LOCUS       gnlProkkaDGJKGDJM_18   13114 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DGJKGDJM_18.
ACCESSION   gnlProkkaDGJKGDJM_18
VERSION     gnlProkkaDGJKGDJM_18
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 09:05:50
            Original ID  :: gnl|Prokka|DGJKGDJM_18
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13114
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13114
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1560:8205]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1561..8205
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..13114
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13114
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(390..1544)
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 58.3; E-value:
                     1e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg18_1"
                     /transl_table=11
                     /translation="MEDKFLESSEFYSARFRNFSTMIIIPFTILLLAVVIFSFFGKKEI
                     TIQGAGTLEALGNNPVIQSTVNSPIEKNYLKEGKYVKKGDTLLVYNNVSIQDKGKLYNS
                     QKEILDRQLAALNLLKQGVQDNHDSFGEDDEFGYRNDLKSYLQQRNTYLTENTMIQDKS
                     KNDKAKQSSINNELKKQGASSTSIAEFDSSKYNIEINNQKMSDLQSSKLSSIDQEIIKI
                     KQNISELNANIDENNNTNREYKLKAVRDGILHINDEYSESHYISAGANLAQILPILKNQ
                     KTLKVKAYISTVDISSIKVGQKVRFKVTRNVPKPIILTGKIYKISISPVEIGKENYYQI
                     EAKTDIENTNKDLLKYGMQGRMVVITGKTTFFEYYKNKLFNIKQ"
     CDS             complement(1561..3720)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 315.6; E-value:
                     1.1e-95)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_2"
                     /sec_met_domain="Peptidase_C39 (E-value: 1e-43, bitscore:
                     138.7, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1079.3,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRKYRKDYVPQVDESDCGVASLAMILKHYGSALSLAYLRNIAKT
                     TMEGTIALGLVKTAQALGMETQAVKADMSLFEMKDITYPFIVHVVKEETLLHYYVVLKA
                     TPRYILIADPAPDVGITKMSYERFEKEWTGITLFIVPGIEYKPTKETRQSLISLFSKLF
                     KQKQLIVNIVLAALLITIISILGSYFLQGIIDTYIPNGMHSTLAIIALGLLVIYVFNSI
                     FTYARDFLLAILGQRLSIEIILSYIRHIFELPMEFFATRKTGEIVSRFNDASKIIDALA
                     STVVSIFLDVSIVVIMGIILAIQNLKLLGITLISLPIYTIIILTFTKAFERLNNKQMES
                     NAILSSSIIEDIQGIETIKALNSEQMRYRKIDSQFVDYLRKSLAYIKTDSLQQALKLFI
                     QQTLNVIVLWLGANLVISNQLSIGQLMTFNALLSYFVNPLQNIINLQPKLQSARVAHNR
                     LNEVYLVESEFKDRKAVHDVTQLQGNIIVQDVDYRYGYGENVLDKVNLTLKQGEKLTIV
                     GMSGSGKSTLVKLLVNFFAPVSGSIKLNNHDINNIDKHTLRSYINYIPQNPYIFAGTIE
                     DNLRLGNRSNVTDEDILMACKIAMIDTDIAKMPLQLKTELDENANILSGGQKQRITIAR
                     ALLSPAQVLIFDESTSGLDAITEKKLIDNLMKLKSKTIIFIAHRLSIAKRTNNILVLDS
                     GKIVEKGRHDELLAKKGYYYNLVNS"
     CDS             3943..4167
                     /locus_tag="ctg18_3"
                     /transl_table=11
                     /translation="MFKRVWNGWLDGRLNNFFSYVWILILLIMGLVNATKITPITSEKF
                     IINLISVLLIIFLVLLKLQKERRNTHEKL"
     CDS             4154..4333
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_4"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.4e-13,
                     bitscore: 41.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFESLTVNELQNIYGGTNWKKIGKCYAGTLGSAVLGFGAMGPV
                     GYWAGAGVGYASFC"
     CDS             complement(4962..5756)
                     /locus_tag="ctg18_5"
                     /transl_table=11
                     /translation="MEEYGIIICDDEKDQVRRIHDLVKYAIWSLEDSADSKDKKFKITL
                     KANSYIEVADYLEDNKVDSGVYFLDIELSKDKADRDGIDLAEFIRQKDPNAQIIFITAY
                     ENLAAMTYRRRTGALDFITKNDSDEVLQKRLNETLSLAARRIRESHAIKKMTFSYKMGR
                     RIINENINDVLYIITTPKSHRLKIVTVNGMGEFTGDIKKLEAENDFLEKISQSCLANPG
                     NIVEINLSTRIISFKDGYKETFPRRSKVKMKSLIKKYNLKTD"
     CDS             complement(5770..7059)
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="MVNLNSTSGYIVATLILFINTFCRYSFFYLLTPTRKSKKYNLLFI
                     LLTFPVILLINGVGDIIGFFAPFIEIFIFYIVYRQLTLDYRLCGRLLMLDLFSYITFGA
                     SALFFTLFTNYYTMVSVIILDVSLNIFEYIILTKTTIIEKLDDEYGLLYFYLILYIWIS
                     SMVIYYLTTYVFNIDAVSYIIAMVVVVSQLFFSLFVYSINKKIRQDKLSLQQINDLKIY
                     TQQLESSQRSLRKFKHDYQNMLLSLKLSAKKSHDKELIDKLAEYSSKTLEDKVLWQFND
                     VDNVKDELLKSLFISKLNRIFQNNIQYSFECRIVIENLSNKYNSFDIVRILGIVYDNAI
                     EESLEFGDEAKIDTMIYQENGELEIEIRNRYRDTDLTIQDMKKSGFTTKKNHDGLGLAN
                     IEELSQSYNDIFINYQIKDGWFTFLMVMSI"
     CDS             complement(7059..7175)
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="MKFEVLTEKKLQKIAGGATKKGGFKRWQCIFTFFGVCK"
     CDS             complement(7273..7437)
                     /locus_tag="ctg18_8"
                     /transl_table=11
                     /translation="MIFWVTLAVPYIIFISIYTSKKEDGHYRLFDEKVIKKNKKISYVV
                     AIVLRISSK"
     CDS             complement(7537..7809)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_9"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.3e-13,
                     bitscore: 39.1, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFKFYILVLWLLLVMRGDIIMSYEKLNNEELSKILGGNGINWGA
                     VAGSCASGAVIGAAFGNPLTGCVANSAFSFSWQAFKNRPRPKKIA"
     CDS             complement(7767..7946)
                     /locus_tag="ctg18_10"
                     /transl_table=11
                     /translation="MIFWVTVIVVYSIFISIYTSKKEDGHYKLFDEKAIKKNKKISYKR
                     AWILNFIYWFYGFY"
     CDS             complement(7963..8205)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_11"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 4.4e-15,
                     bitscore: 46.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKEFTILTECELAKVDGGYTPENCAMAVGGGMLSGAIRGGMSGT
                     VFGVGTGNLAGAFAGAHIGLVAGGLACIGGYLGSH"
     CDS             complement(8211..8468)
                     /locus_tag="ctg18_12"
                     /transl_table=11
                     /translation="MLKKLWETWLDGGFIRGKKRYVIAPVIWALLIPLGIWLFGNEGMS
                     YLDYIQTPKMIIVTIFCLIGGSTLLYLLDTAMKVNKHMKG"
     CDS             complement(8598..8771)
                     /locus_tag="ctg18_13"
                     /transl_table=11
                     /translation="MNNNFVQVDKKELAHIIGGRNSYDYIDSGQFGYDIGCTIANTKFF
                     KRLRHSNQNICS"
     CDS             9003..9266
                     /locus_tag="ctg18_14"
                     /transl_table=11
                     /translation="MNSFSNNINFSKISVSLITLLLLIWTLVDGNLIHLGILAFSSLVT
                     TMLHFHYFEATDDKHPLNRIDFGLQLLFIFISIIKFFLISGR"
     CDS             complement(9305..9634)
                     /locus_tag="ctg18_15"
                     /transl_table=11
                     /translation="MKAIYKGKEVQIWQISKTAEQPEWIKAAFKANYLKWSGDKLLFIM
                     NGVKAPVKISAWTNFKTLFNGASGWWATYASGYIGDYLDFTNRKIISERKFKKKYKIVD
                     TYVNK"
     CDS             9856..10830
                     /locus_tag="ctg18_16"
                     /transl_table=11
                     /translation="MRYIKFTLLIYSFLLTWGITTNSISADEVTPTTTSETTVTPQSQS
                     TSVDSNDEDAAIEEKFYSHDVTIDEYNQNVANFNKVNTDTVKTMVTENSNNLDQVLYIG
                     RPTCYFCRQASPHLRDFNQLINNQLYYYDIDAEPSAHDFAFKEIGIPGTPTTMRLKNGK
                     VVSAWIGGEKTGQEFYDFLFSADANKLADSYTIKKTVSTDTSNPVITNNQNVEPTVKHI
                     PTNISQLKEEKTTTELVNTTSQPFKPVKKIQNPATTTNKKNKNSVLPQLGVVPLYHQPL
                     FKLPIPKIPKQLERTIMLITFLVLYLGFLICLWLSWKEINKRK"
     CDS             complement(10993..11643)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 126.7; E-value: 1.6e-38)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_17"
                     /transl_table=11
                     /translation="MIKVAIFDLDGLLVDTEIVSLKIYQELLSEYGYSFTKEEYAKHYS
                     GKTEKENIKRFIDTYNLSVSYQECLDEVLNIERKLISQGVELKVGVKSLLMYLKENNYK
                     VTLATSSTKDRAISILKGHDILSYFDEFVFSEDVTLSKPNPEVFLKACEKTNVSTNEAI
                     VLEDSENGIMAAYNAHIPVICIPDMKRPAKEYLEKTIAVCKTLNDVIDYLKTK"
     CDS             complement(11754..12095)
                     /locus_tag="ctg18_18"
                     /transl_table=11
                     /translation="MKAIYRGRKVDVWQVSRDNVQPDWVKDAFEHDGLRWLHGSGNKVR
                     IYWPAVTRAKKGIIRTILNGISASFVSIAGGSASMYDIGFEGDVIDFTNSKVVTAEKFA
                     KKYRIVSED"
     CDS             complement(12116..12445)
                     /locus_tag="ctg18_19"
                     /transl_table=11
                     /translation="MFVLKCHNSIIMAKIENRWWNDGLFSIKVIIWIFFITSAILEVNY
                     KKKYGELDKRARKQATLGTFLIVTTIFDEGYENKILYIIVLIALLVYIVLVIYRLVMAI
                     KDRKK"
ORIGIN
        1 agcttgagga taacctccct aataacttta atccaattat acattctgac caaggatggc
       61 actactaatt agaatattac cgtgaaaaga ttgattcctt aggtttaatt caaagtatgt
      121 cccgcaaggg aacctgccta gataatgccc caatggaaag ctttttccat ctttttaaag
      181 ttgaatcaca gcctgaaata aagaaatgta agagtatttc tcagtttaca catttcttta
      241 acaagtatgt caattggtac aataatgacc gaatttccaa taaaacaaaa aacatgagtc
      301 cggttgatta ccgaacccat gtcttagctg cttaaaaata ttttattttt gtctaacttt
      361 tttgttgcna aggaatattc aaaaaaattt tattgtttaa tgttaaataa cttattctta
      421 taatattcaa aaaatgttgt cttacctgta attacaacca ttcgcccttg cataccatac
      481 ttcaataaat ccttattagt attttcaata tctgttttag cttcaatttg ataataattt
      541 tcttttccta tctctactgg agaaatcgat atcttatata tttttccagt caaaataata
      601 ggtttaggta cgtttctagt tactttgaat cttacttttt gccctacttt tatggaagaa
      661 atatctactg tacttatata tgcctttact tttaaagttt tttgattttt caaaattggc
      721 agtatttgag ctaaattagc ccctgcactt atataatgac tttcactata ctcatcgtta
      781 atatgtaaaa ttccgtctct aacagccttt aacttatatt ctctgttagt attattgttt
      841 tcatcaatat tagcgttcaa ttctgaaata ttttgcttaa tttttataat ttcttgatca
      901 atagaactta acttacttga ctgtaaatca ctcatttttt gattgtttat ctcaatattg
      961 tacttagacg aatcaaattc agctatactt gtagaggatg caccctgttt tttcaactcg
     1021 ttattaatcg aactttgttt tgctttgtcg tttttagatt tatcctggat cattgtattt
     1081 tctgttaaat acgtattcct ttgttgtagg taactcttta aatcattacg gtaaccaaat
     1141 tcatcatctt ctccaaaaga atcatgattg tcttgaacac cttgtttaag taagttcaaa
     1201 gctgccaact gtctatctaa gatttctttt tgtgaattat acagcttccc cttatcttgt
     1261 atactcacat tattataaac aagtaatgta tctccttttt ttacatactt tccctctttt
     1321 aaataatttt tttcaatagg actatttaca gttgattgaa taacaggatt gtttcccaat
     1381 gcctcaagcg ttcctgcacc ttggatagtt atctcttttt ttccaaaaaa gctaaaaatt
     1441 actaccgcca acaataaaat tgtaaaagga ataataatca tagttgaaaa gtttctaaat
     1501 ctagctgaat aaaattcgct gctttctaaa aatttatctt ccataataca atactccccc
     1561 ctaactatta actaaattgt agtagtatcc ttttttagct aataattcat catgtctacc
     1621 cttttctaca atttttccgc tatctaatac tagaatatta tttgttcgct tagctataga
     1681 taatctatgt gcaataaaaa ttatagtttt tgactttaat ttcattaaat tatcaattag
     1741 ttttttctcc gtaatggcat ctaatccact tgtagattca tcaaaaatca atacttgtgc
     1801 tggagataat aaggctctag caattgtaat tctttgtttt tgtccacctg ataaaatatt
     1861 agcattttca tctagttcag ttttcaattg tagtggcatc ttcgctatat ctgtatcaat
     1921 cattgctatt ttgcaagcca tgagaatatc ctcatcagtc acattagatc gattacctag
     1981 tctaagatta tcttctattg tcccagcaaa aatatatgga ttctgtggta tgtaattaat
     2041 ataagaacgc aaagtatgct tatcaatgtt atttatatca tgattattta gttttatact
     2101 acctgaaact ggggcaaaaa aattcaccaa tagtttaact aacgttgatt tgccagagcc
     2161 actcatacct actatagtta gtttttctcc ctgttttaaa gtcaaattaa ccttatccaa
     2221 aacattttca ccatatccat agcgatagtc aacatcttga actataatat ttccttgaag
     2281 ttgagtgaca tcatgaacag cttttctatc tttaaattca ctttcaacta agtaaacctc
     2341 attcaaacga ttgtgagcta cccttgcact ctgcaatttt ggctgtaaat ttatgatatt
     2401 ttgtaacgga ttcacaaaat aacttaatag tgcgttaaaa gtcattaatt gtcctataga
     2461 gagttgatta ctaattacca gatttgcccc taaccatagg actataacat ttaatgtttg
     2521 ttgaataaat aactttaatg cttgttgcaa cgagtctgtt tttatatatg ctaacgattt
     2581 acgcaaatag tccacaaatt gactatcaat tttgcggtaa cgcatttgtt cgctgtttaa
     2641 ggcttttatt gtttctattc cttgaatatc ttcaataata gatgaactaa gtatcgcatt
     2701 actttccatt tgtttattat tcaatctttc aaatgccttt gtaaatgtaa gaataataat
     2761 cgtgtaaatt ggaagtgaga taagagttat tcctagtaat ttaagatttt gaatagccaa
     2821 gattattccc ataataacta caatacttac atctaaaaaa atagatacca cagtacttgc
     2881 taaagcatct ataattttac tagcatcatt aaaacgagag actatttctc cagtttttct
     2941 ggtcgcaaaa aattccatag gcaactcaaa aatatgtcta atataactta aaataatttc
     3001 aatcgaaagt cgttgcccta aaattgctaa taaaaaatcc cttgcatatg taaaaattga
     3061 attgaacaca tatattacta gtaatcccaa agcaataatt gccagtgtac tatgcatacc
     3121 attaggaata tatgtatcaa ttattccctg taaaaaatat gatcccaata tactaataat
     3181 tgtaattaac aaagctgcca atacaatatt aactattagt tgcttttgct taaataattt
     3241 actaaatagt gatattaatg attgtctagt ctcttttgtc ggcttatatt caattcctgg
     3301 aacgatgaat aaagtaattc ctgtccattc tttttcaaaa cgttcatacg acattttagt
     3361 tatccctaca tctggagctg gatcagcaat taaaatatat ctaggcgttg ctttcaatac
     3421 tacataataa tgtaataacg tttcttcttt aaccacatgt acaataaatg ggtatgtgat
     3481 gtctttcatt tcaaaaaggg acatatcagc ttttacggct tgtgtttcca ttcctaaagc
     3541 ctgtgctgtc ttaacgagac ctaaagctat agtcccctcc attgttgtct tagcaatgtt
     3601 ccttaaatac gctaatgata gcgctgatcc atagtgtttc aaaatcatag ccaacgaagc
     3661 tacaccacaa tcagattcgt ctacttgtgg gacgtaatct tttcgatact ttcttagcaa
     3721 gaaaaatccc ccttttatta ctactcttat attaaagata tcatttctta ttatcctatg
     3781 tattagttat caaatttggt aacttttact acatatctgg cgataattcc atttaggaaa
     3841 aaaatacacc atttacgcta aaataatttt ttcaacgtaa aatattctat actaattata
     3901 gagagcaacg ttgcataata ttgtagaaag gatgtgattt aaatgtttaa gagagtatgg
     3961 aatgggtggt tggatgggag attaaataac tttttttcat atgtatggat actaatatta
     4021 ctgataatgg gattggttaa cgcaactaaa atcactccca taacatcaga aaaatttatt
     4081 attaatttaa ttagtgtttt actgataata ttcttagttt tactaaaatt acaaaaagag
     4141 aggagaaata ctcatgaaaa actttgaatc tttaactgtt aatgaattac aaaatattta
     4201 tggtggtact aattggaaaa agattggtaa atgttatgct ggaactttag gaagtgctgt
     4261 actcggcttt ggcgctatgg gtcctgtagg ctattgggca ggtgctggcg ttggttatgc
     4321 tagtttttgc taatatgatg caagtactct atagtaagag aatatgaatt tatgagaatc
     4381 cacctatatc ataaatagct ataggtggat tttattatag aagaactagt tatttaagct
     4441 tttagtattt tccataataa tcactcgctt tctgtttagt atttttctaa ctctataatg
     4501 acagaactgt ggttattatg gaattttttt aatttttttc acatagaaaa taaaaaatcc
     4561 tatggattca atattaggaa tccacaggat tttaaaaaga gccgaagaac tagggtattg
     4621 taaaaaattt tattatgttt ttaggttgat gagtatgcta aagcgtacga aaatcgagta
     4681 gtagaaggca gttaaattaa tcaaccacct actactgctc gatttcagat aagatctcct
     4741 cgatgtagca taaattattc ttattttaac atctcgctat agtacgttta cattatagaa
     4801 accctacaac taacaatata ataataccta ttttaccgta ttcgctcacc atttataact
     4861 aacgtctcaa tttagtagat atcttgtttt gtcgtcacta gaggcaaaac actctacaat
     4921 ttgagtttct actaaaaaag cagtttagct atatactaat cttagtctgt tttcaagtta
     4981 tattttttaa tcaaactttt cattttaact ttacttctcc taggaaaagt ctctttatat
     5041 ccatctttaa aagaaataat ccttgttgat aaattaattt caacaatatt acctggatta
     5101 gctaaacaag attgtgatat tttttctaga aaatcatttt ccgcttctaa cttcttaata
     5161 tcacccgtaa actcacccat accattaact gtaactattt tcaatctatg tgacttaggt
     5221 gtggtaataa tatataaaac atcattgatg ttttcattaa taattcttct gcccatttta
     5281 taactaaatg tcattttctt tatggcatga gattccctaa ttctccttgc agctaatgat
     5341 aaagtctcat ttagtcgctt ttgaagcact tcatcactat cgtttttagt aataaaatcc
     5401 aatgctccag tacgacgtcg ataagtcatt gctgctagat tttcataagc tgtaataaaa
     5461 attatctgtg catttggatc tttttgtcta ataaattcag ctaaatctat cccatctcta
     5521 tctgctttat ctttactaag ttcaatatct aaaaaataaa ctccactatc tactttgtta
     5581 tcttccaaat aatcggctac ttcaatataa ctattagctt tcaaagttat tttaaatttt
     5641 ttatctttac tgtcagcaga gtcttctaaa gaccaaatag catatttaac tagatcatgt
     5701 atccttctaa cttgatcctt ctcatcgtca caaataataa ttccatattc ttccaaatta
     5761 aactacccct taaatgctca taaccataag gaaagtaaac caaccatctt taatttgata
     5821 attgataaaa atatcattat aagattgact taattcttct atattagcta atcctaatcc
     5881 gtcatgattc ttcttagttg taaagcctga ttttttcata tcttgaattg ttagatcggt
     5941 atctcgataa cgatttctaa tctcaatttc aagttcacca ttttcttgat aaatcatagt
     6001 atctatctta gcttcatcac caaactcaag actttcttca attgcattat cgtacacaat
     6061 tcctaatatt ctaacaatgt caaacgagtt atacttattc gacaagtttt ctatcacaat
     6121 tcgacattca aaagaatatt gaatattatt ttgaaagatt ctattcaact tactgataaa
     6181 tagactcttt aataactcat ctttaacatt gtcaacatca ttaaactgcc ataatacttt
     6241 atcttctaaa gtcttacttg aatattcagc tagtttatct attaactctt tatcatgact
     6301 tttttttgca ctgagtttca agcttaatag catattttga taatcgtgct taaatttacg
     6361 taaacttcgc tggctacttt ctaactgttg tgtataaatt tttagatcat taatttgttg
     6421 taaacttaat ttatcctgcc gtattttctt attaatggaa tatacaaata atgaaaagaa
     6481 caattggcta acaacaacta ccatagctat aatatacgat actgcatcta tattaaatac
     6541 atatgttgtt agatagtaaa taaccattga actaatccat atgtataaaa ttaaataaaa
     6601 atacaataat ccatactcat catctagttt ctctattata gtcgtctttg ttaaaattat
     6661 atattcaaaa atgtttaatg acacatctaa tattatcaca ctgaccattg tgtaataatt
     6721 tgtaaataat gtaaaaaata atgctgaagc accgaatgtt atgtaggaaa ataaatctag
     6781 cattaacaac cttccacata atctgtaatc caaagttagt tgtctgtata caatataaaa
     6841 aataaaaatt tcaataaatg gtgcaaaaaa accaataata tctccaacac cattaattaa
     6901 aagaattaca ggaaaagtaa gaagtataaa taataaatta tacttcttac ttttcctagt
     6961 aggggtcaaa agataaaaaa aactatatct acagaaagta tttataaata aaattagtgt
     7021 agctactata taaccagatg ttgaatttaa attaaccatt atttacaaac accaaaaaat
     7081 gtgaatatac attgccatct tttaaagcca ccctttttgg ttgctccccc agctattttc
     7141 tgtaacttct tttctgttaa cacttcaaac ttcataaaaa atctctcctt tgttatcttt
     7201 attacaaata tagtttaaca ttttttaatc tactttattc gtttttttat catattcggt
     7261 tcattttaat gcttatttgg atgaaattct taaaactata gccaccacat aacttatttt
     7321 cttattcttt tttataactt tctcatcaaa taacctgtaa tgcccatctt cttttttact
     7381 agtatagata ctgataaaga taatatacgg aactgctaat gtaacccaaa atatcatgtg
     7441 tcctcctcat tatcagaata attttacctt attaaaaaat agcgtcaaac ataacttatt
     7501 agcttttatt tgacgctatt ctataaaaat ttataattac gctatttttt taggacgagg
     7561 tctattttta aatgcttgcc aactaaaaga aaaagctgaa ttggctacac aacctgttaa
     7621 tggattaccg aaagctgcac ctataaccgc accactagca caactacctg cgactgctcc
     7681 ccaattaatg ccattccctc ctaaaatttt agaaagttcc tcattattta atttttcata
     7741 actcatgatt atatctcctc gcatcactaa taaaagccat aaaaccaata tataaaattt
     7801 aaaatccatg cccttttata acttattttc ttattctttt ttatagcttt ctcatcaaat
     7861 aacttgtaat gtccatcttc ttttttacta gtatagatac tgataaagat actatataca
     7921 actattactg taacccaaaa tatcatttta atcattccta gtttaatgac tgcctaaata
     7981 tcctccgata caagccaatc cacctgctac taaacctata tgtgcaccag caaatgctcc
     8041 cgcaagatta cctgtgccta ctccaaatac agttcctgac attcctcctc tgattgcacc
     8101 agatagcatc ccaccgccta ctgccattgc acagttttca ggcgtatagc caccatcaac
     8161 ttttgctaac tcacattctg tcaatattgt aaattccttc atcatgataa tcatcctttc
     8221 atatgtttat ttaccttcat tgcagtatct aataaataaa gtagtgtact accacctatt
     8281 agacaaaaaa tagtaactat tatcatttta ggcgtctgga tataatctaa ataagacatt
     8341 ccctcattac caaacaacca tattcctagt ggaatcaata gtgcccaaat aactggagca
     8401 ataacatatc tcttctttcc tctaatgaat ccaccatcca accaagtctc ccatagtttt
     8461 tttagcatgt aaaaacacat cctctctaaa acacttgtga aacatatact tacactttta
     8521 ttgtattatc attccgtatt caaatatcga tttagcgtaa aatacgttat tctataccta
     8581 gttggttaca tttcttttta actacaaata ttttgatttg agtgtcttaa tcttttgaaa
     8641 aatttggtat tagcgattgt acatcctata tcataaccaa actgtccgct atctatataa
     8701 tcataagaat ttcttccacc aattatatgt gccaattctt tcttatcaac ttgtacaaaa
     8761 ttattattca taacttcaac acctcataat tttaaaaatt tattatagct ataatttaca
     8821 cttataatta ttcacttcat ctgctctttt tgactatttc ttctaatttt gctaaatttt
     8881 attcttattc tcttttttca accagatagg caccacttat taccaaattg gaaaaatctc
     8941 ctcaatttat taccttctat gtaataataa aaatactttt ataatgaatt gaggtaaaaa
     9001 ttatgaatag tttttctaat aatattaatt tcagcaaaat ttctgtttca ctaattactt
     9061 tactcctatt gatctggaca ttagttgatg gaaatctaat tcatcttggt atactagcct
     9121 tttcttcttt ggttacaacc atgctacatt tccattattt tgaagctact gatgacaagc
     9181 atccactaaa tagaattgat tttggattac aattgctatt tatctttatt tctattatta
     9241 aatttttctt gatttcagga agataacaat aagcctatca ggtatcaaat tacatctgat
     9301 aggcttattt attaacatat gtatcaacaa ttttgtactt ctttttaaat tttctttctg
     9361 atataatttt tcgattagtg aaatccaagt aatcgcctat atacccactt gcataagttg
     9421 cccaccaacc tgaagctcca ttaaataaag tcttaaagtt cgtccaagca ctaattttaa
     9481 caggtgcctt aactccattc ataataaata acaatttatc acctgaccac tttagatagt
     9541 tagctttaaa tgctgctttt atccattcgg gttgttctgc tgttttactt atctgccata
     9601 tttgtacttc tttaccttta tagattgctt tcatagaaat caccttctac atataattaa
     9661 agagctctat taattacatc ttcattatac tattttcata atacatccaa tgctaaattt
     9721 cttaactagc actatttctt acttatttgg taaatagtcc aaataagtag ttattgctac
     9781 cattccagca gtttatcaca ctatgtagac attatttgca ataattacat atatacgatt
     9841 agggggattg aaaaaatgag atacattaaa tttactttac taatatattc ttttttacta
     9901 acttggggaa tcaccacgaa tagtatatca gcggatgaag ttacacctac tacaacatcc
     9961 gaaacaacag ttacgcctca aagtcaaagt acatctgttg attctaatga tgaagatgct
    10021 gcaattgaag aaaaatttta ctctcatgat gttacaatcg atgaatataa tcaaaatgtg
    10081 gcaaacttca ataaagttaa tactgatact gttaaaacca tggttactga aaatagcaac
    10141 aatttagacc aagttcttta cattggacgt cctacttgtt atttttgtcg acaagcttca
    10201 ccacacctac gcgattttaa tcaactaata aataatcagc tttactacta tgatattgat
    10261 gctgaaccta gtgctcatga ctttgcgttt aaagaaattg gaattcctgg aacacctaca
    10321 actatgcgtt taaagaatgg taaagttgtc agtgcttgga ttggtggcga aaaaacagga
    10381 caagaatttt atgacttttt attttctgca gatgctaaca agttagcaga ttcctatacc
    10441 ataaagaaaa ctgtaagcac agatacttca aatcctgtta ttacaaataa tcaaaatgtt
    10501 gaaccaactg ttaaacatat accaacaaat ataagccaac ttaaagagga aaaaactact
    10561 actgaattgg ttaatactac ttcacaacca tttaaacctg ttaaaaaaat tcaaaatcca
    10621 gctacaacta ctaataagaa aaacaaaaat tctgttctac cacaattagg ggttgtccct
    10681 ctttatcatc agccattatt taaacttcct attcctaaaa ttcctaagca attagaacgt
    10741 actataatgt taattacttt tctagttcta tatttgggat tcttaatatg tttatggttg
    10801 agctggaaag aaataaataa aaggaaatag ataaaaagta aatatgcgat atagcaatag
    10861 gaccaattag aaaatttatg caaataatcg atttttgtag attcaaaact acatttttgc
    10921 ataaattagt aaattggtcc tatctttata tttaactttt ttaattacac tacttttatt
    10981 atgcggtaac tgttattttg tttttaaata atcaatgaca tcatttaacg tcttacaaac
    11041 agcaatagtt ttctctaaat attcttttgc tggtcttttc atatcaggta tacaaataac
    11101 tggaatatgt gcattatagg cagccataat accattttca ctatcttcta aaactattgc
    11161 ttcattagtt gatacatttg ttttttcaca agcttttaag aaaacttctg gattaggctt
    11221 acttagtgtt acatcttcac taaatacaaa ttcgtcaaag tagctgagaa tatcgtgccc
    11281 ttttaaaata gaaatcgctc tatctttggt acttgatgtt gccaaagtta ctttataatt
    11341 attctctttt aggtacataa gtagagattt tacccctact tttaattcca caccttgtga
    11401 aataagtttg cgttcaatat tcaaaacttc atctaaacat tcctgataag ataccgataa
    11461 gttatatgta tctataaaac gtttaatatt ttctttttct gttttcccac tataatgttt
    11521 tgcatattct tctttagtaa aactatatcc atattcagat aataattcct gatatatttt
    11581 taaagataca atttctgtat ctactagtaa tccatcaaga tcaaatatag ccactttaat
    11641 cacaataaat caaccacctt tcgtaataca tatttattat atcatataat tattcaatct
    11701 tattttgaca taaaagttga ttatcttgtc atagacaatt taataccttt acctcaatct
    11761 tcagacacta tccgatattt cttagcgaac ttttcggctg taacaacctt agaattggta
    11821 aaatcaataa catctccctc aaaaccaata tcatacatcg acgcgctgcc accagctata
    11881 ctaacaaaag aagctgagat accattcaaa atagttcgta ttattccttt ttttgctcta
    11941 gtaactgctg gccaataaat tctgacttta ttaccactac catgtaacca tcgcaaccca
    12001 tcatgttcaa aagcatcttt aacccaatca ggttggacat tatctctact cacttgccaa
    12061 acatctactt ttctacctct atagattgct ttcatttgct ttatcacctt tcttattact
    12121 ttttcctatc cttaatagcc ataactaatc tatatatcac taatactata tataccaaca
    12181 gtgctattaa tactattata tatagtattt tattctcata accttcatca aatattgtag
    12241 ttactattag aaatgttcct aatgttgctt gctttctagc tcgtttatct aattcaccat
    12301 attttttctt ataattaact tccaaaattg ctgatgttat aaaaaatatc caaataatta
    12361 ccttaatact aaataatcca tcattccacc acctattctc tatttttgcc attattatac
    12421 tattatgaca tttcaacaca aacatttata tatcaaggat ctattaaata aacacctaaa
    12481 aagtgcatac tttttgcata ctaagaaagt tcaagaagac tgttagcaaa aaaagacacc
    12541 ttgcctctac tcatataata gtagaaacga ggtgtcttgt attttctaag aataataaaa
    12601 aacctttctg ttggaataac agaaaggagg aaatagatgg taactaacca caacttcttt
    12661 tttgaggtaa ctaacctctt actaacctac tacttaaatt atatagcagc atataaattt
    12721 gtcaataaat cactttaaat atttttttaa cttatatcct agtgtataat gtcttttggt
    12781 atataagatt aactatctta atctgtacca gaattgaggt gtacacctct tgctaaacct
    12841 actacaaatg ttaggactaa ctatcctaac aaatatcata tctgacatta tttcggataa
    12901 gataaaaaat cgctataagc gtaaacatta atctttgacg agtagatcag atacccttaa
    12961 gcagaagcgg tggcaagcaa cccaacttct gctttttttg ctataaaaat aagctcatcc
    13021 aatcctttta aggactagat gagctttatt attatgtctt tagacctggt tgagtacgct
    13081 aaagcgtacg aaacaaaaaa ccactcgcta tgcg
//
