LOCUS       c00023_gnlPro..        17389 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LBLNBGPC_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 10:27:45
            Original ID  :: gnl|Prokka|LBLNBGPC_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 141879
            Orig. end    :: 159268
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17389
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[151879:155010]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13131
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17389
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17389
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             658..939
                     /locus_tag="ctg23_149"
                     /transl_table=11
                     /translation="MKPMYVSINSEKTGANLKSLFKNNGYSVRDIQSVMGFENPQSIYK
                     WLSGRSLPSLDNLVILSKVLHTTIEDILVVDGDVVFLFNLTWTIQLNR"
     CDS             961..1209
                     /locus_tag="ctg23_150"
                     /transl_table=11
                     /translation="MQEVMSYRGYKGTIEYSLEDNILHGEVLGIRSLLSYEGNTLQELK
                     DDFEDTIDDYFECCKNHNMTPEKPYKQNIVINLEPDL"
     CDS             1327..1515
                     /locus_tag="ctg23_151"
                     /transl_table=11
                     /translation="MKKSRVNKIKIESKKALVVRRLDWRAPSSRINYSILEMIDDLNDS
                     KLERASNLAELESLLNK"
     CDS             1924..3558
                     /locus_tag="ctg23_152"
                     /transl_table=11
                     /translation="MKRIKAIITGIFISLTAILLVACGKSTGENSKQVLNLSTTGPLDT
                     IDISKSTGYGQTGNVFESFYRLGKDGKVTPGLAKSGQVSQDGKTWTFTLRDAKWSNGDK
                     ITAQDFVYSWKRTIDPKTASPYAYLFYDVKNAQAINEGKMSADKLGIKAEGDNKVVITL
                     DRPISYFKVLMTYPLFGPQSEKVVQKYGKKYGTNSKYMVYSGPFKVKDWNGTSDKWSFV
                     KNNQYWDKKVVKLQKINYQVVKNTNTGYQLFQQGKLDLTPLSSEQVKNLHNKPEFKQYS
                     YSYVAYLDYNFNDSNEVNRKALNNKNIRLALSLAIDRKTLTKKVFGDGSNVPTGFVASD
                     LATNPKTGKDFAAEQKVDNTVDYNEKLAREYWKKGLQEIGEKNLNFTILASNEMANNDA
                     LTQYLQSQYTKVLPGIKVSVQNIPGNSALSKARKGNYDIYVSGWSGDFKDPITFMQIPV
                     TGTSYNYGKYSNKEYDALIEKAQNEDANDANKRWEDLVKAARLFNADQGVTPLYQQTTS
                     YMQNTKVKGIIQNTAGTQWNYKYAYIK"
     CDS             3821..4600
                     /locus_tag="ctg23_153"
                     /transl_table=11
                     /translation="MSVLEVKDLHVTVEGKKILKGVNLKMSTGEIHAIMGPNGTGKSTL
                     SSTIMGDPAYKITKGDILLNGKSIIDLPVDERARMGLFLAMQYPQEIPGVTNAEFVKSA
                     INARRPKDDPIPLMDFIKRLDETLETLDMSEEMADRYLNEGFSGGEKKRNEIMQMMMIR
                     PEFAILDEIDSGLDIDALKVVSRGVNQMHGDNFGSLIITHYQRLLNYIIPDYVHVMMDG
                     RLVKTGGPDLAIRLEKEGYAKLRDELGLDIKLVDENA"
     CDS             4613..5863
                     /locus_tag="ctg23_154"
                     /transl_table=11
                     /translation="MKQLSIDELIELRKEPEWFKAKRNEAKQLIETTKLPSFQKIKYHD
                     WNINVDGTTAIDNQPEFDTNADVYQYASDKAQIKLPQEFLDKGVIVEDFEDALVNHEDI
                     MKKYFMEKGLKMDDNRLLAEHVANLQSGVLVYVPKNVDLETPLTCEYIQNSRVEGDYVH
                     HVLIVTEANSSLSYVERLKTDGDKSNTANIVVEVIAGNGSRIHFASVDNLSKNTTAYMN
                     RRGYLQRDSKIDWAMGMMNSGLTIGDFDSDLVGDGSHAELKVVGISTSDQIQGIDTRVT
                     NIGKNTIGHILQHGVALDASELTFNGIGHVMKRSKGSDAQQESRILMLSPQARGDANPI
                     LLIDDNDVTAGHAASIGRVNPEQLYYLMSRGLQKRLAEKLVIRGFLAPVLDEIPLKEIR
                     NEFSELIERKVSYDEEN"
     CDS             5850..7076
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_155"
                     /sec_met_domain="Aminotran_5 (E-value: 3.2e-161, bitscore:
                     529.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTSDLRKDFPLLETKMNDQPLTYLDSAATSQKPKQVIDEIADY
                     YNKYNSNIHRGVYNLAVKTTDKYENVRHKVAKFINAYRDEEVLFTKGTTQSLNWIAQGY
                     VRYNLHEGDEIVTTYMEHHSNIVPWQAIAQEKNLKVKYVTLTEEGKLDLDDLKQKITDK
                     TKIVAVTHVSNVLGTINPIKEIAAIVHQSNAILVVDGAQSVPHLPVDMQDLEADFYVFS
                     GHKMLGPTGIGVLWGKYELLEKMHPLEYGGEMIDSVTTEKSTFKEIPWNFEGGTQNIEG
                     VLGLGAAIDYLEEIGMENVARNDEDLQKYALEKLANIKSIEFYGPKDPNQRCGVVSFNL
                     KGIHPHDVATFLDADGIAVRAGHHCAQPLMDWLGVSATLRASFYFYNTYEEIDKLVDSL
                     KKVEEFFQI"
     CDS             7073..7522
                     /locus_tag="ctg23_156"
                     /transl_table=11
                     /translation="MSNLNNLYRQAILEEANHPRHKGKLENKSVEVELRNPTCGDVITL
                     TALIEDNKIKDIAFDGYGCTISQSSASIMTNEVLNKDFDTIKNMVLSFSDMITKEVKPD
                     RKVLGEAIILEGVKQFPARIKCAMLSWKAIYQLIEKYEGKGEKND"
     CDS             7515..8918
                     /locus_tag="ctg23_157"
                     /transl_table=11
                     /translation="MISEDIKDIGGQYKYGFKDDIEPIYTTGEGLSEEVVRNISKAKNE
                     PEWMLDIRLAAYEKYKTLKMANFGPDLSELDLDHINYFRRDTDTVARKWEDVPQEIKDT
                     FDRLGVPEAERKYLAGSSAQYESEVVYHNMKEDFAKKGIIFMDTDSAVQEYPELVKKYF
                     GKLIPADDNKMAALNTAVWSGGTFIYVPKGVKVETPIQSYFRINAGNSGQFERTLIIVD
                     EGASVNYVEGCTAPNYSQDSLHAAVVEVNVLRDAYCRYTTIQNWSNNVYSLETKRARAL
                     ENATMEWVDGNLGSKVTMKYPSIYLDGEGAHGNMLSIAFAGKGIDSDTGARMIHNAKNT
                     YSSTVSKSLCKDGGIADYRGYVRFNRDSDGSFAHVECDTIIMDDESSSDTIPFNEVLNS
                     NVSMEHEAKVSKISEDQLYYLMSRGISEEKATEMIIMGFVEPFTKELPMEYAVELNRLI
                     EYQMDGSVG"
     CDS             9111..9689
                     /locus_tag="ctg23_158"
                     /transl_table=11
                     /translation="LKVTHVLKVKTNFFWDSLNVIRASILGANDGIISVSGIVLGAAGA
                     NLDSKTLLISGLSGMLAGACSMAGGEWISVSTQRDIQEKTMERQLENEDCENCPIKLQK
                     NDILMPFHAAASSFCSFIIGAMIPLLTMILARPEHRVVFTLIAMIASLSINAIVCTHNS
                     EVSTSKTILRNVITGLLTTLVTFILGASV"
     CDS             10001..12268
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_159"
                     /sec_met_domain="Gly_radical (E-value: 5.3e-40, bitscore:
                     129.7, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 6.7e-261, bitscore:
                     860.2, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVEKTQMQNVDVKDAWEGFRGKEWKEEIDIREFIQDNFTPYDGDQ
                     SFLEGPTEATTKLNDKLIDLKLKERAHGGPLEADTKVVSTITSHKPGYLDKSLEKIVGL
                     QTDKPMKRALMPYGGIRMAKGALEAYGFKIDPETDFVFENLSKTHNQGVFDAYTSEIMK
                     ARHNKIITGLPDAYGRGRLIGDFPRIALYGIDRLIEGKKKDLENCGDGEMTNDVIQMRE
                     EISDQIKALNDMKIMAESYGYDISKPATTAKEAIQWLYFGYLASIKQQNGAAMSIGRID
                     SFIDIYIERDMKRGILTEKEAQELIDQFTMKLRMVCFIRTPAYNSLFSGNPIWATLSIA
                     GMGLDGRHHVTKTSYRFLNTLHNMGAAPEPNITLLWSDRLPESFKHYAASVSIASSTIQ
                     YENDDLMMKTWGTDYYGIACCVSAQPIANGMQFFGARANLAKAVLYAINGGKDELTKQQ
                     VGPAYEPISSEYIDYDEFMKKFDDMMEWIADIYVNALNTIHYMHDKYYYESAQMALKDT
                     LVDRSFATGISGLSVAADSISAIKYGHVKVIRDEDGIAVDFKADHDFPRYGNDDDRVDD
                     IAAWLVKELFTKMSKHHLYRGAKLTTSVLTITSNVVYGKNTGTTPNGRQKGEPFAPGAN
                     PAYGADTTGALASLLSVAKLPYKYATDGISNTFAVTPTTLGHDEKMQEDTLVNMIGGYM
                     RKDGHHLNINVFNRDTLLDAQAHPEKYPTLTIRVSGYCVYFADLTKEQQDDVIARTFHA
                     SM"
     CDS             12295..13131
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 70.1;
                     E-value: 7.7e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_160"
                     /sec_met_domain="Radical_SAM (E-value: 2.2e-32, bitscore:
                     106.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSANPLLNPVPTKDGHVVGYVHSLETFGAVDGPGIRFVAFMQGCH
                     MRCKFCHNPDTWKTRVGSQMTTEEVLNKALPYRSFWGDKGGITLSGGEILLQIDFALEL
                     FKMCKEEGISTCLDTCGQPFTRREPWFSKFNELMDYTDILLVDIKHINSDEHKRLTGFP
                     NDNILDMCEYLSSIGKPVWIRHVLIPGITDNDEYLKQLGEYVKENLHNVEKFEVLPYHT
                     MGVHKYQEMGIRYRLEGVEPPTPERVKNAEKLLEVDRYQGYKDWYPGINTLDQQPS"
     CDS             complement(13217..14095)
                     /locus_tag="ctg23_161"
                     /transl_table=11
                     /translation="MYYNAALVLEGGAMRGLYTSGVLDTFLEHDIQFDCVIGVSAGSLN
                     GANFVSKQYQRTYNVNVKYRKDHDYISLARPFKHESIINLDFLFDDHGLDWHNFDNKAY
                     LKSETDFIVVATSLESGKAVTLRNPQPGQDLIDALEASSSMPFISKPHNTSKGLCLDGG
                     IANSIPFDIAQKMGFQKIIVVRTRPRDYRKKPTSFALKRLYSNSFKEYPEFVKTAIRRP
                     EMYNHSVEVLNKLEHNDKIFCLAPNDPVKVGRLEHNTKKMTELYNIGRNDAESNLEAML
                     NYLQKSEPLYD"
     CDS             complement(14353..14655)
                     /locus_tag="ctg23_162"
                     /transl_table=11
                     /translation="MNKIIISKLNNDENKIEWRISNSETGHYLNISISRALEDAMKKKR
                     NLSFNRFESEQINNLSHLVTNIQEDYVLNIDESNISSSYLPLKGIDALSYMKTVE"
     CDS             complement(15262..15651)
                     /locus_tag="ctg23_163"
                     /transl_table=11
                     /translation="MPRPTKDPSTKSYTITVDGIYREWMVSQENKSVSIKNLIKLALEL
                     VGDGDFTEALIKKAASTSAYSEKTSQVISNFNEEKVADTAHQQKLDDVNQKLADLQAER
                     EALLNEKADNSTGIDLSMLSTKFDK"
     CDS             complement(15671..16900)
                     /locus_tag="ctg23_164"
                     /transl_table=11
                     /translation="MSKNNILKLNVANDLGYGSVKAKVEDTNIHFPSVIAIQREQDLNK
                     PVEFNSNQEKLTYLEGMINHMDVTISSSAVKTQGRFLVGNAAIKSSLPLKAFDVNDFTG
                     KSDNDLAIILTLSMIAAQRISLAVKNGEDLSDQLSTEINMTTALPVSEGKKNGIINNYV
                     NKYIGSKHTVVFHNFKDPITVSLSFKNVYVALEGEVAQLYLKNSDIKLQGLIKQDFSKN
                     YPELANDIKVSDLVKIDNLLGIDIGEGTTDLVVIKEGHANAVASTSLPTGYGNALQDAI
                     DVLQTENMNFEARSQLQDYLAQEVSLLAKRMQTKVRQIVFEQLEPFADKIVTAASKTMR
                     KAGANVEILYVYGGGSIPMLEQTALRQKLSQKMKDFSGGIDVPVIWINKSYAQNLNEKG
                     LELILKAMNK"
ORIGIN
        1 aaatcgccca aattaaccta acagtttata gtttaatgac ctaagctttg ttagtatata
       61 agtgtaccga tgaagctagt ggatgaggtg tgacaagccg cctagccata cgtctcttaa
      121 taactactat gacgaaatat acggatacgt ttattttttc taatgtacta attgggagca
      181 acgaaaaaaa gttgtgtaga gagaagcaag gggactcata tctgaaacta agacacttgc
      241 cgtcagggat tcgcaatatg ccatcttcag ttaattaagg ctgattacct taggaaccaa
      301 agaagaatat caactaagaa ttcgtgtcgt gaagttgtgg tgacacagct ataactgacg
      361 agtaaggttt gagtagccaa aatcgacaat attacattaa ctggaacatt gcacatgttt
      421 ggtgaaaatt ggataggaaa aggtctatgc cctgaacttg aaatgcggac taggtcatgg
      481 aagttgctag ccatgatgtg ctagtctgat tcagtagtct aataagtcca gatacaagag
      541 tatcccacgt aagccaatac gcgtcggttt acataatttt tagtcaatgc aaattttgcg
      601 ttggctattt ttggtattaa atgttcgagg tatgtataat taaattgagg tgatttcatg
      661 aagccaatgt atgtttcgat aaattcagaa aaaactggtg ctaatctaaa aagtttattc
      721 aaaaataatg ggtacagtgt acgtgatatt caatcagtta tgggatttga gaacccacaa
      781 tccatttata aatggttatc tggtagatca ctacctagtt tggataactt agtcattctc
      841 agtaaggttc tacataccac aatcgaagac atcctcgttg ttgacgggga tgttgttttt
      901 ttattcaatt taacttggac tatacagtta aatagataat aattgaaagg aaacataaaa
      961 atgcaagaag tcatgagcta tagaggttac aaaggaacaa tagagtattc tttagaggat
     1021 aatattttac atggcgaagt tttggggatt agaagtttat tatcctatga aggaaataca
     1081 ttacaagaat tgaaagatga ttttgaagat acaattgatg attattttga gtgttgcaaa
     1141 aatcacaata tgactcctga aaaaccttac aagcagaaca ttgtaattaa cttagaacca
     1201 gatttgtaag aaaaattata tttatattct gaacttcgtg atgaagatat ttctgacagt
     1261 ataaatagag cgattagaaa tttggtcgac aaataggatg tatactttta cggaaagtga
     1321 tgtattatga aaaaaagtag agttaataag attaagatag aatctaaaaa agctttagtt
     1381 gtgcgtagat tagattggag ggccccttct tctaggataa attattctat cttagagatg
     1441 atagatgatt taaatgattc taaattagaa cgagcaagca atttagctga attagagagt
     1501 ttattaaata agtaatatta tttttaccaa aaattagaaa atacaaactt ataattaaaa
     1561 tttattgaca aaagtatagt aaggttatat gatttggtta aagaaatgag aggagtgtga
     1621 atcactatgt caaactttat caatacacaa tgctgttgtt tggtaacatg ttgtccagta
     1681 ggaaacatgg gttttggcat gcagaaaatt agattcacac ttccaagatt ggattaaact
     1741 gtatatattt attatcggta ccgatgcaga ttaatttaat cagttagatt atatgagata
     1801 ataataactg gacttgcgat tctaattttt tggagttgca agtccttttt gtttatttgg
     1861 aaggatggat gatgaactgt ttatagatta aaaaacatat tttacataaa ggggaaaata
     1921 aagatgaaaa gaattaaagc aattattact ggaatattta taagcttaac cgcaattttg
     1981 ttagttgcat gtggtaaatc aactggtgaa aattctaaac aagttttaaa tctaagtaca
     2041 actggaccat tggataccat tgatatttct aagtctacag gttatggtca aactgggaat
     2101 gtttttgaaa gtttttatcg tttaggtaaa gatggcaagg taactcctgg attagctaaa
     2161 agtggtcaag tttcacaaga tggcaaaaca tggactttta ctttgagaga tgcaaagtgg
     2221 agtaatggag ataagattac tgctcaagat tttgtatatt cttggaaaag aacaattgat
     2281 cctaagacag cttcaccata tgcttatttg ttctatgatg taaagaatgc ccaagctatc
     2341 aatgaaggta aaatgtcagc tgataaatta ggaataaagg ctgaaggtga taataaggtt
     2401 gttattacgt tagatagacc tatatcatat tttaaagtct taatgacata tccattattt
     2461 ggaccacaaa gtgaaaaagt ggtacaaaag tatggtaaga aatatggaac taattctaaa
     2521 tacatggtgt actcaggacc atttaaagtt aaagactgga atggtacttc ggataagtgg
     2581 tcatttgtaa agaataatca atattgggat aaaaaagtgg taaaactaca aaagattaac
     2641 tatcaagtag ttaaaaatac caatacaggt tatcaattat tccaacaagg taagttagat
     2701 ttaacaccat tatctagtga acaagttaag aatctacata acaagccaga attcaagcaa
     2761 tactcttatt cttacgttgc atatttagac tataacttta atgattctaa tgaagtaaat
     2821 cgtaaggcac taaataataa aaatattaga ttagctttat cattagcgat tgacagaaag
     2881 acacttacaa agaaagtttt cggcgatgga tctaatgtac caactggttt tgtagcatct
     2941 gatttagcta ctaatccaaa aacaggtaaa gatttcgctg cagaacaaaa agtagataat
     3001 acagttgatt acaatgagaa attagctaga gaatattgga aaaaaggatt acaagaaatt
     3061 ggtgaaaaga atttgaattt cacaattcta gcttccaatg aaatggctaa taatgatgct
     3121 ttaactcaat atctacaatc acaatataca aaggtattgc caggaattaa ggtttccgta
     3181 caaaatattc ctggaaatag cgcattatct aaagctcgta aaggtaacta tgacatttat
     3241 gtatctggtt ggagtggaga ctttaaagat ccaatcactt tcatgcaaat tccagttaca
     3301 ggaacttcat acaattatgg aaagtactct aataaagagt acgatgcttt aattgaaaaa
     3361 gcacaaaatg aagatgccaa tgatgctaat aaacgttggg aagatttagt taaagctgct
     3421 cgactcttta atgctgatca aggggtaaca cctctatatc aacaaacaac atcttatatg
     3481 caaaatacca aagtaaaggg tattattcaa aatactgcag gtacacaatg gaactacaaa
     3541 tacgcttata ttaaataggt aagaactcgt ctagaatgat ttctaggcga gtttttaagt
     3601 tgtgctaaat aatttgcata agagtattga ttatgttgta tgtaagcgtt attctatatt
     3661 tgtaaactta ttataaagat tattacttaa ttacaaataa atttaaggat atatattgta
     3721 aaaatactta aatctaatcg ttatgttgag taatttgtct tataattatt attgataaga
     3781 aaattccagg aaaggtaact attttatagt ggtgatttaa atgtcagtat tagaagttaa
     3841 agatttacat gtaactgttg aaggaaagaa aatattgaaa ggtgttaatt tgaagatgtc
     3901 aactggtgag attcatgcaa tcatgggtcc aaacggtacc gggaaatcaa cactttcttc
     3961 aactattatg ggcgatcctg cttataagat tactaaaggg gatattttgt taaatggtaa
     4021 aagcattatt gatttaccgg ttgatgaacg tgctagaatg ggactatttt tagcaatgca
     4081 atatccacaa gaaattccag gagtaactaa tgcagaattt gttaagagtg caattaatgc
     4141 tcgtcgtcct aaagatgatc caattccttt aatggacttc atcaaacgtt tggatgaaac
     4201 tttagaaaca ttggatatgt ctgaagaaat ggctgacaga tatttgaatg aaggcttttc
     4261 tggtggtgaa aagaaacgta atgaaattat gcaaatgatg atgatcagac ctgaattcgc
     4321 aattttagat gaaatcgact ctggactaga tattgatgct cttaaggttg tttctcgtgg
     4381 ggttaaccaa atgcatggcg ataattttgg atccttgatc attactcact atcaaagact
     4441 tttaaactat attattccag attatgtaca tgttatgatg gacggtcgtc ttgttaaaac
     4501 tggtggtcca gatttggcaa tccgtttgga aaaagaagga tatgcaaaac ttcgtgatga
     4561 acttggttta gatattaaat tagttgatga aaatgcttag ggggcttgta caatgaaaca
     4621 actatccata gatgaattaa ttgaacttcg aaaagagccc gaatggttta aagctaagcg
     4681 aaatgaagct aagcaactaa ttgaaactac taaattacct agtttccaaa agattaaata
     4741 tcatgattgg aacataaatg ttgatggaac aactgcaatt gataatcaac ctgaatttga
     4801 taccaatgct gatgtttatc aatatgcaag tgacaaagca caaattaaac taccacaaga
     4861 atttcttgat aagggagtaa ttgttgaaga ttttgaggat gctctggtta accatgaaga
     4921 tattatgaag aaatacttta tggaaaaagg actaaaaatg gacgataatc gtctattagc
     4981 agaacatgta gcaaatcttc aaagtggtgt tttagtctat gtacctaaaa atgtagattt
     5041 agaaacacca ttaacttgtg aatatatcca aaattcacga gttgaaggag attatgttca
     5101 tcatgtatta attgttacgg aagcaaatag ttcgctatct tatgtagaac gtttaaaaac
     5161 tgatggtgat aagagtaata cagccaatat tgtagttgaa gttattgccg gtaatggaag
     5221 tcgcattcac tttgctagtg ttgataattt aagtaagaac acaactgcct atatgaatcg
     5281 tcgtggatac ttacaaagag actctaagat tgactgggca atgggtatga tgaattctgg
     5341 tttaacaatc ggtgattttg attctgattt agttggcgat ggctctcatg ctgaattaaa
     5401 agtcgtaggt atttcaacaa gtgatcaaat tcaaggaatc gatacacgag ttacaaatat
     5461 tggaaagaat acgatcggcc atatcttaca acatggtgtt gctttagatg catccgaact
     5521 aactttcaac ggcattggac atgtaatgaa gagaagtaaa ggttctgatg cacaacaaga
     5581 aagtcgtatt ttaatgttat ctccacaagc tagaggggat gctaatccaa tcttactaat
     5641 tgatgataat gatgttactg caggacatgc ggcaagtatt ggtcgtgtaa atcctgaaca
     5701 attgtactac ttaatgagtc gtggcttaca aaaacgttta gctgaaaaat tagtaattag
     5761 aggtttccta gctcctgttt tagatgaaat acctttgaaa gaaattcgca atgagtttag
     5821 tgaattgatt gaaagaaagg taagttatga tgaagaaaac tagtgattta agaaaagatt
     5881 ttcctctttt agaaactaaa atgaacgatc agcctttaac ttacttagat agtgcagcta
     5941 cttcgcaaaa gcctaagcaa gtaattgacg aaattgcaga ctactataat aaatacaata
     6001 gcaatattca tcgcggtgtc tacaatttag cagtcaaaac aactgataaa tatgaaaatg
     6061 taagacataa agtggcaaag tttattaatg cttatcgcga tgaggaagta ctttttacca
     6121 agggaacaac tcaaagtttg aactggatag cacaaggtta tgttagatat aacttgcatg
     6181 aaggcgatga aattgttacc acctatatgg agcatcacag taatattgtt ccatggcaag
     6241 caattgcaca agaaaagaat ctaaaggtaa agtatgtaac tttaactgaa gaaggtaaac
     6301 ttgatttaga tgatttaaag caaaagatta ctgataaaac aaagattgta gcagttactc
     6361 atgtttctaa cgttttagga acaattaatc caattaaaga aattgcagct attgttcatc
     6421 aaagtaatgc aattttagta gttgatggtg ctcaatctgt gccacattta ccagtagata
     6481 tgcaagattt agaagcagac ttttatgtat tttctggcca taagatgcta ggacctactg
     6541 gaattggtgt tctctgggga aagtatgaac tcttagaaaa aatgcatcct ttagaatatg
     6601 gtggagaaat gattgacagt gtaacaactg aaaaatcaac attcaaagag attccttgga
     6661 attttgaagg tggaacacaa aatattgaag gcgtactagg tcttggtgct gcgattgatt
     6721 atttagaaga aatcggaatg gaaaatgtgg ctcgaaacga tgaggactta caaaagtatg
     6781 cactcgaaaa gttagctaat atcaagtcta ttgaatttta tggtcctaaa gatcctaatc
     6841 aaagatgtgg agtagtatcc tttaatttga aaggtattca tcctcatgat gtagcaacct
     6901 ttttggatgc tgatggaatt gcagttagag ctggtcacca ttgtgcacaa ccacttatgg
     6961 attggttagg tgttagtgct actttgagag caagtttcta tttttataat acttatgaag
     7021 aaatcgacaa attagtagat tctctaaaga aagtagagga atttttccaa atatgagtaa
     7081 tttaaataat ttatatcgac aagcaatttt agaagaagct aaccatccac gacataaagg
     7141 taagttggaa aataaaagtg ttgaagttga attgagaaat ccgacttgtg gggatgttat
     7201 taccttaact gcattaattg aggataataa gataaaagat attgcttttg atggctatgg
     7261 ttgcacaatt tctcaatcat ccgcaagtat tatgacaaat gaagtattaa ataaagactt
     7321 cgatacaata aaaaacatgg tattgtcatt ttccgatatg attacaaaag aagtaaaacc
     7381 tgatagaaaa gttttaggtg aggcaataat tttagaaggg gttaaacaat tcccagctcg
     7441 aattaaatgc gcaatgttat catggaaggc aatttatcaa cttattgaga agtatgaagg
     7501 aaagggtgaa aagaatgatt agtgaagata taaaagacat tggtggccaa tataaatatg
     7561 gctttaaaga tgacattgaa ccaatttata caactggtga aggtcttagt gaagaagttg
     7621 taagaaatat ttctaaagct aaaaatgaac ctgaatggat gctagatatt agattggctg
     7681 cttatgaaaa gtacaagact ttgaagatgg ctaattttgg accagatttg tcagagttgg
     7741 acttagatca tattaattat tttagacgtg atactgatac ggtagctaga aagtgggaag
     7801 atgtaccaca agaaattaaa gatacatttg atcgtttggg tgtaccagaa gctgaacgta
     7861 aatatttagc tggttcttct gctcaatatg aatcagaagt tgtttaccat aatatgaaag
     7921 aagactttgc caaaaaaggt atcatattta tggatacaga ttctgcagtt caagaatatc
     7981 cagaattagt aaagaaatat tttggaaagt taatcccagc agatgataat aaaatggcag
     8041 ctcttaatac agctgtttgg tctgggggaa catttattta tgtacctaag ggagtaaagg
     8101 ttgaaacacc tattcaaagt tacttccgaa ttaatgccgg aaattcagga caatttgaaa
     8161 gaacactaat cattgtcgat gaaggtgcta gtgttaacta tgtagaaggt tgtacagctc
     8221 ctaattattc acaagattcc ttacatgcgg cagttgttga agtaaatgtt ttgagggatg
     8281 cttattgccg ttatacaaca atccaaaact ggtccaacaa cgtatatagt ttggaaacaa
     8341 aacgtgccag agctttggaa aatgctacta tggaatgggt agatgggaat cttggttcca
     8401 aggtaactat gaaatatcca agtatctatt tagatggcga aggggcacat ggaaatatgt
     8461 tatctattgc atttgcgggc aaaggtattg actctgatac tggtgcaaga atgattcata
     8521 atgctaagaa tacatattcg tcaactgtat caaaatctct ctgtaaagat ggaggaattg
     8581 ctgactatcg tgggtatgta aggtttaata gagatagtga tggttcgttt gcgcacgttg
     8641 aatgtgacac tatcattatg gatgatgagt cttcaagtga tacaattcca tttaatgaag
     8701 tattaaatag taatgtatca atggaacatg aagctaaagt ttcgaaaatt tcagaagatc
     8761 agctttacta tttgatgagt agaggtattt ctgaagaaaa ggctactgaa atgattatta
     8821 tgggatttgt tgaaccattt actaaagaac taccaatgga atatgcagtc gaattgaata
     8881 gattgattga gtatcaaatg gatggtagtg taggttaatt ataaaaaagc atacttttta
     8941 agtatgcttt tttatattat tgtgaaacgt gtatataatt ataaattttg ctaaattagt
     9001 actaattact catatgatgt ataatttaat cgtgataaaa gcgatttata taatttaaat
     9061 atatatataa aaacggtatt atttttatat ttcgtgagga agtgtacaaa ttgaaagtta
     9121 cgcatgtatt gaaagttaag actaattttt tttgggatag tttaaatgtt ataagggcta
     9181 gtattttagg ggccaatgat gggattattt cagtatctgg aatcgtgtta ggtgctgcag
     9241 gggctaatct tgatagtaag acccttttaa tcagtggttt gtctggcatg ctagctggag
     9301 cttgttcaat ggctggtgga gaatggatat ctgtaagtac tcaaagagat attcaagaaa
     9361 aaacaatgga aagacagttg gaaaatgaag actgtgaaaa ttgtccgata aaattgcaaa
     9421 agaacgatat cttaatgcca tttcatgctg cagccagttc tttctgttca tttataattg
     9481 gggcaatgat tccattattg acgatgatcc tagcaaggcc agaacatcgc gtggtattta
     9541 cattaattgc gatgattgcc tcattatcaa ttaatgcgat agtttgtaca cacaactccg
     9601 aagtttcaac tagcaaaaca attttacgaa atgttataac tggattgtta acgacgttag
     9661 ttacctttat tttaggggca tcagtataaa tacttttaaa gactctatat ctaaattttt
     9721 ttggatatag ggtctttttt tgtaatttta agaaattcta aaataaaatt aatgaaattt
     9781 atattttgat acataaatca catttttaaa gtttataaac tgttgtcaaa aatattgtca
     9841 tattaacatt tataatgatt aaaataaatg atagcgttta taagattttt tgaaaataaa
     9901 aaacattgtg aacgattttt cattgaattt aatttaacta aggtgtagta ttaacagtgt
     9961 agaaaacgtt ttcttaaaaa tcacaaagga ggctttgagt atggttgaaa agactcaaat
    10021 gcaaaacgtt gatgtaaaag atgcttggga aggatttaga ggaaaagaat ggaaagaaga
    10081 aattgatatt cgtgaattta ttcaagataa cttcactcca tatgatggag atcaatcttt
    10141 ccttgaagga ccaaccgaag ctacaacgaa gttaaacgat aaattaatcg acttaaaatt
    10201 aaaagaacgt gcacatggtg gacctcttga agctgataca aaagtagtat caacaattac
    10261 atctcataaa ccaggttatt tagacaagtc attagaaaag attgttggtt tacaaacaga
    10321 taaacctatg aaacgtgcac ttatgccata tggtggtatc agaatggcta aaggtgcttt
    10381 ggaagcttat ggattcaaga ttgatccaga aacagacttc gtatttgaaa atctatctaa
    10441 gacgcataac caaggtgtat ttgatgcata cacaagcgaa atcatgaaag ctcgccacaa
    10501 caagattatc actggactac cagatgcata tggtcgtggc cgtttgattg gagacttccc
    10561 acgtattgca ttatacggta ttgatcgttt gatcgaagga aagaagaagg atttggaaaa
    10621 ttgcggcgat ggtgaaatga ctaacgacgt aatccaaatg cgtgaagaaa tttctgacca
    10681 aatcaaagcc ttaaacgata tgaagattat ggctgaatcc tatggctatg acatttctaa
    10741 accagctaca acagctaaag aagcaattca atggctatac tttggttact tagcatctat
    10801 caagcaacaa aatggtgctg ctatgtctat tggtcgtatc gattcattca tcgatattta
    10861 cattgaacgt gatatgaagc gtggtatttt aactgaaaaa gaagcacaag aattaattga
    10921 ccaattcaca atgaaattga gaatggtatg cttcattcgt acaccagctt acaactcact
    10981 attctcaggt aaccctatct gggcaacatt atcaattgct ggtatgggct tagatggacg
    11041 tcaccatgta actaagacat catatcgttt cttaaataca ttgcataata tgggtgccgc
    11101 accagaacca aatattacat tactttggtc tgatcgtttg cctgaatcat ttaagcacta
    11161 tgctgcaagt gtatctattg caagttctac aattcaatac gaaaacgatg acttaatgat
    11221 gaagacatgg ggaacagact actatggcat tgcttgctgt gtatctgcac aaccaattgc
    11281 aaatggtatg caattcttcg gagctcgtgc aaatctagct aaggctgtat tgtatgctat
    11341 caatggtggt aaggatgaac ttacaaaaca acaagtaggt cctgcatacg aaccaattag
    11401 ctcagaatac attgactacg atgaattcat gaagaaattc gatgacatga tggaatggat
    11461 tgctgatatt tacgtaaatg ctttgaacac aattcattac atgcatgaca agtattacta
    11521 tgaatcagca caaatggcat tgaaagatac attggtagat cgtagctttg ctacaggtat
    11581 ctctggattg tctgttgctg ctgactcaat ttcagctatc aagtacggac atgttaaagt
    11641 aattcgtgac gaagatggta ttgctgttga cttcaaggca gatcatgact tccctcgtta
    11701 tggtaacgat gatgatcgtg ttgacgatat tgctgcatgg cttgttaagg aactatttac
    11761 taagatgagc aagcatcatc tatatcgtgg agctaagtta acaacatccg ttcttacaat
    11821 tacttcaaat gttgtttatg gtaagaacac aggtactact ccaaatggtc gtcaaaaggg
    11881 tgaaccattt gcaccaggtg ctaacccagc atacggagca gatacaacag gtgctttagc
    11941 atcactatta tccgttgcta aattaccata caagtatgct acagatggta tttctaatac
    12001 atttgctgta acaccaacaa cattgggtca tgatgaaaag atgcaagaag atacattggt
    12061 aaacatgatc ggaggctata tgagaaaaga tggtcatcat ttgaatatta atgtattcaa
    12121 cagagatact ttattagatg ctcaagcaca tccagagaag tatccaacat taacaattcg
    12181 tgtttcaggt tactgtgtat actttgctga tttaactaaa gaacaacaag atgacgttat
    12241 tgcaagaacc ttccatgctt caatgtaata attagaagag agtaggtgga gagaatgagt
    12301 gctaatcctt tattgaatcc agttccaact aaagacggtc atgtcgtagg atatgtacac
    12361 tctttggaaa cttttggagc tgttgatgga ccaggtatac gttttgtcgc ttttatgcaa
    12421 ggttgccata tgaggtgtaa gttctgtcac aatccggaca cttggaaaac aagggtaggt
    12481 tcacaaatga cgactgaaga agttctaaac aaggcacttc cttatcgcag cttttggggc
    12541 gacaaaggtg gaataacttt atcaggtggt gaaattctat tgcaaataga ttttgcacta
    12601 gagttattca agatgtgcaa ggaagaaggt attagcactt gtttggacac ttgtggacag
    12661 ccatttacaa gaagagaacc ttggtttagt aagttcaatg agttaatgga ctataccgac
    12721 attttattag ttgatatcaa gcatattaat tcggacgaac ataagagatt aaccggattc
    12781 ccaaatgata atattttgga tatgtgcgaa tatctttcta gtatagggaa acctgtttgg
    12841 attcgtcatg tccttatccc aggcatcacg gataatgatg aatacttgaa acaattgggc
    12901 gagtatgtta aggaaaatct tcataatgtc gaaaaatttg aagtattacc ttatcataca
    12961 atgggcgttc ataagtatca ggaaatgggt atcagatatc gtcttgaagg tgttgagcct
    13021 cctacgccag aaagagtaaa aaatgctgaa aaactgctag aagtagatag atatcaagga
    13081 tataaagatt ggtatccagg cattaatact ttggatcaac aaccaagcta gctaaattgg
    13141 caaatataaa ataaaaacat ggtatcgctt agttttgcta agtagatacc atgttttttg
    13201 gttttaaaat gtatttttag tcatataggg gttcactttt ttgaagatag ttaagcattg
    13261 cttcaagatt actttcagca tcatttctac ctatattata gagttcagtc atctttttag
    13321 tattgtgttc aagcctacca actttaactg gatcattggg tgctaaacaa aaaattttgt
    13381 cgttgtgttc aagtttattt aaaacttcaa cagaatggtt atacatttca ggacgtctga
    13441 tagccgtttt aacgaattct gggtattcct tgaagctatt actgtagagg cgttttaaag
    13501 caaaactagt aggctttttg cgataatcac gtgggcgagt acgaacaact ataatttttt
    13561 gaaaacccat tttttgagcg atatcaaaag ggatagagtt agcaatacca ccatctagac
    13621 aaagtccttt agaagtatta tgtggctttg agatgaaagg catagatgaa gaagcttcta
    13681 aggcatcaat taaatcttga ccaggttggg gattacgtag cgttacagct tttccgcttt
    13741 ctagagaagt agctacaaca ataaaatcag tttcagactt taaataggct ttattatcga
    13801 aattatgcca atctaatcca tgatcatcaa ataagaaatc taagttaata atactttcat
    13861 gcttaaaagg gcgtgctaag gagatatagt catgatcttt acggtattta acatttacat
    13921 tataagttct ttgatattgt tttgaaacga aattagcgcc atttagagac cctgcagaaa
    13981 ctccaataac acaatcaaat tgaatatcat gttccaaaaa tgtatctaga acgccagaag
    14041 tatagaggcc acgcattgca ccaccttcta aaactagagc tgcattgtaa tacatgtaac
    14101 cattcctttc gaaaaataac tagaattaat ataaacctaa aaagtagaga tagcaagaat
    14161 acaaaggaat aataagagaa tttaaatatt taattagtca aaaacaatgc aactgtaaaa
    14221 tatttaacaa aaaaacaacc tctatcatca aaatagaggc tgttgacaga taaatcttta
    14281 atcaattaag aatacttaag tatatccaag ataagtatta aaataacaac ttaatttaat
    14341 gcttataatc acttattcga cggttttcat atatgataat gcgtcgatac cctttaatgg
    14401 taaataacta gaactaatat ttgattcatc aatattaaga acgtagtctt cttgaatgtt
    14461 tgtaactaag tgagacaaat tgttaatttg ttcagattca aagcggttaa aggataaatt
    14521 acgctttttc ttcatagcat cttctaatgc acgggaaatt gaaatattta agtaatgtcc
    14581 agtttcactg ttagaaatac gccattcaat cttattttcg tcattgttta acttgctaat
    14641 aataatttta ttcatatata attaccacct taataaatgt aaatgctttc cttaacttac
    14701 aagtataact ctactctcat ttacgaataa aagcaagggt aaaattaaaa atataagtaa
    14761 ataattgttt ttgcttattt aaaaagttga atatcaatat aatataagga ttggtatgtt
    14821 aatataattg ttttgatgaa gaattattga atggaatcag ttgttatagc caaattaaaa
    14881 gtatgcaaat ttgttttttt ataaatagca gattgtagat agattattaa agtcaaactt
    14941 aggaaatcaa tttttgataa aataaaaagt tattttaact ttctgaaaaa atatgatttt
    15001 acttatttaa actcaaaaat aatcaaatac tgtcaaataa ggaaaagata ggatttaaca
    15061 gtatatagta aattcaaaaa atagtaatta ataactattg actcagaact taatcagaac
    15121 tcaaaattct aaggatttaa caataaaaca acaattaatt aaataaaaaa atagaaggaa
    15181 tctttcaatt cggtaaagcc tagcaactag ctaggttatt tttttggcaa taaaaaagcc
    15241 ctagacggct ctaggactta cttatttatc aaattttgta gatagcatag ataaatctat
    15301 accagtagaa ttatctgctt tttcattcaa taacgcttca cgttcagctt gtagatcagc
    15361 taatttttga ttcacatcat caagcttttg ttgatgtgca gtatcagcaa ctttctcttc
    15421 attgaagttg gatattactt gtgaggtttt ctctgaatat gcagaggtgc tagcagcttt
    15481 cttaatcaaa gcttctgtaa aatcaccatc accaactaat tcaagagcta gttttattaa
    15541 atttttaatt gatacacttt tgttttcttg tgaaaccatc cattcacggt aaataccatc
    15601 aacagtaata gtataagatt ttgttgaagg atcttttgta ggtcttggca taaaatatca
    15661 cttccaattt ttatttattc atagctttta aaataagttc taaacctttt tcgtttagat
    15721 tttgtgcata ggatttatta atccaaataa caggaacatc aataccacca gaaaaatctt
    15781 tcattttttg agaaagtttt tgtcgtagag cagtttgttc caacatagga attgatccac
    15841 caccgtaaac atacaagatt tccacatttg ctccggcttt tctcattgtt ttacttgctg
    15901 cagtaactat tttatcagca aaaggttcaa gttgttcaaa gacaatttgg cgaactttag
    15961 tctgcattct ttttgctaaa agtgaaactt cctgtgctaa gtaatcttgt agttgggagc
    16021 gtgcttcaaa gttcatgttt tctgtttgta gcacatcaat tgcatcttgc aaagcattac
    16081 cataaccagt aggtagagaa gtagaggcaa ctgcattagc atgaccctct ttaataacaa
    16141 ctaaatcagt agttccttcg ccgatatcaa ttcctagtag attatcaatt ttaactaaat
    16201 cactaacttt aatatcatta gcaagttcag gataattttt tgaaaaatct tgtttaatta
    16261 atccttgtag tttaatatca ctatttttca aatataattg ggcaacttca ccctctaaag
    16321 caacatatac gttcttaaaa ctcaaagaaa cagtaatagg atccttgaag ttatgaaata
    16381 caacagtatg tttactgcca atatacttat taacgtaatt attgataatt ccgttctttt
    16441 taccttcaga aactggtaga gctgttgtca tatttatttc tgtactaagt tgatcggata
    16501 agtcttcacc atttttaact gccaaagaaa tacgttgtgc agctatcatg cttaaagtta
    16561 agatgatagc tagatcatta tcagatttac cagtaaagtc atttacatcg aaagctttta
    16621 aaggtaacga acttttaata gctgcattac cgactaaaaa acgaccctga gtctttactg
    16681 ctgaactgga tatggttaca tccatatgat taatcatacc ttctaagtaa gttaattttt
    16741 cttgatttga attgaattca acgggtttat ttaaatcttg ttcacgttga atagcaatta
    16801 ctgaaggaaa gtgaatatta gtatcttcaa ctttagcctt gacacttcca tagcctaaat
    16861 cattagcaac attcaatttt aaaatattat tttttgacat agaaaatacc ccatttctac
    16921 atcaacatca atccaccttt aattatacat gtaattaagt ataaatcaac tattaatatt
    16981 ataaaaactt ttaaaatgtt tttaatgctt attaaacctt gtattggtta tttttaatta
    17041 cattcaaaaa aataaaaaac aatagtaaat tatttaaaat gttataaaag gtatataaga
    17101 gtataaattc atatagtttg aaatggtaaa aaaatacaaa gtaaattaag aaagtaaaaa
    17161 taccgaaaat cagtttttga ttctcggtat tttgtaataa tattaaggtt atgataatga
    17221 ttattgtaaa gtgtcgctat aaaaatatca agtagaaata gcaaatatga tacaataaag
    17281 attaaataga gaacatagaa ataaggatgg gtttcatgta caatacaata caatacaata
    17341 caatacaata caatacaata caatacaata caatacaata caatacaat
//
