEAILTLSSTSNGKVAVKAWESLENITNLKLKDLAEEREEECF
                     TFEQITAQPKTVITSPAFSGSEKGGRRYSPFTTNVEKLIPWRTLTGRQSYYVDHELMME
                     FGETMATFKPILQHRPFLSRRPDQEGKEIVLNYLTPHNKWSVHSMYFDSLPMLTLFRGG
                     PTVWMNKDDAEDTDIKDNDWIECFNRNGVVVARAVLSHRIPKGMAFMHHAQDRHINVPG
                     TKLTNNRGGTHNSPTRIHVKPTQMIGGYAQLSYGFNYYGPTGNQRDLNVVIRKLKEVDW
                     LED"
ORIGIN
        1 ggcctcggcc aaactggcaa actgctgctc tgaaaaatcc ttttgataaa gcgaatggac
       61 gaaagacaca tagtccttcg ccgtaatttc tgtaaatagc agcggataat cggcggcgaa
      121 gtaacggtga gtcttcagct gatctgatgt tttctgcggc atgccggcct ccgcttcaat
      181 tccgcacagt gtaaagcgcc cgctgaaatt gcggttcacg cctgtcagcg tattaatcag
      241 tgtcgttttt ccggcgccgt ttaccccaag caacccgtaa acggcgcctt tttctaaatg
      301 taaatccact tgttctaaga tgacgttgtc ccgttcatac caaacggata catcgtgtat
      361 atccaaaatg ctcatcgcga gtcagccttc cgcgcgcgca tcccgaacag aatggcaatg
      421 gcaatgaaaa tcagcgtaaa cagataatcg cttttgacaa aatagacgac tgcgccgatg
      481 acaaagataa atgaaaggat atacagtaaa attcttcttt gtgctggtga caaatcgttt
      541 ccctcctaaa taagctggac cacgtcttct aattgttcat ttttcgccca agagcaaatg
      601 ttttttcggt gatatttgtt agagttcagc ccttttaagt aacagcctcc gcaatagccg
      661 ctgaacgggc atttgtcttt catgcaatgt tcgctgaacc gcggcgcttg cgcttgccac
      721 agtttatgga cgagagggga gttaaagatg ctttcatagg aatcatgaaa aatatttccc
      781 aatgaaaatt cctttggaaa gagggcgcaa ggacgtactt cgccgaacgg gctgatcaca
      841 atggacttcc agccagcgcc gcaatttgcc gcgcgttttc tttcataggg aataatcgga
      901 atcagatctt taaactcatc aatcacattt tgctcgtatt ccataaactt gcggtgctgc
      961 tcggcgtctt tcgttggatg gacaatatcc ctgcctcttc cgaaatcatc aacccaattg
     1021 taagagaacg ccttcgcccc gagatcccga accttttggg ccatatcgtg gatttcccac
     1081 atgttttttt cgaagacaga catagcgact ctgacaaata taccgtggtc actcaacaat
     1141 tttatcgttt tacaagtttg ggcaaaagag ccttttctcc ctctaaagga gtcatggacc
     1201 tcggaattga cactatcaag agaaatgccg acgatgattt tttgcttgta agtcttcaaa
     1261 agctccaggc tctcttttcg catgagtgtt ccgtttgtta agacagcgac ttttttgaac
     1321 tttttacaca catagtcaag aatctcattg gcgtttggat ggacaaaaat ttctccgcct
     1381 gtgatttcgc atgtcaatac accgttatca aacagcatat cagccgtttt tttgaattgc
     1441 tcaatcgaca cggtgccgag cgcttcaggt gagctttcca aataacagtg ggcgcatttc
     1501 aaattacagc ggtgcgtcag ttcaaaggtg gcgtgcaggg gcatcggaaa ttcattgctt
     1561 ccgctcgtgg tgattgtatg gcggcttgcc cggtttccaa gctggatcac ctgcttgttc
     1621 tggagcatgt tgagcatgtc gtaataccaa tctttatggt cttccggtga ttcatcatac
     1681 actgcacatt gctcagctaa aatctgctca gctgtttttt ggccatccat gcgcatgcag
     1741 agctcgtaag ccgttttgtt gagatccaaa tactcaaagt cagaaatgga gacattatcg
     1801 cgcaagtagt cgatttctaa cacgccgccc tcaggaagct ggtgaactct tacactttca
     1861 ttaataaatg gaaacatctg ctctataaac aaaataccat cccctataca tatgattcaa
     1921 atgaaaaacg gttgtgtatg tatatccaag aggtagattt tagttaaaaa ttgtaattta
     1981 cttaaaaagg gcatagtaga atgactatgc ccttttggga gatccttacc cccatagacc
     2041 gaatagacct gttgcaccgg caatttcaaa atcagggata ggaccgtcca ctagacaagc
     2101 ggctccgatc gagcatgttg cacaaccttt gttttctaca atgacagctt ttttcataat
     2161 tgaatcctcc ctttttttgt ttttctagca gatctatgtt gtacttttat cttaaaacta
     2221 tcaaattact aattcaatac atatattttg aaaaaaatgt gaaaaggaaa tgatagattt
     2281 cggaaaaatg taacatttcc taaaggtaat tagtgatatg attttctctt ctatataagg
     2341 aaatgctttt tatgaggttt atcttcaaat ctgatgagca atgatggtaa gatagaagca
     2401 gttgaagttt acaaaccgaa tgattatact attcaagtca aagtggaatg atgaaaagga
     2461 cgtgtcagaa tgaagcaaga gacaccgata acactccatg tgaagtctgt gatcgaggat
     2521 gacggaaacc aagaagtcat cgaattccgc accaccggat tttactatgt aaaacaaaat
     2581 aaagtgtatc tatcttatta tgaagaacac gacttaggca aagtcaaaac gattgtgaaa
     2641 gtaagcgaag gcgaagtcct ggtcatgagg tcaggcgctg tcaaaatgaa tcagcgtttc
     2701 ataacgggag cttccacaat tgctaaatat aaaatgtcat ttggtgagct tgagctgaaa
     2761 acaagcacaa aatcgattca atctgatctc gatgaagaaa aaggccgtat cagcatcgca
     2821 tatgacatgc atgtcggaga cgagcaggag catttacata atatgacgat cacgtatgag
     2881 ggaggaactc acgcatgaac attgcggaac aaatgaagga cgtgctgaaa gaagaaatca
     2941 aagcggccgt tctgaaagcg ggactggctg aagaaagcca gattcccaat gttgttttag
     3001 aaacaccgaa agataaaaca cacggcgact actcaacgaa tatggcgatg cagttggcaa
     3061 gagtggcaaa aaaagcgccg cgtcaaatcg ctgaagagat tgtcgctcat tttgataaag
     3121 gaaaggcttc gattgaaaaa ctggatatcg ccggcccggg ttttatcaat ttctatatga
     3181 acaatcaata tttaacaaag ctgattccgt ctgtactgga agcaggggaa gcatacgggg
     3241 aaacgaacat cggaaacggt gaacgagttc aggtagaatt cgtatcagcg aatccgacgg
     3301 gagaccttca cctcgggcat gcgcgcgggg cggctgtcgg cgattccttg tgcaacgtgc
     3361 tttcaaaagc gggttacgat gtaagccgcg aatactacat taacgatgcg ggaaaccaaa
     3421 tcaacaatct ggcgctttct gttgaagtcc gttactttga agcgctcgga ttggaaaaac
     3481 cgatgccgga ggatggctac cgcggcgagg atatcattgc gatcggaaag cgtctcgctg
     3541 aggaatacgg tgatcgtttc gttaacgaag aggaaagtga acgcctcgcg tttttccgtg
     3601 aatacggcct gaaatacgag ctggaaaagc ttcgcaagga cttggaaaac ttccgtgtgc
     3661 cgtttgatgt gtggtattca gaaacttcac tgtaccaaaa tggaaaaatt gacaaggcgc
     3721 ttgaagcgct ccgcgaaaaa ggccatgtct atgaagaaga cggcgcgact tggttccgtt
     3781 ccacgacttt cggcgatgat aaagaccgcg tattgatcaa gaaggacggc acgtacacgt
     3841 accttcttcc tgatatcgcg tatcataagg acaagcttga ccgcggcttt gataagctga
     3901 tcaacgtttg gggcgccgat caccacggct acatcccgcg tatgaaagcg gcaatcgaag
     3961 cgctgggcta tgaaaaagga acgcttgaag tagaaatcat tcagctcgtt cacctttaca
     4021 aaaacggcga gaaaatgaaa atgagcaaac ggaccggtaa agccgtaacg atgcgtgacc
     4081 tgattgaaga agtcggcttg gatgccgtgc gttacttctt tgctatgcga agtgcagaca
     4141 cccatatgga ttttgactta gatcttgctg tatcaacatc taacgaaaac cccgtgtatt
     4201 atgcacaata cgcgcatgcc cgtatttgca gcatgcttcg ccaaggggaa gagcagggac
     4261 ttaaaccggc ggcagatctt gatttcagcc atattcaatc agaaaaagaa tacgatctgc
     4321 tgaaaacgat cggcggcttc ccagaggcag tggcggaagc agcggaaaaa cgaattccgc
     4381 accgtgtcac taactatatt tatgatctgg cttctgctct gcacagcttc tacaacgcag
     4441 agaaagtcat cgaccctgaa aatgaagaga aaagccgcgc gcgcctggct ttaatgaagg
     4501 caacgcaaat tacgctgaac aatgcgcttc agctgatcgg cgtatcggct ccggaaaaaa
     4561 tgtaatcacg atcaaaagga caaagtcttc gggctttgtc ctttttttat gagaaaaacg
     4621 tgtgatgtaa ttcacaatcc tgtttggcga gtttttgtat gataagactg attattgaat
     4681 cattgaaagg ggcaagccaa atgatcaacc gtcaacacat tcaattatcg ttacagtcat
     4741 taagcttggt ggcagggttt atggtttggg tgctgatttc atcactcatt tcccaaatca
     4801 cattagatat tcatttaagc aagggtgaga tttctttggt gacggcgatt cctgtgatcc
     4861 tcgggtcgct tctccgcatt cctttagggt atttaacgaa caggtttggc gcgcggctca
     4921 tgtttatggt cagcttcatc ctgcttttat ttcctgtatt ttggatcagt atcgcggatt
     4981 ctctgtttga tttaatcgca ggcggctttt tcttagggat cgggggagcg gtgttttcca
     5041 ttggggtgac ctccctcccg aaatattatc cgaaagaaaa gcacggtgtc gtcaatggga
     5101 tttacggtgc aggaaatatc gggacagccg ttacgacatt tgcagcgccg gttatcgctc
     5161 aagccgtcgg gtggaaatca accgtgcaga tgtatctggt tttgctggct gtctttgcct
     5221 tactgcacgt gttgtttggc gacaggcatg agaagaaggt caaagtttct gttaagactc
     5281 aaatcaaagc cgtttaccga aatcatgtgc tatggtttct gagcctgttt tattttatta
     5341 cgttcggtgc ctttgtcgcc ttcactatct atctgccgaa ctttctggtg gagcattttg
     5401 ggctgaatcc tgcagatgcc ggcttgcgga cggctggctt tattgcggtt tctacgctgc
     5461 tcaggcctgc gggcggattc ctggctgata aaatgagccc gctccgcatc ttgatgtttg
     5521 tttttgccgg gcttacatta tcaggcatta tcctatcgtt ctcgccgaca atcggccttt
     5581 atacgtttgg atcattaacc gtggccgtct gctcaggcat aggaaacggg actgttttta
     5641 aactggtgcc tttctatttt tcgaagcaag cgggaattgc caatgggatt gtgtctgcca
     5701 tgggcggatt aggcggcttt tttcctccgc tcatattggc gagtgtattt caggcaacag
     5761 gccagtacgc gatcgggttt atggcgcttt cagaggtggc gttagccagc tttgtccttg
     5821 tcatatggat gtattggcag gaaagaatga aaacacacac ggagagaaac agccagagca
     5881 tcaactaaca ctggggcatt cacaagattg ttagtttttt ctcgatgggt acaaatcaat
     5941 tcacgttaca ataaacacac aacgtgactt tcttcgaggt gagctcatga attttctctc
     6001 tgttcgacca tctgatagtg atcttatatc cagcgatctg catgaattgc tggaatcgat
     6061 cagcacgaaa agaaaaatgg aaaaacacac gtatttgttt cgagaaggaa tggatgcaga
     6121 agagctttat ctgattcaat caggactcat tgaaatcggc aagctgacat ctgacggaaa
     6181 agacctgacg cttagaatct gccaaaagca tgatatcgtc ggagaattaa cacttttcac
     6241 tgaagaaccg aggtatatgc tcagtgcaaa agtgctagag gatggcgagg tgctcgtcat
     6301 taataaaaat aagctggaaa aagaattaat ccaaaatggc gctttgacat ttgagttcat
     6361 gaaatggatg agcacgcacc tccggaagat tcagtccaaa atcagggatc tgcttcttca
     6421 tggcaaaaag ggggcgctct attccaccct tatccgttta tcaaacagct acggagtgga
     6481 gcgaagcgac ggcattctga ttaacattgt cctgacaaat caggatttgg caaagttttg
     6541 cgcggctgca cgggaaagca tcaaccgtat gctgggagat ctccgcaaaa aaggggttat
     6601 ttcgatagac gaatccggaa aaattatttt gcacaagcgg gactatttac gatgtgagat
     6661 tgagtgtgaa aattgcccgc tggagatttg caatattgac tgaaaaaaca aggacagtgg
     6721 tgtccttgtt tttttacctt gtgataaaca ggcacatgac ggcaagaaag aagcaggcat
     6781 tcacgatttc cagaatgcca atcgttttta cgggccaatc ccttccatga aaaaaccatg
     6841 cccgcaagct gctcgggata aaagcgagaa acgcccatcc tgctccgaaa agagcggata
     6901 aaaaggggag cagcaggtga tatccccatg accagtatgc aaatgccctg ttttttctct
     6961 cgcggatcac cgatttcaca taaaaggaac tcccgataaa aaataaagca gactgcaaga
     7021 aaataaacca agcccagccg tcaagggttc ccatccccag ccagcagctc gcaaacccgc
     7081 ccgaacaaaa gaacaagaca cctgcaacat cattcaataa ggctcgttcg ttttttctgc
     7141 gggcaaaata catatgtatg agaaacagcg gcagtaaaga aacgcccacc cagatgagag
     7201 gcggcttatg aaagaccgag atcatcaaaa agcagcaggc gggaaaaccg taataacaca
     7261 tccacttttg atatggtttg ctttgtttct tttttaaggc aagcgtaacg ggataaaccg
     7321 ctaagtatag gaaaagccaa ccaaggaaga gcggaatatg ccaaataacg gggcctccct
     7381 tgaccatgcc gagtaaaaat gggatcagca gcatcgccca cgccccgtgc tgcttcggaa
     7441 tcagcgcctt catcgaaatc ctcctttttt ctttcattat aaatgcattc accctcctga
     7501 taagtgacat tcatcataca ggctgtgaaa tacatcactg ctgtacaggc tcagtcgagc
     7561 tacactaaag ctatccttag cacaggaggt tttcctatga atcagtgtga ctatttatta
     7621 tttctgaaac aacttcctat gtttaatgaa gtgcctctat ccattgtcga aaccttgctg
     7681 aaaaacagca cgtttatccg cggttcatgt gatcagtctc catcttttct tcattctcaa
     7741 tctgtttata ttgtattaaa aggcagtgtc cgttttatgg acacaaggct ccctgaaggg
     7801 tcgaaaaccg ttgcgctgtg ggaaaaaggc gatgtgtttc cgattgatga aaaaggcggg
     7861 ctttatttat cgccctttat ctcagtcaat gccacttcag acattctgat tctcaacatc
     7921 ccatattaca tatttaagaa aatgatgtct tatcatccgc agctgcaaat gaactttttg
     7981 gctatgcttc agcaaaatgt tttttgttcc tatcaattat ttttgcggta tctgcataca
     8041 tcacaggatg aaaacgccga gcccggttct taaatagagc cggttttttt tgatctttga
     8101 atgaaaggcg gctaatgacc caagcgtcct gcctgaacgc agccttcctc acatcttgtg
     8161 aaaatccttc cttctccttt gtgtgaacat tttgtgaaaa aagcagagtg tgtgacatag
     8221 ttcacaagga aacgcgctgt ctctgtttat agtgaactta gcatcacctg actcggaagg
     8281 agtgaactct catgaagaaa aagaaaatga gtccgttgtt taggagattg aattatttct
     8341 ctcctatcga acaccattca aataaacata gccaaactac ccgcgaggat cgcgattggg
     8401 agaatgtata cagaaacaga tggcagtacg acaaagtcgt tcgctccacc cacggcgtca
     8461 actgtacagg gtcttgcagc tggaatattt atgtgaaaaa cggaattgtc acgtgggaag
     8521 ggcaaaattt gaattatcca tcaacaggcc cggatatgcc tgattttgaa ccgagaggct
     8581 gcccgcgggg ggccagtttt tcatggtata tctacagccc gctccgtgtg aaatatccat
     8641 acgtgcgcgg tgtgctgatc aatttgtggc gggaggcatt gcagacgcat caaaatccat
     8701 tggaagcctg gaaatcgatc gtcgaaaacc ctgaaaaagc gaagtcctat aaacaggcga
     8761 gagggaaagg cggttttgtg cgcgctgaat ggccggaggt gctgaagctg atttcagcct
     8821 ctctgctgta tacagtgatg aaatacgggc ctgaccgaaa cgtcggtttt tctccgattc
     8881 cggccatgtc catgatcagc catgcatcag gctcccggtt tatgtcgtta atcggaggcc
     8941 ctatgctcag tttttatgac tggtatgcgg atcttcctcc ggcatccccg caaatttggg
     9001 gtgaccagac ggacgttccg gaaagcagtg attggtacaa ttccggctat atcatcacat
     9061 ggggctccaa cgttccgtta acgagaacgc ctgacgcgca ttttttggcg gaggcccgct
     9121 ataaaggcgc taaggtcatt tcgatcagtc cggattttgc ggaatcctca aagttcgcgg
     9181 atgactggct gagtattcgc caagggactg acggggcgct tgcgatggcg atgggtcacg
     9241 ttattctgca ggaattttac gtgaaccaag aaactgaacg ttttattgag tacgcgaagc
     9301 aatacactga ttttccattt ctcgtcactc tgtcaaaaga aaatggcgta tacacagcgg
     9361 gacggtttct gcatgcgaag gacatcgggc ggaagacaaa gcatgatcag tggaagcctg
     9421 cagtttggga tgaacagaca agttcatttg ccatacccca agggacaatg ggctcgcgct
     9481 gggacgggca gcagaaatgg aacctgcaca tgattgatga agaaaccggg gaaccgattg
     9541 aaccccgtct ctctgtgctg ggaatagagg acgaaatcgg cacggtgcgc atcccgtatt
     9601 tttcaaatga cggaaacaaa gtgctcgagc gggatcttcc tattaaaaaa atgaacctga
     9661 gcggtgaaga aacgtacatc acgaccgtgt ttgacttgat actggctaac tacggcgtga
     9721 accggggcat cggcgaacga tcggctgtct cctatgatga tcctgagccg tttacgcctg
     9781 cctggcagga acaaatgaca ggaatcaaaa aagaagctgt cgttaagatt gccagagagt
     9841 ttgcccaaaa tgcgatcgat acagacggcc ggtccatgat tatcgtaggg gccggcatta
     9901 accactggtt caactccgac acgatctacc gagcggtgtt aaatcttgtt ttacttgtag
     9961 gcgcccaagg cgtaaacggc ggaggctggg cccattatgt ggggcaggaa aagctccgac
    10021 ctgctgaagg gtggcagacg attgcaactg caaaggactg ggagggcgtg cctaagctgc
    10081 aaaacggcac ctcatttttc tactttgcga cagatcagtg gcgttatgag gaccagccga
    10141 tcagtgattt ggcatcaccg attgctgcgt catcccgctt caagcaccac gctgattaca
    10201 atgtgctggc cgcgcggctg gggtggcttc cgtcttaccc gactttcaat caaaatggca
    10261 tcgatctgta taaagaagct gaaaaagcag gggcagaaac acctgaagac gttggtgcgt
    10321 acgtggcctc acagctccaa gagaaaaaac tgaaattcgc gattgaagat cccgacaatg
    10381 aagtgaattt tccaagaaat ctcttcgtat ggcgggcaaa tctgatctca agctcaggaa
    10441 aagggcatga atattttctc aagcatttgc tggggacgac gaacggttta atgaatgacg
    10501 atagcgacag catccgccct gaagaaatca aatggcggga gcaggcgccg gaaggaaagc
    10561 tcgacttgtt aatcaatctt gacttccgaa tggccggtac ggcgctgtat tccgatatcg
    10621 tgctgccggc ggcgacatgg tatgaaaaac acgatctcag cagcaccgat atgcatccgt
    10681 tcattcatcc atttgctcct gcgatctcag ctccatggga atcgaagtca gactgggata
    10741 ttttcaaggc gctgtcaaaa gccgtttccg atctggcaga agaagtcgat atggagcccg
    10801 tgaaagaagt ggttgcgaca ccgctgctcc acgacaccat gcaggaattg gcccagccat
    10861 tcggcaaaat caatgactgg agcaaaggcg aatgtgaagc cattccgggt aaaacgatgc
    10921 cgaacatcca agtcgtcgaa cgggattaca aacacatttt tcataaaatg actgcacttg
    10981 gtccgaacgt tgctttaaag ccgagcggaa caaaagggat gagctggtca atagccgatg
    11041 aatatgaatc actcaaaaag agactgggag aaatcacatc ggacagcgtg gcaaagggat
    11101 gtccaaatat aagtgaagca aagcaggcag cagaagcgat tttaacccta tcatccactt
    11161 cgaatggaaa ggtcgccgtc aaagcatggg aatcacttga aaacatcacg aacctgaagc
    11221 tgaaagacct ggcggaagaa cgcgaggaag aatgctttac gttcgaacaa attacagccc
    11281 agccgaaaac ggtgatcacg tctccagcgt tttccggctc tgaaaaagga gggcgcaggt
    11341 attcgccgtt tacaacgaat gttgaaaaat taattccgtg gcggacgctg acaggcagac
    11401 aatcctatta tgtcgatcat gaactgatga tggaattcgg tgaaacgatg gcgacattca
    11461 aaccgatcct ccagcatcgc ccgtttctaa gcaggcggcc tgatcaagag ggaaaagaaa
    11521 tcgtcctcaa ttatttgacg ccgcataata aatggtctgt ccacagcatg tattttgatt
    11581 ctctgccgat gctgacgctg ttccgcggcg ggccgaccgt gtggatgaat aaagatgatg
    11641 ccgaggacac ggatatcaaa gacaacgatt ggattgaatg ctttaaccga aacggtgttg
    11701 tcgtcgcgag agcggttttg tctcatcgga ttcctaaagg aatggcgttt atgcaccatg
    11761 cccaagaccg ccacatcaac gtgcccggca caaagctgac gaataaccgc ggcggcaccc
    11821 ataacagccc gacaaggatt cacgtcaagc cgacacagat gatcgggggc tacgcccagc
    11881 tcagctacgg ctttaattat tacggtccaa cggggaatca gcgcgacctg aatgtcgtca
    11941 tccgcaagct gaaggaggtc gattggcttg aagattaaag cgcaaatcgg tatggtcatg
    12001 aacttggata aatgcatcgg ctgccacacg tgcagcgtca cctgcaaaaa cacgtggaca
    12061 aaccgttccg gtgcggaata tatgtacttc aataatgtag aaacaaagcc gggcatcggc
    12121 tacccgaagc aatgggagga ccaggacaaa tataaag
//
