## Fri Jun 28 19:25:45 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_009881235.1/GCA_009881235.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_009881235.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_009881235.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
PKFBPKFJ_00002	1121115.AXVN01000106_gene673	0.0	871.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,3XZR1@572511|Blautia	186801|Clostridia	L	COG COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
PKFBPKFJ_00006	411462.DORLON_00871	2.51e-173	482.0	COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,25B5A@186801|Clostridia,27WHD@189330|Dorea	186801|Clostridia	L	COG COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,rve,rve_2
PKFBPKFJ_00007	411462.DORLON_00869	3.84e-162	454.0	COG2963@1|root,COG2963@2|Bacteria,1V4FD@1239|Firmicutes,24GUY@186801|Clostridia,27W1X@189330|Dorea	186801|Clostridia	L	COG COG2963 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
PKFBPKFJ_00008	457412.RSAG_03502	1.68e-293	803.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,3WIJ3@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
PKFBPKFJ_00009	457412.RSAG_03502	0.0	905.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,3WIJ3@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
PKFBPKFJ_00010	1121115.AXVN01000193_gene1816	6.27e-290	791.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,24AH4@186801|Clostridia,3Y2B2@572511|Blautia	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
PKFBPKFJ_00011	391612.CY0110_01000	1.75e-33	123.0	2DHB2@1|root,2ZZ23@2|Bacteria,1GM7V@1117|Cyanobacteria,3KJRA@43988|Cyanothece	1117|Cyanobacteria	S	Firmicute plasmid replication protein (RepL)	-	-	-	-	-	-	-	-	-	-	-	-	RepL
PKFBPKFJ_00012	457412.RSAG_04537	3.73e-36	132.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
PKFBPKFJ_00013	1121115.AXVN01000122_gene2859	1.54e-154	435.0	2DMJ6@1|root,32RY3@2|Bacteria,1VBBI@1239|Firmicutes,24SVX@186801|Clostridia,3Y00H@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
PKFBPKFJ_00014	1121115.AXVN01000122_gene2858	6.56e-280	768.0	2C3W5@1|root,2ZBIU@2|Bacteria,1UZRE@1239|Firmicutes,24BHB@186801|Clostridia,3XYH0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00015	1121115.AXVN01000122_gene2857	1.09e-282	778.0	COG1388@1|root,COG1388@2|Bacteria,1V4FJ@1239|Firmicutes,24IPI@186801|Clostridia,3XZF7@572511|Blautia	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
PKFBPKFJ_00016	1121115.AXVN01000122_gene2856	4.45e-128	364.0	2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,24JCA@186801|Clostridia,3Y027@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1256)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1256
PKFBPKFJ_00017	1121115.AXVN01000122_gene2855	1.38e-222	613.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3XZRN@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
PKFBPKFJ_00018	1121115.AXVN01000122_gene2854	9.51e-202	558.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
PKFBPKFJ_00019	1121115.AXVN01000122_gene2853	1.24e-148	419.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,3XYWX@572511|Blautia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
PKFBPKFJ_00020	457412.RSAG_02634	1.1e-258	709.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia,3WIXJ@541000|Ruminococcaceae	186801|Clostridia	K	Periplasmic binding protein domain	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
PKFBPKFJ_00021	1121115.AXVN01000122_gene2851	2.17e-140	396.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3XZEE@572511|Blautia	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
PKFBPKFJ_00022	1121115.AXVN01000122_gene2850	3.98e-72	217.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3Y02F@572511|Blautia	186801|Clostridia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
PKFBPKFJ_00023	457412.RSAG_02637	0.0	1045.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3WGA1@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
PKFBPKFJ_00024	1121115.AXVN01000023_gene1809	1.1e-258	709.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,3XZ13@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
PKFBPKFJ_00025	457412.RSAG_02639	0.0	895.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_00026	1121115.AXVN01000023_gene1807	1.5e-111	321.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,3XZVE@572511|Blautia	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
PKFBPKFJ_00028	1121115.AXVN01000023_gene1806	4.81e-252	691.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia,3XZVW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00029	1121115.AXVN01000023_gene1805	1.2e-171	478.0	COG1180@1|root,COG1180@2|Bacteria,1V1GP@1239|Firmicutes,24G76@186801|Clostridia,3XZK7@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
PKFBPKFJ_00030	1121115.AXVN01000023_gene1804	9.89e-199	564.0	COG3584@1|root,COG3883@1|root,COG3584@2|Bacteria,COG3883@2|Bacteria,1UI15@1239|Firmicutes,25EA3@186801|Clostridia,3XZ75@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	-
PKFBPKFJ_00031	1121115.AXVN01000023_gene1803	5.64e-59	182.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,3Y05I@572511|Blautia	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
PKFBPKFJ_00032	1121115.AXVN01000023_gene1802	9.02e-256	702.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3XZRM@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
PKFBPKFJ_00033	1121115.AXVN01000023_gene1801	5.33e-304	829.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3XZGS@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
PKFBPKFJ_00034	457412.RSAG_02647	0.0	924.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,3WGQ1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PKFBPKFJ_00035	457412.RSAG_02648	1.03e-281	770.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,3WJJV@541000|Ruminococcaceae	186801|Clostridia	L	DnaD domain protein	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
PKFBPKFJ_00036	457412.RSAG_02649	5.45e-232	639.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,3WJBS@541000|Ruminococcaceae	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
PKFBPKFJ_00037	457412.RSAG_02650	2.46e-292	797.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ribose-phosphate pyrophosphokinase family	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
PKFBPKFJ_00038	457412.RSAG_02651	1.39e-297	815.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,24E0A@186801|Clostridia,3WKD3@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
PKFBPKFJ_00039	1121115.AXVN01000023_gene1795	1.51e-261	715.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,3XZ47@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
PKFBPKFJ_00040	1121115.AXVN01000023_gene1794	0.0	940.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,3XZAQ@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
PKFBPKFJ_00041	457412.RSAG_02654	0.0	1514.0	COG2247@1|root,COG2755@1|root,COG2247@2|Bacteria,COG2755@2|Bacteria,1UKIA@1239|Firmicutes,25FXT@186801|Clostridia,3WMKI@541000|Ruminococcaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00042	1121115.AXVN01000023_gene1792	0.0	997.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3XZID@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
PKFBPKFJ_00043	457412.RSAG_02656	0.0	1583.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia,3WI6Z@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
PKFBPKFJ_00044	457412.RSAG_02657	1.45e-280	766.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia,3WSRX@541000|Ruminococcaceae	186801|Clostridia	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
PKFBPKFJ_00045	1121115.AXVN01000023_gene1789	4.11e-86	253.0	2E5KN@1|root,330BS@2|Bacteria,1V5P2@1239|Firmicutes,24TCR@186801|Clostridia,3Y0HH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00046	1121115.AXVN01000023_gene1788	7.42e-162	453.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,3XZ1X@572511|Blautia	186801|Clostridia	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
PKFBPKFJ_00047	1121115.AXVN01000023_gene1787	9.1e-54	168.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,3Y0NQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
PKFBPKFJ_00048	1121115.AXVN01000023_gene1786	0.0	1100.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,3XZEM@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
PKFBPKFJ_00049	1121115.AXVN01000023_gene1785	3.34e-91	268.0	2EXFY@1|root,33QS9@2|Bacteria,1VU5K@1239|Firmicutes,24YDE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00050	1121115.AXVN01000023_gene1784	5.23e-256	702.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3XYKG@572511|Blautia	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
PKFBPKFJ_00051	1121115.AXVN01000023_gene1783	1.15e-122	350.0	2DUBI@1|root,33PTJ@2|Bacteria,1VRWC@1239|Firmicutes,24Y88@186801|Clostridia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
PKFBPKFJ_00052	1121115.AXVN01000023_gene1782	1.07e-94	276.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,3Y034@572511|Blautia	186801|Clostridia	FG	Psort location Cytoplasmic, score 8.87	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
PKFBPKFJ_00053	1121115.AXVN01000023_gene1781	1.06e-163	457.0	COG3852@1|root,COG3852@2|Bacteria,1VA7P@1239|Firmicutes,24J8F@186801|Clostridia,3Y29E@572511|Blautia	186801|Clostridia	H	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_00054	457412.RSAG_02667	1.02e-131	374.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,3WJRW@541000|Ruminococcaceae	186801|Clostridia	S	PFAM Rhomboid family	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
PKFBPKFJ_00055	457412.RSAG_02668	0.0	950.0	COG1716@1|root,COG1716@2|Bacteria,1V550@1239|Firmicutes,24BVK@186801|Clostridia,3WRV5@541000|Ruminococcaceae	186801|Clostridia	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
PKFBPKFJ_00056	1121115.AXVN01000023_gene1778	2.15e-104	301.0	2EQ3G@1|root,33HPU@2|Bacteria,1VKDW@1239|Firmicutes,24V35@186801|Clostridia,3Y0MK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
PKFBPKFJ_00057	1121115.AXVN01000023_gene1777	2.03e-94	276.0	COG1989@1|root,COG1989@2|Bacteria,1VMFT@1239|Firmicutes	1239|Firmicutes	NOU	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue	-	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
PKFBPKFJ_00058	1121115.AXVN01000023_gene1776	5.5e-201	556.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia,3Y0C5@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
PKFBPKFJ_00059	1121115.AXVN01000023_gene1775	0.0	929.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24ASZ@186801|Clostridia,3XZFX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00060	1121115.AXVN01000023_gene1774	1.49e-32	113.0	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,3Y0UH@572511|Blautia	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
PKFBPKFJ_00061	457412.RSAG_02674	1.29e-234	647.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia,3WJSN@541000|Ruminococcaceae	186801|Clostridia	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
PKFBPKFJ_00062	457412.RSAG_02675	8.28e-176	491.0	COG4965@1|root,COG4965@2|Bacteria,1V6PB@1239|Firmicutes,24JBR@186801|Clostridia,3WJUZ@541000|Ruminococcaceae	186801|Clostridia	U	Flp pilus assembly protein TadB	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
PKFBPKFJ_00063	1121115.AXVN01000023_gene1771	1.33e-276	757.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,3XZAC@572511|Blautia	186801|Clostridia	U	flp pilus assembly ATPase CpaF	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
PKFBPKFJ_00064	1121115.AXVN01000023_gene1770	2.37e-249	684.0	COG1192@1|root,COG1192@2|Bacteria,1V11K@1239|Firmicutes,24FDX@186801|Clostridia,3XZ68@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
PKFBPKFJ_00065	1121115.AXVN01000023_gene1769	1.22e-126	360.0	COG1989@1|root,COG1989@2|Bacteria	2|Bacteria	NOU	aspartic-type endopeptidase activity	cpaA	-	3.4.23.43	ko:K02278,ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	DiS_P_DiS,Peptidase_A24
PKFBPKFJ_00066	457412.RSAG_02681	9.42e-232	638.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,3WGEJ@541000|Ruminococcaceae	186801|Clostridia	M	Linear amide C-N hydrolase, choloylglycine hydrolase family protein	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
PKFBPKFJ_00067	457412.RSAG_02682	0.0	971.0	COG2865@1|root,COG2865@2|Bacteria,1U8FY@1239|Firmicutes,24B8W@186801|Clostridia,3WJKE@541000|Ruminococcaceae	186801|Clostridia	K	Putative DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
PKFBPKFJ_00068	1121115.AXVN01000124_gene3946	6.42e-87	256.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,3Y0C9@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
PKFBPKFJ_00069	1121115.AXVN01000124_gene3947	0.0	911.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3XYVU@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
PKFBPKFJ_00070	457412.RSAG_02685	1.64e-206	572.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3WHJU@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
PKFBPKFJ_00071	457412.RSAG_02686	0.0	957.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3WGXD@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
PKFBPKFJ_00072	457412.RSAG_02687	1.79e-112	323.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia,3WK3C@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
PKFBPKFJ_00073	457412.RSAG_02688	1.16e-87	260.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,3WKJC@541000|Ruminococcaceae	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
PKFBPKFJ_00074	1121115.AXVN01000124_gene3952	3.21e-32	113.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3Y0KZ@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
PKFBPKFJ_00075	1121115.AXVN01000124_gene3953	1.97e-151	426.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,3XZ99@572511|Blautia	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
PKFBPKFJ_00076	1121115.AXVN01000124_gene3954	3.4e-104	306.0	COG2755@1|root,COG2755@2|Bacteria,1VT0W@1239|Firmicutes,25BMQ@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PKFBPKFJ_00077	1121115.AXVN01000124_gene3955	3.24e-189	525.0	COG0454@1|root,COG0456@2|Bacteria,1V37I@1239|Firmicutes,24IZQ@186801|Clostridia,3XZHS@572511|Blautia	186801|Clostridia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PKFBPKFJ_00078	457412.RSAG_02693	3.09e-120	344.0	COG3275@1|root,COG3275@2|Bacteria,1UJ12@1239|Firmicutes,24Q7D@186801|Clostridia,3WKDP@541000|Ruminococcaceae	186801|Clostridia	T	ECF transporter, substrate-specific component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS,ECF_trnsprt
PKFBPKFJ_00080	1121115.AXVN01000054_gene1898	4.41e-241	667.0	COG3103@1|root,COG3103@2|Bacteria,1UG5Z@1239|Firmicutes,25NDX@186801|Clostridia,3Y048@572511|Blautia	186801|Clostridia	T	Sh3 type 3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00081	1121115.AXVN01000054_gene1897	4.15e-183	512.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia,3XYZC@572511|Blautia	186801|Clostridia	Q	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
PKFBPKFJ_00082	457412.RSAG_02698	4.18e-262	719.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3WHB1@541000|Ruminococcaceae	186801|Clostridia	J	Threonine alanine tRNA ligase second additional domain protein	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
PKFBPKFJ_00083	1121115.AXVN01000054_gene1895	1.12e-115	332.0	COG1595@1|root,COG1595@2|Bacteria,1VB8F@1239|Firmicutes,24PH6@186801|Clostridia,3Y1N5@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_00084	1121115.AXVN01000054_gene1894	2.18e-107	310.0	2BWHH@1|root,33G8D@2|Bacteria,1VM1X@1239|Firmicutes,24W5T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00085	1121115.AXVN01000054_gene1893	4.86e-168	471.0	2E77V@1|root,32VJN@2|Bacteria,1VA37@1239|Firmicutes,24P5M@186801|Clostridia,3Y1P9@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00086	457412.RSAG_02702	1.85e-216	599.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
PKFBPKFJ_00087	1121115.AXVN01000054_gene1891	3.41e-28	103.0	2C1K5@1|root,3415T@2|Bacteria,1VY97@1239|Firmicutes,2522U@186801|Clostridia,3Y25V@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00088	457412.RSAG_02705	2.25e-130	374.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia,3WI9G@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
PKFBPKFJ_00089	457412.RSAG_02706	8.52e-69	209.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia,3WK33@541000|Ruminococcaceae	186801|Clostridia	S	LrgA family	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
PKFBPKFJ_00090	457412.RSAG_02707	1.28e-97	285.0	2BZUE@1|root,31TAF@2|Bacteria,1URY6@1239|Firmicutes,24XVK@186801|Clostridia,3WQSR@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00091	537007.BLAHAN_05958	1.03e-151	434.0	COG1482@1|root,COG1482@2|Bacteria,1V0PH@1239|Firmicutes	1239|Firmicutes	G	mannose-6-phosphate isomerase, class I	manA	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	MannoseP_isomer,NTP_transferase,PMI_typeI
PKFBPKFJ_00092	33035.JPJF01000037_gene2941	2.07e-162	482.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3Y0Z7@572511|Blautia	186801|Clostridia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
PKFBPKFJ_00093	1235799.C818_00832	8.08e-190	537.0	COG2942@1|root,COG2942@2|Bacteria,1TQMG@1239|Firmicutes,24C1F@186801|Clostridia,27JKD@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	-	-	5.1.3.11	ko:K16213	-	-	R01445,R10810	RC00289	ko00000,ko01000	-	-	-	GlcNAc_2-epim
PKFBPKFJ_00094	33035.JPJF01000037_gene2932	5.44e-147	424.0	COG1609@1|root,COG1609@2|Bacteria,1TT55@1239|Firmicutes,24A7X@186801|Clostridia,3Y1M1@572511|Blautia	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
PKFBPKFJ_00095	33035.JPJF01000037_gene2931	0.0	1165.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,3XYN9@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
PKFBPKFJ_00096	1235799.C818_01480	8.17e-23	92.8	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,27S38@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
PKFBPKFJ_00097	1235799.C818_01480	1.16e-52	171.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,27S38@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 1	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
PKFBPKFJ_00098	1235792.C808_05212	6.51e-62	202.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
PKFBPKFJ_00099	592026.GCWU0000282_002318	2.88e-121	348.0	COG3335@1|root,COG3335@2|Bacteria,1UZI4@1239|Firmicutes,24BY8@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
PKFBPKFJ_00101	910314.HMPREF9220_0954	1.15e-30	119.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,4H407@909932|Negativicutes	909932|Negativicutes	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
PKFBPKFJ_00102	1232453.BAIF02000051_gene1044	4.75e-66	209.0	COG0794@1|root,COG0794@2|Bacteria,1TQ04@1239|Firmicutes,249KC@186801|Clostridia	186801|Clostridia	M	sugar phosphate isomerase involved in capsule formation	-	-	5.3.1.13	ko:K06041	ko00540,ko01100,map00540,map01100	M00063	R01530	RC00541	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CBS,SIS
PKFBPKFJ_00103	742740.HMPREF9474_02651	4.34e-114	333.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,21YBV@1506553|Lachnoclostridium	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
PKFBPKFJ_00104	1304880.JAGB01000003_gene1259	3.87e-249	701.0	COG1069@1|root,COG1069@2|Bacteria,1TP8T@1239|Firmicutes,248QY@186801|Clostridia	186801|Clostridia	C	Belongs to the ribulokinase family	araB	-	2.7.1.16	ko:K00853	ko00040,ko01100,map00040,map01100	-	R01526,R02439	RC00002,RC00538	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
PKFBPKFJ_00105	742740.HMPREF9474_02649	9.13e-140	405.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,24BZ9@186801|Clostridia,223YE@1506553|Lachnoclostridium	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PKFBPKFJ_00106	742740.HMPREF9474_02648	5e-207	587.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,21XJ5@1506553|Lachnoclostridium	186801|Clostridia	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
PKFBPKFJ_00107	1121115.AXVN01000151_gene3972	1.11e-41	136.0	COG2909@1|root,COG2909@2|Bacteria,1VGAF@1239|Firmicutes,24SMP@186801|Clostridia,3Y0SH@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PKFBPKFJ_00108	1121115.AXVN01000151_gene3973	4.66e-164	459.0	COG0745@1|root,COG0745@2|Bacteria,1TSCM@1239|Firmicutes,248K7@186801|Clostridia,3Y1AC@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_00109	1121115.AXVN01000202_gene841	4.18e-60	185.0	COG2963@1|root,COG2963@2|Bacteria,1VCC9@1239|Firmicutes,24NYR@186801|Clostridia,3Y1WG@572511|Blautia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
PKFBPKFJ_00110	1121115.AXVN01000202_gene840	1.82e-229	630.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,24DGQ@186801|Clostridia,3Y2AQ@572511|Blautia	186801|Clostridia	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
PKFBPKFJ_00111	1577887.JSYG01000027_gene2263	1.07e-32	121.0	294P0@1|root,2ZS2B@2|Bacteria,1PBQ1@1224|Proteobacteria,1SUI6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	MbeB-like, N-term conserved region	-	-	-	-	-	-	-	-	-	-	-	-	MbeB_N
PKFBPKFJ_00113	1121115.AXVN01000144_gene2939	3.14e-45	149.0	2CFNE@1|root,2ZAY0@2|Bacteria,1UYUK@1239|Firmicutes,24FJT@186801|Clostridia,3Y04G@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00114	1121115.AXVN01000144_gene2940	7.84e-16	71.2	COG4859@1|root,COG4859@2|Bacteria,1UJXZ@1239|Firmicutes,25FE2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2185,DUF4241
PKFBPKFJ_00115	1121115.AXVN01000144_gene2941	1.17e-46	149.0	28N18@1|root,2ZB7G@2|Bacteria,1TRZ3@1239|Firmicutes,24MTK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00116	457412.RSAG_00567	2.68e-84	248.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia,3WJVE@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
PKFBPKFJ_00117	1121115.AXVN01000112_gene2358	0.0	960.0	COG4403@1|root,COG4403@2|Bacteria,1TS6F@1239|Firmicutes,247JU@186801|Clostridia,3XZVN@572511|Blautia	186801|Clostridia	V	Lanthionine synthetase C-like protein	lanM	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
PKFBPKFJ_00118	1280698.AUJS01000071_gene204	7.39e-151	447.0	COG2274@1|root,COG2274@2|Bacteria,1V77J@1239|Firmicutes,25E7C@186801|Clostridia	186801|Clostridia	V	ABC transporter, transmembrane region	-	-	-	ko:K18889	ko02010,map02010	M00707	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.106.13,3.A.1.106.5	-	-	ABC_membrane,ABC_tran,Peptidase_C39
PKFBPKFJ_00119	1121115.AXVN01000112_gene2356	3.15e-153	431.0	2E69V@1|root,330XS@2|Bacteria,1VEQ2@1239|Firmicutes,24T5H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00120	97139.C824_00397	3.2e-226	643.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,251Y5@186801|Clostridia,36UP2@31979|Clostridiaceae	186801|Clostridia	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
PKFBPKFJ_00121	622312.ROSEINA2194_03095	3.01e-58	182.0	COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,24K4W@186801|Clostridia	186801|Clostridia	L	PFAM IS66 Orf2	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
PKFBPKFJ_00122	585394.RHOM_02065	8.54e-27	103.0	28IAH@1|root,2Z8D3@2|Bacteria,1TRGI@1239|Firmicutes,24U6D@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00123	411470.RUMGNA_01463	1.46e-211	585.0	COG0539@1|root,COG0539@2|Bacteria,1UY0Q@1239|Firmicutes,24B4G@186801|Clostridia,3XZMD@572511|Blautia	186801|Clostridia	J	Ribosomal protein S1	-	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
PKFBPKFJ_00124	411470.RUMGNA_01464	0.0	1326.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,3XZAF@572511|Blautia	186801|Clostridia	U	TraM recognition site of TraD and TraG	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
PKFBPKFJ_00125	537007.BLAHAN_06961	2.97e-268	734.0	28IDZ@1|root,2Z8G4@2|Bacteria,1V015@1239|Firmicutes,249QY@186801|Clostridia,3XZGA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00126	1121115.AXVN01000039_gene3278	1.8e-156	439.0	28IFT@1|root,2Z8HE@2|Bacteria,1UY5E@1239|Firmicutes,24E3A@186801|Clostridia,3XZNM@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00127	1121115.AXVN01000039_gene3279	2.81e-118	338.0	28KVJ@1|root,2ZAC5@2|Bacteria,1TRAG@1239|Firmicutes,24DQ9@186801|Clostridia,3XZ34@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00130	1345695.CLSA_c03070	1.1e-84	272.0	COG1032@1|root,COG1032@2|Bacteria,1V8ME@1239|Firmicutes,25CH1@186801|Clostridia,36K5P@31979|Clostridiaceae	186801|Clostridia	C	PFAM Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
PKFBPKFJ_00132	1234679.BN424_2283	2.03e-40	155.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,4HAY2@91061|Bacilli	91061|Bacilli	C	Fe-S oxidoreductases	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
PKFBPKFJ_00133	563040.Saut_0837	2.45e-22	105.0	COG0535@1|root,COG0535@2|Bacteria,1MUQP@1224|Proteobacteria,42N9E@68525|delta/epsilon subdivisions,2YMFD@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	C	Heme d1 biosynthesis protein NirJ	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
PKFBPKFJ_00134	351627.Csac_0565	1.44e-73	245.0	COG1032@1|root,COG1032@2|Bacteria,1V8ME@1239|Firmicutes,25CH1@186801|Clostridia	186801|Clostridia	C	Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
PKFBPKFJ_00135	1121115.AXVN01000039_gene3282	1.99e-198	550.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3Y1EY@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_00136	500632.CLONEX_00642	2.07e-72	226.0	COG1835@1|root,COG1835@2|Bacteria,1UG9X@1239|Firmicutes,24DXD@186801|Clostridia	186801|Clostridia	I	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
PKFBPKFJ_00139	411470.RUMGNA_01475	2.55e-80	249.0	29VC5@1|root,30GSK@2|Bacteria,1UGIZ@1239|Firmicutes,25P18@186801|Clostridia,3Y05V@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00140	658088.HMPREF0987_00262	2.69e-59	184.0	2BCGS@1|root,3262J@2|Bacteria,1US1R@1239|Firmicutes,25A02@186801|Clostridia,27PFM@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
PKFBPKFJ_00141	1121115.AXVN01000039_gene3285	2.58e-87	257.0	COG3708@1|root,COG3708@2|Bacteria,1TTJ9@1239|Firmicutes,2590H@186801|Clostridia,3Y27C@572511|Blautia	186801|Clostridia	K	Protein of unknown function (DUF3788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3788
PKFBPKFJ_00143	1121115.AXVN01000039_gene3286	1.91e-121	346.0	COG4283@1|root,COG4283@2|Bacteria,1TSF1@1239|Firmicutes,2493R@186801|Clostridia,3Y0ND@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1706)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1706
PKFBPKFJ_00144	457412.RSAG_03220	4.36e-15	73.2	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WHQU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	ko:K03733,ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
PKFBPKFJ_00145	1121115.AXVN01000039_gene3287	2.93e-125	356.0	28J10@1|root,2Z8Y3@2|Bacteria,1UYTH@1239|Firmicutes,24FAW@186801|Clostridia,3XZRK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00146	742765.HMPREF9457_02430	1.5e-298	813.0	2CIG8@1|root,2Z7UI@2|Bacteria,1TRB9@1239|Firmicutes,24CHU@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00147	1121115.AXVN01000039_gene3289	4.12e-139	392.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia,3Y0B0@572511|Blautia	186801|Clostridia	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
PKFBPKFJ_00148	1121115.AXVN01000039_gene3290	2.33e-47	151.0	2E7JQ@1|root,3321V@2|Bacteria,1VH9B@1239|Firmicutes,24S3M@186801|Clostridia,3Y0WH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00149	1121115.AXVN01000039_gene3291	4.31e-172	481.0	COG3279@1|root,COG3279@2|Bacteria,1V3QY@1239|Firmicutes,24IT9@186801|Clostridia,3Y1IK@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_00150	457412.RSAG_03226	1.21e-284	778.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,3WINY@541000|Ruminococcaceae	186801|Clostridia	S	SGNH hydrolase-like domain, acetyltransferase AlgX	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
PKFBPKFJ_00151	457412.RSAG_03227	0.0	909.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH3T@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
PKFBPKFJ_00152	457412.RSAG_03228	1.41e-120	344.0	2DNPY@1|root,32YIB@2|Bacteria,1VHHM@1239|Firmicutes,24NJ3@186801|Clostridia,3WMNS@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4358)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4358
PKFBPKFJ_00153	457412.RSAG_03229	1.75e-185	516.0	COG2755@1|root,COG2755@2|Bacteria,1VAV9@1239|Firmicutes	1239|Firmicutes	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PKFBPKFJ_00154	457412.RSAG_03230	1.54e-190	530.0	COG3247@1|root,COG3247@2|Bacteria,1VAQW@1239|Firmicutes,24QIF@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
PKFBPKFJ_00155	1121115.AXVN01000039_gene3297	4.93e-208	574.0	COG0010@1|root,COG0010@2|Bacteria,1V6Y2@1239|Firmicutes,24K01@186801|Clostridia,3Y08B@572511|Blautia	186801|Clostridia	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
PKFBPKFJ_00156	457412.RSAG_03232	1.3e-194	538.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24BK7@186801|Clostridia,3WSCN@541000|Ruminococcaceae	186801|Clostridia	M	Prolipoprotein diacylglyceryl transferase	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
PKFBPKFJ_00157	457412.RSAG_03233	0.0	1153.0	COG1404@1|root,COG1404@2|Bacteria,1TQE0@1239|Firmicutes,25B1A@186801|Clostridia,3WI3C@541000|Ruminococcaceae	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
PKFBPKFJ_00158	1121115.AXVN01000039_gene3300	9.57e-304	832.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	xanP	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
PKFBPKFJ_00159	457412.RSAG_03235	5.09e-304	828.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3WHGE@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
PKFBPKFJ_00160	457412.RSAG_03236	0.0	1110.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGRP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PKFBPKFJ_00161	1121115.AXVN01000039_gene3303	7.16e-64	196.0	2F5U3@1|root,33YD0@2|Bacteria,1VVXV@1239|Firmicutes,250VV@186801|Clostridia,3Y21G@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00162	1121115.AXVN01000039_gene3304	1.36e-309	842.0	COG3864@1|root,COG3864@2|Bacteria,1VS2U@1239|Firmicutes,24ZZ3@186801|Clostridia,3XZT4@572511|Blautia	186801|Clostridia	S	Putative metallopeptidase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
PKFBPKFJ_00163	1121115.AXVN01000058_gene2534	0.0	1001.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3XZHN@572511|Blautia	186801|Clostridia	S	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
PKFBPKFJ_00164	1121115.AXVN01000058_gene2535	7.12e-199	550.0	COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,24GN2@186801|Clostridia,3XZ9S@572511|Blautia	186801|Clostridia	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
PKFBPKFJ_00165	1121115.AXVN01000058_gene2536	4.68e-178	495.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,3XZIR@572511|Blautia	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
PKFBPKFJ_00166	1121115.AXVN01000058_gene2537	1.4e-40	133.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,3Y0KE@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
PKFBPKFJ_00167	1121115.AXVN01000058_gene2538	1.39e-62	192.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3Y068@572511|Blautia	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
PKFBPKFJ_00168	457412.RSAG_03244	1.37e-86	256.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,3WJ32@541000|Ruminococcaceae	186801|Clostridia	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
PKFBPKFJ_00169	1121115.AXVN01000058_gene2540	3.05e-57	177.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,3Y0A3@572511|Blautia	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
PKFBPKFJ_00170	1121115.AXVN01000058_gene2541	0.0	1303.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,3XYI8@572511|Blautia	186801|Clostridia	T	signaling protein consisting of a modified GGDEF domain and a DHH domain	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
PKFBPKFJ_00171	1121115.AXVN01000058_gene2542	2.09e-95	278.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3XZYF@572511|Blautia	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
PKFBPKFJ_00172	1121115.AXVN01000058_gene2543	2.12e-310	847.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3XYP7@572511|Blautia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
PKFBPKFJ_00173	457412.RSAG_03250	1.01e-99	290.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24VXI@186801|Clostridia,3WRY4@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
PKFBPKFJ_00174	1121115.AXVN01000058_gene2545	3.78e-20	81.6	COG1148@1|root,COG1148@2|Bacteria,1UI0M@1239|Firmicutes,25E99@186801|Clostridia,3Y0Q0@572511|Blautia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
PKFBPKFJ_00175	457412.RSAG_03253	2.44e-286	781.0	COG1744@1|root,COG1744@2|Bacteria,1UZEP@1239|Firmicutes,25C7C@186801|Clostridia,3WSBG@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
PKFBPKFJ_00176	457412.RSAG_03254	0.0	981.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3WSIS@541000|Ruminococcaceae	186801|Clostridia	S	transport systems ATPase components	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
PKFBPKFJ_00177	457412.RSAG_03255	2.21e-254	698.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3WHQZ@541000|Ruminococcaceae	186801|Clostridia	S	transport system permease	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
PKFBPKFJ_00178	457412.RSAG_03256	1.17e-221	612.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,3WIJ5@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
PKFBPKFJ_00179	1121115.AXVN01000058_gene2550	1.42e-39	131.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia,3Y0MQ@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
PKFBPKFJ_00180	457412.RSAG_03258	1.81e-170	476.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia	186801|Clostridia	NOT	Negative regulator of genetic competence	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
PKFBPKFJ_00181	1121115.AXVN01000058_gene2552	1.17e-38	129.0	2EHIK@1|root,3498W@2|Bacteria,1VYKX@1239|Firmicutes,252YA@186801|Clostridia,3Y0QM@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00182	457412.RSAG_03260	0.0	1048.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia,3WIAH@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl hydrolase	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
PKFBPKFJ_00183	457412.RSAG_03261	1.79e-148	419.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,3WIGM@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
PKFBPKFJ_00184	1121115.AXVN01000058_gene2555	0.0	1282.0	COG5427@1|root,COG5427@2|Bacteria,1UXXM@1239|Firmicutes,24EF9@186801|Clostridia,3XZFE@572511|Blautia	186801|Clostridia	M	chaperone-mediated protein folding	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00185	1121115.AXVN01000058_gene2556	0.0	1467.0	COG5427@1|root,COG5427@2|Bacteria,1UY7V@1239|Firmicutes,24BA0@186801|Clostridia,3XZJV@572511|Blautia	186801|Clostridia	S	Uncharacterized membrane protein (DUF2298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2298
PKFBPKFJ_00186	457412.RSAG_03265	2.24e-262	719.0	COG2755@1|root,COG2755@2|Bacteria	2|Bacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PKFBPKFJ_00187	1121115.AXVN01000135_gene973	1.79e-244	672.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3XZ73@572511|Blautia	186801|Clostridia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
PKFBPKFJ_00188	1121115.AXVN01000135_gene972	9.72e-103	296.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3XZXS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
PKFBPKFJ_00189	457412.RSAG_03268	3.12e-120	342.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,3WRVA@541000|Ruminococcaceae	186801|Clostridia	F	MafB19-like deaminase	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
PKFBPKFJ_00190	1121115.AXVN01000135_gene969	0.0	986.0	COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,25E98@186801|Clostridia,3XZ9B@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
PKFBPKFJ_00191	457412.RSAG_03270	0.0	866.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3WGBR@541000|Ruminococcaceae	186801|Clostridia	J	tRNA nucleotidyltransferase poly(A) polymerase	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
PKFBPKFJ_00192	457412.RSAG_03271	1.12e-246	677.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia,3WJKX@541000|Ruminococcaceae	186801|Clostridia	S	Spore coat protein, CotS family	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
PKFBPKFJ_00193	1121115.AXVN01000099_gene778	1.6e-55	174.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3Y0HQ@572511|Blautia	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
PKFBPKFJ_00194	1121115.AXVN01000099_gene779	3.38e-46	149.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,3Y0D7@572511|Blautia	186801|Clostridia	J	COG COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
PKFBPKFJ_00195	457412.RSAG_03274	8.11e-58	179.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,3WKKJ@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation protein YabP	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
PKFBPKFJ_00196	457412.RSAG_03275	9.77e-101	292.0	2EFTM@1|root,3095D@2|Bacteria,1U4G7@1239|Firmicutes,25JHX@186801|Clostridia,3WR8N@541000|Ruminococcaceae	186801|Clostridia	S	Spore cortex protein YabQ (Spore_YabQ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
PKFBPKFJ_00197	457412.RSAG_03276	2.36e-47	153.0	COG2919@1|root,COG2919@2|Bacteria,1VX29@1239|Firmicutes,252JU@186801|Clostridia,3WMKM@541000|Ruminococcaceae	186801|Clostridia	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
PKFBPKFJ_00198	457412.RSAG_03277	0.0	981.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,3WH68@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
PKFBPKFJ_00199	457412.RSAG_03278	0.0	966.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,3WHDC@541000|Ruminococcaceae	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
PKFBPKFJ_00200	457412.RSAG_04578	3.04e-122	348.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,3WIX7@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the purine pyrimidine phosphoribosyltransferase family	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
PKFBPKFJ_00201	1121115.AXVN01000099_gene785	0.0	1147.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XYI4@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
PKFBPKFJ_00202	1121115.AXVN01000099_gene786	0.0	1473.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,3XYPB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	tvaI	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
PKFBPKFJ_00204	1121115.AXVN01000099_gene787	1.41e-207	573.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZ5J@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
PKFBPKFJ_00205	457412.RSAG_03282	0.0	920.0	COG1376@1|root,COG1376@2|Bacteria,1W706@1239|Firmicutes,258MI@186801|Clostridia,3WN4E@541000|Ruminococcaceae	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
PKFBPKFJ_00206	457412.RSAG_03283	4.67e-127	361.0	COG0778@1|root,COG0778@2|Bacteria,1V80D@1239|Firmicutes,24I9R@186801|Clostridia,3WRRJ@541000|Ruminococcaceae	186801|Clostridia	C	Nitroreductase family	noxC	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
PKFBPKFJ_00207	1577887.JSYG01000040_gene3168	1.03e-50	164.0	2CEP3@1|root,32XK3@2|Bacteria,1MZV8@1224|Proteobacteria	1224|Proteobacteria	S	Conjugal transfer protein TraD	-	-	-	-	-	-	-	-	-	-	-	-	TraD
PKFBPKFJ_00208	457412.RSAG_01800	0.0	1098.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,3WGW2@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_00209	1121115.AXVN01000119_gene3269	2.28e-121	347.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,3Y01B@572511|Blautia	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
PKFBPKFJ_00210	1121115.AXVN01000119_gene3268	0.0	899.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia,3XZRQ@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
PKFBPKFJ_00211	457412.RSAG_01796	5.97e-145	408.0	COG1247@1|root,COG1247@2|Bacteria,1UKI4@1239|Firmicutes,25FXM@186801|Clostridia	186801|Clostridia	M	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PKFBPKFJ_00212	1121115.AXVN01000136_gene975	1.42e-289	790.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,3XZRE@572511|Blautia	186801|Clostridia	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
PKFBPKFJ_00213	457412.RSAG_01794	1.12e-125	357.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,3WJDN@541000|Ruminococcaceae	186801|Clostridia	S	Conserved protein domain typically associated with flavoprotein oxygenases DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
PKFBPKFJ_00214	1121115.AXVN01000136_gene977	1.2e-95	278.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia,3Y0F5@572511|Blautia	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00215	1121115.AXVN01000136_gene978	5.33e-209	577.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia,3XZ5E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00216	1121115.AXVN01000136_gene979	2.91e-146	412.0	COG0484@1|root,COG0484@2|Bacteria,1UWW2@1239|Firmicutes,25CGC@186801|Clostridia,3XZTD@572511|Blautia	186801|Clostridia	O	DnaJ molecular chaperone homology domain	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
PKFBPKFJ_00217	1121115.AXVN01000136_gene980	2.33e-238	655.0	COG1712@1|root,COG1712@2|Bacteria,1TQ4R@1239|Firmicutes,2499V@186801|Clostridia,3XYQU@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate	ddh	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C,DapB_N
PKFBPKFJ_00218	1121115.AXVN01000136_gene981	4.85e-255	711.0	COG5263@1|root,COG5263@2|Bacteria,1UK2Z@1239|Firmicutes,24XW0@186801|Clostridia,3XZWP@572511|Blautia	186801|Clostridia	S	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
PKFBPKFJ_00219	457412.RSAG_01788	6.1e-211	598.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,3WHR8@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
PKFBPKFJ_00220	1121115.AXVN01000126_gene3813	1.73e-81	241.0	COG4810@1|root,COG4810@2|Bacteria,1V452@1239|Firmicutes,25DMT@186801|Clostridia,3Y27X@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
PKFBPKFJ_00221	1121115.AXVN01000126_gene3814	9.74e-98	284.0	COG4810@1|root,COG4810@2|Bacteria,1V5A1@1239|Firmicutes,24IPC@186801|Clostridia,3Y03M@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
PKFBPKFJ_00222	457412.RSAG_01785	3.45e-121	345.0	COG4917@1|root,COG4917@2|Bacteria,1V54Y@1239|Firmicutes,25DMI@186801|Clostridia	186801|Clostridia	E	Ethanolamine utilisation - propanediol utilisation	-	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
PKFBPKFJ_00223	1121115.AXVN01000126_gene3816	5.48e-74	220.0	COG2158@1|root,COG2158@2|Bacteria,1VFNA@1239|Firmicutes,24MYB@186801|Clostridia,3Y0C2@572511|Blautia	186801|Clostridia	S	Cysteine-rich small domain	-	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
PKFBPKFJ_00224	457412.RSAG_01783	0.0	1494.0	COG4733@1|root,COG4870@1|root,COG4733@2|Bacteria,COG4870@2|Bacteria,1V2GU@1239|Firmicutes,24GPX@186801|Clostridia,3WRJP@541000|Ruminococcaceae	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,Big_2,Flg_new,Peptidase_C1
PKFBPKFJ_00225	1121115.AXVN01000126_gene3818	1.5e-179	506.0	COG3266@1|root,COG3266@2|Bacteria,1VS06@1239|Firmicutes,24YEU@186801|Clostridia,3Y1K6@572511|Blautia	186801|Clostridia	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00226	1121115.AXVN01000086_gene3999	4.49e-89	261.0	2EYFK@1|root,33RPH@2|Bacteria,1VT8U@1239|Firmicutes,24XWV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00227	457412.RSAG_01780	0.0	1697.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3WH79@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate formate lyase	-	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
PKFBPKFJ_00228	457412.RSAG_01779	1.4e-195	541.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,3WIZP@541000|Ruminococcaceae	186801|Clostridia	O	4Fe-4S single cluster domain	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
PKFBPKFJ_00229	1121115.AXVN01000086_gene4002	7.01e-214	590.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3XZRB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
PKFBPKFJ_00230	1121115.AXVN01000086_gene4003	0.0	912.0	COG1012@1|root,COG1012@2|Bacteria,1TRGK@1239|Firmicutes,2480V@186801|Clostridia,3XZI5@572511|Blautia	186801|Clostridia	C	Aldehyde dehydrogenase family	eutE	-	1.2.1.10,1.2.1.87	ko:K00132,ko:K13922	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00228,R01172,R09097	RC00004,RC00184,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh
PKFBPKFJ_00231	1121115.AXVN01000086_gene4004	6.66e-302	822.0	COG1063@1|root,COG1063@2|Bacteria,1TS84@1239|Firmicutes,2484Q@186801|Clostridia,3XYZP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
PKFBPKFJ_00232	1121115.AXVN01000086_gene4005	2.19e-67	204.0	2CTB7@1|root,32ST1@2|Bacteria,1UPS8@1239|Firmicutes,25HN2@186801|Clostridia	186801|Clostridia	S	BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
PKFBPKFJ_00233	1121115.AXVN01000086_gene4006	7.33e-51	161.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y1R4@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
PKFBPKFJ_00234	1121115.AXVN01000086_gene4007	1.77e-62	191.0	COG4577@1|root,COG4577@2|Bacteria,1V9YU@1239|Firmicutes,24MUN@186801|Clostridia,3Y0DW@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
PKFBPKFJ_00235	1121115.AXVN01000086_gene4008	1.22e-69	214.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
PKFBPKFJ_00236	457412.RSAG_01771	2.7e-146	412.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,3WJCD@541000|Ruminococcaceae	186801|Clostridia	Q	Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate	pduL	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTAC
PKFBPKFJ_00237	1121115.AXVN01000086_gene4010	9.07e-52	164.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,3Y0FT@572511|Blautia	186801|Clostridia	CQ	COG COG4576 Carbon dioxide concentrating mechanism carboxysome shell protein	eutN	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
PKFBPKFJ_00238	1121115.AXVN01000086_gene4011	0.0	869.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XZ7S@572511|Blautia	186801|Clostridia	C	Respiratory-chain NADH dehydrogenase 51 Kd subunit	-	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,Fer4_17,RnfC_N,SLBB
PKFBPKFJ_00239	1121115.AXVN01000086_gene4012	6.28e-118	338.0	COG4577@1|root,COG4577@2|Bacteria,1UKDS@1239|Firmicutes,24IS5@186801|Clostridia,3XZUS@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	csoS1C	-	-	-	-	-	-	-	-	-	-	-	BMC
PKFBPKFJ_00240	1121115.AXVN01000086_gene4013	3.65e-173	484.0	COG1349@1|root,COG1349@2|Bacteria,1UZ6T@1239|Firmicutes,24B16@186801|Clostridia,3XZ48@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
PKFBPKFJ_00241	1121115.AXVN01000086_gene4014	6.58e-275	752.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XZNH@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
PKFBPKFJ_00242	1121115.AXVN01000086_gene4015	1.07e-220	612.0	COG2096@1|root,COG3193@1|root,COG2096@2|Bacteria,COG3193@2|Bacteria,1V3PI@1239|Firmicutes,24C7G@186801|Clostridia,3Y0ZK@572511|Blautia	186801|Clostridia	S	Cobalamin adenosyltransferase	-	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans,Haem_degrading
PKFBPKFJ_00243	457412.RSAG_01764	1.26e-212	586.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24BXX@186801|Clostridia,3WKHG@541000|Ruminococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PKFBPKFJ_00244	1121115.AXVN01000081_gene3042	0.0	1232.0	COG2407@1|root,COG2407@2|Bacteria,1TQ5Q@1239|Firmicutes,248V0@186801|Clostridia,3XZ8N@572511|Blautia	186801|Clostridia	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
PKFBPKFJ_00245	457412.RSAG_03510	9.25e-103	297.0	COG4154@1|root,COG4154@2|Bacteria,1V402@1239|Firmicutes,24FU7@186801|Clostridia,3WJ3H@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the RbsD FucU family	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
PKFBPKFJ_00246	457412.RSAG_01762	0.0	1038.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3WJ5A@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
PKFBPKFJ_00247	1121115.AXVN01000081_gene3045	0.0	1146.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3XZ6E@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
PKFBPKFJ_00248	1121115.AXVN01000081_gene3046	1.67e-225	622.0	COG1879@1|root,COG1879@2|Bacteria,1TPWA@1239|Firmicutes,25PX0@186801|Clostridia,3XYI7@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
PKFBPKFJ_00249	457412.RSAG_01759	2.59e-229	632.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3WNJT@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
PKFBPKFJ_00250	1121115.AXVN01000081_gene3048	0.0	973.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3XZ1W@572511|Blautia	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
PKFBPKFJ_00251	1121115.AXVN01000081_gene3049	2.02e-222	614.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3XZJF@572511|Blautia	186801|Clostridia	P	COG COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
PKFBPKFJ_00252	1121115.AXVN01000081_gene3050	3.4e-239	660.0	COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3XZJZ@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
PKFBPKFJ_00253	1121115.AXVN01000081_gene3051	0.0	949.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3XYNN@572511|Blautia	186801|Clostridia	H	FGGY family of carbohydrate kinases, C-terminal domain	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
PKFBPKFJ_00254	1121115.AXVN01000081_gene3052	6.52e-292	796.0	COG0037@1|root,COG0607@1|root,COG0037@2|Bacteria,COG0607@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,3XYS6@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	ttcA	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3,Rhodanese
PKFBPKFJ_00256	1121115.AXVN01000081_gene3053	1.13e-171	480.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,3XZ2M@572511|Blautia	186801|Clostridia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
PKFBPKFJ_00257	1121115.AXVN01000081_gene3054	1.1e-284	782.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,3XZGY@572511|Blautia	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
PKFBPKFJ_00258	457412.RSAG_01750	0.0	1344.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3WI2B@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
PKFBPKFJ_00259	1121115.AXVN01000116_gene2327	0.0	874.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	agcS_2	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
PKFBPKFJ_00260	1121115.AXVN01000116_gene2328	4.58e-235	648.0	COG1865@1|root,COG1865@2|Bacteria,1TQHV@1239|Firmicutes,24AA4@186801|Clostridia,3Y0CC@572511|Blautia	186801|Clostridia	S	Adenosylcobinamide amidohydrolase	cbiZ	-	-	-	-	-	-	-	-	-	-	-	CbiZ
PKFBPKFJ_00261	1121115.AXVN01000116_gene2329	2.26e-30	110.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
PKFBPKFJ_00262	1121115.AXVN01000116_gene2330	2.01e-60	192.0	COG3209@1|root,COG3209@2|Bacteria,1VE5U@1239|Firmicutes,250UW@186801|Clostridia	186801|Clostridia	M	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5,cobW
PKFBPKFJ_00263	1121115.AXVN01000071_gene3944	2.28e-167	468.0	2DG4C@1|root,2ZUFC@2|Bacteria,1W4QP@1239|Firmicutes,257CV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00264	1121115.AXVN01000071_gene3943	0.0	3164.0	COG3064@1|root,COG5492@1|root,COG3064@2|Bacteria,COG5492@2|Bacteria,1TS8J@1239|Firmicutes,24A7I@186801|Clostridia,3Y1MU@572511|Blautia	186801|Clostridia	N	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Flg_new,LRR_5,N_methyl,fn3
PKFBPKFJ_00266	1121115.AXVN01000071_gene3941	0.0	1439.0	COG1657@1|root,COG5492@1|root,COG1657@2|Bacteria,COG5492@2|Bacteria,1UZVS@1239|Firmicutes,24DV2@186801|Clostridia,3Y094@572511|Blautia	186801|Clostridia	IN	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Prenyltrans,SLH,SQHop_cyclase_C
PKFBPKFJ_00267	1121115.AXVN01000071_gene3940	1.05e-274	754.0	COG2247@1|root,COG2247@2|Bacteria,1UNK1@1239|Firmicutes,25H40@186801|Clostridia	186801|Clostridia	M	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
PKFBPKFJ_00268	1121115.AXVN01000071_gene3939	3.05e-235	647.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,3XZVA@572511|Blautia	186801|Clostridia	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
PKFBPKFJ_00269	1121115.AXVN01000071_gene3938	0.0	1137.0	COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,3XYUV@572511|Blautia	186801|Clostridia	G	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS,ECF_trnsprt
PKFBPKFJ_00270	1121115.AXVN01000071_gene3937	3.31e-206	571.0	COG4720@1|root,COG4720@2|Bacteria,1V2DR@1239|Firmicutes,249XR@186801|Clostridia,3XZUX@572511|Blautia	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF-ribofla_trS,ECF_trnsprt
PKFBPKFJ_00271	1121115.AXVN01000071_gene3936	0.0	1327.0	COG5492@1|root,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,3Y0E9@572511|Blautia	186801|Clostridia	N	endoglucanase-related protein, glucosyl hydrolase family 9 protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF11,DUF4430,Flg_new
PKFBPKFJ_00272	888821.HMPREF9394_0998	1.27e-23	94.7	2EAIY@1|root,334MX@2|Bacteria,1VG5C@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00273	1121115.AXVN01000071_gene3935	1.97e-171	479.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia,3XZMC@572511|Blautia	186801|Clostridia	S	Uncharacterised protein family UPF0066	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
PKFBPKFJ_00274	457412.RSAG_01747	2.84e-316	861.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3WHC9@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the aspartokinase family	thrA	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
PKFBPKFJ_00275	457412.RSAG_01746	0.0	1580.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,3WGEC@541000|Ruminococcaceae	186801|Clostridia	L	HELICc2	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
PKFBPKFJ_00276	1121115.AXVN01000118_gene3311	3.01e-315	863.0	COG2367@1|root,COG2367@2|Bacteria,1V6K6@1239|Firmicutes,24KPP@186801|Clostridia,3Y01V@572511|Blautia	186801|Clostridia	V	Beta-lactamase enzyme family	-	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
PKFBPKFJ_00277	1121115.AXVN01000118_gene3310	1.07e-303	828.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25AGX@186801|Clostridia,3XZXG@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH_2
PKFBPKFJ_00278	457412.RSAG_01743	1.05e-112	323.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,3WITA@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
PKFBPKFJ_00279	1121115.AXVN01000118_gene3308	0.0	921.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3XZA4@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
PKFBPKFJ_00280	457412.RSAG_01741	2.48e-106	307.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,3WJN8@541000|Ruminococcaceae	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
PKFBPKFJ_00281	1121115.AXVN01000118_gene3306	1.05e-172	482.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3XZ93@572511|Blautia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
PKFBPKFJ_00282	1121115.AXVN01000118_gene3305	3.32e-135	383.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia,3XZYB@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_00284	457412.RSAG_01639	5.11e-194	542.0	COG0503@1|root,COG0503@2|Bacteria,1UZSF@1239|Firmicutes,24FUM@186801|Clostridia,3WJ42@541000|Ruminococcaceae	186801|Clostridia	F	Phosphoribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PRTase_2,TRSP
PKFBPKFJ_00285	457412.RSAG_01638	1.56e-254	697.0	COG1358@1|root,COG1358@2|Bacteria,1TP5Y@1239|Firmicutes,2487J@186801|Clostridia,3WH6S@541000|Ruminococcaceae	186801|Clostridia	J	PELOTA RNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PELOTA_1,PRTase_1,PRTase_2,TRSP
PKFBPKFJ_00286	1121115.AXVN01000018_gene45	3.16e-232	639.0	COG2301@1|root,COG2301@2|Bacteria,1TSF2@1239|Firmicutes,249TC@186801|Clostridia,3Y1G9@572511|Blautia	186801|Clostridia	G	C-C_Bond_Lyase of the TIM-Barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	C-C_Bond_Lyase
PKFBPKFJ_00287	1121115.AXVN01000018_gene46	0.0	1529.0	2BVVP@1|root,2Z9CR@2|Bacteria,1TRYC@1239|Firmicutes,2487Q@186801|Clostridia,3Y1D8@572511|Blautia	186801|Clostridia	S	Putative component of 'biosynthetic module'	-	-	-	-	-	-	-	-	-	-	-	-	YceG_bac
PKFBPKFJ_00288	1121115.AXVN01000018_gene47	1.02e-258	711.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3Y1EX@572511|Blautia	186801|Clostridia	P	Toxic anion resistance protein (TelA)	-	-	-	-	-	-	-	-	-	-	-	-	TelA
PKFBPKFJ_00289	1121115.AXVN01000018_gene48	1.2e-137	389.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,3Y15Q@572511|Blautia	186801|Clostridia	T	TerD domain	terD_2	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
PKFBPKFJ_00290	1121115.AXVN01000018_gene49	2.72e-137	389.0	COG2310@1|root,COG2310@2|Bacteria,1TNZQ@1239|Firmicutes,24A3Y@186801|Clostridia,3Y1A0@572511|Blautia	186801|Clostridia	T	TerD domain	-	-	-	ko:K05795	-	-	-	-	ko00000	-	-	-	TerD
PKFBPKFJ_00291	1121115.AXVN01000018_gene50	1.78e-145	409.0	COG2310@1|root,COG2310@2|Bacteria,1TR98@1239|Firmicutes,24FZM@186801|Clostridia,3Y13G@572511|Blautia	186801|Clostridia	T	TerD domain	yceC	-	-	-	-	-	-	-	-	-	-	-	TerD
PKFBPKFJ_00292	1121115.AXVN01000018_gene51	0.0	1600.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3XZ0A@572511|Blautia	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
PKFBPKFJ_00293	457412.RSAG_01629	0.0	1182.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia,3WHB4@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
PKFBPKFJ_00294	457412.RSAG_01628	4.67e-147	416.0	COG0791@1|root,COG0791@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,3WRJN@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60,SH3_3
PKFBPKFJ_00295	1121115.AXVN01000018_gene55	3.03e-134	381.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,3XYVE@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
PKFBPKFJ_00296	1121115.AXVN01000018_gene56	0.0	913.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,3XZA3@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
PKFBPKFJ_00297	457412.RSAG_01625	0.0	1171.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,3WGBK@541000|Ruminococcaceae	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
PKFBPKFJ_00298	1121115.AXVN01000018_gene58	1.78e-128	366.0	COG1390@1|root,COG1390@2|Bacteria,1V7UJ@1239|Firmicutes,24ICM@186801|Clostridia,3Y0B1@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
PKFBPKFJ_00299	1121115.AXVN01000018_gene59	5.62e-69	208.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,3Y07R@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
PKFBPKFJ_00300	1121115.AXVN01000018_gene60	1.37e-84	251.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,24RB6@186801|Clostridia,3Y0BA@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
PKFBPKFJ_00301	1121115.AXVN01000018_gene61	0.0	1267.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3XZ9K@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
PKFBPKFJ_00302	457412.RSAG_01620	1.75e-254	697.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,24A4E@186801|Clostridia,3WGJ9@541000|Ruminococcaceae	186801|Clostridia	C	Archaeal vacuolar-type H -ATPase subunit C	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
PKFBPKFJ_00303	1121115.AXVN01000018_gene63	5.1e-43	142.0	2EC7P@1|root,33668@2|Bacteria,1VHK0@1239|Firmicutes,24R0C@186801|Clostridia,3Y0UW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00304	1121115.AXVN01000018_gene64	6.16e-160	447.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,3XZ71@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
PKFBPKFJ_00306	457412.RSAG_01617	0.0	919.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia,3WHXK@541000|Ruminococcaceae	186801|Clostridia	I	Phospholipase D. Active site motifs.	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
PKFBPKFJ_00307	457412.RSAG_01616	0.0	1672.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3WI2B@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Glyco_hydro_31
PKFBPKFJ_00308	457412.RSAG_04692	8.26e-309	841.0	COG3385@1|root,COG3385@2|Bacteria,1UHBB@1239|Firmicutes,24ETX@186801|Clostridia	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PKFBPKFJ_00309	457412.RSAG_01615	0.0	1054.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3WGXK@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
PKFBPKFJ_00310	1121289.JHVL01000079_gene1189	1.49e-10	57.8	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24R3P@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00311	500632.CLONEX_00839	1.14e-187	530.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_00312	397290.C810_00824	7.42e-36	126.0	2AC9W@1|root,311UM@2|Bacteria,1V5SJ@1239|Firmicutes,24IEX@186801|Clostridia,27MBK@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00313	140626.JHWB01000009_gene1329	2.39e-169	480.0	COG1066@1|root,COG1066@2|Bacteria,1UIA9@1239|Firmicutes,25EF9@186801|Clostridia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
PKFBPKFJ_00314	1235793.C809_02145	1.96e-25	100.0	2DINV@1|root,303RW@2|Bacteria,1V6BI@1239|Firmicutes,24HNZ@186801|Clostridia	186801|Clostridia	S	Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PKFBPKFJ_00315	1540257.JQMW01000011_gene2029	1.46e-107	331.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,36KE8@31979|Clostridiaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PKFBPKFJ_00316	1034347.CAHJ01000005_gene2492	1.17e-185	533.0	COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,4HFAI@91061|Bacilli,1ZBQM@1386|Bacillus	91061|Bacilli	L	DNA (cytosine-5-)-methyltransferase activity	ddeI	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
PKFBPKFJ_00317	643867.Ftrac_2142	4.38e-29	122.0	28MJP@1|root,2ZAW3@2|Bacteria,4NKRQ@976|Bacteroidetes,47TSU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00318	545696.HOLDEFILI_03630	2.08e-181	540.0	COG1131@1|root,COG1672@1|root,COG1131@2|Bacteria,COG1672@2|Bacteria,1V0HG@1239|Firmicutes	1239|Firmicutes	V	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_13
PKFBPKFJ_00319	272563.CD630_33260	6.97e-283	773.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24EQM@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_00320	1121115.AXVN01000141_gene2384	2.06e-38	128.0	2ARET@1|root,31GQW@2|Bacteria,1TUXE@1239|Firmicutes,25NXF@186801|Clostridia,3Y0Q5@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3173
PKFBPKFJ_00321	411459.RUMOBE_00905	2.99e-49	156.0	2AJW5@1|root,32RUV@2|Bacteria,1VA55@1239|Firmicutes,24NMK@186801|Clostridia,3Y1TF@572511|Blautia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
PKFBPKFJ_00322	658086.HMPREF0994_05179	8.74e-95	276.0	COG1595@1|root,COG1595@2|Bacteria,1TSMC@1239|Firmicutes,24FTZ@186801|Clostridia,27MU1@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
PKFBPKFJ_00323	1226325.HMPREF1548_01839	1.08e-261	750.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,36DMM@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PKFBPKFJ_00324	411468.CLOSCI_02865	2.6e-141	401.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,21XST@1506553|Lachnoclostridium	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.82	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_00325	411468.CLOSCI_02864	4.78e-186	529.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,21Z5D@1506553|Lachnoclostridium	186801|Clostridia	T	signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_00326	411468.CLOSCI_02863	1.43e-138	394.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,21XX7@1506553|Lachnoclostridium	186801|Clostridia	K	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_00327	1121115.AXVN01000026_gene1030	3.09e-30	107.0	COG3177@1|root,COG3177@2|Bacteria	2|Bacteria	D	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_17
PKFBPKFJ_00328	658086.HMPREF0994_05172	2.12e-73	221.0	COG1396@1|root,COG1396@2|Bacteria,1UJXU@1239|Firmicutes,25FDU@186801|Clostridia,27PN1@186928|unclassified Lachnospiraceae	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_00329	1121115.AXVN01000067_gene3484	4.33e-205	568.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,3Y0Z6@572511|Blautia	186801|Clostridia	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
PKFBPKFJ_00330	658086.HMPREF0994_05170	4.27e-228	629.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,27M4A@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Lysozyme-like	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
PKFBPKFJ_00331	411459.RUMOBE_00894	0.0	1209.0	COG5602@1|root,COG5602@2|Bacteria,1UJ7A@1239|Firmicutes,25EXP@186801|Clostridia,3Y18X@572511|Blautia	186801|Clostridia	B	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00332	1121115.AXVN01000067_gene3481	0.0	1577.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,24AAP@186801|Clostridia,3Y19W@572511|Blautia	186801|Clostridia	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
PKFBPKFJ_00333	272563.CD630_33390	1.14e-88	260.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,24FQV@186801|Clostridia,25RAZ@186804|Peptostreptococcaceae	186801|Clostridia	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
PKFBPKFJ_00334	272563.CD630_33400	3.35e-116	332.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,25QZD@186804|Peptostreptococcaceae	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
PKFBPKFJ_00335	411902.CLOBOL_01205	7.05e-113	324.0	COG4734@1|root,COG4734@2|Bacteria,1VHFX@1239|Firmicutes,24QQM@186801|Clostridia,221Q5@1506553|Lachnoclostridium	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
PKFBPKFJ_00336	272563.CD630_33420	2.85e-114	328.0	2ETTS@1|root,33MB5@2|Bacteria,1VPEY@1239|Firmicutes,24SN2@186801|Clostridia	186801|Clostridia	S	Super-infection exclusion protein B	-	-	-	-	-	-	-	-	-	-	-	-	SieB
PKFBPKFJ_00337	1121115.AXVN01000067_gene3477	1.44e-42	139.0	2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,24N4I@186801|Clostridia,3Y0EY@572511|Blautia	186801|Clostridia	S	COG NOG13238 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00338	658086.HMPREF0994_05164	0.0	883.0	COG3620@1|root,COG3620@2|Bacteria,1TPHQ@1239|Firmicutes,249PB@186801|Clostridia,27UH8@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Replication initiation factor	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Rep_trans
PKFBPKFJ_00339	658086.HMPREF0994_05163	0.0	895.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,27K03@186928|unclassified Lachnospiraceae	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,FtsK_SpoIIIE
PKFBPKFJ_00340	658086.HMPREF0994_05162	4.71e-81	240.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,24IAF@186801|Clostridia,27NWZ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
PKFBPKFJ_00341	1121115.AXVN01000067_gene3473	1.94e-70	212.0	2BXTH@1|root,2ZZ52@2|Bacteria,1V3TU@1239|Firmicutes,24I3V@186801|Clostridia,3Y1NQ@572511|Blautia	186801|Clostridia	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
PKFBPKFJ_00342	411489.CLOL250_02400	1.07e-299	818.0	COG1106@1|root,COG1106@2|Bacteria,1UN3P@1239|Firmicutes,24DNQ@186801|Clostridia,36G3B@31979|Clostridiaceae	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
PKFBPKFJ_00343	411489.CLOL250_02399	2.08e-111	324.0	2AA5F@1|root,30ZEE@2|Bacteria,1V50A@1239|Firmicutes,248JH@186801|Clostridia,36QCH@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00344	411489.CLOL250_02398	8.9e-216	595.0	29X9P@1|root,30IZ8@2|Bacteria,1UJX8@1239|Firmicutes,24R4W@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00345	649747.HMPREF0083_00075	3.85e-90	268.0	28KKC@1|root,2ZA57@2|Bacteria,1V9NK@1239|Firmicutes,4HT6G@91061|Bacilli	91061|Bacilli	S	MTH538 TIR-like domain (DUF1863)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1863
PKFBPKFJ_00346	1280698.AUJS01000060_gene918	9.18e-49	155.0	2E5UB@1|root,30W42@2|Bacteria,1TUDK@1239|Firmicutes,25N6K@186801|Clostridia,27X5C@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00347	1280698.AUJS01000060_gene919	9.82e-45	144.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24SFQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00348	1280698.AUJS01000060_gene920	3.02e-36	122.0	2E5UB@1|root,30W4D@2|Bacteria,1VK7J@1239|Firmicutes,25N6S@186801|Clostridia,27X7V@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00349	1121115.AXVN01000067_gene3470	0.0	869.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,3Y01W@572511|Blautia	186801|Clostridia	T	subtilin biosynthesis sensor protein SpaK	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
PKFBPKFJ_00350	1121115.AXVN01000067_gene3469	1.02e-167	468.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,3XZUE@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_00351	1121115.AXVN01000067_gene3468	8.73e-81	240.0	2EQSU@1|root,33ICN@2|Bacteria,1VPW6@1239|Firmicutes,24WW2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00352	1121115.AXVN01000067_gene3467	1.34e-176	492.0	COG4200@1|root,COG4200@2|Bacteria,1V4AY@1239|Firmicutes,24EXR@186801|Clostridia,3Y0KJ@572511|Blautia	186801|Clostridia	S	Lantibiotic protection ABC transporter permease subunit, MutG family	mutG	-	-	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
PKFBPKFJ_00353	1121115.AXVN01000067_gene3466	3.54e-177	493.0	COG4200@1|root,COG4200@2|Bacteria,1V78D@1239|Firmicutes,25D9T@186801|Clostridia,3Y0R8@572511|Blautia	186801|Clostridia	S	ABC-2 family transporter protein	mutE	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
PKFBPKFJ_00354	457412.RSAG_01607	6.77e-162	454.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,3WHM4@541000|Ruminococcaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
PKFBPKFJ_00355	1121115.AXVN01000155_gene549	3.85e-17	75.1	296J0@1|root,2ZTUJ@2|Bacteria,1V3IP@1239|Firmicutes,24H9K@186801|Clostridia	186801|Clostridia	S	Bacterial mobilization protein MobC	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PKFBPKFJ_00356	1121115.AXVN01000155_gene550	7e-165	462.0	COG1051@1|root,COG1051@2|Bacteria,1VD3G@1239|Firmicutes,25MXE@186801|Clostridia,3Y20J@572511|Blautia	186801|Clostridia	F	NUDIX domain	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
PKFBPKFJ_00358	1280698.AUJS01000017_gene1837	1.4e-275	762.0	COG1522@1|root,COG2865@1|root,COG1522@2|Bacteria,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,27W54@189330|Dorea	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_11,HTH_24
PKFBPKFJ_00360	457412.RSAG_01585	4.91e-209	578.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,3WJ1R@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PKFBPKFJ_00361	457412.RSAG_01583	1.63e-63	194.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3WJWZ@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
PKFBPKFJ_00362	1121115.AXVN01000087_gene4052	0.0	1125.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,3XZ97@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 9.98	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
PKFBPKFJ_00363	1121115.AXVN01000048_gene1272	2.18e-154	434.0	COG0664@1|root,COG0664@2|Bacteria,1V2MV@1239|Firmicutes,24B7K@186801|Clostridia,3XZT1@572511|Blautia	186801|Clostridia	K	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PKFBPKFJ_00364	1121115.AXVN01000048_gene1273	9.39e-182	506.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia,3XZY2@572511|Blautia	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
PKFBPKFJ_00365	1121115.AXVN01000048_gene1274	3.61e-71	214.0	COG2865@1|root,COG2865@2|Bacteria,1VWB8@1239|Firmicutes,2513F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00366	1121115.AXVN01000048_gene1275	0.0	1889.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,SBP_bac_3
PKFBPKFJ_00367	1121115.AXVN01000048_gene1276	1.32e-61	188.0	2DZI1@1|root,32VB8@2|Bacteria,1VAA5@1239|Firmicutes,24KYU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00368	1121115.AXVN01000048_gene1277	2.41e-205	569.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3XZ6G@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
PKFBPKFJ_00369	1121115.AXVN01000048_gene1278	1.6e-189	528.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,3Y13H@572511|Blautia	186801|Clostridia	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr
PKFBPKFJ_00370	1121115.AXVN01000048_gene1279	1.23e-52	165.0	COG0425@1|root,COG0425@2|Bacteria,1VBET@1239|Firmicutes,24NV0@186801|Clostridia,3Y205@572511|Blautia	186801|Clostridia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
PKFBPKFJ_00371	457412.RSAG_01572	1.72e-69	209.0	COG0526@1|root,COG0526@2|Bacteria,1UG1U@1239|Firmicutes,24SF7@186801|Clostridia,3WKHR@541000|Ruminococcaceae	186801|Clostridia	O	Thioredoxin-like domain	-	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
PKFBPKFJ_00372	457412.RSAG_01571	3.42e-41	135.0	COG2104@1|root,COG2104@2|Bacteria,1VFJR@1239|Firmicutes,24SEU@186801|Clostridia,3WKGM@541000|Ruminococcaceae	186801|Clostridia	H	TIGRFAM thiamine biosynthesis protein ThiS	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
PKFBPKFJ_00373	1121115.AXVN01000048_gene1282	5.7e-198	548.0	COG0476@1|root,COG0476@2|Bacteria,1TQ3U@1239|Firmicutes,25CJC@186801|Clostridia,3Y0YS@572511|Blautia	186801|Clostridia	H	ThiF family	-	-	2.7.7.80	ko:K21029	ko04122,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	Rhodanese,ThiF
PKFBPKFJ_00374	457412.RSAG_01569	9.72e-103	296.0	COG1310@1|root,COG1310@2|Bacteria,1V6TY@1239|Firmicutes,24JI8@186801|Clostridia,3WJ1M@541000|Ruminococcaceae	186801|Clostridia	S	Mov34 MPN PAD-1 family	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
PKFBPKFJ_00375	457412.RSAG_01568	0.0	1110.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3WH9N@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,HisKA_7TM,Response_reg,SBP_bac_3
PKFBPKFJ_00376	1121115.AXVN01000048_gene1285	0.0	1033.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia	186801|Clostridia	G	Belongs to the GPI family	pgi	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
PKFBPKFJ_00377	1121115.AXVN01000048_gene1286	2.29e-211	585.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3Y2B1@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
PKFBPKFJ_00378	1121115.AXVN01000048_gene1287	8.96e-308	841.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3Y064@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 10.00	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
PKFBPKFJ_00379	1121115.AXVN01000048_gene1288	7.89e-245	672.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3XZ1P@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	oppD	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
PKFBPKFJ_00380	1121115.AXVN01000048_gene1289	3.5e-249	683.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3XZ61@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	appF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
PKFBPKFJ_00381	1121115.AXVN01000048_gene1290	0.0	1131.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,3Y0G8@572511|Blautia	186801|Clostridia	E	ABC transporter, substrate-binding protein, family 5	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
PKFBPKFJ_00382	1121115.AXVN01000048_gene1291	4.57e-124	352.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24KU4@186801|Clostridia,3Y2AC@572511|Blautia	186801|Clostridia	I	NUDIX domain	idi	-	-	-	-	-	-	-	-	-	-	-	NUDIX
PKFBPKFJ_00383	1458462.JNLK01000001_gene436	1.07e-09	62.4	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27I9U@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
PKFBPKFJ_00384	1121115.AXVN01000048_gene1292	3.76e-245	673.0	COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,25CDF@186801|Clostridia,3XYZU@572511|Blautia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
PKFBPKFJ_00385	1121115.AXVN01000048_gene1293	5.75e-141	398.0	COG0560@1|root,COG0560@2|Bacteria,1TQJY@1239|Firmicutes,2493S@186801|Clostridia,3Y0XF@572511|Blautia	186801|Clostridia	E	haloacid dehalogenase-like hydrolase	thrH	-	2.7.1.39,3.1.3.3	ko:K02203	ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00680,map01100,map01110,map01120,map01130,map01230	M00018	R00582,R01771	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HAD,Hydrolase
PKFBPKFJ_00386	1121115.AXVN01000048_gene1294	1.12e-116	334.0	COG1846@1|root,COG1846@2|Bacteria,1VEYN@1239|Firmicutes,24S21@186801|Clostridia,3Y0DP@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
PKFBPKFJ_00387	1121115.AXVN01000048_gene1295	0.0	1076.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XZEC@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PKFBPKFJ_00388	1121115.AXVN01000048_gene1296	0.0	1176.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XZBH@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PKFBPKFJ_00389	1121115.AXVN01000048_gene1297	1.66e-246	676.0	COG0523@1|root,COG0523@2|Bacteria,1TQRE@1239|Firmicutes,24B0I@186801|Clostridia,3Y16C@572511|Blautia	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
PKFBPKFJ_00390	457412.RSAG_01560	0.0	2149.0	COG1593@1|root,COG1638@1|root,COG1593@2|Bacteria,COG1638@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3WI33@541000|Ruminococcaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctP
PKFBPKFJ_00391	457412.RSAG_01559	7.62e-120	343.0	COG3090@1|root,COG3090@2|Bacteria,1VD6X@1239|Firmicutes,24QCX@186801|Clostridia	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
PKFBPKFJ_00392	1121115.AXVN01000108_gene621	5.83e-100	290.0	COG0346@1|root,COG0346@2|Bacteria,1V7XP@1239|Firmicutes,24KYI@186801|Clostridia,3Y0HK@572511|Blautia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
PKFBPKFJ_00393	457412.RSAG_01557	0.0	1152.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,24I15@186801|Clostridia,3WP5T@541000|Ruminococcaceae	186801|Clostridia	T	Cache domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
PKFBPKFJ_00394	1121115.AXVN01000108_gene623	0.0	1070.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,25B1H@186801|Clostridia,3Y2A1@572511|Blautia	186801|Clostridia	KT	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
PKFBPKFJ_00395	500632.CLONEX_01837	0.0	3591.0	COG0553@1|root,COG0827@1|root,COG3170@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG3170@2|Bacteria,COG4646@2|Bacteria,1TPQA@1239|Firmicutes,2491X@186801|Clostridia	186801|Clostridia	L	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	ResIII,SNF2_N
PKFBPKFJ_00396	1235792.C808_04781	9.36e-10	54.3	2CEPR@1|root,2ZSJ9@2|Bacteria,1W4DB@1239|Firmicutes,24USC@186801|Clostridia,27QGV@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00397	411459.RUMOBE_00621	2.72e-97	283.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,25BG6@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
PKFBPKFJ_00398	517417.Cpar_0789	1.09e-69	228.0	2EZMF@1|root,33SSK@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00399	411459.RUMOBE_00622	0.0	1088.0	COG4932@1|root,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,2492K@186801|Clostridia	186801|Clostridia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00400	411459.RUMOBE_00622	5.56e-68	229.0	COG4932@1|root,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,2492K@186801|Clostridia	186801|Clostridia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00401	471875.RUMLAC_02253	0.0	963.0	2DBAM@1|root,2Z83H@2|Bacteria,1TT4M@1239|Firmicutes,248DU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00403	471875.RUMLAC_02250	4.11e-75	225.0	2AJFI@1|root,31A1V@2|Bacteria,1V6VT@1239|Firmicutes,24KH5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00404	471875.RUMLAC_02249	5.37e-146	450.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,3WH3F@541000|Ruminococcaceae	186801|Clostridia	E	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail,TMP
PKFBPKFJ_00405	471875.RUMLAC_02249	1.37e-45	163.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,3WH3F@541000|Ruminococcaceae	186801|Clostridia	E	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail,TMP
PKFBPKFJ_00406	471875.RUMLAC_02249	1.62e-131	404.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,3WH3F@541000|Ruminococcaceae	186801|Clostridia	E	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail,TMP
PKFBPKFJ_00407	1280698.AUJS01000060_gene928	1.31e-114	329.0	COG0655@1|root,COG0655@2|Bacteria,1TSDE@1239|Firmicutes,24CNT@186801|Clostridia,27WEE@189330|Dorea	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
PKFBPKFJ_00408	471875.RUMLAC_02246	3.61e-75	225.0	2990R@1|root,2ZW4F@2|Bacteria,1V3SD@1239|Firmicutes,24HA5@186801|Clostridia,3WJGX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00409	471875.RUMLAC_02245	3.27e-142	402.0	28H7M@1|root,2Z7JU@2|Bacteria,1UG4F@1239|Firmicutes,24B1Y@186801|Clostridia,3WITV@541000|Ruminococcaceae	186801|Clostridia	S	phage major tail protein, phi13 family	-	-	-	-	-	-	-	-	-	-	-	-	Cadherin-like
PKFBPKFJ_00410	471875.RUMLAC_02244	5.99e-70	211.0	2CK6F@1|root,32SBP@2|Bacteria,1VA68@1239|Firmicutes,24NE8@186801|Clostridia,3WJTH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00411	471875.RUMLAC_02232	9.85e-98	289.0	COG3747@1|root,COG3747@2|Bacteria,1V0EC@1239|Firmicutes,24GCB@186801|Clostridia,3WJS0@541000|Ruminococcaceae	186801|Clostridia	L	Phage terminase, small subunit	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_4
PKFBPKFJ_00412	471875.RUMLAC_02231	9.05e-152	427.0	2E73X@1|root,31DXZ@2|Bacteria,1TV7A@1239|Firmicutes,259UI@186801|Clostridia,3WQQY@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00413	471875.RUMLAC_02230	6.07e-68	207.0	COG1403@1|root,COG1403@2|Bacteria,1V7XZ@1239|Firmicutes,24JNG@186801|Clostridia,3WK71@541000|Ruminococcaceae	186801|Clostridia	L	HNH endonuclease	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	HNH
PKFBPKFJ_00414	471875.RUMLAC_02229	2.61e-91	267.0	COG1191@1|root,COG1191@2|Bacteria,1V5CD@1239|Firmicutes,25DND@186801|Clostridia,3WKJ3@541000|Ruminococcaceae	186801|Clostridia	K	Protein of unknown function (DUF1492)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1492,Sigma70_r4
PKFBPKFJ_00415	471875.RUMLAC_02228	1.95e-28	103.0	2E3BF@1|root,32YAX@2|Bacteria,1VF9X@1239|Firmicutes,24SGT@186801|Clostridia,3WM68@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00416	471875.RUMLAC_02227	5.23e-55	180.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WH0A@541000|Ruminococcaceae	186801|Clostridia	L	helicase	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,SNF2_N
PKFBPKFJ_00417	471875.RUMLAC_02203	3.13e-40	140.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,3WHUC@541000|Ruminococcaceae	186801|Clostridia	K	chromosome partitioning protein K03497	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
PKFBPKFJ_00418	471875.RUMLAC_02201	9.45e-64	195.0	2DP3G@1|root,330D5@2|Bacteria,1VJYX@1239|Firmicutes,24RFF@186801|Clostridia	186801|Clostridia	S	Toxin SymE, type I toxin-antitoxin system	-	-	-	ko:K19048	-	-	-	-	ko00000,ko02048	-	-	-	SymE_toxin
PKFBPKFJ_00419	471875.RUMLAC_02200	3.12e-38	128.0	2EJE5@1|root,33D56@2|Bacteria,1VKA3@1239|Firmicutes,24WQ8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00420	1235793.C809_02170	1.96e-09	60.5	2DXV6@1|root,32V45@2|Bacteria,1VBYR@1239|Firmicutes,24P8R@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00422	457412.RSAG_00594	1.08e-252	696.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,25CD7@186801|Clostridia,3WGPH@541000|Ruminococcaceae	186801|Clostridia	P	Citrate transporter	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS
PKFBPKFJ_00423	457412.RSAG_00595	2.42e-192	532.0	COG0599@1|root,COG1917@1|root,COG0599@2|Bacteria,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,249JY@186801|Clostridia,3WGGH@541000|Ruminococcaceae	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	CMD,Cupin_2
PKFBPKFJ_00424	1121115.AXVN01000003_gene1577	8.05e-106	305.0	COG0716@1|root,COG0716@2|Bacteria,1V45R@1239|Firmicutes,24HDR@186801|Clostridia,3Y09P@572511|Blautia	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
PKFBPKFJ_00425	457412.RSAG_00597	8.47e-207	572.0	COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,248CX@186801|Clostridia,3WGE2@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_00426	1121115.AXVN01000003_gene1579	3.74e-69	209.0	COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,24NYY@186801|Clostridia,3Y09V@572511|Blautia	186801|Clostridia	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
PKFBPKFJ_00427	457412.RSAG_00599	0.0	1184.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,3WIA6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
PKFBPKFJ_00428	457412.RSAG_00600	2.07e-235	646.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,249GM@186801|Clostridia,3WGAM@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
PKFBPKFJ_00429	1121115.AXVN01000003_gene1582	6.14e-280	764.0	COG1820@1|root,COG1820@2|Bacteria,1UK3V@1239|Firmicutes,25FIQ@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation	iadA	-	-	ko:K01305	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Amidohydro_1,Amidohydro_3
PKFBPKFJ_00430	1121115.AXVN01000003_gene1583	0.0	967.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia	186801|Clostridia	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
PKFBPKFJ_00431	457412.RSAG_00603	1.53e-43	149.0	COG0317@1|root,COG0317@2|Bacteria,1TQW3@1239|Firmicutes,2483C@186801|Clostridia,3WH98@541000|Ruminococcaceae	186801|Clostridia	KT	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
PKFBPKFJ_00432	457412.RSAG_00603	8.88e-182	509.0	COG0317@1|root,COG0317@2|Bacteria,1TQW3@1239|Firmicutes,2483C@186801|Clostridia,3WH98@541000|Ruminococcaceae	186801|Clostridia	KT	Region found in RelA / SpoT proteins	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
PKFBPKFJ_00433	1121115.AXVN01000003_gene1585	1.41e-134	381.0	COG1116@1|root,COG1116@2|Bacteria,1VAD8@1239|Firmicutes,24GFE@186801|Clostridia,3Y1PX@572511|Blautia	186801|Clostridia	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
PKFBPKFJ_00434	1121115.AXVN01000003_gene1586	3.23e-176	492.0	COG0600@1|root,COG0600@2|Bacteria,1V73W@1239|Firmicutes,24A2R@186801|Clostridia,3Y1BD@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
PKFBPKFJ_00435	457412.RSAG_00606	5.4e-226	623.0	COG0715@1|root,COG0715@2|Bacteria,1TT2F@1239|Firmicutes,249M2@186801|Clostridia,3WHWJ@541000|Ruminococcaceae	186801|Clostridia	P	Menaquinone biosynthesis	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2,Phosphonate-bd,VitK2_biosynth
PKFBPKFJ_00436	457412.RSAG_00607	1.4e-200	555.0	COG4733@1|root,COG4733@2|Bacteria,1UICW@1239|Firmicutes,25EHW@186801|Clostridia	186801|Clostridia	S	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Glucosaminidase
PKFBPKFJ_00437	1121115.AXVN01000003_gene1589	2.32e-200	555.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3XZ53@572511|Blautia	186801|Clostridia	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
PKFBPKFJ_00438	457412.RSAG_00609	3.83e-139	394.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,3WJ4I@541000|Ruminococcaceae	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
PKFBPKFJ_00439	1121115.AXVN01000003_gene1591	4.83e-163	456.0	2C5Z2@1|root,32A20@2|Bacteria,1V5CS@1239|Firmicutes,24M7C@186801|Clostridia,3XZ4M@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
PKFBPKFJ_00440	457412.RSAG_00611	0.0	1287.0	COG1018@1|root,COG3894@1|root,COG1018@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3WI2J@541000|Ruminococcaceae	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
PKFBPKFJ_00441	457412.RSAG_00612	2.8e-185	515.0	COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3WNXA@541000|Ruminococcaceae	186801|Clostridia	E	Pterin binding enzyme	acsE	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
PKFBPKFJ_00442	457412.RSAG_00613	0.0	883.0	COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3WNR9@541000|Ruminococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsC	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
PKFBPKFJ_00443	457412.RSAG_00614	6.72e-215	594.0	COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3WNH3@541000|Ruminococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsD	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
PKFBPKFJ_00444	457412.RSAG_00615	0.0	1404.0	COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3WNGM@541000|Ruminococcaceae	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase complex beta subunit	cdhC	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
PKFBPKFJ_00445	1121115.AXVN01000003_gene1598	6.85e-178	496.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,3XZK1@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
PKFBPKFJ_00446	1121115.AXVN01000003_gene1599	0.0	1263.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,3XZEI@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	cooS1	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
PKFBPKFJ_00447	1121115.AXVN01000003_gene1600	1.83e-183	510.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,3XYPW@572511|Blautia	186801|Clostridia	D	cell division inhibitor, membrane ATPase MinD	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
PKFBPKFJ_00448	1121115.AXVN01000003_gene1601	1.02e-34	118.0	2FK7C@1|root,34BV3@2|Bacteria,1W6KA@1239|Firmicutes,254TZ@186801|Clostridia,3Y0MF@572511|Blautia	186801|Clostridia	S	Predicted RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RNA_bind_2
PKFBPKFJ_00449	457412.RSAG_00620	1.16e-68	209.0	2CEVS@1|root,30HAB@2|Bacteria,1UHCU@1239|Firmicutes,25Q3B@186801|Clostridia,3WR1K@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00450	457412.RSAG_00621	1.03e-203	563.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,3WHB2@541000|Ruminococcaceae	186801|Clostridia	S	Aldo keto reductases, related to diketogulonate reductase	yvgN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
PKFBPKFJ_00451	457412.RSAG_00622	9.5e-239	657.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,3WGZG@541000|Ruminococcaceae	186801|Clostridia	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
PKFBPKFJ_00452	1121115.AXVN01000003_gene1605	6.91e-149	419.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3XZ7V@572511|Blautia	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
PKFBPKFJ_00453	457412.RSAG_00624	2.91e-312	851.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,3WGNU@541000|Ruminococcaceae	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
PKFBPKFJ_00454	457412.RSAG_00625	0.0	917.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,3WGI9@541000|Ruminococcaceae	186801|Clostridia	C	FeS-containing Cyanobacterial-specific oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
PKFBPKFJ_00455	457412.RSAG_00626	8.77e-283	772.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3WGVK@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ribose-phosphate pyrophosphokinase family	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
PKFBPKFJ_00456	1121115.AXVN01000003_gene1609	1.12e-211	583.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,3XYQB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
PKFBPKFJ_00457	1121115.AXVN01000003_gene1610	3.51e-86	253.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,3Y0HI@572511|Blautia	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
PKFBPKFJ_00458	1121115.AXVN01000003_gene1611	1.38e-171	479.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3XZF8@572511|Blautia	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
PKFBPKFJ_00459	1121115.AXVN01000003_gene1612	1.46e-202	560.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,3XYWP@572511|Blautia	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
PKFBPKFJ_00460	457412.RSAG_00631	3.45e-138	391.0	COG0681@1|root,COG0681@2|Bacteria,1V2SF@1239|Firmicutes,24AWM@186801|Clostridia,3WRVN@541000|Ruminococcaceae	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
PKFBPKFJ_00461	1121115.AXVN01000003_gene1614	1.64e-74	223.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,3Y019@572511|Blautia	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
PKFBPKFJ_00462	1121115.AXVN01000003_gene1615	5.65e-220	606.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3XZRD@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
PKFBPKFJ_00463	1121115.AXVN01000003_gene1616	1.32e-187	525.0	COG2885@1|root,COG2885@2|Bacteria,1V6HB@1239|Firmicutes,24ARV@186801|Clostridia,3Y17K@572511|Blautia	186801|Clostridia	M	OmpA family	-	-	-	-	-	-	-	-	-	-	-	-	OmpA
PKFBPKFJ_00464	1121115.AXVN01000003_gene1617	0.0	1016.0	COG0497@1|root,COG0497@2|Bacteria,1UJV8@1239|Firmicutes,25FAU@186801|Clostridia	186801|Clostridia	U	MotA/TolQ/ExbB proton channel family	-	-	-	-	-	-	-	-	-	-	-	-	MotA_ExbB
PKFBPKFJ_00465	1121115.AXVN01000003_gene1618	9.19e-149	418.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24J27@186801|Clostridia,3Y2AD@572511|Blautia	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
PKFBPKFJ_00466	457412.RSAG_00637	0.0	1570.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3WHBB@541000|Ruminococcaceae	186801|Clostridia	J	phenylalanyl-tRNA synthetase (beta subunit)	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
PKFBPKFJ_00467	457412.RSAG_00638	5.78e-225	622.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3WGWV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
PKFBPKFJ_00468	1121115.AXVN01000003_gene1622	0.0	900.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3XZ00@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
PKFBPKFJ_00469	1121115.AXVN01000003_gene1623	6.8e-219	603.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,3XZM3@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
PKFBPKFJ_00470	1121115.AXVN01000003_gene1624	5.56e-166	465.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,3XZDI@572511|Blautia	186801|Clostridia	OU	Psort location Cytoplasmic, score 8.87	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
PKFBPKFJ_00471	1121115.AXVN01000003_gene1625	1.38e-167	469.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3XYGX@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
PKFBPKFJ_00472	457412.RSAG_00643	4.12e-310	845.0	COG1253@1|root,COG1253@2|Bacteria,1U77R@1239|Firmicutes,25CBE@186801|Clostridia,3WSC2@541000|Ruminococcaceae	186801|Clostridia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
PKFBPKFJ_00473	457412.RSAG_00644	1.2e-76	228.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,3WJE1@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
PKFBPKFJ_00474	1121115.AXVN01000003_gene1628	2.91e-277	758.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3XYKK@572511|Blautia	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
PKFBPKFJ_00475	457412.RSAG_00646	0.0	987.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3WG7J@541000|Ruminococcaceae	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
PKFBPKFJ_00476	1121115.AXVN01000003_gene1630	6.39e-150	422.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,3XZKT@572511|Blautia	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
PKFBPKFJ_00477	1121115.AXVN01000003_gene1631	0.0	1172.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3XYWT@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
PKFBPKFJ_00478	1121115.AXVN01000003_gene1632	6.59e-296	806.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,3XZ3V@572511|Blautia	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
PKFBPKFJ_00479	1121115.AXVN01000003_gene1633	4.04e-204	564.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,3XYHC@572511|Blautia	186801|Clostridia	O	Psort location Extracellular, score	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
PKFBPKFJ_00480	457412.RSAG_04750	3.94e-30	106.0	28RQE@1|root,2ZE30@2|Bacteria,1W6E6@1239|Firmicutes,254WA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00481	1121115.AXVN01000003_gene1635	1.14e-175	489.0	COG0500@1|root,COG0500@2|Bacteria,1UKI1@1239|Firmicutes,25FXJ@186801|Clostridia	186801|Clostridia	Q	Specifically methylates the guanosine in position 1516 of 16S rRNA	rsmJ	-	-	-	-	-	-	-	-	-	-	-	SAM_MT
PKFBPKFJ_00482	1121115.AXVN01000003_gene1636	0.0	1004.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,249HE@186801|Clostridia,3XZ8V@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
PKFBPKFJ_00483	1121115.AXVN01000003_gene1638	8.23e-160	447.0	COG2315@1|root,COG3695@1|root,COG2315@2|Bacteria,COG3695@2|Bacteria,1VVT6@1239|Firmicutes,25EAU@186801|Clostridia,3Y0FV@572511|Blautia	186801|Clostridia	L	YjbR	ogt	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,YjbR
PKFBPKFJ_00485	1121115.AXVN01000003_gene1639	6.65e-126	358.0	COG5279@1|root,COG5279@2|Bacteria,1UT8R@1239|Firmicutes,24CQF@186801|Clostridia,3Y1E1@572511|Blautia	186801|Clostridia	D	protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PKFBPKFJ_00486	1121115.AXVN01000002_gene1446	0.0	1266.0	COG1680@1|root,COG1680@2|Bacteria,1W747@1239|Firmicutes,256Q7@186801|Clostridia,3Y0WX@572511|Blautia	2|Bacteria	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
PKFBPKFJ_00487	457412.RSAG_00083	3.51e-309	843.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
PKFBPKFJ_00488	457412.RSAG_00082	1.3e-262	725.0	COG4219@1|root,COG4219@2|Bacteria,1V0EY@1239|Firmicutes,24EI3@186801|Clostridia	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
PKFBPKFJ_00489	1121115.AXVN01000002_gene1443	5.21e-63	194.0	2FAVS@1|root,3432X@2|Bacteria,1VXAQ@1239|Firmicutes,2520G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00490	1121115.AXVN01000002_gene1442	5.29e-54	169.0	COG2608@1|root,COG2608@2|Bacteria,1VETC@1239|Firmicutes,24QJU@186801|Clostridia	186801|Clostridia	P	mercury ion transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	HMA
PKFBPKFJ_00491	1121115.AXVN01000002_gene1441	2.56e-269	748.0	COG3976@1|root,COG3976@2|Bacteria,1TR5A@1239|Firmicutes,25E6J@186801|Clostridia,3Y15H@572511|Blautia	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,Fer4_5
PKFBPKFJ_00492	457412.RSAG_00077	0.0	1125.0	COG5492@1|root,COG5492@2|Bacteria,1UK32@1239|Firmicutes,25FHP@186801|Clostridia	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,FIVAR,PBP-Tp47_a,PBP-Tp47_c
PKFBPKFJ_00493	457412.RSAG_00076	8.23e-247	677.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3WGXU@541000|Ruminococcaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
PKFBPKFJ_00494	457412.RSAG_00075	4.17e-190	527.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3WIWA@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_5
PKFBPKFJ_00495	1121115.AXVN01000002_gene1437	8.97e-96	283.0	COG3976@1|root,COG3976@2|Bacteria,1VT26@1239|Firmicutes,25BMN@186801|Clostridia	186801|Clostridia	S	FMN_bind	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
PKFBPKFJ_00496	1121115.AXVN01000002_gene1436	0.0	1149.0	COG5492@1|root,COG5492@2|Bacteria,1UKHW@1239|Firmicutes,25FXE@186801|Clostridia	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
PKFBPKFJ_00497	1121115.AXVN01000002_gene1435	3.61e-95	279.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,3Y096@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
PKFBPKFJ_00498	1121115.AXVN01000002_gene1434	3.01e-77	230.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3Y0CQ@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
PKFBPKFJ_00499	457412.RSAG_00070	0.0	1169.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3WG9Y@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
PKFBPKFJ_00500	1121115.AXVN01000002_gene1432	2.41e-45	146.0	COG2608@1|root,COG2608@2|Bacteria,1VEM6@1239|Firmicutes,24QS3@186801|Clostridia,3Y0J0@572511|Blautia	186801|Clostridia	P	Heavy-metal-associated domain	-	-	-	-	-	-	-	-	-	-	-	-	HMA
PKFBPKFJ_00501	457412.RSAG_00068	1.33e-87	257.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3WK31@541000|Ruminococcaceae	186801|Clostridia	K	iron dependent repressor	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
PKFBPKFJ_00502	1121115.AXVN01000002_gene1430	0.0	1313.0	COG2217@1|root,COG2217@2|Bacteria,1TPB8@1239|Firmicutes,247RZ@186801|Clostridia,3XYS4@572511|Blautia	186801|Clostridia	P	COG COG2217 Cation transport ATPase	copA_1	-	-	ko:K12950	-	-	-	-	ko00000,ko01000	3.A.3.32	-	-	E1-E2_ATPase,Hydrolase
PKFBPKFJ_00503	1121115.AXVN01000002_gene1429	1.98e-46	152.0	2E5VW@1|root,330JY@2|Bacteria,1VEZ5@1239|Firmicutes,24R14@186801|Clostridia,3Y0EI@572511|Blautia	186801|Clostridia	S	H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00504	457412.RSAG_00065	6.61e-110	316.0	COG0735@1|root,COG0735@2|Bacteria,1V6DP@1239|Firmicutes,24K9H@186801|Clostridia,3WM1R@541000|Ruminococcaceae	186801|Clostridia	L	Ferric uptake regulator family	fur	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
PKFBPKFJ_00505	1410632.JHWW01000021_gene418	3.44e-11	58.5	2DRWB@1|root,33DDT@2|Bacteria,1VKGH@1239|Firmicutes,24VWG@186801|Clostridia,27PQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Virus attachment protein p12 family	-	-	-	-	-	-	-	-	-	-	-	-	P12
PKFBPKFJ_00506	1121115.AXVN01000002_gene1427	0.0	1423.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3XZAE@572511|Blautia	186801|Clostridia	P	Ferrous iron transport protein B	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
PKFBPKFJ_00507	457412.RSAG_00061	3.97e-43	141.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,3WKEJ@541000|Ruminococcaceae	186801|Clostridia	P	Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
PKFBPKFJ_00508	457412.RSAG_00060	7.14e-39	129.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,3WKEV@541000|Ruminococcaceae	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
PKFBPKFJ_00509	1121115.AXVN01000002_gene1424	4.54e-63	192.0	2DMMF@1|root,32SEK@2|Bacteria,1VAB3@1239|Firmicutes,24N8S@186801|Clostridia,3Y0F2@572511|Blautia	186801|Clostridia	S	COG NOG21970 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF2325
PKFBPKFJ_00510	1121115.AXVN01000002_gene1423	3.65e-293	800.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia,3XZ1Y@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
PKFBPKFJ_00511	1121115.AXVN01000002_gene1422	0.0	945.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,3XYRP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
PKFBPKFJ_00512	1121115.AXVN01000002_gene1421	5.46e-259	709.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,3XZNK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
PKFBPKFJ_00513	1121115.AXVN01000002_gene1420	1.91e-47	152.0	COG0864@1|root,COG0864@2|Bacteria,1VF9M@1239|Firmicutes,24QVJ@186801|Clostridia,3Y0MU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00514	457412.RSAG_00054	1.4e-238	655.0	2DUPT@1|root,33RMR@2|Bacteria,1UKHV@1239|Firmicutes,25FXD@186801|Clostridia	186801|Clostridia	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PKFBPKFJ_00515	1121115.AXVN01000002_gene1418	3.5e-218	600.0	COG0152@1|root,COG0152@2|Bacteria,1UF8J@1239|Firmicutes,25K96@186801|Clostridia,3XZ70@572511|Blautia	186801|Clostridia	F	Belongs to the SAICAR synthetase family	purC	-	6.3.2.6	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04591	RC00064,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
PKFBPKFJ_00516	1121115.AXVN01000002_gene1417	0.0	1008.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3XZ0V@572511|Blautia	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
PKFBPKFJ_00517	457412.RSAG_00051	2.54e-84	248.0	COG5341@1|root,COG5341@2|Bacteria,1UQFQ@1239|Firmicutes,25873@186801|Clostridia,3WM3Y@541000|Ruminococcaceae	186801|Clostridia	S	NusG domain II	-	-	-	-	-	-	-	-	-	-	-	-	NusG_II
PKFBPKFJ_00518	457412.RSAG_00050	0.0	901.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia,3WSIQ@541000|Ruminococcaceae	186801|Clostridia	S	ATPase. Has a role at an early stage in the morphogenesis of the spore coat	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
PKFBPKFJ_00519	457412.RSAG_00049	0.0	1147.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,3WGMQ@541000|Ruminococcaceae	186801|Clostridia	C	hydrogenase large subunit	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,NADH-G_4Fe-4S_3
PKFBPKFJ_00520	1121115.AXVN01000002_gene1413	0.0	1226.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3XZ6P@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
PKFBPKFJ_00521	1121115.AXVN01000002_gene1412	4.82e-113	324.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,3XZET@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
PKFBPKFJ_00522	457412.RSAG_00046	1.29e-167	468.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia,3WIT8@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
PKFBPKFJ_00523	1121115.AXVN01000002_gene1410	7.64e-131	371.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,3XZI9@572511|Blautia	186801|Clostridia	C	COG COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
PKFBPKFJ_00524	457412.RSAG_00044	8.18e-208	573.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3WH30@541000|Ruminococcaceae	186801|Clostridia	C	Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
PKFBPKFJ_00525	457412.RSAG_00043	0.0	1070.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WHXW@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain	-	-	1.3.5.1,1.3.5.4,1.3.99.33	ko:K00239,ko:K00244,ko:K17363	ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164,R10330	RC00045,RC00669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,FMN_red
PKFBPKFJ_00526	1121115.AXVN01000002_gene1407	3.15e-163	456.0	COG4656@1|root,COG4656@2|Bacteria,1UY26@1239|Firmicutes,24D3I@186801|Clostridia,3Y0XC@572511|Blautia	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_7,Fer4_9
PKFBPKFJ_00527	1121115.AXVN01000002_gene1406	1.87e-215	593.0	COG0543@1|root,COG0543@2|Bacteria,1TQBZ@1239|Firmicutes,248GQ@186801|Clostridia,3Y1HE@572511|Blautia	186801|Clostridia	CH	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
PKFBPKFJ_00528	1121115.AXVN01000002_gene1405	1.45e-260	712.0	COG0479@1|root,COG0479@2|Bacteria,1TP8R@1239|Firmicutes,247QI@186801|Clostridia,3Y1ET@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
PKFBPKFJ_00529	1121115.AXVN01000002_gene1404	9.19e-243	665.0	COG1035@1|root,COG4656@1|root,COG1035@2|Bacteria,COG4656@2|Bacteria,1TPBM@1239|Firmicutes,24CJH@186801|Clostridia,3Y13N@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,FrhB_FdhB_C
PKFBPKFJ_00530	1121115.AXVN01000002_gene1403	5.15e-109	313.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,3Y10T@572511|Blautia	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
PKFBPKFJ_00531	1121115.AXVN01000002_gene1402	0.0	1292.0	COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,3Y0ZT@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,Pyr_redox_2
PKFBPKFJ_00532	1121115.AXVN01000002_gene1401	1.89e-91	267.0	COG1150@1|root,COG1150@2|Bacteria,1V27J@1239|Firmicutes,24FU5@186801|Clostridia,3Y1I7@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8
PKFBPKFJ_00533	1121115.AXVN01000002_gene1400	2.51e-197	546.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia,3Y1B6@572511|Blautia	186801|Clostridia	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
PKFBPKFJ_00534	1121115.AXVN01000002_gene1399	2.86e-217	600.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3XZ3D@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
PKFBPKFJ_00535	1121115.AXVN01000002_gene1398	9.38e-317	863.0	COG2966@1|root,COG3610@1|root,COG2966@2|Bacteria,COG3610@2|Bacteria,1TNZH@1239|Firmicutes,24BQZ@186801|Clostridia,3Y170@572511|Blautia	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
PKFBPKFJ_00536	1121115.AXVN01000002_gene1397	1.02e-194	539.0	28JZH@1|root,2Z9PI@2|Bacteria,1V0QF@1239|Firmicutes,248FG@186801|Clostridia,3Y1MC@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4866
PKFBPKFJ_00537	1121115.AXVN01000002_gene1396	0.0	1070.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PKFBPKFJ_00538	1121115.AXVN01000002_gene1395	1.29e-28	110.0	COG2931@1|root,COG2931@2|Bacteria,1TSGB@1239|Firmicutes,247TS@186801|Clostridia,3Y1XR@572511|Blautia	186801|Clostridia	Q	Collagen triple helix repeat (20 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Collagen
PKFBPKFJ_00539	1121115.AXVN01000002_gene1394	8.52e-273	744.0	COG0463@1|root,COG0463@2|Bacteria,1TQEM@1239|Firmicutes,249HH@186801|Clostridia,3XZ06@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	sunS	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,TPR_8
PKFBPKFJ_00540	1121115.AXVN01000002_gene1393	0.0	1203.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3XZNF@572511|Blautia	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
PKFBPKFJ_00541	457412.RSAG_00028	0.0	1025.0	COG4733@1|root,COG5279@1|root,COG4733@2|Bacteria,COG5279@2|Bacteria,1V1JE@1239|Firmicutes,24GTB@186801|Clostridia,3WK9S@541000|Ruminococcaceae	186801|Clostridia	D	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00542	1121115.AXVN01000002_gene1391	2.51e-56	175.0	2F99N@1|root,340RC@2|Bacteria,1VX34@1239|Firmicutes,257JQ@186801|Clostridia,3Y26Y@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00543	1121115.AXVN01000002_gene1390	3.21e-178	496.0	COG0463@1|root,COG0463@2|Bacteria,1TRRK@1239|Firmicutes,24CHM@186801|Clostridia,3Y03K@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PKFBPKFJ_00544	457412.RSAG_00025	3.81e-275	753.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,3WHJY@541000|Ruminococcaceae	186801|Clostridia	HP	ATPases associated with a variety of cellular activities	fepC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran,zf-like
PKFBPKFJ_00545	1121115.AXVN01000002_gene1388	2.56e-227	628.0	COG0609@1|root,COG0609@2|Bacteria,1TQXW@1239|Firmicutes,249TJ@186801|Clostridia,3Y151@572511|Blautia	186801|Clostridia	P	FecCD transport family	btuC	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
PKFBPKFJ_00546	457412.RSAG_00023	1.65e-286	782.0	COG0614@1|root,COG0614@2|Bacteria,1TQ4U@1239|Firmicutes,249I2@186801|Clostridia,3WHGS@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
PKFBPKFJ_00547	457412.RSAG_00022	1.86e-197	552.0	COG0614@1|root,COG5386@1|root,COG0614@2|Bacteria,COG5386@2|Bacteria,1UYC0@1239|Firmicutes,24D7G@186801|Clostridia,3WSRF@541000|Ruminococcaceae	186801|Clostridia	M	Cell surface protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00548	457412.RSAG_00021	6.13e-276	762.0	COG4822@1|root,COG4822@2|Bacteria,1TQ5V@1239|Firmicutes,24ABG@186801|Clostridia,3WGQC@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	cbiK	-	4.99.1.3	ko:K02190	ko00860,ko01100,map00860,map01100	-	R05807	RC01012	ko00000,ko00001,ko01000	-	-	-	CbiK
PKFBPKFJ_00549	1121115.AXVN01000002_gene1383	2.6e-81	240.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,3XZDT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
PKFBPKFJ_00550	1121115.AXVN01000002_gene1382	3.22e-140	395.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,3XYJ4@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
PKFBPKFJ_00551	1121115.AXVN01000002_gene1381	6.73e-303	827.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,3XZ14@572511|Blautia	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
PKFBPKFJ_00552	1121115.AXVN01000002_gene1380	1.76e-147	416.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia,3XZ1U@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
PKFBPKFJ_00553	1121115.AXVN01000002_gene1379	1.77e-262	719.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,3XYWI@572511|Blautia	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
PKFBPKFJ_00554	457412.RSAG_00015	5.06e-126	358.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia,3WIFA@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
PKFBPKFJ_00555	1121115.AXVN01000002_gene1377	6.57e-107	310.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3XZX6@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
PKFBPKFJ_00556	1121115.AXVN01000002_gene1376	2.18e-245	674.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,3XYMC@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PKFBPKFJ_00557	457412.RSAG_00012	1.83e-150	423.0	2E2IE@1|root,32XN3@2|Bacteria,1VD21@1239|Firmicutes,24KKS@186801|Clostridia,3WM0H@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00558	1121115.AXVN01000002_gene1374	0.0	1288.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,3XYGY@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
PKFBPKFJ_00559	1121115.AXVN01000002_gene1373	2.49e-188	523.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,3XZGG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yjbM	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
PKFBPKFJ_00560	1121115.AXVN01000002_gene1372	0.0	951.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia,3XZA8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
PKFBPKFJ_00561	457412.RSAG_00008	6.8e-221	609.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia,3WIGE@541000|Ruminococcaceae	186801|Clostridia	S	sporulation integral membrane protein YlbJ	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
PKFBPKFJ_00562	1121115.AXVN01000002_gene1370	2.51e-94	281.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,3XZBA@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00563	1121115.AXVN01000002_gene1369	1.66e-111	320.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,3XZXZ@572511|Blautia	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
PKFBPKFJ_00564	1121115.AXVN01000002_gene1368	4.62e-125	356.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3XZUU@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
PKFBPKFJ_00565	1121115.AXVN01000002_gene1367	1.27e-90	265.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3Y038@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
PKFBPKFJ_00566	457412.RSAG_00003	2.31e-69	209.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia,3WKRS@541000|Ruminococcaceae	186801|Clostridia	S	Small, acid-soluble spore protein, alpha beta type	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
PKFBPKFJ_00568	658655.HMPREF0988_01964	1.06e-21	94.4	COG1476@1|root,COG1476@2|Bacteria,1V67J@1239|Firmicutes,25IMU@186801|Clostridia,27SF4@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_00569	478749.BRYFOR_09292	0.0	924.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PKFBPKFJ_00570	1121115.AXVN01000034_gene3876	3.82e-24	102.0	COG2199@1|root,COG4684@1|root,COG2199@2|Bacteria,COG4684@2|Bacteria	2|Bacteria	S	ECF transporter, substrate-specific component	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	EAL,ECF_trnsprt,GGDEF,HATPase_c,HisKA,PAS_3
PKFBPKFJ_00571	1121115.AXVN01000060_gene468	2.72e-27	101.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3XYNT@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
PKFBPKFJ_00572	457412.RSAG_02506	0.0	1025.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3WHUY@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 32 family	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
PKFBPKFJ_00573	1121115.AXVN01000060_gene470	0.0	1140.0	COG1653@1|root,COG1653@2|Bacteria,1TS6D@1239|Firmicutes,248CI@186801|Clostridia,3XZ5C@572511|Blautia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	SBP_bac_1,SBP_bac_8,TAT_signal
PKFBPKFJ_00574	1121115.AXVN01000060_gene471	3.2e-209	578.0	COG0395@1|root,COG0395@2|Bacteria,1TQ9F@1239|Firmicutes,24846@186801|Clostridia,3XZ22@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PKFBPKFJ_00575	457412.RSAG_02509	4.41e-219	605.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,248XU@186801|Clostridia,3WHDQ@541000|Ruminococcaceae	186801|Clostridia	P	carbohydrate ABC transporter membrane protein 1 CUT1 family	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PKFBPKFJ_00576	1121115.AXVN01000060_gene474	6.15e-236	650.0	COG1609@1|root,COG1609@2|Bacteria,1TSU0@1239|Firmicutes,24C3S@186801|Clostridia,3XZBF@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
PKFBPKFJ_00577	500632.CLONEX_03326	2.98e-06	48.1	COG0110@1|root,COG0110@2|Bacteria,1V06U@1239|Firmicutes,25BGT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
PKFBPKFJ_00579	457412.RSAG_02512	0.0	1001.0	COG3669@1|root,COG3669@2|Bacteria,1TSG7@1239|Firmicutes,247VJ@186801|Clostridia,3WNXK@541000|Ruminococcaceae	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos,Calx-beta,F5_F8_type_C,FIVAR,Gram_pos_anchor
PKFBPKFJ_00580	1121115.AXVN01000060_gene478	6.33e-189	525.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3XZD4@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10202	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
PKFBPKFJ_00581	457412.RSAG_02514	7.73e-199	552.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WI95@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10201	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	BPD_transp_1
PKFBPKFJ_00582	457412.RSAG_02515	0.0	884.0	COG1653@1|root,COG1653@2|Bacteria,1TRWM@1239|Firmicutes,24AP7@186801|Clostridia,3WHFF@541000|Ruminococcaceae	186801|Clostridia	G	Carbohydrate ABC transporter	-	-	-	ko:K10200	ko02010,map02010	M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18	-	-	SBP_bac_8,TAT_signal
PKFBPKFJ_00583	457412.RSAG_02516	0.0	1159.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,24EC1@186801|Clostridia,3WNN0@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
PKFBPKFJ_00584	457412.RSAG_02517	3.05e-280	766.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V48A@1239|Firmicutes,24GUP@186801|Clostridia,3WRJR@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
PKFBPKFJ_00585	457412.RSAG_02518	0.0	1577.0	COG1554@1|root,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,248K8@186801|Clostridia,3WH2C@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,F5_F8_type_C,Glyco_hyd_65N_2
PKFBPKFJ_00586	518637.EUBIFOR_00794	3.97e-146	416.0	COG2200@1|root,COG2200@2|Bacteria	2|Bacteria	T	EAL domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,EAL,GGDEF
PKFBPKFJ_00587	457412.RSAG_02521	1.26e-178	499.0	COG0348@1|root,COG0348@2|Bacteria,1TRZZ@1239|Firmicutes,24A2P@186801|Clostridia,3WNCH@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5,Fer4_9
PKFBPKFJ_00588	457412.RSAG_02522	4.21e-131	372.0	COG1102@1|root,COG1102@2|Bacteria,1UXGP@1239|Firmicutes,259Y0@186801|Clostridia,3WQJG@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
PKFBPKFJ_00589	1121115.AXVN01000163_gene908	1.68e-108	312.0	COG0454@1|root,COG0456@2|Bacteria,1V1VV@1239|Firmicutes,25CUX@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PKFBPKFJ_00590	1121115.AXVN01000163_gene909	7.78e-284	774.0	COG3550@1|root,COG3550@2|Bacteria,1TR9A@1239|Firmicutes,24C9K@186801|Clostridia,3Y049@572511|Blautia	186801|Clostridia	S	HipA-like C-terminal domain	-	-	2.7.11.1	ko:K07154	-	-	-	-	ko00000,ko01000,ko01001,ko02048	-	-	-	Couple_hipA,HipA_C
PKFBPKFJ_00591	1121115.AXVN01000163_gene910	5.98e-55	172.0	COG1396@1|root,COG1396@2|Bacteria,1VARC@1239|Firmicutes,24NFJ@186801|Clostridia,3Y0DI@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_00592	457412.RSAG_02526	2.02e-137	388.0	COG1309@1|root,COG1309@2|Bacteria,1VGCX@1239|Firmicutes,24G4C@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
PKFBPKFJ_00593	457412.RSAG_02527	0.0	999.0	COG1022@1|root,COG1022@2|Bacteria,1V0YG@1239|Firmicutes,25E9H@186801|Clostridia,3WI3M@541000|Ruminococcaceae	186801|Clostridia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
PKFBPKFJ_00594	1121115.AXVN01000008_gene2658	8.84e-43	140.0	2DP4E@1|root,330GX@2|Bacteria,1VEZ7@1239|Firmicutes,24SE1@186801|Clostridia,3Y0WR@572511|Blautia	186801|Clostridia	Q	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
PKFBPKFJ_00595	1121115.AXVN01000008_gene2659	0.0	954.0	COG1020@1|root,COG1020@2|Bacteria,1TQP2@1239|Firmicutes,24AMK@186801|Clostridia,3Y0AJ@572511|Blautia	186801|Clostridia	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
PKFBPKFJ_00596	457412.RSAG_02530	6.76e-247	676.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,3WK39@541000|Ruminococcaceae	186801|Clostridia	S	Serine aminopeptidase, S33	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4,Peptidase_S9
PKFBPKFJ_00597	411461.DORFOR_02067	2.7e-193	540.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia,27VKR@189330|Dorea	186801|Clostridia	EG	COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PKFBPKFJ_00598	1121115.AXVN01000008_gene2662	6.12e-40	132.0	COG4608@1|root,COG4608@2|Bacteria,1W0U9@1239|Firmicutes,252YQ@186801|Clostridia	186801|Clostridia	E	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00599	1121115.AXVN01000008_gene2663	2.12e-192	535.0	COG2510@1|root,COG2510@2|Bacteria,1V3VG@1239|Firmicutes,247SX@186801|Clostridia,3XZSJ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
PKFBPKFJ_00600	457412.RSAG_02534	1.65e-153	430.0	COG2819@1|root,COG2819@2|Bacteria,1V1TT@1239|Firmicutes,24GDE@186801|Clostridia,3WIMM@541000|Ruminococcaceae	186801|Clostridia	S	hydrolase of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
PKFBPKFJ_00601	1121115.AXVN01000008_gene2665	3.41e-296	809.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,3XYV4@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
PKFBPKFJ_00602	1121115.AXVN01000008_gene2666	2.46e-199	555.0	COG0679@1|root,COG0679@2|Bacteria,1UYFH@1239|Firmicutes,24AI3@186801|Clostridia,3Y2CN@572511|Blautia	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
PKFBPKFJ_00603	1121115.AXVN01000008_gene2667	3.5e-116	333.0	COG1611@1|root,COG1611@2|Bacteria,1UKED@1239|Firmicutes,24DSN@186801|Clostridia	186801|Clostridia	L	Belongs to the LOG family	yvdD	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
PKFBPKFJ_00604	478749.BRYFOR_09258	4.94e-116	336.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
PKFBPKFJ_00605	457412.RSAG_01544	8.9e-219	607.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WI8G@541000|Ruminococcaceae	186801|Clostridia	H	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
PKFBPKFJ_00606	457412.RSAG_01545	0.0	1100.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3WGPR@541000|Ruminococcaceae	186801|Clostridia	EG	Belongs to the IlvD Edd family	ilvD3	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PKFBPKFJ_00607	515620.EUBELI_20204	5.38e-27	100.0	2DPN0@1|root,332QI@2|Bacteria,1VH4E@1239|Firmicutes,24R2M@186801|Clostridia	186801|Clostridia	S	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00608	515620.EUBELI_20205	2.47e-270	746.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia,25WGH@186806|Eubacteriaceae	186801|Clostridia	EG	gluconate H symporter	-	-	-	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.4,2.A.8.1.8	-	iHN637.CLJU_RS05690,iHN637.CLJU_RS13905	GntP_permease
PKFBPKFJ_00609	411470.RUMGNA_01947	1e-111	326.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia,3Y01S@572511|Blautia	186801|Clostridia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PKFBPKFJ_00610	1121115.AXVN01000008_gene2671	5.84e-174	486.0	COG4608@1|root,COG4608@2|Bacteria,1UV6D@1239|Firmicutes,25BCP@186801|Clostridia	186801|Clostridia	E	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PKFBPKFJ_00611	457412.RSAG_02544	1.32e-176	494.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,24B9N@186801|Clostridia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PKFBPKFJ_00612	1121115.AXVN01000008_gene2673	0.0	1014.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3XZGV@572511|Blautia	186801|Clostridia	E	Psort location Cellwall, score	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PKFBPKFJ_00613	1121115.AXVN01000008_gene2674	7.99e-194	539.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZRV@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
PKFBPKFJ_00614	1121115.AXVN01000008_gene2675	4.64e-206	572.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZG8@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PKFBPKFJ_00615	1121115.AXVN01000008_gene2676	1.76e-216	598.0	COG0583@1|root,COG0583@2|Bacteria,1V5MW@1239|Firmicutes,24J0X@186801|Clostridia,3Y0IH@572511|Blautia	186801|Clostridia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1
PKFBPKFJ_00616	457412.RSAG_02550	8.63e-296	811.0	COG2239@1|root,COG2239@2|Bacteria,1TP4V@1239|Firmicutes,2481R@186801|Clostridia,3WG82@541000|Ruminococcaceae	186801|Clostridia	P	Acts as a magnesium transporter	mgtE	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE,MgtE_N
PKFBPKFJ_00617	1121115.AXVN01000008_gene2679	3.16e-158	443.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia,3XZ6R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
PKFBPKFJ_00618	1121115.AXVN01000008_gene2680	5.67e-199	552.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,3XYU6@572511|Blautia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
PKFBPKFJ_00619	457412.RSAG_02553	2.61e-147	415.0	COG2364@1|root,COG2364@2|Bacteria,1V1ZQ@1239|Firmicutes,24GEW@186801|Clostridia,3WRWZ@541000|Ruminococcaceae	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	YitT_membrane
PKFBPKFJ_00620	1121115.AXVN01000008_gene2682	3.52e-253	695.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3XZ5V@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
PKFBPKFJ_00621	1121115.AXVN01000008_gene2683	3.04e-154	433.0	COG3341@1|root,COG3341@2|Bacteria,1UIS0@1239|Firmicutes,25EQZ@186801|Clostridia	186801|Clostridia	L	Caulimovirus viroplasmin	rnhA	-	-	ko:K06993	-	-	-	-	ko00000	-	-	-	Cauli_VI,RNase_H
PKFBPKFJ_00622	1121115.AXVN01000008_gene2684	9.6e-269	737.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3Y04D@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R04880,R05233,R05234,R06917,R06927	RC00050,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
PKFBPKFJ_00623	457412.RSAG_02563	0.0	978.0	COG0531@1|root,COG0531@2|Bacteria,1TQ4K@1239|Firmicutes,25E7A@186801|Clostridia,3WHIY@541000|Ruminococcaceae	186801|Clostridia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
PKFBPKFJ_00624	1121115.AXVN01000008_gene2686	3.86e-142	401.0	COG1102@1|root,COG1102@2|Bacteria,1V74C@1239|Firmicutes,24EKT@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
PKFBPKFJ_00625	457412.RSAG_02565	7.77e-301	819.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3WGQA@541000|Ruminococcaceae	186801|Clostridia	E	acetylornithine aminotransferase	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PKFBPKFJ_00626	457412.RSAG_02566	6.85e-132	374.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V5G6@1239|Firmicutes,24928@186801|Clostridia,3WKCT@541000|Ruminococcaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
PKFBPKFJ_00627	1121115.AXVN01000008_gene2688	0.0	1127.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3XZCN@572511|Blautia	186801|Clostridia	H	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PKFBPKFJ_00628	457412.RSAG_02568	9.88e-111	319.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia,3WJE7@541000|Ruminococcaceae	186801|Clostridia	E	Small subunit of acetolactate synthase	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
PKFBPKFJ_00629	457412.RSAG_02569	9.54e-304	828.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3WGV5@541000|Ruminococcaceae	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
PKFBPKFJ_00630	457412.RSAG_02570	2.59e-169	473.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,3WIW2@541000|Ruminococcaceae	186801|Clostridia	E	PHP domain protein	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
PKFBPKFJ_00631	1121115.AXVN01000008_gene2689	2e-74	225.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia,3XZ1J@572511|Blautia	186801|Clostridia	E	COG COG0440 Acetolactate synthase, small (regulatory) subunit	ilvH_1	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
PKFBPKFJ_00632	1121115.AXVN01000008_gene2712	8.49e-128	365.0	COG4684@1|root,COG4684@2|Bacteria,1V2M1@1239|Firmicutes,249YQ@186801|Clostridia,3XZCZ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
PKFBPKFJ_00633	1121115.AXVN01000008_gene2713	4.1e-224	618.0	COG3191@1|root,COG3191@2|Bacteria,1TP60@1239|Firmicutes,24AVR@186801|Clostridia,3XZ5P@572511|Blautia	186801|Clostridia	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
PKFBPKFJ_00634	1121115.AXVN01000008_gene2690	1.94e-32	123.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3XYYM@572511|Blautia	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
PKFBPKFJ_00635	1121115.AXVN01000008_gene2715	1.33e-275	754.0	COG0738@1|root,COG0738@2|Bacteria,1TQPE@1239|Firmicutes,24AF8@186801|Clostridia,3XYNH@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
PKFBPKFJ_00636	1121115.AXVN01000008_gene2716	2.91e-179	499.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,3XZ1N@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
PKFBPKFJ_00637	1121115.AXVN01000008_gene2717	1.05e-36	124.0	2FAZC@1|root,34364@2|Bacteria,1VXA9@1239|Firmicutes,252GU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00638	457412.RSAG_02580	6.84e-156	438.0	COG2364@1|root,COG2364@2|Bacteria,1US08@1239|Firmicutes,24DPK@186801|Clostridia,3WIPK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00639	1121115.AXVN01000008_gene2719	0.0	925.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3XZ4X@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
PKFBPKFJ_00640	1121115.AXVN01000008_gene2720	9.84e-128	362.0	28PZ1@1|root,2ZCII@2|Bacteria,1V2GX@1239|Firmicutes,24IE1@186801|Clostridia,3Y0MC@572511|Blautia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3877
PKFBPKFJ_00641	457412.RSAG_02584	0.0	1073.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3WGN6@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
PKFBPKFJ_00642	457412.RSAG_02585	0.0	1659.0	COG3957@1|root,COG3957@2|Bacteria,1TR23@1239|Firmicutes,24B8I@186801|Clostridia,3WI73@541000|Ruminococcaceae	186801|Clostridia	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	xfp	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
PKFBPKFJ_00643	457412.RSAG_02586	3.61e-212	586.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3WI8A@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_00644	1121115.AXVN01000157_gene539	0.0	1167.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3XZ6T@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
PKFBPKFJ_00645	457412.RSAG_02588	1.5e-83	247.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PKFBPKFJ_00646	1121115.AXVN01000119_gene3271	0.0	1934.0	COG1061@1|root,COG4951@1|root,COG1061@2|Bacteria,COG4951@2|Bacteria,1TS5R@1239|Firmicutes,24AWW@186801|Clostridia	186801|Clostridia	L	Type III restriction protein res subunit	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,PLDc_2,ResIII
PKFBPKFJ_00647	457412.RSAG_02610	6.23e-35	119.0	2BJ3C@1|root,32DC9@2|Bacteria,1V88B@1239|Firmicutes,24K97@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00648	411461.DORFOR_03054	6.04e-35	126.0	COG4823@1|root,COG4823@2|Bacteria,1V4ZD@1239|Firmicutes,24IEC@186801|Clostridia,27VHG@189330|Dorea	186801|Clostridia	V	COG COG4823 Abortive infection bacteriophage resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
PKFBPKFJ_00649	411469.EUBHAL_02136	6.67e-157	444.0	COG4823@1|root,COG4823@2|Bacteria,1UY67@1239|Firmicutes,24CBG@186801|Clostridia,25X3C@186806|Eubacteriaceae	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
PKFBPKFJ_00650	457412.RSAG_01805	6.43e-189	523.0	COG1246@1|root,COG1246@2|Bacteria,1TRN6@1239|Firmicutes,2484V@186801|Clostridia,3WGHV@541000|Ruminococcaceae	186801|Clostridia	E	YoaP-like	yoaP	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
PKFBPKFJ_00651	457412.RSAG_01806	4.04e-155	434.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,3WGC2@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
PKFBPKFJ_00652	457412.RSAG_01807	5.85e-225	619.0	COG2378@1|root,COG2378@2|Bacteria,1TT23@1239|Firmicutes,248A8@186801|Clostridia,3WGY7@541000|Ruminococcaceae	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
PKFBPKFJ_00653	457412.RSAG_01809	8.28e-178	496.0	COG3843@1|root,COG3843@2|Bacteria,1TR9B@1239|Firmicutes,24A36@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PKFBPKFJ_00654	1121115.AXVN01000095_gene459	4.46e-184	512.0	COG4942@1|root,COG4942@2|Bacteria,1V67C@1239|Firmicutes,25FCI@186801|Clostridia,3Y1NA@572511|Blautia	186801|Clostridia	D	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
PKFBPKFJ_00655	457412.RSAG_01811	6e-28	102.0	2C9RV@1|root,32TYA@2|Bacteria,1VDD3@1239|Firmicutes,24T6T@186801|Clostridia,3WR16@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00656	411463.EUBVEN_00921	3.11e-15	67.8	2E3ZC@1|root,32YWA@2|Bacteria,1VHZW@1239|Firmicutes,24SMN@186801|Clostridia,25XQP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00657	411469.EUBHAL_02118	1.03e-206	572.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,25VEQ@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_00658	457412.RSAG_01813	1.76e-153	431.0	2B7SS@1|root,320Z4@2|Bacteria,1V805@1239|Firmicutes,24IU3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00659	585394.RHOM_13340	3.95e-251	689.0	COG1277@1|root,COG1277@2|Bacteria,1UYRU@1239|Firmicutes,24A07@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
PKFBPKFJ_00660	457412.RSAG_01815	3.98e-276	756.0	COG0642@1|root,COG2770@1|root,COG2205@2|Bacteria,COG2770@2|Bacteria,1TRZX@1239|Firmicutes,249AI@186801|Clostridia,3WIVN@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
PKFBPKFJ_00661	457412.RSAG_01816	1.9e-160	449.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,3WJ1E@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_00662	457412.RSAG_01817	4.98e-52	163.0	2DB8G@1|root,2Z7RT@2|Bacteria,1US26@1239|Firmicutes,24B9G@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
PKFBPKFJ_00663	457412.RSAG_01818	2.26e-110	318.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PKFBPKFJ_00664	457412.RSAG_01819	7.21e-81	240.0	COG4219@1|root,COG4219@2|Bacteria,1V1YX@1239|Firmicutes,24FVT@186801|Clostridia	186801|Clostridia	KT	Domain of unknown function (DUF4825)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4825
PKFBPKFJ_00665	457412.RSAG_01820	2.29e-76	229.0	28NY7@1|root,2ZBVG@2|Bacteria,1V2J3@1239|Firmicutes,24G35@186801|Clostridia,3WJI7@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2992
PKFBPKFJ_00666	457412.RSAG_01821	2.35e-209	578.0	28RA4@1|root,2ZDPR@2|Bacteria,1VC0M@1239|Firmicutes,24GBY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00668	457412.RSAG_01823	1.11e-77	231.0	2C5R4@1|root,30S72@2|Bacteria,1V578@1239|Firmicutes,24IJT@186801|Clostridia,3WKIR@541000|Ruminococcaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PKFBPKFJ_00669	457412.RSAG_01824	0.0	1090.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WGD4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
PKFBPKFJ_00670	1121115.AXVN01000080_gene890	1.97e-228	629.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia,3XZA2@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
PKFBPKFJ_00671	457412.RSAG_01826	1.04e-288	790.0	COG0265@1|root,COG0265@2|Bacteria,1TTAZ@1239|Firmicutes,24BWH@186801|Clostridia,3WJ2P@541000|Ruminococcaceae	186801|Clostridia	O	Trypsin-like peptidase domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
PKFBPKFJ_00673	1121115.AXVN01000052_gene887	0.0	1438.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,3XYKH@572511|Blautia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
PKFBPKFJ_00674	1121115.AXVN01000052_gene886	6.64e-170	474.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3XZ5B@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_00675	1121115.AXVN01000052_gene885	0.0	917.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZ8I@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PKFBPKFJ_00676	457412.RSAG_01830	0.0	1140.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,3WGIC@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
PKFBPKFJ_00677	457412.RSAG_01831	0.0	1352.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia,3WGYT@541000|Ruminococcaceae	186801|Clostridia	S	MCRA family	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
PKFBPKFJ_00678	1121115.AXVN01000052_gene882	2.19e-135	383.0	COG1309@1|root,COG1309@2|Bacteria,1UYIP@1239|Firmicutes,249K5@186801|Clostridia,3XZUQ@572511|Blautia	186801|Clostridia	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
PKFBPKFJ_00679	1121115.AXVN01000052_gene881	7.91e-120	342.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,3XYZI@572511|Blautia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
PKFBPKFJ_00680	1121115.AXVN01000052_gene880	8.46e-133	377.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,3XZIN@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
PKFBPKFJ_00681	1121115.AXVN01000052_gene879	2.09e-10	55.5	28U02@1|root,2ZG6F@2|Bacteria,1W5KD@1239|Firmicutes,2551S@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00682	1121115.AXVN01000052_gene878	0.0	1129.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3XZA6@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
PKFBPKFJ_00683	1121115.AXVN01000052_gene877	2.71e-66	201.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3Y0HD@572511|Blautia	186801|Clostridia	O	Thioredoxin-like domain	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
PKFBPKFJ_00684	457412.RSAG_01838	4.71e-209	578.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3WIBR@541000|Ruminococcaceae	186801|Clostridia	C	pyridine	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
PKFBPKFJ_00685	1121115.AXVN01000052_gene875	7.29e-44	153.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3XYZQ@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
PKFBPKFJ_00686	457412.RSAG_01840	1.92e-242	667.0	2BP77@1|root,32HYI@2|Bacteria,1V84J@1239|Firmicutes,24JDS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00687	457412.RSAG_01841	0.0	1416.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3WGZR@541000|Ruminococcaceae	186801|Clostridia	G	Hydrolase Family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PKFBPKFJ_00688	457412.RSAG_01842	0.0	999.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TRXY@1239|Firmicutes,24BYW@186801|Clostridia,3WN9A@541000|Ruminococcaceae	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
PKFBPKFJ_00689	457412.RSAG_01843	0.0	1062.0	COG2972@1|root,COG2972@2|Bacteria,1UYIY@1239|Firmicutes,24ACA@186801|Clostridia,3WI7T@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,dCache_1
PKFBPKFJ_00690	457412.RSAG_01844	2.91e-193	537.0	COG0395@1|root,COG0395@2|Bacteria,1TRD1@1239|Firmicutes,24BQQ@186801|Clostridia,3WNYS@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PKFBPKFJ_00691	457412.RSAG_01845	1.71e-210	582.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WJ61@541000|Ruminococcaceae	186801|Clostridia	P	transport systems	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PKFBPKFJ_00692	457412.RSAG_01846	0.0	882.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24C14@186801|Clostridia,3WHJ4@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
PKFBPKFJ_00693	1121115.AXVN01000052_gene867	8.28e-295	803.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,3XZHU@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
PKFBPKFJ_00695	457412.RSAG_01848	9.73e-317	861.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3WH4H@541000|Ruminococcaceae	186801|Clostridia	E	O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
PKFBPKFJ_00696	1121115.AXVN01000177_gene3485	6.02e-269	736.0	COG3584@1|root,COG3584@2|Bacteria,1UVF9@1239|Firmicutes,25AFQ@186801|Clostridia,3XZV0@572511|Blautia	186801|Clostridia	S	3D domain	-	-	-	-	-	-	-	-	-	-	-	-	3D
PKFBPKFJ_00697	1121115.AXVN01000047_gene1270	6.35e-48	153.0	2EVPB@1|root,33P3A@2|Bacteria,1VN4M@1239|Firmicutes,24TZY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00699	1121115.AXVN01000047_gene1269	1.13e-292	798.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3XYNE@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
PKFBPKFJ_00700	1121115.AXVN01000047_gene1268	4e-173	482.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3XZ1G@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
PKFBPKFJ_00701	457412.RSAG_01854	2.54e-180	504.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia,3WIZ0@541000|Ruminococcaceae	186801|Clostridia	M	Ami_2	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
PKFBPKFJ_00702	1121115.AXVN01000047_gene1266	0.0	932.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
PKFBPKFJ_00703	1121115.AXVN01000047_gene1265	5.98e-111	319.0	2E823@1|root,332G5@2|Bacteria,1V8A8@1239|Firmicutes,24NHT@186801|Clostridia,3Y088@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00704	1121115.AXVN01000047_gene1264	0.0	983.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
PKFBPKFJ_00705	1121115.AXVN01000047_gene1263	7.18e-57	177.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3Y05R@572511|Blautia	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
PKFBPKFJ_00706	1121115.AXVN01000047_gene1262	1.67e-177	495.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,2480R@186801|Clostridia,3XYZ9@572511|Blautia	186801|Clostridia	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	-	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
PKFBPKFJ_00707	457412.RSAG_01860	0.0	1331.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,3WGDZ@541000|Ruminococcaceae	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
PKFBPKFJ_00708	1121115.AXVN01000047_gene1260	6.55e-222	611.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,3XYUB@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
PKFBPKFJ_00709	457412.RSAG_01862	0.0	1003.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,3WH36@541000|Ruminococcaceae	186801|Clostridia	O	chelatase subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
PKFBPKFJ_00710	1121115.AXVN01000047_gene1258	1.52e-43	141.0	COG1396@1|root,COG1396@2|Bacteria,1UHV9@1239|Firmicutes,25E41@186801|Clostridia,3Y0RB@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PKFBPKFJ_00711	1121115.AXVN01000047_gene1257	4.91e-94	279.0	COG1033@1|root,COG1033@2|Bacteria,1VTBG@1239|Firmicutes,24YPV@186801|Clostridia,3Y1R8@572511|Blautia	186801|Clostridia	S	growth of symbiont in host cell	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00712	1121115.AXVN01000047_gene1256	0.0	964.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3XYNA@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purF_1	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
PKFBPKFJ_00714	457412.RSAG_01867	0.0	1318.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,3WGTB@541000|Ruminococcaceae	186801|Clostridia	G	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
PKFBPKFJ_00715	457412.RSAG_01868	0.0	2953.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,3WGJN@541000|Ruminococcaceae	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
PKFBPKFJ_00716	1121115.AXVN01000047_gene1253	6.51e-247	678.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3XYGT@572511|Blautia	186801|Clostridia	H	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
PKFBPKFJ_00717	457412.RSAG_01870	4.26e-253	696.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3WHIS@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the TelA family	-	-	-	-	-	-	-	-	-	-	-	-	TelA
PKFBPKFJ_00718	1121115.AXVN01000047_gene1251	2.81e-260	719.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,3XZ35@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
PKFBPKFJ_00719	1121115.AXVN01000047_gene1250	6.59e-256	700.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3XZFI@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
PKFBPKFJ_00720	457412.RSAG_01873	1.95e-114	328.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,24FTH@186801|Clostridia,3WJ8H@541000|Ruminococcaceae	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
PKFBPKFJ_00721	457412.RSAG_01874	8.89e-213	586.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,249QG@186801|Clostridia,3WHH9@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
PKFBPKFJ_00722	457412.RSAG_00902	6.43e-284	775.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
PKFBPKFJ_00723	457412.RSAG_00903	1.1e-152	429.0	COG2452@1|root,COG2452@2|Bacteria,1TQNJ@1239|Firmicutes,24B79@186801|Clostridia	186801|Clostridia	L	protein MJ0014 - Methanococcus jannaschii gi 1590824 gb AAB97992.1 (U67460) conserved	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	MerR,MerR_1,Resolvase
PKFBPKFJ_00724	457412.RSAG_00904	0.0	893.0	COG5279@1|root,COG5279@2|Bacteria,1V2RG@1239|Firmicutes,24GD8@186801|Clostridia	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PKFBPKFJ_00726	457412.RSAG_02160	2.89e-100	290.0	COG4824@1|root,COG4824@2|Bacteria,1V934@1239|Firmicutes,24MXR@186801|Clostridia,3WRW2@541000|Ruminococcaceae	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
PKFBPKFJ_00727	457412.RSAG_02159	6.15e-185	513.0	COG5632@1|root,COG5632@2|Bacteria	2|Bacteria	M	N-Acetylmuramoyl-L-alanine amidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PG_binding_1,SPOR
PKFBPKFJ_00728	1121115.AXVN01000022_gene1756	0.0	946.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XYXC@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
PKFBPKFJ_00729	457412.RSAG_02157	2.53e-214	593.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia,3WJJR@541000|Ruminococcaceae	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
PKFBPKFJ_00730	457412.RSAG_02156	0.0	1488.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WH2S@541000|Ruminococcaceae	186801|Clostridia	S	DNA internalization-related competence protein ComEC Rec2	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
PKFBPKFJ_00731	1121115.AXVN01000022_gene1753	0.0	865.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,3XZEH@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 9.36	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
PKFBPKFJ_00732	1121115.AXVN01000022_gene1752	7.72e-194	538.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,3XZ2V@572511|Blautia	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
PKFBPKFJ_00733	457412.RSAG_02153	5.84e-123	351.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,3WJC2@541000|Ruminococcaceae	186801|Clostridia	S	3H domain	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
PKFBPKFJ_00734	457412.RSAG_02152	4.81e-224	617.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3WGEP@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
PKFBPKFJ_00735	1121115.AXVN01000022_gene1749	3.27e-229	632.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,3XZ4T@572511|Blautia	186801|Clostridia	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
PKFBPKFJ_00736	457412.RSAG_02150	6.44e-18	78.2	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3WKKU@541000|Ruminococcaceae	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
PKFBPKFJ_00737	1121115.AXVN01000022_gene1747	1.64e-210	582.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,3XYQQ@572511|Blautia	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
PKFBPKFJ_00738	1121115.AXVN01000022_gene1746	7.93e-271	746.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,3XZD8@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
PKFBPKFJ_00739	1121115.AXVN01000022_gene1745	0.0	1183.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3XYYN@572511|Blautia	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
PKFBPKFJ_00740	1121115.AXVN01000022_gene1744	5.58e-49	158.0	2CAIE@1|root,33XMU@2|Bacteria,1VVJ5@1239|Firmicutes,2511G@186801|Clostridia,3Y25M@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00741	457412.RSAG_02145	2.93e-281	768.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,3WGN4@541000|Ruminococcaceae	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
PKFBPKFJ_00742	1121115.AXVN01000022_gene1742	0.0	1869.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3XYNU@572511|Blautia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
PKFBPKFJ_00743	1121115.AXVN01000022_gene1741	1.32e-224	620.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,3XZC7@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
PKFBPKFJ_00744	1121115.AXVN01000022_gene1740	0.0	1460.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3XYVD@572511|Blautia	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
PKFBPKFJ_00745	1121115.AXVN01000022_gene1739	6.14e-176	489.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,3Y06Y@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
PKFBPKFJ_00746	1121115.AXVN01000022_gene1738	7.07e-92	269.0	2DIZ6@1|root,32UC0@2|Bacteria,1VGDB@1239|Firmicutes,24SFK@186801|Clostridia,3Y0CW@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00747	1121115.AXVN01000022_gene1737	8.88e-248	682.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia,3XZ3Y@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00748	457412.RSAG_02135	5.63e-198	550.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,3WGY9@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
PKFBPKFJ_00749	1121115.AXVN01000022_gene1735	1.78e-301	824.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,24IXJ@186801|Clostridia,3Y2B7@572511|Blautia	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
PKFBPKFJ_00750	1121115.AXVN01000022_gene1734	4.33e-57	177.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia,3Y0CN@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
PKFBPKFJ_00751	457412.RSAG_02132	0.0	1659.0	COG1376@1|root,COG5263@1|root,COG1376@2|Bacteria,COG5263@2|Bacteria,1V0DN@1239|Firmicutes,24BCJ@186801|Clostridia,3WGYS@541000|Ruminococcaceae	186801|Clostridia	D	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,YkuD
PKFBPKFJ_00752	1121115.AXVN01000022_gene1732	0.0	976.0	COG3757@1|root,COG5263@1|root,COG3757@2|Bacteria,COG5263@2|Bacteria,1TPVT@1239|Firmicutes,24DEH@186801|Clostridia,3Y010@572511|Blautia	186801|Clostridia	M	Glycosyl hydrolases family 25	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Glyco_hydro_25
PKFBPKFJ_00753	457412.RSAG_02130	4.97e-70	211.0	COG2076@1|root,COG2076@2|Bacteria,1VFDI@1239|Firmicutes,24S4I@186801|Clostridia,3WKQ8@541000|Ruminococcaceae	186801|Clostridia	P	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PKFBPKFJ_00754	1121115.AXVN01000022_gene1730	1.84e-76	228.0	COG0697@1|root,COG0697@2|Bacteria,1UHS0@1239|Firmicutes,25FFB@186801|Clostridia,3Y0C7@572511|Blautia	186801|Clostridia	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PKFBPKFJ_00755	1121115.AXVN01000022_gene1729	3.35e-218	602.0	COG0463@1|root,COG0463@2|Bacteria,1TRFA@1239|Firmicutes,249CR@186801|Clostridia,3XZM2@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
PKFBPKFJ_00756	1121115.AXVN01000022_gene1728	5.3e-240	658.0	COG0399@1|root,COG0399@2|Bacteria,1TZB6@1239|Firmicutes,249QE@186801|Clostridia,3Y0S8@572511|Blautia	186801|Clostridia	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00757	1121115.AXVN01000022_gene1727	0.0	875.0	COG0027@1|root,COG0027@2|Bacteria,1VR1C@1239|Firmicutes,25M0G@186801|Clostridia,3XZT7@572511|Blautia	186801|Clostridia	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
PKFBPKFJ_00758	1121115.AXVN01000022_gene1726	2.91e-283	773.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,3XZ4N@572511|Blautia	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
PKFBPKFJ_00759	1121115.AXVN01000022_gene1725	1.57e-291	798.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3XZCB@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
PKFBPKFJ_00760	1121115.AXVN01000022_gene1724	1.89e-138	390.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,3XYH7@572511|Blautia	186801|Clostridia	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
PKFBPKFJ_00761	457412.RSAG_02122	1.45e-192	534.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,248R0@186801|Clostridia,3WKBW@541000|Ruminococcaceae	186801|Clostridia	GM	ABC-2 type transporter	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
PKFBPKFJ_00762	1121115.AXVN01000072_gene3917	3.01e-311	847.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3XYUG@572511|Blautia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score 9.49	-	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
PKFBPKFJ_00763	1121115.AXVN01000072_gene3916	0.0	1463.0	COG2242@1|root,COG2242@2|Bacteria,1TPEE@1239|Firmicutes,24D9B@186801|Clostridia,3XZAT@572511|Blautia	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
PKFBPKFJ_00764	1121115.AXVN01000072_gene3915	0.0	1656.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1VRQS@1239|Firmicutes,24XRU@186801|Clostridia,3XYHN@572511|Blautia	186801|Clostridia	M	Glycosyltransferase like family	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PKFBPKFJ_00765	457412.RSAG_02118	0.0	1638.0	COG1216@1|root,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3WHZS@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
PKFBPKFJ_00766	457412.RSAG_02117	0.0	988.0	COG1807@1|root,COG1807@2|Bacteria,1V22V@1239|Firmicutes,24GKH@186801|Clostridia,3WK06@541000|Ruminococcaceae	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT,PMT_2
PKFBPKFJ_00767	1121115.AXVN01000072_gene3912	5.33e-290	795.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3XZGM@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
PKFBPKFJ_00768	1121115.AXVN01000072_gene3911	0.0	1298.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3XYRF@572511|Blautia	186801|Clostridia	M	Glycosyltransferase like family	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
PKFBPKFJ_00769	1121115.AXVN01000072_gene3910	1.85e-239	657.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia,3XYQG@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
PKFBPKFJ_00770	457412.RSAG_02113	0.0	909.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,3WRHZ@541000|Ruminococcaceae	186801|Clostridia	M	CoA-binding domain	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
PKFBPKFJ_00771	457412.RSAG_02112	5.49e-272	752.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,3WGW9@541000|Ruminococcaceae	186801|Clostridia	K	Cell envelope-like function transcriptional attenuator common domain protein	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
PKFBPKFJ_00772	1121115.AXVN01000072_gene3907	5.28e-237	650.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia,3XZN2@572511|Blautia	186801|Clostridia	S	LPS side chain defect rhamnosyl transferase	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
PKFBPKFJ_00773	457412.RSAG_02110	0.0	875.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3WH0E@541000|Ruminococcaceae	186801|Clostridia	O	Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
PKFBPKFJ_00774	1121115.AXVN01000063_gene700	0.0	907.0	COG1219@1|root,COG1219@2|Bacteria,1TPDI@1239|Firmicutes,24AEG@186801|Clostridia,3XYQ7@572511|Blautia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX_1	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
PKFBPKFJ_00775	1121115.AXVN01000063_gene701	9.64e-101	296.0	2DR5I@1|root,33A9E@2|Bacteria,1VM5P@1239|Firmicutes,24JQJ@186801|Clostridia,3Y0KF@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	zinc_ribbon_2
PKFBPKFJ_00776	1121115.AXVN01000063_gene702	2.66e-311	854.0	COG4886@1|root,COG5492@1|root,COG4886@2|Bacteria,COG5492@2|Bacteria,1VRK1@1239|Firmicutes,25KN7@186801|Clostridia,3Y1XU@572511|Blautia	186801|Clostridia	N	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00777	457412.RSAG_02106	1.6e-271	743.0	COG4733@1|root,COG4733@2|Bacteria,1VDWT@1239|Firmicutes,24ZKB@186801|Clostridia,3WMCI@541000|Ruminococcaceae	186801|Clostridia	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	fn3
PKFBPKFJ_00779	1121115.AXVN01000063_gene704	7.86e-268	732.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3XYS9@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
PKFBPKFJ_00780	457412.RSAG_02104	0.0	2086.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3WG9X@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
PKFBPKFJ_00781	457412.RSAG_02103	2.16e-239	658.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WGRJ@541000|Ruminococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
PKFBPKFJ_00782	457412.RSAG_02102	4.05e-215	595.0	COG1910@1|root,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,3WHAS@541000|Ruminococcaceae	186801|Clostridia	P	TIGRFAM DNA binding domain	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_17,PBP_like
PKFBPKFJ_00783	1121115.AXVN01000063_gene708	2.67e-39	130.0	COG3585@1|root,COG3585@2|Bacteria,1VEPR@1239|Firmicutes,24QTI@186801|Clostridia	186801|Clostridia	H	pfam tobe	mopI	-	-	ko:K02019	-	-	-	-	ko00000,ko03000	-	-	-	TOBE
PKFBPKFJ_00784	1121115.AXVN01000063_gene709	7.75e-186	520.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,3Y07V@572511|Blautia	186801|Clostridia	P	COG COG0725 ABC-type molybdate transport system, periplasmic component	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
PKFBPKFJ_00785	1121115.AXVN01000063_gene710	2.03e-154	434.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,3XZF3@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
PKFBPKFJ_00786	457412.RSAG_04588	1.84e-263	720.0	COG3842@1|root,COG3842@2|Bacteria,1TQ18@1239|Firmicutes,24AEK@186801|Clostridia,3WGIR@541000|Ruminococcaceae	186801|Clostridia	E	ABC transporter	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
PKFBPKFJ_00787	1121115.AXVN01000063_gene712	1.83e-259	711.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,25N06@186801|Clostridia,3XYXQ@572511|Blautia	186801|Clostridia	KT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
PKFBPKFJ_00788	1121115.AXVN01000063_gene713	9.56e-266	728.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XYK4@572511|Blautia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
PKFBPKFJ_00789	1121115.AXVN01000063_gene714	1.07e-239	659.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia,3XYQP@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
PKFBPKFJ_00790	457412.RSAG_02095	3.02e-44	143.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,3WKZF@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
PKFBPKFJ_00791	1121115.AXVN01000063_gene716	1.11e-106	307.0	2DZF8@1|root,32V97@2|Bacteria,1VK00@1239|Firmicutes,24NVD@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00792	457412.RSAG_02093	6.35e-228	627.0	COG4823@1|root,COG4823@2|Bacteria,1V4ZD@1239|Firmicutes,24BWK@186801|Clostridia,3WRSH@541000|Ruminococcaceae	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
PKFBPKFJ_00793	1121115.AXVN01000063_gene717	5.47e-103	298.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,25KA6@186801|Clostridia,3Y1KT@572511|Blautia	186801|Clostridia	P	COG COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
PKFBPKFJ_00794	1121115.AXVN01000109_gene2345	0.0	1004.0	COG3039@1|root,COG3039@2|Bacteria,1U377@1239|Firmicutes,24ASA@186801|Clostridia,3Y1AH@572511|Blautia	186801|Clostridia	L	COG NOG25267 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
PKFBPKFJ_00796	397288.C806_04401	1.25e-131	379.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	GerE,Response_reg,TauD
PKFBPKFJ_00797	411470.RUMGNA_01413	8.41e-280	765.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3Y1BX@572511|Blautia	186801|Clostridia	H	S-adenosylmethionine synthetase, C-terminal domain	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
PKFBPKFJ_00798	397288.C806_04403	1.88e-229	633.0	COG0596@1|root,COG0596@2|Bacteria,1UZ83@1239|Firmicutes,25F3U@186801|Clostridia	186801|Clostridia	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
PKFBPKFJ_00799	1121115.AXVN01000033_gene2903	4.95e-89	261.0	COG0745@1|root,COG0745@2|Bacteria,1W56V@1239|Firmicutes,25M0R@186801|Clostridia,3Y1KC@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
PKFBPKFJ_00800	1121115.AXVN01000033_gene2902	1.56e-147	416.0	COG1961@1|root,COG1961@2|Bacteria,1UZM8@1239|Firmicutes,248B3@186801|Clostridia,3Y0JM@572511|Blautia	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Resolvase
PKFBPKFJ_00801	397288.C806_04406	4.08e-51	160.0	2CDC9@1|root,32RXG@2|Bacteria,1VA39@1239|Firmicutes,24MYY@186801|Clostridia,27SAC@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF5348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
PKFBPKFJ_00802	397288.C806_04407	8.55e-64	194.0	2ESAM@1|root,33JVB@2|Bacteria,1VKW5@1239|Firmicutes,24WIQ@186801|Clostridia,27SPV@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00803	742765.HMPREF9457_02363	3.09e-149	421.0	2DC5M@1|root,2ZCZR@2|Bacteria,1W335@1239|Firmicutes,254QK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00805	1121115.AXVN01000033_gene2898	3.93e-290	792.0	2BEY5@1|root,328PU@2|Bacteria,1UUMX@1239|Firmicutes,2576R@186801|Clostridia	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
PKFBPKFJ_00806	1121115.AXVN01000033_gene2897	1.48e-146	412.0	COG4186@1|root,COG4186@2|Bacteria,1V40P@1239|Firmicutes,24D6T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
PKFBPKFJ_00807	1121115.AXVN01000033_gene2896	1.06e-184	512.0	COG0727@1|root,COG0727@2|Bacteria,1V0FA@1239|Firmicutes,24CDU@186801|Clostridia,3XZY0@572511|Blautia	186801|Clostridia	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
PKFBPKFJ_00808	1121115.AXVN01000033_gene2895	1.92e-190	527.0	2DHPC@1|root,300GV@2|Bacteria,1UQ0M@1239|Firmicutes,257NA@186801|Clostridia,3Y21S@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00809	1121115.AXVN01000033_gene2894	0.0	893.0	COG1373@1|root,COG1373@2|Bacteria,1UZD0@1239|Firmicutes,25EI0@186801|Clostridia,3XZT6@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
PKFBPKFJ_00810	1121115.AXVN01000033_gene2893	2.07e-111	319.0	COG5113@1|root,COG3236@2|Bacteria,1V7IA@1239|Firmicutes,2595B@186801|Clostridia,3XZSR@572511|Blautia	186801|Clostridia	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
PKFBPKFJ_00811	742765.HMPREF9457_02367	1.25e-51	162.0	2E7JW@1|root,33220@2|Bacteria,1VFQV@1239|Firmicutes,24WME@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00812	1121115.AXVN01000033_gene2890	4.88e-96	279.0	2BCGU@1|root,3262M@2|Bacteria,1US1T@1239|Firmicutes,25A04@186801|Clostridia,3XYXS@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00813	742765.HMPREF9457_02370	0.0	1346.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
PKFBPKFJ_00814	742765.HMPREF9457_02373	4.27e-98	287.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia,27X3H@189330|Dorea	186801|Clostridia	E	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
PKFBPKFJ_00815	411470.RUMGNA_01432	2.03e-125	357.0	2A951@1|root,30Y9F@2|Bacteria,1V5FW@1239|Firmicutes,24J39@186801|Clostridia,3XYJV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00816	411470.RUMGNA_01433	3.9e-50	159.0	2BYMH@1|root,30FPR@2|Bacteria,1UECX@1239|Firmicutes,25J8W@186801|Clostridia,3Y1SS@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00817	742765.HMPREF9457_02377	4.01e-262	717.0	COG2189@1|root,COG2189@2|Bacteria,1UK7A@1239|Firmicutes,25FP0@186801|Clostridia	186801|Clostridia	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00818	411470.RUMGNA_01435	4.46e-127	361.0	2EERV@1|root,30FD8@2|Bacteria,1UDVT@1239|Firmicutes,25IPJ@186801|Clostridia,3Y0XH@572511|Blautia	186801|Clostridia	K	MraZ protein, putative antitoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	MraZ
PKFBPKFJ_00819	411470.RUMGNA_01436	1.63e-177	494.0	28MBF@1|root,2ZAPY@2|Bacteria,1UZPT@1239|Firmicutes,24DCB@186801|Clostridia,3XYYA@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00820	411470.RUMGNA_01437	0.0	1388.0	COG4548@1|root,COG4548@2|Bacteria,1TPW1@1239|Firmicutes,24ASV@186801|Clostridia,3XYZT@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
PKFBPKFJ_00821	1121115.AXVN01000082_gene2997	0.0	1211.0	COG0714@1|root,COG0714@2|Bacteria,1UZ11@1239|Firmicutes,249DK@186801|Clostridia,3XYWA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
PKFBPKFJ_00822	411470.RUMGNA_01440	3.41e-186	517.0	2CKKE@1|root,2ZC1Q@2|Bacteria,1V2EX@1239|Firmicutes,24DCS@186801|Clostridia,3XYRZ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00823	411470.RUMGNA_01441	3.42e-149	420.0	2BXGH@1|root,32R1A@2|Bacteria,1V8FX@1239|Firmicutes,24JT8@186801|Clostridia,3XZCC@572511|Blautia	186801|Clostridia	L	Single-strand binding protein family	-	-	-	-	-	-	-	-	-	-	-	-	SSB
PKFBPKFJ_00824	1121115.AXVN01000082_gene3000	1.62e-35	122.0	2FA0G@1|root,3429J@2|Bacteria,1VXK8@1239|Firmicutes,24RRN@186801|Clostridia,3Y0WK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00825	537007.BLAHAN_06989	1.27e-158	445.0	COG0745@1|root,COG0745@2|Bacteria,1TT2Z@1239|Firmicutes,248PN@186801|Clostridia,3Y028@572511|Blautia	186801|Clostridia	T	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_00826	1121115.AXVN01000082_gene3001	8.58e-220	606.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,3XZPY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_00827	537007.BLAHAN_06987	2.21e-186	518.0	2DUYM@1|root,33T23@2|Bacteria,1VSXR@1239|Firmicutes,24Y99@186801|Clostridia,3XZVU@572511|Blautia	186801|Clostridia	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
PKFBPKFJ_00829	537007.BLAHAN_06986	4.78e-312	848.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,24A6D@186801|Clostridia,3Y0GZ@572511|Blautia	186801|Clostridia	C	Radical SAM domain protein	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
PKFBPKFJ_00830	537007.BLAHAN_06985	0.0	982.0	COG1132@1|root,COG1132@2|Bacteria,1UYYQ@1239|Firmicutes,24BTI@186801|Clostridia,3Y10E@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
PKFBPKFJ_00831	537007.BLAHAN_06984	5.94e-194	539.0	COG0642@1|root,COG2205@2|Bacteria,1VU79@1239|Firmicutes,24XMA@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_00832	1121115.AXVN01000070_gene3931	2.27e-98	286.0	2E8K8@1|root,30GFW@2|Bacteria,1UFYP@1239|Firmicutes,25PXS@186801|Clostridia,3Y1HD@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00833	1121115.AXVN01000070_gene3930	1.06e-159	447.0	28J1V@1|root,2Z8YN@2|Bacteria,1UZQA@1239|Firmicutes,24CAR@186801|Clostridia,3XZNW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00834	1121115.AXVN01000070_gene3929	7.65e-136	384.0	2BYWM@1|root,32R3Z@2|Bacteria,1V92X@1239|Firmicutes,24K3P@186801|Clostridia,3XZEJ@572511|Blautia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
PKFBPKFJ_00835	1121115.AXVN01000070_gene3928	3.19e-100	290.0	2C7AV@1|root,32S15@2|Bacteria,1V5N7@1239|Firmicutes,24HXV@186801|Clostridia,3XZB0@572511|Blautia	186801|Clostridia	S	zinc-finger-containing domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3268
PKFBPKFJ_00836	1121115.AXVN01000070_gene3927	2.12e-58	180.0	2EAAC@1|root,318UQ@2|Bacteria,1UECF@1239|Firmicutes,25J8C@186801|Clostridia,3Y1VS@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00837	742765.HMPREF9457_02398	2e-103	298.0	2DN7W@1|root,32W0R@2|Bacteria,1VDYD@1239|Firmicutes,24PYD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00838	742765.HMPREF9457_02399	0.0	2578.0	COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia,27UY6@189330|Dorea	186801|Clostridia	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
PKFBPKFJ_00839	411470.RUMGNA_01452	0.0	1875.0	COG3451@1|root,COG3451@2|Bacteria,1TQGE@1239|Firmicutes,24ACY@186801|Clostridia,3XYZ2@572511|Blautia	186801|Clostridia	U	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
PKFBPKFJ_00840	1121115.AXVN01000070_gene3924	3.79e-129	369.0	2CQTU@1|root,32SMS@2|Bacteria,1VE7V@1239|Firmicutes,24PZ5@186801|Clostridia,3XZG9@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF5038)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5038
PKFBPKFJ_00841	411470.RUMGNA_01454	0.0	1146.0	COG0741@1|root,COG4990@1|root,COG0741@2|Bacteria,COG4990@2|Bacteria,1W01C@1239|Firmicutes,25EEX@186801|Clostridia,3XZFS@572511|Blautia	186801|Clostridia	M	Papain-like cysteine protease AvrRpt2	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,Peptidase_C39_2
PKFBPKFJ_00842	742765.HMPREF9457_02403	1.71e-193	540.0	2DBP9@1|root,2ZA85@2|Bacteria,1UXYH@1239|Firmicutes,24B1P@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00843	1121115.AXVN01000070_gene3921	9.01e-165	461.0	28HST@1|root,2Z7ZU@2|Bacteria,1TPCE@1239|Firmicutes,24AG2@186801|Clostridia,3XYYQ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00844	742765.HMPREF9457_02405	4.69e-86	253.0	2AY78@1|root,31Q9C@2|Bacteria,1V75X@1239|Firmicutes,24I58@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00845	411470.RUMGNA_01401	1.5e-26	114.0	COG1404@1|root,COG1404@2|Bacteria,1UVHX@1239|Firmicutes,25KIN@186801|Clostridia,3Y0ST@572511|Blautia	186801|Clostridia	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
PKFBPKFJ_00846	742765.HMPREF9457_03420	6.68e-78	251.0	COG0641@1|root,COG0641@2|Bacteria,1V5ZZ@1239|Firmicutes,24IY0@186801|Clostridia	186801|Clostridia	C	Radical SAM superfamily	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
PKFBPKFJ_00847	397288.C806_04391	9.88e-49	178.0	COG0641@1|root,COG0641@2|Bacteria	2|Bacteria	C	radical SAM	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
PKFBPKFJ_00849	1235798.C817_02750	1.43e-205	608.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia	1239|Firmicutes	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00850	1121115.AXVN01000112_gene2362	5.82e-101	296.0	COG0745@1|root,COG0745@2|Bacteria,1TSCM@1239|Firmicutes,248K7@186801|Clostridia	186801|Clostridia	K	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_00851	1235793.C809_01632	7.17e-90	277.0	COG0642@1|root,COG2205@2|Bacteria,1TXC7@1239|Firmicutes,2492E@186801|Clostridia,27JKW@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_00852	1410653.JHVC01000021_gene1277	4.69e-161	457.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,36DFE@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990,ko:K19309	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC_tran
PKFBPKFJ_00853	272563.CD630_10960	1.6e-90	276.0	COG1668@1|root,COG1668@2|Bacteria,1U5Z3@1239|Firmicutes,24AXX@186801|Clostridia	186801|Clostridia	CP	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992,ko:K19310	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC2_membrane_4
PKFBPKFJ_00854	272563.CD630_10950	3.01e-73	231.0	COG4200@1|root,COG4200@2|Bacteria,1TT70@1239|Firmicutes,24ANA@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
PKFBPKFJ_00856	665950.HMPREF1025_02919	0.0	1009.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,251Y5@186801|Clostridia,27UCA@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
PKFBPKFJ_00857	665950.HMPREF1025_02918	2.36e-77	230.0	COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,24K4W@186801|Clostridia,27P7R@186928|unclassified Lachnospiraceae	186801|Clostridia	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
PKFBPKFJ_00858	665950.HMPREF1025_02917	6.67e-94	274.0	28IAH@1|root,2Z8D3@2|Bacteria,1TRGI@1239|Firmicutes,24U6D@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00859	1385512.N784_11175	8.29e-65	236.0	COG4403@1|root,COG4403@2|Bacteria,1TS6F@1239|Firmicutes,4HCU7@91061|Bacilli	91061|Bacilli	V	Domain of unknown function (DUF4135)	lcnDR2	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
PKFBPKFJ_00860	665950.HMPREF1025_00462	3.48e-288	786.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,27IJX@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase
PKFBPKFJ_00861	1280698.AUJS01000003_gene2655	7.81e-42	137.0	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia,27X06@189330|Dorea	186801|Clostridia	L	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
PKFBPKFJ_00862	1121333.JMLH01000019_gene1519	1.57e-50	160.0	2BVCS@1|root,32QSU@2|Bacteria,1UHK3@1239|Firmicutes	1239|Firmicutes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
PKFBPKFJ_00863	411463.EUBVEN_00782	9.82e-92	268.0	COG1595@1|root,COG1595@2|Bacteria,1V1UU@1239|Firmicutes,24G23@186801|Clostridia,25W9K@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
PKFBPKFJ_00864	411463.EUBVEN_00781	1.34e-154	434.0	COG0745@1|root,COG0745@2|Bacteria,1UYA6@1239|Firmicutes,24J6Y@186801|Clostridia,25ZQS@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_00865	411463.EUBVEN_00780	3.21e-213	589.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,25VDN@186806|Eubacteriaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_00866	411463.EUBVEN_00779	1.47e-177	496.0	28N9U@1|root,2ZBDR@2|Bacteria,1V0XN@1239|Firmicutes,24NJN@186801|Clostridia,25YTA@186806|Eubacteriaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
PKFBPKFJ_00867	411463.EUBVEN_00778	1.14e-195	544.0	COG0642@1|root,COG2205@2|Bacteria,1UZKD@1239|Firmicutes,249N3@186801|Clostridia,25WS9@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_00868	411463.EUBVEN_00777	1.51e-71	216.0	2AJM6@1|root,31A8C@2|Bacteria,1V9V5@1239|Firmicutes,24KJN@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00869	665950.HMPREF1025_00813	5.6e-45	145.0	COG0582@1|root,COG0582@2|Bacteria,1VBGF@1239|Firmicutes,24NRM@186801|Clostridia,27SHV@186928|unclassified Lachnospiraceae	186801|Clostridia	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
PKFBPKFJ_00870	665950.HMPREF1025_00812	1.43e-75	226.0	COG1476@1|root,COG1476@2|Bacteria,1UHV0@1239|Firmicutes,25E3M@186801|Clostridia,27PW2@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_00871	665950.HMPREF1025_00447	1.56e-203	565.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,27KG9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
PKFBPKFJ_00872	411470.RUMGNA_02431	2.64e-243	668.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,3XZR2@572511|Blautia	186801|Clostridia	M	COG COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
PKFBPKFJ_00873	469596.HMPREF9488_00503	0.0	1296.0	COG3064@1|root,COG3064@2|Bacteria,1UIYZ@1239|Firmicutes,3VQ0R@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00874	1121333.JMLH01000011_gene658	0.0	1257.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,3VP95@526524|Erysipelotrichia	526524|Erysipelotrichia	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
PKFBPKFJ_00876	945021.TEH_10620	3.09e-70	222.0	COG3279@1|root,COG3279@2|Bacteria,1UWIY@1239|Firmicutes,4I2MT@91061|Bacilli,4B3ZZ@81852|Enterococcaceae	91061|Bacilli	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_00878	1226325.HMPREF1548_00196	2.96e-240	691.0	COG0641@1|root,COG0641@2|Bacteria,1TRN3@1239|Firmicutes,24BV6@186801|Clostridia,36HNK@31979|Clostridiaceae	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
PKFBPKFJ_00879	1226325.HMPREF1548_00197	3.63e-06	48.5	2A0C6@1|root,30NFP@2|Bacteria,1UUK3@1239|Firmicutes,2570F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00880	525255.HMPREF0077_1418	1.35e-88	291.0	COG1132@1|root,COG1132@2|Bacteria,1UYYQ@1239|Firmicutes,24BTI@186801|Clostridia,22H3K@1570339|Peptoniphilaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PKFBPKFJ_00884	398512.JQKC01000041_gene4132	8.13e-26	99.0	COG0640@1|root,COG0640@2|Bacteria,1VEC2@1239|Firmicutes,24TUU@186801|Clostridia,3WPRN@541000|Ruminococcaceae	186801|Clostridia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34
PKFBPKFJ_00886	411462.DORLON_00511	2.38e-82	254.0	COG1136@1|root,COG1136@2|Bacteria,1UZ9G@1239|Firmicutes,24FMJ@186801|Clostridia,27X9N@189330|Dorea	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PKFBPKFJ_00887	903814.ELI_3067	5.46e-14	72.4	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,25ZNX@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	resD	-	-	ko:K07668,ko:K07775	ko02020,map02020	M00458,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_00890	1449050.JNLE01000003_gene2061	3.9e-189	583.0	COG4403@1|root,COG4403@2|Bacteria,1TS6F@1239|Firmicutes,247JU@186801|Clostridia,36EB8@31979|Clostridiaceae	186801|Clostridia	V	PFAM Lanthionine synthetase C family protein	lanM	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
PKFBPKFJ_00891	701521.PECL_1942	4.13e-161	488.0	COG2274@1|root,COG3271@1|root,COG2274@2|Bacteria,COG3271@2|Bacteria,1V77J@1239|Firmicutes,4HAX2@91061|Bacilli,3F9FP@33958|Lactobacillaceae	91061|Bacilli	V	ATPases associated with a variety of cellular activities	lanT	-	-	ko:K06148,ko:K13409,ko:K20344,ko:K20386	ko02010,ko02024,ko04626,map02010,map02024,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko02000,ko02044	3.A.1,3.A.1.110,3.A.1.111.1,3.A.1.112	-	-	ABC_membrane,ABC_tran,Peptidase_C39
PKFBPKFJ_00892	1235797.C816_03672	1.53e-133	400.0	COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,24AAW@186801|Clostridia,2N857@216572|Oscillospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_00893	1235797.C816_03671	6.19e-112	327.0	COG0745@1|root,COG0745@2|Bacteria,1TYPK@1239|Firmicutes,247Y9@186801|Clostridia,2N8B5@216572|Oscillospiraceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_00894	1122925.KB895378_gene2561	4.25e-157	447.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HAGA@91061|Bacilli,274EC@186822|Paenibacillaceae	91061|Bacilli	V	Bacitracin ABC transporter, ATP-binding protein	potA3	-	-	ko:K01990,ko:K19309	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC_tran
PKFBPKFJ_00895	658086.HMPREF0994_05177	1.12e-143	410.0	COG1668@1|root,COG1668@2|Bacteria,1U5Z3@1239|Firmicutes,24AXX@186801|Clostridia,27KIE@186928|unclassified Lachnospiraceae	186801|Clostridia	CP	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K19310	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC2_membrane_4
PKFBPKFJ_00896	445972.ANACOL_00969	9.55e-114	334.0	COG4200@1|root,COG4200@2|Bacteria,1TT70@1239|Firmicutes,24ANA@186801|Clostridia,3WJ5I@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
PKFBPKFJ_00897	97139.C824_05728	3.5e-55	177.0	28PS7@1|root,2ZCDT@2|Bacteria,1V252@1239|Firmicutes,24GY8@186801|Clostridia,36KU3@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00898	1121115.AXVN01000112_gene2356	1.65e-83	254.0	2E69V@1|root,330XS@2|Bacteria,1VEQ2@1239|Firmicutes,24T5H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00899	411459.RUMOBE_02280	9.51e-62	191.0	COG1396@1|root,COG1396@2|Bacteria,1UK3A@1239|Firmicutes,25FI1@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_00900	742765.HMPREF9457_00819	8.24e-132	378.0	COG3279@1|root,COG3279@2|Bacteria,1V0QJ@1239|Firmicutes,24E66@186801|Clostridia,27WYY@189330|Dorea	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_00901	742765.HMPREF9457_00818	2.33e-173	499.0	COG3290@1|root,COG3290@2|Bacteria,1UWBA@1239|Firmicutes,25KSH@186801|Clostridia,27X42@189330|Dorea	2|Bacteria	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,PAS_9
PKFBPKFJ_00904	411459.RUMOBE_02285	1.59e-73	227.0	COG4512@1|root,COG4512@2|Bacteria,1V8NK@1239|Firmicutes,24KUY@186801|Clostridia	186801|Clostridia	KOT	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AgrB
PKFBPKFJ_00905	632245.CLP_4281	2.24e-11	65.5	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,36EQW@31979|Clostridiaceae	186801|Clostridia	KT	response regulator	srrA1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_00906	1121115.AXVN01000027_gene575	5.08e-136	385.0	28K00@1|root,2Z9Q0@2|Bacteria,1TR6B@1239|Firmicutes,24EVF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00907	1121115.AXVN01000027_gene576	1.2e-147	416.0	2AC6M@1|root,311R8@2|Bacteria,1V46J@1239|Firmicutes,25MQB@186801|Clostridia,3Y144@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00908	1121115.AXVN01000027_gene577	6.73e-31	109.0	2EPXM@1|root,33HI5@2|Bacteria,1VNMZ@1239|Firmicutes,24W4H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00910	411490.ANACAC_02256	3.35e-18	81.6	COG3620@1|root,COG3620@2|Bacteria,1VQR3@1239|Firmicutes,24WBD@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_00911	1121115.AXVN01000027_gene579	2.95e-101	293.0	COG0745@1|root,COG0745@2|Bacteria,1USHD@1239|Firmicutes,25AHJ@186801|Clostridia,3Y0K3@572511|Blautia	186801|Clostridia	KT	Sporulation initiation factor Spo0A C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
PKFBPKFJ_00913	1121115.AXVN01000027_gene581	3.01e-49	157.0	2DMFX@1|root,32R8N@2|Bacteria,1V9I5@1239|Firmicutes,24KI0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00914	1121115.AXVN01000027_gene582	0.0	1076.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYKU@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_00915	1121115.AXVN01000027_gene583	0.0	1088.0	COG1961@1|root,COG1961@2|Bacteria,1TQ8Y@1239|Firmicutes,247WD@186801|Clostridia,3XZ0Q@572511|Blautia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_00916	1121115.AXVN01000027_gene584	0.0	1019.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia,3XZC2@572511|Blautia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_00918	1121115.AXVN01000027_gene586	1e-167	469.0	28VH4@1|root,2ZHJM@2|Bacteria,1W2SJ@1239|Firmicutes,25511@186801|Clostridia,3Y20Y@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00919	1121115.AXVN01000027_gene587	3.38e-106	308.0	COG2105@1|root,COG2105@2|Bacteria,1VGQA@1239|Firmicutes,24N69@186801|Clostridia,3Y0SW@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4314
PKFBPKFJ_00920	1121115.AXVN01000017_gene266	5.5e-113	327.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3Y11K@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_00921	1121115.AXVN01000017_gene265	0.0	1501.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,247QW@186801|Clostridia,3Y19B@572511|Blautia	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PKFBPKFJ_00922	411469.EUBHAL_02190	5.57e-74	223.0	COG3293@1|root,COG3293@2|Bacteria,1V7PZ@1239|Firmicutes,24J9M@186801|Clostridia	186801|Clostridia	L	Putative transposase of IS4/5 family (DUF4096)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4096
PKFBPKFJ_00923	411469.EUBHAL_02189	8.58e-71	213.0	COG3293@1|root,COG3293@2|Bacteria,1V5EV@1239|Firmicutes,24HBB@186801|Clostridia,25YMP@186806|Eubacteriaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
PKFBPKFJ_00924	1121115.AXVN01000017_gene264	5.86e-70	214.0	2BBFY@1|root,324Z7@2|Bacteria,1UR44@1239|Firmicutes,258XU@186801|Clostridia,3Y266@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00925	457412.RSAG_00247	4.52e-316	862.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_00926	1121115.AXVN01000017_gene262	2.7e-127	362.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,3Y0A5@572511|Blautia	186801|Clostridia	I	COG COG0671 Membrane-associated phospholipid phosphatase	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
PKFBPKFJ_00927	1121115.AXVN01000017_gene261	8.98e-278	758.0	COG2006@1|root,COG2006@2|Bacteria,1TRYQ@1239|Firmicutes,24966@186801|Clostridia,3XZNX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
PKFBPKFJ_00928	457412.RSAG_00243	4.22e-136	385.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3WJWK@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
PKFBPKFJ_00929	1121115.AXVN01000017_gene259	5.46e-193	535.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia,3XZ2J@572511|Blautia	186801|Clostridia	C	COG COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
PKFBPKFJ_00930	1121115.AXVN01000017_gene258	1.7e-111	320.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia,3XZVY@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
PKFBPKFJ_00931	1121115.AXVN01000017_gene257	0.0	1610.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3XYHY@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PKFBPKFJ_00932	457412.RSAG_00239	1.43e-252	694.0	29ZQ1@1|root,327GJ@2|Bacteria,1UTCQ@1239|Firmicutes,258AP@186801|Clostridia,3WMBU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00933	1121115.AXVN01000017_gene255	5.09e-203	561.0	2A5RW@1|root,30UGW@2|Bacteria,1US7T@1239|Firmicutes,25A6N@186801|Clostridia,3Y26D@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00934	457412.RSAG_00237	0.0	1010.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,3WGRM@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	mleN_1	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
PKFBPKFJ_00936	457412.RSAG_00236	2.63e-210	582.0	COG3103@1|root,COG4991@2|Bacteria	2|Bacteria	T	sh3 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
PKFBPKFJ_00937	457412.RSAG_00235	3.34e-247	684.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,249SN@186801|Clostridia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,ChW,Polysacc_deac_1
PKFBPKFJ_00938	457412.RSAG_04728	0.0	1268.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3WGTP@541000|Ruminococcaceae	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
PKFBPKFJ_00939	1121115.AXVN01000017_gene249	2.4e-231	635.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3XZIH@572511|Blautia	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
PKFBPKFJ_00940	1121115.AXVN01000017_gene248	4.45e-133	377.0	COG4636@1|root,COG4636@2|Bacteria,1V8DJ@1239|Firmicutes,24G93@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
PKFBPKFJ_00941	457412.RSAG_00230	2.99e-49	156.0	2E45D@1|root,32Z1F@2|Bacteria,1VEXR@1239|Firmicutes,24R89@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00942	457412.RSAG_00229	6.01e-141	397.0	2ESIJ@1|root,33K39@2|Bacteria,1VP26@1239|Firmicutes,25HRK@186801|Clostridia,3WMIB@541000|Ruminococcaceae	186801|Clostridia	S	Zinc dependent phospholipase C	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
PKFBPKFJ_00943	457412.RSAG_00228	0.0	1064.0	COG0791@1|root,COG0791@2|Bacteria,1UVPP@1239|Firmicutes,25KKC@186801|Clostridia,3WQIY@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
PKFBPKFJ_00945	457412.RSAG_00227	0.0	1257.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3WHN6@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HATPase_c,HD,HD_5,Response_reg
PKFBPKFJ_00946	1121115.AXVN01000064_gene4020	0.0	1401.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TPJ8@1239|Firmicutes,24809@186801|Clostridia,3XYIK@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	ptsG	-	2.7.1.199	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	M00809	R02738	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.1.13,4.A.1.1.14,4.A.1.1.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
PKFBPKFJ_00947	1121115.AXVN01000064_gene4021	2.15e-197	547.0	COG3711@1|root,COG3711@2|Bacteria,1TQJJ@1239|Firmicutes,249XA@186801|Clostridia,3Y2CD@572511|Blautia	186801|Clostridia	K	CAT RNA binding domain	bglG	-	-	ko:K03480	-	-	-	-	ko00000,ko03000	-	-	-	CAT_RBD,PRD
PKFBPKFJ_00948	1121115.AXVN01000064_gene4022	0.0	1738.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	1239|Firmicutes	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
PKFBPKFJ_00949	1121115.AXVN01000064_gene4023	0.0	896.0	COG0840@1|root,COG2199@1|root,COG0840@2|Bacteria,COG2199@2|Bacteria,1TQG9@1239|Firmicutes,249KA@186801|Clostridia,3Y0T6@572511|Blautia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
PKFBPKFJ_00952	1121115.AXVN01000064_gene4025	2.14e-198	550.0	28JN4@1|root,31UVI@2|Bacteria,1V2P0@1239|Firmicutes,25EHE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00953	1121115.AXVN01000064_gene4026	4.71e-155	434.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,3Y0B2@572511|Blautia	186801|Clostridia	Q	Phosphate propanoyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PTAC
PKFBPKFJ_00954	457412.RSAG_00217	4.58e-291	793.0	COG5279@1|root,COG5279@2|Bacteria,1TY2Q@1239|Firmicutes,24BDS@186801|Clostridia,3WRJG@541000|Ruminococcaceae	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PKFBPKFJ_00955	457412.RSAG_00216	4.47e-160	451.0	29XH2@1|root,30J7P@2|Bacteria,1VSYJ@1239|Firmicutes,259SM@186801|Clostridia,3WQM3@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00956	457412.RSAG_00215	8.44e-118	337.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,3WIUH@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
PKFBPKFJ_00957	1121115.AXVN01000025_gene946	0.0	1071.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia,3XZ1S@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
PKFBPKFJ_00958	1121115.AXVN01000025_gene947	2.17e-93	272.0	COG1959@1|root,COG1959@2|Bacteria,1VA5B@1239|Firmicutes,24JMN@186801|Clostridia,3Y09T@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
PKFBPKFJ_00959	1121115.AXVN01000025_gene948	0.0	2336.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3XZ4K@572511|Blautia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
PKFBPKFJ_00960	1121115.AXVN01000025_gene949	0.0	1775.0	COG4485@1|root,COG4485@2|Bacteria,1TPVY@1239|Firmicutes,24A98@186801|Clostridia,3Y056@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YfhO
PKFBPKFJ_00961	1121115.AXVN01000025_gene950	4.92e-219	605.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,3XYSZ@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	ko:K20534	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	Glycos_transf_2
PKFBPKFJ_00962	1121115.AXVN01000025_gene951	1.77e-89	263.0	COG2246@1|root,COG2246@2|Bacteria,1VESW@1239|Firmicutes,257NM@186801|Clostridia,3Y0BG@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
PKFBPKFJ_00963	1121115.AXVN01000025_gene952	6.24e-245	673.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,3XYHW@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
PKFBPKFJ_00964	1121115.AXVN01000025_gene953	3.68e-125	356.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,3Y004@572511|Blautia	186801|Clostridia	H	COG COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
PKFBPKFJ_00965	1121115.AXVN01000025_gene954	4.31e-183	509.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,3Y00I@572511|Blautia	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
PKFBPKFJ_00966	1121115.AXVN01000025_gene955	4.69e-86	253.0	COG2087@1|root,COG2087@2|Bacteria,1VG8S@1239|Firmicutes,24QSM@186801|Clostridia,3Y0HX@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	CobU
PKFBPKFJ_00967	1121115.AXVN01000025_gene956	2.18e-149	419.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3XZUY@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
PKFBPKFJ_00968	1121115.AXVN01000025_gene957	0.0	915.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3XZEP@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	ssnA	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
PKFBPKFJ_00969	457412.RSAG_00202	0.0	1972.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TPR4@1239|Firmicutes,248TM@186801|Clostridia,3WRQE@541000|Ruminococcaceae	186801|Clostridia	C	FAD binding domain	-	-	1.97.1.9	ko:K12527	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
PKFBPKFJ_00970	1121115.AXVN01000025_gene959	0.0	1754.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3XYY3@572511|Blautia	186801|Clostridia	C	COG COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	mop	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
PKFBPKFJ_00971	457412.RSAG_00200	3.71e-94	276.0	COG1148@1|root,COG1148@2|Bacteria,1V4P9@1239|Firmicutes,24IV2@186801|Clostridia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
PKFBPKFJ_00972	457412.RSAG_00199	0.0	1512.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WHIV@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhA	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
PKFBPKFJ_00973	1121115.AXVN01000025_gene962	4.7e-205	568.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia,3XZ4A@572511|Blautia	186801|Clostridia	C	COG COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs	xdhB	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
PKFBPKFJ_00974	1121115.AXVN01000025_gene963	4.4e-117	335.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24FZI@186801|Clostridia,3XZZI@572511|Blautia	186801|Clostridia	C	COG COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	cutS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
PKFBPKFJ_00975	457412.RSAG_00196	2.75e-212	586.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3WI66@541000|Ruminococcaceae	186801|Clostridia	S	Selenium-dependent molybdenum hydroxylase system protein, YqeB family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
PKFBPKFJ_00976	457412.RSAG_00195	2.58e-165	462.0	COG1763@1|root,COG1763@2|Bacteria,1VAIZ@1239|Firmicutes,24N6J@186801|Clostridia,3WKRV@541000|Ruminococcaceae	186801|Clostridia	H	selenium-dependent hydroxylase accessory protein YqeC	yqeC	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00977	457412.RSAG_04726	4.3e-159	446.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24KIZ@186801|Clostridia,3WKNV@541000|Ruminococcaceae	186801|Clostridia	S	MobA-like NTP transferase domain	ygfJ	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
PKFBPKFJ_00978	1121115.AXVN01000134_gene411	2.38e-224	618.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,3XZFB@572511|Blautia	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
PKFBPKFJ_00979	1121115.AXVN01000134_gene412	7.38e-295	803.0	COG0078@1|root,COG0078@2|Bacteria,1TNY4@1239|Firmicutes,249P4@186801|Clostridia,3XYQV@572511|Blautia	186801|Clostridia	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	ygeW	-	-	-	-	-	-	-	-	-	-	-	OTCace,OTCace_N
PKFBPKFJ_00980	1121115.AXVN01000134_gene413	0.0	900.0	COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,3XYM0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
PKFBPKFJ_00981	1121115.AXVN01000134_gene414	3.32e-304	828.0	COG1171@1|root,COG1171@2|Bacteria,1TR70@1239|Firmicutes,2485T@186801|Clostridia,3XZ80@572511|Blautia	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	dpaL	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
PKFBPKFJ_00982	457412.RSAG_00190	3.78e-312	848.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,3WK6T@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
PKFBPKFJ_00983	1121115.AXVN01000032_gene374	2.33e-32	119.0	28SNZ@1|root,2ZEZ7@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_00985	1121115.AXVN01000032_gene376	0.0	1110.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,3XYGQ@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
PKFBPKFJ_00986	1121115.AXVN01000032_gene377	0.0	1520.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3XZ2A@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
PKFBPKFJ_00987	1121115.AXVN01000032_gene378	1.28e-186	517.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,3XYYY@572511|Blautia	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
PKFBPKFJ_00988	1121115.AXVN01000032_gene379	0.0	1677.0	COG0500@1|root,COG3608@1|root,COG2226@2|Bacteria,COG3608@2|Bacteria,1UZDT@1239|Firmicutes,24BYA@186801|Clostridia,3XZ0I@572511|Blautia	186801|Clostridia	Q	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA,Methyltransf_11
PKFBPKFJ_00989	457412.RSAG_00183	6.12e-193	536.0	COG3773@1|root,COG3773@2|Bacteria,1VAUD@1239|Firmicutes,25B1B@186801|Clostridia	186801|Clostridia	M	Cell wall hydrolase	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2,LysM
PKFBPKFJ_00990	1121115.AXVN01000032_gene381	0.0	973.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3XZ3J@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
PKFBPKFJ_00991	1121115.AXVN01000032_gene382	3.07e-267	730.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia,3XZFA@572511|Blautia	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
PKFBPKFJ_00992	1121115.AXVN01000032_gene383	3.94e-200	556.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,3XZ63@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
PKFBPKFJ_00993	457412.RSAG_00178	2.23e-202	561.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3WGRJ@541000|Ruminococcaceae	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
PKFBPKFJ_00994	1121115.AXVN01000032_gene385	0.0	1665.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3XYXU@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
PKFBPKFJ_00995	1121115.AXVN01000032_gene386	5.69e-259	710.0	COG0457@1|root,COG0457@2|Bacteria,1UZDE@1239|Firmicutes,2491Z@186801|Clostridia,3XZZR@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,Fn3_assoc,TPR_16,TPR_19,TPR_8,zinc_ribbon_2
PKFBPKFJ_00996	457412.RSAG_00175	7.39e-108	311.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,3WIDB@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
PKFBPKFJ_00997	1121115.AXVN01000032_gene388	4.42e-141	397.0	COG5423@1|root,COG5423@2|Bacteria,1V5IN@1239|Firmicutes,24JW6@186801|Clostridia,3XZUH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
PKFBPKFJ_00998	1121115.AXVN01000032_gene389	1.34e-61	189.0	2DVZX@1|root,33XWD@2|Bacteria,1U4E1@1239|Firmicutes,24VHN@186801|Clostridia,3Y0V7@572511|Blautia	186801|Clostridia	S	COG NOG13846 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	YabP
PKFBPKFJ_00999	457412.RSAG_00172	6.2e-285	778.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia,3WJNK@541000|Ruminococcaceae	186801|Clostridia	S	sporulation protein	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
PKFBPKFJ_01000	1121115.AXVN01000032_gene391	7.09e-228	629.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,3XYTC@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
PKFBPKFJ_01001	457412.RSAG_00169	3.35e-111	320.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3WIDY@541000|Ruminococcaceae	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
PKFBPKFJ_01002	457412.RSAG_00167	4.99e-191	531.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,3WGZ7@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
PKFBPKFJ_01003	1121115.AXVN01000032_gene394	2.05e-42	139.0	COG4224@1|root,COG4224@2|Bacteria,1TUAX@1239|Firmicutes,24QS9@186801|Clostridia,3Y0QD@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
PKFBPKFJ_01004	1121115.AXVN01000032_gene395	4.28e-131	372.0	COG0212@1|root,COG0212@2|Bacteria,1VA91@1239|Firmicutes,24N7H@186801|Clostridia,3XZW4@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	fthC	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
PKFBPKFJ_01005	1121115.AXVN01000032_gene396	8.03e-295	805.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,3XZ50@572511|Blautia	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PKFBPKFJ_01006	1121115.AXVN01000032_gene397	0.0	1012.0	2DUK2@1|root,33R10@2|Bacteria,1VR47@1239|Firmicutes,24Z5G@186801|Clostridia,3Y0TJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01007	1121115.AXVN01000032_gene398	2.89e-222	612.0	COG2866@1|root,COG2866@2|Bacteria,1UEH5@1239|Firmicutes,25JE5@186801|Clostridia,3Y01R@572511|Blautia	186801|Clostridia	E	Zinc carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14
PKFBPKFJ_01008	457412.RSAG_00161	0.0	918.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,3WGSQ@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
PKFBPKFJ_01009	457412.RSAG_00160	1.51e-313	855.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_01010	457412.RSAG_00159	1.36e-66	202.0	COG1937@1|root,COG1937@2|Bacteria,1VEF5@1239|Firmicutes,24QRR@186801|Clostridia,3WJZ3@541000|Ruminococcaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
PKFBPKFJ_01011	1121115.AXVN01000032_gene402	0.0	1640.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3XZ6B@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
PKFBPKFJ_01012	457412.RSAG_00157	3.12e-250	687.0	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia,3WH29@541000|Ruminococcaceae	186801|Clostridia	M	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
PKFBPKFJ_01013	1121115.AXVN01000032_gene404	1.33e-135	385.0	COG1595@1|root,COG1595@2|Bacteria,1VH54@1239|Firmicutes,25MQV@186801|Clostridia,3Y22P@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_01014	457412.RSAG_04724	3.76e-72	218.0	2EBCY@1|root,335DN@2|Bacteria,1VF9P@1239|Firmicutes,24KM6@186801|Clostridia,3WMHH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01015	457412.RSAG_00154	1.41e-154	433.0	COG2206@1|root,COG2206@2|Bacteria,1UKHX@1239|Firmicutes,25FXF@186801|Clostridia,3WP2X@541000|Ruminococcaceae	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01016	457412.RSAG_04723	7.21e-143	403.0	COG2339@1|root,COG2339@2|Bacteria,1V3JI@1239|Firmicutes,24AZQ@186801|Clostridia,3WIYQ@541000|Ruminococcaceae	186801|Clostridia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
PKFBPKFJ_01017	457412.RSAG_00152	1.78e-73	220.0	2E82Y@1|root,332GY@2|Bacteria,1VEU7@1239|Firmicutes,24P37@186801|Clostridia,3WQMH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01018	457412.RSAG_00151	0.0	2010.0	COG3210@1|root,COG5492@1|root,COG3210@2|Bacteria,COG5492@2|Bacteria,1VUQN@1239|Firmicutes,24CDA@186801|Clostridia,3WMH8@541000|Ruminococcaceae	186801|Clostridia	N	Bacterial Ig-like domain 2	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CAP,DUF4430,F5_F8_type_C,FIVAR,Flg_new,RHS_repeat,SH3_3,SLH,fn3
PKFBPKFJ_01019	457412.RSAG_00150	9.1e-163	455.0	COG2452@1|root,COG2452@2|Bacteria,1UZ1U@1239|Firmicutes,24F52@186801|Clostridia,3WNIU@541000|Ruminococcaceae	186801|Clostridia	L	MerR family regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1,Resolvase
PKFBPKFJ_01020	457412.RSAG_00149	4.62e-255	702.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,3WJIU@541000|Ruminococcaceae	186801|Clostridia	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
PKFBPKFJ_01021	457412.RSAG_00148	8.36e-296	807.0	COG4826@1|root,COG4826@2|Bacteria,1UYKX@1239|Firmicutes,24B76@186801|Clostridia,3WGCD@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the serpin family	-	-	-	ko:K13963	ko05146,map05146	-	-	-	ko00000,ko00001	-	-	-	Dockerin_1,Serpin
PKFBPKFJ_01022	457412.RSAG_00147	1.79e-121	346.0	COG4637@1|root,COG4637@2|Bacteria,1UZCB@1239|Firmicutes,248WE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
PKFBPKFJ_01023	457412.RSAG_00145	0.0	1707.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3WGM4@541000|Ruminococcaceae	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
PKFBPKFJ_01024	457412.RSAG_00144	0.0	1318.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3WHC5@541000|Ruminococcaceae	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
PKFBPKFJ_01025	457412.RSAG_00143	1.13e-222	614.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3WGGD@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
PKFBPKFJ_01026	1121115.AXVN01000020_gene85	1.27e-311	848.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,3XZKZ@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
PKFBPKFJ_01027	1121115.AXVN01000020_gene86	2.62e-283	774.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia,3XZAP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
PKFBPKFJ_01028	1121115.AXVN01000020_gene87	0.0	1073.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,3XZI2@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
PKFBPKFJ_01029	1121115.AXVN01000020_gene88	2.22e-171	478.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,3XZVG@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
PKFBPKFJ_01030	1121115.AXVN01000020_gene89	1.2e-240	661.0	COG1077@1|root,COG1077@2|Bacteria,1TPVU@1239|Firmicutes,248CM@186801|Clostridia,3XZ2N@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
PKFBPKFJ_01031	457412.RSAG_00137	5.94e-208	576.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,3WIMD@541000|Ruminococcaceae	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
PKFBPKFJ_01032	457412.RSAG_00136	8.38e-120	342.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia,3WJYV@541000|Ruminococcaceae	186801|Clostridia	M	rod shape-determining protein MreD	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
PKFBPKFJ_01033	457412.RSAG_00135	0.0	1862.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,3WGCH@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding protein, transpeptidase domain protein	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
PKFBPKFJ_01034	1121115.AXVN01000020_gene93	1.27e-177	496.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,3XZ45@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
PKFBPKFJ_01035	457412.RSAG_00133	1.38e-59	184.0	COG0851@1|root,COG0851@2|Bacteria,1VFST@1239|Firmicutes,24QT6@186801|Clostridia,3WJJQ@541000|Ruminococcaceae	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
PKFBPKFJ_01036	457412.RSAG_00132	1.51e-245	678.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,3WJ15@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
PKFBPKFJ_01037	457412.RSAG_00131	2.14e-279	764.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
PKFBPKFJ_01038	1121115.AXVN01000020_gene97	3.55e-127	361.0	COG1896@1|root,COG1896@2|Bacteria,1V7E8@1239|Firmicutes,24DNC@186801|Clostridia,3Y0IJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06952	-	-	-	-	ko00000	-	-	-	DUF429,HD_3
PKFBPKFJ_01039	1121115.AXVN01000020_gene98	2.24e-96	280.0	2F70J@1|root,33ZG8@2|Bacteria,1VX30@1239|Firmicutes,251WZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01040	457412.RSAG_00127	4.22e-45	145.0	2EPN8@1|root,33H8W@2|Bacteria,1VM4B@1239|Firmicutes,24VJ3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01041	1121115.AXVN01000020_gene100	2.39e-55	172.0	COG3077@1|root,COG3077@2|Bacteria,1VJC4@1239|Firmicutes,25CY3@186801|Clostridia	186801|Clostridia	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
PKFBPKFJ_01042	457412.RSAG_00125	4.54e-63	192.0	COG3041@1|root,COG3041@2|Bacteria,1VENE@1239|Firmicutes,24MW1@186801|Clostridia,3WJV4@541000|Ruminococcaceae	186801|Clostridia	S	addiction module toxin, RelE StbE family	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
PKFBPKFJ_01043	1121115.AXVN01000020_gene101	1.97e-63	193.0	2DZYH@1|root,32VN8@2|Bacteria,1VB55@1239|Firmicutes,24P04@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2442)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2442
PKFBPKFJ_01044	457412.RSAG_00123	3.18e-154	432.0	2CX3M@1|root,32T12@2|Bacteria,1VTDD@1239|Firmicutes,24Z9E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01045	1121115.AXVN01000020_gene104	4.08e-117	335.0	2C2F1@1|root,33RFH@2|Bacteria,1VSIV@1239|Firmicutes,24ZQ7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01046	457412.RSAG_00121	8.07e-163	455.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3WHDU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
PKFBPKFJ_01047	1121115.AXVN01000020_gene106	1.7e-92	270.0	COG0433@1|root,COG0433@2|Bacteria,1VF8X@1239|Firmicutes,24N9T@186801|Clostridia,3Y046@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01048	1121115.AXVN01000020_gene107	2.54e-55	172.0	2E0EA@1|root,32W0W@2|Bacteria,1VB0V@1239|Firmicutes,24R8X@186801|Clostridia,3Y20U@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01049	1121115.AXVN01000020_gene108	1.29e-258	709.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,3XYHX@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	xerS	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
PKFBPKFJ_01050	1121115.AXVN01000020_gene110	6.36e-98	284.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,3Y0GI@572511|Blautia	186801|Clostridia	S	Thioesterase-like superfamily	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
PKFBPKFJ_01051	1121115.AXVN01000020_gene111	3.91e-237	667.0	COG4942@1|root,COG5263@1|root,COG4942@2|Bacteria,COG5263@2|Bacteria,1VH35@1239|Firmicutes,25KD3@186801|Clostridia,3Y04J@572511|Blautia	186801|Clostridia	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Peptidase_M23
PKFBPKFJ_01052	1121115.AXVN01000020_gene112	0.0	937.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,3XZ5I@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
PKFBPKFJ_01053	1121115.AXVN01000020_gene113	1.58e-153	431.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia	186801|Clostridia	F	COG NOG14451 non supervised orthologous group	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
PKFBPKFJ_01054	457412.RSAG_00112	8.26e-220	606.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,3WGKV@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PKFBPKFJ_01055	1121115.AXVN01000020_gene115	2.41e-118	338.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3Y0CB@572511|Blautia	186801|Clostridia	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
PKFBPKFJ_01056	457412.RSAG_00110	3.43e-260	713.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,3WGPK@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
PKFBPKFJ_01057	457412.RSAG_00109	1.83e-180	502.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,3WJ3J@541000|Ruminococcaceae	186801|Clostridia	S	S4 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	S4
PKFBPKFJ_01058	1121115.AXVN01000020_gene118	2.07e-109	320.0	COG1799@1|root,COG1799@2|Bacteria,1VER3@1239|Firmicutes,24I9Y@186801|Clostridia,3XZSZ@572511|Blautia	186801|Clostridia	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
PKFBPKFJ_01059	1121115.AXVN01000020_gene119	1.14e-161	453.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3XYQJ@572511|Blautia	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
PKFBPKFJ_01060	457412.RSAG_00105	0.0	914.0	2DBI9@1|root,2Z9F5@2|Bacteria,1UI10@1239|Firmicutes,25E9Z@186801|Clostridia,3WIPB@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01061	1121115.AXVN01000020_gene121	4.19e-146	411.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3XYNM@572511|Blautia	186801|Clostridia	L	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
PKFBPKFJ_01062	1121115.AXVN01000020_gene122	1.23e-80	239.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,3Y07Y@572511|Blautia	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
PKFBPKFJ_01063	1121115.AXVN01000020_gene123	3.1e-143	403.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,3XYUN@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
PKFBPKFJ_01064	1121115.AXVN01000020_gene124	3.59e-154	432.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,3XZHC@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
PKFBPKFJ_01065	1121115.AXVN01000020_gene125	6e-60	185.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,3Y0BI@572511|Blautia	186801|Clostridia	J	RNA-binding protein containing KH domain, possibly ribosomal protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
PKFBPKFJ_01066	1121115.AXVN01000020_gene126	6.85e-315	857.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3XYJQ@572511|Blautia	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
PKFBPKFJ_01067	1121115.AXVN01000020_gene127	3.52e-62	190.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,3Y06C@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
PKFBPKFJ_01068	1121115.AXVN01000020_gene128	1.58e-70	212.0	COG2868@1|root,COG2868@2|Bacteria,1VCNG@1239|Firmicutes,25N63@186801|Clostridia,3Y0KN@572511|Blautia	186801|Clostridia	J	Cysteine protease Prp	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
PKFBPKFJ_01069	1121115.AXVN01000020_gene129	3.99e-64	196.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,3Y060@572511|Blautia	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
PKFBPKFJ_01070	457412.RSAG_00096	7.59e-287	784.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia,3WICU@541000|Ruminococcaceae	186801|Clostridia	J	TIGRFAM ribonuclease, Rne Rng family	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
PKFBPKFJ_01071	1121115.AXVN01000020_gene131	2.55e-165	462.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,3XZQP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
PKFBPKFJ_01072	457412.RSAG_00094	0.0	1254.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,3WHME@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
PKFBPKFJ_01073	457412.RSAG_00093	0.0	926.0	COG0507@1|root,COG0507@2|Bacteria,1TR2Y@1239|Firmicutes,24B2Q@186801|Clostridia,3WPCY@541000|Ruminococcaceae	186801|Clostridia	L	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
PKFBPKFJ_01074	1121115.AXVN01000002_gene1452	3.2e-83	246.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3Y05K@572511|Blautia	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
PKFBPKFJ_01075	1121115.AXVN01000002_gene1451	0.0	1154.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,3XZH5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
PKFBPKFJ_01076	1121115.AXVN01000002_gene1450	6.81e-45	152.0	29V65@1|root,30GJT@2|Bacteria,1UG71@1239|Firmicutes,25NFM@186801|Clostridia,3Y24B@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01077	457412.RSAG_00089	0.0	1271.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia,3WSRG@541000|Ruminococcaceae	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,SBP_bac_3
PKFBPKFJ_01078	457412.RSAG_00088	8.09e-44	142.0	COG1918@1|root,COG1918@2|Bacteria,1W4B7@1239|Firmicutes,24X2G@186801|Clostridia	186801|Clostridia	P	FeoA	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
PKFBPKFJ_01079	457412.RSAG_00087	5.05e-259	711.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3WIY7@541000|Ruminococcaceae	186801|Clostridia	J	Metallo-beta-lactamase domain protein	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
PKFBPKFJ_01080	1121115.AXVN01000002_gene1448	7.15e-122	348.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,3Y071@572511|Blautia	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
PKFBPKFJ_01081	1121115.AXVN01000002_gene1447	0.0	919.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3XZ69@572511|Blautia	186801|Clostridia	H	Citrate synthase, C-terminal domain	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
PKFBPKFJ_01082	457412.RSAG_01324	8.71e-182	513.0	COG0675@1|root,COG0675@2|Bacteria,1TQAH@1239|Firmicutes,24EGY@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
PKFBPKFJ_01084	457412.RSAG_03284	1.1e-170	476.0	COG0204@1|root,COG0204@2|Bacteria,1TTPK@1239|Firmicutes,24B6K@186801|Clostridia,3WIQF@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
PKFBPKFJ_01085	1121115.AXVN01000021_gene1720	1.81e-132	375.0	2BWC2@1|root,33RSK@2|Bacteria,1VS2M@1239|Firmicutes,24YI2@186801|Clostridia,3Y093@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01086	1121115.AXVN01000021_gene1719	0.0	1596.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,3XZN8@572511|Blautia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
PKFBPKFJ_01087	1121115.AXVN01000021_gene1718	0.0	1269.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,3XYYE@572511|Blautia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
PKFBPKFJ_01088	1121115.AXVN01000021_gene1717	4.86e-197	546.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,3XYJ8@572511|Blautia	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
PKFBPKFJ_01089	1121115.AXVN01000021_gene1716	2.14e-177	494.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,3XZ60@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
PKFBPKFJ_01090	1121115.AXVN01000021_gene1715	1.7e-205	569.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,3XYM3@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
PKFBPKFJ_01091	457412.RSAG_03291	2.32e-234	645.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,3WI7S@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
PKFBPKFJ_01092	1121115.AXVN01000021_gene1713	1.6e-140	396.0	COG0194@1|root,COG0194@2|Bacteria,1V3RZ@1239|Firmicutes,24HKC@186801|Clostridia,3XZXN@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	gmk_1	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
PKFBPKFJ_01093	1121115.AXVN01000021_gene1712	0.0	954.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3XYX4@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	speA_1	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
PKFBPKFJ_01094	1121115.AXVN01000021_gene1711	2.92e-162	454.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,3XYGU@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_01095	1121115.AXVN01000021_gene1710	4.04e-266	729.0	COG5002@1|root,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia,3XZ9P@572511|Blautia	186801|Clostridia	T	COG COG0642 Signal transduction histidine kinase	yycG_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PKFBPKFJ_01096	1121115.AXVN01000021_gene1709	1.25e-284	777.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3XZ7D@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
PKFBPKFJ_01097	1121115.AXVN01000021_gene1708	1.35e-300	821.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3XZ1V@572511|Blautia	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
PKFBPKFJ_01098	1121115.AXVN01000021_gene1707	9.12e-112	322.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia,3Y00E@572511|Blautia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
PKFBPKFJ_01099	457412.RSAG_03298	9.98e-140	394.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,3WIF0@541000|Ruminococcaceae	186801|Clostridia	S	Flavin reductase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
PKFBPKFJ_01100	457412.RSAG_03299	0.0	1090.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,3WGK7@541000|Ruminococcaceae	186801|Clostridia	C	CBS domain	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
PKFBPKFJ_01101	1121115.AXVN01000021_gene1704	3.26e-200	556.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia,3XZE6@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
PKFBPKFJ_01102	1121115.AXVN01000021_gene1703	9.78e-156	437.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,3XZH1@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	spoT	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
PKFBPKFJ_01103	1121115.AXVN01000021_gene1702	1.84e-90	266.0	2EY21@1|root,33RAZ@2|Bacteria,1VSPZ@1239|Firmicutes,24YUD@186801|Clostridia,3Y1ZI@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
PKFBPKFJ_01104	1121115.AXVN01000021_gene1701	3.77e-217	599.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3XZGB@572511|Blautia	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
PKFBPKFJ_01105	457412.RSAG_03304	0.0	1458.0	COG0457@1|root,COG0464@1|root,COG0457@2|Bacteria,COG0464@2|Bacteria,1TY3C@1239|Firmicutes,248IE@186801|Clostridia,3WGDF@541000|Ruminococcaceae	186801|Clostridia	O	Psort location Cytoplasmic, score	SpoVK	-	-	-	-	-	-	-	-	-	-	-	TPR_8
PKFBPKFJ_01106	1121115.AXVN01000021_gene1699	2.51e-261	716.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3XZEV@572511|Blautia	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
PKFBPKFJ_01107	1121115.AXVN01000021_gene1698	4.45e-42	137.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,3Y0NB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
PKFBPKFJ_01108	457412.RSAG_03307	4.51e-260	713.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,3WGZ2@541000|Ruminococcaceae	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
PKFBPKFJ_01109	1121115.AXVN01000021_gene1696	0.0	889.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,3XYQ0@572511|Blautia	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
PKFBPKFJ_01110	457412.RSAG_03309	1.37e-21	84.3	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,3WM8B@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
PKFBPKFJ_01111	457412.RSAG_03310	6.74e-80	237.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,3WKGV@541000|Ruminococcaceae	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
PKFBPKFJ_01112	457412.RSAG_03311	1.52e-47	151.0	COG0759@1|root,COG0759@2|Bacteria,1VEIG@1239|Firmicutes,24QN4@186801|Clostridia,3WKGN@541000|Ruminococcaceae	186801|Clostridia	S	Could be involved in insertion of integral membrane proteins into the membrane	yidD	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
PKFBPKFJ_01113	457412.RSAG_03312	1.95e-289	793.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,3WHYT@541000|Ruminococcaceae	186801|Clostridia	U	Membrane protein insertase, YidC Oxa1 family	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
PKFBPKFJ_01114	457412.RSAG_03313	6.44e-195	543.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3WHR4@541000|Ruminococcaceae	186801|Clostridia	S	R3H domain protein	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
PKFBPKFJ_01115	1121115.AXVN01000021_gene1692	0.0	878.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,3XYJS@572511|Blautia	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
PKFBPKFJ_01116	1121115.AXVN01000021_gene1691	0.0	1218.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,3XYJA@572511|Blautia	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
PKFBPKFJ_01117	457412.RSAG_03316	1.69e-171	478.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,3WIRQ@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
PKFBPKFJ_01118	457412.RSAG_03317	4.57e-246	677.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,3WH5S@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_01119	1121115.AXVN01000021_gene1688	2.95e-184	514.0	COG1277@1|root,COG1277@2|Bacteria,1UZXS@1239|Firmicutes,248ME@186801|Clostridia,3XYVG@572511|Blautia	186801|Clostridia	N	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3,ABC2_membrane_5
PKFBPKFJ_01120	1121115.AXVN01000021_gene1687	0.0	943.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia,3XYR3@572511|Blautia	186801|Clostridia	N	ABC-type uncharacterized transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_transp_aux
PKFBPKFJ_01121	1121115.AXVN01000021_gene1686	0.0	908.0	2DN2J@1|root,32V6S@2|Bacteria,1V1QE@1239|Firmicutes,25HR2@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4340)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
PKFBPKFJ_01122	1121115.AXVN01000021_gene1685	1.51e-233	642.0	COG0596@1|root,COG0596@2|Bacteria,1TR3M@1239|Firmicutes,24DR9@186801|Clostridia,3XYQ9@572511|Blautia	186801|Clostridia	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
PKFBPKFJ_01123	1121115.AXVN01000021_gene1684	1.32e-176	493.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3XYPE@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
PKFBPKFJ_01124	1121115.AXVN01000021_gene1683	1.03e-214	595.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3XZNQ@572511|Blautia	186801|Clostridia	K	chromosome partitioning protein	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
PKFBPKFJ_01125	1121115.AXVN01000021_gene1682	1.11e-113	327.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,3XZYE@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
PKFBPKFJ_01126	1121115.AXVN01000021_gene1681	2.28e-308	840.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3XYK5@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
PKFBPKFJ_01127	1121115.AXVN01000021_gene1680	3.81e-224	617.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia,3XZ0E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
PKFBPKFJ_01128	457412.RSAG_03327	1.33e-187	521.0	292MS@1|root,2ZQ5N@2|Bacteria,1VRQ1@1239|Firmicutes,24ZSR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01130	1121115.AXVN01000113_gene2374	1.52e-74	231.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,3XYKZ@572511|Blautia	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
PKFBPKFJ_01131	411459.RUMOBE_02085	1.14e-231	638.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,3XZD0@572511|Blautia	186801|Clostridia	S	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
PKFBPKFJ_01132	411461.DORFOR_02720	2.26e-55	173.0	2C39Y@1|root,32RBW@2|Bacteria,1V801@1239|Firmicutes,24JSG@186801|Clostridia,27WV7@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01133	411462.DORLON_01570	5.75e-88	258.0	28PX5@1|root,2ZCH7@2|Bacteria,1V32H@1239|Firmicutes,24GGF@186801|Clostridia,27WRI@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01134	411459.RUMOBE_03454	8.17e-242	663.0	COG3049@1|root,COG3049@2|Bacteria,1TPZS@1239|Firmicutes,24B0E@186801|Clostridia,3Y087@572511|Blautia	186801|Clostridia	M	COG COG3049 Penicillin V acylase and related amidases	cbh	-	3.5.1.24	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	-	R02797,R03975,R03977,R04486,R04487,R05835	RC00090,RC00096	ko00000,ko00001,ko01000	-	-	-	CBAH
PKFBPKFJ_01135	411469.EUBHAL_01643	1.29e-159	447.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,25WDM@186806|Eubacteriaceae	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
PKFBPKFJ_01136	585394.RHOM_13755	0.0	1053.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
PKFBPKFJ_01137	411463.EUBVEN_02551	0.0	875.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,25VD8@186806|Eubacteriaceae	186801|Clostridia	C	citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
PKFBPKFJ_01138	515620.EUBELI_20658	1.69e-93	273.0	28N68@1|root,2ZBB7@2|Bacteria,1UZ5P@1239|Firmicutes,24EZI@186801|Clostridia,25Y5Y@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01139	411462.DORLON_01574	0.0	960.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia,27WIC@189330|Dorea	186801|Clostridia	I	COG COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
PKFBPKFJ_01140	511680.BUTYVIB_02272	5.44e-155	435.0	COG0745@1|root,COG0745@2|Bacteria,1TSWT@1239|Firmicutes,248B6@186801|Clostridia,4C156@830|Butyrivibrio	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_01141	411469.EUBHAL_01647	1.93e-242	667.0	COG0642@1|root,COG2205@2|Bacteria,1V10X@1239|Firmicutes,249HQ@186801|Clostridia,25VS1@186806|Eubacteriaceae	186801|Clostridia	T	CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PKFBPKFJ_01142	411461.DORFOR_03004	1.43e-252	693.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,27WMG@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
PKFBPKFJ_01143	411461.DORFOR_03005	5.15e-130	369.0	COG0558@1|root,COG0558@2|Bacteria,1V4YR@1239|Firmicutes,24FWZ@186801|Clostridia,27W1S@189330|Dorea	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
PKFBPKFJ_01144	411462.DORLON_01580	8.65e-53	166.0	COG2856@1|root,COG2856@2|Bacteria,1V1KH@1239|Firmicutes,24GHH@186801|Clostridia,27WZE@189330|Dorea	186801|Clostridia	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
PKFBPKFJ_01145	411462.DORLON_01581	1.37e-248	681.0	2EB9W@1|root,335AE@2|Bacteria,1VENH@1239|Firmicutes,24YVV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01146	411462.DORLON_01582	1.07e-23	90.5	299UP@1|root,2ZWWR@2|Bacteria,1W206@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01147	742765.HMPREF9457_03295	7.73e-99	286.0	COG0454@1|root,COG0456@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,27VXG@189330|Dorea	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
PKFBPKFJ_01148	1123313.ATUT01000008_gene1808	6.4e-75	223.0	2BW9N@1|root,32QZ7@2|Bacteria,1V8SR@1239|Firmicutes,3VTHU@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01149	457412.RSAG_02194	2.42e-79	236.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3WKJ7@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix diphteria tox regulatory element	-	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
PKFBPKFJ_01150	1121115.AXVN01000146_gene775	9.01e-164	458.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,3Y00D@572511|Blautia	186801|Clostridia	F	Phosphorylase superfamily	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
PKFBPKFJ_01151	457412.RSAG_02196	1.46e-163	459.0	COG0568@1|root,COG0568@2|Bacteria,1W6ZB@1239|Firmicutes,25MJD@186801|Clostridia,3WQKW@541000|Ruminococcaceae	186801|Clostridia	K	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01159	1121115.AXVN01000146_gene773	2.48e-115	330.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,3Y05G@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
PKFBPKFJ_01160	457412.RSAG_02198	2.26e-135	383.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,3WIUM@541000|Ruminococcaceae	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
PKFBPKFJ_01161	1121115.AXVN01000146_gene771	2.72e-283	773.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,3XYQ3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
PKFBPKFJ_01162	1121115.AXVN01000146_gene770	7.16e-132	373.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,3XZ4B@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
PKFBPKFJ_01163	1121115.AXVN01000198_gene2447	7.35e-70	210.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia,3Y0GN@572511|Blautia	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
PKFBPKFJ_01164	1121115.AXVN01000198_gene2446	1.69e-33	115.0	2FGU2@1|root,348PD@2|Bacteria,1VZBU@1239|Firmicutes,252UE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01165	457412.RSAG_03402	0.0	1073.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia,3WH01@541000|Ruminococcaceae	186801|Clostridia	G	Carbohydrate kinase, FGGY family protein	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
PKFBPKFJ_01166	1121115.AXVN01000106_gene671	0.0	1024.0	COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,24A08@186801|Clostridia,3XYUS@572511|Blautia	186801|Clostridia	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
PKFBPKFJ_01167	1121115.AXVN01000106_gene670	2.74e-266	728.0	COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,24ARJ@186801|Clostridia,3Y051@572511|Blautia	186801|Clostridia	K	Periplasmic binding protein-like domain	araR	-	-	ko:K02103	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
PKFBPKFJ_01168	457412.RSAG_03399	1.74e-196	546.0	COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,24GN2@186801|Clostridia,3WK8B@541000|Ruminococcaceae	186801|Clostridia	S	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
PKFBPKFJ_01169	457412.RSAG_03398	0.0	2993.0	COG3468@1|root,COG4932@1|root,COG3468@2|Bacteria,COG4932@2|Bacteria,1VE3U@1239|Firmicutes,24KU9@186801|Clostridia	186801|Clostridia	M	outer membrane autotransporter barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01170	457412.RSAG_03397	4.83e-92	270.0	2E4RH@1|root,32ZK1@2|Bacteria,1VEUS@1239|Firmicutes,24QIW@186801|Clostridia,3WMFG@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
PKFBPKFJ_01171	1121115.AXVN01000128_gene272	7.64e-219	602.0	COG0388@1|root,COG0388@2|Bacteria,1TRMU@1239|Firmicutes,25B19@186801|Clostridia	186801|Clostridia	S	N-carbamoylputrescine amidase	aguB	-	3.5.1.53,3.5.1.6	ko:K01431,ko:K12251	ko00240,ko00330,ko00410,ko00770,ko00983,ko01100,map00240,map00330,map00410,map00770,map00983,map01100	M00046	R00905,R01152,R04666,R08228	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase
PKFBPKFJ_01172	457412.RSAG_03395	1.56e-283	772.0	COG2957@1|root,COG2957@2|Bacteria,1TQS5@1239|Firmicutes,248CP@186801|Clostridia,3WHAA@541000|Ruminococcaceae	186801|Clostridia	E	Porphyromonas-type peptidyl-arginine deiminase	aguA	-	3.5.3.12	ko:K10536	ko00330,ko01100,map00330,map01100	-	R01416	RC00177	ko00000,ko00001,ko01000	-	-	-	PAD_porph
PKFBPKFJ_01173	457412.RSAG_03394	2.5e-283	772.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia,3WGYP@541000|Ruminococcaceae	186801|Clostridia	E	carboxynorspermidine decarboxylase	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
PKFBPKFJ_01174	457412.RSAG_03393	5.82e-309	842.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,3WGMN@541000|Ruminococcaceae	186801|Clostridia	E	Saccharopine dehydrogenase	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
PKFBPKFJ_01175	1121115.AXVN01000128_gene276	9.27e-217	597.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia,3XZ5Q@572511|Blautia	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
PKFBPKFJ_01176	457412.RSAG_03391	0.0	948.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3WGP2@541000|Ruminococcaceae	186801|Clostridia	E	Orn Lys Arg decarboxylase major	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
PKFBPKFJ_01177	457412.RSAG_03390	0.0	1102.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
PKFBPKFJ_01178	1121115.AXVN01000030_gene3606	0.0	930.0	COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,2483Z@186801|Clostridia,3Y0Z4@572511|Blautia	186801|Clostridia	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
PKFBPKFJ_01179	457412.RSAG_03388	9.34e-225	619.0	COG0583@1|root,COG0583@2|Bacteria,1UYAI@1239|Firmicutes,24BA8@186801|Clostridia,3WKDZ@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_01180	1121115.AXVN01000030_gene3608	0.0	981.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XYSC@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
PKFBPKFJ_01181	457412.RSAG_03386	0.0	1018.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3WGMD@541000|Ruminococcaceae	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
PKFBPKFJ_01182	457412.RSAG_03385	1.65e-147	415.0	28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,247W6@186801|Clostridia,3WIDK@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
PKFBPKFJ_01183	1121115.AXVN01000030_gene3611	1.78e-203	563.0	COG2207@1|root,COG2207@2|Bacteria,1V48H@1239|Firmicutes,248BW@186801|Clostridia,3XZC4@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PKFBPKFJ_01184	457412.RSAG_03383	7.32e-90	264.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia,3WK1B@541000|Ruminococcaceae	186801|Clostridia	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
PKFBPKFJ_01185	1121115.AXVN01000030_gene3613	0.0	1006.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3XZAA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
PKFBPKFJ_01186	457412.RSAG_03365	0.0	913.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia,3WH2V@541000|Ruminococcaceae	186801|Clostridia	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
PKFBPKFJ_01187	1121115.AXVN01000030_gene3615	1.71e-243	671.0	28KXK@1|root,2ZADH@2|Bacteria,1V79T@1239|Firmicutes,24K1T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
PKFBPKFJ_01188	457412.RSAG_03363	4.89e-176	489.0	COG1768@1|root,COG1768@2|Bacteria,1V3XB@1239|Firmicutes,249BN@186801|Clostridia,3WIIA@541000|Ruminococcaceae	186801|Clostridia	S	Ser Thr phosphatase family protein	-	-	-	ko:K07099	-	-	-	-	ko00000	-	-	-	Metallophos
PKFBPKFJ_01189	1121115.AXVN01000030_gene3617	1.07e-120	344.0	COG0454@1|root,COG0454@2|Bacteria,1V9X4@1239|Firmicutes,24G56@186801|Clostridia,3Y07I@572511|Blautia	186801|Clostridia	K	COG COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PKFBPKFJ_01190	457412.RSAG_03361	1.18e-50	160.0	2E7R6@1|root,3326H@2|Bacteria,1VGKC@1239|Firmicutes,24QSS@186801|Clostridia,3WQM5@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01191	457412.RSAG_03360	4.1e-251	688.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,3WG84@541000|Ruminococcaceae	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
PKFBPKFJ_01192	1121115.AXVN01000030_gene3620	9.03e-184	510.0	COG0500@1|root,COG2226@2|Bacteria,1TT7G@1239|Firmicutes,24E44@186801|Clostridia,3Y0AU@572511|Blautia	186801|Clostridia	Q	NOG31153 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01193	457412.RSAG_03358	2.19e-292	797.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,3WS0T@541000|Ruminococcaceae	186801|Clostridia	H	AMP-binding enzyme	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2,LuxC
PKFBPKFJ_01194	457412.RSAG_03357	0.0	902.0	COG1964@1|root,COG1964@2|Bacteria,1TVES@1239|Firmicutes,248NC@186801|Clostridia,3WJ5T@541000|Ruminococcaceae	186801|Clostridia	S	Radical SAM superfamily	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
PKFBPKFJ_01195	1121115.AXVN01000030_gene3623	1.68e-103	298.0	2E4P6@1|root,32ZHX@2|Bacteria,1VCAE@1239|Firmicutes,24PE5@186801|Clostridia,3Y172@572511|Blautia	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
PKFBPKFJ_01196	1121115.AXVN01000030_gene3624	5.26e-128	363.0	COG0500@1|root,COG2226@2|Bacteria,1UDBU@1239|Firmicutes,25I0S@186801|Clostridia,3Y12S@572511|Blautia	186801|Clostridia	H	Hypothetical methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
PKFBPKFJ_01197	1121115.AXVN01000030_gene3625	2.77e-49	156.0	2EGAW@1|root,33A2R@2|Bacteria,1VMAM@1239|Firmicutes,24WIE@186801|Clostridia,3Y1R7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01198	457412.RSAG_03353	0.0	1514.0	COG0247@1|root,COG0493@1|root,COG0247@2|Bacteria,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WNTW@541000|Ruminococcaceae	186801|Clostridia	CE	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_20,Pyr_redox_2
PKFBPKFJ_01199	1121115.AXVN01000030_gene3627	0.0	1858.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3Y192@572511|Blautia	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	mop	-	1.2.99.7	ko:K07469	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
PKFBPKFJ_01200	1121115.AXVN01000030_gene3628	2.63e-53	167.0	2E80U@1|root,3094H@2|Bacteria,1U4EU@1239|Firmicutes,2520R@186801|Clostridia,3Y1V4@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01201	1121115.AXVN01000030_gene3629	2.39e-226	623.0	COG2005@1|root,COG2068@1|root,COG2005@2|Bacteria,COG2068@2|Bacteria,1V2BH@1239|Firmicutes,25CV9@186801|Clostridia	186801|Clostridia	S	MobA-like NTP transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,NTP_transf_3
PKFBPKFJ_01202	1121115.AXVN01000030_gene3630	1.92e-263	721.0	COG0406@1|root,COG1418@1|root,COG0406@2|Bacteria,COG1418@2|Bacteria,1TTYI@1239|Firmicutes,25KH7@186801|Clostridia,3Y1F0@572511|Blautia	186801|Clostridia	G	Histidine phosphatase superfamily (branch 1)	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
PKFBPKFJ_01203	1121115.AXVN01000030_gene3631	2.54e-244	671.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia,3Y1BH@572511|Blautia	186801|Clostridia	O	XdhC and CoxI family	pucA	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
PKFBPKFJ_01204	1121115.AXVN01000030_gene3632	1.66e-210	581.0	COG4122@1|root,COG4122@2|Bacteria,1VKRG@1239|Firmicutes,24HG7@186801|Clostridia,3Y11Q@572511|Blautia	186801|Clostridia	S	Macrocin-O-methyltransferase (TylF)	-	-	-	ko:K05303	-	-	-	-	ko00000,ko01000	-	-	-	TylF
PKFBPKFJ_01205	97139.C824_03539	3.42e-34	118.0	COG3655@1|root,COG3655@2|Bacteria,1VI2R@1239|Firmicutes,25D59@186801|Clostridia,36Q1T@31979|Clostridiaceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
PKFBPKFJ_01206	944547.ABLL_1309	4.68e-07	61.2	COG3505@1|root,COG3505@2|Bacteria,1PWIG@1224|Proteobacteria	1224|Proteobacteria	U	Type IV secretory pathway VirD4	traD	-	-	-	-	-	-	-	-	-	-	-	TraD_N,TrwB_AAD_bind
PKFBPKFJ_01207	1211844.CBLM010000085_gene3261	2.44e-29	114.0	COG1196@1|root,COG1196@2|Bacteria,1TRNI@1239|Firmicutes,3VS3K@526524|Erysipelotrichia	526524|Erysipelotrichia	D	Plasmid recombination enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PKFBPKFJ_01212	397288.C806_02995	4.76e-48	167.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,27K85@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_01213	457412.RSAG_03051	2.5e-37	139.0	COG5263@1|root,COG5492@1|root,COG5263@2|Bacteria,COG5492@2|Bacteria,1VIRC@1239|Firmicutes	1239|Firmicutes	N	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01214	457412.RSAG_03050	0.0	1337.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia,3WIA4@541000|Ruminococcaceae	186801|Clostridia	L	TopoisomeraseII	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
PKFBPKFJ_01215	457412.RSAG_03049	0.0	1450.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia,3WGU9@541000|Ruminococcaceae	186801|Clostridia	L	DNA Topoisomerase IV	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
PKFBPKFJ_01216	1121115.AXVN01000005_gene2220	9.83e-106	305.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,3Y03N@572511|Blautia	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
PKFBPKFJ_01217	457412.RSAG_03047	1.78e-254	702.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3WG8A@541000|Ruminococcaceae	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
PKFBPKFJ_01218	1121115.AXVN01000005_gene2222	4.94e-58	179.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3Y0GX@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
PKFBPKFJ_01219	457412.RSAG_03045	4.9e-64	195.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia,3WM5W@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
PKFBPKFJ_01220	457412.RSAG_03044	0.0	1601.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,3WHTD@541000|Ruminococcaceae	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
PKFBPKFJ_01221	1121115.AXVN01000005_gene2225	4.61e-84	248.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3Y0A9@572511|Blautia	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
PKFBPKFJ_01222	457412.RSAG_03042	4.01e-235	646.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3WGKS@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
PKFBPKFJ_01223	457412.RSAG_03041	1.59e-212	587.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,3WH28@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
PKFBPKFJ_01224	457412.RSAG_03040	1e-217	600.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,3WJFU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the ribF family	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
PKFBPKFJ_01225	1121115.AXVN01000005_gene2229	8.72e-53	166.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3Y0EQ@572511|Blautia	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
PKFBPKFJ_01226	457412.RSAG_03038	0.0	1361.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3WGQZ@541000|Ruminococcaceae	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
PKFBPKFJ_01227	1121115.AXVN01000005_gene2231	5.93e-115	328.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,3XZW3@572511|Blautia	186801|Clostridia	C	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
PKFBPKFJ_01228	1121115.AXVN01000005_gene2232	4.95e-120	343.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24GHG@186801|Clostridia,3XZTE@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
PKFBPKFJ_01229	457412.RSAG_03035	4.59e-292	796.0	COG3007@1|root,COG3007@2|Bacteria,1TWIF@1239|Firmicutes,249TW@186801|Clostridia,3WHZ2@541000|Ruminococcaceae	186801|Clostridia	I	Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA)	fabV	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
PKFBPKFJ_01230	457412.RSAG_03034	0.0	2387.0	COG4870@1|root,COG4886@1|root,COG5492@1|root,COG4870@2|Bacteria,COG4886@2|Bacteria,COG5492@2|Bacteria,1TVCW@1239|Firmicutes,248WA@186801|Clostridia,3WJQN@541000|Ruminococcaceae	186801|Clostridia	O	Papain family cysteine protease	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cu_amine_oxidN1,Peptidase_C1
PKFBPKFJ_01231	457412.RSAG_03033	1.03e-84	249.0	29VA6@1|root,30GQA@2|Bacteria,1UGF6@1239|Firmicutes,25NVN@186801|Clostridia,3WM9I@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
PKFBPKFJ_01232	457412.RSAG_03032	8.45e-191	528.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,3WGQM@541000|Ruminococcaceae	186801|Clostridia	L	exodeoxyribonuclease III	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
PKFBPKFJ_01233	457412.RSAG_03031	0.0	1308.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3WHZP@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycosyl hydrolase 13 family	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
PKFBPKFJ_01234	457412.RSAG_03030	1.68e-141	398.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,3WICX@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	KatE	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01235	457412.RSAG_03029	0.0	941.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,3WGAA@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
PKFBPKFJ_01236	457412.RSAG_03028	3.55e-282	769.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,3WHCZ@541000|Ruminococcaceae	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
PKFBPKFJ_01237	457412.RSAG_03027	3.22e-135	383.0	2C0IG@1|root,324G4@2|Bacteria,1UQRN@1239|Firmicutes,258HV@186801|Clostridia,3WMTD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01238	457412.RSAG_03026	0.0	1938.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25Q4H@186801|Clostridia,3WH43@541000|Ruminococcaceae	186801|Clostridia	S	Peptidase M16C associated	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C,SLH
PKFBPKFJ_01239	457412.RSAG_03025	2.37e-218	602.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,3WGJ2@541000|Ruminococcaceae	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
PKFBPKFJ_01240	1121115.AXVN01000005_gene2245	4.31e-179	498.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,3XYR9@572511|Blautia	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
PKFBPKFJ_01241	1121115.AXVN01000005_gene2246	0.0	963.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3XZ0N@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
PKFBPKFJ_01242	457412.RSAG_03022	4.1e-257	708.0	COG1914@1|root,COG1914@2|Bacteria,1TPT1@1239|Firmicutes,248DM@186801|Clostridia,3WGJU@541000|Ruminococcaceae	186801|Clostridia	P	H( )-stimulated, divalent metal cation uptake system	mntH	-	-	ko:K03322	-	-	-	-	ko00000,ko02000	2.A.55.2.6,2.A.55.3	-	-	Nramp
PKFBPKFJ_01243	1121115.AXVN01000005_gene2248	4.38e-177	493.0	COG2049@1|root,COG2049@2|Bacteria,1TTBZ@1239|Firmicutes,24A35@186801|Clostridia,3Y1MR@572511|Blautia	186801|Clostridia	E	Carboxyltransferase domain, subdomain C and D	-	-	-	-	-	-	-	-	-	-	-	-	CT_C_D
PKFBPKFJ_01244	1121115.AXVN01000005_gene2249	1.25e-241	664.0	COG1984@1|root,COG1984@2|Bacteria,1TR6U@1239|Firmicutes,2485K@186801|Clostridia,3Y17T@572511|Blautia	186801|Clostridia	E	Pfam:AHS2	kipA	-	-	ko:K06350	-	-	-	-	ko00000	-	-	-	CT_A_B
PKFBPKFJ_01245	1121115.AXVN01000005_gene2250	8.26e-96	279.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3Y0FB@572511|Blautia	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	-	Biotin_lipoyl
PKFBPKFJ_01246	457412.RSAG_03018	5.45e-312	851.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,3WHD3@541000|Ruminococcaceae	186801|Clostridia	I	acetyl-CoA carboxylase, biotin carboxylase	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
PKFBPKFJ_01247	1121115.AXVN01000005_gene2252	3.96e-178	496.0	COG1540@1|root,COG1540@2|Bacteria,1TR8X@1239|Firmicutes,249GD@186801|Clostridia,3Y0Y6@572511|Blautia	186801|Clostridia	S	LamB/YcsF family	-	-	-	ko:K07160	-	-	-	-	ko00000	-	-	-	LamB_YcsF
PKFBPKFJ_01248	1121115.AXVN01000005_gene2253	3.67e-149	419.0	COG1102@1|root,COG1102@2|Bacteria,1V5TS@1239|Firmicutes,24HRW@186801|Clostridia	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
PKFBPKFJ_01249	457412.RSAG_03014	4.02e-237	652.0	COG2358@1|root,COG2358@2|Bacteria,1TPXW@1239|Firmicutes,2489U@186801|Clostridia,3WIYW@541000|Ruminococcaceae	186801|Clostridia	S	TRAP transporter solute receptor, TAXI family	bcsP	-	-	ko:K07080	-	-	-	-	ko00000	-	-	-	NMT1_3
PKFBPKFJ_01250	457412.RSAG_03013	0.0	1209.0	COG4666@1|root,COG4666@2|Bacteria,1TP0V@1239|Firmicutes,248AI@186801|Clostridia,3WN2E@541000|Ruminococcaceae	186801|Clostridia	S	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DUF3394,DctM
PKFBPKFJ_01251	1121115.AXVN01000005_gene2256	6.39e-233	640.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,3XZI0@572511|Blautia	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
PKFBPKFJ_01252	1121115.AXVN01000005_gene2257	9.82e-263	717.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3XZ56@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
PKFBPKFJ_01253	1121115.AXVN01000005_gene2258	3.65e-220	606.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,3XZAG@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
PKFBPKFJ_01254	1121115.AXVN01000005_gene2259	1.18e-290	793.0	COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,248EY@186801|Clostridia,3Y1FI@572511|Blautia	186801|Clostridia	KQ	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25,Methyltransf_31
PKFBPKFJ_01255	1121115.AXVN01000005_gene2260	1.71e-190	527.0	COG1278@1|root,COG1278@2|Bacteria,1URQI@1239|Firmicutes,259M3@186801|Clostridia,3Y0QB@572511|Blautia	186801|Clostridia	K	Domain of unknown function (DUF3825)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3825
PKFBPKFJ_01256	1121115.AXVN01000005_gene2261	1.38e-252	692.0	COG1835@1|root,COG1835@2|Bacteria,1VIE2@1239|Firmicutes,24SHJ@186801|Clostridia	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
PKFBPKFJ_01257	1121115.AXVN01000005_gene2262	4.38e-161	452.0	2DPYM@1|root,333Z5@2|Bacteria,1VFMY@1239|Firmicutes,24SP4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01258	1121115.AXVN01000005_gene2263	3.34e-305	836.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3XYK2@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_01259	457412.RSAG_03003	0.0	1041.0	29WVX@1|root,30IHI@2|Bacteria,1UPZS@1239|Firmicutes,257M6@186801|Clostridia,3WIT7@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01260	1121115.AXVN01000005_gene2265	2.31e-297	811.0	COG2873@1|root,COG2873@2|Bacteria,1TXZ1@1239|Firmicutes,248M7@186801|Clostridia,3Y1GM@572511|Blautia	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	-	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
PKFBPKFJ_01261	1121115.AXVN01000005_gene2266	2.45e-176	493.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,3XZ84@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
PKFBPKFJ_01262	457412.RSAG_03000	1.1e-179	500.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,3WIAB@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	ssuB_2	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
PKFBPKFJ_01263	457412.RSAG_02999	2.17e-65	208.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,3WHJD@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
PKFBPKFJ_01266	457412.RSAG_00907	1.28e-205	570.0	COG0679@1|root,COG0679@2|Bacteria,1TRAI@1239|Firmicutes,24HU9@186801|Clostridia,3WPNA@541000|Ruminococcaceae	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
PKFBPKFJ_01267	457412.RSAG_00908	2.17e-214	593.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,3WI1Q@541000|Ruminococcaceae	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
PKFBPKFJ_01268	457412.RSAG_00909	3.68e-171	478.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_01269	457412.RSAG_00910	0.0	882.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGVI@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_01270	457412.RSAG_00911	2.92e-38	127.0	COG4336@1|root,COG4336@2|Bacteria,1TRY8@1239|Firmicutes,248UQ@186801|Clostridia,3WQQT@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the D-glutamate cyclase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1445
PKFBPKFJ_01271	457412.RSAG_00912	7.87e-88	257.0	COG4422@1|root,COG4422@2|Bacteria,1TPP1@1239|Firmicutes,248RZ@186801|Clostridia,3WHGZ@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4186,DUF5131
PKFBPKFJ_01272	457412.RSAG_00913	1.12e-134	381.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia,3WK2W@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
PKFBPKFJ_01273	457412.RSAG_04704	7.23e-187	517.0	2CET8@1|root,2Z7N2@2|Bacteria,1TT9T@1239|Firmicutes,24AN8@186801|Clostridia,3WIG0@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01274	457412.RSAG_00916	3.22e-213	588.0	COG1680@1|root,COG1680@2|Bacteria,1UUHI@1239|Firmicutes,24AX5@186801|Clostridia,3WSCK@541000|Ruminococcaceae	186801|Clostridia	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
PKFBPKFJ_01275	457412.RSAG_00917	4.64e-227	624.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3WHZJ@541000|Ruminococcaceae	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4,Peptidase_S9
PKFBPKFJ_01278	457412.RSAG_00919	8.42e-102	295.0	2DHAX@1|root,32U8Z@2|Bacteria,1VV1S@1239|Firmicutes,250GD@186801|Clostridia,3WM8Y@541000|Ruminococcaceae	186801|Clostridia	S	Zinc finger domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR
PKFBPKFJ_01279	457412.RSAG_00920	1.73e-248	681.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,24E6T@186801|Clostridia	186801|Clostridia	S	DHH family	-	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
PKFBPKFJ_01280	457412.RSAG_00921	0.0	1485.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3WGIX@541000|Ruminococcaceae	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoA,FeoB_C,FeoB_N,Gate
PKFBPKFJ_01281	1121115.AXVN01000002_gene1364	1.79e-57	188.0	2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24UU3@186801|Clostridia,3Y0P6@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01282	457412.RSAG_00923	0.0	1313.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3WG7A@541000|Ruminococcaceae	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
PKFBPKFJ_01283	457412.RSAG_00924	0.0	1044.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,3WH9C@541000|Ruminococcaceae	186801|Clostridia	S	DAK2 domain fusion protein YloV	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
PKFBPKFJ_01284	1121115.AXVN01000002_gene1361	2.47e-77	231.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,3Y05W@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
PKFBPKFJ_01285	457412.RSAG_00926	6.24e-39	129.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3WKM9@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
PKFBPKFJ_01286	1121115.AXVN01000002_gene1360	2.15e-81	241.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia,3Y06K@572511|Blautia	186801|Clostridia	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
PKFBPKFJ_01287	457412.RSAG_00929	2.37e-213	593.0	2E3Z2@1|root,32YW0@2|Bacteria,1VGF4@1239|Firmicutes,24PIY@186801|Clostridia,3WM1N@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2953)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
PKFBPKFJ_01288	457412.RSAG_00930	1.18e-66	202.0	2CSSR@1|root,33IRN@2|Bacteria,1VG13@1239|Firmicutes,258FD@186801|Clostridia,3WMK4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01289	1121115.AXVN01000002_gene1357	3.45e-109	313.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia,3XZUN@572511|Blautia	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
PKFBPKFJ_01290	1121115.AXVN01000002_gene1356	0.0	937.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,3XYMX@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
PKFBPKFJ_01291	1121115.AXVN01000002_gene1355	1.68e-310	848.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,3XYN1@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
PKFBPKFJ_01292	457412.RSAG_00934	0.0	1462.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,3WH8K@541000|Ruminococcaceae	186801|Clostridia	O	Peptidase U32	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
PKFBPKFJ_01293	1121115.AXVN01000002_gene1353	2.16e-84	249.0	COG3027@1|root,COG3027@2|Bacteria,1V4E5@1239|Firmicutes,24HQR@186801|Clostridia,3Y0AS@572511|Blautia	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
PKFBPKFJ_01294	1121115.AXVN01000002_gene1352	3.72e-238	655.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,3XZK8@572511|Blautia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
PKFBPKFJ_01295	457412.RSAG_00937	1.34e-131	374.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,3WIM6@541000|Ruminococcaceae	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
PKFBPKFJ_01296	1121115.AXVN01000002_gene1350	5.72e-195	540.0	COG1148@1|root,COG2878@1|root,COG1148@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,3XZFG@572511|Blautia	186801|Clostridia	C	F420-non-reducing hydrogenase	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
PKFBPKFJ_01297	1121115.AXVN01000002_gene1349	9.51e-122	348.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,3XYQD@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
PKFBPKFJ_01298	1121115.AXVN01000002_gene1348	2.48e-162	455.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,3XYKR@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
PKFBPKFJ_01299	1121115.AXVN01000002_gene1347	4.29e-128	365.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia,3XZTQ@572511|Blautia	186801|Clostridia	P	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
PKFBPKFJ_01300	1121115.AXVN01000002_gene1346	5.22e-229	631.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,3XYSH@572511|Blautia	186801|Clostridia	C	Electron transport complex	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
PKFBPKFJ_01301	1121115.AXVN01000002_gene1345	0.0	876.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XYXE@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
PKFBPKFJ_01302	457412.RSAG_00944	4.27e-252	691.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia,3WPXI@541000|Ruminococcaceae	186801|Clostridia	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
PKFBPKFJ_01303	1121115.AXVN01000002_gene1343	2.42e-154	433.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,25D1G@186801|Clostridia	186801|Clostridia	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ACPS
PKFBPKFJ_01304	1121115.AXVN01000002_gene1342	2.15e-63	194.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24T7M@186801|Clostridia,3Y25G@572511|Blautia	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
PKFBPKFJ_01305	1121115.AXVN01000002_gene1341	0.0	5905.0	COG1020@1|root,COG3320@1|root,COG1020@2|Bacteria,COG3320@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,3Y1GF@572511|Blautia	186801|Clostridia	Q	AMP-binding enzyme C-terminal domain	-	-	-	ko:K04784,ko:K12240	ko01053,map01053	-	-	-	ko00000,ko00001,ko01004,ko01008	-	-	-	AMP-binding,AMP-binding_C,Condensation,Methyltransf_12,NAD_binding_4,PP-binding,Thioesterase
PKFBPKFJ_01306	1121115.AXVN01000002_gene1340	0.0	1098.0	COG0534@1|root,COG0534@2|Bacteria,1V10K@1239|Firmicutes,24CIC@186801|Clostridia	186801|Clostridia	TV	MatE	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MatE
PKFBPKFJ_01307	457412.RSAG_00949	0.0	1217.0	COG1520@1|root,COG1520@2|Bacteria,1TQ7F@1239|Firmicutes,249BV@186801|Clostridia,3WHZZ@541000|Ruminococcaceae	186801|Clostridia	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ,PQQ_2
PKFBPKFJ_01308	1121115.AXVN01000002_gene1338	7.62e-86	253.0	2CJZW@1|root,30J0V@2|Bacteria,1UVFN@1239|Firmicutes,2596T@186801|Clostridia,3Y21H@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01309	457412.RSAG_00951	2.35e-206	570.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,3WGB9@541000|Ruminococcaceae	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
PKFBPKFJ_01310	1121115.AXVN01000002_gene1336	3.36e-124	354.0	COG4767@1|root,COG4767@2|Bacteria,1V852@1239|Firmicutes,25BHY@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
PKFBPKFJ_01311	457412.RSAG_00995	4.8e-313	851.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WH66@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	2.7.7.49	ko:K00986	-	-	-	-	ko00000,ko01000	-	-	-	GIIM,RVT_1
PKFBPKFJ_01312	457412.RSAG_00997	1.74e-170	477.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia,3WIVB@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
PKFBPKFJ_01313	1121115.AXVN01000022_gene1759	3.22e-115	335.0	2F19F@1|root,33UAG@2|Bacteria,1VUX8@1239|Firmicutes,250KD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01314	457412.RSAG_02162	1.33e-143	405.0	2CKNK@1|root,306D0@2|Bacteria,1TZJW@1239|Firmicutes,2513T@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01315	1121115.AXVN01000022_gene1761	1.92e-145	410.0	COG0746@1|root,COG0746@2|Bacteria,1UQ1Y@1239|Firmicutes,257PR@186801|Clostridia,3Y0VI@572511|Blautia	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
PKFBPKFJ_01316	457412.RSAG_02164	1.39e-128	365.0	2A753@1|root,30W0Z@2|Bacteria,1TU7M@1239|Firmicutes,25N2S@186801|Clostridia,3WMN0@541000|Ruminococcaceae	186801|Clostridia	S	Toxin ToxN, type III toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	ToxN_toxin
PKFBPKFJ_01317	457412.RSAG_02165	3.08e-241	662.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,3WHWT@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
PKFBPKFJ_01318	1121115.AXVN01000022_gene1763	3.06e-199	551.0	COG1526@1|root,COG1526@2|Bacteria,1TU8R@1239|Firmicutes,24G61@186801|Clostridia	186801|Clostridia	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
PKFBPKFJ_01319	457412.RSAG_02167	1.46e-117	336.0	COG1763@1|root,COG1763@2|Bacteria,1VFA0@1239|Firmicutes,24IYN@186801|Clostridia,3WKCP@541000|Ruminococcaceae	186801|Clostridia	H	Molybdopterin-guanine dinucleotide biosynthesis protein	mobB	-	2.7.7.77	ko:K03753,ko:K13818	ko00790,ko01100,map00790,map01100	-	R11581	-	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
PKFBPKFJ_01320	457412.RSAG_02168	2.35e-305	832.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,3WIJX@541000|Ruminococcaceae	186801|Clostridia	H	MoeA C-terminal region (domain IV)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
PKFBPKFJ_01321	457412.RSAG_02169	7.37e-103	297.0	COG2258@1|root,COG2258@2|Bacteria,1W5YX@1239|Firmicutes,255UB@186801|Clostridia	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01322	457412.RSAG_02170	1.27e-292	798.0	COG2208@1|root,COG2208@2|Bacteria,1TQUC@1239|Firmicutes,248FZ@186801|Clostridia,3WGNY@541000|Ruminococcaceae	186801|Clostridia	KT	stage II sporulation protein E	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
PKFBPKFJ_01323	1121115.AXVN01000024_gene318	0.0	1127.0	COG2221@1|root,COG4624@1|root,COG2221@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,25KD8@186801|Clostridia,3XYQ4@572511|Blautia	186801|Clostridia	C	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,PAS
PKFBPKFJ_01324	457412.RSAG_02172	0.0	1860.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,3WRQH@541000|Ruminococcaceae	186801|Clostridia	C	Molybdopterin oxidoreductase Fe4S4 domain	fdhA2	-	1.17.1.11,1.17.1.9	ko:K00123,ko:K22341	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
PKFBPKFJ_01325	457412.RSAG_02173	0.0	1222.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3WGG2@541000|Ruminococcaceae	186801|Clostridia	C	NADH ubiquinone oxidoreductase	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
PKFBPKFJ_01326	1121115.AXVN01000024_gene315	3.66e-113	324.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,3XZET@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
PKFBPKFJ_01327	457412.RSAG_02175	1.42e-268	735.0	COG3503@1|root,COG3503@2|Bacteria,1V89T@1239|Firmicutes,24KHD@186801|Clostridia,3WMMC@541000|Ruminococcaceae	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624
PKFBPKFJ_01328	457412.RSAG_02176	9.41e-164	458.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,3WIDV@541000|Ruminococcaceae	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_01329	457412.RSAG_02177	6.23e-189	527.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,3WM12@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM competence protein ComEA helix-hairpin-helix repeat	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
PKFBPKFJ_01330	1121115.AXVN01000024_gene312	4.43e-95	277.0	COG3238@1|root,COG3238@2|Bacteria,1V6J0@1239|Firmicutes,24JM9@186801|Clostridia,3Y03G@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
PKFBPKFJ_01331	742765.HMPREF9457_03056	2.19e-33	125.0	COG3408@1|root,COG3408@2|Bacteria,1UZR0@1239|Firmicutes,24V7A@186801|Clostridia	186801|Clostridia	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01332	1121115.AXVN01000024_gene310	8.94e-135	381.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,247N7@186801|Clostridia,3XZWA@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
PKFBPKFJ_01333	1121115.AXVN01000024_gene309	0.0	1276.0	COG1409@1|root,COG1409@2|Bacteria,1TSSR@1239|Firmicutes,248DJ@186801|Clostridia,3Y0EJ@572511|Blautia	186801|Clostridia	S	Purple acid Phosphatase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Metallophos,Pur_ac_phosph_N,SLH
PKFBPKFJ_01334	1121115.AXVN01000024_gene308	9.75e-315	858.0	COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,248SW@186801|Clostridia,3Y16E@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,Glyco_tranf_2_3,Glycos_transf_2,Polysacc_deac_1
PKFBPKFJ_01335	1121115.AXVN01000024_gene307	1.88e-242	667.0	COG1413@1|root,COG1413@2|Bacteria,1VCSX@1239|Firmicutes,25K0K@186801|Clostridia,3Y1V3@572511|Blautia	186801|Clostridia	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01336	1121115.AXVN01000024_gene306	0.0	1420.0	COG0457@1|root,COG0457@2|Bacteria,1TSH7@1239|Firmicutes,248J1@186801|Clostridia,3Y14T@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01337	1121115.AXVN01000024_gene305	0.0	1038.0	COG5337@1|root,COG5337@2|Bacteria,1UMDN@1239|Firmicutes,25GFF@186801|Clostridia	186801|Clostridia	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
PKFBPKFJ_01338	1121115.AXVN01000024_gene304	7e-143	405.0	COG1285@1|root,COG1285@2|Bacteria,1TRUW@1239|Firmicutes,248G4@186801|Clostridia,3Y0H7@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
PKFBPKFJ_01339	1121115.AXVN01000024_gene303	5.88e-163	456.0	COG5036@1|root,COG5036@2|Bacteria,1V27Y@1239|Firmicutes,25D4R@186801|Clostridia,3Y0DX@572511|Blautia	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
PKFBPKFJ_01340	1121115.AXVN01000024_gene302	1.34e-205	568.0	2CABP@1|root,2Z7KZ@2|Bacteria,1U7V1@1239|Firmicutes,24C2H@186801|Clostridia,3Y1UZ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01341	742765.HMPREF9457_03045	3.18e-16	76.6	2E5DD@1|root,3305D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01342	1121115.AXVN01000024_gene300	0.0	974.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1UVHK@1239|Firmicutes,24DE9@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
PKFBPKFJ_01344	1121115.AXVN01000024_gene299	3.13e-225	620.0	2EZSX@1|root,33SXM@2|Bacteria,1VS9M@1239|Firmicutes,24XHD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01345	457412.RSAG_02621	3.59e-286	785.0	COG0642@1|root,COG0642@2|Bacteria,1UKI9@1239|Firmicutes,24XZM@186801|Clostridia,3WSRW@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PKFBPKFJ_01346	1121115.AXVN01000024_gene297	4.13e-166	464.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,3Y2AV@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_01347	1121115.AXVN01000024_gene296	0.0	1347.0	COG1520@1|root,COG1520@2|Bacteria,1UKI6@1239|Firmicutes,25FXQ@186801|Clostridia	186801|Clostridia	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01348	457412.RSAG_02181	8.81e-90	262.0	COG3279@1|root,COG3279@2|Bacteria,1VAGQ@1239|Firmicutes,24Q19@186801|Clostridia	186801|Clostridia	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
PKFBPKFJ_01349	1121115.AXVN01000024_gene294	8.63e-164	459.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24DB9@186801|Clostridia,3Y0I2@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_01350	1121115.AXVN01000024_gene293	6.98e-301	822.0	COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia,3Y0QZ@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PKFBPKFJ_01351	1121115.AXVN01000024_gene292	4.73e-286	781.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3XYZW@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PKFBPKFJ_01352	1121115.AXVN01000024_gene291	1.53e-212	587.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,3XZI8@572511|Blautia	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
PKFBPKFJ_01353	457412.RSAG_02186	9.59e-287	784.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3WGSI@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
PKFBPKFJ_01354	457412.RSAG_02187	3.4e-256	701.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,3WGZJ@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
PKFBPKFJ_01355	1121115.AXVN01000024_gene288	2.07e-302	823.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3XYUF@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
PKFBPKFJ_01356	1121115.AXVN01000024_gene287	5.34e-81	240.0	2EC8D@1|root,3366W@2|Bacteria,1VEI1@1239|Firmicutes,24WC7@186801|Clostridia	186801|Clostridia	S	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
PKFBPKFJ_01357	457412.RSAG_02190	3.93e-239	661.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,25CCK@186801|Clostridia,3WH44@541000|Ruminococcaceae	186801|Clostridia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
PKFBPKFJ_01358	457412.RSAG_02191	2.04e-313	853.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3WI8P@541000|Ruminococcaceae	186801|Clostridia	F	Amidohydrolase family	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
PKFBPKFJ_01359	457412.RSAG_02192	9.63e-306	836.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,3WGX2@541000|Ruminococcaceae	186801|Clostridia	S	xanthine uracil permease family protein K06901	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
PKFBPKFJ_01360	457412.RSAG_02193	5.11e-214	592.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,3WGBT@541000|Ruminococcaceae	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PKFBPKFJ_01361	483218.BACPEC_00094	9.57e-55	170.0	2AD7W@1|root,312WU@2|Bacteria,1V7M4@1239|Firmicutes,24M52@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01362	585394.RHOM_12560	8.95e-50	163.0	28MQP@1|root,2ZAZH@2|Bacteria,1UBV0@1239|Firmicutes,24FBQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01364	397288.C806_04586	1.95e-58	192.0	28P4A@1|root,2ZBZJ@2|Bacteria,1V39Y@1239|Firmicutes,24UPB@186801|Clostridia,27JGN@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01365	1226325.HMPREF1548_06048	2.62e-47	151.0	2AJW5@1|root,31AIZ@2|Bacteria,1V7QN@1239|Firmicutes,24JQH@186801|Clostridia,36PDP@31979|Clostridiaceae	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
PKFBPKFJ_01366	742740.HMPREF9474_03075	1.32e-92	271.0	COG1595@1|root,COG1595@2|Bacteria,1UYZA@1239|Firmicutes,24HQK@186801|Clostridia,2219R@1506553|Lachnoclostridium	2|Bacteria	K	Sigma-70, region 4	phyR	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Response_reg,Sigma70_r4_2
PKFBPKFJ_01367	1226322.HMPREF1545_02567	8.78e-238	653.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,2N6PD@216572|Oscillospiraceae	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
PKFBPKFJ_01368	742738.HMPREF9460_03117	7.73e-79	234.0	COG1396@1|root,COG1396@2|Bacteria,1V50Y@1239|Firmicutes,25BHS@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_01369	1226322.HMPREF1545_02564	8.04e-70	211.0	296J0@1|root,2ZTUJ@2|Bacteria,1V3IP@1239|Firmicutes,24H9K@186801|Clostridia,2N8QM@216572|Oscillospiraceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PKFBPKFJ_01370	397291.C804_01538	2.55e-104	317.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27J4S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_01371	397291.C804_05923	4.53e-69	218.0	COG3279@1|root,COG3279@2|Bacteria,1UYHU@1239|Firmicutes,24CBK@186801|Clostridia,27MTZ@186928|unclassified Lachnospiraceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_01372	1256908.HMPREF0373_00352	5.6e-170	475.0	2DBGG@1|root,2Z94H@2|Bacteria,1V0JX@1239|Firmicutes,24CAV@186801|Clostridia,25XNI@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01373	483218.BACPEC_00100	0.0	1131.0	COG2433@1|root,COG2433@2|Bacteria,1UI5D@1239|Firmicutes,25EHI@186801|Clostridia,26CS3@186813|unclassified Clostridiales	186801|Clostridia	S	conjugal transfer protein A K01144	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PKFBPKFJ_01374	411469.EUBHAL_01186	1.05e-58	183.0	28NQR@1|root,2ZBQ4@2|Bacteria,1V3BU@1239|Firmicutes,24FVP@186801|Clostridia,25YQI@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01375	483218.BACPEC_00098	5.51e-46	148.0	2DAN3@1|root,32TVS@2|Bacteria,1VABD@1239|Firmicutes,24N3S@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PKFBPKFJ_01376	411461.DORFOR_02651	1.15e-140	398.0	COG1396@1|root,COG1396@2|Bacteria,1TRKK@1239|Firmicutes,24C0F@186801|Clostridia,27X7J@189330|Dorea	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_01377	585394.RHOM_12600	5.65e-314	855.0	COG0582@1|root,COG0582@2|Bacteria,1TSQW@1239|Firmicutes,249T6@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_01378	411469.EUBHAL_02975	3.21e-202	565.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,25VBA@186806|Eubacteriaceae	186801|Clostridia	L	Probable transposase	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
PKFBPKFJ_01379	457412.RSAG_02967	2.74e-96	280.0	COG1943@1|root,COG1943@2|Bacteria,1V3YY@1239|Firmicutes,24IB0@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS200-family protein	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
PKFBPKFJ_01380	457412.RSAG_02966	0.0	868.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WNWQ@541000|Ruminococcaceae	186801|Clostridia	V	MviN-like protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_01381	1121115.AXVN01000035_gene3823	4.71e-166	466.0	COG5438@1|root,COG5438@2|Bacteria,1TSWX@1239|Firmicutes,24AY1@186801|Clostridia,3Y1HG@572511|Blautia	186801|Clostridia	S	YibE/F-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
PKFBPKFJ_01382	457412.RSAG_02955	8.97e-253	694.0	COG5438@1|root,COG5438@2|Bacteria,1TPEV@1239|Firmicutes,249SW@186801|Clostridia,3WIF6@541000|Ruminococcaceae	186801|Clostridia	S	PFAM YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
PKFBPKFJ_01383	457412.RSAG_02954	1.2e-239	658.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,3WGRE@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
PKFBPKFJ_01384	457412.RSAG_02953	1.69e-151	426.0	COG1418@1|root,COG1418@2|Bacteria,1UI0F@1239|Firmicutes,24GIY@186801|Clostridia,3WSS1@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
PKFBPKFJ_01385	457412.RSAG_02951	5.91e-143	404.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia,3WG7B@541000|Ruminococcaceae	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
PKFBPKFJ_01386	1121115.AXVN01000035_gene3829	4.02e-304	828.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,3XYM5@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
PKFBPKFJ_01387	457412.RSAG_02949	2.06e-150	423.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,3WI82@541000|Ruminococcaceae	186801|Clostridia	S	O-methyltransferase	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
PKFBPKFJ_01388	1121115.AXVN01000035_gene3831	1.86e-89	262.0	COG1559@1|root,COG1559@2|Bacteria,1VGA6@1239|Firmicutes,24RBR@186801|Clostridia,3Y0GT@572511|Blautia	186801|Clostridia	S	YceG-like family	-	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
PKFBPKFJ_01389	1121115.AXVN01000035_gene3832	6.22e-74	221.0	COG3679@1|root,COG3679@2|Bacteria,1VH19@1239|Firmicutes,24RNC@186801|Clostridia,3Y0MG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
PKFBPKFJ_01390	457412.RSAG_02946	0.0	1228.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3WH9M@541000|Ruminococcaceae	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
PKFBPKFJ_01391	1121115.AXVN01000035_gene3834	4.26e-45	146.0	2E3Y4@1|root,32YV4@2|Bacteria,1VFRH@1239|Firmicutes,24QXW@186801|Clostridia,3Y0M4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
PKFBPKFJ_01392	457412.RSAG_02944	1.1e-93	273.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,3WJ8E@541000|Ruminococcaceae	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
PKFBPKFJ_01393	1121115.AXVN01000035_gene3836	2.28e-58	180.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,3Y0G3@572511|Blautia	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
PKFBPKFJ_01394	457412.RSAG_02942	0.0	865.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,3WG80@541000|Ruminococcaceae	186801|Clostridia	J	tRNA methylthiotransferase YqeV	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
PKFBPKFJ_01395	457412.RSAG_02941	1.61e-48	154.0	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,3WKEN@541000|Ruminococcaceae	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
PKFBPKFJ_01396	1121115.AXVN01000035_gene3839	9.19e-287	783.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,3XZ1T@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
PKFBPKFJ_01397	1121115.AXVN01000035_gene3840	5.01e-275	752.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XYUM@572511|Blautia	186801|Clostridia	E	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
PKFBPKFJ_01398	457412.RSAG_02938	7.68e-172	480.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3WIFN@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
PKFBPKFJ_01399	1121115.AXVN01000035_gene3842	2.47e-223	616.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,3XZAN@572511|Blautia	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
PKFBPKFJ_01400	457412.RSAG_02936	1.51e-177	493.0	COG0671@1|root,COG0671@2|Bacteria,1V2PZ@1239|Firmicutes,24DHR@186801|Clostridia,3WJNZ@541000|Ruminococcaceae	186801|Clostridia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
PKFBPKFJ_01401	1121115.AXVN01000035_gene3844	5.15e-269	738.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,3XYJ6@572511|Blautia	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
PKFBPKFJ_01402	1121115.AXVN01000035_gene3845	0.0	1172.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
PKFBPKFJ_01403	1121115.AXVN01000035_gene3846	3.63e-135	384.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,3XZX7@572511|Blautia	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
PKFBPKFJ_01404	1121115.AXVN01000035_gene3847	5.24e-235	648.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,3XYPX@572511|Blautia	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
PKFBPKFJ_01405	1121115.AXVN01000035_gene3848	0.0	1274.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3XZAR@572511|Blautia	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
PKFBPKFJ_01406	457412.RSAG_02930	0.0	1743.0	COG0642@1|root,COG0834@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,3WSS0@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2,HATPase_c,HisKA,Response_reg,SBP_bac_3,dCache_1
PKFBPKFJ_01407	1121115.AXVN01000035_gene3850	7.83e-153	429.0	COG1838@1|root,COG1838@2|Bacteria,1TSJ8@1239|Firmicutes,25CDD@186801|Clostridia,3Y19V@572511|Blautia	186801|Clostridia	C	Fumarase C-terminus	ttdB	-	4.2.1.2,4.2.1.32	ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
PKFBPKFJ_01408	457412.RSAG_02928	1.01e-223	615.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3WGE0@541000|Ruminococcaceae	186801|Clostridia	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.32	ko:K03779	ko00630,map00630	-	R00339	RC01382	ko00000,ko00001,ko01000	-	-	-	Fumerase
PKFBPKFJ_01409	1121115.AXVN01000035_gene3852	7.17e-280	768.0	COG1055@1|root,COG1055@2|Bacteria,1TPNN@1239|Firmicutes,24D6M@186801|Clostridia,3XZZY@572511|Blautia	186801|Clostridia	P	Sodium:sulfate symporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS,Na_sulph_symp
PKFBPKFJ_01410	1121115.AXVN01000035_gene3853	2.36e-217	599.0	COG0583@1|root,COG0583@2|Bacteria,1TQ6Y@1239|Firmicutes,25C6V@186801|Clostridia,3Y1BG@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_01411	1121115.AXVN01000035_gene3854	1.19e-74	224.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2
PKFBPKFJ_01412	1121115.AXVN01000035_gene3855	8.2e-68	205.0	COG1695@1|root,COG1695@2|Bacteria,1VIVQ@1239|Firmicutes,25CR8@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
PKFBPKFJ_01413	1121115.AXVN01000035_gene3856	1.07e-106	311.0	COG4709@1|root,COG4709@2|Bacteria,1VBG6@1239|Firmicutes,24N6S@186801|Clostridia,3Y0AR@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
PKFBPKFJ_01414	1121115.AXVN01000035_gene3857	2.62e-175	491.0	COG3595@1|root,COG3595@2|Bacteria,1VA9V@1239|Firmicutes,24QYE@186801|Clostridia,3Y0E5@572511|Blautia	186801|Clostridia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
PKFBPKFJ_01415	1121115.AXVN01000035_gene3858	3.41e-37	125.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	XK27_05700	-	-	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	M00258,M00731,M00737	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.134	-	-	FtsX
PKFBPKFJ_01416	1121115.AXVN01000035_gene3859	8.5e-91	266.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,3XZ52@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PKFBPKFJ_01417	457412.RSAG_02834	2.69e-79	235.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,3WK2T@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein AE	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
PKFBPKFJ_01418	457412.RSAG_02835	3.34e-270	738.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,3WGIZ@541000|Ruminococcaceae	186801|Clostridia	I	Stage V sporulation protein AD	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
PKFBPKFJ_01419	1121115.AXVN01000057_gene2531	2.93e-107	309.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,3Y02E@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
PKFBPKFJ_01420	1121115.AXVN01000057_gene2532	8.08e-100	289.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia,3Y0C4@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
PKFBPKFJ_01421	457412.RSAG_02838	3.2e-212	587.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3WGX6@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
PKFBPKFJ_01422	457412.RSAG_02839	9.96e-212	585.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,3WGDD@541000|Ruminococcaceae	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
PKFBPKFJ_01423	1121115.AXVN01000046_gene2988	3.83e-232	640.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,3XYJH@572511|Blautia	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
PKFBPKFJ_01424	1121115.AXVN01000046_gene2987	1.27e-50	160.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3Y2CC@572511|Blautia	186801|Clostridia	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
PKFBPKFJ_01425	1121115.AXVN01000046_gene2986	4.72e-235	651.0	COG0681@1|root,COG0681@2|Bacteria,1VGJ6@1239|Firmicutes,24SUY@186801|Clostridia,3Y28M@572511|Blautia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01426	1121115.AXVN01000046_gene2985	3.91e-66	201.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,3XZZ4@572511|Blautia	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
PKFBPKFJ_01427	1121115.AXVN01000046_gene2984	1.77e-149	420.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3XZ95@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
PKFBPKFJ_01428	1121115.AXVN01000046_gene2983	3.27e-134	381.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
PKFBPKFJ_01429	1121115.AXVN01000046_gene2982	7.84e-61	187.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,3Y06M@572511|Blautia	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
PKFBPKFJ_01430	457412.RSAG_02847	3.72e-200	554.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3WGQK@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
PKFBPKFJ_01431	1121115.AXVN01000046_gene2980	1.77e-61	188.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3Y09D@572511|Blautia	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
PKFBPKFJ_01432	1121115.AXVN01000046_gene2979	5.64e-84	248.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3XZZ2@572511|Blautia	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
PKFBPKFJ_01433	1121115.AXVN01000046_gene2978	3.41e-151	425.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3XZ7Y@572511|Blautia	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
PKFBPKFJ_01434	1121115.AXVN01000046_gene2977	1.88e-101	293.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3XYIJ@572511|Blautia	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
PKFBPKFJ_01435	457412.RSAG_02852	1.39e-36	124.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3WKVV@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
PKFBPKFJ_01436	457412.RSAG_02853	4.6e-53	166.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,3WJV0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
PKFBPKFJ_01437	1121115.AXVN01000046_gene2974	1.26e-79	236.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,3XZZG@572511|Blautia	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
PKFBPKFJ_01438	1121115.AXVN01000046_gene2973	2.29e-64	196.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3Y0BX@572511|Blautia	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
PKFBPKFJ_01439	457412.RSAG_02856	9.39e-123	350.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,3WGYQ@541000|Ruminococcaceae	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
PKFBPKFJ_01440	1121115.AXVN01000046_gene2971	4.1e-39	129.0	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,3Y0DU@572511|Blautia	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
PKFBPKFJ_01441	1121115.AXVN01000046_gene2970	8.56e-90	263.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,3Y02G@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
PKFBPKFJ_01442	1121115.AXVN01000046_gene2969	1.21e-109	317.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,3XYVK@572511|Blautia	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
PKFBPKFJ_01443	1121115.AXVN01000046_gene2968	1.22e-77	231.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3XZZX@572511|Blautia	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
PKFBPKFJ_01444	1121115.AXVN01000046_gene2967	1.46e-112	323.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
PKFBPKFJ_01445	1121115.AXVN01000046_gene2966	1.2e-33	115.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,3Y0NM@572511|Blautia	186801|Clostridia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
PKFBPKFJ_01446	1121115.AXVN01000046_gene2965	2.1e-94	276.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3XZUB@572511|Blautia	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
PKFBPKFJ_01447	457412.RSAG_02864	1.31e-302	827.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,3WG8Z@541000|Ruminococcaceae	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
PKFBPKFJ_01448	1121115.AXVN01000046_gene2963	4.7e-156	437.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3XZAB@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
PKFBPKFJ_01449	1121115.AXVN01000046_gene2962	3.05e-184	511.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3XZ5M@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
PKFBPKFJ_01450	1121115.AXVN01000046_gene2961	4.86e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3Y0HJ@572511|Blautia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
PKFBPKFJ_01451	1121115.AXVN01000046_gene2959	2.1e-78	233.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3Y043@572511|Blautia	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
PKFBPKFJ_01452	1121115.AXVN01000046_gene2958	2.78e-85	251.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3XZVK@572511|Blautia	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
PKFBPKFJ_01453	457412.RSAG_02872	5.13e-138	390.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3WH6V@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
PKFBPKFJ_01454	457412.RSAG_02873	5.58e-221	610.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3WGUM@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
PKFBPKFJ_01455	1121115.AXVN01000046_gene2955	1.28e-115	332.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,3XZ2H@572511|Blautia	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
PKFBPKFJ_01456	457412.RSAG_02876	4.99e-221	608.0	COG0584@1|root,COG0584@2|Bacteria,1TUUB@1239|Firmicutes,259V0@186801|Clostridia,3WQRJ@541000|Ruminococcaceae	186801|Clostridia	C	glycerophosphoryl diester phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01457	457412.RSAG_02877	0.0	898.0	COG0769@1|root,COG0769@2|Bacteria,1UHY9@1239|Firmicutes,25E6X@186801|Clostridia,3WHF5@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF1727)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1727,Mur_ligase_M
PKFBPKFJ_01458	457412.RSAG_02878	9.84e-180	499.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,24A80@186801|Clostridia,3WHHU@541000|Ruminococcaceae	186801|Clostridia	S	glutamine amidotransferase	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
PKFBPKFJ_01459	1121115.AXVN01000046_gene2951	6.36e-134	380.0	COG2378@1|root,COG2378@2|Bacteria,1UH6Q@1239|Firmicutes,2504G@186801|Clostridia,3Y0EB@572511|Blautia	186801|Clostridia	K	regulation of single-species biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01460	1121115.AXVN01000046_gene2950	0.0	889.0	COG4213@1|root,COG4213@2|Bacteria,1VR5M@1239|Firmicutes,24ZY3@186801|Clostridia,3Y037@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
PKFBPKFJ_01461	1121115.AXVN01000046_gene2949	4.41e-131	372.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,3XZCM@572511|Blautia	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
PKFBPKFJ_01462	1121115.AXVN01000046_gene2948	7.08e-49	155.0	2ES6S@1|root,33JRI@2|Bacteria,1VQGH@1239|Firmicutes,24WUX@186801|Clostridia,3Y0HU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01463	1121115.AXVN01000046_gene2947	3.88e-73	219.0	COG1937@1|root,COG1937@2|Bacteria,1VA7S@1239|Firmicutes,24NNH@186801|Clostridia,3Y061@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
PKFBPKFJ_01464	1121115.AXVN01000084_gene1836	4.01e-197	546.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,3XYU0@572511|Blautia	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
PKFBPKFJ_01465	1121115.AXVN01000084_gene1835	2.49e-205	568.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3XZ9N@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_01466	457412.RSAG_02887	0.0	2492.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,3WGRN@541000|Ruminococcaceae	186801|Clostridia	F	phosphoribosylformylglycinamidine synthase	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
PKFBPKFJ_01467	1121115.AXVN01000084_gene1833	2.13e-167	468.0	2EXDX@1|root,33QQG@2|Bacteria,1VTSR@1239|Firmicutes,24YUS@186801|Clostridia,3Y1G7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01468	1121115.AXVN01000084_gene1832	2.04e-31	110.0	2CJV5@1|root,34BTB@2|Bacteria,1VZ3R@1239|Firmicutes,252Y4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01469	457412.RSAG_02892	2.19e-56	175.0	2FAAA@1|root,342IX@2|Bacteria,1VY2R@1239|Firmicutes,251XQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01470	1121115.AXVN01000084_gene1830	1.52e-241	665.0	COG1135@1|root,COG1135@2|Bacteria,1TPPN@1239|Firmicutes,248PZ@186801|Clostridia,3XZSW@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system	metN	-	-	ko:K02071	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	ABC_tran,NIL
PKFBPKFJ_01471	1121115.AXVN01000084_gene1829	2.63e-135	385.0	COG2011@1|root,COG2011@2|Bacteria,1TRSY@1239|Firmicutes,24AZ9@186801|Clostridia,3XYKJ@572511|Blautia	186801|Clostridia	P	COG COG2011 ABC-type metal ion transport system, permease component	metI	-	-	ko:K02072	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	BPD_transp_1
PKFBPKFJ_01472	1121115.AXVN01000084_gene1828	9.58e-187	523.0	COG1464@1|root,COG1464@2|Bacteria,1TQAS@1239|Firmicutes,247WV@186801|Clostridia,3XZED@572511|Blautia	186801|Clostridia	M	COG COG1464 ABC-type metal ion transport system, periplasmic component surface antigen	metQ	-	-	ko:K02073	ko02010,map02010	M00238	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.24	-	-	Lipoprotein_9
PKFBPKFJ_01473	1121115.AXVN01000084_gene1827	0.0	1242.0	COG0515@1|root,COG4886@1|root,COG0515@2|Bacteria,COG4886@2|Bacteria,1V7U3@1239|Firmicutes,24G0F@186801|Clostridia,3Y202@572511|Blautia	186801|Clostridia	KLT	Protein kinase domain	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
PKFBPKFJ_01474	1121115.AXVN01000084_gene1826	9.55e-88	258.0	2E529@1|root,32ZVG@2|Bacteria,1VGFJ@1239|Firmicutes,2502W@186801|Clostridia,3Y24M@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01475	1121115.AXVN01000084_gene1825	0.0	1826.0	COG3210@1|root,COG4886@1|root,COG3210@2|Bacteria,COG4886@2|Bacteria,1UVF4@1239|Firmicutes,25KH5@186801|Clostridia,3Y235@572511|Blautia	186801|Clostridia	U	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
PKFBPKFJ_01478	457412.RSAG_03062	0.0	1420.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
PKFBPKFJ_01479	457412.RSAG_03063	0.0	992.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,3WI8N@541000|Ruminococcaceae	186801|Clostridia	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
PKFBPKFJ_01480	457412.RSAG_03064	0.0	874.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,3WH9K@541000|Ruminococcaceae	186801|Clostridia	S	ATPase (AAA superfamily)	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
PKFBPKFJ_01481	457412.RSAG_03065	1.42e-270	740.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,3WI13@541000|Ruminococcaceae	186801|Clostridia	E	Prephenate dehydratase	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
PKFBPKFJ_01482	457412.RSAG_03066	5.78e-305	832.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WGH0@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the folylpolyglutamate synthase family	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
PKFBPKFJ_01483	1121115.AXVN01000005_gene2212	1.89e-95	277.0	COG4905@1|root,COG4905@2|Bacteria,1VAQJ@1239|Firmicutes,24K5I@186801|Clostridia,3Y0E6@572511|Blautia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
PKFBPKFJ_01484	457412.RSAG_03068	1.94e-215	595.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3WG83@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the ATCase OTCase family	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
PKFBPKFJ_01485	1121115.AXVN01000005_gene2210	1.09e-100	291.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,3XZVS@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
PKFBPKFJ_01487	457412.RSAG_03070	0.0	1102.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,3WI74@541000|Ruminococcaceae	186801|Clostridia	F	Phosphoribulokinase uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
PKFBPKFJ_01488	457412.RSAG_03071	6.37e-186	516.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,3WJ9H@541000|Ruminococcaceae	186801|Clostridia	S	dinuclear metal center protein, YbgI	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
PKFBPKFJ_01489	1121115.AXVN01000005_gene2207	5.03e-166	464.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,3XZUP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
PKFBPKFJ_01490	1121115.AXVN01000005_gene2206	2.44e-234	649.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3XZ4I@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
PKFBPKFJ_01491	1121115.AXVN01000005_gene2205	0.0	1176.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3XYMV@572511|Blautia	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
PKFBPKFJ_01492	1121115.AXVN01000005_gene2204	3.45e-239	657.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,3XYN7@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
PKFBPKFJ_01494	1121115.AXVN01000073_gene2025	1.22e-308	840.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,3XZDX@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
PKFBPKFJ_01495	1469948.JPNB01000001_gene878	8.36e-33	123.0	COG0163@1|root,COG0163@2|Bacteria,1V3JV@1239|Firmicutes,24HE5@186801|Clostridia,36GMJ@31979|Clostridiaceae	186801|Clostridia	H	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN	ubiX	-	2.5.1.129	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	M00117	R01238,R02952,R03367,R04985,R04986,R11225	RC00391,RC00814,RC03392	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavoprotein
PKFBPKFJ_01496	1121115.AXVN01000073_gene2023	0.0	1132.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PKFBPKFJ_01497	457412.RSAG_03079	7.65e-154	433.0	2EX9H@1|root,33QK7@2|Bacteria,1VRP0@1239|Firmicutes,24YQ9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01498	457412.RSAG_03080	8.92e-164	459.0	COG1811@1|root,COG1811@2|Bacteria,1TQWV@1239|Firmicutes,25CHE@186801|Clostridia,3WSCZ@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF554)	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
PKFBPKFJ_01499	1121115.AXVN01000073_gene2020	0.0	957.0	COG2199@1|root,COG2199@2|Bacteria,1U78Z@1239|Firmicutes,24BM3@186801|Clostridia,3Y2A9@572511|Blautia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
PKFBPKFJ_01500	457412.RSAG_03081	1.07e-302	826.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3WGQW@541000|Ruminococcaceae	186801|Clostridia	M	Metalloprotease	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
PKFBPKFJ_01501	457412.RSAG_03082	3.23e-269	737.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3WGCN@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
PKFBPKFJ_01502	1121115.AXVN01000073_gene2017	9.99e-176	491.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,3XZGP@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score 10.00	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
PKFBPKFJ_01503	1121115.AXVN01000073_gene2016	1.9e-170	475.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,3XYZ5@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
PKFBPKFJ_01504	1121115.AXVN01000073_gene2015	1.12e-116	335.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3XZAV@572511|Blautia	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
PKFBPKFJ_01505	1121115.AXVN01000073_gene2014	1.62e-160	450.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,3XZ3X@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
PKFBPKFJ_01506	1121115.AXVN01000073_gene2013	8.21e-176	499.0	2EY3W@1|root,33RCQ@2|Bacteria,1VU3P@1239|Firmicutes,24XPJ@186801|Clostridia,3XZZ1@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01507	457412.RSAG_03088	1.59e-136	386.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3WI5H@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
PKFBPKFJ_01508	457412.RSAG_03089	1.34e-104	302.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3WIZR@541000|Ruminococcaceae	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
PKFBPKFJ_01509	457412.RSAG_03090	0.0	1460.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3WGHJ@541000|Ruminococcaceae	186801|Clostridia	J	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
PKFBPKFJ_01510	457412.RSAG_03091	1.02e-42	140.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes,25N7Y@186801|Clostridia,3WM7P@541000|Ruminococcaceae	186801|Clostridia	U	Preprotein translocase SecG subunit	-	-	-	-	-	-	-	-	-	-	-	-	SecG
PKFBPKFJ_01511	1121115.AXVN01000073_gene2008	5.2e-181	511.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3XYIB@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
PKFBPKFJ_01512	457412.RSAG_03094	0.0	1051.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia,3WGJ0@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_01513	457412.RSAG_03095	0.0	1111.0	COG1961@1|root,COG1961@2|Bacteria,1V29C@1239|Firmicutes,24GBE@186801|Clostridia	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_01514	457412.RSAG_03096	0.0	1059.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WG90@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_01516	457412.RSAG_03098	7.06e-81	239.0	COG2337@1|root,COG2337@2|Bacteria,1TTJP@1239|Firmicutes,25MHP@186801|Clostridia,3WQFT@541000|Ruminococcaceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
PKFBPKFJ_01517	457412.RSAG_03100	5.23e-107	308.0	2DBT4@1|root,2ZAVD@2|Bacteria,1V0AF@1239|Firmicutes,24DH6@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
PKFBPKFJ_01518	457412.RSAG_03101	3.04e-36	122.0	COG1733@1|root,COG1733@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HTH_34,HxlR
PKFBPKFJ_01519	457412.RSAG_03102	3.87e-169	471.0	COG2819@1|root,COG2819@2|Bacteria,1TR41@1239|Firmicutes,24EH0@186801|Clostridia,3WS55@541000|Ruminococcaceae	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
PKFBPKFJ_01520	457412.RSAG_03103	0.0	995.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,24EGZ@186801|Clostridia,3WI6H@541000|Ruminococcaceae	186801|Clostridia	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
PKFBPKFJ_01521	457412.RSAG_03104	2.6e-111	319.0	COG0454@1|root,COG0456@2|Bacteria,1VAJN@1239|Firmicutes,24H93@186801|Clostridia,3WJ4Z@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
PKFBPKFJ_01522	457412.RSAG_03106	8.12e-91	265.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia,3WKPB@541000|Ruminococcaceae	186801|Clostridia	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
PKFBPKFJ_01524	887325.HMPREF0381_1082	1.54e-50	165.0	2ET36@1|root,33KMC@2|Bacteria,1VKQN@1239|Firmicutes,24UID@186801|Clostridia,1HW30@1164882|Lachnoanaerobaculum	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
PKFBPKFJ_01525	991905.SL003B_3762	1.47e-11	62.8	2DG40@1|root,2ZUDE@2|Bacteria,1PB4J@1224|Proteobacteria,2UYN6@28211|Alphaproteobacteria	991905.SL003B_3762|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01529	891391.LAC30SC_01360	1.54e-52	187.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,4HDG6@91061|Bacilli,3F4IB@33958|Lactobacillaceae	91061|Bacilli	L	Belongs to the 'phage' integrase family	int7	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_01530	1121115.AXVN01000001_gene1082	1.92e-67	204.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,3Y0C3@572511|Blautia	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
PKFBPKFJ_01531	1121115.AXVN01000001_gene1081	3.52e-309	844.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3XZA0@572511|Blautia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
PKFBPKFJ_01532	1121115.AXVN01000001_gene1080	1.77e-51	162.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,3Y0EA@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
PKFBPKFJ_01533	1121115.AXVN01000001_gene1079	3.47e-40	133.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,3Y0D4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
PKFBPKFJ_01534	457412.RSAG_01192	1.08e-113	326.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,3WIMH@541000|Ruminococcaceae	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
PKFBPKFJ_01535	1121115.AXVN01000001_gene1077	1.29e-181	505.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,3XYT2@572511|Blautia	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
PKFBPKFJ_01536	1121115.AXVN01000001_gene1076	1.72e-251	689.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3XZ7B@572511|Blautia	186801|Clostridia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
PKFBPKFJ_01537	1121115.AXVN01000001_gene1075	1.21e-289	795.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia,3XZ2C@572511|Blautia	186801|Clostridia	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
PKFBPKFJ_01538	1121115.AXVN01000001_gene1074	1.28e-131	373.0	COG0655@1|root,COG0655@2|Bacteria,1TQKC@1239|Firmicutes,24H9P@186801|Clostridia,3Y053@572511|Blautia	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
PKFBPKFJ_01539	457412.RSAG_01094	5.39e-42	141.0	2F54G@1|root,33XRK@2|Bacteria,1VVDU@1239|Firmicutes,250QM@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01540	1121115.AXVN01000001_gene1072	1.15e-234	645.0	COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,249PP@186801|Clostridia,3XZ54@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,PTS-HPr
PKFBPKFJ_01541	457412.RSAG_01092	5.95e-301	821.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3WG99@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
PKFBPKFJ_01542	1121115.AXVN01000001_gene1070	5.93e-261	715.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,3XZI7@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
PKFBPKFJ_01543	1121115.AXVN01000001_gene1069	0.0	1377.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3XZ5X@572511|Blautia	186801|Clostridia	J	translation elongation factor G	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
PKFBPKFJ_01544	457412.RSAG_01089	0.0	1648.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,3WH0P@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
PKFBPKFJ_01545	1121115.AXVN01000001_gene1067	2.31e-311	850.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZAY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	mepA_10	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_01546	1121115.AXVN01000001_gene1066	0.0	1027.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3XYSE@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
PKFBPKFJ_01547	1121115.AXVN01000001_gene1065	0.0	1149.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,3XZD2@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
PKFBPKFJ_01548	457412.RSAG_01085	4.66e-200	555.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3WGMS@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
PKFBPKFJ_01549	457412.RSAG_01084	7.36e-55	171.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,3WJWB@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0296 family	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
PKFBPKFJ_01550	457412.RSAG_01083	8.08e-140	395.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,3WIUW@541000|Ruminococcaceae	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
PKFBPKFJ_01551	1121115.AXVN01000001_gene1061	1.63e-47	155.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes,257WP@186801|Clostridia,3Y0N6@572511|Blautia	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
PKFBPKFJ_01552	1121115.AXVN01000001_gene1060	0.0	878.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,3XYI9@572511|Blautia	186801|Clostridia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
PKFBPKFJ_01553	1121115.AXVN01000001_gene1059	7.41e-120	343.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,3XZV4@572511|Blautia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
PKFBPKFJ_01554	1121115.AXVN01000001_gene1058	1.84e-98	288.0	COG1546@1|root,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3Y099@572511|Blautia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
PKFBPKFJ_01555	1121115.AXVN01000001_gene1057	5.18e-55	172.0	2EMJQ@1|root,32KAG@2|Bacteria,1URUU@1239|Firmicutes,259SC@186801|Clostridia,3Y0NU@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01556	1121115.AXVN01000001_gene1056	5.64e-79	235.0	2BB22@1|root,324I6@2|Bacteria,1UQT3@1239|Firmicutes,258J6@186801|Clostridia,3Y0Q8@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01557	457412.RSAG_01076	3.69e-33	114.0	2FGS5@1|root,348MK@2|Bacteria,1W0U5@1239|Firmicutes,2540A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01558	1121115.AXVN01000001_gene1054	1.1e-29	109.0	2F3CT@1|root,33W6S@2|Bacteria,1VVCN@1239|Firmicutes,250TA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01559	457412.RSAG_01073	1.67e-203	577.0	COG5263@1|root,COG5263@2|Bacteria,1TPVT@1239|Firmicutes,24DEH@186801|Clostridia,3WQ86@541000|Ruminococcaceae	186801|Clostridia	M	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,LRR_5,Peptidase_C80,TcdA_TcdB,TcdA_TcdB_pore,TcdB_N
PKFBPKFJ_01560	1121115.AXVN01000001_gene1052	9.11e-302	822.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3XYHR@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
PKFBPKFJ_01561	457412.RSAG_01071	0.0	1624.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3WGEX@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
PKFBPKFJ_01562	1121115.AXVN01000001_gene1050	3.98e-29	104.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,3Y0K6@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
PKFBPKFJ_01563	1121115.AXVN01000001_gene1049	0.0	1053.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3XZ8D@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
PKFBPKFJ_01564	457412.RSAG_01068	9.92e-285	778.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,3WHE1@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
PKFBPKFJ_01565	457412.RSAG_01067	3.12e-251	689.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,3WI4Q@541000|Ruminococcaceae	186801|Clostridia	H	Psort location Cytoplasmic, score	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
PKFBPKFJ_01566	457412.RSAG_01066	4.47e-199	551.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,3WJK2@541000|Ruminococcaceae	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
PKFBPKFJ_01567	457412.RSAG_01065	1.89e-184	513.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,3WJM6@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
PKFBPKFJ_01568	457412.RSAG_01064	1.94e-129	368.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,3WJD2@541000|Ruminococcaceae	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
PKFBPKFJ_01569	1121115.AXVN01000001_gene1043	1.63e-190	528.0	COG0770@1|root,COG0770@2|Bacteria,1V1NG@1239|Firmicutes,24GE1@186801|Clostridia,3Y02I@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
PKFBPKFJ_01570	457412.RSAG_01061	2.08e-304	829.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WGET@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
PKFBPKFJ_01571	1121115.AXVN01000001_gene1041	5.59e-181	505.0	COG0703@1|root,COG1605@1|root,COG0703@2|Bacteria,COG1605@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3XZNC@572511|Blautia	186801|Clostridia	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
PKFBPKFJ_01572	1121115.AXVN01000001_gene1040	1.81e-62	191.0	2B2ZF@1|root,32PN8@2|Bacteria,1V7B5@1239|Firmicutes,24JQY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01573	457412.RSAG_01052	1.19e-08	52.4	29PJD@1|root,30AHI@2|Bacteria,1VC64@1239|Firmicutes,24N2Y@186801|Clostridia,3WQ27@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4160)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4160
PKFBPKFJ_01575	1256908.HMPREF0373_00663	5.27e-212	611.0	COG0305@1|root,COG0305@2|Bacteria,1UZIG@1239|Firmicutes,24AKK@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	3.6.4.12	ko:K17680	-	-	-	-	ko00000,ko01000,ko03029	-	-	-	AAA_25,ATPase,DnaB,DnaB_C
PKFBPKFJ_01576	1304880.JAGB01000002_gene2234	1.16e-21	99.0	2DYW6@1|root,32V64@2|Bacteria,1VDSX@1239|Firmicutes,24R5C@186801|Clostridia	186801|Clostridia	S	Bacteriophage replication protein O	-	-	-	-	-	-	-	-	-	-	-	-	Phage_rep_O
PKFBPKFJ_01577	1235798.C817_05064	7.87e-14	66.2	2EQGP@1|root,33I2P@2|Bacteria,1VKY1@1239|Firmicutes,24US2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01578	500632.CLONEX_03572	5.19e-25	94.7	2DE0W@1|root,2ZK1Y@2|Bacteria,1W4QD@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01579	929794.CALV01000022_gene769	0.000435	46.2	COG1396@1|root,COG1396@2|Bacteria,1N8AN@1224|Proteobacteria,2UA25@28211|Alphaproteobacteria,48U4Q@772|Bartonellaceae	28211|Alphaproteobacteria	K	HTH-type transcriptional regulator dicA (Repressor of division inhibition gene dicB) (P06966 in E. coli)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_01580	1121115.AXVN01000001_gene1093	1.99e-285	780.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3XYJM@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
PKFBPKFJ_01581	1121115.AXVN01000001_gene1094	2.08e-215	596.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3XZT9@572511|Blautia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
PKFBPKFJ_01582	457412.RSAG_04662	0.0	1937.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,3WH4V@541000|Ruminococcaceae	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
PKFBPKFJ_01583	1121115.AXVN01000001_gene1096	8.03e-159	445.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3XZ9W@572511|Blautia	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
PKFBPKFJ_01584	1121115.AXVN01000001_gene1097	6.78e-42	137.0	COG0236@1|root,COG0236@2|Bacteria,1UGNP@1239|Firmicutes,25P5Y@186801|Clostridia,3Y0KT@572511|Blautia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
PKFBPKFJ_01585	1121115.AXVN01000001_gene1098	2.06e-236	651.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,3XYGR@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
PKFBPKFJ_01586	457412.RSAG_01204	0.0	1158.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,3WGT9@541000|Ruminococcaceae	186801|Clostridia	S	ABC transporter	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
PKFBPKFJ_01587	457412.RSAG_01205	1.16e-177	496.0	2ESCZ@1|root,33JXR@2|Bacteria,1VRFX@1239|Firmicutes,24YXB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01588	457412.RSAG_01206	7.7e-168	469.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24C2K@186801|Clostridia,3WRJJ@541000|Ruminococcaceae	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_01589	1121115.AXVN01000001_gene1102	0.0	1203.0	COG3290@1|root,COG5002@1|root,COG3290@2|Bacteria,COG5002@2|Bacteria,1VC62@1239|Firmicutes,25E8N@186801|Clostridia,3Y0QU@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PKFBPKFJ_01590	457412.RSAG_01208	0.0	1313.0	2E7W1@1|root,332AT@2|Bacteria,1UYG9@1239|Firmicutes,24B0R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01591	1121115.AXVN01000001_gene1104	1.66e-308	843.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYPG@572511|Blautia	186801|Clostridia	V	COG COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_01592	1121115.AXVN01000001_gene1105	3.15e-38	127.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3Y0IR@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
PKFBPKFJ_01593	457412.RSAG_01211	2.07e-124	354.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,3WJHK@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized ACR, COG1399	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
PKFBPKFJ_01594	457412.RSAG_01212	1.21e-305	833.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3WH48@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
PKFBPKFJ_01595	457412.RSAG_01213	1.34e-232	641.0	COG0280@1|root,COG0280@2|Bacteria,1TPQ0@1239|Firmicutes,247W9@186801|Clostridia,3WGX7@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Phosphate acetyl butaryl transferase	pta	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
PKFBPKFJ_01596	457412.RSAG_04661	9.09e-314	856.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,3WI9X@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the UPF0348 family	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
PKFBPKFJ_01597	1121115.AXVN01000001_gene1110	3.25e-180	502.0	COG2865@1|root,COG2865@2|Bacteria,1TQXE@1239|Firmicutes,249ND@186801|Clostridia,3XZUK@572511|Blautia	186801|Clostridia	K	COG NOG11764 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01598	1121115.AXVN01000001_gene1111	1.51e-85	253.0	COG1340@1|root,COG1340@2|Bacteria,1V7S0@1239|Firmicutes,24KZW@186801|Clostridia	186801|Clostridia	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
PKFBPKFJ_01599	457412.RSAG_01218	5.84e-92	271.0	2CJ2H@1|root,33QUA@2|Bacteria,1VSMM@1239|Firmicutes,24Z9D@186801|Clostridia	186801|Clostridia	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
PKFBPKFJ_01600	1121115.AXVN01000001_gene1113	2.95e-301	822.0	COG0038@1|root,COG0038@2|Bacteria,1UZ4F@1239|Firmicutes,24921@186801|Clostridia	186801|Clostridia	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
PKFBPKFJ_01601	1121115.AXVN01000001_gene1114	6.37e-188	522.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3Y16A@572511|Blautia	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
PKFBPKFJ_01602	457412.RSAG_01221	2.57e-200	557.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3WGQG@541000|Ruminococcaceae	186801|Clostridia	P	Branched-chain amino acid ABC transporter, permease protein	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
PKFBPKFJ_01603	1121115.AXVN01000001_gene1116	3.29e-235	648.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3XZPA@572511|Blautia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PKFBPKFJ_01604	457412.RSAG_01223	1.2e-260	714.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3WHN4@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	hisC	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
PKFBPKFJ_01605	457412.RSAG_01224	0.0	870.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,3WGZM@541000|Ruminococcaceae	186801|Clostridia	S	UPF0210 protein	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
PKFBPKFJ_01606	1121115.AXVN01000001_gene1119	3.78e-57	177.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,3Y0FS@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
PKFBPKFJ_01607	1121115.AXVN01000001_gene1120	1.25e-194	539.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,3XYGN@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
PKFBPKFJ_01608	1121115.AXVN01000001_gene1121	2.34e-140	396.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,3Y05Z@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
PKFBPKFJ_01609	457412.RSAG_01228	0.0	1792.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3WGRT@541000|Ruminococcaceae	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
PKFBPKFJ_01610	1121115.AXVN01000001_gene1123	1.61e-73	221.0	2ETPV@1|root,33M7I@2|Bacteria,1VNHF@1239|Firmicutes,25A5M@186801|Clostridia,3Y0Q4@572511|Blautia	186801|Clostridia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
PKFBPKFJ_01611	1121115.AXVN01000001_gene1124	0.0	1221.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XZ55@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
PKFBPKFJ_01612	457412.RSAG_04591	1.22e-268	738.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
PKFBPKFJ_01613	1121115.AXVN01000010_gene2747	1.06e-145	410.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_01614	457412.RSAG_01448	0.0	1422.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia,3WH88@541000|Ruminococcaceae	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
PKFBPKFJ_01616	457412.RSAG_01447	3.01e-297	809.0	COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,248GV@186801|Clostridia,3WN9Q@541000|Ruminococcaceae	186801|Clostridia	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
PKFBPKFJ_01617	1121115.AXVN01000010_gene2761	1.77e-62	191.0	COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,24MN2@186801|Clostridia	186801|Clostridia	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
PKFBPKFJ_01618	1121115.AXVN01000010_gene2762	3.91e-82	243.0	COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,24N65@186801|Clostridia	186801|Clostridia	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
PKFBPKFJ_01619	457412.RSAG_01445	0.0	1151.0	COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,24D62@186801|Clostridia,3WGSE@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
PKFBPKFJ_01621	1121115.AXVN01000010_gene2764	3.75e-119	340.0	2DC0F@1|root,2ZC7C@2|Bacteria,1UPV2@1239|Firmicutes,25HPJ@186801|Clostridia	186801|Clostridia	S	AmiS/UreI family transporter	-	-	-	ko:K03191	ko05120,map05120	-	-	-	ko00000,ko00001,ko02000	1.A.29.1.3,1.A.29.1.4,1.A.29.1.5	-	-	AmiS_UreI
PKFBPKFJ_01622	1121115.AXVN01000010_gene2765	1.82e-112	322.0	COG2371@1|root,COG2371@2|Bacteria,1V7SB@1239|Firmicutes,25DT7@186801|Clostridia	186801|Clostridia	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
PKFBPKFJ_01623	1121115.AXVN01000010_gene2766	7.42e-161	451.0	COG0830@1|root,COG0830@2|Bacteria,1V2H0@1239|Firmicutes,24ETM@186801|Clostridia	186801|Clostridia	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
PKFBPKFJ_01624	1121115.AXVN01000010_gene2767	6.7e-141	398.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,3XZ4U@572511|Blautia	186801|Clostridia	KO	UreA amidohydrolase (urease) regulatory and maturation protein UreG	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
PKFBPKFJ_01625	1121115.AXVN01000010_gene2768	4.15e-200	555.0	COG0829@1|root,COG0829@2|Bacteria,1TVM2@1239|Firmicutes,24D1J@186801|Clostridia	186801|Clostridia	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
PKFBPKFJ_01626	180332.JTGN01000004_gene2620	2.43e-185	549.0	COG1609@1|root,COG1879@1|root,COG1609@2|Bacteria,COG1879@2|Bacteria,1TS5P@1239|Firmicutes,24E9X@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3,Peripla_BP_4
PKFBPKFJ_01627	97139.C824_03759	3.1e-127	369.0	COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,24AF7@186801|Clostridia,36GBX@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
PKFBPKFJ_01628	97139.C824_03760	4.23e-150	436.0	COG1879@1|root,COG1879@2|Bacteria,1TSN1@1239|Firmicutes,249RI@186801|Clostridia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
PKFBPKFJ_01629	887325.HMPREF0381_2858	4.71e-225	635.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,1HVMT@1164882|Lachnoanaerobaculum	186801|Clostridia	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K02056,ko:K17204	ko02010,map02010	M00221,M00590	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.11,3.A.1.2.16	-	-	ABC_tran
PKFBPKFJ_01630	887325.HMPREF0381_2857	1.61e-151	434.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,1HUGI@1164882|Lachnoanaerobaculum	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
PKFBPKFJ_01631	887325.HMPREF0381_2856	5.21e-244	674.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
PKFBPKFJ_01632	1410632.JHWW01000002_gene2166	1.57e-92	287.0	COG0673@1|root,COG0673@2|Bacteria,1TQFW@1239|Firmicutes,24BIG@186801|Clostridia,27KU6@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
PKFBPKFJ_01633	500635.MITSMUL_05537	7.54e-194	540.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,4H77A@909932|Negativicutes	909932|Negativicutes	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
PKFBPKFJ_01634	97139.C824_03757	2.79e-256	706.0	COG0673@1|root,COG0673@2|Bacteria,1TSWE@1239|Firmicutes,24DSM@186801|Clostridia,36M2M@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
PKFBPKFJ_01635	1280698.AUJS01000033_gene2056	9.24e-234	654.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,27WBY@189330|Dorea	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_01636	1298920.KI911353_gene4374	8.96e-188	530.0	COG1879@1|root,COG1879@2|Bacteria,1UE0M@1239|Firmicutes,24C7Y@186801|Clostridia,2246U@1506553|Lachnoclostridium	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
PKFBPKFJ_01637	411459.RUMOBE_00014	1.36e-249	697.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3XZ1W@572511|Blautia	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441,ko:K10542	ko02010,map02010	M00212,M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19,3.A.1.2.3	-	-	ABC_tran
PKFBPKFJ_01638	411459.RUMOBE_00013	5.38e-183	516.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,3Y07K@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
PKFBPKFJ_01639	1121115.AXVN01000010_gene2773	8.62e-76	226.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,3Y05X@572511|Blautia	186801|Clostridia	P	Belongs to the ArsC family	spxA	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
PKFBPKFJ_01640	1121115.AXVN01000010_gene2774	3.8e-21	92.8	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01641	1121115.AXVN01000010_gene2774	4.98e-24	98.6	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01642	1121115.AXVN01000010_gene2775	2.29e-88	259.0	COG1433@1|root,COG1433@2|Bacteria,1V7KS@1239|Firmicutes,24MUB@186801|Clostridia,3Y06A@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
PKFBPKFJ_01643	1121115.AXVN01000010_gene2776	1.86e-187	523.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,3XYMF@572511|Blautia	186801|Clostridia	P	COG COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
PKFBPKFJ_01644	457412.RSAG_01431	2.03e-190	530.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,3WGFX@541000|Ruminococcaceae	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
PKFBPKFJ_01645	1121115.AXVN01000010_gene2778	1.26e-192	537.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,3XYWM@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
PKFBPKFJ_01646	1121115.AXVN01000010_gene2779	2.49e-179	499.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3XYGV@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
PKFBPKFJ_01647	1121115.AXVN01000010_gene2780	1.05e-152	429.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,3XZTS@572511|Blautia	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
PKFBPKFJ_01648	1121115.AXVN01000010_gene2781	0.0	1041.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZMN@572511|Blautia	186801|Clostridia	T	Single Cache-like	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
PKFBPKFJ_01649	457412.RSAG_01426	0.0	1035.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UCUQ@1239|Firmicutes,24FD5@186801|Clostridia,3WPDP@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
PKFBPKFJ_01650	457412.RSAG_01425	0.0	1104.0	COG2972@1|root,COG2972@2|Bacteria,1U6WN@1239|Firmicutes,24CTB@186801|Clostridia,3WJZ8@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
PKFBPKFJ_01651	1121115.AXVN01000010_gene2784	0.0	968.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,25NJ2@186801|Clostridia,3Y1EP@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3502
PKFBPKFJ_01652	457412.RSAG_01423	4.24e-216	596.0	COG4209@1|root,COG4209@2|Bacteria,1TQFY@1239|Firmicutes,24923@186801|Clostridia,3WGA3@541000|Ruminococcaceae	186801|Clostridia	U	ABC-type polysaccharide transport system permease component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
PKFBPKFJ_01653	1121115.AXVN01000010_gene2786	2.5e-201	558.0	COG0395@1|root,COG0395@2|Bacteria,1TP1G@1239|Firmicutes,247T2@186801|Clostridia,3Y1FV@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_01654	457412.RSAG_01421	0.0	1832.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3WGRC@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PKFBPKFJ_01655	457412.RSAG_01420	3.13e-133	377.0	COG1309@1|root,COG1309@2|Bacteria,1V73E@1239|Firmicutes,25B5N@186801|Clostridia,3WJEZ@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PKFBPKFJ_01656	1121115.AXVN01000010_gene2789	1.64e-123	353.0	COG3247@1|root,COG3247@2|Bacteria,1VFKP@1239|Firmicutes,24RBX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
PKFBPKFJ_01657	457412.RSAG_01418	0.0	938.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3WH2D@541000|Ruminococcaceae	186801|Clostridia	C	Radical SAM domain protein	atsB	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
PKFBPKFJ_01658	457412.RSAG_01417	0.0	1064.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3WISK@541000|Ruminococcaceae	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
PKFBPKFJ_01659	457412.RSAG_01416	0.0	915.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3WGJF@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
PKFBPKFJ_01660	1121115.AXVN01000010_gene2793	4.22e-244	671.0	COG1879@1|root,COG1879@2|Bacteria,1TQ1B@1239|Firmicutes,247K8@186801|Clostridia,3Y1DY@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K02058	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	Peripla_BP_4
PKFBPKFJ_01661	457412.RSAG_01414	0.0	980.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3WH2F@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system, ATPase component	araG_1	-	3.6.3.17	ko:K02056,ko:K10441	ko02010,map02010	M00212,M00221	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
PKFBPKFJ_01662	1121115.AXVN01000010_gene2795	7.39e-233	643.0	COG1172@1|root,COG1172@2|Bacteria,1TR6F@1239|Firmicutes,2484T@186801|Clostridia,3Y10U@572511|Blautia	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	ytfT	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
PKFBPKFJ_01663	1121115.AXVN01000010_gene2796	4.59e-226	625.0	COG1172@1|root,COG1172@2|Bacteria,1TPPT@1239|Firmicutes,248FJ@186801|Clostridia,3Y1F9@572511|Blautia	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	yjfF	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
PKFBPKFJ_01664	457412.RSAG_01411	1.18e-223	614.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,3WGYH@541000|Ruminococcaceae	186801|Clostridia	J	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
PKFBPKFJ_01665	457412.RSAG_01410	5.51e-205	567.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,248B1@186801|Clostridia,3WGRW@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
PKFBPKFJ_01666	457412.RSAG_04514	5.14e-42	137.0	2CA4K@1|root,347XV@2|Bacteria,1VZ7Z@1239|Firmicutes,253MY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01667	1121115.AXVN01000010_gene2800	2.83e-210	582.0	2DS3C@1|root,33EBY@2|Bacteria,1U8VV@1239|Firmicutes,24EGD@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2971
PKFBPKFJ_01668	457412.RSAG_01408	6.6e-295	808.0	COG4632@1|root,COG5263@1|root,COG4632@2|Bacteria,COG5263@2|Bacteria,1TR6Z@1239|Firmicutes,25B3H@186801|Clostridia,3WJIW@541000|Ruminococcaceae	186801|Clostridia	G	Phosphodiester glycosidase	-	-	-	-	-	-	-	-	-	-	-	-	NAGPA
PKFBPKFJ_01669	1121115.AXVN01000010_gene2802	7.51e-23	87.8	2CA4N@1|root,2ZQ5H@2|Bacteria,1W5T5@1239|Firmicutes,256DT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01670	1121115.AXVN01000010_gene2804	9.69e-317	861.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,3XZB7@572511|Blautia	186801|Clostridia	EK	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
PKFBPKFJ_01671	457412.RSAG_01405	0.0	912.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3WIPN@541000|Ruminococcaceae	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
PKFBPKFJ_01672	457412.RSAG_01404	1.33e-255	700.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3WGGM@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
PKFBPKFJ_01673	457412.RSAG_01403	0.0	902.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3WH5M@541000|Ruminococcaceae	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PKFBPKFJ_01674	1121115.AXVN01000010_gene2808	1.85e-136	386.0	2EXAI@1|root,33QM6@2|Bacteria,1VU0R@1239|Firmicutes,24YTY@186801|Clostridia,3Y0G1@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01675	1121115.AXVN01000010_gene2809	2.97e-63	192.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia,3Y0DQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01676	1121115.AXVN01000037_gene3266	0.0	1495.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3XYPZ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	ybhJ	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
PKFBPKFJ_01677	457412.RSAG_01390	1.57e-168	470.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,3WHF8@541000|Ruminococcaceae	186801|Clostridia	J	Pseudouridine synthase	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
PKFBPKFJ_01678	1121115.AXVN01000037_gene3264	1.06e-257	707.0	COG1879@1|root,COG1879@2|Bacteria,1UZFA@1239|Firmicutes,249QV@186801|Clostridia,3XYTX@572511|Blautia	186801|Clostridia	G	COG COG1879 ABC-type sugar transport system, periplasmic component	rbsB_4	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
PKFBPKFJ_01679	1121115.AXVN01000037_gene3263	2.9e-56	175.0	2EC1A@1|root,3360H@2|Bacteria,1VHMT@1239|Firmicutes,24S6Y@186801|Clostridia,3Y1SK@572511|Blautia	186801|Clostridia	S	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter	-	-	-	-	-	-	-	-	-	-	-	-	ATPase_gene1
PKFBPKFJ_01680	1121115.AXVN01000037_gene3262	7.79e-93	271.0	2BAXA@1|root,324CZ@2|Bacteria,1UQP9@1239|Firmicutes,258FM@186801|Clostridia,3Y1K7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01681	457412.RSAG_04512	1.81e-172	482.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6A@186801|Clostridia,3WIKS@541000|Ruminococcaceae	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
PKFBPKFJ_01682	1121115.AXVN01000037_gene3260	1.25e-56	176.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3Y1RW@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
PKFBPKFJ_01683	1121115.AXVN01000037_gene3259	1.94e-91	270.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,258VV@186801|Clostridia,3Y0ZV@572511|Blautia	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_B
PKFBPKFJ_01684	457412.RSAG_01381	1.82e-120	344.0	COG0712@1|root,COG0712@2|Bacteria,1VAG3@1239|Firmicutes,24JWN@186801|Clostridia,3WS23@541000|Ruminococcaceae	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
PKFBPKFJ_01685	1121115.AXVN01000037_gene3257	0.0	978.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3Y1A3@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
PKFBPKFJ_01686	1121115.AXVN01000037_gene3256	7.72e-195	541.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3Y0ZD@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
PKFBPKFJ_01687	1121115.AXVN01000037_gene3255	0.0	909.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3Y1D7@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
PKFBPKFJ_01688	1121115.AXVN01000037_gene3254	1.73e-89	262.0	COG0355@1|root,COG0355@2|Bacteria,1TTR7@1239|Firmicutes,25MVC@186801|Clostridia,3Y1KM@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	-	-	-	-	-	-	-	-	-	-	-	-	ATP-synt_DE,ATP-synt_DE_N
PKFBPKFJ_01689	457412.RSAG_01375	1.02e-42	139.0	29UA8@1|root,3489I@2|Bacteria,1VZGI@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01690	457412.RSAG_01374	5.75e-147	413.0	COG0500@1|root,COG2226@2|Bacteria,1TVU2@1239|Firmicutes,24AIJ@186801|Clostridia,3WJ6T@541000|Ruminococcaceae	186801|Clostridia	Q	Methyltransferase domain protein	-	-	-	ko:K15256	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
PKFBPKFJ_01691	1256908.HMPREF0373_01256	3.22e-53	166.0	2AD7W@1|root,312WU@2|Bacteria,1V7M4@1239|Firmicutes,25D70@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01692	1256908.HMPREF0373_01255	0.0	1384.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,25Y8P@186806|Eubacteriaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PKFBPKFJ_01693	1256908.HMPREF0373_01254	5.21e-178	496.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_01694	1256908.HMPREF0373_01253	1.76e-233	643.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,25ZV2@186806|Eubacteriaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
PKFBPKFJ_01695	1256908.HMPREF0373_01252	3.69e-157	441.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,25V3T@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_01696	457412.RSAG_04767	0.0	1125.0	COG2433@1|root,COG2433@2|Bacteria,1UI5D@1239|Firmicutes,25EHI@186801|Clostridia,3WSS3@541000|Ruminococcaceae	186801|Clostridia	S	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PKFBPKFJ_01697	457412.RSAG_04766	1.72e-82	244.0	2DM3V@1|root,31MG3@2|Bacteria,1V9H1@1239|Firmicutes,24MF4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01698	457412.RSAG_02978	1.13e-60	187.0	28NQR@1|root,2ZBQ4@2|Bacteria,1V3BU@1239|Firmicutes,24FVP@186801|Clostridia,3WPFF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01699	397290.C810_01656	1.35e-46	149.0	2DAN3@1|root,32TVS@2|Bacteria,1VABD@1239|Firmicutes,24N3S@186801|Clostridia,27NRT@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PKFBPKFJ_01700	411489.CLOL250_01810	1.34e-139	395.0	COG1396@1|root,COG1396@2|Bacteria,1TRKK@1239|Firmicutes,24TBF@186801|Clostridia,36P0Q@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_01701	457412.RSAG_02981	2.81e-314	855.0	COG0582@1|root,COG0582@2|Bacteria,1TSQW@1239|Firmicutes,249T6@186801|Clostridia,3WHU5@541000|Ruminococcaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_01702	457412.RSAG_02207	1.2e-283	775.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,3WH96@541000|Ruminococcaceae	186801|Clostridia	E	PFAM Aminotransferase class I and II	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
PKFBPKFJ_01703	457412.RSAG_02208	1.03e-315	860.0	COG1070@1|root,COG1070@2|Bacteria,1TSEJ@1239|Firmicutes,24AT3@186801|Clostridia,3WN88@541000|Ruminococcaceae	186801|Clostridia	G	FGGY family of carbohydrate kinases, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
PKFBPKFJ_01704	1121115.AXVN01000037_gene3251	0.0	1132.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3Y19R@572511|Blautia	186801|Clostridia	P	Na+/Pi-cotransporter	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
PKFBPKFJ_01705	457412.RSAG_02210	6.79e-55	171.0	2DWC0@1|root,33ZIT@2|Bacteria,1VY40@1239|Firmicutes,252ED@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01706	457412.RSAG_02211	2.34e-239	657.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3WM8X@541000|Ruminococcaceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
PKFBPKFJ_01707	457412.RSAG_02212	1.38e-273	748.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia,3WICI@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
PKFBPKFJ_01708	1121115.AXVN01000037_gene3247	0.0	1062.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3XYQY@572511|Blautia	186801|Clostridia	G	Mannitol dehydrogenase Rossmann domain	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
PKFBPKFJ_01709	1121115.AXVN01000037_gene3246	2.88e-17	75.9	COG0346@1|root,COG0346@2|Bacteria,1V7XP@1239|Firmicutes,24KYI@186801|Clostridia,3Y0HK@572511|Blautia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
PKFBPKFJ_01710	1121115.AXVN01000037_gene3245	7.92e-81	240.0	2CFUE@1|root,33V7A@2|Bacteria,1VUR9@1239|Firmicutes,250BS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01711	457412.RSAG_02215	4.53e-117	335.0	COG0716@1|root,COG0716@2|Bacteria,1VB6B@1239|Firmicutes,24GQN@186801|Clostridia,3WIVQ@541000|Ruminococcaceae	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
PKFBPKFJ_01712	1121115.AXVN01000037_gene3243	7.62e-248	681.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,3XZQ0@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
PKFBPKFJ_01713	1121115.AXVN01000037_gene3242	2.08e-305	837.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3Y0X8@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
PKFBPKFJ_01714	1121115.AXVN01000037_gene3241	3.65e-256	703.0	COG3347@1|root,COG3347@2|Bacteria,1TQB8@1239|Firmicutes,25BHR@186801|Clostridia,3Y16D@572511|Blautia	186801|Clostridia	IQ	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
PKFBPKFJ_01715	1121115.AXVN01000037_gene3240	0.0	1727.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
PKFBPKFJ_01716	1121115.AXVN01000037_gene3239	0.0	1182.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3XYY0@572511|Blautia	186801|Clostridia	T	GTP-binding protein TypA BipA homolog	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
PKFBPKFJ_01717	1121115.AXVN01000037_gene3238	1.25e-148	418.0	COG0629@1|root,COG0629@2|Bacteria,1TRWZ@1239|Firmicutes,248UD@186801|Clostridia,3XZI3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ssb1	-	-	-	-	-	-	-	-	-	-	-	SSB
PKFBPKFJ_01718	1121115.AXVN01000125_gene3804	2.1e-109	315.0	COG2109@1|root,COG2109@2|Bacteria,1V82Z@1239|Firmicutes,24J8J@186801|Clostridia,3Y0A2@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
PKFBPKFJ_01719	1121115.AXVN01000125_gene3805	1.52e-207	574.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3XZIM@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
PKFBPKFJ_01720	1121115.AXVN01000125_gene3806	1.05e-176	493.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,3XZD1@572511|Blautia	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
PKFBPKFJ_01721	457412.RSAG_02225	5.62e-292	798.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WGET@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
PKFBPKFJ_01722	1121115.AXVN01000125_gene3808	2.32e-28	110.0	2EYMV@1|root,33RVF@2|Bacteria,1VSPB@1239|Firmicutes,24XPM@186801|Clostridia,3Y0UE@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01723	1121115.AXVN01000125_gene3809	4.33e-186	516.0	COG0106@1|root,COG0106@2|Bacteria,1TPIN@1239|Firmicutes,249HJ@186801|Clostridia,3XYK1@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisA	-	-	-	-	-	-	-	-	-	-	-	His_biosynth
PKFBPKFJ_01724	1121115.AXVN01000125_gene3810	6.26e-118	338.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3XZRY@572511|Blautia	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
PKFBPKFJ_01725	1121115.AXVN01000125_gene3811	0.0	1014.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3XYYI@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
PKFBPKFJ_01726	1121115.AXVN01000028_gene192	0.0	1658.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3XYPH@572511|Blautia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
PKFBPKFJ_01727	457412.RSAG_02232	0.0	967.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3WHBC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
PKFBPKFJ_01728	457412.RSAG_02233	1.52e-206	571.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ8Y@1239|Firmicutes,248SM@186801|Clostridia,3WJQB@541000|Ruminococcaceae	186801|Clostridia	K	PFAM AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PKFBPKFJ_01729	1121115.AXVN01000028_gene195	3.17e-202	560.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24B81@186801|Clostridia,3XZ57@572511|Blautia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF_2	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
PKFBPKFJ_01730	1121115.AXVN01000028_gene197	3.29e-234	644.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,3XZ5R@572511|Blautia	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
PKFBPKFJ_01731	1121115.AXVN01000028_gene198	3.59e-102	296.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,3XZTJ@572511|Blautia	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
PKFBPKFJ_01732	457412.RSAG_02237	4.09e-291	795.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3WGG4@541000|Ruminococcaceae	186801|Clostridia	E	homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
PKFBPKFJ_01733	1121115.AXVN01000028_gene200	5.71e-281	769.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3XYJN@572511|Blautia	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
PKFBPKFJ_01734	1121115.AXVN01000028_gene201	5.06e-240	662.0	COG5523@1|root,COG5523@2|Bacteria,1VGYA@1239|Firmicutes,24SD1@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
PKFBPKFJ_01735	1121115.AXVN01000028_gene202	8.12e-300	818.0	COG2234@1|root,COG2234@2|Bacteria,1UFM1@1239|Firmicutes	1239|Firmicutes	S	Aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
PKFBPKFJ_01736	457412.RSAG_02241	0.0	1370.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,3WGWI@541000|Ruminococcaceae	186801|Clostridia	K	Tex-like protein N-terminal domain	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
PKFBPKFJ_01737	1121115.AXVN01000028_gene204	2.01e-212	587.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3XZVT@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_01738	457412.RSAG_02243	3.56e-47	151.0	COG1925@1|root,COG1925@2|Bacteria,1VWWX@1239|Firmicutes,252H5@186801|Clostridia	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01739	457412.RSAG_02244	2.02e-62	191.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,3WKTD@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1294)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
PKFBPKFJ_01740	457412.RSAG_02245	4.31e-197	547.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,3WHGA@541000|Ruminococcaceae	186801|Clostridia	M	Mechanosensitive ion channel	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
PKFBPKFJ_01741	457412.RSAG_02246	0.0	1066.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3WISX@541000|Ruminococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035,ko:K13889	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	SBP_bac_5
PKFBPKFJ_01742	1121115.AXVN01000028_gene209	1.76e-206	572.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3Y02S@572511|Blautia	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K13890	ko02010,map02010	M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.11	-	-	BPD_transp_1
PKFBPKFJ_01743	457412.RSAG_02248	9.03e-185	517.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WJDM@541000|Ruminococcaceae	186801|Clostridia	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034,ko:K13891	ko02010,ko02024,map02010,map02024	M00239,M00348	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.11	-	-	BPD_transp_1,OppC_N
PKFBPKFJ_01744	457412.RSAG_02249	2.42e-236	650.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WGTC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	oppD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PKFBPKFJ_01745	457412.RSAG_04635	1.99e-237	652.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WH83@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
PKFBPKFJ_01746	457412.RSAG_02250	1.27e-176	493.0	COG1349@1|root,COG1349@2|Bacteria,1TSU1@1239|Firmicutes,25C4E@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, DeoR	-	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
PKFBPKFJ_01747	457412.RSAG_02251	1.44e-176	492.0	COG3142@1|root,COG3142@2|Bacteria,1UYI8@1239|Firmicutes,247QB@186801|Clostridia,3WIQQ@541000|Ruminococcaceae	186801|Clostridia	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
PKFBPKFJ_01748	1121115.AXVN01000028_gene215	0.0	1648.0	COG1305@1|root,COG1305@2|Bacteria,1TQGN@1239|Firmicutes,249YH@186801|Clostridia,3Y18M@572511|Blautia	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PKFBPKFJ_01749	457412.RSAG_02253	0.0	942.0	COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,24B8Y@186801|Clostridia,3WNMV@541000|Ruminococcaceae	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
PKFBPKFJ_01750	457412.RSAG_02254	3.58e-119	340.0	COG0614@1|root,COG0614@2|Bacteria,1UK9K@1239|Firmicutes,25FRK@186801|Clostridia,3WJHV@541000|Ruminococcaceae	186801|Clostridia	HP	small periplasmic lipoprotein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01751	457412.RSAG_02255	7.15e-164	458.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,249DM@186801|Clostridia,3WIU3@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-2 C20-methyltransferase	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
PKFBPKFJ_01752	457412.RSAG_02256	1.5e-194	540.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,3WJGT@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	nodI	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
PKFBPKFJ_01753	457412.RSAG_02257	4.48e-173	483.0	COG0842@1|root,COG0842@2|Bacteria,1UYEB@1239|Firmicutes,24BUQ@186801|Clostridia,3WMU4@541000|Ruminococcaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
PKFBPKFJ_01754	1121115.AXVN01000028_gene221	0.0	1796.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Peptidase_S51,Response_reg
PKFBPKFJ_01755	457412.RSAG_02260	2e-208	577.0	COG0583@1|root,COG0583@2|Bacteria,1TSA6@1239|Firmicutes,24BM8@186801|Clostridia,3WRR9@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	cmpR	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_01756	457412.RSAG_02261	7.71e-276	754.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,3WH06@541000|Ruminococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	csd	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
PKFBPKFJ_01757	457412.RSAG_02262	1.94e-91	267.0	COG1943@1|root,COG1943@2|Bacteria,1V5MU@1239|Firmicutes,24HFH@186801|Clostridia	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
PKFBPKFJ_01758	457412.RSAG_02263	8.68e-278	759.0	COG0675@1|root,COG0675@2|Bacteria,1TT4J@1239|Firmicutes,24CV7@186801|Clostridia,3WR4V@541000|Ruminococcaceae	186801|Clostridia	L	Putative transposase DNA-binding domain	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
PKFBPKFJ_01759	457412.RSAG_02264	6.56e-252	692.0	COG2391@1|root,COG2391@2|Bacteria,1TPWG@1239|Firmicutes,249KU@186801|Clostridia,3WIA9@541000|Ruminococcaceae	186801|Clostridia	S	Sulphur transport	-	-	-	ko:K07112	-	-	-	-	ko00000	-	-	-	Sulf_transp
PKFBPKFJ_01760	457412.RSAG_02307	3.38e-56	176.0	2BQ4H@1|root,32IYV@2|Bacteria,1US27@1239|Firmicutes,25A0K@186801|Clostridia,3WQZK@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01761	1121115.AXVN01000131_gene738	1.55e-179	501.0	2E509@1|root,32ZTU@2|Bacteria,1VB4U@1239|Firmicutes,249Y2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01762	457412.RSAG_02305	8.3e-117	335.0	COG1595@1|root,COG1595@2|Bacteria,1VGKP@1239|Firmicutes,24RUX@186801|Clostridia,3WKQD@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_01763	457412.RSAG_02304	8.27e-105	302.0	COG1661@1|root,COG1661@2|Bacteria,1VBWE@1239|Firmicutes,24HQ2@186801|Clostridia,3WMN1@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
PKFBPKFJ_01764	1121115.AXVN01000038_gene3345	1.8e-222	614.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,25D2S@186801|Clostridia,3Y1VG@572511|Blautia	186801|Clostridia	K	Putative sugar-binding domain	sorC	-	-	-	-	-	-	-	-	-	-	-	HTH_24,Sugar-bind
PKFBPKFJ_01765	1121115.AXVN01000038_gene3344	3.17e-172	479.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,3XYMH@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	ulaF	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
PKFBPKFJ_01766	1121115.AXVN01000038_gene3343	4.65e-263	719.0	28IPH@1|root,2Z8PG@2|Bacteria,1TREB@1239|Firmicutes,248QM@186801|Clostridia,3Y18D@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01767	1121115.AXVN01000038_gene3342	0.0	895.0	COG3037@1|root,COG3037@2|Bacteria,1TQK5@1239|Firmicutes,247MD@186801|Clostridia,3Y0FE@572511|Blautia	186801|Clostridia	S	PTS system sugar-specific permease component	-	-	-	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	M00283,M00550	R07671	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.7.1	-	-	EIIC-GAT
PKFBPKFJ_01768	1121115.AXVN01000038_gene3341	0.0	1009.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XZDA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.17,2.7.1.30	ko:K00854,ko:K00864	ko00040,ko00561,ko01100,ko03320,ko04626,map00040,map00561,map01100,map03320,map04626	M00014	R00847,R01639	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
PKFBPKFJ_01769	1121115.AXVN01000038_gene3340	2.15e-290	790.0	COG2220@1|root,COG2220@2|Bacteria,1TSFV@1239|Firmicutes,249MG@186801|Clostridia,3Y1A5@572511|Blautia	186801|Clostridia	S	Beta-lactamase superfamily domain	ulaG	-	-	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	M00550	R07677	RC02793	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactamase_B_2,Lactamase_B_3
PKFBPKFJ_01770	1121115.AXVN01000038_gene3339	2.34e-203	562.0	COG3623@1|root,COG3623@2|Bacteria,1TSMS@1239|Firmicutes,247T6@186801|Clostridia,3Y1CM@572511|Blautia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	ulaE	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
PKFBPKFJ_01771	1121115.AXVN01000038_gene3338	3.46e-91	266.0	2E2GC@1|root,32XKF@2|Bacteria,1VCKF@1239|Firmicutes,24QFN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01772	1121115.AXVN01000038_gene3337	1.48e-175	490.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,3XYRK@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	gufA	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
PKFBPKFJ_01773	457412.RSAG_02302	2.19e-96	280.0	COG4357@1|root,COG4357@2|Bacteria,1VB64@1239|Firmicutes,24ZZZ@186801|Clostridia	186801|Clostridia	S	CHY zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHY
PKFBPKFJ_01774	1121115.AXVN01000038_gene3335	1.35e-127	363.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,3Y025@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
PKFBPKFJ_01775	1121115.AXVN01000038_gene3334	0.0	964.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V2J2@1239|Firmicutes,24CQK@186801|Clostridia,3Y1VC@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
PKFBPKFJ_01776	1121115.AXVN01000038_gene3333	0.0	1119.0	COG2972@1|root,COG2972@2|Bacteria,1UZWA@1239|Firmicutes,24EGG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
PKFBPKFJ_01777	1121115.AXVN01000038_gene3332	7.71e-192	533.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia,3XZGR@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PKFBPKFJ_01778	457412.RSAG_02297	3.55e-204	566.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,3WKCR@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PKFBPKFJ_01779	1121115.AXVN01000038_gene3330	2.03e-291	797.0	COG2182@1|root,COG2182@2|Bacteria,1V961@1239|Firmicutes,24MCD@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01780	1121115.AXVN01000038_gene3329	1.16e-285	780.0	COG0673@1|root,COG0673@2|Bacteria,1V0MQ@1239|Firmicutes,24CZ7@186801|Clostridia,3XZSH@572511|Blautia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
PKFBPKFJ_01781	1121115.AXVN01000038_gene3328	0.0	1119.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PKFBPKFJ_01782	1121115.AXVN01000038_gene3327	4.8e-273	749.0	COG2184@1|root,COG2184@2|Bacteria,1TNY6@1239|Firmicutes,249XE@186801|Clostridia,3XZES@572511|Blautia	186801|Clostridia	D	COG COG2184 Protein involved in cell division	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_24
PKFBPKFJ_01783	1121115.AXVN01000038_gene3326	1.76e-194	539.0	COG0566@1|root,COG0566@2|Bacteria,1TSUW@1239|Firmicutes,24ACK@186801|Clostridia,3XYTE@572511|Blautia	186801|Clostridia	H	SpoU rRNA Methylase family	-	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
PKFBPKFJ_01784	457412.RSAG_02287	4.62e-293	802.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia,3WH7U@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_01785	457412.RSAG_02286	0.0	903.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3WHVA@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	gph	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2
PKFBPKFJ_01786	457412.RSAG_02285	2.29e-252	691.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,3WI2M@541000|Ruminococcaceae	186801|Clostridia	C	COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
PKFBPKFJ_01787	457412.RSAG_02284	9.16e-264	723.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia,3WH5F@541000|Ruminococcaceae	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
PKFBPKFJ_01788	1121115.AXVN01000038_gene3321	4.22e-303	828.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,2481G@186801|Clostridia,3XYVW@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_01789	1121115.AXVN01000038_gene3319	3.69e-33	114.0	2FJZK@1|root,34BMY@2|Bacteria,1VZAP@1239|Firmicutes,2533H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01790	457412.RSAG_02280	0.0	1612.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3WGRC@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PKFBPKFJ_01791	457412.RSAG_02279	1.64e-142	402.0	COG0494@1|root,COG0494@2|Bacteria,1V27D@1239|Firmicutes,24GB6@186801|Clostridia,3WRQY@541000|Ruminococcaceae	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
PKFBPKFJ_01792	1121115.AXVN01000038_gene3316	1.33e-91	267.0	COG1669@1|root,COG1669@2|Bacteria,1U3WZ@1239|Firmicutes,25933@186801|Clostridia,3Y22N@572511|Blautia	186801|Clostridia	S	Nucleotidyltransferase substrate binding protein like	-	-	-	-	-	-	-	-	-	-	-	-	NTase_sub_bind
PKFBPKFJ_01793	1121115.AXVN01000038_gene3315	1.94e-60	186.0	COG1669@1|root,COG1669@2|Bacteria,1VEWI@1239|Firmicutes,25DNH@186801|Clostridia,3Y1WZ@572511|Blautia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
PKFBPKFJ_01794	457412.RSAG_02276	1.1e-139	395.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,3WI1Y@541000|Ruminococcaceae	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
PKFBPKFJ_01795	457412.RSAG_02275	8.86e-133	377.0	2EJGK@1|root,33D7H@2|Bacteria,1VMPJ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01798	457412.RSAG_02272	1.2e-90	266.0	2DNMV@1|root,32Y6A@2|Bacteria,1VFC4@1239|Firmicutes,24QMI@186801|Clostridia,3WMGA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01799	1121115.AXVN01000175_gene3963	1.67e-217	601.0	COG3103@1|root,COG3103@2|Bacteria,1VAHD@1239|Firmicutes,24NRJ@186801|Clostridia,3Y237@572511|Blautia	186801|Clostridia	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
PKFBPKFJ_01800	742733.HMPREF9469_02841	9.93e-121	355.0	COG0679@1|root,COG0679@2|Bacteria,1V0ZS@1239|Firmicutes,24CQ0@186801|Clostridia,21ZFT@1506553|Lachnoclostridium	186801|Clostridia	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
PKFBPKFJ_01801	1235798.C817_01006	1.34e-12	67.8	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,27WK3@189330|Dorea	186801|Clostridia	E	DNA polymerase alpha chain like domain	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
PKFBPKFJ_01802	1232452.BAIB02000020_gene2685	2.32e-25	103.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,24ET5@186801|Clostridia	186801|Clostridia	K	cog cog2390	-	-	-	-	-	-	-	-	-	-	-	-	Sugar-bind
PKFBPKFJ_01803	1121115.AXVN01000028_gene226	3.46e-53	166.0	2DKC3@1|root,30954@2|Bacteria,1U4FV@1239|Firmicutes,258BV@186801|Clostridia,3Y1WH@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
PKFBPKFJ_01804	1121115.AXVN01000028_gene225	6.9e-41	134.0	COG0425@1|root,COG0425@2|Bacteria,1VKDK@1239|Firmicutes,24RK7@186801|Clostridia,3Y1ZM@572511|Blautia	186801|Clostridia	O	Sulfurtransferase TusA	-	-	-	-	-	-	-	-	-	-	-	-	TusA
PKFBPKFJ_01805	457412.RSAG_01324	8.67e-146	419.0	COG0675@1|root,COG0675@2|Bacteria,1TQAH@1239|Firmicutes,24EGY@186801|Clostridia	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	OrfB_IS605,OrfB_Zn_ribbon
PKFBPKFJ_01806	1121115.AXVN01000009_gene1471	0.0	1742.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia	186801|Clostridia	G	Phosphoenolpyruvate synthase pyruvate phosphate dikinase	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
PKFBPKFJ_01807	1121115.AXVN01000009_gene1470	1.11e-302	825.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3XZA1@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
PKFBPKFJ_01808	1121115.AXVN01000009_gene1469	1.13e-224	617.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,3XZNJ@572511|Blautia	186801|Clostridia	G	COG COG2017 Galactose mutarotase and related enzymes	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
PKFBPKFJ_01809	1121115.AXVN01000009_gene1468	8.48e-203	562.0	COG0646@1|root,COG0646@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3XZSY@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
PKFBPKFJ_01810	1121115.AXVN01000009_gene1467	6.24e-267	731.0	COG1146@1|root,COG2006@1|root,COG1146@2|Bacteria,COG2006@2|Bacteria,1TRX2@1239|Firmicutes,249GX@186801|Clostridia,3XZST@572511|Blautia	186801|Clostridia	C	Domain of unknown function (DUF362)	-	-	-	-	-	-	-	-	-	-	-	-	DUF362,Fer4,Fer4_10,Fer4_7
PKFBPKFJ_01811	1121115.AXVN01000009_gene1466	0.0	1053.0	COG1080@1|root,COG1080@2|Bacteria,1VRHN@1239|Firmicutes,24YXY@186801|Clostridia,3XZB5@572511|Blautia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	-	-	-	-	-	-	-	-	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
PKFBPKFJ_01812	1121115.AXVN01000009_gene1465	1.42e-247	679.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3XZJT@572511|Blautia	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
PKFBPKFJ_01813	457412.RSAG_00343	0.0	1147.0	COG0687@1|root,COG1177@1|root,COG0687@2|Bacteria,COG1177@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3WHCV@541000|Ruminococcaceae	186801|Clostridia	P	Spermidine putrescine-binding periplasmic protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
PKFBPKFJ_01814	1121115.AXVN01000009_gene1463	7.09e-184	512.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,3XYI0@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
PKFBPKFJ_01815	457412.RSAG_00345	7.08e-250	686.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGI6@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
PKFBPKFJ_01816	1121115.AXVN01000009_gene1461	4.4e-171	479.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,3XZ3R@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	iHN637.CLJU_RS10670	BPD_transp_1
PKFBPKFJ_01817	1121115.AXVN01000009_gene1460	1.56e-195	543.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,24F3Z@186801|Clostridia,3XZMZ@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
PKFBPKFJ_01818	457412.RSAG_00348	3.9e-269	739.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WGI6@541000|Ruminococcaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
PKFBPKFJ_01820	1121115.AXVN01000009_gene1457	0.0	1516.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3XZ76@572511|Blautia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
PKFBPKFJ_01821	1121115.AXVN01000009_gene1456	2.71e-235	647.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3XYNT@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
PKFBPKFJ_01822	457412.RSAG_00353	1.62e-277	759.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,3WGQB@541000|Ruminococcaceae	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PKFBPKFJ_01823	1121115.AXVN01000004_gene1926	1.4e-262	719.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3XZDW@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
PKFBPKFJ_01824	457412.RSAG_00355	0.0	1106.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3WHFZ@541000|Ruminococcaceae	186801|Clostridia	H	acetolactate synthase large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PKFBPKFJ_01825	1121115.AXVN01000004_gene1928	0.0	1098.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3XYR1@572511|Blautia	186801|Clostridia	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PKFBPKFJ_01826	1121115.AXVN01000004_gene1929	4.82e-254	697.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3XZ5D@572511|Blautia	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
PKFBPKFJ_01827	1121115.AXVN01000004_gene1930	8.14e-63	192.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3Y0GK@572511|Blautia	186801|Clostridia	U	COG COG1862 Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
PKFBPKFJ_01828	1121115.AXVN01000004_gene1932	2.08e-287	783.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,3XZ2I@572511|Blautia	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
PKFBPKFJ_01829	457412.RSAG_00361	0.0	2799.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,3WGW6@541000|Ruminococcaceae	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
PKFBPKFJ_01830	457412.RSAG_00362	0.0	1009.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3WH0Z@541000|Ruminococcaceae	186801|Clostridia	S	Polysaccharide biosynthesis protein	spoVB1	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
PKFBPKFJ_01831	1121115.AXVN01000004_gene1935	4.9e-172	478.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia,3XYSN@572511|Blautia	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
PKFBPKFJ_01832	1121115.AXVN01000004_gene1936	6.86e-177	493.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,3XZ31@572511|Blautia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
PKFBPKFJ_01833	457412.RSAG_00365	1.58e-153	431.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,3WGIA@541000|Ruminococcaceae	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
PKFBPKFJ_01834	1410630.JNKP01000003_gene1018	3.92e-63	215.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,27IJX@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
PKFBPKFJ_01837	1243664.CAVL020000010_gene4521	2.09e-54	193.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,4H9U4@91061|Bacilli,1ZANE@1386|Bacillus	1239|Firmicutes	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	-	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small
PKFBPKFJ_01838	457412.RSAG_00263	6.85e-157	440.0	28HI8@1|root,2Z9QV@2|Bacteria,1UZZ2@1239|Firmicutes,24IH2@186801|Clostridia,3WJDW@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
PKFBPKFJ_01839	457412.RSAG_00255	6.27e-142	400.0	COG2818@1|root,COG2818@2|Bacteria,1UYWG@1239|Firmicutes,249EP@186801|Clostridia,3WI1J@541000|Ruminococcaceae	186801|Clostridia	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
PKFBPKFJ_01840	457412.RSAG_00254	3.16e-158	443.0	COG1787@1|root,COG1787@2|Bacteria,1VBYF@1239|Firmicutes,24R49@186801|Clostridia,3WKV5@541000|Ruminococcaceae	186801|Clostridia	V	Restriction endonuclease	-	-	-	ko:K07448	-	-	-	-	ko00000,ko02048	-	-	-	Ftsk_gamma,Mrr_cat,zf-C4_Topoisom
PKFBPKFJ_01841	457412.RSAG_00253	1e-166	467.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,3WIP0@541000|Ruminococcaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
PKFBPKFJ_01842	457412.RSAG_00252	0.0	923.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,3WHMF@541000|Ruminococcaceae	186801|Clostridia	C	Aldehyde dehydrogenase	ywdH	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
PKFBPKFJ_01843	457412.RSAG_00251	1.81e-293	801.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,249X1@186801|Clostridia,3WJCU@541000|Ruminococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
PKFBPKFJ_01844	1121115.AXVN01000017_gene266	7.35e-22	90.5	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3Y11K@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_01845	1121115.AXVN01000007_gene3532	3.63e-250	688.0	COG3935@1|root,COG3935@2|Bacteria,1VCAM@1239|Firmicutes,24E45@186801|Clostridia	186801|Clostridia	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01846	1121115.AXVN01000007_gene3533	5.4e-118	338.0	2ESEK@1|root,33JZA@2|Bacteria,1VNHH@1239|Firmicutes,24UXF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01847	1121115.AXVN01000007_gene3534	1.13e-218	603.0	2DB8G@1|root,2Z7RT@2|Bacteria,1US26@1239|Firmicutes,24B9G@186801|Clostridia,3Y166@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01848	1121115.AXVN01000007_gene3535	2.21e-88	260.0	2EZBW@1|root,33SH8@2|Bacteria,1VS1Y@1239|Firmicutes,24YDS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01850	1121115.AXVN01000007_gene3537	0.0	3388.0	COG4932@1|root,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,2492K@186801|Clostridia,3XZ4G@572511|Blautia	186801|Clostridia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01851	1121115.AXVN01000007_gene3538	3.81e-67	203.0	2DBK7@1|root,2Z9RA@2|Bacteria,1UC8U@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4313
PKFBPKFJ_01852	1121115.AXVN01000007_gene3539	3.31e-267	731.0	COG1032@1|root,COG1032@2|Bacteria,1TRY3@1239|Firmicutes,249Q1@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01853	1121115.AXVN01000007_gene3540	3.12e-251	689.0	COG0358@1|root,COG0358@2|Bacteria,1TQTJ@1239|Firmicutes,25C9F@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3991,Toprim_2
PKFBPKFJ_01855	1121115.AXVN01000007_gene3542	2.17e-126	372.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,3Y0XY@572511|Blautia	186801|Clostridia	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
PKFBPKFJ_01856	1121115.AXVN01000007_gene3542	2.25e-214	600.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,3Y0XY@572511|Blautia	186801|Clostridia	L	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
PKFBPKFJ_01857	1121115.AXVN01000007_gene3543	4.16e-53	168.0	2DM28@1|root,31EE5@2|Bacteria,1VBAV@1239|Firmicutes,24NVF@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PKFBPKFJ_01858	1121115.AXVN01000007_gene3544	0.0	900.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,248VT@186801|Clostridia,3Y1PS@572511|Blautia	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PKFBPKFJ_01859	1121115.AXVN01000007_gene3545	5.63e-181	509.0	2DUM5@1|root,33R7W@2|Bacteria,1VTZM@1239|Firmicutes,24YQK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01861	1121115.AXVN01000007_gene3547	2.64e-251	692.0	2CF7U@1|root,2Z7U3@2|Bacteria,1UYHD@1239|Firmicutes,24C76@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
PKFBPKFJ_01862	1121115.AXVN01000007_gene3548	0.0	1351.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,3Y16N@572511|Blautia	186801|Clostridia	U	Type IV secretion-system coupling protein DNA-binding domain	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
PKFBPKFJ_01863	1121115.AXVN01000007_gene3549	4.24e-62	191.0	299KT@1|root,2ZWP8@2|Bacteria,1V5IJ@1239|Firmicutes,24N53@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01864	1121115.AXVN01000007_gene3550	1.38e-189	527.0	2DB6V@1|root,2Z7IJ@2|Bacteria,1TRNS@1239|Firmicutes,24ANE@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01865	1121115.AXVN01000007_gene3551	4.83e-220	607.0	COG0863@1|root,COG0863@2|Bacteria,1UDII@1239|Firmicutes,248HX@186801|Clostridia	186801|Clostridia	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
PKFBPKFJ_01866	1121115.AXVN01000007_gene3552	1.2e-195	542.0	28NFE@1|root,2ZBHQ@2|Bacteria,1UFEH@1239|Firmicutes,24E0F@186801|Clostridia,3Y0K0@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4313
PKFBPKFJ_01867	1121115.AXVN01000007_gene3553	1.73e-89	265.0	28XQJ@1|root,2ZJM8@2|Bacteria,1V2X9@1239|Firmicutes,24NE5@186801|Clostridia	186801|Clostridia	S	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
PKFBPKFJ_01868	1121115.AXVN01000007_gene3554	0.0	1561.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
PKFBPKFJ_01869	1121115.AXVN01000007_gene3556	7.95e-103	299.0	COG2003@1|root,COG2003@2|Bacteria,1V38E@1239|Firmicutes,24M00@186801|Clostridia	186801|Clostridia	L	DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	RadC
PKFBPKFJ_01871	1121115.AXVN01000007_gene3557	3.3e-130	370.0	28N9F@1|root,2ZBDG@2|Bacteria,1V0YX@1239|Firmicutes	1239|Firmicutes	S	Domain of unknown function (DUF4433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4433
PKFBPKFJ_01872	1121115.AXVN01000007_gene3558	6.93e-231	637.0	COG2110@1|root,COG2110@2|Bacteria,1UY8V@1239|Firmicutes,24C22@186801|Clostridia	186801|Clostridia	S	Macro domain	-	-	-	-	-	-	-	-	-	-	-	-	Macro
PKFBPKFJ_01873	1121115.AXVN01000007_gene3559	1.87e-290	796.0	COG4227@1|root,COG4227@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ArdA,DUF4316,Peptidase_M78,YodL
PKFBPKFJ_01874	1121115.AXVN01000007_gene3560	2.31e-191	534.0	COG0175@1|root,COG0175@2|Bacteria,1TSMI@1239|Firmicutes,24A18@186801|Clostridia	186801|Clostridia	EH	Phosphoadenosine phosphosulfate reductase	-	-	-	-	-	-	-	-	-	-	-	-	PAPS_reduct
PKFBPKFJ_01875	1121115.AXVN01000007_gene3561	1.29e-105	305.0	2EY0E@1|root,33R9F@2|Bacteria,1VS7K@1239|Firmicutes,24XU5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01876	1121115.AXVN01000007_gene3562	0.0	1260.0	COG0791@1|root,COG3584@1|root,COG0791@2|Bacteria,COG3584@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,3XYSD@572511|Blautia	186801|Clostridia	M	Psort location Extracellular, score 9.55	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60
PKFBPKFJ_01878	1121115.AXVN01000007_gene3564	2.32e-100	323.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria	2|Bacteria	L	DNA restriction-modification system	XK27_00500	-	-	-	-	-	-	-	-	-	-	-	Eco57I,Helicase_C,N6_Mtase,ResIII,SNF2_N
PKFBPKFJ_01881	478749.BRYFOR_06660	9.32e-55	177.0	COG1595@1|root,COG1595@2|Bacteria,1V1JW@1239|Firmicutes,24FYN@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_01882	622312.ROSEINA2194_03142	3.48e-145	420.0	COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,24CFF@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PKFBPKFJ_01883	1235802.C823_03611	5.05e-55	179.0	2ENMS@1|root,33G93@2|Bacteria,1VMF6@1239|Firmicutes,24QEZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01885	411483.FAEPRAA2165_00220	2.81e-140	402.0	COG4942@1|root,COG4942@2|Bacteria,1V67C@1239|Firmicutes,25FCI@186801|Clostridia,3WSPR@541000|Ruminococcaceae	186801|Clostridia	D	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
PKFBPKFJ_01886	411459.RUMOBE_03557	6.49e-30	115.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24A4M@186801|Clostridia,3Y0YZ@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
PKFBPKFJ_01887	1121115.AXVN01000041_gene2574	3.05e-129	370.0	COG2860@1|root,COG2860@2|Bacteria,1UH1K@1239|Firmicutes,24HHG@186801|Clostridia,3XYJI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yicG	-	-	-	-	-	-	-	-	-	-	-	UPF0126
PKFBPKFJ_01888	1121115.AXVN01000041_gene2581	0.0	1110.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,3XYYP@572511|Blautia	186801|Clostridia	P	COG COG0004 Ammonia permease	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
PKFBPKFJ_01889	457412.RSAG_01359	0.0	1391.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
PKFBPKFJ_01890	457412.RSAG_01358	0.0	939.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3WH6T@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
PKFBPKFJ_01891	1121115.AXVN01000041_gene2584	2.26e-46	149.0	COG1925@1|root,COG1925@2|Bacteria,1VEJ5@1239|Firmicutes,24R2F@186801|Clostridia,3Y0M0@572511|Blautia	186801|Clostridia	G	phosphocarrier protein HPr	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
PKFBPKFJ_01892	457412.RSAG_01356	0.0	1082.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,3WGE8@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
PKFBPKFJ_01893	1121115.AXVN01000041_gene2586	0.0	2984.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3XZ2S@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
PKFBPKFJ_01894	1121115.AXVN01000041_gene2587	0.0	993.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3XZHX@572511|Blautia	186801|Clostridia	C	NADH-dependent glutamate synthase small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
PKFBPKFJ_01895	1121115.AXVN01000041_gene2589	2.89e-50	159.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3XZN0@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_01896	1121115.AXVN01000041_gene2590	7.21e-33	114.0	2C5R4@1|root,2ZP19@2|Bacteria,1W6F9@1239|Firmicutes,255YP@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PKFBPKFJ_01897	1121115.AXVN01000041_gene2591	3.01e-190	529.0	COG0789@1|root,COG0789@2|Bacteria,1UZ91@1239|Firmicutes,249BQ@186801|Clostridia,3Y1VF@572511|Blautia	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,MerR_1,RDD
PKFBPKFJ_01898	1121115.AXVN01000041_gene2592	1.02e-163	458.0	COG1131@1|root,COG1131@2|Bacteria,1V4NG@1239|Firmicutes	1239|Firmicutes	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PKFBPKFJ_01899	457412.RSAG_01348	2.06e-261	718.0	2F0KS@1|root,33TPE@2|Bacteria,1VTU9@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01900	1121115.AXVN01000041_gene2593	3.09e-56	174.0	2CM8T@1|root,32SE0@2|Bacteria,1VBP1@1239|Firmicutes,24Q65@186801|Clostridia	186801|Clostridia	S	HicA toxin of bacterial toxin-antitoxin,	-	-	-	-	-	-	-	-	-	-	-	-	HicA_toxin
PKFBPKFJ_01901	1121115.AXVN01000041_gene2594	1.38e-82	244.0	COG1598@1|root,COG1598@2|Bacteria,1VAII@1239|Firmicutes,24I04@186801|Clostridia	186801|Clostridia	S	HicB family	-	-	-	ko:K18843	-	-	-	-	ko00000,ko02048	-	-	-	HicB,HicB_lk_antitox
PKFBPKFJ_01902	1121115.AXVN01000041_gene2595	0.0	893.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,3XYYT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
PKFBPKFJ_01903	1121115.AXVN01000041_gene2596	1.32e-120	345.0	COG3707@1|root,COG3707@2|Bacteria,1V2S1@1239|Firmicutes,24EWG@186801|Clostridia,3Y020@572511|Blautia	186801|Clostridia	K	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR
PKFBPKFJ_01904	1121115.AXVN01000041_gene2597	0.0	893.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia,3XZ7F@572511|Blautia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
PKFBPKFJ_01905	1121115.AXVN01000041_gene2598	3.23e-59	183.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,3Y0HE@572511|Blautia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
PKFBPKFJ_01906	1121115.AXVN01000041_gene2599	0.0	957.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,3XZNT@572511|Blautia	186801|Clostridia	H	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
PKFBPKFJ_01907	1121115.AXVN01000041_gene2600	0.0	950.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,3XYZ1@572511|Blautia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
PKFBPKFJ_01908	1121115.AXVN01000041_gene2601	2.15e-302	823.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,3XYT4@572511|Blautia	186801|Clostridia	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
PKFBPKFJ_01909	411459.RUMOBE_02146	1.36e-29	116.0	COG1196@1|root,COG1196@2|Bacteria,1UHVD@1239|Firmicutes,25E44@186801|Clostridia,3Y28J@572511|Blautia	186801|Clostridia	D	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PKFBPKFJ_01910	1121115.AXVN01000187_gene1812	2.67e-293	800.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,247ZX@186801|Clostridia,3XZIJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14,DUF4143
PKFBPKFJ_01911	457412.RSAG_03523	2.87e-106	306.0	COG1943@1|root,COG1943@2|Bacteria,1VAIQ@1239|Firmicutes,24IPG@186801|Clostridia,3WRVG@541000|Ruminococcaceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
PKFBPKFJ_01912	457412.RSAG_04545	2.72e-58	191.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
PKFBPKFJ_01913	457412.RSAG_04545	5.61e-301	828.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
PKFBPKFJ_01914	658659.HMPREF0983_03978	0.0	1250.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,3VP95@526524|Erysipelotrichia	526524|Erysipelotrichia	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
PKFBPKFJ_01915	665950.HMPREF1025_00445	0.0	1248.0	COG3064@1|root,COG3064@2|Bacteria,1UIYZ@1239|Firmicutes,249MX@186801|Clostridia,27KYQ@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01916	411470.RUMGNA_02431	3.21e-244	670.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,3XZR2@572511|Blautia	186801|Clostridia	M	COG COG0791 Cell wall-associated hydrolases (invasion-associated proteins)	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
PKFBPKFJ_01917	665950.HMPREF1025_00447	3.29e-205	569.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,27KG9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
PKFBPKFJ_01918	445973.CLOBAR_01097	8.58e-65	197.0	2C010@1|root,32R65@2|Bacteria,1V8U5@1239|Firmicutes,24VZW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01919	742765.HMPREF9457_03585	3.02e-40	133.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,27X39@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
PKFBPKFJ_01920	742765.HMPREF9457_03584	7.44e-66	201.0	2B03C@1|root,31SDP@2|Bacteria,1V89U@1239|Firmicutes,24NN6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
PKFBPKFJ_01921	445973.CLOBAR_01094	4.11e-46	148.0	COG0582@1|root,COG0582@2|Bacteria,1VBGF@1239|Firmicutes,24NRM@186801|Clostridia,25U1Z@186804|Peptostreptococcaceae	186801|Clostridia	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01922	1256908.HMPREF0373_00068	1.44e-180	503.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_01923	1256908.HMPREF0373_00067	0.0	1198.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,25V5H@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PKFBPKFJ_01924	1256908.HMPREF0373_00066	5.98e-152	427.0	COG0745@1|root,COG0745@2|Bacteria,1V12F@1239|Firmicutes,24D2Z@186801|Clostridia,25Y6N@186806|Eubacteriaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_01925	658088.HMPREF0987_00213	6.68e-238	654.0	COG0642@1|root,COG0642@2|Bacteria,1TQSG@1239|Firmicutes,25EB7@186801|Clostridia,27UGH@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
PKFBPKFJ_01926	658088.HMPREF0987_00212	2.61e-96	280.0	COG1595@1|root,COG1595@2|Bacteria,1TSMC@1239|Firmicutes,24FTZ@186801|Clostridia,27MU1@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
PKFBPKFJ_01927	1121333.JMLH01000019_gene1519	2.31e-52	164.0	2BVCS@1|root,32QSU@2|Bacteria,1UHK3@1239|Firmicutes	1239|Firmicutes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
PKFBPKFJ_01928	500632.CLONEX_03693	1.15e-35	121.0	2EQGP@1|root,33I2P@2|Bacteria,1VKY1@1239|Firmicutes,24SQ3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01929	500632.CLONEX_03692	9.28e-292	796.0	COG0582@1|root,COG0582@2|Bacteria,1VRCP@1239|Firmicutes,24BDU@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_01930	457412.RSAG_01682	1.06e-105	305.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3WHNP@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
PKFBPKFJ_01931	457412.RSAG_01681	1.34e-108	312.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3WHNP@541000|Ruminococcaceae	186801|Clostridia	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
PKFBPKFJ_01932	1121115.AXVN01000014_gene1239	1.49e-238	659.0	COG0484@1|root,COG0484@2|Bacteria,1TS44@1239|Firmicutes,24A9N@186801|Clostridia,3XYJ1@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	CbpA	-	-	ko:K05516	-	-	-	-	ko00000,ko03036,ko03110	-	-	-	DnaJ,DnaJ_C
PKFBPKFJ_01933	457412.RSAG_01679	1.47e-211	583.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia,3WHMV@541000|Ruminococcaceae	186801|Clostridia	L	NADH pyrophosphatase zinc ribbon domain	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
PKFBPKFJ_01934	1121115.AXVN01000014_gene1241	2.23e-283	773.0	COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,247W5@186801|Clostridia,3Y0AK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	mdh	-	-	-	-	-	-	-	-	-	-	-	Ldh_2
PKFBPKFJ_01935	457412.RSAG_01677	2.34e-92	271.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,3WKS1@541000|Ruminococcaceae	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
PKFBPKFJ_01936	1121115.AXVN01000014_gene1243	6.3e-224	618.0	2BADS@1|root,323U8@2|Bacteria,1VTZ8@1239|Firmicutes,24ZP1@186801|Clostridia,3Y1JU@572511|Blautia	186801|Clostridia	S	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01937	1121115.AXVN01000014_gene1244	5.75e-213	589.0	COG2367@1|root,COG2367@2|Bacteria,1VSGY@1239|Firmicutes,24XQF@186801|Clostridia,3XZU7@572511|Blautia	186801|Clostridia	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
PKFBPKFJ_01938	1121115.AXVN01000014_gene1245	2.4e-268	732.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,3Y1E6@572511|Blautia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
PKFBPKFJ_01940	457412.RSAG_01673	1.99e-195	541.0	COG1410@1|root,COG1410@2|Bacteria,1UV7K@1239|Firmicutes,25CEH@186801|Clostridia,3WSCG@541000|Ruminococcaceae	186801|Clostridia	E	Pterin binding enzyme	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
PKFBPKFJ_01941	1121115.AXVN01000014_gene1247	5.21e-138	391.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,3Y0XR@572511|Blautia	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
PKFBPKFJ_01942	1121115.AXVN01000014_gene1248	0.0	1106.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3Y14F@572511|Blautia	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
PKFBPKFJ_01943	457412.RSAG_01670	2.61e-133	377.0	COG5423@1|root,COG5423@2|Bacteria,1V8Y4@1239|Firmicutes,24EAF@186801|Clostridia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
PKFBPKFJ_01944	1121115.AXVN01000164_gene904	1.14e-141	400.0	COG5012@1|root,COG5012@2|Bacteria,1VSJU@1239|Firmicutes,24XK2@186801|Clostridia,3Y145@572511|Blautia	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
PKFBPKFJ_01945	457412.RSAG_01667	0.0	1019.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,3WM6D@541000|Ruminococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
PKFBPKFJ_01946	457412.RSAG_01666	1.06e-126	362.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia,3WJUS@541000|Ruminococcaceae	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
PKFBPKFJ_01947	457412.RSAG_01665	6.23e-267	731.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3WGWM@541000|Ruminococcaceae	186801|Clostridia	G	Glucose-1-phosphate adenylyltransferase, GlgD subunit	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
PKFBPKFJ_01948	457412.RSAG_01664	4.75e-250	689.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3WGWG@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
PKFBPKFJ_01949	1121115.AXVN01000147_gene3490	0.0	926.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,3XZJ0@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
PKFBPKFJ_01950	1121115.AXVN01000147_gene3491	1.76e-185	515.0	COG0463@1|root,COG0463@2|Bacteria,1TSPS@1239|Firmicutes,25FHJ@186801|Clostridia,3Y1C1@572511|Blautia	186801|Clostridia	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PKFBPKFJ_01951	457412.RSAG_03495	0.0	867.0	COG3594@1|root,COG3594@2|Bacteria	2|Bacteria	G	nodulation	-	-	-	ko:K13663	-	-	-	-	ko00000,ko01000	-	-	-	Acyl_transf_3
PKFBPKFJ_01952	457412.RSAG_01661	9.56e-317	862.0	COG0615@1|root,COG0673@1|root,COG0615@2|Bacteria,COG0673@2|Bacteria,1V3KY@1239|Firmicutes,24BKY@186801|Clostridia,3WIHC@541000|Ruminococcaceae	186801|Clostridia	IM	Cytidylyltransferase-like	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like,GFO_IDH_MocA
PKFBPKFJ_01953	457412.RSAG_01660	0.0	1553.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,3WKER@541000|Ruminococcaceae	186801|Clostridia	M	LicD family	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
PKFBPKFJ_01954	457412.RSAG_01659	2.95e-284	776.0	COG3475@1|root,COG3475@2|Bacteria	2|Bacteria	M	LICD family	licD	-	-	ko:K02011,ko:K07271,ko:K19872	ko00515,ko01100,ko02010,map00515,map01100,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000,ko04131	3.A.1.10	-	-	LicD
PKFBPKFJ_01955	1121115.AXVN01000121_gene2848	0.0	1172.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3XZCN@572511|Blautia	186801|Clostridia	H	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	-	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
PKFBPKFJ_01956	1121115.AXVN01000121_gene2849	2.41e-178	496.0	COG1028@1|root,COG1028@2|Bacteria,1V2KA@1239|Firmicutes,24GZZ@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PKFBPKFJ_01957	1121115.AXVN01000018_gene13	7.29e-46	147.0	COG0267@1|root,COG0267@2|Bacteria,1VEJ4@1239|Firmicutes,24QK0@186801|Clostridia,3Y0JI@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL33 family	rpmG	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
PKFBPKFJ_01958	1121115.AXVN01000018_gene14	1.44e-38	129.0	COG0690@1|root,COG0690@2|Bacteria,1VH7Y@1239|Firmicutes,24RJ1@186801|Clostridia,3Y0SS@572511|Blautia	186801|Clostridia	U	SecE/Sec61-gamma subunits of protein translocation complex	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
PKFBPKFJ_01959	1121115.AXVN01000018_gene15	3.32e-119	340.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3XZ8Y@572511|Blautia	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
PKFBPKFJ_01960	1121115.AXVN01000018_gene16	3.14e-89	262.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3XZUC@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
PKFBPKFJ_01961	1121115.AXVN01000018_gene17	3.53e-159	446.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
PKFBPKFJ_01962	457412.RSAG_01651	1.78e-239	658.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,24AQE@186801|Clostridia,3WGMZ@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
PKFBPKFJ_01963	1121115.AXVN01000018_gene19	1.39e-57	180.0	2EUJQ@1|root,33N1P@2|Bacteria,1VMKN@1239|Firmicutes,250D1@186801|Clostridia,3Y0U5@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_01964	1121115.AXVN01000018_gene20	1.23e-128	365.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
PKFBPKFJ_01965	1121115.AXVN01000018_gene21	2.24e-96	280.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,3Y0CR@572511|Blautia	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
PKFBPKFJ_01966	1121115.AXVN01000018_gene22	0.0	926.0	COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,24ADD@186801|Clostridia,3Y0F7@572511|Blautia	186801|Clostridia	S	Archaea bacterial proteins of unknown function	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
PKFBPKFJ_01967	1280698.AUJS01000008_gene871	8.43e-18	80.9	COG4974@1|root,COG4974@2|Bacteria,1TS3U@1239|Firmicutes,24EMD@186801|Clostridia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
PKFBPKFJ_01968	1280698.AUJS01000008_gene871	1.95e-218	604.0	COG4974@1|root,COG4974@2|Bacteria,1TS3U@1239|Firmicutes,24EMD@186801|Clostridia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
PKFBPKFJ_01969	1280698.AUJS01000008_gene870	2.65e-16	77.0	COG0582@1|root,COG0582@2|Bacteria,1V0BP@1239|Firmicutes,24D2Q@186801|Clostridia,27WST@189330|Dorea	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PKFBPKFJ_01970	1280698.AUJS01000008_gene869	2.74e-30	115.0	COG0582@1|root,COG0582@2|Bacteria,1V78A@1239|Firmicutes,24I4Z@186801|Clostridia,27WXR@189330|Dorea	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PKFBPKFJ_01971	1121115.AXVN01000018_gene28	0.0	875.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3XZZ6@572511|Blautia	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
PKFBPKFJ_01972	1121115.AXVN01000018_gene29	0.0	1018.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,2482B@186801|Clostridia,3Y0RM@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
PKFBPKFJ_01973	1121115.AXVN01000018_gene30	1.61e-55	179.0	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,3Y03Y@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
PKFBPKFJ_01974	1121115.AXVN01000018_gene30	5.84e-101	298.0	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,3Y03Y@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
PKFBPKFJ_01975	1121115.AXVN01000018_gene31	1.93e-119	342.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,3XZUW@572511|Blautia	186801|Clostridia	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
PKFBPKFJ_01976	1121115.AXVN01000018_gene32	1.29e-123	353.0	COG2059@1|root,COG2059@2|Bacteria,1V22C@1239|Firmicutes,24G7P@186801|Clostridia,3XZU9@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
PKFBPKFJ_01977	1121115.AXVN01000018_gene33	1.53e-212	587.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,24970@186801|Clostridia,3Y0C6@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_01979	1121115.AXVN01000018_gene35	5.08e-245	673.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,247Z9@186801|Clostridia,3XZWW@572511|Blautia	186801|Clostridia	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
PKFBPKFJ_01980	457412.RSAG_01646	0.0	1318.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3WGEI@541000|Ruminococcaceae	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
PKFBPKFJ_01981	1121115.AXVN01000018_gene37	7.13e-110	316.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,3Y01J@572511|Blautia	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
PKFBPKFJ_01982	457412.RSAG_01644	1.95e-109	315.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,3WHT9@541000|Ruminococcaceae	186801|Clostridia	H	Molybdenum cofactor synthesis domain protein	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
PKFBPKFJ_01983	457412.RSAG_01643	1.82e-102	296.0	COG2258@1|root,COG2258@2|Bacteria,1UIYW@1239|Firmicutes,25FCC@186801|Clostridia	186801|Clostridia	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	MOSC
PKFBPKFJ_01984	1121115.AXVN01000018_gene40	1.05e-183	511.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3XZFC@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
PKFBPKFJ_01985	457412.RSAG_01641	0.0	923.0	COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,24950@186801|Clostridia,3WIMU@541000|Ruminococcaceae	186801|Clostridia	M	Capsule synthesis protein	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
PKFBPKFJ_01986	1121115.AXVN01000018_gene42	8.76e-96	280.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia,3Y09U@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
PKFBPKFJ_01987	1121115.AXVN01000018_gene43	1.11e-52	175.0	COG0503@1|root,COG0503@2|Bacteria,1UZSF@1239|Firmicutes,24FUM@186801|Clostridia,3Y1E0@572511|Blautia	186801|Clostridia	F	Phosphoribosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PRTase_2,TRSP
PKFBPKFJ_01988	457412.RSAG_01528	6.23e-212	585.0	COG2207@1|root,COG2207@2|Bacteria,1UYSR@1239|Firmicutes,248R9@186801|Clostridia,3WJXM@541000|Ruminococcaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
PKFBPKFJ_01989	457412.RSAG_01529	0.0	1442.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3WH8U@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
PKFBPKFJ_01990	457412.RSAG_01530	0.0	1152.0	COG2972@1|root,COG2972@2|Bacteria,1V4G9@1239|Firmicutes,24IA9@186801|Clostridia,3WP6J@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
PKFBPKFJ_01991	457412.RSAG_01531	5.24e-193	536.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V27N@1239|Firmicutes,24EUU@186801|Clostridia,3WPI2@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
PKFBPKFJ_01992	457412.RSAG_01532	7.99e-189	525.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3WIS9@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PKFBPKFJ_01993	457412.RSAG_01533	3.45e-206	570.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3WJ61@541000|Ruminococcaceae	186801|Clostridia	P	transport systems	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PKFBPKFJ_01994	457412.RSAG_01534	0.0	870.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia,3WJP9@541000|Ruminococcaceae	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
PKFBPKFJ_01995	457412.RSAG_01535	0.0	1423.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3WH8U@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
PKFBPKFJ_01996	457412.RSAG_01536	3.7e-298	814.0	COG2207@1|root,COG2207@2|Bacteria,1TQD7@1239|Firmicutes,249SA@186801|Clostridia,3WP6K@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
PKFBPKFJ_01997	457412.RSAG_01537	0.0	1403.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia,3WRXQ@541000|Ruminococcaceae	186801|Clostridia	G	family 31 of glycosyl	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
PKFBPKFJ_01998	457412.RSAG_01538	3.39e-190	529.0	COG0395@1|root,COG0395@2|Bacteria,1UN1I@1239|Firmicutes,249S1@186801|Clostridia,3WI7U@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_01999	457412.RSAG_01539	3.7e-204	566.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,3WN1Y@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport systems permease components	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PKFBPKFJ_02000	457412.RSAG_01540	1.23e-297	811.0	COG1653@1|root,COG1653@2|Bacteria,1TRAX@1239|Firmicutes,2497E@186801|Clostridia,3WH7S@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
PKFBPKFJ_02001	457412.RSAG_01541	3.14e-167	468.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24BBP@186801|Clostridia,3WJP7@541000|Ruminococcaceae	186801|Clostridia	K	Response regulator receiver domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
PKFBPKFJ_02002	457412.RSAG_01542	0.0	1142.0	COG2972@1|root,COG2972@2|Bacteria,1TW41@1239|Firmicutes,24AHF@186801|Clostridia,3WJ2Z@541000|Ruminococcaceae	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,dCache_1
PKFBPKFJ_02003	457412.RSAG_01543	7.47e-148	416.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia,3WHMB@541000|Ruminococcaceae	186801|Clostridia	G	2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
PKFBPKFJ_02004	457412.RSAG_01544	4.93e-270	737.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3WI8G@541000|Ruminococcaceae	186801|Clostridia	H	Kinase, PfkB family	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
PKFBPKFJ_02005	457412.RSAG_01545	0.0	1166.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3WGPR@541000|Ruminococcaceae	186801|Clostridia	EG	Belongs to the IlvD Edd family	ilvD3	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
PKFBPKFJ_02006	33035.JPJF01000045_gene1036	1.78e-90	279.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia,3Y1GE@572511|Blautia	186801|Clostridia	EG	GntP family permease	-	-	-	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.4,2.A.8.1.8	-	iHN637.CLJU_RS05690,iHN637.CLJU_RS13905	GntP_permease
PKFBPKFJ_02007	33035.JPJF01000045_gene1036	6.36e-31	120.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia,3Y1GE@572511|Blautia	186801|Clostridia	EG	GntP family permease	-	-	-	ko:K03299,ko:K06155,ko:K06156,ko:K06157	-	-	-	-	ko00000,ko02000	2.A.8,2.A.8.1.2,2.A.8.1.4,2.A.8.1.8	-	iHN637.CLJU_RS05690,iHN637.CLJU_RS13905	GntP_permease
PKFBPKFJ_02008	457412.RSAG_01546	2.47e-166	466.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia,3WKKW@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
PKFBPKFJ_02009	457412.RSAG_01547	4.41e-218	602.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,3WGJW@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_02010	457412.RSAG_01548	2.67e-253	696.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,3WGR3@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
PKFBPKFJ_02011	457412.RSAG_01549	1.7e-84	249.0	2DSCR@1|root,33FK0@2|Bacteria,1VKCD@1239|Firmicutes,24QWS@186801|Clostridia,3WM8E@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3783
PKFBPKFJ_02012	457412.RSAG_01551	3.91e-270	742.0	COG1301@1|root,COG1301@2|Bacteria,1TPME@1239|Firmicutes,247UX@186801|Clostridia,3WISY@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
PKFBPKFJ_02013	1121115.AXVN01000108_gene627	0.0	984.0	COG1621@1|root,COG1621@2|Bacteria,1U0EK@1239|Firmicutes,24AM9@186801|Clostridia,3Y1NF@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF4975)	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	DUF4975,Glyco_hydro_32N
PKFBPKFJ_02014	457412.RSAG_01553	6.61e-193	536.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249S6@186801|Clostridia,3WP49@541000|Ruminococcaceae	186801|Clostridia	P	COG COG0395 ABC-type sugar transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_02015	457412.RSAG_01554	1.15e-205	569.0	COG1175@1|root,COG1175@2|Bacteria,1TRI2@1239|Firmicutes,24DZ7@186801|Clostridia,3WP6P@541000|Ruminococcaceae	186801|Clostridia	P	COG COG1175 ABC-type sugar transport systems, permease components	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_02016	457412.RSAG_01555	1.63e-295	808.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
PKFBPKFJ_02017	1121115.AXVN01000042_gene3041	2.75e-210	580.0	COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,24AYF@186801|Clostridia,3Y06U@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_02018	1121115.AXVN01000042_gene3040	0.0	872.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3Y1DM@572511|Blautia	186801|Clostridia	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
PKFBPKFJ_02019	457412.RSAG_01705	3.42e-157	441.0	COG0637@1|root,COG0637@2|Bacteria,1V1IW@1239|Firmicutes,24FZZ@186801|Clostridia,3WRQ7@541000|Ruminococcaceae	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	CpXC,HAD_2
PKFBPKFJ_02020	1121115.AXVN01000042_gene3038	0.0	887.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,3XYVQ@572511|Blautia	186801|Clostridia	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
PKFBPKFJ_02021	1121115.AXVN01000042_gene3037	1.4e-90	265.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia,3Y05D@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02022	1121115.AXVN01000042_gene3036	0.0	1553.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3XYKC@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 9.98	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
PKFBPKFJ_02023	457412.RSAG_01709	9.51e-81	239.0	COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,24J7Q@186801|Clostridia,3WJKW@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
PKFBPKFJ_02024	1121115.AXVN01000042_gene3034	5.63e-178	496.0	28NW4@1|root,30Q9J@2|Bacteria,1V4ZJ@1239|Firmicutes,24GHA@186801|Clostridia,3XZZE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	SseB
PKFBPKFJ_02025	1121115.AXVN01000042_gene3033	6.13e-174	484.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia,3XZY3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
PKFBPKFJ_02026	1121115.AXVN01000042_gene3032	1.14e-314	856.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,3XYZ3@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
PKFBPKFJ_02027	1121115.AXVN01000042_gene3031	1.83e-148	418.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,3XYPA@572511|Blautia	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
PKFBPKFJ_02028	1121115.AXVN01000042_gene3030	4.78e-249	683.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,3XYWD@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
PKFBPKFJ_02029	1121115.AXVN01000042_gene3029	1.31e-109	316.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3XZ51@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
PKFBPKFJ_02030	1121115.AXVN01000042_gene3028	0.0	1358.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia,3XYTQ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
PKFBPKFJ_02031	1121115.AXVN01000042_gene3027	4.05e-64	196.0	2EENY@1|root,338GS@2|Bacteria,1VJM1@1239|Firmicutes,24T09@186801|Clostridia,3Y0JX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02032	457412.RSAG_01717	3.03e-106	306.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia,3WK49@541000|Ruminococcaceae	186801|Clostridia	V	Glycopeptide antibiotics resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
PKFBPKFJ_02033	1121115.AXVN01000042_gene3025	6.09e-24	90.9	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia,3Y0RQ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02034	1121115.AXVN01000042_gene3024	2.7e-161	451.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,3XYW9@572511|Blautia	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
PKFBPKFJ_02035	1121115.AXVN01000042_gene3023	2.17e-213	589.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,3XZ9C@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
PKFBPKFJ_02036	1121115.AXVN01000042_gene3022	2.94e-192	533.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,3XZA9@572511|Blautia	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
PKFBPKFJ_02037	1121115.AXVN01000042_gene3021	4.46e-226	622.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,3XZ6C@572511|Blautia	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
PKFBPKFJ_02038	1121115.AXVN01000042_gene3020	0.0	864.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,3XYP9@572511|Blautia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
PKFBPKFJ_02039	1121115.AXVN01000042_gene3019	1.04e-41	136.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,3Y0CS@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
PKFBPKFJ_02040	1121115.AXVN01000042_gene3018	7.64e-61	192.0	2DUBB@1|root,33PT0@2|Bacteria,1VSM4@1239|Firmicutes,24YVT@186801|Clostridia,3Y0NE@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02041	1121115.AXVN01000042_gene3017	2.51e-197	547.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,3XYU8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DegV
PKFBPKFJ_02042	1121115.AXVN01000042_gene3016	9.24e-119	339.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia,3Y05S@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02043	1121115.AXVN01000042_gene3015	7.42e-75	223.0	COG0745@1|root,COG0745@2|Bacteria,1UK3F@1239|Firmicutes,25FI6@186801|Clostridia,3Y0KY@572511|Blautia	186801|Clostridia	KT	Sporulation initiation factor Spo0A C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
PKFBPKFJ_02044	1121115.AXVN01000042_gene3014	0.0	1359.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,3XZ94@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
PKFBPKFJ_02045	1121115.AXVN01000042_gene3013	0.0	1459.0	COG1361@1|root,COG1361@2|Bacteria	2|Bacteria	M	extracellular matrix structural constituent	-	-	-	-	-	-	-	-	-	-	-	-	ArabFuran-catal,CHU_C,DUF11,IgGFc_binding,LTD,NPCBM_assoc,Peptidase_M11,SprB
PKFBPKFJ_02046	457412.RSAG_01731	2.36e-51	162.0	2E51P@1|root,32ZV2@2|Bacteria,1VFYG@1239|Firmicutes,24QWN@186801|Clostridia,3WKYT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02047	1121115.AXVN01000042_gene3011	9.4e-192	532.0	COG0561@1|root,COG0561@2|Bacteria,1V43V@1239|Firmicutes,24AQQ@186801|Clostridia,3XZTP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
PKFBPKFJ_02048	1121115.AXVN01000042_gene3010	1.11e-162	454.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia,3XZXU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
PKFBPKFJ_02049	457412.RSAG_01734	5.75e-135	382.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3WJIZ@541000|Ruminococcaceae	186801|Clostridia	D	Maf-like protein	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
PKFBPKFJ_02050	1121115.AXVN01000042_gene3008	2.69e-46	153.0	2F1AC@1|root,33UBB@2|Bacteria,1VUR2@1239|Firmicutes,2503K@186801|Clostridia,3Y24T@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02051	457412.RSAG_01736	0.0	1137.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,3WH6G@541000|Ruminococcaceae	186801|Clostridia	J	glutaminyl-tRNA synthetase	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
PKFBPKFJ_02052	457412.RSAG_00860	3.14e-132	374.0	COG3760@1|root,COG3760@2|Bacteria,1V1JF@1239|Firmicutes,24FVD@186801|Clostridia,3WIZ6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K19055	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
PKFBPKFJ_02053	457412.RSAG_00862	6.51e-216	596.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
PKFBPKFJ_02054	457412.RSAG_00863	1.06e-230	633.0	COG1533@1|root,COG1533@2|Bacteria,1TRIS@1239|Firmicutes,25CEW@186801|Clostridia,3WGZD@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
PKFBPKFJ_02055	1280698.AUJS01000042_gene3266	1.58e-175	488.0	COG4422@1|root,COG4422@2|Bacteria,1TPRY@1239|Firmicutes,247VT@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF5131
PKFBPKFJ_02056	457412.RSAG_00865	6.05e-98	285.0	COG1846@1|root,COG1846@2|Bacteria,1V8KT@1239|Firmicutes,24B99@186801|Clostridia,3WGSA@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulators	mgrA	-	-	-	-	-	-	-	-	-	-	-	MarR
PKFBPKFJ_02057	457412.RSAG_03509	6.83e-76	226.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia,3WJW2@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, HxlR family	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
PKFBPKFJ_02058	457412.RSAG_00877	5.05e-79	234.0	COG0662@1|root,COG0662@2|Bacteria,1V7HI@1239|Firmicutes,24JQZ@186801|Clostridia,3WPJX@541000|Ruminococcaceae	186801|Clostridia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PKFBPKFJ_02059	457412.RSAG_00878	0.0	1938.0	COG1315@1|root,COG1315@2|Bacteria,1TRQX@1239|Firmicutes,24BWZ@186801|Clostridia,3WHD4@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,SLH
PKFBPKFJ_02060	457412.RSAG_00879	1.74e-179	514.0	2BHPW@1|root,32BT5@2|Bacteria,1VKP8@1239|Firmicutes,24XAG@186801|Clostridia	186801|Clostridia	S	SANT  SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02061	457412.RSAG_00880	0.0	1114.0	COG1961@1|root,COG1961@2|Bacteria,1TWK9@1239|Firmicutes,24C30@186801|Clostridia,3WHD6@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_02063	457412.RSAG_00882	1.02e-183	510.0	COG1402@1|root,COG1402@2|Bacteria,1V0N8@1239|Firmicutes,24BWG@186801|Clostridia,3WMNU@541000|Ruminococcaceae	186801|Clostridia	S	Creatinine amidohydrolase	-	-	3.5.2.10	ko:K01470,ko:K22232	ko00330,ko00562,map00330,map00562	-	R01884,R11771	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
PKFBPKFJ_02064	457412.RSAG_00883	0.0	933.0	COG4145@1|root,COG4145@2|Bacteria,1UJ00@1239|Firmicutes,25F28@186801|Clostridia	186801|Clostridia	H	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K11928,ko:K14392	-	-	-	-	ko00000,ko02000	2.A.21.1,2.A.21.2	-	-	SSF
PKFBPKFJ_02065	457412.RSAG_00884	1.63e-52	165.0	2E714@1|root,331JV@2|Bacteria,1VQIV@1239|Firmicutes,251NJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02066	457412.RSAG_00885	9.08e-202	559.0	COG1737@1|root,COG1737@2|Bacteria,1VBUB@1239|Firmicutes,24MTV@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
PKFBPKFJ_02067	457412.RSAG_00886	3.03e-278	760.0	COG1820@1|root,COG1820@2|Bacteria,1UK3V@1239|Firmicutes,25FIQ@186801|Clostridia	186801|Clostridia	E	Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation	iadA	-	-	ko:K01305	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Amidohydro_1
PKFBPKFJ_02069	457412.RSAG_00888	6.3e-177	494.0	COG0716@1|root,COG1145@1|root,COG0716@2|Bacteria,COG1145@2|Bacteria,1VSX9@1239|Firmicutes,24ZRM@186801|Clostridia,3WSJJ@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_5
PKFBPKFJ_02070	457412.RSAG_03422	3.56e-221	613.0	COG2199@1|root,COG2199@2|Bacteria,1V1A1@1239|Firmicutes,24CYN@186801|Clostridia,3WN05@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
PKFBPKFJ_02071	457412.RSAG_00891	1.14e-180	503.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,3WHH1@541000|Ruminococcaceae	186801|Clostridia	S	Peroxide stress protein YaaA	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
PKFBPKFJ_02072	457412.RSAG_00892	2.73e-106	306.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,3WIK4@541000|Ruminococcaceae	186801|Clostridia	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
PKFBPKFJ_02073	457412.RSAG_00893	6.87e-24	92.0	2C9RV@1|root,32WXH@2|Bacteria,1VCZ0@1239|Firmicutes,25AYI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02074	457412.RSAG_00894	8.94e-100	289.0	COG2198@1|root,COG3437@1|root,COG2198@2|Bacteria,COG3437@2|Bacteria,1VG8R@1239|Firmicutes,24QS0@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
PKFBPKFJ_02075	457412.RSAG_00895	0.0	1825.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
PKFBPKFJ_02076	457412.RSAG_00896	0.0	1755.0	COG0642@1|root,COG0784@1|root,COG0834@1|root,COG0784@2|Bacteria,COG0834@2|Bacteria,COG2205@2|Bacteria,1TVCK@1239|Firmicutes,25KKE@186801|Clostridia,3WNVM@541000|Ruminococcaceae	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_3
PKFBPKFJ_02077	457412.RSAG_00897	2.5e-203	564.0	COG0842@1|root,COG0842@2|Bacteria,1TSH0@1239|Firmicutes,24BEN@186801|Clostridia,3WM6R@541000|Ruminococcaceae	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992,ko:K11051	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC2_membrane,ABC2_membrane_3
PKFBPKFJ_02078	515620.EUBELI_20171	1.2e-172	487.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,25W4Z@186806|Eubacteriaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K11050	ko02010,map02010	M00254,M00298	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.130	-	-	ABC_tran,DUF4162
PKFBPKFJ_02079	500632.CLONEX_00763	2.62e-33	114.0	COG3177@1|root,COG3177@2|Bacteria,1VISE@1239|Firmicutes,24R8K@186801|Clostridia	186801|Clostridia	S	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02081	457412.RSAG_00900	0.0	1192.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3WSRM@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
PKFBPKFJ_02082	457412.RSAG_00901	5.83e-79	238.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia,3WJ1H@541000|Ruminococcaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
PKFBPKFJ_02083	457412.RSAG_01050	1.34e-235	647.0	COG0407@1|root,COG0407@2|Bacteria,1TNYE@1239|Firmicutes,25NJX@186801|Clostridia,3WQG7@541000|Ruminococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
PKFBPKFJ_02084	457412.RSAG_01049	5.74e-304	828.0	COG1653@1|root,COG1653@2|Bacteria,1TQJE@1239|Firmicutes,2496C@186801|Clostridia,3WK4C@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
PKFBPKFJ_02085	457412.RSAG_01048	2e-206	571.0	COG1175@1|root,COG1175@2|Bacteria,1TQB1@1239|Firmicutes,25C4P@186801|Clostridia,3WSAZ@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PKFBPKFJ_02086	457412.RSAG_01047	4.65e-194	539.0	COG0395@1|root,COG0395@2|Bacteria,1UYHV@1239|Firmicutes,25C4Q@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_02087	457412.RSAG_01046	0.0	999.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1VAG0@1239|Firmicutes,24P6B@186801|Clostridia,3WJQQ@541000|Ruminococcaceae	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	HTH_18,Response_reg
PKFBPKFJ_02088	1121115.AXVN01000019_gene175	0.0	950.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,3Y17X@572511|Blautia	186801|Clostridia	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
PKFBPKFJ_02089	457412.RSAG_01044	5.85e-225	619.0	COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,248NF@186801|Clostridia,3WHCX@541000|Ruminococcaceae	186801|Clostridia	S	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
PKFBPKFJ_02090	1121115.AXVN01000019_gene173	1.28e-284	783.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,3XYV4@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
PKFBPKFJ_02091	457412.RSAG_01042	3.24e-171	479.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,3WIPP@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
PKFBPKFJ_02092	457412.RSAG_01041	1.53e-209	579.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3WGF4@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
PKFBPKFJ_02093	457412.RSAG_01040	0.0	1330.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WJT6@541000|Ruminococcaceae	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
PKFBPKFJ_02094	457412.RSAG_01038	0.0	920.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3WH24@541000|Ruminococcaceae	186801|Clostridia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
PKFBPKFJ_02095	457412.RSAG_01037	1.87e-129	372.0	2DMIV@1|root,32RW6@2|Bacteria,1VAMW@1239|Firmicutes,24DVC@186801|Clostridia,3WJXG@541000|Ruminococcaceae	186801|Clostridia	C	Oxaloacetate decarboxylase, gamma chain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887,OAD_gamma
PKFBPKFJ_02096	1121115.AXVN01000019_gene167	7.37e-54	171.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
PKFBPKFJ_02097	1121115.AXVN01000019_gene166	4.04e-264	724.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,3XZ7I@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
PKFBPKFJ_02098	457412.RSAG_01034	0.0	924.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3WH2N@541000|Ruminococcaceae	186801|Clostridia	C	Pyruvate carboxylase, C-terminal domain subunit K01960	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
PKFBPKFJ_02099	457412.RSAG_01033	0.0	869.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,3WGDB@541000|Ruminococcaceae	186801|Clostridia	S	Flavoprotein family	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
PKFBPKFJ_02100	457412.RSAG_01032	9.69e-149	419.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3WIDU@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
PKFBPKFJ_02101	1121115.AXVN01000019_gene162	4.56e-211	583.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,25E67@186801|Clostridia,3XYNX@572511|Blautia	186801|Clostridia	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
PKFBPKFJ_02102	1121115.AXVN01000019_gene161	2.1e-247	680.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3XZ91@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
PKFBPKFJ_02104	1226325.HMPREF1548_03502	7.55e-11	59.7	2EFE1@1|root,3396U@2|Bacteria,1VK14@1239|Firmicutes,253R2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02105	457412.RSAG_00982	6.39e-89	260.0	COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,24JFW@186801|Clostridia,3WK5Z@541000|Ruminococcaceae	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
PKFBPKFJ_02106	1226325.HMPREF1548_03500	1.68e-150	427.0	2CJZW@1|root,2ZC29@2|Bacteria,1V2Z2@1239|Firmicutes,24H6F@186801|Clostridia,36S8N@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02109	1123309.AQYB01000030_gene1825	1.2e-65	218.0	2BVE2@1|root,32QTW@2|Bacteria,1VD6K@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02110	457412.RSAG_00992	1.31e-303	831.0	COG0534@1|root,COG0534@2|Bacteria,1TRR0@1239|Firmicutes,249UC@186801|Clostridia,3WGYY@541000|Ruminococcaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_02111	1226325.HMPREF1548_03503	9.37e-155	439.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,36FMD@31979|Clostridiaceae	186801|Clostridia	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
PKFBPKFJ_02112	457412.RSAG_01007	5.25e-116	335.0	2BVMK@1|root,32QXV@2|Bacteria,1V9D0@1239|Firmicutes,24K6Z@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
PKFBPKFJ_02114	1280698.AUJS01000058_gene1883	1.97e-131	385.0	COG4942@1|root,COG4942@2|Bacteria,1V67C@1239|Firmicutes,25FCI@186801|Clostridia,27XE4@189330|Dorea	186801|Clostridia	D	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
PKFBPKFJ_02115	457412.RSAG_03499	0.0	867.0	COG3385@1|root,COG3385@2|Bacteria,1UZFU@1239|Firmicutes,25CHJ@186801|Clostridia,3WSD2@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PKFBPKFJ_02116	457412.RSAG_02590	6.79e-65	197.0	COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,24NM2@186801|Clostridia,3WRA2@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR associated protein Cas2	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
PKFBPKFJ_02117	457412.RSAG_02591	4.13e-99	287.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1,RVT_1
PKFBPKFJ_02118	457412.RSAG_02592	0.0	906.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,3WGY1@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR-associated helicase, Cas3	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
PKFBPKFJ_02119	457412.RSAG_02592	5.57e-280	785.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,3WGY1@541000|Ruminococcaceae	186801|Clostridia	L	CRISPR-associated helicase, Cas3	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
PKFBPKFJ_02120	457412.RSAG_02593	1.69e-178	496.0	28NN3@1|root,2ZBNI@2|Bacteria,1V27F@1239|Firmicutes,24G81@186801|Clostridia	186801|Clostridia	S	CRISPR-associated protein Cas5	cas5h	-	-	ko:K19116	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
PKFBPKFJ_02121	457412.RSAG_02594	1.17e-186	521.0	COG3649@1|root,COG3649@2|Bacteria,1UKQK@1239|Firmicutes,24C9C@186801|Clostridia	186801|Clostridia	L	CRISPR-associated protein Cas7	-	-	-	ko:K19115	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas7
PKFBPKFJ_02122	457412.RSAG_02595	0.0	1168.0	28JMD@1|root,2Z9DX@2|Bacteria,1UM68@1239|Firmicutes,24CYH@186801|Clostridia	186801|Clostridia	-	-	csh	-	-	ko:K19114	-	-	-	-	ko00000,ko02048	-	-	-	-
PKFBPKFJ_02123	457412.RSAG_02596	5.26e-172	479.0	COG1583@1|root,COG1583@2|Bacteria,1V4U6@1239|Firmicutes,24EJT@186801|Clostridia	186801|Clostridia	L	CRISPR associated protein Cas6	cas6	-	-	ko:K19091	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas6
PKFBPKFJ_02124	457412.RSAG_02597	0.0	1209.0	COG0426@1|root,COG1773@1|root,COG1853@1|root,COG0426@2|Bacteria,COG1773@2|Bacteria,COG1853@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
PKFBPKFJ_02125	457412.RSAG_02598	2.52e-282	771.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,3WIXP@541000|Ruminococcaceae	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
PKFBPKFJ_02126	1121115.AXVN01000089_gene2819	0.0	1247.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,3XYQ1@572511|Blautia	186801|Clostridia	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
PKFBPKFJ_02127	1121115.AXVN01000089_gene2818	9.23e-207	573.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia,3Y072@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
PKFBPKFJ_02128	457412.RSAG_04618	0.0	1882.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WGVD@541000|Ruminococcaceae	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg,SBP_bac_3
PKFBPKFJ_02129	1121115.AXVN01000089_gene2816	0.0	1228.0	COG0737@1|root,COG1653@1|root,COG0737@2|Bacteria,COG1653@2|Bacteria,1U6YH@1239|Firmicutes,24ENB@186801|Clostridia,3Y15J@572511|Blautia	186801|Clostridia	FG	ABC transporter substrate-binding protein	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SBP_bac_1,SBP_bac_8
PKFBPKFJ_02130	1121115.AXVN01000089_gene2815	0.0	1370.0	COG0642@1|root,COG0784@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia,3Y1FS@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
PKFBPKFJ_02131	457412.RSAG_02604	2.15e-194	539.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3WH7X@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
PKFBPKFJ_02132	1121115.AXVN01000089_gene2813	3.24e-308	842.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYX6@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_02133	1121115.AXVN01000089_gene2812	1.35e-102	297.0	COG1522@1|root,COG1522@2|Bacteria,1V1DR@1239|Firmicutes,25DYB@186801|Clostridia,3Y283@572511|Blautia	186801|Clostridia	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
PKFBPKFJ_02134	411459.RUMOBE_01480	2.15e-240	660.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,247UN@186801|Clostridia,3XZV8@572511|Blautia	186801|Clostridia	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02135	457412.RSAG_02443	2.46e-219	604.0	COG0846@1|root,COG0846@2|Bacteria,1V192@1239|Firmicutes,24ERM@186801|Clostridia,3WIPW@541000|Ruminococcaceae	186801|Clostridia	K	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02136	1280698.AUJS01000042_gene3263	7.35e-99	287.0	COG1959@1|root,COG1959@2|Bacteria,1V34F@1239|Firmicutes,24H42@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
PKFBPKFJ_02137	457412.RSAG_02441	3.72e-65	199.0	2EIVT@1|root,33CM3@2|Bacteria,1UKI7@1239|Firmicutes,25FXR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02138	457412.RSAG_02440	1.54e-56	176.0	COG3077@1|root,COG3077@2|Bacteria,1VABY@1239|Firmicutes,24PQZ@186801|Clostridia,3WKWU@541000|Ruminococcaceae	186801|Clostridia	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
PKFBPKFJ_02139	457412.RSAG_02439	2.6e-63	193.0	COG3041@1|root,COG3041@2|Bacteria,1TUTV@1239|Firmicutes,25NAT@186801|Clostridia,3WQD7@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial toxin of type II toxin-antitoxin system, YafQ	-	-	-	ko:K19157	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YafQ_toxin
PKFBPKFJ_02140	457412.RSAG_04637	2.54e-42	139.0	2EA3V@1|root,3348U@2|Bacteria,1VFVI@1239|Firmicutes,24RVZ@186801|Clostridia,3WQVA@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02141	457412.RSAG_02437	3.84e-90	263.0	COG0454@1|root,COG0456@2|Bacteria,1V239@1239|Firmicutes,24IE6@186801|Clostridia,3WKTE@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
PKFBPKFJ_02142	457412.RSAG_02436	0.0	1551.0	COG0577@1|root,COG0577@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,3WHE4@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PKFBPKFJ_02143	1280698.AUJS01000027_gene2301	5.64e-153	430.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,27W3S@189330|Dorea	186801|Clostridia	V	COG COG1136 ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_02144	1121115.AXVN01000004_gene1967	2.31e-95	278.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,3Y024@572511|Blautia	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
PKFBPKFJ_02145	1121115.AXVN01000004_gene1968	1.37e-127	362.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,3Y04A@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
PKFBPKFJ_02146	1121115.AXVN01000004_gene1969	0.0	1833.0	COG0419@1|root,COG0419@2|Bacteria,1TPCS@1239|Firmicutes,24A22@186801|Clostridia,3XZKX@572511|Blautia	186801|Clostridia	L	Psort location	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,AAA_29,SbcCD_C
PKFBPKFJ_02147	457412.RSAG_00403	6.5e-268	734.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,3WH9B@541000|Ruminococcaceae	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
PKFBPKFJ_02148	1121115.AXVN01000004_gene1972	1.32e-167	469.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,3XYWN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
PKFBPKFJ_02149	1121115.AXVN01000004_gene1973	3.46e-54	169.0	COG1925@1|root,COG1925@2|Bacteria,1VE7N@1239|Firmicutes,24Q2D@186801|Clostridia,3Y0JB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	ptsH	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
PKFBPKFJ_02150	1121115.AXVN01000004_gene1974	0.0	1187.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,3XZB2@572511|Blautia	186801|Clostridia	GT	Psort location CytoplasmicMembrane, score 10.00	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
PKFBPKFJ_02151	1121115.AXVN01000004_gene1975	1.12e-212	588.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,3XZ0R@572511|Blautia	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
PKFBPKFJ_02152	1121115.AXVN01000004_gene1976	0.0	900.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
PKFBPKFJ_02153	1121115.AXVN01000004_gene1977	0.0	1105.0	COG1775@1|root,COG1924@1|root,COG1775@2|Bacteria,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,3Y04S@572511|Blautia	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	hgdC_1	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,HGD-D
PKFBPKFJ_02154	1121115.AXVN01000004_gene1978	3.79e-314	855.0	COG1775@1|root,COG1775@2|Bacteria,1TS7H@1239|Firmicutes,2493U@186801|Clostridia,3Y0V9@572511|Blautia	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
PKFBPKFJ_02155	1121115.AXVN01000004_gene1979	0.0	1102.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XYTP@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PKFBPKFJ_02156	1121115.AXVN01000004_gene1980	0.0	1116.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XYGZ@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PKFBPKFJ_02157	457412.RSAG_00413	0.0	1202.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,3WHK3@541000|Ruminococcaceae	186801|Clostridia	E	Creatinase/Prolidase N-terminal domain	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
PKFBPKFJ_02158	1121115.AXVN01000004_gene1982	9.86e-201	556.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,3Y0BE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,NAD_synthase,QueC
PKFBPKFJ_02159	1121115.AXVN01000004_gene1983	1.83e-188	523.0	COG2207@1|root,COG2207@2|Bacteria,1TXIY@1239|Firmicutes,248D1@186801|Clostridia,3Y2AU@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PKFBPKFJ_02160	1121115.AXVN01000004_gene1984	0.0	910.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3XZZ6@572511|Blautia	186801|Clostridia	G	MFS/sugar transport protein	uidB_2	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
PKFBPKFJ_02161	457412.RSAG_00417	0.0	2097.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3WGCC@541000|Ruminococcaceae	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PKFBPKFJ_02162	457412.RSAG_00418	2.27e-213	588.0	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,3WGYB@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	araC_2	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
PKFBPKFJ_02163	457412.RSAG_00419	7.39e-132	374.0	COG4636@1|root,COG4636@2|Bacteria,1V8DJ@1239|Firmicutes,24G93@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
PKFBPKFJ_02164	457412.RSAG_00420	5.1e-123	350.0	COG4636@1|root,COG4636@2|Bacteria,1V5WZ@1239|Firmicutes,24IWJ@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
PKFBPKFJ_02165	1121115.AXVN01000020_gene100	3.38e-17	75.1	COG3077@1|root,COG3077@2|Bacteria,1VJC4@1239|Firmicutes,25CY3@186801|Clostridia	186801|Clostridia	L	RelB antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	RelB
PKFBPKFJ_02166	511680.BUTYVIB_01914	9.55e-06	45.8	2E4DC@1|root,32Z8R@2|Bacteria,1VF6A@1239|Firmicutes,24QX7@186801|Clostridia,4C00Y@830|Butyrivibrio	186801|Clostridia	S	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	ko:K19165	-	-	-	-	ko00000,ko02048	-	-	-	PhdYeFM_antitox
PKFBPKFJ_02167	457412.RSAG_00423	1.82e-130	370.0	COG4636@1|root,COG4636@2|Bacteria,1V1Q1@1239|Firmicutes,24ITV@186801|Clostridia,3WS1U@541000|Ruminococcaceae	1239|Firmicutes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
PKFBPKFJ_02169	411469.EUBHAL_01479	3.79e-31	116.0	COG3153@1|root,COG3153@2|Bacteria,1V3PW@1239|Firmicutes,24ACS@186801|Clostridia,25W14@186806|Eubacteriaceae	186801|Clostridia	S	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
PKFBPKFJ_02170	411469.EUBHAL_01478	2.12e-43	146.0	COG1309@1|root,COG1309@2|Bacteria,1V5EA@1239|Firmicutes,25BHW@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	mtrR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PKFBPKFJ_02171	457412.RSAG_03502	4.13e-294	805.0	COG2826@1|root,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,3WIJ3@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
PKFBPKFJ_02172	457412.RSAG_01439	0.0	1664.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3WH8W@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PKFBPKFJ_02173	411473.RUMCAL_02057	5.5e-146	414.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WG7X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_02174	483218.BACPEC_00281	9.62e-180	504.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,268Z5@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_02175	483218.BACPEC_00282	1.91e-151	427.0	COG0745@1|root,COG0745@2|Bacteria,1TSNV@1239|Firmicutes,2493A@186801|Clostridia,268X2@186813|unclassified Clostridiales	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_02176	411460.RUMTOR_00623	2.32e-77	231.0	29RZY@1|root,30D49@2|Bacteria,1V3IV@1239|Firmicutes,24M5F@186801|Clostridia,3Y1P7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02177	411470.RUMGNA_03244	4.8e-58	181.0	2DVAH@1|root,32UZ0@2|Bacteria,1VMS9@1239|Firmicutes,24IP4@186801|Clostridia,3Y09C@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
PKFBPKFJ_02178	411469.EUBHAL_02613	7.04e-71	216.0	28NY7@1|root,2ZBVG@2|Bacteria,1V2J3@1239|Firmicutes,24G35@186801|Clostridia,25WT4@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF2992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2992
PKFBPKFJ_02180	1235800.C819_01275	2.32e-226	646.0	COG1384@1|root,COG1384@2|Bacteria,1VG2Y@1239|Firmicutes,24SBF@186801|Clostridia	186801|Clostridia	J	Domain of unknown function (DUF4209)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4209
PKFBPKFJ_02181	411459.RUMOBE_03504	3.08e-287	790.0	2CGG8@1|root,30FQ1@2|Bacteria,1UEDU@1239|Firmicutes,25JA2@186801|Clostridia,3Y0ZN@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02182	411459.RUMOBE_03505	1.18e-261	721.0	COG0642@1|root,COG2205@2|Bacteria,1TRD2@1239|Firmicutes,247M3@186801|Clostridia,3Y0A6@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PKFBPKFJ_02183	411459.RUMOBE_03506	1.88e-144	408.0	COG0745@1|root,COG0745@2|Bacteria,1TT73@1239|Firmicutes,25BHU@186801|Clostridia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_02184	457412.RSAG_00432	2.05e-76	231.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WRUB@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_02185	457412.RSAG_00431	1.18e-210	597.0	2E6HB@1|root,3314J@2|Bacteria,1VGBM@1239|Firmicutes,24T1M@186801|Clostridia,3WMCU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02186	457412.RSAG_00433	0.0	1048.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,24A30@186801|Clostridia,3WJX1@541000|Ruminococcaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
PKFBPKFJ_02187	457412.RSAG_00434	1.62e-83	247.0	COG3682@1|root,COG3682@2|Bacteria,1VEJ8@1239|Firmicutes,24R6S@186801|Clostridia,3WKEQ@541000|Ruminococcaceae	186801|Clostridia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
PKFBPKFJ_02188	457412.RSAG_00435	1.8e-170	479.0	2EYFT@1|root,33RPP@2|Bacteria,1VSB0@1239|Firmicutes,24XZU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02189	457412.RSAG_00468	1.04e-46	151.0	COG0784@1|root,COG0784@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
PKFBPKFJ_02190	457412.RSAG_00469	6.24e-119	350.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24FCE@186801|Clostridia,3WP1Z@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605
PKFBPKFJ_02191	457412.RSAG_00469	7.19e-179	505.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24FCE@186801|Clostridia,3WP1Z@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605
PKFBPKFJ_02192	457412.RSAG_00470	1.51e-93	273.0	COG1943@1|root,COG1943@2|Bacteria,1VAIQ@1239|Firmicutes,24IPG@186801|Clostridia,3WRVG@541000|Ruminococcaceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
PKFBPKFJ_02194	457412.RSAG_02518	4.77e-228	651.0	COG1554@1|root,COG1554@2|Bacteria,1TPKN@1239|Firmicutes,248K8@186801|Clostridia,3WH2C@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 65, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Dockerin_1,F5_F8_type_C,Glyco_hyd_65N_2
PKFBPKFJ_02195	97139.C824_00763	5.34e-91	288.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UYK2@1239|Firmicutes,247MJ@186801|Clostridia,36H9A@31979|Clostridiaceae	186801|Clostridia	T	response regulator, receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
PKFBPKFJ_02196	1280698.AUJS01000002_gene2691	0.0	1458.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,27W2S@189330|Dorea	186801|Clostridia	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PKFBPKFJ_02197	1280698.AUJS01000072_gene193	2.87e-117	344.0	COG2207@1|root,COG2207@2|Bacteria,1TXIY@1239|Firmicutes,248D1@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
PKFBPKFJ_02198	457412.RSAG_00486	8.04e-257	705.0	2ACB9@1|root,311W7@2|Bacteria,1V49X@1239|Firmicutes,24NF4@186801|Clostridia,3WJZP@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
PKFBPKFJ_02199	457412.RSAG_00487	3.39e-121	346.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WJQH@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_02200	457412.RSAG_00488	5.24e-196	544.0	2FCDN@1|root,344H7@2|Bacteria,1W31R@1239|Firmicutes,256SW@186801|Clostridia	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02201	457412.RSAG_00490	1.81e-127	362.0	COG2755@1|root,COG2755@2|Bacteria,1V18W@1239|Firmicutes,24DIM@186801|Clostridia,3WP3Z@541000|Ruminococcaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PKFBPKFJ_02202	457412.RSAG_00491	1.77e-125	357.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,3WH35@541000|Ruminococcaceae	186801|Clostridia	T	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF1768,Macro
PKFBPKFJ_02203	457412.RSAG_00493	1.02e-192	538.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
PKFBPKFJ_02204	457412.RSAG_00494	7.11e-172	480.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3WGT4@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS2 family	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
PKFBPKFJ_02205	1121115.AXVN01000026_gene995	9.67e-174	485.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,3XZSS@572511|Blautia	186801|Clostridia	J	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
PKFBPKFJ_02206	457412.RSAG_00496	0.0	1316.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,24EMN@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
PKFBPKFJ_02207	1121115.AXVN01000026_gene993	1.94e-216	597.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia,3XYHB@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	ytrB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_02208	1121115.AXVN01000026_gene992	2.53e-80	238.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia,3Y09K@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
PKFBPKFJ_02209	1121115.AXVN01000026_gene991	4.37e-166	466.0	COG1266@1|root,COG1266@2|Bacteria,1W749@1239|Firmicutes,25MB2@186801|Clostridia,3Y0CJ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Abi
PKFBPKFJ_02210	1121115.AXVN01000026_gene990	2.71e-151	425.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,3XZY6@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
PKFBPKFJ_02211	457412.RSAG_00501	7.74e-121	358.0	2CAM6@1|root,33TP6@2|Bacteria,1VTBW@1239|Firmicutes,24Z6R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02212	457412.RSAG_00502	1.52e-300	820.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,3WIN0@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
PKFBPKFJ_02213	1121115.AXVN01000026_gene987	0.0	1163.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,3XZ10@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
PKFBPKFJ_02214	457412.RSAG_00504	7.78e-202	559.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,248N9@186801|Clostridia,3WGV0@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
PKFBPKFJ_02215	1121115.AXVN01000026_gene985	0.0	1016.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3XZ65@572511|Blautia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
PKFBPKFJ_02216	1121115.AXVN01000026_gene984	2.97e-54	169.0	COG1925@1|root,COG1925@2|Bacteria	2|Bacteria	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	ptsH	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
PKFBPKFJ_02217	1121115.AXVN01000026_gene983	1.88e-290	794.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3XZ33@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PKFBPKFJ_02218	1121115.AXVN01000029_gene630	0.0	1242.0	COG0845@1|root,COG0845@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia,3XYTA@572511|Blautia	186801|Clostridia	M	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
PKFBPKFJ_02219	457412.RSAG_00509	7.73e-155	435.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3WGVE@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_02220	457412.RSAG_00510	9.91e-307	842.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia,3WI4Z@541000|Ruminococcaceae	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
PKFBPKFJ_02221	457412.RSAG_00511	3.13e-274	752.0	COG2247@1|root,COG2247@2|Bacteria,1TUN7@1239|Firmicutes,24Y24@186801|Clostridia,3WMU5@541000|Ruminococcaceae	186801|Clostridia	M	cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02222	1121115.AXVN01000029_gene634	4.97e-170	476.0	COG0730@1|root,COG0730@2|Bacteria,1TQBK@1239|Firmicutes,24A0G@186801|Clostridia,3XZD6@572511|Blautia	186801|Clostridia	S	Sulfite exporter TauE/SafE	yfcA	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
PKFBPKFJ_02223	1121115.AXVN01000029_gene635	0.0	1172.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,3XZ1M@572511|Blautia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
PKFBPKFJ_02224	1121115.AXVN01000029_gene636	4.11e-293	800.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,3XYX1@572511|Blautia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
PKFBPKFJ_02225	457412.RSAG_00515	8.1e-160	447.0	COG2206@1|root,COG2206@2|Bacteria,1V54U@1239|Firmicutes,24HUA@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HD,HD_5
PKFBPKFJ_02226	457412.RSAG_00516	0.0	1003.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,3WGA8@541000|Ruminococcaceae	186801|Clostridia	C	Coproporphyrinogen dehydrogenase	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
PKFBPKFJ_02227	457412.RSAG_00517	4.55e-156	437.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,3WJD3@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PKFBPKFJ_02228	1121115.AXVN01000029_gene640	0.0	1503.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,3XZ3M@572511|Blautia	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
PKFBPKFJ_02229	1121115.AXVN01000029_gene641	4.17e-119	340.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,3XZ59@572511|Blautia	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
PKFBPKFJ_02230	1121115.AXVN01000029_gene642	0.0	1120.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3XZHQ@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
PKFBPKFJ_02231	1121115.AXVN01000029_gene643	0.0	1439.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,3XYSY@572511|Blautia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
PKFBPKFJ_02232	1121115.AXVN01000029_gene644	0.0	943.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,3XZ42@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
PKFBPKFJ_02233	1121115.AXVN01000029_gene645	1.83e-20	81.6	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,3Y0JJ@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score 8.82	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
PKFBPKFJ_02234	1121115.AXVN01000029_gene646	8.43e-73	219.0	2E3KV@1|root,32YJ5@2|Bacteria,1VEHD@1239|Firmicutes,24RP3@186801|Clostridia,3Y0RE@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
PKFBPKFJ_02235	1121115.AXVN01000029_gene647	9.37e-259	720.0	2ENTE@1|root,33GEK@2|Bacteria,1VSB4@1239|Firmicutes,24YR1@186801|Clostridia,3XZII@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02236	1121115.AXVN01000029_gene648	2.26e-286	785.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3XZS0@572511|Blautia	186801|Clostridia	S	COG COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
PKFBPKFJ_02237	457412.RSAG_00527	2.54e-144	406.0	COG1434@1|root,COG1434@2|Bacteria,1V32X@1239|Firmicutes,24ATY@186801|Clostridia,3WITP@541000|Ruminococcaceae	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
PKFBPKFJ_02238	1121115.AXVN01000029_gene650	7.21e-76	233.0	COG0860@1|root,COG0860@2|Bacteria,1TS91@1239|Firmicutes,25B1N@186801|Clostridia,3XZHM@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	cwlC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SPOR
PKFBPKFJ_02239	1235799.C818_01822	0.0	934.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27J46@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_02240	411461.DORFOR_03074	3.68e-45	146.0	2AWCN@1|root,31N8H@2|Bacteria,1V7KM@1239|Firmicutes,24U8N@186801|Clostridia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
PKFBPKFJ_02241	411461.DORFOR_03075	8.75e-90	263.0	COG1191@1|root,COG1191@2|Bacteria,1UJ7B@1239|Firmicutes,24KND@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sigma70_r4_2
PKFBPKFJ_02242	1504823.CCMM01000012_gene2062	2.21e-69	210.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_02243	1235799.C818_00074	8.27e-35	119.0	2DP5Q@1|root,330MY@2|Bacteria,1VFAQ@1239|Firmicutes,24R7E@186801|Clostridia,27PN8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Cysteine-rich KTR	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_KTR
PKFBPKFJ_02244	1235799.C818_00075	8.43e-277	763.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,27J9K@186928|unclassified Lachnospiraceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_02245	1235799.C818_00076	8.18e-102	297.0	COG1695@1|root,COG1695@2|Bacteria,1V1R5@1239|Firmicutes,24FU3@186801|Clostridia,27MDD@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34,PadR,Vir_act_alpha_C
PKFBPKFJ_02246	1235790.C805_02656	2.57e-35	130.0	2DPZV@1|root,3344W@2|Bacteria,1VJXN@1239|Firmicutes,24RIB@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
PKFBPKFJ_02247	397288.C806_03319	5.09e-168	473.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,27IKW@186928|unclassified Lachnospiraceae	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PKFBPKFJ_02248	397288.C806_03320	2.16e-72	218.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24I83@186801|Clostridia,27N00@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, gntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
PKFBPKFJ_02249	411461.DORFOR_03082	1.23e-199	555.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,27W11@189330|Dorea	186801|Clostridia	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
PKFBPKFJ_02250	411461.DORFOR_03083	4.57e-223	617.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia,27WJ1@189330|Dorea	186801|Clostridia	M	Lysozyme-like	-	-	-	-	-	-	-	-	-	-	-	-	Lysozyme_like,NLPC_P60
PKFBPKFJ_02251	411461.DORFOR_03084	0.0	986.0	COG3064@1|root,COG3064@2|Bacteria,1UIYZ@1239|Firmicutes,249MX@186801|Clostridia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02252	411461.DORFOR_03085	0.0	1554.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,24AAP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
PKFBPKFJ_02253	411463.EUBVEN_01745	1.97e-84	249.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,24FQV@186801|Clostridia,25WAF@186806|Eubacteriaceae	186801|Clostridia	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
PKFBPKFJ_02254	411463.EUBVEN_01746	2.67e-116	332.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,25WNI@186806|Eubacteriaceae	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
PKFBPKFJ_02255	411461.DORFOR_03088	8.63e-117	334.0	COG4734@1|root,COG4734@2|Bacteria,1VHFX@1239|Firmicutes,24QQM@186801|Clostridia	186801|Clostridia	S	COG NOG09588 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
PKFBPKFJ_02256	411461.DORFOR_03089	5.05e-55	171.0	2AJ8P@1|root,319TK@2|Bacteria,1V9F5@1239|Firmicutes,24KKK@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02257	397287.C807_01987	2.71e-101	300.0	2DC2A@1|root,2ZCM4@2|Bacteria,1V953@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02258	1235798.C817_01438	4.86e-27	99.8	2EKT5@1|root,33EGW@2|Bacteria,1W392@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02259	641107.CDLVIII_5801	3.41e-41	135.0	2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,24N4I@186801|Clostridia,36KXQ@31979|Clostridiaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02261	411461.DORFOR_03092	3.82e-296	811.0	COG3620@1|root,COG3620@2|Bacteria,1TPHQ@1239|Firmicutes,249PB@186801|Clostridia,27XDR@189330|Dorea	186801|Clostridia	K	Replication initiation factor	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Rep_trans
PKFBPKFJ_02262	411461.DORFOR_03093	0.0	886.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,27V96@189330|Dorea	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,FtsK_SpoIIIE
PKFBPKFJ_02264	411461.DORFOR_03094	7.35e-80	238.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,24IAF@186801|Clostridia,27XB2@189330|Dorea	186801|Clostridia	S	COG NOG13239 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
PKFBPKFJ_02265	411461.DORFOR_03095	1.63e-67	206.0	2BXTH@1|root,2ZZ52@2|Bacteria,1V3TU@1239|Firmicutes,24I3V@186801|Clostridia,27X3K@189330|Dorea	186801|Clostridia	S	COG NOG10998 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
PKFBPKFJ_02266	411461.DORFOR_03096	0.0	1946.0	COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia,27WEU@189330|Dorea	186801|Clostridia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02267	1121115.AXVN01000029_gene651	1.49e-225	622.0	COG2984@1|root,COG2984@2|Bacteria,1TPB0@1239|Firmicutes,248X3@186801|Clostridia,3XZPA@572511|Blautia	186801|Clostridia	S	ABC transporter substrate binding protein	-	-	-	ko:K01989	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_sub_bind
PKFBPKFJ_02268	1121115.AXVN01000029_gene652	3.52e-201	559.0	COG4120@1|root,COG4120@2|Bacteria,1TPDJ@1239|Firmicutes,249P1@186801|Clostridia,3XZ3B@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K05832	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	BPD_transp_2
PKFBPKFJ_02269	1121115.AXVN01000029_gene653	6.03e-177	494.0	COG1101@1|root,COG1101@2|Bacteria,1TPAN@1239|Firmicutes,247WW@186801|Clostridia,3XZ9G@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K05833	-	M00247	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
PKFBPKFJ_02270	1121115.AXVN01000029_gene654	3.43e-234	643.0	2EWQA@1|root,33TE1@2|Bacteria,1VR3E@1239|Firmicutes,24ZHT@186801|Clostridia,3Y1M8@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02271	457412.RSAG_00533	6.87e-117	333.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,3WIXC@541000|Ruminococcaceae	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
PKFBPKFJ_02272	457412.RSAG_00534	6.52e-290	791.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3WH9S@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
PKFBPKFJ_02273	1121115.AXVN01000053_gene1863	1.89e-51	162.0	2CCB2@1|root,30HYC@2|Bacteria,1W7AC@1239|Firmicutes,25N1I@186801|Clostridia,3Y25P@572511|Blautia	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
PKFBPKFJ_02274	1121115.AXVN01000053_gene1862	0.0	903.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,3XYY4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	VirE
PKFBPKFJ_02275	1121115.AXVN01000053_gene1861	8.75e-152	426.0	COG0358@1|root,COG0358@2|Bacteria,1TRW1@1239|Firmicutes,249RY@186801|Clostridia,3XZM5@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
PKFBPKFJ_02276	1121115.AXVN01000053_gene1860	0.0	1027.0	COG0507@1|root,COG1196@1|root,COG0507@2|Bacteria,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,3XYKV@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PKFBPKFJ_02277	397290.C810_01111	2.64e-60	189.0	28PAQ@1|root,2ZC3T@2|Bacteria,1V53M@1239|Firmicutes,24Q7S@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02278	397290.C810_01112	2.44e-36	123.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QPB@186801|Clostridia,27Q6X@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
PKFBPKFJ_02279	411471.SUBVAR_06054	5.77e-58	180.0	2B26K@1|root,31UPX@2|Bacteria,1V93Z@1239|Firmicutes,24JA0@186801|Clostridia,3WJCW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
PKFBPKFJ_02280	1235798.C817_01260	3.48e-75	224.0	COG1349@1|root,COG1349@2|Bacteria,1V4EI@1239|Firmicutes,24HRM@186801|Clostridia,27WVB@189330|Dorea	186801|Clostridia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_DeoR
PKFBPKFJ_02281	552398.HMPREF0866_02061	3.62e-38	127.0	2CBNR@1|root,32T16@2|Bacteria,1VA97@1239|Firmicutes,24NAW@186801|Clostridia,3WJUG@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02282	1121115.AXVN01000053_gene1855	1.23e-187	521.0	COG1396@1|root,COG1396@2|Bacteria,1TT2N@1239|Firmicutes,2488F@186801|Clostridia,3XZPN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PKFBPKFJ_02283	1121115.AXVN01000053_gene1854	1.63e-148	418.0	28J9U@1|root,2Z94P@2|Bacteria,1UYN9@1239|Firmicutes,248AD@186801|Clostridia,3Y1RV@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02284	411483.FAEPRAA2165_00889	3.88e-146	411.0	COG3340@1|root,COG3340@2|Bacteria,1V7DK@1239|Firmicutes,24D9U@186801|Clostridia,3WR1Q@541000|Ruminococcaceae	186801|Clostridia	E	Peptidase family S51	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S51
PKFBPKFJ_02285	1121115.AXVN01000053_gene1851	9.8e-64	197.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,25CQN@186801|Clostridia,3Y2CW@572511|Blautia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PKFBPKFJ_02286	411459.RUMOBE_00571	8.55e-38	132.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3XZ4E@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_integrase
PKFBPKFJ_02287	457412.RSAG_04775	0.0	901.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24FCE@186801|Clostridia,3WP1Z@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605
PKFBPKFJ_02288	457412.RSAG_02808	0.0	1140.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	DUF4157,Flg_new,LRR_5,TcdB_toxin_midN
PKFBPKFJ_02290	457412.RSAG_02810	1.95e-221	610.0	COG0791@1|root,COG0791@2|Bacteria,1V9RT@1239|Firmicutes,24EYR@186801|Clostridia,3WJFG@541000|Ruminococcaceae	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_5,NLPC_P60,PG_binding_1
PKFBPKFJ_02291	457412.RSAG_02811	5.61e-71	214.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
PKFBPKFJ_02292	1121115.AXVN01000051_gene811	2.11e-76	234.0	2EHNM@1|root,33BEE@2|Bacteria,1VNIH@1239|Firmicutes,24PUV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02293	457412.RSAG_02813	8.64e-163	456.0	COG3279@1|root,COG3279@2|Bacteria,1UYV2@1239|Firmicutes,25KED@186801|Clostridia,3WM6U@541000|Ruminococcaceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_02294	457412.RSAG_02814	0.0	948.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,24JUC@186801|Clostridia,3WJ4K@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PKFBPKFJ_02296	457412.RSAG_02815	0.0	1781.0	COG4403@1|root,COG4403@2|Bacteria,1TS6F@1239|Firmicutes,247JU@186801|Clostridia,3WIW0@541000|Ruminococcaceae	186801|Clostridia	V	Lanthionine synthetase C-like protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4135,LANC_like
PKFBPKFJ_02297	457412.RSAG_02816	5.47e-125	355.0	2EGBC@1|root,33A36@2|Bacteria,1UKIB@1239|Firmicutes,24VNX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02298	457412.RSAG_02817	4.38e-43	140.0	2E98V@1|root,333H5@2|Bacteria,1VI8K@1239|Firmicutes,24RMD@186801|Clostridia	186801|Clostridia	S	BhlA holin family	-	-	-	-	-	-	-	-	-	-	-	-	Holin_BhlA
PKFBPKFJ_02299	457412.RSAG_02818	0.0	1390.0	COG5492@1|root,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Polysacc_lyase,SLH
PKFBPKFJ_02300	457412.RSAG_02452	2.11e-18	84.7	2DUPK@1|root,33RK6@2|Bacteria,1VRQV@1239|Firmicutes,24YX7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02301	457412.RSAG_02820	3.82e-167	467.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3WG98@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_02302	457412.RSAG_02821	0.0	1617.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,3WGNX@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PKFBPKFJ_02303	457412.RSAG_02822	1.58e-307	836.0	COG2159@1|root,COG2159@2|Bacteria,1UZI6@1239|Firmicutes,24EHD@186801|Clostridia,3WKR9@541000|Ruminococcaceae	186801|Clostridia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
PKFBPKFJ_02304	1121115.AXVN01000057_gene2519	0.0	1808.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3XYWB@572511|Blautia	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
PKFBPKFJ_02305	457412.RSAG_02825	0.0	1358.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,3WSDQ@541000|Ruminococcaceae	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
PKFBPKFJ_02306	457412.RSAG_02826	8.66e-316	859.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3WGW8@541000|Ruminococcaceae	186801|Clostridia	H	Mur ligase middle domain	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
PKFBPKFJ_02307	1121115.AXVN01000057_gene2522	3.2e-27	99.0	2EGDA@1|root,33A54@2|Bacteria,1VKC8@1239|Firmicutes,258G8@186801|Clostridia,3Y0SU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02308	457412.RSAG_02828	3.69e-262	725.0	COG0457@1|root,COG0457@2|Bacteria,1UI34@1239|Firmicutes,25F0K@186801|Clostridia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_11,TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
PKFBPKFJ_02309	1121115.AXVN01000057_gene2524	2.76e-70	211.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,3Y0KP@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
PKFBPKFJ_02310	1121115.AXVN01000057_gene2525	1.5e-96	281.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,3Y0A1@572511|Blautia	186801|Clostridia	H	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
PKFBPKFJ_02311	1121115.AXVN01000057_gene2526	4.08e-157	442.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia,3XZEX@572511|Blautia	186801|Clostridia	K	COG COG1191 DNA-directed RNA polymerase specialized sigma subunit	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
PKFBPKFJ_02313	457412.RSAG_02832	1.72e-109	315.0	COG4708@1|root,COG4708@2|Bacteria,1V9YK@1239|Firmicutes,24N9H@186801|Clostridia,3WKVC@541000|Ruminococcaceae	186801|Clostridia	S	QueT transporter	queT	-	-	-	-	-	-	-	-	-	-	-	QueT
PKFBPKFJ_02314	1121115.AXVN01000065_gene680	8.86e-35	119.0	2CHQ1@1|root,3240C@2|Bacteria,1UQE2@1239|Firmicutes,25855@186801|Clostridia,3Y1Z3@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02315	411489.CLOL250_01657	2.73e-75	226.0	2C5R4@1|root,32R5C@2|Bacteria,1V57Y@1239|Firmicutes,24HAA@186801|Clostridia,36VZ3@31979|Clostridiaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PKFBPKFJ_02316	411489.CLOL250_01656	1.53e-110	334.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,36KE8@31979|Clostridiaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PKFBPKFJ_02317	411489.CLOL250_01656	9.86e-128	375.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,36KE8@31979|Clostridiaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PKFBPKFJ_02318	411489.CLOL250_01655	1.69e-51	162.0	2DQEK@1|root,32UNY@2|Bacteria,1VCGS@1239|Firmicutes,24MR4@186801|Clostridia,36TY6@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF5348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
PKFBPKFJ_02319	411489.CLOL250_01654	4.9e-42	138.0	2CIZU@1|root,3323B@2|Bacteria,1VF1D@1239|Firmicutes,24QPV@186801|Clostridia,36T49@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02320	411489.CLOL250_01653	1.23e-230	635.0	COG1066@1|root,COG1066@2|Bacteria,1UIA9@1239|Firmicutes,25EF9@186801|Clostridia,36UNR@31979|Clostridiaceae	186801|Clostridia	O	DnaB-like helicase C terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
PKFBPKFJ_02321	411489.CLOL250_01652	8.56e-289	789.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,36E23@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_02322	411489.CLOL250_01651	2.33e-34	117.0	2E5UB@1|root,330IM@2|Bacteria,1VFEC@1239|Firmicutes,24R3P@186801|Clostridia,36PEI@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02323	411489.CLOL250_01650	5.19e-141	399.0	COG1396@1|root,COG1396@2|Bacteria,1TQ4Q@1239|Firmicutes,25FKR@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_02324	457412.RSAG_01489	3.22e-289	789.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3WGI1@541000|Ruminococcaceae	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
PKFBPKFJ_02325	457412.RSAG_01490	0.0	1403.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3WGEG@541000|Ruminococcaceae	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
PKFBPKFJ_02326	457412.RSAG_01491	6.62e-105	303.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,3WGPA@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
PKFBPKFJ_02327	1121115.AXVN01000065_gene675	4.34e-90	264.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3XZTZ@572511|Blautia	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
PKFBPKFJ_02328	457412.RSAG_04528	1.62e-26	97.1	298ED@1|root,2ZVJK@2|Bacteria,1W2SQ@1239|Firmicutes,2571M@186801|Clostridia	457412.RSAG_04528|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02329	1121115.AXVN01000068_gene3392	1.48e-225	623.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,3XZ3C@572511|Blautia	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	lytC_3	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
PKFBPKFJ_02330	457412.RSAG_01494	4.73e-209	584.0	COG2367@1|root,COG2367@2|Bacteria	2|Bacteria	V	Beta-lactamase	bla1	-	3.5.2.6	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	M00627,M00628	R06363	RC01499	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Beta-lactamase2
PKFBPKFJ_02331	33035.JPJF01000008_gene1192	6.68e-06	48.1	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3XZ8Q@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
PKFBPKFJ_02332	1121115.AXVN01000068_gene3395	6.59e-295	805.0	2CF3U@1|root,33TFS@2|Bacteria,1VS98@1239|Firmicutes,24YVZ@186801|Clostridia,3XZ6U@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02333	457412.RSAG_01497	2.62e-200	554.0	COG0631@1|root,COG0631@2|Bacteria,1VXKJ@1239|Firmicutes,2522X@186801|Clostridia,3WK7B@541000|Ruminococcaceae	186801|Clostridia	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PP2C,PP2C_2
PKFBPKFJ_02334	457412.RSAG_01498	0.0	1165.0	COG0515@1|root,COG0515@2|Bacteria,1V2ZP@1239|Firmicutes,24G58@186801|Clostridia,3WIKP@541000|Ruminococcaceae	186801|Clostridia	KLT	Protein tyrosine kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF5050,PASTA,Pkinase,SH3_3
PKFBPKFJ_02335	1121115.AXVN01000068_gene3398	0.0	2378.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3XYSW@572511|Blautia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
PKFBPKFJ_02336	457412.RSAG_01500	0.0	2523.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,3WH6H@541000|Ruminococcaceae	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
PKFBPKFJ_02337	1121115.AXVN01000068_gene3400	0.0	1307.0	COG5434@1|root,COG5434@2|Bacteria,1V8MX@1239|Firmicutes,257MV@186801|Clostridia,3Y1ZG@572511|Blautia	186801|Clostridia	M	Periplasmic copper-binding protein (NosD)	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
PKFBPKFJ_02338	1121115.AXVN01000068_gene3401	1.58e-69	211.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3XZZA@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
PKFBPKFJ_02339	457412.RSAG_01503	1.21e-110	318.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3WIH7@541000|Ruminococcaceae	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
PKFBPKFJ_02340	1121115.AXVN01000068_gene3403	6.96e-151	424.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,3XZJ9@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
PKFBPKFJ_02341	1121115.AXVN01000068_gene3404	9.69e-42	136.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia,3Y0J2@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02342	457412.RSAG_01506	3.81e-254	698.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3WIJZ@541000|Ruminococcaceae	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
PKFBPKFJ_02343	457412.RSAG_00977	0.0	1050.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3WH77@541000|Ruminococcaceae	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PKFBPKFJ_02345	457412.RSAG_04697	1.56e-103	298.0	COG4974@1|root,COG4974@2|Bacteria,1TQST@1239|Firmicutes,24PWB@186801|Clostridia,3WMP6@541000|Ruminococcaceae	186801|Clostridia	L	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C
PKFBPKFJ_02346	457412.RSAG_04698	5.28e-68	205.0	COG4974@1|root,COG4974@2|Bacteria,1TQST@1239|Firmicutes,247YT@186801|Clostridia	186801|Clostridia	L	PFAM transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
PKFBPKFJ_02347	411461.DORFOR_03299	3.17e-33	117.0	2DY71@1|root,348FW@2|Bacteria,1VZTR@1239|Firmicutes,254DS@186801|Clostridia,27X18@189330|Dorea	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_02349	457412.RSAG_00973	0.0	896.0	COG3950@1|root,COG3950@2|Bacteria,1TQIC@1239|Firmicutes,24EDD@186801|Clostridia,3WKZ3@541000|Ruminococcaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
PKFBPKFJ_02350	457412.RSAG_00972	2.24e-176	490.0	COG1403@1|root,COG1403@2|Bacteria,1V5ES@1239|Firmicutes,24IDM@186801|Clostridia	186801|Clostridia	V	HNH nucleases	-	-	-	-	-	-	-	-	-	-	-	-	HNH
PKFBPKFJ_02351	457412.RSAG_00971	1.9e-18	75.9	COG1004@1|root,COG1004@2|Bacteria,1W2Q1@1239|Firmicutes,255WP@186801|Clostridia	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02352	457412.RSAG_00970	0.0	1117.0	COG5421@1|root,COG5421@2|Bacteria,1UHBN@1239|Firmicutes,249CH@186801|Clostridia,3WPID@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PKFBPKFJ_02353	457412.RSAG_00969	6.47e-45	145.0	2EJPA@1|root,33DE4@2|Bacteria,1VPMV@1239|Firmicutes,24VGY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02354	1121115.AXVN01000091_gene2616	5.08e-56	183.0	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
PKFBPKFJ_02355	1121115.AXVN01000091_gene2616	2.97e-79	245.0	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
PKFBPKFJ_02356	865861.AZSU01000002_gene2613	4.94e-76	257.0	2C9CN@1|root,2ZFFI@2|Bacteria,1VUK9@1239|Firmicutes,250GY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02358	457412.RSAG_00966	2.23e-297	811.0	2DEDR@1|root,2ZMJC@2|Bacteria,1V31W@1239|Firmicutes,24FHB@186801|Clostridia,3WPN4@541000|Ruminococcaceae	186801|Clostridia	S	Bacteriophage abortive infection AbiH	-	-	-	-	-	-	-	-	-	-	-	-	AbiH
PKFBPKFJ_02359	457412.RSAG_00965	0.0	1373.0	COG3972@1|root,COG3972@2|Bacteria,1U80C@1239|Firmicutes,24EBG@186801|Clostridia,3WKQH@541000|Ruminococcaceae	186801|Clostridia	S	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
PKFBPKFJ_02360	457412.RSAG_00964	1.84e-159	446.0	COG5619@1|root,COG5619@2|Bacteria,1VATP@1239|Firmicutes,24Q9K@186801|Clostridia,3WPND@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized conserved protein (DUF2290)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2290
PKFBPKFJ_02361	1121115.AXVN01000077_gene2642	4.34e-22	87.4	2C9RV@1|root,32UDR@2|Bacteria,1VD3D@1239|Firmicutes,24NEV@186801|Clostridia,3Y1XJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02362	1121115.AXVN01000077_gene2644	1.13e-87	258.0	COG0853@1|root,COG0853@2|Bacteria,1V6NQ@1239|Firmicutes,24JVN@186801|Clostridia,3Y1QS@572511|Blautia	186801|Clostridia	H	Aspartate decarboxylase	panD	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
PKFBPKFJ_02363	1121115.AXVN01000077_gene2645	2.24e-200	555.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,248AN@186801|Clostridia,3Y13Y@572511|Blautia	186801|Clostridia	H	Pantoate-beta-alanine ligase	panC	-	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
PKFBPKFJ_02364	1121115.AXVN01000077_gene2646	2.44e-219	607.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,3Y1N1@572511|Blautia	186801|Clostridia	S	Sodium Bile acid symporter family	-	-	-	ko:K03453	-	-	-	-	ko00000	2.A.28	-	-	SBF
PKFBPKFJ_02365	457412.RSAG_00958	0.0	926.0	COG2508@1|root,COG2508@2|Bacteria,1TRRH@1239|Firmicutes,24C6R@186801|Clostridia,3WNTJ@541000|Ruminococcaceae	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
PKFBPKFJ_02366	457412.RSAG_00957	0.0	1880.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3WGSH@541000|Ruminococcaceae	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	ADC,Oxidored_FMN,Pyr_redox_2
PKFBPKFJ_02367	457412.RSAG_00956	4.6e-170	476.0	COG1028@1|root,COG1028@2|Bacteria,1TSND@1239|Firmicutes,24DU0@186801|Clostridia,3WS77@541000|Ruminococcaceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
PKFBPKFJ_02368	1121115.AXVN01000077_gene2653	4.53e-96	279.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia	186801|Clostridia	S	Belongs to the SOS response-associated peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
PKFBPKFJ_02370	1458462.JNLK01000001_gene2611	3.91e-60	206.0	COG0494@1|root,COG2110@1|root,COG5113@1|root,COG0494@2|Bacteria,COG2110@2|Bacteria,COG3236@2|Bacteria,1UY8T@1239|Firmicutes,2486K@186801|Clostridia,27NI1@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
PKFBPKFJ_02371	457412.RSAG_04690	1.86e-305	833.0	COG3385@1|root,COG3385@2|Bacteria,1UHBB@1239|Firmicutes,24ETX@186801|Clostridia	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PKFBPKFJ_02372	457412.RSAG_02028	0.0	1053.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3WGIS@541000|Ruminococcaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PKFBPKFJ_02373	457412.RSAG_02029	2.21e-156	439.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WH0X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_02374	457412.RSAG_02030	1.77e-237	654.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,3WJ5X@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_02375	1121115.AXVN01000152_gene3982	4.48e-161	451.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,3XZF5@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_02376	742765.HMPREF9457_02876	2.05e-276	756.0	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,249DS@186801|Clostridia,27WAV@189330|Dorea	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
PKFBPKFJ_02377	742765.HMPREF9457_02926	5.54e-50	158.0	2EMT3@1|root,33FFH@2|Bacteria,1VMD0@1239|Firmicutes,24V8U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02378	1121115.AXVN01000034_gene3883	3.64e-129	367.0	2DKVF@1|root,30GMW@2|Bacteria,1V8RI@1239|Firmicutes,250I2@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
PKFBPKFJ_02379	1121115.AXVN01000034_gene3882	3.49e-48	153.0	2EIQY@1|root,33CGC@2|Bacteria,1VN28@1239|Firmicutes,24WWB@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
PKFBPKFJ_02380	742765.HMPREF9457_02923	2.81e-33	114.0	299F4@1|root,2ZWHX@2|Bacteria,1W3YA@1239|Firmicutes,256JC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02381	411459.RUMOBE_02225	1.07e-86	254.0	COG5658@1|root,COG5658@2|Bacteria,1VB6E@1239|Firmicutes,24MSY@186801|Clostridia,3Y0NF@572511|Blautia	186801|Clostridia	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
PKFBPKFJ_02382	1235798.C817_05732	2.91e-38	136.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,24A19@186801|Clostridia,27WRE@189330|Dorea	186801|Clostridia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
PKFBPKFJ_02383	1235802.C823_04799	6.77e-167	472.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,24A19@186801|Clostridia,25WRD@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
PKFBPKFJ_02385	411461.DORFOR_03249	4.82e-09	55.8	28I1B@1|root,2Z860@2|Bacteria,1TT6W@1239|Firmicutes,24BUI@186801|Clostridia,27W5Q@189330|Dorea	186801|Clostridia	S	Protein of unknown function (DUF3801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
PKFBPKFJ_02386	428127.EUBDOL_00424	1.08e-38	130.0	2B1PF@1|root,2ZYHN@2|Bacteria,1V614@1239|Firmicutes,3VRD5@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02387	457412.RSAG_02035	3.13e-86	254.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3WIS1@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
PKFBPKFJ_02388	1121115.AXVN01000094_gene766	1.05e-101	294.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3XZVZ@572511|Blautia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
PKFBPKFJ_02389	1121115.AXVN01000094_gene765	1.57e-179	499.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3XYU9@572511|Blautia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
PKFBPKFJ_02390	1121115.AXVN01000094_gene764	2.89e-181	505.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,3XYPD@572511|Blautia	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
PKFBPKFJ_02391	1121115.AXVN01000094_gene763	1.09e-249	686.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3XZ7W@572511|Blautia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
PKFBPKFJ_02392	1121115.AXVN01000094_gene762	8.15e-204	563.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3XZE9@572511|Blautia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
PKFBPKFJ_02393	457412.RSAG_02041	2.08e-139	394.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,3WH1B@541000|Ruminococcaceae	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
PKFBPKFJ_02394	457412.RSAG_02042	0.0	1461.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3WH4M@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
PKFBPKFJ_02395	457412.RSAG_02043	6.6e-312	850.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3WGYG@541000|Ruminococcaceae	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
PKFBPKFJ_02396	1121115.AXVN01000094_gene758	2.01e-133	378.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,3XYT9@572511|Blautia	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
PKFBPKFJ_02397	1121115.AXVN01000094_gene757	1.26e-288	790.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3XYJC@572511|Blautia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
PKFBPKFJ_02398	457412.RSAG_02046	2.37e-124	355.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,3WJ0K@541000|Ruminococcaceae	186801|Clostridia	S	DJ-1 family	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
PKFBPKFJ_02399	1121115.AXVN01000094_gene755	0.0	975.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,2492H@186801|Clostridia,3XZGT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	abgB	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
PKFBPKFJ_02400	457412.RSAG_02051	1.92e-106	306.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia,3WJHM@541000|Ruminococcaceae	186801|Clostridia	S	CYTH	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
PKFBPKFJ_02401	1121115.AXVN01000189_gene1038	1.38e-182	508.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,3XZDC@572511|Blautia	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
PKFBPKFJ_02402	457412.RSAG_02053	1.17e-101	294.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3WJM2@541000|Ruminococcaceae	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
PKFBPKFJ_02403	457412.RSAG_02054	0.0	868.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_02404	457412.RSAG_02055	1.62e-229	630.0	COG2207@1|root,COG2207@2|Bacteria,1UYSR@1239|Firmicutes,248R9@186801|Clostridia,3WJXM@541000|Ruminococcaceae	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
PKFBPKFJ_02405	457412.RSAG_02056	3.58e-148	417.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,3WJ59@541000|Ruminococcaceae	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
PKFBPKFJ_02406	457412.RSAG_01896	1.58e-236	654.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
PKFBPKFJ_02407	457412.RSAG_02900	4.62e-57	180.0	2EUJQ@1|root,33N1P@2|Bacteria,1VMKN@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02408	1121115.AXVN01000049_gene1321	0.0	891.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pbuX	-	-	ko:K03458	-	-	-	-	ko00000	2.A.40	-	-	Xan_ur_permease
PKFBPKFJ_02409	457412.RSAG_02902	0.0	964.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,3WHMI@541000|Ruminococcaceae	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
PKFBPKFJ_02410	1121115.AXVN01000049_gene1318	6.25e-132	374.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,3XZUJ@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	trpG	-	4.1.3.27	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
PKFBPKFJ_02411	1121115.AXVN01000049_gene1317	3.14e-231	637.0	COG0547@1|root,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,3XZ38@572511|Blautia	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase,Glycos_trans_3N,Glycos_transf_3
PKFBPKFJ_02412	457412.RSAG_02905	1.04e-178	499.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,3WG9T@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the TrpC family	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
PKFBPKFJ_02413	1121115.AXVN01000049_gene1315	5.42e-144	406.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,3Y006@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
PKFBPKFJ_02414	1121115.AXVN01000049_gene1314	7e-287	783.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,3XYNP@572511|Blautia	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PKFBPKFJ_02415	1121115.AXVN01000049_gene1313	2.12e-179	500.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,3XYZ4@572511|Blautia	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
PKFBPKFJ_02416	457412.RSAG_02909	4.72e-199	550.0	COG0561@1|root,COG0561@2|Bacteria,1V2JE@1239|Firmicutes,25B80@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
PKFBPKFJ_02417	457412.RSAG_02911	5.23e-229	630.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,3WHA2@541000|Ruminococcaceae	186801|Clostridia	I	lipid kinase, YegS Rv2252 BmrU family	dagK	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
PKFBPKFJ_02418	457412.RSAG_02912	0.0	1404.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3WHCK@541000|Ruminococcaceae	186801|Clostridia	S	glutamine synthetase	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
PKFBPKFJ_02419	457412.RSAG_02913	1.26e-215	595.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,3WH7J@541000|Ruminococcaceae	186801|Clostridia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
PKFBPKFJ_02420	457412.RSAG_02914	0.0	1164.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,3WHZQ@541000|Ruminococcaceae	186801|Clostridia	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
PKFBPKFJ_02421	1121115.AXVN01000049_gene1307	0.0	1144.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,3XYVS@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	OPT
PKFBPKFJ_02422	1121115.AXVN01000049_gene1306	1.54e-84	249.0	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes,24QK3@186801|Clostridia,3Y0F4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
PKFBPKFJ_02423	457412.RSAG_02917	2.49e-198	550.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,25CBM@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
PKFBPKFJ_02424	1121115.AXVN01000049_gene1304	1.19e-255	701.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,3XYND@572511|Blautia	186801|Clostridia	QT	Psort location Cytoplasmic, score 8.87	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
PKFBPKFJ_02425	1121115.AXVN01000049_gene1303	1.28e-155	437.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,3XYQ6@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
PKFBPKFJ_02426	1121115.AXVN01000049_gene1302	2.82e-205	569.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,3XZN5@572511|Blautia	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
PKFBPKFJ_02427	457412.RSAG_02921	6.61e-277	758.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,3WGHH@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S41
PKFBPKFJ_02428	457412.RSAG_02922	3.61e-211	583.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,3WGR8@541000|Ruminococcaceae	186801|Clostridia	S	EDD domain protein, DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
PKFBPKFJ_02429	457412.RSAG_02923	0.0	1243.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,3WIIN@541000|Ruminococcaceae	186801|Clostridia	F	Belongs to the 5'-nucleotidase family	-	-	3.1.3.5,3.6.1.45	ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
PKFBPKFJ_02430	457412.RSAG_02924	1.75e-105	305.0	COG5113@1|root,COG3236@2|Bacteria,1UY8T@1239|Firmicutes,2486K@186801|Clostridia,3WGS9@541000|Ruminococcaceae	186801|Clostridia	O	Domain of unknown function (DUF1768)	-	-	-	ko:K09935	-	-	-	-	ko00000	-	-	-	DUF1768
PKFBPKFJ_02431	1121115.AXVN01000049_gene1298	1.33e-147	416.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia,3XYHQ@572511|Blautia	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
PKFBPKFJ_02432	457412.RSAG_03413	6.23e-62	190.0	COG1961@1|root,COG1961@2|Bacteria	2|Bacteria	L	recombinase activity	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_02433	457412.RSAG_03414	1.44e-227	627.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3WHUP@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin
PKFBPKFJ_02434	411461.DORFOR_00178	2.51e-72	217.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes	1239|Firmicutes	O	Belongs to the thioredoxin family	trxA	GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
PKFBPKFJ_02435	457412.RSAG_03416	9.82e-156	437.0	COG0664@1|root,COG0664@2|Bacteria,1V2MV@1239|Firmicutes,24B7K@186801|Clostridia,3WISN@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
PKFBPKFJ_02436	457412.RSAG_03417	0.0	1115.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,3WGIN@541000|Ruminococcaceae	186801|Clostridia	P	pyridine nucleotide-disulphide oxidoreductase dimerisation	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
PKFBPKFJ_02437	457412.RSAG_03418	5.52e-71	213.0	COG0607@1|root,COG0607@2|Bacteria,1U0PW@1239|Firmicutes,24RKU@186801|Clostridia,3WK9V@541000|Ruminococcaceae	186801|Clostridia	P	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
PKFBPKFJ_02438	411459.RUMOBE_03495	2.05e-66	201.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3Y0FX@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
PKFBPKFJ_02439	411459.RUMOBE_03494	8.25e-167	467.0	COG1028@1|root,COG1028@2|Bacteria,1TPIK@1239|Firmicutes,25073@186801|Clostridia,3XYII@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	baiA	-	1.1.1.100,1.1.1.159	ko:K00059,ko:K00076	ko00061,ko00121,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00121,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
PKFBPKFJ_02440	457412.RSAG_03422	2.63e-241	664.0	COG2199@1|root,COG2199@2|Bacteria,1V1A1@1239|Firmicutes,24CYN@186801|Clostridia,3WN05@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
PKFBPKFJ_02441	457412.RSAG_03423	2.4e-182	507.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,3WHH1@541000|Ruminococcaceae	186801|Clostridia	S	Peroxide stress protein YaaA	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
PKFBPKFJ_02442	457412.RSAG_04560	2.19e-84	248.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,3WIK4@541000|Ruminococcaceae	186801|Clostridia	O	Redoxin	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
PKFBPKFJ_02443	585394.RHOM_15045	2.78e-13	65.5	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia	186801|Clostridia	O	Antioxidant, AhpC TSA family	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
PKFBPKFJ_02444	457412.RSAG_03425	7.5e-23	89.4	2C9RV@1|root,32TYA@2|Bacteria,1VDD3@1239|Firmicutes,24T6T@186801|Clostridia,3WR16@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02445	457412.RSAG_03426	2.3e-96	280.0	2DE2W@1|root,2ZKAM@2|Bacteria,1V3EH@1239|Firmicutes,24GFD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02446	457412.RSAG_03427	2.87e-43	140.0	2D2HR@1|root,32TCU@2|Bacteria,1VA21@1239|Firmicutes,24MT0@186801|Clostridia	186801|Clostridia	S	Sporulation initiation factor Spo0A C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
PKFBPKFJ_02447	457412.RSAG_03428	2.38e-99	288.0	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia,3WKH1@541000|Ruminococcaceae	186801|Clostridia	P	Hemerythrin HHE cation binding domain	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
PKFBPKFJ_02448	457412.RSAG_03429	4.95e-37	124.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia,3WKG3@541000|Ruminococcaceae	186801|Clostridia	C	PFAM Rubredoxin-type Fe(Cys)4 protein	rd	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
PKFBPKFJ_02449	457412.RSAG_03430	2e-90	264.0	28PBY@1|root,2ZC4G@2|Bacteria,1V2G3@1239|Firmicutes,24HDX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02450	457412.RSAG_03431	1.6e-133	378.0	28KSD@1|root,2ZA9R@2|Bacteria,1UZZ4@1239|Firmicutes,249ZS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02451	457412.RSAG_03432	5.55e-54	168.0	2E5HW@1|root,33098@2|Bacteria,1VFFD@1239|Firmicutes,24QMD@186801|Clostridia,3WM6E@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02452	457412.RSAG_04562	4.07e-43	140.0	COG1974@1|root,COG1974@2|Bacteria,1VDZS@1239|Firmicutes,25E0Q@186801|Clostridia	186801|Clostridia	L	LexA DNA binding domain	-	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind
PKFBPKFJ_02453	457412.RSAG_03433	1.45e-150	423.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
PKFBPKFJ_02454	457412.RSAG_03434	5e-124	353.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3WGBH@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
PKFBPKFJ_02455	457412.RSAG_03435	1.58e-198	550.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia,3WI2P@541000|Ruminococcaceae	186801|Clostridia	G	Delta-lactam-biosynthetic de-N-acetylase	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
PKFBPKFJ_02456	457412.RSAG_03436	2.07e-217	602.0	COG0834@1|root,COG0834@2|Bacteria,1TT11@1239|Firmicutes,249IK@186801|Clostridia,3WMX0@541000|Ruminococcaceae	186801|Clostridia	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
PKFBPKFJ_02457	1121115.AXVN01000161_gene1323	1.95e-171	479.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia	186801|Clostridia	E	abc transporter atp-binding protein	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
PKFBPKFJ_02458	1121115.AXVN01000161_gene1324	1.05e-153	432.0	COG0765@1|root,COG0765@2|Bacteria,1TR7R@1239|Firmicutes,24823@186801|Clostridia	186801|Clostridia	P	acid ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
PKFBPKFJ_02459	1121115.AXVN01000161_gene1325	3.25e-145	410.0	COG0765@1|root,COG0765@2|Bacteria,1TRU3@1239|Firmicutes,249IY@186801|Clostridia	186801|Clostridia	P	ABC transporter, permease protein	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
PKFBPKFJ_02460	1121115.AXVN01000161_gene1326	3.47e-154	432.0	COG2755@1|root,COG2755@2|Bacteria,1V49F@1239|Firmicutes,24D1K@186801|Clostridia,3Y0I8@572511|Blautia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
PKFBPKFJ_02461	457412.RSAG_03441	1.13e-172	483.0	COG2207@1|root,COG2207@2|Bacteria,1U23Q@1239|Firmicutes,25BMJ@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
PKFBPKFJ_02462	1121115.AXVN01000186_gene2049	0.0	1459.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XYUA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	bglB	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PKFBPKFJ_02463	1121115.AXVN01000153_gene3989	1.43e-296	808.0	COG0161@1|root,COG0161@2|Bacteria,1TP9N@1239|Firmicutes,25E7B@186801|Clostridia,3Y0YH@572511|Blautia	186801|Clostridia	H	Aminotransferase class-III	bioA	-	2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77	ko:K00833,ko:K03851,ko:K12256,ko:K15372	ko00330,ko00410,ko00430,ko00780,ko01100,map00330,map00410,map00430,map00780,map01100	M00123,M00573,M00577	R00908,R01684,R03231,R05652,R08714	RC00006,RC00008,RC00062,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PKFBPKFJ_02464	1121115.AXVN01000153_gene3988	2.81e-166	464.0	COG0132@1|root,COG0132@2|Bacteria,1UYA3@1239|Firmicutes,24F15@186801|Clostridia,3Y0X3@572511|Blautia	186801|Clostridia	H	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring	bioD	-	6.3.3.3	ko:K01935	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03182	RC00868	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26
PKFBPKFJ_02465	457412.RSAG_03445	1.47e-242	665.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,248J4@186801|Clostridia,3WGM8@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
PKFBPKFJ_02466	457412.RSAG_03446	1.92e-133	379.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HU5@186801|Clostridia,3WK6N@541000|Ruminococcaceae	186801|Clostridia	S	BioY family	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
PKFBPKFJ_02467	1121115.AXVN01000153_gene3985	1.94e-100	291.0	COG3610@1|root,COG3610@2|Bacteria,1UVFM@1239|Firmicutes,257UX@186801|Clostridia,3Y1J9@572511|Blautia	186801|Clostridia	S	Putative threonine/serine exporter	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
PKFBPKFJ_02468	1121115.AXVN01000153_gene3984	3.4e-178	496.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,3Y0H6@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE,ThrE_2
PKFBPKFJ_02471	1121115.AXVN01000090_gene2570	0.0	873.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,3XZM9@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
PKFBPKFJ_02472	1121115.AXVN01000090_gene2571	1.98e-136	386.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,3Y00P@572511|Blautia	186801|Clostridia	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
PKFBPKFJ_02473	1121115.AXVN01000090_gene2572	3.73e-303	826.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,3XYRP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
PKFBPKFJ_02474	1121115.AXVN01000012_gene3090	1.05e-179	501.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,3XZG0@572511|Blautia	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
PKFBPKFJ_02475	1121115.AXVN01000012_gene3091	7.54e-40	132.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,25HV0@186801|Clostridia,3Y0TI@572511|Blautia	186801|Clostridia	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
PKFBPKFJ_02477	1121115.AXVN01000012_gene3092	0.0	1199.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,3XZ6F@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
PKFBPKFJ_02478	457412.RSAG_02734	2.8e-229	631.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,249GM@186801|Clostridia,3WGAM@541000|Ruminococcaceae	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
PKFBPKFJ_02479	457412.RSAG_02735	1.51e-180	501.0	COG0406@1|root,COG0406@2|Bacteria,1U7UE@1239|Firmicutes,24F5B@186801|Clostridia,3WI6A@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
PKFBPKFJ_02480	1121115.AXVN01000012_gene3095	3.75e-210	580.0	COG1940@1|root,COG1940@2|Bacteria,1TP04@1239|Firmicutes,248SD@186801|Clostridia,3XZGU@572511|Blautia	186801|Clostridia	GK	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ROK
PKFBPKFJ_02481	1121115.AXVN01000012_gene3097	2.03e-220	607.0	COG0329@1|root,COG0329@2|Bacteria,1TQRK@1239|Firmicutes,247ZW@186801|Clostridia,3XZN3@572511|Blautia	186801|Clostridia	EM	Belongs to the DapA family	nanA	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
PKFBPKFJ_02482	1121115.AXVN01000012_gene3098	5.48e-235	646.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,3XYQ8@572511|Blautia	186801|Clostridia	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PKFBPKFJ_02483	457412.RSAG_02739	0.0	914.0	COG1653@1|root,COG1653@2|Bacteria,1TSD1@1239|Firmicutes,24BXR@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
PKFBPKFJ_02484	457412.RSAG_02740	1.23e-191	532.0	COG0395@1|root,COG0395@2|Bacteria,1V2AA@1239|Firmicutes,24G54@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_02485	457412.RSAG_02741	9.95e-211	582.0	COG1175@1|root,COG1175@2|Bacteria,1V0QC@1239|Firmicutes,24DRD@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_02486	1121115.AXVN01000012_gene3102	1.19e-198	551.0	COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,24BR4@186801|Clostridia,3Y2BX@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
PKFBPKFJ_02487	1121115.AXVN01000012_gene3103	3.53e-163	457.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,3XZHW@572511|Blautia	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
PKFBPKFJ_02488	1121115.AXVN01000012_gene3104	7.88e-268	733.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,3XYYH@572511|Blautia	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
PKFBPKFJ_02489	1121115.AXVN01000012_gene3105	6.35e-175	488.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,3XYUH@572511|Blautia	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
PKFBPKFJ_02490	1121115.AXVN01000012_gene3106	5.9e-194	538.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,3XZRH@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
PKFBPKFJ_02491	457412.RSAG_02747	0.0	1031.0	COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,2497J@186801|Clostridia,3WHPB@541000|Ruminococcaceae	186801|Clostridia	G	Alpha-L-arabinofuranosidase domain protein	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
PKFBPKFJ_02492	478749.BRYFOR_05012	4.93e-104	306.0	COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,249MU@186801|Clostridia	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_02493	457412.RSAG_02749	3.28e-232	637.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,3WN40@541000|Ruminococcaceae	186801|Clostridia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24
PKFBPKFJ_02494	1121115.AXVN01000012_gene3115	0.0	1291.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y14N@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
PKFBPKFJ_02495	1121115.AXVN01000012_gene3116	2.87e-61	187.0	2DPI5@1|root,3326E@2|Bacteria,1VIQZ@1239|Firmicutes,24QSZ@186801|Clostridia,3Y27B@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02496	457412.RSAG_02752	2.71e-66	201.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia	186801|Clostridia	G	Alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
PKFBPKFJ_02497	457412.RSAG_01470	1.61e-124	360.0	COG1396@1|root,COG1396@2|Bacteria,1V7ID@1239|Firmicutes,24DIG@186801|Clostridia	186801|Clostridia	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF2007,HTH_3
PKFBPKFJ_02498	397287.C807_01799	1.26e-08	50.8	2BEY0@1|root,328PP@2|Bacteria,1UUMP@1239|Firmicutes,25766@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02499	1121115.AXVN01000065_gene684	4.3e-151	425.0	COG3859@1|root,COG3859@2|Bacteria,1V1WX@1239|Firmicutes,24E4Z@186801|Clostridia,3XZ3K@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yuaJ	-	-	ko:K16789	-	-	-	-	ko00000,ko02000	2.A.88.3	-	-	Thia_YuaJ
PKFBPKFJ_02500	457412.RSAG_01468	5.08e-112	321.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,3WJKY@541000|Ruminococcaceae	186801|Clostridia	F	Psort location Cytoplasmic, score 8.96	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
PKFBPKFJ_02501	1121115.AXVN01000065_gene686	2.28e-77	231.0	COG0239@1|root,COG0239@2|Bacteria,1TTU1@1239|Firmicutes,259CY@186801|Clostridia,3Y0J4@572511|Blautia	186801|Clostridia	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	-	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
PKFBPKFJ_02502	457412.RSAG_01466	9.89e-239	655.0	28M41@1|root,2ZAI3@2|Bacteria,1UZMW@1239|Firmicutes,24ANU@186801|Clostridia,3WHAM@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220
PKFBPKFJ_02503	457412.RSAG_01465	4.34e-209	579.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,3WGDH@541000|Ruminococcaceae	186801|Clostridia	P	K -dependent Na Ca exchanger family protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
PKFBPKFJ_02504	457412.RSAG_01464	3.07e-148	417.0	2BC4V@1|root,325PN@2|Bacteria,1URQ2@1239|Firmicutes,24ZYA@186801|Clostridia,3WQB6@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
PKFBPKFJ_02505	457412.RSAG_01463	0.0	1041.0	28I9Q@1|root,2Z8CD@2|Bacteria,1TQ4H@1239|Firmicutes,24B8Q@186801|Clostridia,3WREU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02506	457412.RSAG_01462	6.5e-163	457.0	28MFF@1|root,2ZASX@2|Bacteria,1TQD0@1239|Firmicutes,24996@186801|Clostridia,3WMED@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02507	457412.RSAG_01461	0.0	2655.0	COG1196@1|root,COG1196@2|Bacteria,1TR05@1239|Firmicutes,24BXV@186801|Clostridia,3WJQR@541000|Ruminococcaceae	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02509	1121115.AXVN01000069_gene2315	3.2e-116	333.0	COG1595@1|root,COG1595@2|Bacteria,1TPJJ@1239|Firmicutes,24JUX@186801|Clostridia,3Y0D0@572511|Blautia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_02510	1121115.AXVN01000069_gene2316	6.85e-146	412.0	29XH4@1|root,30J7T@2|Bacteria,1UVPT@1239|Firmicutes,2503Y@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02511	457412.RSAG_01457	8.34e-194	538.0	COG1284@1|root,COG1284@2|Bacteria,1TYTP@1239|Firmicutes,25CBP@186801|Clostridia,3WSC5@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
PKFBPKFJ_02512	1121115.AXVN01000069_gene2318	1.83e-297	813.0	COG1757@1|root,COG1757@2|Bacteria,1TQPI@1239|Firmicutes,2495U@186801|Clostridia,3XZ6V@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	mleN_2	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
PKFBPKFJ_02513	1121115.AXVN01000069_gene2319	1.49e-138	393.0	COG0789@1|root,COG0789@2|Bacteria,1V53F@1239|Firmicutes,24IQ8@186801|Clostridia,3Y2B8@572511|Blautia	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
PKFBPKFJ_02514	1121115.AXVN01000069_gene2320	1.61e-64	197.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,3Y0P1@572511|Blautia	186801|Clostridia	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
PKFBPKFJ_02515	457412.RSAG_01453	2.48e-91	268.0	2DM5I@1|root,31T37@2|Bacteria,1V6J6@1239|Firmicutes,24K9S@186801|Clostridia,3WJPG@541000|Ruminococcaceae	186801|Clostridia	S	SseB protein N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SseB
PKFBPKFJ_02516	457412.RSAG_01452	1.83e-313	855.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGER@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_02517	1121115.AXVN01000120_gene2843	4.89e-105	303.0	COG1633@1|root,COG1633@2|Bacteria,1V72Y@1239|Firmicutes,24JY4@186801|Clostridia,3Y12U@572511|Blautia	186801|Clostridia	S	Coat F domain	-	-	-	-	-	-	-	-	-	-	-	-	Coat_F,Rubrerythrin
PKFBPKFJ_02518	1121115.AXVN01000120_gene2840	7.24e-200	559.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3XZ8Q@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
PKFBPKFJ_02519	1121115.AXVN01000120_gene2839	0.0	1146.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3Y12M@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 32	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
PKFBPKFJ_02520	1121115.AXVN01000120_gene2838	9.58e-317	862.0	COG2182@1|root,COG2182@2|Bacteria,1V2WM@1239|Firmicutes,24CQZ@186801|Clostridia,3Y28I@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10120	-	M00197,M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1,3.A.1.1.20	-	-	SBP_bac_8
PKFBPKFJ_02521	1121115.AXVN01000120_gene2837	5.73e-208	575.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,249MK@186801|Clostridia,3XZBN@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	msmF	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PKFBPKFJ_02522	1121115.AXVN01000120_gene2836	8.82e-185	515.0	COG0395@1|root,COG0395@2|Bacteria,1UCH2@1239|Firmicutes,24AS5@186801|Clostridia,3XZF4@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_02523	1121115.AXVN01000120_gene2835	3.85e-65	199.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_02525	1121115.AXVN01000104_gene843	0.0	953.0	COG0437@1|root,COG4624@1|root,COG0437@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,3XYSR@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
PKFBPKFJ_02527	457412.RSAG_01508	1.76e-156	443.0	COG2755@1|root,COG2755@2|Bacteria,1VDI9@1239|Firmicutes,24MZY@186801|Clostridia	186801|Clostridia	E	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL,SH3_3
PKFBPKFJ_02529	1121115.AXVN01000104_gene845	7.3e-59	181.0	2C9HP@1|root,33Z9H@2|Bacteria,1W1CU@1239|Firmicutes,25441@186801|Clostridia,3Y0HT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02530	742735.HMPREF9467_05210	8.08e-195	554.0	COG3385@1|root,COG3385@2|Bacteria,1UTR4@1239|Firmicutes,24CFF@186801|Clostridia,221YR@1506553|Lachnoclostridium	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PKFBPKFJ_02531	1121115.AXVN01000104_gene846	0.0	1070.0	COG2895@1|root,COG2895@2|Bacteria,1UI8R@1239|Firmicutes,249BX@186801|Clostridia,3Y116@572511|Blautia	186801|Clostridia	H	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysN	-	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
PKFBPKFJ_02532	457412.RSAG_01511	1.27e-270	740.0	COG0175@1|root,COG0175@2|Bacteria,1U1VN@1239|Firmicutes,248Y9@186801|Clostridia,3WJJK@541000|Ruminococcaceae	186801|Clostridia	EH	PFAM Phosphoadenosine phosphosulfate reductase	cysD	-	1.8.4.10,1.8.4.8,2.7.7.4	ko:K00390,ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R02021,R04929	RC00007,RC02809,RC02862,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
PKFBPKFJ_02533	1121115.AXVN01000104_gene848	1.26e-75	225.0	COG1146@1|root,COG1146@2|Bacteria,1VADW@1239|Firmicutes,24MQA@186801|Clostridia,3Y1XY@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.99.2	ko:K00395	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_9
PKFBPKFJ_02534	1121115.AXVN01000104_gene849	0.0	1127.0	COG1053@1|root,COG1053@2|Bacteria,1TRE8@1239|Firmicutes,247TH@186801|Clostridia,3Y0UM@572511|Blautia	186801|Clostridia	C	FAD binding domain	aprA	-	1.8.99.2	ko:K00394	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00596	R00860,R04927,R08553	RC00007,RC01239,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
PKFBPKFJ_02535	457412.RSAG_01514	3.1e-246	677.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3WSP6@541000|Ruminococcaceae	186801|Clostridia	E	ATPases associated with a variety of cellular activities	cysA	-	3.6.3.25	ko:K02045,ko:K02052	ko00920,ko02010,ko02024,map00920,map02010,map02024	M00185,M00193	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.6.1,3.A.1.6.3	-	-	ABC_tran,TOBE_2
PKFBPKFJ_02536	457412.RSAG_01515	8.56e-182	507.0	COG4208@1|root,COG4208@2|Bacteria,1TS3N@1239|Firmicutes,24C3X@186801|Clostridia,3WHKV@541000|Ruminococcaceae	186801|Clostridia	P	sulfate ABC transporter	cysW	-	-	ko:K02047	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	BPD_transp_1
PKFBPKFJ_02537	457412.RSAG_01516	2.19e-186	519.0	COG0555@1|root,COG0555@2|Bacteria,1TQHR@1239|Firmicutes,24ACM@186801|Clostridia,3WIAX@541000|Ruminococcaceae	186801|Clostridia	P	Sulfate ABC transporter, permease protein CysT	cysT	-	-	ko:K02046,ko:K15496	ko00920,ko02010,map00920,map02010	M00185,M00423	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3,3.A.1.6.5	-	-	BPD_transp_1
PKFBPKFJ_02538	457412.RSAG_01517	1.79e-244	671.0	COG1613@1|root,COG1613@2|Bacteria,1TS25@1239|Firmicutes,24B9S@186801|Clostridia,3WGXR@541000|Ruminococcaceae	186801|Clostridia	P	Extracellular solute-binding protein	sbp	-	-	ko:K02048	ko00920,ko02010,map00920,map02010	M00185	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.6.1,3.A.1.6.3	-	-	SBP_bac_11
PKFBPKFJ_02539	1121115.AXVN01000104_gene854	2.37e-110	317.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3Y07W@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
PKFBPKFJ_02540	1121115.AXVN01000123_gene2860	3.93e-160	449.0	COG4816@1|root,COG4816@2|Bacteria,1TTAA@1239|Firmicutes,2498G@186801|Clostridia,3XZIA@572511|Blautia	186801|Clostridia	E	BMC domain	-	-	-	-	-	-	-	-	-	-	-	-	BMC
PKFBPKFJ_02541	457412.RSAG_01521	9.07e-211	584.0	COG1172@1|root,COG1172@2|Bacteria,1U0FI@1239|Firmicutes,24B5S@186801|Clostridia,3WPSA@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
PKFBPKFJ_02542	457412.RSAG_01522	0.0	972.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3WGJM@541000|Ruminococcaceae	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
PKFBPKFJ_02543	457412.RSAG_01523	1.02e-208	578.0	COG1172@1|root,COG1172@2|Bacteria,1UVPQ@1239|Firmicutes,25MGQ@186801|Clostridia,3WPXD@541000|Ruminococcaceae	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
PKFBPKFJ_02544	457412.RSAG_01524	1.31e-268	736.0	COG1609@1|root,COG1609@2|Bacteria	2|Bacteria	K	purine nucleotide biosynthetic process	-	-	-	ko:K03406,ko:K10439	ko02010,ko02020,ko02030,map02010,map02020,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	GntR,Peripla_BP_3,Peripla_BP_4
PKFBPKFJ_02545	457412.RSAG_01525	0.0	1012.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSFI@1239|Firmicutes,249B8@186801|Clostridia,3WH94@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
PKFBPKFJ_02546	457412.RSAG_01526	0.0	1134.0	COG2972@1|root,COG2972@2|Bacteria,1UQDY@1239|Firmicutes,249HG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
PKFBPKFJ_02547	1121115.AXVN01000123_gene2863	1.83e-298	814.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3XZFW@572511|Blautia	186801|Clostridia	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
PKFBPKFJ_02548	457412.RSAG_00903	6.8e-148	417.0	COG2452@1|root,COG2452@2|Bacteria,1TQNJ@1239|Firmicutes,24B79@186801|Clostridia	186801|Clostridia	L	protein MJ0014 - Methanococcus jannaschii gi 1590824 gb AAB97992.1 (U67460) conserved	-	-	-	ko:K07450	-	-	-	-	ko00000	-	-	-	MerR,MerR_1,Resolvase
PKFBPKFJ_02549	457412.RSAG_00902	1.96e-130	378.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
PKFBPKFJ_02550	457412.RSAG_03500	1.16e-256	705.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
PKFBPKFJ_02551	1121115.AXVN01000130_gene189	3.22e-90	264.0	COG5361@1|root,COG5361@2|Bacteria,1U2H3@1239|Firmicutes,24F4F@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
PKFBPKFJ_02552	1121115.AXVN01000130_gene188	6.38e-194	538.0	COG2820@1|root,COG2820@2|Bacteria,1TSEU@1239|Firmicutes,25E2U@186801|Clostridia,3XZ3Q@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
PKFBPKFJ_02553	457412.RSAG_03479	1.94e-104	301.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,3WK22@541000|Ruminococcaceae	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
PKFBPKFJ_02554	1121115.AXVN01000130_gene186	6.35e-300	816.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,3XYUY@572511|Blautia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08920	Metalloenzyme
PKFBPKFJ_02555	1121115.AXVN01000130_gene185	7.39e-113	323.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3XZW2@572511|Blautia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
PKFBPKFJ_02556	457412.RSAG_03476	1.92e-302	824.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3WG9G@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
PKFBPKFJ_02557	1121115.AXVN01000130_gene183	3.24e-113	325.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FR6@186801|Clostridia,3Y1GQ@572511|Blautia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
PKFBPKFJ_02558	1121115.AXVN01000130_gene182	1.03e-301	822.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3Y1H7@572511|Blautia	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	hacA	-	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
PKFBPKFJ_02559	457412.RSAG_03473	0.0	1030.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3WHR7@541000|Ruminococcaceae	186801|Clostridia	E	Aminotransferase class I and II	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,HTH_3
PKFBPKFJ_02560	1121115.AXVN01000088_gene4037	4.8e-139	392.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3XZX6@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
PKFBPKFJ_02561	457412.RSAG_03471	0.0	1594.0	COG4886@1|root,COG4886@2|Bacteria,1UKIE@1239|Firmicutes,25FXV@186801|Clostridia	186801|Clostridia	S	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
PKFBPKFJ_02562	1121115.AXVN01000088_gene4039	2.8e-295	813.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3XYWG@572511|Blautia	186801|Clostridia	O	COG COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
PKFBPKFJ_02563	1121115.AXVN01000088_gene4040	4.76e-78	233.0	COG2198@1|root,COG2198@2|Bacteria,1TUB6@1239|Firmicutes,257TB@186801|Clostridia,3Y0UT@572511|Blautia	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
PKFBPKFJ_02564	1121115.AXVN01000088_gene4041	6.65e-153	429.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24DES@186801|Clostridia,3Y0DJ@572511|Blautia	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
PKFBPKFJ_02565	457412.RSAG_03467	2.33e-190	533.0	COG5263@1|root,COG5263@2|Bacteria,1VQWH@1239|Firmicutes,24ZPP@186801|Clostridia	186801|Clostridia	S	Putative cell wall binding repeat	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
PKFBPKFJ_02566	457412.RSAG_03466	3.26e-151	426.0	2EYGG@1|root,33RQD@2|Bacteria,1VRY6@1239|Firmicutes,24XIB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02567	457412.RSAG_03465	3.39e-182	507.0	COG2720@1|root,COG2720@2|Bacteria,1V5AV@1239|Firmicutes,24XQ2@186801|Clostridia,3WJKU@541000|Ruminococcaceae	186801|Clostridia	V	Vancomycin resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3,Transglut_core
PKFBPKFJ_02568	1121115.AXVN01000088_gene4046	2.17e-151	434.0	2ECV2@1|root,336SH@2|Bacteria,1VFTD@1239|Firmicutes,24WJ4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02569	457412.RSAG_03463	0.0	1011.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3WH71@541000|Ruminococcaceae	186801|Clostridia	M	MBOAT, membrane-bound O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	MBOAT
PKFBPKFJ_02570	457412.RSAG_03462	2.83e-238	654.0	COG2755@1|root,COG2755@2|Bacteria,1VC24@1239|Firmicutes,258FA@186801|Clostridia,3WMJV@541000|Ruminococcaceae	186801|Clostridia	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02571	1121115.AXVN01000088_gene4049	0.0	1018.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia	186801|Clostridia	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,PP-binding
PKFBPKFJ_02572	457412.RSAG_03460	2.12e-295	805.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,3WH2M@541000|Ruminococcaceae	186801|Clostridia	E	Pyridoxal-dependent decarboxylase, pyridoxal binding domain	-	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
PKFBPKFJ_02573	1121115.AXVN01000088_gene4051	9.66e-46	147.0	COG0236@1|root,COG0236@2|Bacteria,1VEX6@1239|Firmicutes,24QWP@186801|Clostridia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
PKFBPKFJ_02574	457412.RSAG_02313	0.0	1144.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia	186801|Clostridia	O	Belongs to the peptidase S8 family	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
PKFBPKFJ_02575	457412.RSAG_02315	1.89e-134	382.0	28PIW@1|root,2ZC8Q@2|Bacteria,1V1ZT@1239|Firmicutes,24FWM@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
PKFBPKFJ_02576	457412.RSAG_02316	2e-206	570.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3WGWZ@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_02577	397288.C806_01618	6.48e-78	232.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,27MSR@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, gntR family	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
PKFBPKFJ_02578	457412.RSAG_02319	1.71e-49	157.0	2CIKK@1|root,32TFN@2|Bacteria,1VAVR@1239|Firmicutes,24PS4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02579	1121115.AXVN01000011_gene3411	0.0	1094.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYKU@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_02580	457412.RSAG_02321	0.0	1091.0	COG1961@1|root,COG1961@2|Bacteria,1TQ8Y@1239|Firmicutes,247WD@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_02581	1121115.AXVN01000011_gene3438	0.0	1008.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia,3XZC2@572511|Blautia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_02582	457412.RSAG_02323	0.0	881.0	COG1106@1|root,COG1106@2|Bacteria,1TSBY@1239|Firmicutes,249DS@186801|Clostridia,3WJY3@541000|Ruminococcaceae	186801|Clostridia	S	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K06926	-	-	-	-	ko00000	-	-	-	AAA_21
PKFBPKFJ_02583	457412.RSAG_02324	7.78e-158	442.0	28HPF@1|root,2Z98R@2|Bacteria,1UZQH@1239|Firmicutes,24DVV@186801|Clostridia,3WRZF@541000|Ruminococcaceae	186801|Clostridia	S	RloB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	RloB
PKFBPKFJ_02584	457412.RSAG_02325	1.57e-172	480.0	COG1489@1|root,COG1489@2|Bacteria,1VTYF@1239|Firmicutes,25E56@186801|Clostridia,3WS62@541000|Ruminococcaceae	186801|Clostridia	S	Belongs to the SfsA family	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
PKFBPKFJ_02585	457412.RSAG_02327	8.63e-188	523.0	2F1N0@1|root,33UNB@2|Bacteria,1VUUW@1239|Firmicutes,250GG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02586	457412.RSAG_02328	5.32e-147	426.0	2C1YG@1|root,30J7S@2|Bacteria,1TVA7@1239|Firmicutes,25A6I@186801|Clostridia,3WR8T@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02587	457412.RSAG_02329	0.0	1086.0	2DBJI@1|root,2Z9M2@2|Bacteria,1V4CA@1239|Firmicutes,24IGG@186801|Clostridia,3WIQJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_7TM
PKFBPKFJ_02588	457412.RSAG_02330	0.0	871.0	COG4585@1|root,COG4585@2|Bacteria,1V4GJ@1239|Firmicutes,24M3N@186801|Clostridia,3WJCM@541000|Ruminococcaceae	186801|Clostridia	T	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02589	457412.RSAG_02331	2.52e-148	417.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,24E7M@186801|Clostridia,3WJQ7@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K07694	ko02020,map02020	M00480	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
PKFBPKFJ_02590	457412.RSAG_02332	7.63e-218	600.0	2BB5X@1|root,324NG@2|Bacteria,1V7KI@1239|Firmicutes,24MCT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02592	457412.RSAG_02335	0.0	1321.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3WGZ1@541000|Ruminococcaceae	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4_10,Fer4_7,Fer4_8,MTHFR_C,RnfC_N,SLBB
PKFBPKFJ_02593	1121115.AXVN01000011_gene3446	3.47e-154	432.0	COG4656@1|root,COG4656@2|Bacteria,1TS9H@1239|Firmicutes,24DQ7@186801|Clostridia,3XYYU@572511|Blautia	186801|Clostridia	C	Methylene-tetrahydrofolate reductase C terminal	metV	-	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS18525	MTHFR_C
PKFBPKFJ_02594	1121115.AXVN01000011_gene3447	7.26e-208	575.0	COG0685@1|root,COG0685@2|Bacteria,1UHX4@1239|Firmicutes,25E62@186801|Clostridia,3XYTN@572511|Blautia	186801|Clostridia	C	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
PKFBPKFJ_02595	1121115.AXVN01000036_gene2434	3.53e-200	555.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,3Y023@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PKFBPKFJ_02596	1121115.AXVN01000036_gene2433	2.44e-211	584.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia,3Y17Y@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PKFBPKFJ_02597	1121115.AXVN01000036_gene2432	0.0	892.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3Y0CH@572511|Blautia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
PKFBPKFJ_02598	1121115.AXVN01000036_gene2431	1.47e-241	664.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24A4M@186801|Clostridia,3Y0YZ@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529,ko:K03604	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
PKFBPKFJ_02599	1121115.AXVN01000036_gene2430	0.0	1705.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3Y0G0@572511|Blautia	186801|Clostridia	G	Putative carbohydrate binding domain	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
PKFBPKFJ_02600	1121115.AXVN01000036_gene2429	0.0	1300.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3XYSJ@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
PKFBPKFJ_02601	1121115.AXVN01000036_gene2428	1.7e-263	720.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3XYHE@572511|Blautia	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
PKFBPKFJ_02602	457412.RSAG_02340	3.75e-109	315.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,3WJEQ@541000|Ruminococcaceae	186801|Clostridia	S	small multi-drug export protein	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
PKFBPKFJ_02603	457412.RSAG_02341	0.0	895.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,3WGZQ@541000|Ruminococcaceae	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
PKFBPKFJ_02604	1121115.AXVN01000036_gene2417	1.02e-46	149.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3Y0G4@572511|Blautia	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
PKFBPKFJ_02605	1121115.AXVN01000036_gene2416	1.28e-207	577.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,3XYUQ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
PKFBPKFJ_02606	1121115.AXVN01000036_gene2415	9.79e-232	637.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,3XZ9I@572511|Blautia	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
PKFBPKFJ_02607	1121115.AXVN01000036_gene2414	3.11e-249	685.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3XYXD@572511|Blautia	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
PKFBPKFJ_02608	1121115.AXVN01000036_gene2413	8.93e-220	606.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3XYIA@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
PKFBPKFJ_02609	1121115.AXVN01000036_gene2412	0.0	886.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3XYSV@572511|Blautia	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
PKFBPKFJ_02610	1121115.AXVN01000036_gene2411	5.16e-248	681.0	COG0457@1|root,COG0457@2|Bacteria,1V4J9@1239|Firmicutes,24VUT@186801|Clostridia,3XYS1@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
PKFBPKFJ_02611	1121115.AXVN01000036_gene2410	5.11e-284	777.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,3XZ8M@572511|Blautia	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
PKFBPKFJ_02612	457412.RSAG_02349	0.0	1608.0	COG0695@1|root,COG1328@1|root,COG0695@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3WGUQ@541000|Ruminococcaceae	186801|Clostridia	F	TIGRFAM anaerobic ribonucleoside-triphosphate reductase	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,Glutaredoxin,NRDD
PKFBPKFJ_02613	1121115.AXVN01000036_gene2408	8.01e-96	280.0	COG4747@1|root,COG4747@2|Bacteria,1V8ZY@1239|Firmicutes,24NAM@186801|Clostridia,3Y0M9@572511|Blautia	186801|Clostridia	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02614	1121115.AXVN01000036_gene2407	4.8e-99	287.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3Y0EE@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
PKFBPKFJ_02615	457412.RSAG_02352	2.46e-219	605.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3WG9Z@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the cysteine synthase cystathionine beta- synthase family	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
PKFBPKFJ_02616	1121115.AXVN01000036_gene2405	6.47e-268	732.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,3XZBE@572511|Blautia	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	trmU	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
PKFBPKFJ_02617	1121115.AXVN01000036_gene2404	6.37e-314	855.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
PKFBPKFJ_02618	457412.RSAG_02355	9.32e-191	531.0	2C6CR@1|root,2Z7X4@2|Bacteria,1UY2Y@1239|Firmicutes,24EJP@186801|Clostridia,3WIK3@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_2
PKFBPKFJ_02620	1121115.AXVN01000016_gene3696	6.37e-102	294.0	COG0735@1|root,COG0735@2|Bacteria,1V970@1239|Firmicutes,25MW0@186801|Clostridia,3Y26V@572511|Blautia	186801|Clostridia	P	Ferric uptake regulator family	-	-	-	-	-	-	-	-	-	-	-	-	FUR
PKFBPKFJ_02621	1121115.AXVN01000016_gene3695	3.84e-215	597.0	COG2755@1|root,COG2755@2|Bacteria,1VR4N@1239|Firmicutes,24YVH@186801|Clostridia,3Y0AM@572511|Blautia	186801|Clostridia	E	Listeria-Bacteroides repeat domain (List_Bact_rpt)	-	-	-	-	-	-	-	-	-	-	-	-	Flg_new
PKFBPKFJ_02622	1121115.AXVN01000016_gene3694	2.52e-153	432.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,3XZSK@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.99	ygaZ	-	-	-	-	-	-	-	-	-	-	-	AzlC
PKFBPKFJ_02623	1121115.AXVN01000016_gene3693	1.17e-58	182.0	COG4392@1|root,COG4392@2|Bacteria,1VAKN@1239|Firmicutes,24N0I@186801|Clostridia,3Y0E3@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
PKFBPKFJ_02624	1121115.AXVN01000016_gene3692	1.94e-204	565.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3XZFN@572511|Blautia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
PKFBPKFJ_02625	1121115.AXVN01000016_gene3691	1.16e-179	501.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3XYTF@572511|Blautia	186801|Clostridia	ET	COG COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	artP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
PKFBPKFJ_02626	457412.RSAG_04630	2.46e-157	442.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,3WHWM@541000|Ruminococcaceae	186801|Clostridia	P	acid ABC transporter	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
PKFBPKFJ_02627	457412.RSAG_02362	1.33e-171	479.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3WGJA@541000|Ruminococcaceae	186801|Clostridia	E	ABC-type polar amino acid transport system ATPase component	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
PKFBPKFJ_02628	457412.RSAG_02363	4.24e-219	605.0	COG0385@1|root,COG0385@2|Bacteria,1TP85@1239|Firmicutes,24A3I@186801|Clostridia,3WND9@541000|Ruminococcaceae	186801|Clostridia	S	Sodium Bile acid symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SBF
PKFBPKFJ_02629	457412.RSAG_02364	2.59e-97	283.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia,3WKBA@541000|Ruminococcaceae	186801|Clostridia	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
PKFBPKFJ_02630	1121115.AXVN01000016_gene3686	1.94e-245	673.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia,3XYZ8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
PKFBPKFJ_02631	457412.RSAG_02366	1.94e-194	544.0	2EYFJ@1|root,33RPG@2|Bacteria,1VSB2@1239|Firmicutes,24ZFW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02632	1121115.AXVN01000016_gene3683	0.0	1450.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3XYTU@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
PKFBPKFJ_02633	457412.RSAG_02368	1.72e-215	595.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,3WHV4@541000|Ruminococcaceae	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
PKFBPKFJ_02634	1121115.AXVN01000016_gene3681	0.0	1014.0	2EX8G@1|root,33QJ9@2|Bacteria,1VTVN@1239|Firmicutes,25FHM@186801|Clostridia,3Y0FY@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02635	1121115.AXVN01000016_gene3680	0.0	973.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3XYZ0@572511|Blautia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
PKFBPKFJ_02636	457412.RSAG_02371	0.0	1438.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3WGTG@541000|Ruminococcaceae	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
PKFBPKFJ_02637	1121115.AXVN01000016_gene3678	1.18e-108	313.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,3Y03J@572511|Blautia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
PKFBPKFJ_02638	457412.RSAG_02373	3.27e-227	625.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3WGPQ@541000|Ruminococcaceae	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
PKFBPKFJ_02639	457412.RSAG_02374	7.59e-150	423.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,3WICN@541000|Ruminococcaceae	186801|Clostridia	S	zinc metallopeptidase	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
PKFBPKFJ_02640	457412.RSAG_02375	0.0	900.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,3WGKM@541000|Ruminococcaceae	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
PKFBPKFJ_02641	1121115.AXVN01000016_gene3674	2.2e-252	692.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3XZJW@572511|Blautia	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
PKFBPKFJ_02642	457412.RSAG_02377	2.3e-173	484.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,3WJ4X@541000|Ruminococcaceae	186801|Clostridia	T	serine threonine protein phosphatase	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
PKFBPKFJ_02643	1121115.AXVN01000016_gene3672	0.0	1295.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3XZC8@572511|Blautia	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
PKFBPKFJ_02644	457412.RSAG_02379	3.21e-211	583.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,3WGGY@541000|Ruminococcaceae	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
PKFBPKFJ_02645	457412.RSAG_02380	8.05e-157	440.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3WISD@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the ribulose-phosphate 3-epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
PKFBPKFJ_02646	457412.RSAG_02381	5.77e-160	449.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3WJUT@541000|Ruminococcaceae	186801|Clostridia	H	thiamine pyrophosphokinase	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
PKFBPKFJ_02647	1121115.AXVN01000016_gene3658	5.7e-260	712.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3XZ6D@572511|Blautia	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
PKFBPKFJ_02648	457412.RSAG_02383	8.81e-241	662.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,3WH7A@541000|Ruminococcaceae	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
PKFBPKFJ_02649	457412.RSAG_02384	2.79e-102	295.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,3WJCZ@541000|Ruminococcaceae	186801|Clostridia	K	Belongs to the MraZ family	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
PKFBPKFJ_02650	1121115.AXVN01000016_gene3655	1.27e-222	613.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3XYP8@572511|Blautia	186801|Clostridia	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
PKFBPKFJ_02651	1121115.AXVN01000016_gene3654	1.11e-125	358.0	2E3U8@1|root,32YRK@2|Bacteria,1VEYB@1239|Firmicutes,24QRX@186801|Clostridia,3Y079@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
PKFBPKFJ_02652	457412.RSAG_02387	0.0	1377.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WI1C@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein dimerisation domain	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
PKFBPKFJ_02653	457412.RSAG_02388	0.0	1190.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3WGI4@541000|Ruminococcaceae	186801|Clostridia	M	Penicillin-binding Protein	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
PKFBPKFJ_02654	1121115.AXVN01000016_gene3651	4.74e-217	600.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3XZ7U@572511|Blautia	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
PKFBPKFJ_02655	1121115.AXVN01000016_gene3650	0.0	900.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3XYZG@572511|Blautia	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
PKFBPKFJ_02656	457412.RSAG_02391	4.12e-253	695.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3WHWW@541000|Ruminococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
PKFBPKFJ_02657	457412.RSAG_02392	1.68e-313	853.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3WG8Y@541000|Ruminococcaceae	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA2	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
PKFBPKFJ_02658	457412.RSAG_02393	1.37e-204	573.0	COG1589@1|root,COG1589@2|Bacteria,1V34X@1239|Firmicutes,248RF@186801|Clostridia,3WMQV@541000|Ruminococcaceae	186801|Clostridia	M	COG1589 Cell division septal protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
PKFBPKFJ_02659	457412.RSAG_02394	4.37e-266	731.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3WH3G@541000|Ruminococcaceae	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
PKFBPKFJ_02660	1121115.AXVN01000016_gene3645	1.19e-71	215.0	2DP3R@1|root,330E2@2|Bacteria,1VEPT@1239|Firmicutes,24QJB@186801|Clostridia,3Y0IT@572511|Blautia	186801|Clostridia	S	COG NOG16856 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
PKFBPKFJ_02661	1121115.AXVN01000015_gene3701	1.08e-107	311.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,3XZXW@572511|Blautia	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
PKFBPKFJ_02662	457412.RSAG_02397	6.11e-36	122.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,3WMNQ@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal protein L35	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
PKFBPKFJ_02663	1121115.AXVN01000015_gene3702	3.98e-72	217.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3Y03U@572511|Blautia	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
PKFBPKFJ_02664	1121115.AXVN01000015_gene3704	3.62e-268	735.0	COG0683@1|root,COG0683@2|Bacteria,1TPQ2@1239|Firmicutes,248H1@186801|Clostridia,3XZ26@572511|Blautia	186801|Clostridia	E	COG COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component	braC	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
PKFBPKFJ_02665	1121115.AXVN01000015_gene3705	3.6e-189	528.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,3XYQM@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PKFBPKFJ_02666	1121115.AXVN01000015_gene3706	4.88e-232	641.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia,3XYTB@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
PKFBPKFJ_02667	1121115.AXVN01000015_gene3707	2.49e-179	499.0	COG0411@1|root,COG0411@2|Bacteria,1TR0P@1239|Firmicutes,2490B@186801|Clostridia,3XZSC@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
PKFBPKFJ_02668	1121115.AXVN01000015_gene3708	2.38e-160	450.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,3XZDH@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
PKFBPKFJ_02669	457412.RSAG_02402	3.19e-146	412.0	COG1102@1|root,COG1102@2|Bacteria,1V1PJ@1239|Firmicutes,24GMN@186801|Clostridia,3WITW@541000|Ruminococcaceae	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
PKFBPKFJ_02670	457412.RSAG_02403	8.33e-311	847.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,3WGT0@541000|Ruminococcaceae	186801|Clostridia	L	ATPase, AAA family	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
PKFBPKFJ_02671	1121115.AXVN01000015_gene3717	2.95e-117	335.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia,3Y078@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
PKFBPKFJ_02672	1121115.AXVN01000015_gene3718	1.28e-225	621.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,3XYHJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
PKFBPKFJ_02673	457412.RSAG_02406	2.26e-153	432.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,3WKI6@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
PKFBPKFJ_02674	1121115.AXVN01000015_gene3720	2.08e-165	463.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24H9B@186801|Clostridia,3XZX4@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
PKFBPKFJ_02675	1121115.AXVN01000015_gene3721	1.71e-241	664.0	COG1879@1|root,COG1879@2|Bacteria,1V3FA@1239|Firmicutes,24G5Q@186801|Clostridia,3Y1NU@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
PKFBPKFJ_02676	1121115.AXVN01000015_gene3722	0.0	933.0	COG2972@1|root,COG2972@2|Bacteria,1TSF9@1239|Firmicutes,2499Y@186801|Clostridia,3Y15R@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
PKFBPKFJ_02677	1121115.AXVN01000015_gene3723	0.0	1043.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,24AFC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
PKFBPKFJ_02678	1121115.AXVN01000015_gene3724	6.93e-261	715.0	COG4213@1|root,COG4213@2|Bacteria,1UNTA@1239|Firmicutes	1239|Firmicutes	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
PKFBPKFJ_02679	1121115.AXVN01000015_gene3725	1.97e-255	700.0	COG4213@1|root,COG4213@2|Bacteria,1TR3Q@1239|Firmicutes,2482X@186801|Clostridia,3Y2A7@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10546	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	Peripla_BP_4
PKFBPKFJ_02680	1121115.AXVN01000015_gene3726	0.0	989.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3Y18A@572511|Blautia	186801|Clostridia	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10548	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.5	-	-	ABC_tran
PKFBPKFJ_02681	457412.RSAG_02415	1.12e-265	729.0	COG4214@1|root,COG4214@2|Bacteria,1VU1F@1239|Firmicutes,24XS9@186801|Clostridia,3WGFE@541000|Ruminococcaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	xylH	-	-	ko:K10547	ko02010,map02010	M00216	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.5	-	-	BPD_transp_2
PKFBPKFJ_02682	1121115.AXVN01000015_gene3728	6.15e-185	513.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,3XYKS@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
PKFBPKFJ_02683	1121115.AXVN01000015_gene3729	2.4e-65	199.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,3Y07E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
PKFBPKFJ_02684	1121115.AXVN01000015_gene3730	0.0	2200.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3XZCD@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PKFBPKFJ_02686	1121115.AXVN01000015_gene3731	5.77e-245	672.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,247RJ@186801|Clostridia,3XZQB@572511|Blautia	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
PKFBPKFJ_02687	457412.RSAG_02421	0.0	1519.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,3WGBC@541000|Ruminococcaceae	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
PKFBPKFJ_02688	457412.RSAG_02422	2.38e-222	612.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,3WSMJ@541000|Ruminococcaceae	186801|Clostridia	K	PFAM AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
PKFBPKFJ_02689	457412.RSAG_02423	2.96e-316	860.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,248X0@186801|Clostridia,3WIWK@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
PKFBPKFJ_02690	457412.RSAG_02424	8.19e-212	585.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,3WHPR@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PKFBPKFJ_02691	1121115.AXVN01000015_gene3736	4.82e-188	523.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,3Y0FC@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PKFBPKFJ_02692	1121115.AXVN01000015_gene3737	1.1e-153	432.0	COG5578@1|root,COG5578@2|Bacteria,1V5CK@1239|Firmicutes,24IZD@186801|Clostridia,3Y1SW@572511|Blautia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
PKFBPKFJ_02693	1121115.AXVN01000015_gene3738	0.0	1518.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,3XYN9@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
PKFBPKFJ_02694	1121115.AXVN01000015_gene3739	0.0	1215.0	COG2972@1|root,COG2972@2|Bacteria,1VS09@1239|Firmicutes,24AV3@186801|Clostridia,3Y1HV@572511|Blautia	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
PKFBPKFJ_02695	1121115.AXVN01000015_gene3740	2.1e-165	464.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UUUY@1239|Firmicutes,25KCT@186801|Clostridia,3Y1GV@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
PKFBPKFJ_02696	1121115.AXVN01000015_gene3741	3.42e-297	811.0	COG1653@1|root,COG1653@2|Bacteria,1TRAX@1239|Firmicutes,2497E@186801|Clostridia,3Y0JS@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
PKFBPKFJ_02697	1121115.AXVN01000015_gene3742	1.25e-207	575.0	COG1175@1|root,COG1175@2|Bacteria,1UZE5@1239|Firmicutes,25MIN@186801|Clostridia,3Y15U@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_02698	1121115.AXVN01000015_gene3743	6.12e-194	538.0	COG0395@1|root,COG0395@2|Bacteria,1TSM1@1239|Firmicutes,25C4V@186801|Clostridia,3Y1GS@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_02699	1121115.AXVN01000015_gene3744	0.0	1422.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia,3Y2CQ@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 31	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
PKFBPKFJ_02700	1121115.AXVN01000015_gene3745	0.0	1333.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y0XI@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
PKFBPKFJ_02701	457412.RSAG_02428	2.82e-139	394.0	COG0789@1|root,COG0789@2|Bacteria,1V1M9@1239|Firmicutes,24FUE@186801|Clostridia,3WS7D@541000|Ruminococcaceae	186801|Clostridia	K	Domain of unknown function (DUF1836)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
PKFBPKFJ_02702	457412.RSAG_03505	6.29e-92	278.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,24AH4@186801|Clostridia,3WGYW@541000|Ruminococcaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
PKFBPKFJ_02703	457412.RSAG_03505	1.65e-160	460.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,24AH4@186801|Clostridia,3WGYW@541000|Ruminococcaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
PKFBPKFJ_02704	457412.RSAG_04748	1.92e-97	283.0	COG0745@1|root,COG0745@2|Bacteria,1VH87@1239|Firmicutes,24T6J@186801|Clostridia,3WQ3D@541000|Ruminococcaceae	186801|Clostridia	KT	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
PKFBPKFJ_02705	1121115.AXVN01000083_gene2467	1.73e-170	477.0	COG1961@1|root,COG1961@2|Bacteria,1VU49@1239|Firmicutes,24ZW8@186801|Clostridia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase
PKFBPKFJ_02706	457412.RSAG_00572	3.13e-252	691.0	COG1686@1|root,COG1686@2|Bacteria,1UYI0@1239|Firmicutes,24A51@186801|Clostridia,3WPRS@541000|Ruminococcaceae	186801|Clostridia	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S11
PKFBPKFJ_02707	457412.RSAG_00573	3.62e-121	345.0	28KKS@1|root,2ZA5I@2|Bacteria,1V11Y@1239|Firmicutes,24EK5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02708	457412.RSAG_00574	3.63e-270	741.0	COG0577@1|root,COG0577@2|Bacteria,1TS8R@1239|Firmicutes,24EBA@186801|Clostridia	186801|Clostridia	V	MacB-like periplasmic core domain	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
PKFBPKFJ_02709	1121115.AXVN01000083_gene2471	3.39e-165	462.0	COG1136@1|root,COG1136@2|Bacteria,1V0UF@1239|Firmicutes,24E8G@186801|Clostridia,3Y1CN@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PKFBPKFJ_02710	457412.RSAG_00576	1.88e-190	530.0	COG0845@1|root,COG0845@2|Bacteria,1U20J@1239|Firmicutes,24A0Q@186801|Clostridia	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02711	457412.RSAG_00577	5.83e-251	689.0	COG5002@1|root,COG5002@2|Bacteria,1TPB6@1239|Firmicutes,24AV5@186801|Clostridia,3WH3Q@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase- DNA gyrase B	-	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
PKFBPKFJ_02712	1121115.AXVN01000083_gene2474	5.69e-171	476.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3XZCU@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K18349	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_02713	1121115.AXVN01000083_gene2475	3.4e-43	140.0	COG3655@1|root,COG3655@2|Bacteria,1UVUY@1239|Firmicutes,25M4Q@186801|Clostridia,3Y275@572511|Blautia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
PKFBPKFJ_02714	457412.RSAG_00580	5.69e-262	720.0	COG0791@1|root,COG0791@2|Bacteria,1UKHZ@1239|Firmicutes,25FXH@186801|Clostridia,3WHIZ@541000|Ruminococcaceae	186801|Clostridia	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP
PKFBPKFJ_02715	1121115.AXVN01000083_gene2477	1.19e-07	50.8	2C0GW@1|root,33C02@2|Bacteria,1VQ7E@1239|Firmicutes,24XF2@186801|Clostridia,3Y224@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02717	457412.RSAG_00582	0.0	1273.0	COG1669@1|root,COG1669@2|Bacteria,1UKI0@1239|Firmicutes,25FXI@186801|Clostridia	186801|Clostridia	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF4316,YodL
PKFBPKFJ_02718	1121115.AXVN01000083_gene2479	5.43e-183	509.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,247R1@186801|Clostridia,3XZBU@572511|Blautia	186801|Clostridia	D	CobQ CobB MinD ParA nucleotide binding domain protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
PKFBPKFJ_02719	1121115.AXVN01000083_gene2480	5.25e-79	237.0	COG0582@1|root,COG0582@2|Bacteria,1VBGF@1239|Firmicutes,24NRM@186801|Clostridia	186801|Clostridia	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02720	457412.RSAG_00585	5.65e-136	386.0	COG1277@1|root,305HC@2|Bacteria,1TV0H@1239|Firmicutes,259V5@186801|Clostridia,3WR6P@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02721	411459.RUMOBE_00585	1.64e-98	285.0	COG0745@1|root,COG0745@2|Bacteria,1V65U@1239|Firmicutes,24HUB@186801|Clostridia,3Y0QH@572511|Blautia	186801|Clostridia	KT	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
PKFBPKFJ_02722	411459.RUMOBE_00586	1.93e-79	236.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,24N11@186801|Clostridia,3Y08G@572511|Blautia	186801|Clostridia	K	beta-lactamase (penicillinase) repressor	blaI	-	-	ko:K02171	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
PKFBPKFJ_02723	411459.RUMOBE_00587	0.0	1171.0	COG2602@1|root,COG4219@1|root,COG2602@2|Bacteria,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,3XYWY@572511|Blautia	186801|Clostridia	KTV	Psort location CytoplasmicMembrane, score	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56,Transpeptidase
PKFBPKFJ_02724	457412.RSAG_00588	3.34e-307	836.0	28IBJ@1|root,2Z8XY@2|Bacteria,1UCWW@1239|Firmicutes,24DUG@186801|Clostridia,3WKA7@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02725	457412.RSAG_00589	9.23e-292	795.0	28IBJ@1|root,2Z8E0@2|Bacteria,1UYB9@1239|Firmicutes,24BIZ@186801|Clostridia,3WP1C@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02726	457412.RSAG_00590	0.0	1380.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,248PI@186801|Clostridia,3WH22@541000|Ruminococcaceae	186801|Clostridia	M	NTF2-like N-terminal transpeptidase domain	pbpC	-	3.4.16.4	ko:K05515,ko:K21467	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
PKFBPKFJ_02727	1121115.AXVN01000003_gene1516	3.71e-53	166.0	2E255@1|root,32XC6@2|Bacteria,1VASU@1239|Firmicutes,25PWU@186801|Clostridia,3Y1UH@572511|Blautia	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
PKFBPKFJ_02728	411459.RUMOBE_00600	0.0	1013.0	COG1669@1|root,COG4227@1|root,COG4734@1|root,COG1669@2|Bacteria,COG4227@2|Bacteria,COG4734@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,3XYTM@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ArdA,DUF3849,DUF4316,Peptidase_M78,YodL,zf-CHC2
PKFBPKFJ_02729	742765.HMPREF9457_01320	0.0	1030.0	COG1669@1|root,COG2003@1|root,COG4227@1|root,COG4734@1|root,COG1669@2|Bacteria,COG2003@2|Bacteria,COG4227@2|Bacteria,COG4734@2|Bacteria,1TQN4@1239|Firmicutes,2482H@186801|Clostridia,27W0W@189330|Dorea	186801|Clostridia	L	Protein of unknown function (DUF3849)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3849,Peptidase_M78,YodL
PKFBPKFJ_02730	500632.CLONEX_02426	4.1e-211	587.0	COG0553@1|root,COG0553@2|Bacteria,1V3WS@1239|Firmicutes,24IXD@186801|Clostridia	186801|Clostridia	KL	reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02733	1121115.AXVN01000066_gene3218	8.06e-165	461.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,3XZ8R@572511|Blautia	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
PKFBPKFJ_02734	1121115.AXVN01000066_gene3219	1.12e-246	677.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3XYPY@572511|Blautia	186801|Clostridia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
PKFBPKFJ_02735	1121115.AXVN01000066_gene3220	1.62e-225	620.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,3XZ6W@572511|Blautia	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
PKFBPKFJ_02736	457412.RSAG_01972	6.29e-100	290.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3WKHF@541000|Ruminococcaceae	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
PKFBPKFJ_02737	457412.RSAG_01973	3.93e-162	455.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,3WJ9X@541000|Ruminococcaceae	186801|Clostridia	O	Universal bacterial protein YeaZ	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
PKFBPKFJ_02738	1121115.AXVN01000066_gene3223	1.05e-102	296.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3Y003@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
PKFBPKFJ_02739	1121115.AXVN01000066_gene3224	9.9e-126	357.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
PKFBPKFJ_02740	457412.RSAG_01976	8.73e-154	432.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,3WIHN@541000|Ruminococcaceae	186801|Clostridia	S	YigZ family	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
PKFBPKFJ_02741	457412.RSAG_01977	0.0	1583.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia,3WSNS@541000|Ruminococcaceae	186801|Clostridia	M	Transglycosylase	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
PKFBPKFJ_02742	1121115.AXVN01000066_gene3227	1.18e-224	619.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3XYHF@572511|Blautia	186801|Clostridia	GK	Psort location Cytoplasmic, score	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
PKFBPKFJ_02743	1121115.AXVN01000066_gene3228	4.97e-220	607.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,3XZ5K@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
PKFBPKFJ_02744	457412.RSAG_01980	0.0	1207.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,3WH2A@541000|Ruminococcaceae	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
PKFBPKFJ_02745	1121115.AXVN01000066_gene3230	0.0	1251.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XYZH@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
PKFBPKFJ_02746	1121115.AXVN01000066_gene3231	0.0	971.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia,3XYIV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
PKFBPKFJ_02747	1121115.AXVN01000066_gene3232	3.02e-178	496.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3XZZF@572511|Blautia	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
PKFBPKFJ_02748	457412.RSAG_01984	2.08e-200	554.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,3WJDK@541000|Ruminococcaceae	186801|Clostridia	S	Carbon-nitrogen hydrolase	nit	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
PKFBPKFJ_02749	457412.RSAG_01985	8.3e-253	692.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,3WGSG@541000|Ruminococcaceae	186801|Clostridia	M	UDP-glucose 4-epimerase	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
PKFBPKFJ_02750	1121115.AXVN01000066_gene3236	6.51e-271	740.0	COG2334@1|root,COG2334@2|Bacteria,1UXS1@1239|Firmicutes,25MC4@186801|Clostridia,3XZ7J@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	APH
PKFBPKFJ_02751	457412.RSAG_01987	7.17e-232	637.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3WSRR@541000|Ruminococcaceae	186801|Clostridia	M	Nucleotidyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
PKFBPKFJ_02752	457412.RSAG_01988	1.35e-203	564.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3WN1I@541000|Ruminococcaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_02753	1121115.AXVN01000092_gene69	1.35e-211	586.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3XYIT@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_02754	1121115.AXVN01000092_gene70	6.52e-310	843.0	COG1653@1|root,COG1653@2|Bacteria,1TPBF@1239|Firmicutes,24920@186801|Clostridia	186801|Clostridia	G	ABC transporter, solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
PKFBPKFJ_02755	1121115.AXVN01000092_gene71	5.28e-221	609.0	COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,247WN@186801|Clostridia,3XZJ7@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PKFBPKFJ_02756	457412.RSAG_01992	9.33e-313	851.0	COG1653@1|root,COG1653@2|Bacteria,1TPBF@1239|Firmicutes,24920@186801|Clostridia,3WP3X@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
PKFBPKFJ_02757	457412.RSAG_01993	0.0	864.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WGB6@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,sCache_like
PKFBPKFJ_02758	1121115.AXVN01000092_gene74	7.77e-159	445.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,3XYH5@572511|Blautia	186801|Clostridia	T	positive response regulator for pho regulon	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_02759	1121115.AXVN01000092_gene75	0.0	1096.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3XYUW@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
PKFBPKFJ_02760	1121115.AXVN01000092_gene76	5.11e-107	309.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia,3XZZN@572511|Blautia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
PKFBPKFJ_02761	1121115.AXVN01000092_gene77	0.0	1808.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,3XYMW@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
PKFBPKFJ_02762	1121115.AXVN01000092_gene78	6.65e-204	567.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,3Y281@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02763	457412.RSAG_01999	8.02e-75	224.0	COG5561@1|root,COG5561@2|Bacteria,1VBDY@1239|Firmicutes,259Y8@186801|Clostridia,3WQWE@541000|Ruminococcaceae	186801|Clostridia	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
PKFBPKFJ_02764	457412.RSAG_02000	2.89e-173	484.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,3WHNG@541000|Ruminococcaceae	186801|Clostridia	HP	ABC transporter	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
PKFBPKFJ_02765	457412.RSAG_02001	5.12e-245	674.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,248IS@186801|Clostridia,3WIHA@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
PKFBPKFJ_02766	457412.RSAG_02002	1.2e-245	677.0	COG0614@1|root,COG0614@2|Bacteria,1TSAF@1239|Firmicutes,24ATS@186801|Clostridia,3WI3J@541000|Ruminococcaceae	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
PKFBPKFJ_02767	1121115.AXVN01000074_gene2300	7.95e-140	396.0	2DG4Z@1|root,2ZUIM@2|Bacteria,1V47V@1239|Firmicutes,24HN9@186801|Clostridia,3Y0J3@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
PKFBPKFJ_02768	457412.RSAG_02004	2.51e-198	550.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3WGWZ@541000|Ruminococcaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_02769	457412.RSAG_02005	1.59e-78	234.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,3WJYT@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
PKFBPKFJ_02770	1121115.AXVN01000074_gene2291	1.42e-212	586.0	COG4667@1|root,COG4667@2|Bacteria,1TQ9W@1239|Firmicutes,2485C@186801|Clostridia,3Y02V@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
PKFBPKFJ_02771	1121115.AXVN01000074_gene2290	6.61e-188	522.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,3XYTK@572511|Blautia	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.7.1.49,2.7.4.7	ko:K00941	ko00730,ko01100,map00730,map01100	M00127	R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
PKFBPKFJ_02772	457412.RSAG_02014	2.59e-143	405.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,3WIVU@541000|Ruminococcaceae	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
PKFBPKFJ_02773	1121115.AXVN01000074_gene2288	8.89e-26	96.3	COG1453@1|root,COG1453@2|Bacteria	2|Bacteria	S	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
PKFBPKFJ_02774	1121115.AXVN01000074_gene2287	0.0	880.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3XYZK@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
PKFBPKFJ_02775	457412.RSAG_02016	1.14e-87	257.0	2C3ER@1|root,32RC8@2|Bacteria,1V7SK@1239|Firmicutes,24U80@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02776	457412.RSAG_02018	1.06e-37	127.0	COG1595@1|root,COG1595@2|Bacteria,1V1EX@1239|Firmicutes,24BBF@186801|Clostridia,3WJCJ@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
PKFBPKFJ_02777	457412.RSAG_02807	4.67e-52	164.0	COG1879@1|root,COG1879@2|Bacteria,1VX4B@1239|Firmicutes,251P0@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02778	1121115.AXVN01000103_gene865	6.46e-83	245.0	COG3682@1|root,COG3682@2|Bacteria,1VEJ8@1239|Firmicutes	1239|Firmicutes	K	repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
PKFBPKFJ_02779	457412.RSAG_02805	1.92e-159	446.0	COG0454@1|root,COG0456@2|Bacteria,1V1I9@1239|Firmicutes,24GXQ@186801|Clostridia,3WIY4@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
PKFBPKFJ_02780	457412.RSAG_02804	0.0	1403.0	COG2234@1|root,COG2234@2|Bacteria,1TRWH@1239|Firmicutes,24BM1@186801|Clostridia,3WI61@541000|Ruminococcaceae	186801|Clostridia	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
PKFBPKFJ_02781	457412.RSAG_02803	0.0	1382.0	COG0451@1|root,COG0451@2|Bacteria,1UYUX@1239|Firmicutes,24CYP@186801|Clostridia,3WKD2@541000|Ruminococcaceae	186801|Clostridia	GM	Domain of unknown function (DUF4118)	-	-	5.1.3.2	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,RmlD_sub_bind
PKFBPKFJ_02782	457412.RSAG_02802	4.17e-205	568.0	28H6W@1|root,2Z7J7@2|Bacteria,1TPV9@1239|Firmicutes,24CD2@186801|Clostridia,3WMQ4@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02783	457412.RSAG_02801	0.0	1233.0	COG4878@1|root,COG4878@2|Bacteria,1TT2Y@1239|Firmicutes,24A4C@186801|Clostridia,3WIQH@541000|Ruminococcaceae	186801|Clostridia	S	Uncharacterised protein conserved in bacteria (DUF2194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2194
PKFBPKFJ_02784	457412.RSAG_02800	0.0	973.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,24BAM@186801|Clostridia,3WGGZ@541000|Ruminococcaceae	186801|Clostridia	M	Domain of unknown function (DUF3492)	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glycos_transf_1
PKFBPKFJ_02785	457412.RSAG_02799	0.0	930.0	COG4267@1|root,COG4267@2|Bacteria,1TRZE@1239|Firmicutes,24EQ7@186801|Clostridia,3WKMX@541000|Ruminococcaceae	186801|Clostridia	S	Putative exopolysaccharide Exporter (EPS-E)	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
PKFBPKFJ_02786	457412.RSAG_02798	0.0	1162.0	COG5337@1|root,COG5337@2|Bacteria,1U5H9@1239|Firmicutes,249YX@186801|Clostridia,3WI9H@541000|Ruminococcaceae	186801|Clostridia	M	CotH kinase protein	-	-	-	ko:K06330	-	-	-	-	ko00000	-	-	-	CotH
PKFBPKFJ_02787	457412.RSAG_02797	8.7e-179	498.0	COG5036@1|root,COG5036@2|Bacteria,1TYFN@1239|Firmicutes,24AGZ@186801|Clostridia,3WJCF@541000|Ruminococcaceae	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
PKFBPKFJ_02788	457412.RSAG_02796	2.78e-148	418.0	COG1285@1|root,COG1285@2|Bacteria,1TRUW@1239|Firmicutes,248G4@186801|Clostridia,3WHWK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
PKFBPKFJ_02789	457412.RSAG_02795	0.0	926.0	COG1874@1|root,COG1874@2|Bacteria,1TRPS@1239|Firmicutes,24AH9@186801|Clostridia,3WIPR@541000|Ruminococcaceae	186801|Clostridia	G	Domain of unknown function (DUF4832)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,Glyco_hydro_42
PKFBPKFJ_02790	1121115.AXVN01000103_gene858	3.37e-126	365.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3Y10N@572511|Blautia	186801|Clostridia	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
PKFBPKFJ_02791	1121115.AXVN01000103_gene858	6.38e-85	258.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3Y10N@572511|Blautia	186801|Clostridia	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
PKFBPKFJ_02792	1121115.AXVN01000103_gene855	2.61e-112	322.0	COG5423@1|root,COG5423@2|Bacteria,1VBHK@1239|Firmicutes,24XGW@186801|Clostridia,3Y0MP@572511|Blautia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
PKFBPKFJ_02793	1121115.AXVN01000012_gene3147	4.97e-138	390.0	COG1309@1|root,COG1309@2|Bacteria,1U1ZX@1239|Firmicutes,24ERU@186801|Clostridia,3Y2CF@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PKFBPKFJ_02794	1121115.AXVN01000012_gene3146	3.63e-272	745.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3Y03X@572511|Blautia	186801|Clostridia	C	COG COG1454 Alcohol dehydrogenase, class IV	fucO	-	1.1.1.77	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	-	R01781,R02257	RC00087,RC00099	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
PKFBPKFJ_02795	292563.Cyast_0943	4.47e-34	119.0	COG4115@1|root,COG4115@2|Bacteria,1G85U@1117|Cyanobacteria	1117|Cyanobacteria	S	TIGRFAM toxin-antitoxin system, toxin component, Txe YoeB family	-	-	-	ko:K19158	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	YoeB_toxin
PKFBPKFJ_02796	1410628.JNKS01000011_gene2644	9.68e-31	110.0	COG3077@1|root,COG3077@2|Bacteria,1TU5Z@1239|Firmicutes,25N1P@186801|Clostridia,27QG0@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Addiction module antitoxin, RelB DinJ family	-	-	-	-	-	-	-	-	-	-	-	-	RelB
PKFBPKFJ_02797	457412.RSAG_02778	2.9e-143	404.0	COG2357@1|root,COG2357@2|Bacteria,1UZBZ@1239|Firmicutes,24FD2@186801|Clostridia,3WJCI@541000|Ruminococcaceae	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
PKFBPKFJ_02798	457412.RSAG_02775	9.94e-269	738.0	COG3633@1|root,COG3633@2|Bacteria,1TPD2@1239|Firmicutes,25CGY@186801|Clostridia,3WHQY@541000|Ruminococcaceae	186801|Clostridia	E	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)	sstT	-	-	ko:K07862	-	-	-	-	ko00000,ko02000	2.A.23.4	-	-	SDF
PKFBPKFJ_02799	1235802.C823_05668	1.87e-43	142.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,25X1K@186806|Eubacteriaceae	186801|Clostridia	K	sporulation transcriptional regulator SpoIIID	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
PKFBPKFJ_02800	457412.RSAG_02755	7.6e-212	583.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,24F6M@186801|Clostridia,3WJRY@541000|Ruminococcaceae	186801|Clostridia	S	Putative esterase	-	-	-	ko:K03930	-	-	-	-	ko00000,ko01000	-	CE1	-	Esterase
PKFBPKFJ_02801	457412.RSAG_02754	1.33e-32	114.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia,3WGAE@541000|Ruminococcaceae	186801|Clostridia	G	Alpha-L-arabinofuranosidase	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
PKFBPKFJ_02802	742765.HMPREF9457_03059	1.86e-235	651.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,24AH4@186801|Clostridia,27W37@189330|Dorea	186801|Clostridia	L	COG COG3547 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
PKFBPKFJ_02803	1121115.AXVN01000004_gene1962	1.7e-60	186.0	COG1366@1|root,COG1366@2|Bacteria,1VB77@1239|Firmicutes,24T7M@186801|Clostridia,3Y25G@572511|Blautia	186801|Clostridia	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
PKFBPKFJ_02804	457412.RSAG_00395	1.03e-91	268.0	COG2172@1|root,COG2172@2|Bacteria,1VAPM@1239|Firmicutes,24J9J@186801|Clostridia,3WKBK@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
PKFBPKFJ_02805	1121115.AXVN01000004_gene1960	6.85e-266	733.0	COG4260@1|root,COG4260@2|Bacteria,1TRYU@1239|Firmicutes,24901@186801|Clostridia,3Y16V@572511|Blautia	186801|Clostridia	S	SPFH domain-Band 7 family	-	-	-	-	-	-	-	-	-	-	-	-	Band_7_1,SHOCT
PKFBPKFJ_02806	457412.RSAG_00393	9.23e-270	737.0	COG1996@1|root,COG1996@2|Bacteria,1UI9I@1239|Firmicutes,248XK@186801|Clostridia,3WHNV@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02807	1121115.AXVN01000004_gene1958	2.35e-182	509.0	COG1512@1|root,COG1512@2|Bacteria,1V2US@1239|Firmicutes,257P6@186801|Clostridia,3Y1PM@572511|Blautia	186801|Clostridia	S	TPM domain	-	-	-	-	-	-	-	-	-	-	-	-	TPM_phosphatase
PKFBPKFJ_02808	457412.RSAG_00391	2.29e-178	497.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,3WJ55@541000|Ruminococcaceae	186801|Clostridia	GM	Transport permease protein	pyrL	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
PKFBPKFJ_02809	1121115.AXVN01000004_gene1956	5.19e-169	473.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,3XYUG@572511|Blautia	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score 9.49	rfbB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_02810	457412.RSAG_00389	4.21e-266	728.0	COG1835@1|root,COG1835@2|Bacteria,1VEDZ@1239|Firmicutes,259Z5@186801|Clostridia,3WQXI@541000|Ruminococcaceae	186801|Clostridia	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
PKFBPKFJ_02811	1121115.AXVN01000004_gene1954	1.25e-268	735.0	COG0438@1|root,COG0438@2|Bacteria,1TRCM@1239|Firmicutes,24B86@186801|Clostridia,3Y04U@572511|Blautia	186801|Clostridia	M	Glycosyltransferase, group 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
PKFBPKFJ_02812	1121115.AXVN01000004_gene1953	1.92e-270	737.0	COG0438@1|root,COG0438@2|Bacteria,1TPG9@1239|Firmicutes,24EAP@186801|Clostridia	186801|Clostridia	M	Stealth protein CR2, conserved region 2	-	-	-	-	-	-	-	-	-	-	-	-	Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
PKFBPKFJ_02813	1121115.AXVN01000004_gene1952	0.0	862.0	COG1887@1|root,COG1887@2|Bacteria,1V2N4@1239|Firmicutes,24FU6@186801|Clostridia,3Y1R0@572511|Blautia	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
PKFBPKFJ_02814	1121115.AXVN01000004_gene1951	2.94e-97	282.0	COG0615@1|root,COG0615@2|Bacteria,1V3KY@1239|Firmicutes,24HAQ@186801|Clostridia	186801|Clostridia	IM	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CTP_transf_like
PKFBPKFJ_02815	457412.RSAG_00384	1.98e-301	822.0	COG1887@1|root,COG1887@2|Bacteria,1V2N4@1239|Firmicutes,24FU6@186801|Clostridia,3WR0Q@541000|Ruminococcaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
PKFBPKFJ_02816	1121115.AXVN01000004_gene1949	0.0	1958.0	COG0438@1|root,COG1887@1|root,COG0438@2|Bacteria,COG1887@2|Bacteria,1TSEW@1239|Firmicutes,25KH4@186801|Clostridia,3Y05H@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Glyphos_transf
PKFBPKFJ_02817	1121115.AXVN01000004_gene1948	1.95e-175	490.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,3XZ0B@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
PKFBPKFJ_02818	1121115.AXVN01000004_gene1947	7.57e-61	186.0	COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes,25P5S@186801|Clostridia,3Y0IV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PRC
PKFBPKFJ_02819	1121115.AXVN01000004_gene1946	4.38e-102	295.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3XZYK@572511|Blautia	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
PKFBPKFJ_02820	457412.RSAG_00378	0.0	878.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3WGP0@541000|Ruminococcaceae	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
PKFBPKFJ_02821	1121115.AXVN01000004_gene1944	0.0	899.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3XYZV@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	gltA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
PKFBPKFJ_02822	1121115.AXVN01000004_gene1943	4.23e-120	342.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia,3XZXE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
PKFBPKFJ_02823	1121115.AXVN01000004_gene1942	1.15e-116	334.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3Y095@572511|Blautia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
PKFBPKFJ_02824	1121115.AXVN01000004_gene1941	3.66e-132	374.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3XZPQ@572511|Blautia	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
PKFBPKFJ_02825	1121115.AXVN01000004_gene1940	9.73e-230	634.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,3Y032@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
PKFBPKFJ_02826	1121115.AXVN01000090_gene2560	2.83e-62	190.0	COG1598@1|root,COG1598@2|Bacteria,1VH8E@1239|Firmicutes,2586D@186801|Clostridia,3Y0CI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HicB_lk_antitox
PKFBPKFJ_02827	1121115.AXVN01000090_gene2559	4.53e-199	550.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,3XZBG@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
PKFBPKFJ_02828	1121115.AXVN01000090_gene2558	1.37e-64	196.0	2E7YJ@1|root,30FFS@2|Bacteria,1UDZU@1239|Firmicutes,25IU2@186801|Clostridia,3Y1VR@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02829	1121115.AXVN01000054_gene1870	3.72e-158	442.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3XZP9@572511|Blautia	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
PKFBPKFJ_02830	1121115.AXVN01000054_gene1871	3.84e-300	817.0	29WP9@1|root,30IA6@2|Bacteria,1V4GZ@1239|Firmicutes,24HWX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02831	457412.RSAG_02721	0.0	1496.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3WH1C@541000|Ruminococcaceae	186801|Clostridia	F	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	malP_1	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
PKFBPKFJ_02832	1121115.AXVN01000054_gene1873	1.98e-202	561.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24I3P@186801|Clostridia,3Y1VY@572511|Blautia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PKFBPKFJ_02833	457412.RSAG_02719	4.06e-181	506.0	COG3290@1|root,COG3290@2|Bacteria,1VDUW@1239|Firmicutes,24QIG@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PKFBPKFJ_02834	457412.RSAG_02718	4.74e-197	549.0	2EZ41@1|root,33SA8@2|Bacteria,1VSVN@1239|Firmicutes,24XVU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02835	457412.RSAG_02717	7.7e-168	469.0	COG3279@1|root,COG3279@2|Bacteria,1VC9Q@1239|Firmicutes,24PSE@186801|Clostridia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_02836	1121115.AXVN01000054_gene1878	0.0	1050.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PKFBPKFJ_02838	457412.RSAG_02713	3.52e-211	586.0	28K5V@1|root,2Z9UD@2|Bacteria,1V0GM@1239|Firmicutes,24EZ5@186801|Clostridia,3WNRK@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3878)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3878
PKFBPKFJ_02839	457412.RSAG_02712	5.18e-180	502.0	COG2206@1|root,COG2206@2|Bacteria,1V23X@1239|Firmicutes,24GQ5@186801|Clostridia,3WKDD@541000|Ruminococcaceae	186801|Clostridia	T	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
PKFBPKFJ_02840	457412.RSAG_02711	9.47e-128	364.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,3WK2K@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function DUF45	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
PKFBPKFJ_02841	457412.RSAG_02710	1.63e-301	822.0	COG1379@1|root,COG1379@2|Bacteria	2|Bacteria	-	-	yqxK	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF4178,PHP_C,UvrD-helicase,UvrD_C
PKFBPKFJ_02842	1121115.AXVN01000054_gene1886	3.06e-108	311.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,24PEZ@186801|Clostridia,3Y0BJ@572511|Blautia	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
PKFBPKFJ_02843	742740.HMPREF9474_02654	9.31e-44	150.0	COG0794@1|root,COG0794@2|Bacteria,1UYG2@1239|Firmicutes,24DJV@186801|Clostridia,2218B@1506553|Lachnoclostridium	186801|Clostridia	M	SIS domain	hxlB	-	5.3.1.27	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	M00345,M00580	R05339,R09780	RC00377	ko00000,ko00001,ko00002,ko01000	-	-	-	SIS
PKFBPKFJ_02844	742740.HMPREF9474_02646	1.29e-130	378.0	COG1737@1|root,COG1737@2|Bacteria,1V98J@1239|Firmicutes,24K08@186801|Clostridia,220NG@1506553|Lachnoclostridium	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
PKFBPKFJ_02845	742740.HMPREF9474_02647	5.51e-146	422.0	COG1879@1|root,COG1879@2|Bacteria,1V0EN@1239|Firmicutes,24INN@186801|Clostridia,222VW@1506553|Lachnoclostridium	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
PKFBPKFJ_02846	742740.HMPREF9474_02648	1.96e-23	99.8	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,21XJ5@1506553|Lachnoclostridium	186801|Clostridia	P	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
PKFBPKFJ_02847	1121864.OMO_01641	2.34e-85	251.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PKFBPKFJ_02848	665950.HMPREF1025_01479	0.0	1273.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,27K2V@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Elongation factor G, domain IV	-	-	-	ko:K18220	-	-	-	-	br01600,ko00000,ko01504	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU
PKFBPKFJ_02849	665950.HMPREF1025_01478	1.3e-115	331.0	COG1191@1|root,COG1191@2|Bacteria,1V1GF@1239|Firmicutes,249WS@186801|Clostridia,27KFF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
PKFBPKFJ_02850	665950.HMPREF1025_01477	1.75e-87	257.0	COG1595@1|root,COG1595@2|Bacteria,1UYSW@1239|Firmicutes,24CRZ@186801|Clostridia,27MXP@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
PKFBPKFJ_02851	665950.HMPREF1025_01476	3.54e-105	304.0	COG1595@1|root,COG1595@2|Bacteria,1TRPH@1239|Firmicutes,24BTD@186801|Clostridia,27K7G@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
PKFBPKFJ_02852	665950.HMPREF1025_01475	4.1e-250	686.0	COG0468@1|root,COG0468@2|Bacteria,1V9SB@1239|Firmicutes,25E2S@186801|Clostridia,27KVT@186928|unclassified Lachnospiraceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25
PKFBPKFJ_02853	1121864.OMO_01635	9.01e-228	627.0	COG1196@1|root,COG1196@2|Bacteria,1TRNI@1239|Firmicutes,4HHXH@91061|Bacilli,4B4B0@81852|Enterococcaceae	91061|Bacilli	D	Plasmid recombination enzyme	XK26_06135	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PKFBPKFJ_02854	665950.HMPREF1025_01473	7.99e-192	533.0	COG1475@1|root,COG1475@2|Bacteria,1TR7C@1239|Firmicutes,247TW@186801|Clostridia,27J9V@186928|unclassified Lachnospiraceae	186801|Clostridia	K	ParB-like nuclease domain	-	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
PKFBPKFJ_02855	1000569.HMPREF1040_0237	1.99e-48	154.0	COG4443@1|root,COG4443@2|Bacteria,1VEFE@1239|Firmicutes	1239|Firmicutes	S	protein conserved in bacteria	XK26_06125	-	-	-	-	-	-	-	-	-	-	-	PC4
PKFBPKFJ_02856	1121864.OMO_01632	4.17e-55	172.0	2AH2U@1|root,317C4@2|Bacteria,1V7XU@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02857	665950.HMPREF1025_01470	0.0	1221.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27KMV@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_02859	1232453.BAIF02000044_gene3512	1.19e-121	350.0	COG0745@1|root,COG0745@2|Bacteria,1VCS1@1239|Firmicutes,24J1M@186801|Clostridia	186801|Clostridia	KT	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
PKFBPKFJ_02860	1121333.JMLH01000011_gene661	4.77e-55	172.0	2ATI9@1|root,31J23@2|Bacteria,1V7YH@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02862	1232453.BAIF02000044_gene3513	6.3e-90	264.0	COG2197@1|root,COG2197@2|Bacteria,1VF90@1239|Firmicutes,24K9Z@186801|Clostridia	186801|Clostridia	KT	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
PKFBPKFJ_02863	500632.CLONEX_03763	0.0	1270.0	COG1199@1|root,COG1199@2|Bacteria,1TQHQ@1239|Firmicutes,25C6H@186801|Clostridia	186801|Clostridia	L	helicase involved in DNA repair and perhaps also replication	-	-	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Helicase_C_2
PKFBPKFJ_02864	1232453.BAIF02000044_gene3515	1.77e-269	738.0	COG0582@1|root,COG0582@2|Bacteria,1TXU3@1239|Firmicutes,24C0Y@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PKFBPKFJ_02865	1232453.BAIF02000044_gene3516	0.0	1056.0	COG0582@1|root,COG0582@2|Bacteria,1V07B@1239|Firmicutes	1239|Firmicutes	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
PKFBPKFJ_02866	1232453.BAIF02000044_gene3517	0.0	952.0	COG0582@1|root,COG0582@2|Bacteria,1U0FV@1239|Firmicutes,24B44@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PKFBPKFJ_02867	1232453.BAIF02000044_gene3518	8.87e-62	192.0	2D1NJ@1|root,33V76@2|Bacteria,1VUDB@1239|Firmicutes,25051@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02868	553175.POREN0001_0455	4.84e-10	71.2	2BW5H@1|root,2ZPYH@2|Bacteria,4P5HJ@976|Bacteroidetes,2FYX2@200643|Bacteroidia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02869	742733.HMPREF9469_01135	3.81e-277	761.0	2D2CR@1|root,32TCH@2|Bacteria,1VZ3Z@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02871	742765.HMPREF9457_02143	0.0	1404.0	COG0419@1|root,COG1121@1|root,COG0419@2|Bacteria,COG1121@2|Bacteria,1V0RJ@1239|Firmicutes,24EJF@186801|Clostridia	186801|Clostridia	L	ATPase involved in DNA repair	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23
PKFBPKFJ_02872	1235802.C823_01591	0.0	1475.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1VR4T@1239|Firmicutes,24XZV@186801|Clostridia,25ZFR@186806|Eubacteriaceae	186801|Clostridia	MV	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
PKFBPKFJ_02873	1235835.C814_02695	1.06e-187	532.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,3WH9S@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase
PKFBPKFJ_02874	411459.RUMOBE_00594	1.39e-66	204.0	COG0745@1|root,COG0745@2|Bacteria,1UVF6@1239|Firmicutes,25M0N@186801|Clostridia,3Y1TD@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
PKFBPKFJ_02875	457412.RSAG_01897	3.53e-227	625.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3WHZJ@541000|Ruminococcaceae	186801|Clostridia	I	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
PKFBPKFJ_02876	1121115.AXVN01000171_gene912	2.26e-228	632.0	2E2H9@1|root,32XM9@2|Bacteria,1VC5F@1239|Firmicutes,259ZF@186801|Clostridia,3XZVR@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF5067)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5067
PKFBPKFJ_02877	1121115.AXVN01000171_gene911	2.63e-44	143.0	COG2155@1|root,COG2155@2|Bacteria,1TU48@1239|Firmicutes,259I6@186801|Clostridia,3Y0R3@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
PKFBPKFJ_02882	1121115.AXVN01000078_gene2834	2.74e-195	544.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,3XYRQ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
PKFBPKFJ_02885	457412.RSAG_01913	0.0	1331.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3WGAB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk1	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
PKFBPKFJ_02886	457412.RSAG_01914	3.45e-215	595.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3WGMM@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
PKFBPKFJ_02887	1121115.AXVN01000078_gene2831	0.0	903.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3XZQF@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_02888	1121115.AXVN01000078_gene2830	1.5e-197	548.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,3Y0BN@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PKFBPKFJ_02889	457412.RSAG_01920	1.44e-234	647.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,3WJ50@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
PKFBPKFJ_02890	457412.RSAG_01921	1.22e-310	846.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3WICE@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8,TAT_signal
PKFBPKFJ_02891	457412.RSAG_01922	3.99e-134	381.0	COG4720@1|root,COG4720@2|Bacteria,1USKD@1239|Firmicutes,24A2K@186801|Clostridia,3WKAY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
PKFBPKFJ_02892	1121115.AXVN01000078_gene2826	4.83e-276	755.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3XYME@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
PKFBPKFJ_02893	1121115.AXVN01000078_gene2825	0.0	1126.0	28NHG@1|root,2ZBJ9@2|Bacteria,1V1QG@1239|Firmicutes,24GQ1@186801|Clostridia,3Y0RS@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
PKFBPKFJ_02894	457412.RSAG_01925	1.78e-134	381.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3WK21@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_02895	457412.RSAG_01927	3.09e-114	328.0	COG1418@1|root,COG1418@2|Bacteria,1V70P@1239|Firmicutes,24JTJ@186801|Clostridia,3WJN7@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HD
PKFBPKFJ_02896	457412.RSAG_01928	5.5e-284	775.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3WI85@541000|Ruminococcaceae	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct,Flavodoxin_5,Lactamase_B
PKFBPKFJ_02897	457412.RSAG_01929	7.74e-112	328.0	COG5464@1|root,COG5464@2|Bacteria,1TUFY@1239|Firmicutes,259KT@186801|Clostridia,3WQBQ@541000|Ruminococcaceae	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02898	1121115.AXVN01000102_gene3587	8.64e-178	496.0	COG1737@1|root,COG1737@2|Bacteria,1TS9A@1239|Firmicutes,24CDD@186801|Clostridia	186801|Clostridia	K	transcriptional regulator RpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
PKFBPKFJ_02899	1121115.AXVN01000102_gene3586	7.99e-69	207.0	COG1440@1|root,COG1440@2|Bacteria,1VDI5@1239|Firmicutes,25CRE@186801|Clostridia	186801|Clostridia	G	PFAM Phosphotransferase system, lactose cellobiose-specific IIB subunit	-	-	2.7.1.196,2.7.1.205	ko:K02760	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIB
PKFBPKFJ_02900	1121115.AXVN01000102_gene3585	3.03e-312	851.0	COG1455@1|root,COG1455@2|Bacteria,1TP8D@1239|Firmicutes,24808@186801|Clostridia,3Y1VT@572511|Blautia	186801|Clostridia	G	Phosphotransferase system, EIIC	-	-	-	ko:K02761	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko02000	4.A.3.2	-	-	PTS_EIIC
PKFBPKFJ_02901	1121115.AXVN01000102_gene3584	7.28e-71	213.0	COG1447@1|root,COG1447@2|Bacteria,1VEPM@1239|Firmicutes	1239|Firmicutes	G	PTS system, Lactose Cellobiose specific IIA subunit	gmuA_1	-	2.7.1.196,2.7.1.205	ko:K02759	ko00500,ko02060,map00500,map02060	M00275	R11170,R11172	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.3.2	-	-	PTS_IIA
PKFBPKFJ_02902	1121115.AXVN01000102_gene3583	0.0	1006.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3Y00Y@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.86	ko:K01223	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT1	-	Glyco_hydro_1
PKFBPKFJ_02903	1121115.AXVN01000105_gene596	1.4e-57	178.0	2AD7W@1|root,312WU@2|Bacteria,1V7M4@1239|Firmicutes,24M52@186801|Clostridia,3Y0DD@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02904	1121115.AXVN01000105_gene597	1.43e-153	432.0	COG0745@1|root,COG0745@2|Bacteria,1TRK5@1239|Firmicutes,25B21@186801|Clostridia,3XZEA@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_02905	1121115.AXVN01000105_gene598	1.86e-216	598.0	COG0642@1|root,COG2205@2|Bacteria,1TPK5@1239|Firmicutes,247J0@186801|Clostridia,3XZSD@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_02906	1121115.AXVN01000105_gene599	6.04e-219	604.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,3XZCK@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_02907	1121115.AXVN01000105_gene600	1.78e-150	425.0	COG1277@1|root,3242W@2|Bacteria,1TV0K@1239|Firmicutes,25D6F@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02908	1121115.AXVN01000105_gene601	2.95e-92	270.0	COG1595@1|root,COG1595@2|Bacteria,1V0IC@1239|Firmicutes,25DT2@186801|Clostridia,3Y280@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
PKFBPKFJ_02909	411471.SUBVAR_04366	2.13e-311	851.0	COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,24AAW@186801|Clostridia,3WHDR@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_02910	457412.RSAG_01603	3.65e-158	444.0	COG0745@1|root,COG0745@2|Bacteria,1TYPK@1239|Firmicutes,247Y9@186801|Clostridia,3WJ41@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_02911	1121115.AXVN01000192_gene2633	0.0	946.0	COG3039@1|root,COG3039@2|Bacteria,1U377@1239|Firmicutes,24ASA@186801|Clostridia,3Y1AH@572511|Blautia	186801|Clostridia	L	COG NOG25267 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
PKFBPKFJ_02912	1121115.AXVN01000179_gene2886	1.38e-177	495.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,3Y1EC@572511|Blautia	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K20459	ko02010,map02010	M00254,M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
PKFBPKFJ_02913	1121115.AXVN01000179_gene2887	2.94e-152	430.0	COG4200@1|root,COG4200@2|Bacteria,1TP4G@1239|Firmicutes,249XU@186801|Clostridia,3Y26T@572511|Blautia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K20460	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
PKFBPKFJ_02914	411471.SUBVAR_04370	3.08e-165	464.0	COG4200@1|root,COG4200@2|Bacteria,1TRGZ@1239|Firmicutes,2498Y@186801|Clostridia,3WNQP@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K20461	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
PKFBPKFJ_02915	457412.RSAG_04533	1.59e-46	151.0	2E96C@1|root,333EY@2|Bacteria,1VEKX@1239|Firmicutes,24SUX@186801|Clostridia,3WPUV@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02916	1121115.AXVN01000210_gene191	3.04e-105	304.0	2B7W8@1|root,32135@2|Bacteria,1VT3T@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02917	411459.RUMOBE_01791	7.07e-195	548.0	COG2801@1|root,COG2801@2|Bacteria,1TQQY@1239|Firmicutes,2487W@186801|Clostridia,3Y2AA@572511|Blautia	186801|Clostridia	L	COG COG2801 Transposase and inactivated derivatives	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_2
PKFBPKFJ_02918	397287.C807_01799	1.26e-08	50.8	2BEY0@1|root,328PP@2|Bacteria,1UUMP@1239|Firmicutes,25766@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02919	97139.C824_05615	7.03e-57	185.0	COG0789@1|root,COG0789@2|Bacteria,1UZ91@1239|Firmicutes,24UAS@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648,MerR_1
PKFBPKFJ_02920	1121115.AXVN01000065_gene683	4.47e-177	493.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,24B9T@186801|Clostridia,3Y031@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_02921	97139.C824_05617	5.31e-95	298.0	291RB@1|root,2ZPBC@2|Bacteria,1W542@1239|Firmicutes,24W9E@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02922	457412.RSAG_01488	3.84e-121	346.0	COG1396@1|root,COG1396@2|Bacteria,1UZN9@1239|Firmicutes,24APP@186801|Clostridia,3WPRU@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_02923	457412.RSAG_01487	1.15e-39	131.0	2E5UB@1|root,330IM@2|Bacteria,1VI5J@1239|Firmicutes,24RAY@186801|Clostridia,3WRWI@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
PKFBPKFJ_02924	457412.RSAG_01486	5.43e-255	699.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WHJS@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_02925	457412.RSAG_01485	2.93e-260	713.0	COG3598@1|root,COG3598@2|Bacteria,1UIBK@1239|Firmicutes,24K1Q@186801|Clostridia,3WGEM@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol
PKFBPKFJ_02926	457412.RSAG_01484	5.16e-50	158.0	2CIZU@1|root,3323B@2|Bacteria,1VF1D@1239|Firmicutes,24QPV@186801|Clostridia,3WM82@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02927	457412.RSAG_01483	2.83e-52	164.0	2DQEK@1|root,32UNY@2|Bacteria,1VCGS@1239|Firmicutes,24MR4@186801|Clostridia,3WMND@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF5348)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
PKFBPKFJ_02928	457412.RSAG_01482	2.17e-304	834.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,3WHRE@541000|Ruminococcaceae	186801|Clostridia	M	plasmid recombination	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PKFBPKFJ_02929	457412.RSAG_01481	6.46e-83	245.0	2C5R4@1|root,32R5C@2|Bacteria,1V57Y@1239|Firmicutes,24HAA@186801|Clostridia,3WM4P@541000|Ruminococcaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PKFBPKFJ_02930	457412.RSAG_01480	4.78e-50	158.0	COG0863@1|root,COG0863@2|Bacteria,1TPR7@1239|Firmicutes,24A3P@186801|Clostridia	186801|Clostridia	L	Belongs to the N(4) N(6)-methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase
PKFBPKFJ_02931	457412.RSAG_01479	9.47e-43	139.0	COG3655@1|root,COG3655@2|Bacteria,1VEM0@1239|Firmicutes,24QPN@186801|Clostridia,3WKPK@541000|Ruminococcaceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
PKFBPKFJ_02932	457412.RSAG_01478	0.0	1284.0	COG0338@1|root,COG3392@1|root,COG0338@2|Bacteria,COG3392@2|Bacteria,1TRDX@1239|Firmicutes,25E75@186801|Clostridia,3WGR2@541000|Ruminococcaceae	186801|Clostridia	H	Site-specific DNA-methyltransferase (Adenine-specific)	dam	-	2.1.1.72	ko:K06223	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	-	-	-	MethyltransfD12
PKFBPKFJ_02933	457412.RSAG_01477	0.0	1207.0	COG1578@1|root,COG1578@2|Bacteria,1UMEP@1239|Firmicutes,24CV3@186801|Clostridia,3WI3I@541000|Ruminococcaceae	186801|Clostridia	L	AlwI restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_AlwI
PKFBPKFJ_02934	457412.RSAG_04527	6.53e-317	873.0	COG1846@1|root,COG1846@2|Bacteria,1VSDY@1239|Firmicutes,24YPA@186801|Clostridia,3WNYY@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02935	742733.HMPREF9469_03044	2.48e-233	656.0	COG3039@1|root,COG3039@2|Bacteria,1TQF8@1239|Firmicutes,24AUQ@186801|Clostridia,220CA@1506553|Lachnoclostridium	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02936	457412.RSAG_04527	1.74e-118	359.0	COG1846@1|root,COG1846@2|Bacteria,1VSDY@1239|Firmicutes,24YPA@186801|Clostridia,3WNYY@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02937	457412.RSAG_01475	3.25e-64	196.0	2C5R4@1|root,30J7R@2|Bacteria,1TTNT@1239|Firmicutes,24Q7C@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PKFBPKFJ_02938	457412.RSAG_01474	4.55e-76	227.0	2EQJM@1|root,33I5N@2|Bacteria,1VPBW@1239|Firmicutes,24WG5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02939	457412.RSAG_01473	2.72e-78	233.0	COG5658@1|root,COG5658@2|Bacteria,1VFT9@1239|Firmicutes	1239|Firmicutes	S	SdpI/YhfL protein family	-	-	-	-	-	-	-	-	-	-	-	-	SdpI
PKFBPKFJ_02940	1121115.AXVN01000065_gene680	1.07e-35	121.0	2CHQ1@1|root,3240C@2|Bacteria,1UQE2@1239|Firmicutes,25855@186801|Clostridia,3Y1Z3@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02941	1121115.AXVN01000008_gene2664	5.63e-106	310.0	COG2819@1|root,COG2819@2|Bacteria,1V1TT@1239|Firmicutes,24GDE@186801|Clostridia,3Y0P9@572511|Blautia	186801|Clostridia	S	hydrolase of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
PKFBPKFJ_02942	585394.RHOM_14875	2.67e-29	105.0	2CDFN@1|root,33CYY@2|Bacteria,1VEJK@1239|Firmicutes,24RI3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02943	1121115.AXVN01000045_gene2059	8.32e-85	273.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg
PKFBPKFJ_02944	457412.RSAG_00853	6.82e-30	117.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WN7G@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg
PKFBPKFJ_02945	411459.RUMOBE_02567	0.0	871.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,3Y0HN@572511|Blautia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,HD_5,Response_reg,Rrf2
PKFBPKFJ_02948	457412.RSAG_00888	4.45e-71	221.0	COG0716@1|root,COG1145@1|root,COG0716@2|Bacteria,COG1145@2|Bacteria,1VSX9@1239|Firmicutes,24ZRM@186801|Clostridia,3WSJJ@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Flavodoxin_5
PKFBPKFJ_02949	397291.C804_00209	1.07e-157	452.0	COG0258@1|root,COG0258@2|Bacteria,1UYXU@1239|Firmicutes,248E2@186801|Clostridia,27RU4@186928|unclassified Lachnospiraceae	186801|Clostridia	L	5'-3' exonuclease, N-terminal resolvase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
PKFBPKFJ_02950	457412.RSAG_00901	5.25e-149	419.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia,3WJ1H@541000|Ruminococcaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
PKFBPKFJ_02952	1121115.AXVN01000004_gene1939	8.87e-162	453.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,3XZ4H@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_02953	457412.RSAG_00367	0.0	1002.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3WSQQ@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PKFBPKFJ_02958	1033733.CAEK01000007_gene1628	4.28e-19	83.6	2DNRS@1|root,32YU9@2|Bacteria,1VI43@1239|Firmicutes,24QZ2@186801|Clostridia,22IKV@1570339|Peptoniphilaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02969	457412.RSAG_03209	9.39e-192	533.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,3WIE9@541000|Ruminococcaceae	186801|Clostridia	D	Stage II sporulation protein D	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
PKFBPKFJ_02970	1121115.AXVN01000115_gene2457	7.73e-201	557.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia,3Y09E@572511|Blautia	186801|Clostridia	M	COG COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
PKFBPKFJ_02971	457412.RSAG_03207	8.74e-235	646.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3WHIU@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	scrR	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
PKFBPKFJ_02972	1121115.AXVN01000115_gene2455	0.0	1217.0	COG1263@1|root,COG1264@1|root,COG2190@1|root,COG1263@2|Bacteria,COG1264@2|Bacteria,COG2190@2|Bacteria,1TP5X@1239|Firmicutes,247WT@186801|Clostridia,3XZ3A@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	2.7.1.211	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	M00269	R00811	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.1.2.1,4.A.1.2.10,4.A.1.2.12,4.A.1.2.9	-	-	PTS_EIIA_1,PTS_EIIB,PTS_EIIC
PKFBPKFJ_02973	1121115.AXVN01000115_gene2454	0.0	999.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3XZ5W@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	scrB	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
PKFBPKFJ_02974	1121115.AXVN01000115_gene2453	5.28e-53	166.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,3Y0F0@572511|Blautia	186801|Clostridia	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
PKFBPKFJ_02975	457412.RSAG_03203	3.78e-182	512.0	COG5263@1|root,COG5263@2|Bacteria,1UJWN@1239|Firmicutes,25FCE@186801|Clostridia,3WKY6@541000|Ruminococcaceae	186801|Clostridia	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1
PKFBPKFJ_02976	1121115.AXVN01000115_gene2450	3.1e-154	433.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,3XYGI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
PKFBPKFJ_02977	457412.RSAG_03201	5.46e-188	522.0	COG1192@1|root,COG1192@2|Bacteria,1UPGE@1239|Firmicutes,24A5R@186801|Clostridia,3WPYK@541000|Ruminococcaceae	186801|Clostridia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,HTH_3
PKFBPKFJ_02978	1121115.AXVN01000031_gene322	1.24e-31	110.0	2CA4Q@1|root,349NE@2|Bacteria,1VYK2@1239|Firmicutes,253VZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_02979	1121115.AXVN01000031_gene323	2.33e-237	653.0	COG1609@1|root,COG1609@2|Bacteria,1TPZM@1239|Firmicutes,248WQ@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
PKFBPKFJ_02980	1121115.AXVN01000031_gene324	3.96e-293	801.0	COG2182@1|root,COG2182@2|Bacteria,1TPU9@1239|Firmicutes,249BY@186801|Clostridia,3Y07A@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K15770	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	SBP_bac_8
PKFBPKFJ_02981	1121115.AXVN01000031_gene325	0.0	931.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia,3XZSU@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K15771	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
PKFBPKFJ_02982	1121115.AXVN01000031_gene326	8.7e-196	543.0	COG3833@1|root,COG3833@2|Bacteria,1TRB7@1239|Firmicutes,248A7@186801|Clostridia,3XZSX@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K15772	ko02010,map02010	M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
PKFBPKFJ_02983	1121115.AXVN01000031_gene327	2.13e-183	510.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,3Y013@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
PKFBPKFJ_02984	411461.DORFOR_01832	4.54e-150	422.0	COG2452@1|root,COG2452@2|Bacteria,1UZ1U@1239|Firmicutes,24F52@186801|Clostridia	186801|Clostridia	L	SMART HTH transcriptional regulator, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1,Resolvase
PKFBPKFJ_02985	411461.DORFOR_01831	6.1e-276	754.0	COG0675@1|root,COG0675@2|Bacteria,1TRNY@1239|Firmicutes,247T1@186801|Clostridia,27WYV@189330|Dorea	186801|Clostridia	L	COG COG0675 Transposase and inactivated derivatives	-	-	-	ko:K07496	-	-	-	-	ko00000	-	-	-	HTH_OrfB_IS605,OrfB_IS605,OrfB_Zn_ribbon
PKFBPKFJ_02986	1121115.AXVN01000031_gene330	0.0	1405.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3XYX5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pbg	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
PKFBPKFJ_02987	457412.RSAG_03197	0.0	2225.0	COG0553@1|root,COG4715@1|root,COG0553@2|Bacteria,COG4715@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3WGFC@541000|Ruminococcaceae	186801|Clostridia	KL	SNF2 family	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
PKFBPKFJ_02988	1121115.AXVN01000031_gene332	7.11e-124	353.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,3XZW9@572511|Blautia	186801|Clostridia	K	COG COG2002 Regulators of stationary sporulation gene expression	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
PKFBPKFJ_02989	1121115.AXVN01000031_gene333	8.19e-294	801.0	COG1408@1|root,COG1408@2|Bacteria,1TS43@1239|Firmicutes,248XA@186801|Clostridia,3XZND@572511|Blautia	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
PKFBPKFJ_02990	1121115.AXVN01000031_gene334	0.0	956.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,3XZKK@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
PKFBPKFJ_02992	1121115.AXVN01000031_gene335	3.39e-132	374.0	COG1595@1|root,COG1595@2|Bacteria,1V1JW@1239|Firmicutes,24FYN@186801|Clostridia,3Y0F3@572511|Blautia	186801|Clostridia	K	DNA-directed RNA polymerase sigma subunit (RpoE,sigma24)	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_02993	1121115.AXVN01000031_gene336	3.12e-292	798.0	29WCT@1|root,30HYG@2|Bacteria,1TYPB@1239|Firmicutes,258RC@186801|Clostridia,3Y1W1@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
PKFBPKFJ_02994	397291.C804_00692	2.31e-45	160.0	COG0582@1|root,COG0582@2|Bacteria,1UXHG@1239|Firmicutes,25ME8@186801|Clostridia,27SHE@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PKFBPKFJ_02995	1121115.AXVN01000031_gene338	1.11e-240	664.0	COG5464@1|root,COG5464@2|Bacteria,1VVMJ@1239|Firmicutes,250U7@186801|Clostridia,3Y23T@572511|Blautia	2|Bacteria	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
PKFBPKFJ_02996	1121115.AXVN01000031_gene339	0.0	892.0	COG2942@1|root,COG2942@2|Bacteria,1UQC2@1239|Firmicutes,24D2T@186801|Clostridia,3Y1CF@572511|Blautia	186801|Clostridia	G	N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)	-	-	-	-	-	-	-	-	-	-	-	-	GlcNAc_2-epim
PKFBPKFJ_02997	1121115.AXVN01000031_gene340	3.76e-70	212.0	COG1115@1|root,COG1115@2|Bacteria,1VUZR@1239|Firmicutes,25092@186801|Clostridia	186801|Clostridia	E	Sodium:alanine symporter family	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ala_symp
PKFBPKFJ_02998	457412.RSAG_03191	4.16e-150	422.0	COG0461@1|root,COG0461@2|Bacteria,1V23H@1239|Firmicutes,24FTS@186801|Clostridia,3WIVV@541000|Ruminococcaceae	186801|Clostridia	F	Orotate phosphoribosyltransferase	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
PKFBPKFJ_02999	1121115.AXVN01000031_gene342	8.64e-162	454.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3XYV6@572511|Blautia	186801|Clostridia	T	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP_1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03000	1121115.AXVN01000031_gene343	0.0	1462.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia,3XYZD@572511|Blautia	186801|Clostridia	T	COG COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_03001	1121115.AXVN01000031_gene344	3.3e-176	490.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia,3XZPR@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
PKFBPKFJ_03002	1121115.AXVN01000031_gene345	8.52e-208	573.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia,3XZSF@572511|Blautia	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
PKFBPKFJ_03003	1121115.AXVN01000031_gene346	9.87e-175	486.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,3XYMH@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
PKFBPKFJ_03004	1121115.AXVN01000031_gene348	8.09e-195	540.0	COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,24D7F@186801|Clostridia,3XYMP@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
PKFBPKFJ_03005	1121115.AXVN01000031_gene349	2.81e-194	539.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,3XZD5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
PKFBPKFJ_03006	457412.RSAG_03182	0.0	2281.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3WGNQ@541000|Ruminococcaceae	186801|Clostridia	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
PKFBPKFJ_03007	457412.RSAG_03181	1.65e-240	660.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3WH67@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
PKFBPKFJ_03008	457412.RSAG_03180	0.0	892.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3WGPB@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
PKFBPKFJ_03009	1121115.AXVN01000031_gene353	5.03e-148	417.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,3XZZU@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
PKFBPKFJ_03010	1121115.AXVN01000031_gene354	1.05e-178	498.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,3XYZF@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
PKFBPKFJ_03011	1121115.AXVN01000055_gene1900	4.78e-90	265.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,3Y0IA@572511|Blautia	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
PKFBPKFJ_03012	1121115.AXVN01000055_gene1901	1.41e-151	434.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3XZEQ@572511|Blautia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
PKFBPKFJ_03013	1121115.AXVN01000055_gene1902	1.66e-245	673.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3XYMZ@572511|Blautia	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
PKFBPKFJ_03014	457412.RSAG_03174	4.33e-192	533.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3WHDB@541000|Ruminococcaceae	186801|Clostridia	HK	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
PKFBPKFJ_03015	1121115.AXVN01000055_gene1904	2.46e-81	241.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia,3Y06J@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03016	457412.RSAG_03172	1.03e-240	661.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,3WGDN@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
PKFBPKFJ_03017	1121115.AXVN01000055_gene1906	1.94e-99	290.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,3XZTG@572511|Blautia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
PKFBPKFJ_03018	457412.RSAG_03170	0.0	1274.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,3WH32@541000|Ruminococcaceae	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
PKFBPKFJ_03019	1280698.AUJS01000020_gene1386	1.23e-48	155.0	2EBZC@1|root,335YN@2|Bacteria,1V8B8@1239|Firmicutes,24TTD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03020	471875.RUMLAC_00018	1.47e-45	147.0	28N4M@1|root,2ZBA1@2|Bacteria,1V0M7@1239|Firmicutes,24FM3@186801|Clostridia,3WM4X@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348,Tn916-Xis
PKFBPKFJ_03021	1280698.AUJS01000020_gene1388	1.4e-75	227.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,24GMD@186801|Clostridia,27VRF@189330|Dorea	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PKFBPKFJ_03022	1280698.AUJS01000020_gene1389	1.11e-35	120.0	2FGU8@1|root,348PJ@2|Bacteria,1W0KZ@1239|Firmicutes,24QZ0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03023	428125.CLOLEP_03440	6.62e-163	458.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,3WG7Z@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03024	428125.CLOLEP_03439	0.0	1045.0	COG0577@1|root,COG0577@2|Bacteria,1TSIZ@1239|Firmicutes,2491R@186801|Clostridia,3WRSM@541000|Ruminococcaceae	186801|Clostridia	V	COG COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
PKFBPKFJ_03025	428125.CLOLEP_03438	8.4e-133	380.0	COG0745@1|root,COG0745@2|Bacteria,1UYQ0@1239|Firmicutes,24DUM@186801|Clostridia	186801|Clostridia	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03026	428125.CLOLEP_03437	1.79e-221	613.0	COG0642@1|root,COG0642@2|Bacteria,1UI63@1239|Firmicutes,25FS2@186801|Clostridia	186801|Clostridia	T	COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
PKFBPKFJ_03027	428125.CLOLEP_00341	2.71e-97	285.0	2DUIS@1|root,33QVG@2|Bacteria,1VQUS@1239|Firmicutes,25E0I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03028	1506994.JNLQ01000005_gene3978	1.13e-67	229.0	COG1002@1|root,COG1002@2|Bacteria,1TRZH@1239|Firmicutes,249I6@186801|Clostridia,4C0Z2@830|Butyrivibrio	186801|Clostridia	V	Type II restriction enzyme, methylase subunits	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
PKFBPKFJ_03029	518637.EUBIFOR_00788	6.96e-86	253.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes	1239|Firmicutes	L	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism	ssb1	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
PKFBPKFJ_03030	1280698.AUJS01000020_gene1399	2.02e-39	130.0	COG3655@1|root,COG3655@2|Bacteria,1VA6A@1239|Firmicutes	1239|Firmicutes	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
PKFBPKFJ_03031	518637.EUBIFOR_00775	3.18e-61	192.0	2F3XK@1|root,33WPP@2|Bacteria,1VWC7@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3847)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
PKFBPKFJ_03032	1280698.AUJS01000020_gene1401	0.0	1048.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PKFBPKFJ_03033	1280698.AUJS01000020_gene1402	0.0	1174.0	COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1TQKP@1239|Firmicutes,247WJ@186801|Clostridia,27VNS@189330|Dorea	186801|Clostridia	L	COG NOG14428 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,DUF3991,Toprim_2
PKFBPKFJ_03034	471875.RUMLAC_00026	2.99e-49	156.0	2E9Z3@1|root,3344K@2|Bacteria,1VAAS@1239|Firmicutes,24NEW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03035	471875.RUMLAC_00025	4.95e-86	253.0	2DM2C@1|root,31EMM@2|Bacteria,1V8MD@1239|Firmicutes,24JEA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03036	1280698.AUJS01000020_gene1405	1.5e-40	134.0	2E3CH@1|root,32YBT@2|Bacteria,1VHJT@1239|Firmicutes,24RED@186801|Clostridia,27X7K@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03037	1280698.AUJS01000020_gene1406	2.53e-31	109.0	2E7G7@1|root,339KC@2|Bacteria,1VNP0@1239|Firmicutes,24WCK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03038	1280698.AUJS01000020_gene1407	9.53e-305	830.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,27W4D@189330|Dorea	186801|Clostridia	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_int_SAM_4,Phage_int_SAM_5,Phage_integrase
PKFBPKFJ_03039	1121115.AXVN01000055_gene1907	2.3e-93	291.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,3XZC3@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
PKFBPKFJ_03040	457412.RSAG_03169	0.0	1035.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,3WJCS@541000|Ruminococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
PKFBPKFJ_03041	1121115.AXVN01000055_gene1909	2.54e-242	665.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3XZ1P@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
PKFBPKFJ_03042	1121115.AXVN01000055_gene1910	1.38e-220	608.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3Y14P@572511|Blautia	186801|Clostridia	E	Oligopeptide/dipeptide transporter, C-terminal region	oppF	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
PKFBPKFJ_03043	1121115.AXVN01000055_gene1911	1.77e-236	650.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZP5@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
PKFBPKFJ_03044	1121115.AXVN01000055_gene1912	4.17e-204	565.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZFZ@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
PKFBPKFJ_03045	1121115.AXVN01000055_gene1913	0.0	1112.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
PKFBPKFJ_03046	1121115.AXVN01000055_gene1914	2.57e-52	164.0	2CDIT@1|root,338T3@2|Bacteria,1VJ1M@1239|Firmicutes,24SF4@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1292)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
PKFBPKFJ_03047	1121115.AXVN01000055_gene1915	1.52e-264	725.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,3XYVJ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7,Fer4_9
PKFBPKFJ_03048	1121115.AXVN01000055_gene1916	3.45e-240	659.0	COG5018@1|root,COG5018@2|Bacteria,1TQJZ@1239|Firmicutes,24845@186801|Clostridia,3XYID@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
PKFBPKFJ_03049	457412.RSAG_03160	5.43e-295	805.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3WJ4Y@541000|Ruminococcaceae	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
PKFBPKFJ_03050	457412.RSAG_03158	0.0	2164.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3WG9B@541000|Ruminococcaceae	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1,zf-FPG_IleRS
PKFBPKFJ_03051	1121115.AXVN01000055_gene1920	0.0	1638.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3XZEY@572511|Blautia	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
PKFBPKFJ_03052	1121115.AXVN01000055_gene1921	2.38e-108	311.0	2BFEN@1|root,32988@2|Bacteria,1UQ3F@1239|Firmicutes,257RJ@186801|Clostridia,3Y0RW@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4869)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4869
PKFBPKFJ_03053	1121115.AXVN01000055_gene1922	1.31e-140	397.0	28I6P@1|root,2Z89K@2|Bacteria,1TSZ7@1239|Firmicutes,24AUY@186801|Clostridia,3Y0II@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03054	1121115.AXVN01000166_gene698	0.0	2222.0	COG3209@1|root,COG3209@2|Bacteria,1VBDM@1239|Firmicutes	1239|Firmicutes	M	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,Cohesin
PKFBPKFJ_03055	1121115.AXVN01000172_gene3991	5.41e-293	800.0	COG2865@1|root,COG2865@2|Bacteria,1TSPK@1239|Firmicutes,24B9Q@186801|Clostridia,3XZHR@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AlbA_2,HATPase_c_4
PKFBPKFJ_03056	457412.RSAG_04544	8.29e-93	312.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CAP,G5,SLH,fn3
PKFBPKFJ_03057	411469.EUBHAL_01615	1.9e-163	465.0	COG5464@1|root,COG5464@2|Bacteria,1TS6U@1239|Firmicutes,24A2X@186801|Clostridia,25WK9@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
PKFBPKFJ_03058	1121115.AXVN01000137_gene1817	1.53e-149	419.0	COG5279@1|root,COG5279@2|Bacteria,1V2RG@1239|Firmicutes,24GD8@186801|Clostridia	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PKFBPKFJ_03059	1121115.AXVN01000137_gene1818	5.91e-40	132.0	COG1672@1|root,COG1672@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PKFBPKFJ_03060	658088.HMPREF0987_00515	1.62e-52	170.0	29AZ1@1|root,2ZXY1@2|Bacteria,1V4KY@1239|Firmicutes,24I9C@186801|Clostridia,27Q6H@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03061	1121115.AXVN01000137_gene1820	6.21e-172	479.0	29XPW@1|root,30JFI@2|Bacteria,1TTS7@1239|Firmicutes,257QZ@186801|Clostridia,3Y1YX@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3990
PKFBPKFJ_03062	457412.RSAG_03139	0.0	1477.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria,1UK8D@1239|Firmicutes,25FQD@186801|Clostridia,3WJ22@541000|Ruminococcaceae	186801|Clostridia	N	cellulase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03063	457412.RSAG_03138	9.8e-199	551.0	COG1047@1|root,COG1433@1|root,COG1047@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,24BUF@186801|Clostridia	186801|Clostridia	O	dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	FKBP_C,Nitro_FeMo-Co
PKFBPKFJ_03064	457412.RSAG_03137	4.82e-228	628.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,3WITB@541000|Ruminococcaceae	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	lytC_3	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
PKFBPKFJ_03065	457412.RSAG_04544	4.73e-32	130.0	COG2340@1|root,COG2340@2|Bacteria	2|Bacteria	S	peptidase inhibitor activity	-	-	3.4.24.40	ko:K01406	ko01503,map01503	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CAP,G5,SLH,fn3
PKFBPKFJ_03066	457412.RSAG_03136	2.37e-226	625.0	COG5464@1|root,COG5464@2|Bacteria,1TYQI@1239|Firmicutes,24FIE@186801|Clostridia,3WRZY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
PKFBPKFJ_03067	1121115.AXVN01000091_gene2614	2.01e-278	766.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia,3Y0NN@572511|Blautia	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_03068	457412.RSAG_03133	2.79e-174	486.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,3WI78@541000|Ruminococcaceae	186801|Clostridia	I	Phosphate acyltransferases	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
PKFBPKFJ_03069	1121115.AXVN01000091_gene2612	3.16e-93	272.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia,3Y0BV@572511|Blautia	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
PKFBPKFJ_03070	457412.RSAG_03131	0.0	998.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,3WHGK@541000|Ruminococcaceae	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
PKFBPKFJ_03071	1121115.AXVN01000091_gene2610	1.15e-204	566.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3XZ86@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
PKFBPKFJ_03072	1121115.AXVN01000091_gene2609	4.75e-157	442.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,3XZAU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	GntR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
PKFBPKFJ_03073	1121115.AXVN01000091_gene2608	0.0	954.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,3XZAJ@572511|Blautia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	gerA	-	-	ko:K06310	-	-	-	-	ko00000	-	-	-	GerA
PKFBPKFJ_03074	1121115.AXVN01000091_gene2607	0.0	1099.0	COG0814@1|root,COG0814@2|Bacteria,1V9NE@1239|Firmicutes,25FHY@186801|Clostridia,3XZUD@572511|Blautia	186801|Clostridia	E	Spore germination protein	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
PKFBPKFJ_03075	1121115.AXVN01000091_gene2606	6.51e-54	169.0	2C5NI@1|root,33W5Y@2|Bacteria,1VWK5@1239|Firmicutes,2519Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03076	1121115.AXVN01000091_gene2605	2.61e-196	544.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,3XZR8@572511|Blautia	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
PKFBPKFJ_03077	1121115.AXVN01000091_gene2604	5.7e-105	303.0	COG4506@1|root,COG4506@2|Bacteria,1V8CS@1239|Firmicutes,24JQR@186801|Clostridia,3Y0D5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
PKFBPKFJ_03078	1121115.AXVN01000091_gene2603	7.73e-72	219.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia,3Y02Y@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03079	457412.RSAG_03122	0.0	1003.0	COG0726@1|root,COG0726@2|Bacteria,1TWQ0@1239|Firmicutes,24BEF@186801|Clostridia,3WI2D@541000|Ruminococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
PKFBPKFJ_03080	457412.RSAG_03121	0.0	911.0	COG0726@1|root,COG0726@2|Bacteria,1TWQ0@1239|Firmicutes,24BEF@186801|Clostridia,3WI2D@541000|Ruminococcaceae	186801|Clostridia	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
PKFBPKFJ_03081	1121115.AXVN01000076_gene2630	4.38e-272	748.0	COG0544@1|root,COG0544@2|Bacteria,1V3TE@1239|Firmicutes,24AAA@186801|Clostridia,3Y00S@572511|Blautia	186801|Clostridia	M	COG COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	tig_1	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C
PKFBPKFJ_03082	457412.RSAG_03119	6.55e-270	745.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24MJ1@186801|Clostridia,3WRJS@541000|Ruminococcaceae	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Big_2,CW_binding_1,Cu_amine_oxidN1,DUF3298,Polysacc_deac_1,SH3_3
PKFBPKFJ_03083	457412.RSAG_03118	0.0	1320.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3WGDM@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
PKFBPKFJ_03084	1121115.AXVN01000076_gene2627	6.5e-48	153.0	2E6AD@1|root,330Y9@2|Bacteria,1VFG8@1239|Firmicutes,24RI6@186801|Clostridia,3Y0I9@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03085	1121115.AXVN01000076_gene2625	3.75e-214	599.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,3XYNY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
PKFBPKFJ_03086	457412.RSAG_03114	9.1e-235	645.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia,3WGKW@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	cobW
PKFBPKFJ_03087	1121115.AXVN01000076_gene2623	1.32e-138	391.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3XYSI@572511|Blautia	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
PKFBPKFJ_03088	457412.RSAG_03112	0.0	2158.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3WGVW@541000|Ruminococcaceae	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
PKFBPKFJ_03089	1121115.AXVN01000076_gene2621	2.93e-260	718.0	COG0760@1|root,COG0760@2|Bacteria,1V1WU@1239|Firmicutes,24G3V@186801|Clostridia,3Y03A@572511|Blautia	186801|Clostridia	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
PKFBPKFJ_03090	1121115.AXVN01000076_gene2620	5.08e-195	540.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia,3Y059@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
PKFBPKFJ_03091	1121115.AXVN01000076_gene2619	4.24e-290	791.0	28HI8@1|root,2Z7TS@2|Bacteria,1TQTK@1239|Firmicutes,249WK@186801|Clostridia,3XZQQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
PKFBPKFJ_03092	1121115.AXVN01000076_gene2618	1.85e-121	346.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,3Y0KM@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	nfrA2	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
PKFBPKFJ_03093	1121115.AXVN01000076_gene2617	2.59e-96	280.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,3Y0J7@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
PKFBPKFJ_03094	698769.JFBD01000024_gene1884	2.65e-84	253.0	arCOG05874@1|root,2ZJ01@2|Bacteria,1V450@1239|Firmicutes,4HFPA@91061|Bacilli,4C6TS@84406|Virgibacillus	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03099	1121115.AXVN01000185_gene1766	8.48e-284	776.0	COG0582@1|root,COG0582@2|Bacteria,1VRYY@1239|Firmicutes,24XX1@186801|Clostridia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PKFBPKFJ_03100	411470.RUMGNA_01373	2.01e-275	754.0	2C5T8@1|root,2Z910@2|Bacteria,1TQ5T@1239|Firmicutes,24BDG@186801|Clostridia,3XZQ6@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03101	1121115.AXVN01000138_gene1661	1.61e-249	684.0	COG5377@1|root,COG5377@2|Bacteria,1TS2Y@1239|Firmicutes,249SB@186801|Clostridia,3XZRF@572511|Blautia	186801|Clostridia	L	YqaJ-like viral recombinase domain	-	-	-	-	-	-	-	-	-	-	-	-	YqaJ
PKFBPKFJ_03102	742765.HMPREF9457_03397	2.65e-93	272.0	2CGYE@1|root,32TDD@2|Bacteria,1VDFY@1239|Firmicutes,24PCD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03103	1121115.AXVN01000138_gene1659	0.0	1411.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,248P4@186801|Clostridia,3XYZM@572511|Blautia	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
PKFBPKFJ_03104	411470.RUMGNA_01377	9.5e-214	592.0	28M0I@1|root,2ZAFJ@2|Bacteria,1UYB4@1239|Firmicutes,24B6X@186801|Clostridia,3XYYZ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03105	742765.HMPREF9457_03400	2.9e-296	807.0	COG0358@1|root,COG0358@2|Bacteria,1UYVG@1239|Firmicutes,24GCV@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3854,YodL,zf-CHC2
PKFBPKFJ_03106	742765.HMPREF9457_03401	4.13e-183	509.0	COG4509@1|root,COG4509@2|Bacteria,1TRWN@1239|Firmicutes,24JWH@186801|Clostridia	186801|Clostridia	M	sortase, SrtB family	-	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
PKFBPKFJ_03107	742765.HMPREF9457_03402	4.33e-95	277.0	2EKZP@1|root,33EP5@2|Bacteria,1VNSF@1239|Firmicutes,24WAB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03108	1121115.AXVN01000033_gene2922	2.47e-222	612.0	COG0849@1|root,COG0849@2|Bacteria,1TQ6Z@1239|Firmicutes,25GFN@186801|Clostridia	186801|Clostridia	D	cell division	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	-
PKFBPKFJ_03109	1121115.AXVN01000033_gene2921	1.65e-76	229.0	2EC9H@1|root,3367V@2|Bacteria,1VK0Q@1239|Firmicutes,24RE7@186801|Clostridia,3Y0GJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03110	1121115.AXVN01000033_gene2920	3.33e-69	209.0	COG1396@1|root,COG1396@2|Bacteria,1UVHU@1239|Firmicutes,25KIK@186801|Clostridia,3Y0BF@572511|Blautia	186801|Clostridia	K	regulator of the anaerobic catobolism of benzoate BzdR K00891	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_03111	1121115.AXVN01000033_gene2919	1.26e-96	281.0	2BWHI@1|root,32VUW@2|Bacteria,1VA4V@1239|Firmicutes,24PD2@186801|Clostridia,3XZWI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
PKFBPKFJ_03112	1121115.AXVN01000033_gene2918	3.62e-38	127.0	2DKB1@1|root,3092I@2|Bacteria,1U4C3@1239|Firmicutes,25PCG@186801|Clostridia,3Y0I6@572511|Blautia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
PKFBPKFJ_03113	411470.RUMGNA_01391	1.01e-14	68.2	29V16@1|root,30GEA@2|Bacteria,1UFV4@1239|Firmicutes,25MT1@186801|Clostridia,3Y1Y9@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03114	742765.HMPREF9457_03410	6.5e-162	454.0	COG3279@1|root,COG3279@2|Bacteria	2|Bacteria	KT	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_03115	411470.RUMGNA_01393	3.74e-22	86.3	2BP0Y@1|root,32HRB@2|Bacteria,1UFZ1@1239|Firmicutes,25N19@186801|Clostridia,3Y20K@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03116	742765.HMPREF9457_03412	4.36e-241	664.0	COG0641@1|root,COG0641@2|Bacteria,1V7CW@1239|Firmicutes,24ZGK@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03117	411470.RUMGNA_01395	5.79e-54	172.0	29UMC@1|root,30FYU@2|Bacteria,1UEW8@1239|Firmicutes,25JVQ@186801|Clostridia,3Y1HQ@572511|Blautia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_03118	742765.HMPREF9457_03414	9.39e-167	466.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,27WT9@189330|Dorea	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_03119	742765.HMPREF9457_03415	2.54e-276	761.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,2494S@186801|Clostridia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,SPOB_a
PKFBPKFJ_03120	742765.HMPREF9457_03416	5.66e-189	526.0	2EIRY@1|root,33CHA@2|Bacteria,1VP9K@1239|Firmicutes,24WNX@186801|Clostridia	186801|Clostridia	S	Zinc dependent phospholipase C (alpha toxin)	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
PKFBPKFJ_03121	1121115.AXVN01000033_gene2912	4.22e-285	778.0	COG0641@1|root,COG0641@2|Bacteria,1W6UR@1239|Firmicutes,25M2Y@186801|Clostridia,3XYSP@572511|Blautia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM
PKFBPKFJ_03122	742765.HMPREF9457_03418	0.0	1002.0	COG1132@1|root,COG1132@2|Bacteria,1UYYQ@1239|Firmicutes,24BTI@186801|Clostridia	186801|Clostridia	V	abc transporter atp-binding protein	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PKFBPKFJ_03123	742765.HMPREF9457_03419	3.8e-210	583.0	COG1404@1|root,COG1404@2|Bacteria	2|Bacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8,SLH
PKFBPKFJ_03124	742765.HMPREF9457_03420	6.75e-233	644.0	COG0641@1|root,COG0641@2|Bacteria,1V5ZZ@1239|Firmicutes,24IY0@186801|Clostridia	186801|Clostridia	C	Radical SAM superfamily	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
PKFBPKFJ_03125	742765.HMPREF9457_03421	2.57e-249	690.0	COG0535@1|root,COG0535@2|Bacteria,1UKP0@1239|Firmicutes,25G28@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
PKFBPKFJ_03126	411470.RUMGNA_01404	4.9e-14	65.1	29U3X@1|root,30FDD@2|Bacteria,1UDW0@1239|Firmicutes,25IPU@186801|Clostridia,3Y21C@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score 8.82	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03127	478749.BRYFOR_06535	2.98e-142	403.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03128	1235835.C814_02690	0.0	1434.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,3WHE4@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
PKFBPKFJ_03132	658655.HMPREF0988_01967	0.0	1057.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,27MCJ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase domain (DUF772)	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
PKFBPKFJ_03133	397288.C806_04399	3.47e-41	147.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,249PK@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03134	411470.RUMGNA_01411	1.72e-62	193.0	COG1396@1|root,COG1396@2|Bacteria,1VC8I@1239|Firmicutes,24PQF@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_03135	1121115.AXVN01000005_gene2281	7.85e-241	662.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
PKFBPKFJ_03136	1121115.AXVN01000005_gene2280	6.9e-166	463.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,3XYM6@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
PKFBPKFJ_03137	457412.RSAG_02988	6.65e-181	503.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,3WK2R@541000|Ruminococcaceae	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
PKFBPKFJ_03138	1121115.AXVN01000005_gene2278	3.76e-141	400.0	COG1207@1|root,COG1207@2|Bacteria,1UH92@1239|Firmicutes,25PYU@186801|Clostridia,3XYPK@572511|Blautia	186801|Clostridia	M	UDP-N-acetylglucosamine diphosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
PKFBPKFJ_03139	1121115.AXVN01000005_gene2277	0.0	1382.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3XYKF@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	traI	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
PKFBPKFJ_03140	1121115.AXVN01000005_gene2276	2.21e-177	494.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,3XZWD@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	fnt	-	-	ko:K02598	-	-	-	-	ko00000,ko02000	1.A.16.3	-	-	Form_Nir_trans
PKFBPKFJ_03141	1121115.AXVN01000005_gene2275	3.09e-248	681.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,3XZ8H@572511|Blautia	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
PKFBPKFJ_03142	1121115.AXVN01000005_gene2274	8e-49	155.0	2DR4V@1|root,33A63@2|Bacteria,1VKGM@1239|Firmicutes,24UDH@186801|Clostridia,3Y0TN@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
PKFBPKFJ_03143	1121115.AXVN01000005_gene2273	1.58e-264	724.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3XZ7K@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
PKFBPKFJ_03144	1121115.AXVN01000005_gene2272	0.0	910.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,3XYGK@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
PKFBPKFJ_03145	457412.RSAG_02996	1.58e-151	425.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia,3WGWP@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
PKFBPKFJ_03146	1121115.AXVN01000005_gene2270	5.19e-223	614.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,248VU@186801|Clostridia,3XYYF@572511|Blautia	186801|Clostridia	I	Phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
PKFBPKFJ_03147	1121115.AXVN01000005_gene2269	3.98e-135	384.0	COG1183@1|root,COG1183@2|Bacteria,1TTB7@1239|Firmicutes,24GPU@186801|Clostridia,3XZVV@572511|Blautia	186801|Clostridia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
PKFBPKFJ_03148	457412.RSAG_02999	7.1e-155	440.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,3WHJD@541000|Ruminococcaceae	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
PKFBPKFJ_03149	1121115.AXVN01000107_gene618	9.07e-158	442.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,3XZPI@572511|Blautia	186801|Clostridia	T	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	cutR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03150	457412.RSAG_01693	4.73e-265	727.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,3WSRQ@541000|Ruminococcaceae	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	arlS	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
PKFBPKFJ_03151	1121115.AXVN01000107_gene616	2.49e-256	702.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,3XZ15@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
PKFBPKFJ_03152	457412.RSAG_01696	2.64e-98	285.0	COG3543@1|root,COG3543@2|Bacteria,1VAZC@1239|Firmicutes,25DS7@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1284)	-	-	-	ko:K09706	-	-	-	-	ko00000	-	-	-	DUF1284
PKFBPKFJ_03153	1121115.AXVN01000107_gene614	2.35e-205	569.0	COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,248I1@186801|Clostridia,3XYIR@572511|Blautia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	EamA
PKFBPKFJ_03154	1121115.AXVN01000107_gene613	7.86e-132	374.0	COG4732@1|root,COG4732@2|Bacteria,1V6HH@1239|Firmicutes,24JF7@186801|Clostridia,3Y0SC@572511|Blautia	186801|Clostridia	S	Thiamine-precursor transporter protein (ThiW)	thiW	-	-	-	-	-	-	-	-	-	-	-	ThiW
PKFBPKFJ_03155	1121115.AXVN01000107_gene612	1.11e-144	410.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,3XZZP@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
PKFBPKFJ_03156	1121115.AXVN01000107_gene611	0.0	869.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3XZ7Z@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_03157	457412.RSAG_01701	5.62e-316	861.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,3WGU0@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	Voltage_CLC
PKFBPKFJ_03158	1121115.AXVN01000107_gene609	0.0	1422.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
PKFBPKFJ_03159	457412.RSAG_03503	5.22e-227	625.0	COG3039@1|root,COG3039@2|Bacteria,1UZVA@1239|Firmicutes,24AU2@186801|Clostridia,3WN3Y@541000|Ruminococcaceae	186801|Clostridia	L	PFAM transposase IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_3
PKFBPKFJ_03160	397290.C810_03441	1.84e-81	259.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,27K85@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_03162	1121115.AXVN01000030_gene3637	4.57e-271	744.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3XZ8E@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	macB2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PKFBPKFJ_03163	457412.RSAG_03345	8.92e-288	803.0	COG0845@1|root,COG0845@2|Bacteria,1UZA4@1239|Firmicutes,24BV0@186801|Clostridia,3WJXH@541000|Ruminococcaceae	186801|Clostridia	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
PKFBPKFJ_03164	1121115.AXVN01000030_gene3639	4.29e-171	478.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3XYST@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03165	1121115.AXVN01000030_gene3640	0.0	897.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3XZF0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
PKFBPKFJ_03166	457412.RSAG_03342	0.0	1132.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia,3WHYM@541000|Ruminococcaceae	186801|Clostridia	S	Predicted ATPase of the ABC class	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
PKFBPKFJ_03167	97139.C824_02830	3.68e-117	352.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,36F0S@31979|Clostridiaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
PKFBPKFJ_03171	887325.HMPREF0381_1082	1.89e-51	167.0	2ET36@1|root,33KMC@2|Bacteria,1VKQN@1239|Firmicutes,24UID@186801|Clostridia,1HW30@1164882|Lachnoanaerobaculum	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HIRAN
PKFBPKFJ_03172	1519439.JPJG01000054_gene2127	4.08e-15	70.1	2BCKR@1|root,3266U@2|Bacteria,1US5H@1239|Firmicutes,25A4B@186801|Clostridia,2N8VG@216572|Oscillospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03174	457412.RSAG_02064	1.12e-24	99.0	COG5464@1|root,COG5464@2|Bacteria,1V2ZE@1239|Firmicutes,25DF2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
PKFBPKFJ_03175	1121115.AXVN01000133_gene741	5.8e-270	739.0	29WCT@1|root,30HYG@2|Bacteria,1TYPB@1239|Firmicutes,258RC@186801|Clostridia,3Y1W1@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
PKFBPKFJ_03176	1121115.AXVN01000133_gene740	2.19e-130	370.0	COG1595@1|root,COG1595@2|Bacteria,1V9GU@1239|Firmicutes,24KTH@186801|Clostridia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_03177	457412.RSAG_02064	4.46e-189	526.0	COG5464@1|root,COG5464@2|Bacteria,1V2ZE@1239|Firmicutes,25DF2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
PKFBPKFJ_03178	1121115.AXVN01000079_gene2733	0.0	927.0	COG0772@1|root,COG0772@2|Bacteria,1TRIP@1239|Firmicutes,258QF@186801|Clostridia,3Y1Z2@572511|Blautia	186801|Clostridia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03179	1121115.AXVN01000079_gene2734	1.14e-69	210.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,3Y1TV@572511|Blautia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
PKFBPKFJ_03180	1121115.AXVN01000079_gene2735	1.33e-227	625.0	COG0826@1|root,COG0826@2|Bacteria,1TRX5@1239|Firmicutes,24CTG@186801|Clostridia,3Y1A4@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03181	1121115.AXVN01000079_gene2736	1.57e-37	126.0	2C4UK@1|root,346TK@2|Bacteria,1W0FK@1239|Firmicutes,2530T@186801|Clostridia,3Y21U@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03182	1121115.AXVN01000079_gene2737	1.44e-35	120.0	2E7J1@1|root,33DKE@2|Bacteria,1VM3N@1239|Firmicutes,24VIG@186801|Clostridia,3Y0W5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03183	1121115.AXVN01000079_gene2738	5.72e-200	553.0	2BYUU@1|root,2Z7P3@2|Bacteria,1UYDK@1239|Firmicutes,249UN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03184	1121115.AXVN01000079_gene2739	2.96e-151	424.0	2C0W2@1|root,306ZY@2|Bacteria,1V5YY@1239|Firmicutes,24I0Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K07726	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3,HTH_7,MqsA_antitoxin
PKFBPKFJ_03185	1121115.AXVN01000079_gene2740	1.44e-131	373.0	COG0400@1|root,COG0400@2|Bacteria,1TXQZ@1239|Firmicutes,24GGB@186801|Clostridia,3Y0NJ@572511|Blautia	186801|Clostridia	S	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03186	1121115.AXVN01000079_gene2741	0.0	910.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,3Y1AK@572511|Blautia	186801|Clostridia	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
PKFBPKFJ_03187	457412.RSAG_02088	2.95e-160	448.0	COG1028@1|root,COG1028@2|Bacteria,1V0T9@1239|Firmicutes,24ASP@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
PKFBPKFJ_03188	1121115.AXVN01000079_gene2743	5.17e-123	351.0	COG3275@1|root,COG3275@2|Bacteria,1UZUT@1239|Firmicutes,25BAU@186801|Clostridia,3Y2E5@572511|Blautia	186801|Clostridia	T	phosphorelay sensor kinase activity	-	-	-	ko:K16923	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.28	-	-	ECF_trnsprt
PKFBPKFJ_03189	1121115.AXVN01000079_gene2744	9.97e-245	671.0	COG1957@1|root,COG1957@2|Bacteria,1TRQQ@1239|Firmicutes,25C8Y@186801|Clostridia,3Y2EI@572511|Blautia	186801|Clostridia	F	Inosine-uridine preferring nucleoside hydrolase	iunH	-	3.2.2.1	ko:K01239,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
PKFBPKFJ_03190	1121115.AXVN01000100_gene838	0.0	1664.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3XZ58@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
PKFBPKFJ_03191	457412.RSAG_00670	7.01e-213	596.0	COG2733@1|root,COG2733@2|Bacteria,1UKI3@1239|Firmicutes,24WBV@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
PKFBPKFJ_03192	1121115.AXVN01000100_gene837	2.18e-110	328.0	COG2733@1|root,COG2733@2|Bacteria,1UKI3@1239|Firmicutes,24WBV@186801|Clostridia	186801|Clostridia	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	RelA_SpoT
PKFBPKFJ_03193	1121115.AXVN01000100_gene836	6.45e-60	185.0	2CTB7@1|root,32VEP@2|Bacteria,1VD77@1239|Firmicutes,24KKI@186801|Clostridia,3Y0H9@572511|Blautia	186801|Clostridia	S	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	-	-	-	-	-	-	-	-	-	BMC
PKFBPKFJ_03194	1121115.AXVN01000100_gene835	1.21e-59	184.0	COG4577@1|root,COG4577@2|Bacteria,1VHU0@1239|Firmicutes,24PP6@186801|Clostridia,3Y0PM@572511|Blautia	186801|Clostridia	CQ	BMC	-	-	-	-	-	-	-	-	-	-	-	-	BMC
PKFBPKFJ_03195	1121115.AXVN01000100_gene834	1.05e-95	281.0	COG0663@1|root,COG0663@2|Bacteria,1V6CZ@1239|Firmicutes,24JAK@186801|Clostridia,3Y08H@572511|Blautia	186801|Clostridia	S	Hexapeptide repeat of succinyl-transferase	PaaY	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep,Hexapep_2
PKFBPKFJ_03196	1121115.AXVN01000100_gene833	2.03e-120	343.0	COG3194@1|root,COG3194@2|Bacteria,1VC6W@1239|Firmicutes,24HRJ@186801|Clostridia,3Y1H1@572511|Blautia	186801|Clostridia	F	Ureidoglycolate lyase	-	-	-	-	-	-	-	-	-	-	-	-	Ureidogly_lyase
PKFBPKFJ_03197	1121115.AXVN01000100_gene832	4.02e-195	542.0	COG4820@1|root,COG4820@2|Bacteria,1TQVV@1239|Firmicutes,249HD@186801|Clostridia,3Y15N@572511|Blautia	186801|Clostridia	E	Type IV pilus assembly protein PilM;	eutJ	-	-	ko:K04024	-	-	-	-	ko00000	-	-	-	FtsA,MreB_Mbl,PilM_2
PKFBPKFJ_03198	1121115.AXVN01000100_gene831	3.37e-162	455.0	COG0600@1|root,COG0600@2|Bacteria,1V73W@1239|Firmicutes,24A2R@186801|Clostridia,3Y1BD@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran,BPD_transp_1
PKFBPKFJ_03199	1121115.AXVN01000100_gene830	2.86e-93	272.0	COG1116@1|root,COG1116@2|Bacteria,1VAD8@1239|Firmicutes,24GFE@186801|Clostridia,3Y1PX@572511|Blautia	186801|Clostridia	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
PKFBPKFJ_03200	1121115.AXVN01000100_gene829	9.06e-260	710.0	COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,24AY7@186801|Clostridia,3XYJG@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N,ADH_zinc_N_2
PKFBPKFJ_03201	457412.RSAG_00661	1.16e-85	252.0	2DQ8F@1|root,3359H@2|Bacteria,1UKI2@1239|Firmicutes,25FXK@186801|Clostridia	186801|Clostridia	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
PKFBPKFJ_03202	1121115.AXVN01000100_gene827	1.76e-28	102.0	2FJB1@1|root,34B0Y@2|Bacteria,1VZVR@1239|Firmicutes,253R9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03203	1121115.AXVN01000100_gene826	5.97e-22	85.1	2DH0X@1|root,2ZY0F@2|Bacteria,1W4RB@1239|Firmicutes,254V8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03204	457412.RSAG_00659	0.0	932.0	COG4467@1|root,COG4467@2|Bacteria,1UK82@1239|Firmicutes,25FQ4@186801|Clostridia,3WSP3@541000|Ruminococcaceae	186801|Clostridia	S	Transposase IS66 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66
PKFBPKFJ_03205	457412.RSAG_01875	9.88e-235	645.0	COG1597@1|root,COG1597@2|Bacteria,1V7DZ@1239|Firmicutes,25CN5@186801|Clostridia	186801|Clostridia	I	Diacylglycerol kinase catalytic domain	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
PKFBPKFJ_03207	457412.RSAG_01877	1.14e-296	809.0	COG1277@1|root,COG1277@2|Bacteria,1UTUG@1239|Firmicutes,25EAK@186801|Clostridia,3WMG3@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
PKFBPKFJ_03208	457412.RSAG_01878	1.11e-206	572.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3WHDX@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03209	457412.RSAG_01879	1e-171	480.0	2DMFS@1|root,32R85@2|Bacteria,1U024@1239|Firmicutes,25MSI@186801|Clostridia,3WQUD@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03210	457412.RSAG_01880	2.52e-119	341.0	COG1595@1|root,COG1595@2|Bacteria,1VBJI@1239|Firmicutes,24NKR@186801|Clostridia,3WS7B@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_03211	457412.RSAG_01882	0.0	1163.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WGKA@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase catalytic	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
PKFBPKFJ_03212	457412.RSAG_01883	2.46e-247	679.0	COG1609@1|root,COG1609@2|Bacteria,1TS5M@1239|Firmicutes,24AWP@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
PKFBPKFJ_03213	457412.RSAG_01884	0.0	1171.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WGKA@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase catalytic	-	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459
PKFBPKFJ_03214	457412.RSAG_01885	3.54e-229	630.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1UVPR@1239|Firmicutes,25KKF@186801|Clostridia,3WPZY@541000|Ruminococcaceae	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PKFBPKFJ_03215	1121115.AXVN01000085_gene2195	5.47e-49	165.0	COG2182@1|root,COG2182@2|Bacteria,1UI14@1239|Firmicutes,25EA2@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
PKFBPKFJ_03217	457412.RSAG_01887	9.51e-295	801.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,249GP@186801|Clostridia,3WHHT@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
PKFBPKFJ_03218	457412.RSAG_01888	1.14e-196	546.0	COG0395@1|root,COG0395@2|Bacteria,1TSJ9@1239|Firmicutes,24ERB@186801|Clostridia	186801|Clostridia	P	abc transporter permease protein	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PKFBPKFJ_03219	457412.RSAG_01889	8.47e-207	572.0	COG1175@1|root,COG1175@2|Bacteria,1UXJV@1239|Firmicutes,25MIZ@186801|Clostridia,3WQ0J@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_03220	457412.RSAG_01890	4.53e-303	825.0	COG1653@1|root,COG1653@2|Bacteria,1TQJU@1239|Firmicutes,24AHT@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
PKFBPKFJ_03221	457412.RSAG_01891	0.0	1192.0	COG2972@1|root,COG2972@2|Bacteria,1TSE1@1239|Firmicutes,24B0H@186801|Clostridia	186801|Clostridia	T	HAMP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
PKFBPKFJ_03222	457412.RSAG_01892	0.0	1051.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TR4U@1239|Firmicutes,24JVF@186801|Clostridia,3WJ1J@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
PKFBPKFJ_03223	1121115.AXVN01000156_gene544	1.42e-177	496.0	COG4822@1|root,COG4822@2|Bacteria	2|Bacteria	H	anaerobic cobalamin biosynthetic process	cbiK	-	4.99.1.3	ko:K02006,ko:K02190	ko00860,ko01100,ko02010,map00860,map01100,map02010	M00245,M00246	R05807	RC01012	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran,CbiK,TP_methylase
PKFBPKFJ_03224	1121115.AXVN01000156_gene545	2.08e-112	323.0	COG5652@1|root,COG5652@2|Bacteria,1V72A@1239|Firmicutes,259NP@186801|Clostridia,3Y02J@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
PKFBPKFJ_03225	1121115.AXVN01000156_gene546	3.76e-97	284.0	2979U@1|root,2ZUHG@2|Bacteria,1W35F@1239|Firmicutes,256C8@186801|Clostridia,3Y0TR@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03226	1042156.CXIVA_01340	2.03e-250	687.0	COG0388@1|root,COG0388@2|Bacteria,1UYBG@1239|Firmicutes	1239|Firmicutes	S	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide	amiF	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
PKFBPKFJ_03227	457412.RSAG_00901	5.47e-151	424.0	COG0655@1|root,COG0655@2|Bacteria,1TT84@1239|Firmicutes,248W0@186801|Clostridia,3WJ1H@541000|Ruminococcaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
PKFBPKFJ_03228	1232447.BAHW02000027_gene2070	5.67e-24	96.3	2DP32@1|root,330AW@2|Bacteria,1VGSG@1239|Firmicutes,24Q56@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03229	411459.RUMOBE_01935	2.17e-32	114.0	2BCQI@1|root,326AY@2|Bacteria,1US91@1239|Firmicutes,25A84@186801|Clostridia,3Y22C@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03230	1256908.HMPREF0373_01452	5.72e-113	325.0	COG1813@1|root,COG1813@2|Bacteria,1V73A@1239|Firmicutes,24GZG@186801|Clostridia,25WVT@186806|Eubacteriaceae	186801|Clostridia	K	Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
PKFBPKFJ_03231	1256908.HMPREF0373_01453	6.16e-90	264.0	COG3064@1|root,COG3064@2|Bacteria,1VB1V@1239|Firmicutes,24BPB@186801|Clostridia,25Z12@186806|Eubacteriaceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03232	1256908.HMPREF0373_01454	5.62e-35	120.0	2DQE4@1|root,3368Z@2|Bacteria,1VJUF@1239|Firmicutes,24THC@186801|Clostridia,25Z51@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03233	411459.RUMOBE_01941	4.33e-16	70.5	28XTQ@1|root,2ZJQ5@2|Bacteria,1W1UB@1239|Firmicutes,254MH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03234	457412.RSAG_01903	6.05e-127	361.0	COG1443@1|root,COG1443@2|Bacteria,1V6SB@1239|Firmicutes,24HX1@186801|Clostridia,3WK9W@541000|Ruminococcaceae	186801|Clostridia	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
PKFBPKFJ_03235	457412.RSAG_01904	1.72e-114	328.0	COG0778@1|root,COG0778@2|Bacteria,1V4DP@1239|Firmicutes,24HBZ@186801|Clostridia,3WK3U@541000|Ruminococcaceae	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
PKFBPKFJ_03236	478749.BRYFOR_07795	3.47e-14	71.6	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system ATPase component	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
PKFBPKFJ_03237	699248.SRA_09581	0.000395	47.0	COG1396@1|root,COG1396@2|Bacteria,1VEGA@1239|Firmicutes,4IU06@91061|Bacilli	91061|Bacilli	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_03239	1408423.JHYA01000001_gene864	4.16e-106	326.0	2C6FM@1|root,2ZB1N@2|Bacteria,1UTIP@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03240	1121115.AXVN01000014_gene1228	4.55e-206	569.0	COG0491@1|root,COG0491@2|Bacteria,1V3ZB@1239|Firmicutes,25BG4@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
PKFBPKFJ_03241	1121115.AXVN01000014_gene1229	0.0	1045.0	COG2972@1|root,COG2972@2|Bacteria	2|Bacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
PKFBPKFJ_03242	1121115.AXVN01000014_gene1230	0.0	1025.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1VSN8@1239|Firmicutes,24YS7@186801|Clostridia,3Y1SB@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
PKFBPKFJ_03243	1121115.AXVN01000014_gene1231	5.4e-309	843.0	COG1373@1|root,COG1373@2|Bacteria,1TQ8Z@1239|Firmicutes,258AG@186801|Clostridia,3Y0AF@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4143)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
PKFBPKFJ_03244	1121115.AXVN01000014_gene1232	0.0	1031.0	COG0846@1|root,COG0846@2|Bacteria,1TUKR@1239|Firmicutes,249GZ@186801|Clostridia	186801|Clostridia	K	SIR2-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SIR2_2
PKFBPKFJ_03245	1121115.AXVN01000014_gene1234	9.18e-49	155.0	2DFQS@1|root,2ZSPZ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03246	1121115.AXVN01000014_gene1235	2.22e-93	273.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,3XYT6@572511|Blautia	186801|Clostridia	S	COG NOG08579 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
PKFBPKFJ_03247	457412.RSAG_03335	3.06e-67	203.0	COG1943@1|root,COG1943@2|Bacteria,1VAIQ@1239|Firmicutes,24IPG@186801|Clostridia,3WRVG@541000|Ruminococcaceae	186801|Clostridia	L	Transposase IS200 like	-	-	-	ko:K07491	-	-	-	-	ko00000	-	-	-	Y1_Tnp
PKFBPKFJ_03248	457412.RSAG_04608	0.0	895.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24FCE@186801|Clostridia,3WP1Z@541000|Ruminococcaceae	186801|Clostridia	L	TIGRFAM transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_IS605
PKFBPKFJ_03249	457412.RSAG_03338	3.48e-44	143.0	2CCVX@1|root,33G73@2|Bacteria,1VN7A@1239|Firmicutes,24W0K@186801|Clostridia,3WRAX@541000|Ruminococcaceae	186801|Clostridia	S	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
PKFBPKFJ_03250	457412.RSAG_03339	2.06e-38	128.0	2EMF6@1|root,33F40@2|Bacteria,1VPJF@1239|Firmicutes,24VFH@186801|Clostridia,3WQWU@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03251	457412.RSAG_04607	5.12e-38	127.0	298ED@1|root,2ZVJK@2|Bacteria,1W2SQ@1239|Firmicutes,2571M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03252	1121115.AXVN01000030_gene3643	2.2e-61	188.0	2CA4P@1|root,33W70@2|Bacteria,1VVK6@1239|Firmicutes,251F5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03253	1121115.AXVN01000030_gene3642	4.61e-167	468.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,3XZX5@572511|Blautia	186801|Clostridia	K	FCD domain	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
PKFBPKFJ_03254	397288.C806_02996	9.83e-12	67.8	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_03255	500632.CLONEX_03572	1.81e-23	90.9	2DE0W@1|root,2ZK1Y@2|Bacteria,1W4QD@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03256	1235798.C817_05064	5.79e-16	71.6	2EQGP@1|root,33I2P@2|Bacteria,1VKY1@1239|Firmicutes,24US2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03258	642492.Clole_1479	7.31e-22	97.8	COG3935@1|root,COG3935@2|Bacteria,1W6YJ@1239|Firmicutes,24P7D@186801|Clostridia	186801|Clostridia	L	DnaD domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03259	397291.C804_01604	8.11e-82	252.0	COG1484@1|root,COG1484@2|Bacteria,1V8DQ@1239|Firmicutes,24M56@186801|Clostridia,27NQC@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Bacterial dnaA  protein	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	Bac_DnaA,IstB_IS21
PKFBPKFJ_03260	742765.HMPREF9457_00651	2.36e-149	419.0	COG1073@1|root,COG1073@2|Bacteria,1U9AI@1239|Firmicutes,24B6Z@186801|Clostridia,27WE4@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
PKFBPKFJ_03261	457412.RSAG_00859	1.79e-88	259.0	2DH0B@1|root,2ZXXZ@2|Bacteria,1W4MJ@1239|Firmicutes,257EH@186801|Clostridia	457412.RSAG_00859|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03262	545696.HOLDEFILI_01786	6.86e-17	78.2	28IR3@1|root,2Z8QN@2|Bacteria,1UKI8@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791,DUF3990
PKFBPKFJ_03263	622312.ROSEINA2194_00607	7.62e-39	130.0	2E7JW@1|root,33220@2|Bacteria,1VFQV@1239|Firmicutes,24WME@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03265	1121115.AXVN01000045_gene2050	2.4e-161	452.0	COG0664@1|root,COG0664@2|Bacteria,1V39R@1239|Firmicutes,24C2I@186801|Clostridia,3XZTI@572511|Blautia	186801|Clostridia	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
PKFBPKFJ_03266	1121115.AXVN01000045_gene2051	5.86e-259	707.0	COG0479@1|root,COG0479@2|Bacteria,1TP8R@1239|Firmicutes,247QI@186801|Clostridia,3XZSA@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4_22
PKFBPKFJ_03267	1121115.AXVN01000045_gene2052	1.02e-192	534.0	COG0543@1|root,COG0543@2|Bacteria,1TQBZ@1239|Firmicutes,248GQ@186801|Clostridia,3XYPT@572511|Blautia	186801|Clostridia	C	Oxidoreductase NAD-binding domain	asrB	-	-	ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
PKFBPKFJ_03268	1121115.AXVN01000045_gene2053	1.19e-232	640.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,3XZCG@572511|Blautia	186801|Clostridia	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	asrC	-	-	ko:K00385	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4,Fer4_10,Fer4_21,Fer4_4,Fer4_6,NIR_SIR,NIR_SIR_ferr
PKFBPKFJ_03269	457412.RSAG_00856	0.0	1056.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,3WGG6@541000|Ruminococcaceae	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
PKFBPKFJ_03270	457412.RSAG_00855	4.86e-175	487.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,3WGU7@541000|Ruminococcaceae	186801|Clostridia	C	4Fe-4S binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
PKFBPKFJ_03271	457412.RSAG_00854	9.41e-164	458.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3WIW5@541000|Ruminococcaceae	186801|Clostridia	K	Cyclic nucleotide-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
PKFBPKFJ_03272	457412.RSAG_00853	0.0	1720.0	COG0642@1|root,COG0784@1|root,COG2203@1|root,COG0784@2|Bacteria,COG2203@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WN7G@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HATPase_c,HisKA,PAS_9,Response_reg
PKFBPKFJ_03273	457412.RSAG_00852	0.0	1329.0	COG0642@1|root,COG3452@1|root,COG0642@2|Bacteria,COG3452@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Response_reg,dCache_1
PKFBPKFJ_03274	457412.RSAG_00851	3.48e-246	676.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,3WRV6@541000|Ruminococcaceae	186801|Clostridia	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
PKFBPKFJ_03275	457412.RSAG_00850	1.18e-308	843.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3WGER@541000|Ruminococcaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_03276	457412.RSAG_00849	2.35e-176	493.0	2DM3M@1|root,31JZR@2|Bacteria,1V8CM@1239|Firmicutes,24KFB@186801|Clostridia	186801|Clostridia	M	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
PKFBPKFJ_03277	457412.RSAG_00848	0.0	2375.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia,3WH59@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03278	457412.RSAG_00847	4.42e-312	848.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia,3WK5B@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03279	457412.RSAG_00846	1.36e-173	486.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24D1P@186801|Clostridia,3WJTT@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
PKFBPKFJ_03280	457412.RSAG_04762	2.25e-189	528.0	COG0834@1|root,COG0834@2|Bacteria,1TQNR@1239|Firmicutes,249Y5@186801|Clostridia,3WH7X@541000|Ruminococcaceae	186801|Clostridia	ET	Belongs to the bacterial solute-binding protein 3 family	fliY1	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
PKFBPKFJ_03281	1121115.AXVN01000045_gene2069	9.94e-134	381.0	COG0765@1|root,COG0765@2|Bacteria,1V280@1239|Firmicutes,25C2S@186801|Clostridia,3XYV9@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	tcyB	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
PKFBPKFJ_03282	1121115.AXVN01000045_gene2070	2.04e-157	442.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3XZJ5@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
PKFBPKFJ_03283	1121115.AXVN01000045_gene2071	0.0	930.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3XZ1Q@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
PKFBPKFJ_03284	1121115.AXVN01000045_gene2072	0.0	872.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3XYKX@572511|Blautia	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
PKFBPKFJ_03285	1121115.AXVN01000045_gene2073	6.42e-198	548.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia,3XZZB@572511|Blautia	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
PKFBPKFJ_03286	1121115.AXVN01000006_gene2188	1.52e-124	354.0	COG3012@1|root,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia,3XZU8@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
PKFBPKFJ_03287	457412.RSAG_00839	1.63e-122	349.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia	186801|Clostridia	O	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
PKFBPKFJ_03288	1121115.AXVN01000006_gene2186	2.04e-209	579.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3XYQC@572511|Blautia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
PKFBPKFJ_03289	1121115.AXVN01000006_gene2185	4.58e-204	565.0	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,24HI3@186801|Clostridia,3Y05C@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	spoIIGA	-	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
PKFBPKFJ_03290	1121115.AXVN01000006_gene2184	5.6e-159	446.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,3XZGI@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
PKFBPKFJ_03291	1121115.AXVN01000006_gene2183	1.13e-240	661.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,3XZB3@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
PKFBPKFJ_03292	1121115.AXVN01000006_gene2182	0.0	919.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,3XYTG@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
PKFBPKFJ_03293	1121115.AXVN01000006_gene2181	0.0	868.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,3XZ02@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
PKFBPKFJ_03294	1121115.AXVN01000006_gene2180	2.31e-115	331.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,3XYJ2@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
PKFBPKFJ_03295	457412.RSAG_00801	0.0	916.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,25B5K@186801|Clostridia,3WIPD@541000|Ruminococcaceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_03296	1121115.AXVN01000006_gene2178	3.28e-128	364.0	COG4636@1|root,COG4636@2|Bacteria,1V1Q1@1239|Firmicutes,24G9A@186801|Clostridia,3Y058@572511|Blautia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
PKFBPKFJ_03297	1256908.HMPREF0373_00641	5.15e-154	455.0	COG1196@1|root,COG1196@2|Bacteria,1UI77@1239|Firmicutes,25ECC@186801|Clostridia	186801|Clostridia	D	T5orf172	-	-	-	-	-	-	-	-	-	-	-	-	DUF4041,MUG113,T5orf172
PKFBPKFJ_03298	457412.RSAG_00798	5.44e-99	288.0	COG2856@1|root,COG2856@2|Bacteria,1V4N6@1239|Firmicutes,24JDG@186801|Clostridia,3WQH6@541000|Ruminococcaceae	186801|Clostridia	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
PKFBPKFJ_03299	1121115.AXVN01000006_gene2175	2.73e-50	159.0	arCOG06833@1|root,32SGF@2|Bacteria,1U5WJ@1239|Firmicutes,25K3K@186801|Clostridia,3Y0UZ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03300	457412.RSAG_00796	1.35e-71	215.0	arCOG07672@1|root,32Z5Y@2|Bacteria,1VG6R@1239|Firmicutes,24T0M@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4258)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4258
PKFBPKFJ_03301	665956.HMPREF1032_04076	1.4e-21	95.1	COG1396@1|root,COG1974@1|root,COG1396@2|Bacteria,COG1974@2|Bacteria,1UHUG@1239|Firmicutes,25E2W@186801|Clostridia,3WRC7@541000|Ruminococcaceae	186801|Clostridia	K	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Peptidase_S24
PKFBPKFJ_03302	97139.C824_00056	2.25e-09	55.8	2A6FG@1|root,30V8E@2|Bacteria,1UQVA@1239|Firmicutes,24V0V@186801|Clostridia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
PKFBPKFJ_03304	1173020.Cha6605_3867	6.04e-18	77.0	COG0433@1|root,COG0433@2|Bacteria,1GQHB@1117|Cyanobacteria	1117|Cyanobacteria	S	KTSC domain	-	-	-	-	-	-	-	-	-	-	-	-	KTSC
PKFBPKFJ_03308	1121115.AXVN01000006_gene2172	2.82e-26	96.7	2FGK7@1|root,348FZ@2|Bacteria,1W09F@1239|Firmicutes,25375@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03312	272947.RP726	5.9e-10	61.2	COG0328@1|root,COG0328@2|Bacteria,1RCZ1@1224|Proteobacteria,2U7C4@28211|Alphaproteobacteria,47FDC@766|Rickettsiales	766|Rickettsiales	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
PKFBPKFJ_03313	483218.BACPEC_01167	9.58e-21	90.9	2F1A0@1|root,33UB0@2|Bacteria,1VUUK@1239|Firmicutes,24Q4U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03314	411902.CLOBOL_05698	4.59e-32	121.0	COG5164@1|root,COG5164@2|Bacteria,1V30J@1239|Firmicutes,24G8J@186801|Clostridia,220NZ@1506553|Lachnoclostridium	186801|Clostridia	K	regulation of DNA-templated transcription, elongation	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03315	411902.CLOBOL_05697	2.01e-149	459.0	28KSN@1|root,31D8D@2|Bacteria,1V6SJ@1239|Firmicutes,24BTZ@186801|Clostridia,21XT6@1506553|Lachnoclostridium	186801|Clostridia	S	PcfJ-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PcfJ
PKFBPKFJ_03316	1280698.AUJS01000007_gene1019	2.94e-44	168.0	2EAE3@1|root,334HP@2|Bacteria,1VHM2@1239|Firmicutes,24K95@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03317	1235798.C817_05493	1.85e-21	87.0	2EJY1@1|root,33DNP@2|Bacteria,1VKTV@1239|Firmicutes,24VPW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03318	693746.OBV_24070	8.12e-17	77.4	2CEPU@1|root,30FWJ@2|Bacteria,1UESN@1239|Firmicutes,25PBZ@186801|Clostridia,2N8HU@216572|Oscillospiraceae	693746.OBV_24070|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03322	411459.RUMOBE_00943	1.52e-59	187.0	2DS3B@1|root,33EBS@2|Bacteria,1VM4J@1239|Firmicutes,24N4N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03325	1298920.KI911353_gene4857	1.08e-67	210.0	COG3728@1|root,COG3728@2|Bacteria,1VCDW@1239|Firmicutes,25CX1@186801|Clostridia,2238Z@1506553|Lachnoclostridium	186801|Clostridia	L	Terminase small subunit	-	-	-	ko:K07474	-	-	-	-	ko00000	-	-	-	Terminase_2
PKFBPKFJ_03326	742740.HMPREF9474_03500	1.68e-250	694.0	COG1783@1|root,COG1783@2|Bacteria,1UZSU@1239|Firmicutes,25MKZ@186801|Clostridia,221EU@1506553|Lachnoclostridium	186801|Clostridia	S	Phage terminase, large subunit, PBSX family	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03327	742740.HMPREF9474_03501	3.92e-259	724.0	2DB9Q@1|root,2Z7Y9@2|Bacteria,1TRTY@1239|Firmicutes,24ANQ@186801|Clostridia,221T2@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_prot_Gp6
PKFBPKFJ_03328	742740.HMPREF9474_03502	3.13e-27	101.0	2EAUD@1|root,334W1@2|Bacteria,1VISF@1239|Firmicutes,24TKP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03329	33035.JPJF01000093_gene2255	2.34e-254	714.0	COG5585@1|root,COG5585@2|Bacteria,1UZ0K@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ADPrib_exo_Tox,Phage_min_cap2
PKFBPKFJ_03332	1304866.K413DRAFT_0806	2.91e-57	187.0	29H3I@1|root,30413@2|Bacteria,1V497@1239|Firmicutes,24HIA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03333	663278.Ethha_1589	1.45e-136	396.0	2CGZW@1|root,2Z7Z5@2|Bacteria,1UVRJ@1239|Firmicutes,24AW4@186801|Clostridia,3WSER@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03334	742740.HMPREF9474_03507	1.16e-62	194.0	2BVG1@1|root,32QV3@2|Bacteria,1V7ZP@1239|Firmicutes,24K5D@186801|Clostridia,222XF@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03335	742740.HMPREF9474_03508	2.88e-44	146.0	2DRD5@1|root,32UQW@2|Bacteria,1VDZ1@1239|Firmicutes,24P34@186801|Clostridia,223E6@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03336	742740.HMPREF9474_03509	9.17e-57	179.0	2CEQV@1|root,32S0A@2|Bacteria,1VBZ1@1239|Firmicutes,25D42@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03338	33035.JPJF01000093_gene2246	2.65e-63	198.0	2CPV6@1|root,32SJY@2|Bacteria,1VCAK@1239|Firmicutes,24HJI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03339	33035.JPJF01000093_gene2245	6.5e-23	92.0	2E9HP@1|root,333QS@2|Bacteria,1VJM6@1239|Firmicutes,24TQB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03340	483218.BACPEC_01147	1.3e-15	71.6	2EFFA@1|root,33983@2|Bacteria,1VJ6U@1239|Firmicutes,24MSJ@186801|Clostridia,26C6R@186813|unclassified Clostridiales	186801|Clostridia	S	Bacteriophage Gp15 protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_Gp15
PKFBPKFJ_03341	33035.JPJF01000093_gene2243	1.32e-255	747.0	COG3941@1|root,COG5412@1|root,COG3941@2|Bacteria,COG5412@2|Bacteria,1TQDE@1239|Firmicutes,249I0@186801|Clostridia,3Y0ZQ@572511|Blautia	186801|Clostridia	S	phage tail tape measure protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03342	33035.JPJF01000093_gene2242	2.04e-47	155.0	2DTNS@1|root,33M3M@2|Bacteria,1VM94@1239|Firmicutes,24VR3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03345	411459.RUMOBE_00923	6.42e-258	760.0	COG4926@1|root,COG4926@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	CBM_4_9,Peptidase_S74,Prophage_tail
PKFBPKFJ_03346	411459.RUMOBE_04220	1.9e-20	93.6	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
PKFBPKFJ_03347	411459.RUMOBE_00920	6.77e-208	578.0	COG4974@1|root,COG4974@2|Bacteria,1TQXV@1239|Firmicutes,24884@186801|Clostridia,3Y00R@572511|Blautia	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
PKFBPKFJ_03348	1232453.BAIF02000059_gene1614	8.42e-11	73.6	2DPY0@1|root,333VQ@2|Bacteria,1VFC3@1239|Firmicutes,24Q3Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03349	1226322.HMPREF1545_04027	7.09e-10	57.4	2DRAZ@1|root,33B0U@2|Bacteria,1VN37@1239|Firmicutes,24WNH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03350	1121115.AXVN01000006_gene2171	1.99e-58	181.0	2CJIG@1|root,32SA4@2|Bacteria,1VCKV@1239|Firmicutes,24P9C@186801|Clostridia,3Y0FM@572511|Blautia	186801|Clostridia	S	Phage holin family Hol44, in holin superfamily V	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_5_2
PKFBPKFJ_03351	1121115.AXVN01000006_gene2170	0.0	954.0	COG3409@1|root,COG3757@1|root,COG3409@2|Bacteria,COG3757@2|Bacteria,1VDIK@1239|Firmicutes,25FZ8@186801|Clostridia,3Y00U@572511|Blautia	186801|Clostridia	M	autolytic lysozime (1,4-beta-N-acetylmuramidase), family 25 of glycosyl hydrolases	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Glyco_hydro_25
PKFBPKFJ_03352	411459.RUMOBE_00968	1.17e-17	73.9	COG3546@1|root,COG3546@2|Bacteria,1UF7I@1239|Firmicutes,25K8A@186801|Clostridia,3Y21Y@572511|Blautia	186801|Clostridia	P	Manganese containing catalase	-	-	-	-	-	-	-	-	-	-	-	-	Mn_catalase
PKFBPKFJ_03353	1121115.AXVN01000006_gene2169	1.35e-64	196.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia,3Y0NH@572511|Blautia	186801|Clostridia	S	COG NOG18028 non supervised orthologous group	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
PKFBPKFJ_03354	1121115.AXVN01000006_gene2168	3.28e-50	161.0	2EHCX@1|root,33B4S@2|Bacteria,1VKA0@1239|Firmicutes,259R7@186801|Clostridia,3Y0T8@572511|Blautia	186801|Clostridia	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA
PKFBPKFJ_03355	457412.RSAG_00787	1.35e-199	551.0	COG1234@1|root,COG1234@2|Bacteria,1TPSW@1239|Firmicutes,249RR@186801|Clostridia,3WIQB@541000|Ruminococcaceae	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
PKFBPKFJ_03356	1121115.AXVN01000006_gene2166	4.17e-157	440.0	COG1309@1|root,COG1309@2|Bacteria,1V3ZS@1239|Firmicutes,24H9U@186801|Clostridia,3XZV5@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PKFBPKFJ_03357	1121115.AXVN01000006_gene2165	0.0	1298.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,3XYKA@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
PKFBPKFJ_03358	1121115.AXVN01000006_gene2164	1.17e-271	793.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3XYKM@572511|Blautia	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
PKFBPKFJ_03359	1121115.AXVN01000006_gene2163	6.22e-267	733.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3XYUT@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
PKFBPKFJ_03360	1121115.AXVN01000006_gene2162	1.02e-46	150.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3Y0HG@572511|Blautia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
PKFBPKFJ_03361	1121115.AXVN01000006_gene2161	2.44e-213	590.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3XZKW@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
PKFBPKFJ_03362	457412.RSAG_00780	2.03e-166	466.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3WGIW@541000|Ruminococcaceae	186801|Clostridia	IQ	reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
PKFBPKFJ_03363	457412.RSAG_00779	6.9e-298	812.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3WGGB@541000|Ruminococcaceae	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
PKFBPKFJ_03364	1121115.AXVN01000006_gene2158	6.65e-99	288.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3Y0FB@572511|Blautia	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iHN637.CLJU_RS20755	Biotin_lipoyl
PKFBPKFJ_03365	1121115.AXVN01000006_gene2157	1.23e-96	281.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,3Y04Q@572511|Blautia	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
PKFBPKFJ_03366	1121115.AXVN01000006_gene2156	0.0	887.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,3XZMB@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
PKFBPKFJ_03367	1121115.AXVN01000006_gene2155	0.0	1122.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,3XYX8@572511|Blautia	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
PKFBPKFJ_03368	1121115.AXVN01000006_gene2154	0.0	977.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3XZIU@572511|Blautia	186801|Clostridia	H	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
PKFBPKFJ_03369	457412.RSAG_00773	0.0	1157.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,3WGMT@541000|Ruminococcaceae	186801|Clostridia	L	helicase	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
PKFBPKFJ_03370	1121115.AXVN01000006_gene2152	2.8e-135	382.0	COG2091@1|root,COG2091@2|Bacteria,1UFUD@1239|Firmicutes,25MRV@186801|Clostridia,3Y03Q@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
PKFBPKFJ_03371	1121115.AXVN01000006_gene2151	1.28e-265	727.0	COG3391@1|root,COG3391@2|Bacteria,1V841@1239|Firmicutes,24K83@186801|Clostridia,3Y0X1@572511|Blautia	186801|Clostridia	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03372	457412.RSAG_00770	2.52e-217	600.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,3WGH3@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AA	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
PKFBPKFJ_03373	1121115.AXVN01000006_gene2149	4.35e-120	343.0	2CEWW@1|root,3181X@2|Bacteria,1U7IP@1239|Firmicutes,2590I@186801|Clostridia,3Y0MY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06391	-	-	-	-	ko00000	-	-	-	Spore_III_AB
PKFBPKFJ_03374	457412.RSAG_00768	9.49e-35	119.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,3WKGF@541000|Ruminococcaceae	186801|Clostridia	S	stage III sporulation protein AC	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
PKFBPKFJ_03375	1121115.AXVN01000006_gene2147	1.25e-80	240.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia,3Y0FF@572511|Blautia	186801|Clostridia	S	COG NOG13205 non supervised orthologous group	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
PKFBPKFJ_03376	457412.RSAG_00766	1.6e-270	743.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia,3WITJ@541000|Ruminococcaceae	186801|Clostridia	S	Stage III sporulation protein	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
PKFBPKFJ_03377	457412.RSAG_00765	9.6e-125	356.0	29TPZ@1|root,30EY4@2|Bacteria,1UD4F@1239|Firmicutes,2591T@186801|Clostridia,3WMKP@541000|Ruminococcaceae	186801|Clostridia	S	Stage III sporulation protein AF (Spore_III_AF)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_III_AF
PKFBPKFJ_03378	1121115.AXVN01000006_gene2144	1.19e-63	195.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia,3Y0J8@572511|Blautia	186801|Clostridia	S	COG NOG11553 non supervised orthologous group	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
PKFBPKFJ_03379	457412.RSAG_00763	4.89e-160	450.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,3WITN@541000|Ruminococcaceae	186801|Clostridia	S	SpoIIIAH-like protein	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
PKFBPKFJ_03380	457412.RSAG_00762	0.0	1053.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,3WGUR@541000|Ruminococcaceae	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
PKFBPKFJ_03381	1121115.AXVN01000006_gene2141	8.03e-79	235.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,3Y075@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
PKFBPKFJ_03382	1121115.AXVN01000006_gene2140	5.6e-73	219.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,3Y08R@572511|Blautia	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
PKFBPKFJ_03383	1121115.AXVN01000006_gene2139	1.17e-272	748.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,3XZS9@572511|Blautia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
PKFBPKFJ_03384	1121115.AXVN01000006_gene2138	7.07e-48	153.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia,3Y0QF@572511|Blautia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
PKFBPKFJ_03385	457412.RSAG_00757	7.21e-205	567.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,3WINP@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the FPP GGPP synthase family	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
PKFBPKFJ_03386	1121115.AXVN01000006_gene2136	0.0	1236.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3XYQF@572511|Blautia	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
PKFBPKFJ_03387	457412.RSAG_00755	5.27e-194	538.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3WGGG@541000|Ruminococcaceae	186801|Clostridia	J	Ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
PKFBPKFJ_03388	1121115.AXVN01000006_gene2134	5.1e-205	567.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,3XZAI@572511|Blautia	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
PKFBPKFJ_03389	457412.RSAG_00753	6.17e-99	288.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,3WJZ0@541000|Ruminococcaceae	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
PKFBPKFJ_03390	457412.RSAG_00752	0.0	1028.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3WHDP@541000|Ruminococcaceae	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
PKFBPKFJ_03391	1121115.AXVN01000006_gene2131	5.39e-292	797.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia,3XZ8A@572511|Blautia	186801|Clostridia	T	stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
PKFBPKFJ_03392	457412.RSAG_00750	6.11e-188	522.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia,3WGU4@541000|Ruminococcaceae	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
PKFBPKFJ_03393	1121115.AXVN01000006_gene2129	0.0	1001.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3XYMY@572511|Blautia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
PKFBPKFJ_03394	1121115.AXVN01000006_gene2128	3.38e-251	689.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3XZ9Q@572511|Blautia	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
PKFBPKFJ_03395	457412.RSAG_00747	1.85e-130	371.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia,3WM72@541000|Ruminococcaceae	186801|Clostridia	S	RecX family	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
PKFBPKFJ_03396	457412.RSAG_00746	2.79e-299	825.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3WGE5@541000|Ruminococcaceae	186801|Clostridia	D	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
PKFBPKFJ_03397	457412.RSAG_00744	6.99e-136	385.0	2DUTP@1|root,33S73@2|Bacteria,1US3V@1239|Firmicutes,25A29@186801|Clostridia,3WR2A@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03398	457412.RSAG_00743	7.57e-211	582.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3WHQU@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
PKFBPKFJ_03400	1121115.AXVN01000006_gene2123	2.12e-253	694.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,3XYX3@572511|Blautia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
PKFBPKFJ_03401	457412.RSAG_00741	2.86e-304	831.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3WGTJ@541000|Ruminococcaceae	186801|Clostridia	S	Stage V sporulation protein B	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
PKFBPKFJ_03402	1121115.AXVN01000006_gene2121	1.09e-104	303.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3Y0AW@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
PKFBPKFJ_03403	1121115.AXVN01000006_gene2120	1.58e-283	775.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XZ67@572511|Blautia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
PKFBPKFJ_03404	1121115.AXVN01000006_gene2119	6.48e-104	300.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3XZVP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
PKFBPKFJ_03405	457412.RSAG_00737	0.0	1590.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3WHCP@541000|Ruminococcaceae	186801|Clostridia	P	E1-E2 ATPase	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	Cation_ATPase_N,E1-E2_ATPase,Hydrolase
PKFBPKFJ_03406	457412.RSAG_04756	0.0	1313.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3WH4U@541000|Ruminococcaceae	186801|Clostridia	G	Alpha amylase, catalytic domain	ams	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
PKFBPKFJ_03407	457412.RSAG_00734	4.05e-204	563.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,3WHRZ@541000|Ruminococcaceae	186801|Clostridia	E	histidinol phosphate phosphatase HisJ family	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
PKFBPKFJ_03408	1121115.AXVN01000006_gene2115	2.84e-240	660.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
PKFBPKFJ_03409	457412.RSAG_00732	4.58e-289	789.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3WGM9@541000|Ruminococcaceae	186801|Clostridia	G	Phosphoglycerate kinase	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
PKFBPKFJ_03410	457412.RSAG_00731	6.35e-176	490.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3WGWY@541000|Ruminococcaceae	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
PKFBPKFJ_03411	1121115.AXVN01000006_gene2112	1.8e-290	792.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZS4@572511|Blautia	186801|Clostridia	J	tRNA (Uracil-5-)-methyltransferase	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
PKFBPKFJ_03412	457412.RSAG_00729	2.49e-114	327.0	COG0454@1|root,COG0456@2|Bacteria,1V6Z8@1239|Firmicutes,24JT6@186801|Clostridia,3WSRJ@541000|Ruminococcaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
PKFBPKFJ_03413	457412.RSAG_00728	0.0	918.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,3WGT3@541000|Ruminococcaceae	186801|Clostridia	S	Oxidoreductase	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
PKFBPKFJ_03414	457412.RSAG_00727	1.76e-39	131.0	COG3655@1|root,COG3655@2|Bacteria,1TU95@1239|Firmicutes,25804@186801|Clostridia,3WQZ7@541000|Ruminococcaceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
PKFBPKFJ_03415	457412.RSAG_00726	3.32e-56	174.0	2C1AP@1|root,33ZCD@2|Bacteria,1VYDT@1239|Firmicutes,2529X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03416	457412.RSAG_00725	1.22e-308	841.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3WGKB@541000|Ruminococcaceae	186801|Clostridia	E	Homoserine dehydrogenase	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
PKFBPKFJ_03417	457412.RSAG_00723	0.0	1036.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3WGBI@541000|Ruminococcaceae	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
PKFBPKFJ_03418	457412.RSAG_00722	3.95e-308	841.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3WGKU@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_03419	457412.RSAG_00721	0.0	1050.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3WH27@541000|Ruminococcaceae	186801|Clostridia	S	ErfK YbiS YcfS YnhG	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
PKFBPKFJ_03420	1121115.AXVN01000006_gene2103	7.1e-44	144.0	2DWAP@1|root,33ZBJ@2|Bacteria,1VWWH@1239|Firmicutes,25203@186801|Clostridia,3Y23P@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
PKFBPKFJ_03421	457412.RSAG_00719	5.67e-258	706.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,3WH2W@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
PKFBPKFJ_03422	457412.RSAG_00718	1.72e-245	674.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia,3WSRI@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyltransferase like family 2	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
PKFBPKFJ_03423	457412.RSAG_00717	1.76e-162	454.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,3WJUP@541000|Ruminococcaceae	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
PKFBPKFJ_03424	457412.RSAG_00716	3.04e-156	438.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24EFS@186801|Clostridia,3WRPD@541000|Ruminococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03425	457412.RSAG_00715	0.0	1459.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3WGKN@541000|Ruminococcaceae	186801|Clostridia	L	DNA topoisomerase III	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
PKFBPKFJ_03426	1121115.AXVN01000061_gene489	7.23e-85	250.0	2DRY9@1|root,33DNC@2|Bacteria,1VJXZ@1239|Firmicutes,25NY6@186801|Clostridia,3Y0SG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03427	457412.RSAG_00713	3.06e-165	461.0	COG0727@1|root,COG0727@2|Bacteria,1TT6P@1239|Firmicutes,24BWS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
PKFBPKFJ_03428	457412.RSAG_00712	8.73e-191	529.0	COG2207@1|root,COG2207@2|Bacteria,1UZ5U@1239|Firmicutes,24DJM@186801|Clostridia,3WJ5M@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
PKFBPKFJ_03429	457412.RSAG_00711	0.0	1605.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,3WGK9@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyltransferase family 36	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
PKFBPKFJ_03430	457412.RSAG_00710	0.0	1829.0	COG3459@1|root,COG3459@2|Bacteria,1UYFP@1239|Firmicutes,24A8A@186801|Clostridia,3WH9Q@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase 36 superfamily, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
PKFBPKFJ_03431	457412.RSAG_00709	0.0	929.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WHES@541000|Ruminococcaceae	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
PKFBPKFJ_03432	1121115.AXVN01000061_gene495	6.23e-217	600.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia,3Y17Y@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PKFBPKFJ_03433	1121115.AXVN01000061_gene496	8.11e-179	500.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,3Y023@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PKFBPKFJ_03434	457412.RSAG_00706	0.0	1656.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3WGRC@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolase family 3 N-terminal domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
PKFBPKFJ_03435	457412.RSAG_00705	6.72e-313	849.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,3WIXE@541000|Ruminococcaceae	186801|Clostridia	S	N-methylation of lysine residues in flagellin K00599	fliU	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
PKFBPKFJ_03436	457412.RSAG_00704	4.58e-184	513.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,3WIGP@541000|Ruminococcaceae	186801|Clostridia	K	transcriptional regulator AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
PKFBPKFJ_03437	1121115.AXVN01000061_gene500	0.0	1441.0	COG5426@1|root,COG5426@2|Bacteria,1TPH0@1239|Firmicutes,24892@186801|Clostridia,3XZ5G@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	gnpA	GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704	2.4.1.211	ko:K15533	-	-	-	-	ko00000,ko01000	-	-	-	LBP_C,LBP_M,Lact_bio_phlase
PKFBPKFJ_03438	457412.RSAG_00702	1.29e-259	711.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3WGS4@541000|Ruminococcaceae	186801|Clostridia	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
PKFBPKFJ_03439	457412.RSAG_00701	0.0	972.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3WNM6@541000|Ruminococcaceae	186801|Clostridia	O	PrkA AAA domain	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
PKFBPKFJ_03440	457412.RSAG_00700	6.35e-278	759.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,1TP4F@1239|Firmicutes,248MM@186801|Clostridia,3WG7W@541000|Ruminococcaceae	186801|Clostridia	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
PKFBPKFJ_03441	457412.RSAG_00699	1.83e-149	421.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia,3WIGR@541000|Ruminococcaceae	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
PKFBPKFJ_03442	457412.RSAG_00698	9.66e-292	796.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1TPH9@1239|Firmicutes,248B0@186801|Clostridia,3WGA9@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
PKFBPKFJ_03443	457412.RSAG_00697	2.6e-106	306.0	COG0054@1|root,COG0054@2|Bacteria,1V1DA@1239|Firmicutes,24FRS@186801|Clostridia,3WINK@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin	ribH	-	2.5.1.78	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R04457	RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	DMRL_synthase
PKFBPKFJ_03444	457412.RSAG_00696	5.62e-252	691.0	COG0564@1|root,COG0564@2|Bacteria,1VS66@1239|Firmicutes,25M7T@186801|Clostridia,3WP3U@541000|Ruminococcaceae	186801|Clostridia	J	RNA pseudouridylate synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
PKFBPKFJ_03445	457412.RSAG_00695	3.65e-222	612.0	COG1893@1|root,COG1893@2|Bacteria,1TSZ1@1239|Firmicutes,249UK@186801|Clostridia,3WGSB@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
PKFBPKFJ_03446	1121115.AXVN01000043_gene3367	0.0	1072.0	COG1866@1|root,COG1866@2|Bacteria,1TPQV@1239|Firmicutes,248JE@186801|Clostridia,3XYJY@572511|Blautia	186801|Clostridia	H	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA	pckA	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
PKFBPKFJ_03447	457412.RSAG_00693	6.3e-142	405.0	2E03H@1|root,333DZ@2|Bacteria,1VJ8Q@1239|Firmicutes,24RNP@186801|Clostridia,3WRYM@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03448	457412.RSAG_00692	1.04e-76	228.0	COG1393@1|root,COG1393@2|Bacteria,1V6H8@1239|Firmicutes,24JH6@186801|Clostridia,3WK00@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC,Glutaredoxin
PKFBPKFJ_03449	457412.RSAG_00691	6.73e-243	667.0	COG4637@1|root,COG4637@2|Bacteria,1V0EX@1239|Firmicutes,24B14@186801|Clostridia,3WIPF@541000|Ruminococcaceae	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21,AAA_23
PKFBPKFJ_03450	457412.RSAG_00690	1.35e-119	342.0	28P26@1|root,2ZBYA@2|Bacteria,1V1VU@1239|Firmicutes,24GBU@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03451	457412.RSAG_00689	2.69e-114	327.0	COG4728@1|root,COG4728@2|Bacteria,1VENJ@1239|Firmicutes,24SFD@186801|Clostridia,3WMPN@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF1653)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1653
PKFBPKFJ_03452	457412.RSAG_00688	2.42e-122	348.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24HQM@186801|Clostridia,3WJG3@541000|Ruminococcaceae	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
PKFBPKFJ_03453	457412.RSAG_00687	5.99e-143	403.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,3WHRM@541000|Ruminococcaceae	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
PKFBPKFJ_03454	457412.RSAG_00686	5.57e-147	413.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,Methyltransf_23,Methyltransf_25,PLDc_2,ResIII
PKFBPKFJ_03455	457412.RSAG_00685	0.0	1657.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,3WHD8@541000|Ruminococcaceae	186801|Clostridia	L	helicase C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
PKFBPKFJ_03456	457412.RSAG_00684	1.16e-205	568.0	28N02@1|root,2ZB6N@2|Bacteria,1UZ98@1239|Firmicutes,24FB2@186801|Clostridia,3WNNW@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03457	457412.RSAG_00683	2.05e-255	700.0	2A09X@1|root,30NDB@2|Bacteria,1UK3C@1239|Firmicutes,24HJN@186801|Clostridia,3WPU1@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NA37
PKFBPKFJ_03458	457412.RSAG_00682	0.0	949.0	28M7C@1|root,2ZAKU@2|Bacteria,1UY44@1239|Firmicutes,24FB5@186801|Clostridia,3WPXK@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03459	457412.RSAG_00673	9.29e-307	838.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,3WHDK@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_03460	457412.RSAG_00674	7.42e-257	702.0	COG2267@1|root,COG2267@2|Bacteria,1V2IH@1239|Firmicutes,24BN4@186801|Clostridia,3WPQY@541000|Ruminococcaceae	186801|Clostridia	I	Alpha/beta hydrolase family	-	-	3.1.1.5	ko:K01048	ko00564,map00564	-	-	-	ko00000,ko00001,ko01000	-	-	-	Hydrolase_4
PKFBPKFJ_03461	457412.RSAG_00675	0.0	877.0	COG2211@1|root,COG2211@2|Bacteria,1TR5B@1239|Firmicutes,249ZF@186801|Clostridia,3WGZS@541000|Ruminococcaceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
PKFBPKFJ_03462	1121115.AXVN01000043_gene3385	3.41e-182	506.0	COG0483@1|root,COG0483@2|Bacteria,1TR4E@1239|Firmicutes,24KJZ@186801|Clostridia,3Y085@572511|Blautia	186801|Clostridia	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
PKFBPKFJ_03463	1121115.AXVN01000043_gene3384	0.0	1055.0	COG1672@1|root,COG1672@2|Bacteria,1TQQ5@1239|Firmicutes,24918@186801|Clostridia,3Y131@572511|Blautia	186801|Clostridia	S	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PKFBPKFJ_03464	1121115.AXVN01000043_gene3383	1.62e-187	521.0	COG0300@1|root,COG0300@2|Bacteria,1UHN7@1239|Firmicutes,25FVQ@186801|Clostridia	186801|Clostridia	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
PKFBPKFJ_03465	1121115.AXVN01000043_gene3382	6.52e-86	252.0	COG2461@1|root,COG2461@2|Bacteria,1V9ZF@1239|Firmicutes,24F8Y@186801|Clostridia	186801|Clostridia	S	Hemerythrin HHE cation binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03466	1121115.AXVN01000043_gene3381	1.38e-57	181.0	2E53T@1|root,32ZWT@2|Bacteria,1VJS8@1239|Firmicutes,24S8H@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03467	457412.RSAG_02434	1.51e-297	812.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_03468	457412.RSAG_02433	2.4e-161	452.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03469	457412.RSAG_02432	0.0	904.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3WHZK@541000|Ruminococcaceae	186801|Clostridia	J	tRNA (Uracil-5-)-methyltransferase	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
PKFBPKFJ_03470	1121115.AXVN01000132_gene729	7.81e-29	104.0	2E4IR@1|root,32ZDT@2|Bacteria,1VENP@1239|Firmicutes,24NT8@186801|Clostridia,3Y0CG@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03471	1121115.AXVN01000132_gene730	5.05e-162	453.0	COG0546@1|root,COG0546@2|Bacteria,1UHUD@1239|Firmicutes,25E2T@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
PKFBPKFJ_03472	457412.RSAG_02429	0.0	1435.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3WGKX@541000|Ruminococcaceae	186801|Clostridia	L	ATP-dependent DNA helicase	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
PKFBPKFJ_03473	457412.RSAG_04538	4.35e-277	766.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24CRM@186801|Clostridia,3WS41@541000|Ruminococcaceae	186801|Clostridia	L	Transposase, IS605 OrfB family	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
PKFBPKFJ_03474	1235802.C823_04480	9.61e-66	207.0	COG3335@1|root,COG3335@2|Bacteria,1V3XY@1239|Firmicutes,24E1Y@186801|Clostridia	186801|Clostridia	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3
PKFBPKFJ_03475	742735.HMPREF9467_05205	2.31e-49	164.0	COG3415@1|root,COG3415@2|Bacteria,1VHRG@1239|Firmicutes,2501Q@186801|Clostridia	1239|Firmicutes	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_32
PKFBPKFJ_03476	471875.RUMLAC_01066	1.07e-210	593.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1UQRR@1239|Firmicutes,25DTG@186801|Clostridia,3WQRU@541000|Ruminococcaceae	1239|Firmicutes	L	COG COG3335 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_23,HTH_32
PKFBPKFJ_03478	1235802.C823_04890	3.49e-64	210.0	COG5433@1|root,COG5433@2|Bacteria,1V0JK@1239|Firmicutes,249XC@186801|Clostridia	186801|Clostridia	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PKFBPKFJ_03479	1235802.C823_04890	1.91e-106	320.0	COG5433@1|root,COG5433@2|Bacteria,1V0JK@1239|Firmicutes,249XC@186801|Clostridia	186801|Clostridia	L	PFAM Transposase, IS4-like	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
PKFBPKFJ_03480	1449050.JNLE01000003_gene3703	1.1e-40	139.0	COG3682@1|root,COG3682@2|Bacteria,1V4WY@1239|Firmicutes,25D48@186801|Clostridia,36U6Y@31979|Clostridiaceae	186801|Clostridia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
PKFBPKFJ_03481	1123075.AUDP01000034_gene2	1.7e-06	58.9	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,24A30@186801|Clostridia,3WJX1@541000|Ruminococcaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
PKFBPKFJ_03484	546269.HMPREF0389_00631	1.96e-29	105.0	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia,25RYI@186804|Peptostreptococcaceae	186801|Clostridia	S	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
PKFBPKFJ_03485	1232446.BAIE02000006_gene2113	7.1e-217	606.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,267WT@186813|unclassified Clostridiales	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase
PKFBPKFJ_03486	642492.Clole_1890	3.65e-18	91.3	COG3290@1|root,COG3290@2|Bacteria,1UZ9P@1239|Firmicutes,24MR7@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,SPOB_a
PKFBPKFJ_03489	658086.HMPREF0994_01669	9.24e-25	102.0	COG3279@1|root,COG3279@2|Bacteria,1VBY3@1239|Firmicutes,24GY2@186801|Clostridia,27K4B@186928|unclassified Lachnospiraceae	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_03491	1410653.JHVC01000016_gene333	1.82e-36	134.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,36DJG@31979|Clostridiaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_03492	537007.BLAHAN_06990	2.29e-12	63.5	2FA0G@1|root,3429J@2|Bacteria,1VXK8@1239|Firmicutes,24RRN@186801|Clostridia,3Y0WK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03493	1121115.AXVN01000007_gene3569	1.57e-137	389.0	COG2088@1|root,COG2088@2|Bacteria,1V19U@1239|Firmicutes,249EY@186801|Clostridia	186801|Clostridia	D	Belongs to the SpoVG family	-	-	-	-	-	-	-	-	-	-	-	-	SpoVG
PKFBPKFJ_03494	1121115.AXVN01000007_gene3568	1.23e-112	331.0	COG0553@1|root,COG0553@2|Bacteria,1TPQA@1239|Firmicutes,24EWN@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C
PKFBPKFJ_03495	1226325.HMPREF1548_01694	0.0	1190.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,36DU1@31979|Clostridiaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_03496	1226325.HMPREF1548_01693	1.95e-45	147.0	2C5R4@1|root,33UE0@2|Bacteria,1VUS0@1239|Firmicutes,25QAI@186801|Clostridia,36SYX@31979|Clostridiaceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PKFBPKFJ_03497	471875.RUMLAC_00937	3.67e-57	179.0	292IX@1|root,2ZQ2Y@2|Bacteria,1TV0U@1239|Firmicutes,258A6@186801|Clostridia,3WMAJ@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03498	471875.RUMLAC_00375	6.66e-39	129.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
PKFBPKFJ_03499	471875.RUMLAC_00374	5.49e-57	177.0	2C1NT@1|root,32JUU@2|Bacteria,1V7IC@1239|Firmicutes,24JFE@186801|Clostridia	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03500	658655.HMPREF0988_00007	8.06e-76	228.0	COG1396@1|root,COG1396@2|Bacteria,1VETP@1239|Firmicutes,25EH8@186801|Clostridia	186801|Clostridia	K	helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_03501	1226325.HMPREF1548_01690	3.71e-236	650.0	COG3598@1|root,COG3598@2|Bacteria,1UIBK@1239|Firmicutes,24K1Q@186801|Clostridia,36UQ1@31979|Clostridiaceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,Prim-Pol
PKFBPKFJ_03502	1226325.HMPREF1548_01689	9.7e-270	743.0	COG1196@1|root,COG1196@2|Bacteria,1UQCD@1239|Firmicutes,24AY9@186801|Clostridia,36FC6@31979|Clostridiaceae	186801|Clostridia	D	Plasmid recombination enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
PKFBPKFJ_03503	1226325.HMPREF1548_01688	5.82e-35	119.0	2FGY9@1|root,348TH@2|Bacteria,1W15E@1239|Firmicutes,24VBR@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
PKFBPKFJ_03504	457412.RSAG_03498	1e-290	793.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,24AH4@186801|Clostridia,3WGYW@541000|Ruminococcaceae	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
PKFBPKFJ_03505	1121115.AXVN01000131_gene736	0.0	1061.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,3Y0FH@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score 9.99	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
PKFBPKFJ_03506	457412.RSAG_02311	2.21e-228	627.0	COG2221@1|root,COG2221@2|Bacteria,1UI1A@1239|Firmicutes,25EAA@186801|Clostridia,3WSRT@541000|Ruminococcaceae	186801|Clostridia	C	Nitrite/Sulfite reductase ferredoxin-like half domain	dsvA	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C,Fer4,Fer4_10,NIR_SIR,NIR_SIR_ferr
PKFBPKFJ_03507	457412.RSAG_02312	1.71e-205	568.0	COG0583@1|root,COG0583@2|Bacteria,1TSNI@1239|Firmicutes,249QS@186801|Clostridia,3WIYC@541000|Ruminococcaceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_03508	1121115.AXVN01000064_gene4035	1.26e-121	346.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,3XZ0W@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
PKFBPKFJ_03509	1256908.HMPREF0373_01233	2.13e-111	320.0	COG4734@1|root,COG4734@2|Bacteria,1UX6H@1239|Firmicutes,24AM6@186801|Clostridia,25Y1G@186806|Eubacteriaceae	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
PKFBPKFJ_03510	1256908.HMPREF0373_01232	8.16e-67	202.0	2AJ8P@1|root,319TK@2|Bacteria,1V9F5@1239|Firmicutes,24KKK@186801|Clostridia,25Z6B@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03511	1292035.H476_1348	1.93e-90	271.0	COG4767@1|root,COG4767@2|Bacteria,1V82R@1239|Firmicutes,25BAW@186801|Clostridia,25TXK@186804|Peptostreptococcaceae	186801|Clostridia	V	VanZ like family	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
PKFBPKFJ_03512	445973.CLOBAR_01106	4.15e-42	138.0	2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,24N4I@186801|Clostridia,25TWP@186804|Peptostreptococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03513	1235790.C805_01420	2.36e-22	86.3	2E3NJ@1|root,32YKN@2|Bacteria,1VIHR@1239|Firmicutes,24SDK@186801|Clostridia,25Z8P@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3789)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3789
PKFBPKFJ_03514	411459.RUMOBE_02873	6.29e-292	796.0	COG2946@1|root,COG2946@2|Bacteria,1UHNT@1239|Firmicutes,24ZUP@186801|Clostridia,3XZ7X@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,Rep_trans
PKFBPKFJ_03515	742723.HMPREF9477_00865	0.0	933.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,27K03@186928|unclassified Lachnospiraceae	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,FtsK_SpoIIIE
PKFBPKFJ_03516	445973.CLOBAR_01110	4.76e-125	357.0	COG4709@1|root,COG4709@2|Bacteria,1V9EZ@1239|Firmicutes,24JU2@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1700)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
PKFBPKFJ_03517	445973.CLOBAR_01111	1.18e-76	228.0	COG1695@1|root,COG1695@2|Bacteria,1VA8U@1239|Firmicutes,24NA9@186801|Clostridia,25TEY@186804|Peptostreptococcaceae	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
PKFBPKFJ_03518	445973.CLOBAR_01112	6.06e-70	211.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,24IAF@186801|Clostridia,25RF1@186804|Peptostreptococcaceae	186801|Clostridia	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
PKFBPKFJ_03519	658655.HMPREF0988_03170	0.0	934.0	2CET6@1|root,2Z92J@2|Bacteria,1TQGV@1239|Firmicutes,24ARS@186801|Clostridia,27RTG@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03524	500632.CLONEX_03997	4.81e-65	199.0	2DJY1@1|root,307TR@2|Bacteria,1V50J@1239|Firmicutes,24I18@186801|Clostridia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PKFBPKFJ_03525	500632.CLONEX_03998	2.39e-238	658.0	COG3843@1|root,COG3843@2|Bacteria,1UZXP@1239|Firmicutes	1239|Firmicutes	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PKFBPKFJ_03526	1121333.JMLH01000011_gene668	2.88e-68	207.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,3VQB2@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Bacterial protein of unknown function (DUF961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
PKFBPKFJ_03527	1256908.HMPREF0373_00445	2.36e-65	200.0	COG1396@1|root,COG1396@2|Bacteria,1VEGA@1239|Firmicutes,25EHT@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_03528	742723.HMPREF9477_00865	0.0	921.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,27K03@186928|unclassified Lachnospiraceae	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	DUF87,FtsK_SpoIIIE
PKFBPKFJ_03529	411459.RUMOBE_02873	1.22e-289	790.0	COG2946@1|root,COG2946@2|Bacteria,1UHNT@1239|Firmicutes,24ZUP@186801|Clostridia,3XZ7X@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,HTH_31,Rep_trans
PKFBPKFJ_03530	658659.HMPREF0983_03987	2.29e-20	81.3	2E3NJ@1|root,32YKN@2|Bacteria,1VIHR@1239|Firmicutes,3VRKR@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Protein of unknown function (DUF3789)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3789
PKFBPKFJ_03531	1235790.C805_01419	8.37e-42	137.0	2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,24N4I@186801|Clostridia,25X23@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03532	1121333.JMLH01000011_gene661	5.22e-65	198.0	2ATI9@1|root,31J23@2|Bacteria,1V7YH@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03533	1121333.JMLH01000011_gene660	4.06e-118	337.0	COG4734@1|root,COG4734@2|Bacteria,1UX6H@1239|Firmicutes,3VPP6@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
PKFBPKFJ_03534	1121333.JMLH01000011_gene659	6.25e-122	347.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,3VPTE@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
PKFBPKFJ_03535	525254.HMPREF0072_1942	5.37e-138	392.0	COG1136@1|root,COG1136@2|Bacteria,1V3NN@1239|Firmicutes,24I94@186801|Clostridia,22HGS@1570339|Peptoniphilaceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03536	525254.HMPREF0072_1944	7.15e-232	655.0	COG4652@1|root,COG4652@2|Bacteria,1UYA7@1239|Firmicutes,250QA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03537	1449050.JNLE01000003_gene887	4.06e-35	123.0	2BE7G@1|root,327YF@2|Bacteria,1UTVH@1239|Firmicutes,254I3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03538	1235799.C818_02642	9.66e-134	380.0	COG1476@1|root,COG1476@2|Bacteria,1TRBW@1239|Firmicutes,24CX9@186801|Clostridia,27KKB@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_03540	1235799.C818_02643	8.73e-222	615.0	COG2946@1|root,COG2946@2|Bacteria,1UYFS@1239|Firmicutes,24FME@186801|Clostridia,27IW6@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Replication initiation factor	-	-	-	-	-	-	-	-	-	-	-	-	Rep_trans
PKFBPKFJ_03541	457412.RSAG_01334	6.9e-27	103.0	COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,248AA@186801|Clostridia,3WHIK@541000|Ruminococcaceae	186801|Clostridia	IQ	Oxidoreductase, short chain dehydrogenase reductase family protein	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
PKFBPKFJ_03542	1121115.AXVN01000097_gene3801	4.29e-85	250.0	COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,24J94@186801|Clostridia,3Y06G@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
PKFBPKFJ_03543	1121115.AXVN01000097_gene3800	4.98e-85	250.0	COG3304@1|root,COG3304@2|Bacteria,1VADH@1239|Firmicutes,24NFV@186801|Clostridia,3Y0CX@572511|Blautia	186801|Clostridia	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
PKFBPKFJ_03544	1121296.JONJ01000013_gene220	0.0	1361.0	COG1061@1|root,COG3886@1|root,COG1061@2|Bacteria,COG3886@2|Bacteria,1TQ62@1239|Firmicutes,249TK@186801|Clostridia,21XJ9@1506553|Lachnoclostridium	186801|Clostridia	L	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DUF3427,Helicase_C,PLDc_2,ResIII
PKFBPKFJ_03545	457412.RSAG_01329	2.75e-91	267.0	COG0494@1|root,COG0494@2|Bacteria,1V6ET@1239|Firmicutes,25EBI@186801|Clostridia,3WISB@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the Nudix hydrolase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
PKFBPKFJ_03546	457412.RSAG_01328	2.87e-47	151.0	2EIT0@1|root,33CIB@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03547	457412.RSAG_01326	1.48e-66	204.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia,3WJAK@541000|Ruminococcaceae	186801|Clostridia	T	low molecular weight	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
PKFBPKFJ_03548	411459.RUMOBE_01948	2.35e-49	167.0	2BFWX@1|root,329SF@2|Bacteria,1UGBJ@1239|Firmicutes,24TQN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03550	1410626.JHXB01000008_gene1187	1.69e-44	146.0	2CABA@1|root,32ZBQ@2|Bacteria,1VFWB@1239|Firmicutes,24RY5@186801|Clostridia,27Q1N@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03551	411459.RUMOBE_01951	3.73e-90	264.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,3Y01F@572511|Blautia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
PKFBPKFJ_03552	1121115.AXVN01000114_gene1667	2.18e-77	231.0	COG0346@1|root,COG0346@2|Bacteria,1V4DI@1239|Firmicutes,24I5W@186801|Clostridia,3Y052@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
PKFBPKFJ_03553	1121115.AXVN01000114_gene1668	1.4e-99	289.0	COG1671@1|root,COG1671@2|Bacteria,1TTTR@1239|Firmicutes,25NB2@186801|Clostridia,3Y1Q7@572511|Blautia	186801|Clostridia	S	Uncharacterized BCR, YaiI/YqxD family COG1671	-	-	-	-	-	-	-	-	-	-	-	-	DUF188
PKFBPKFJ_03554	1121115.AXVN01000114_gene1669	0.0	974.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,248FH@186801|Clostridia,3XZ9Z@572511|Blautia	186801|Clostridia	L	COG COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair	-	-	-	ko:K03502	-	-	-	-	ko00000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
PKFBPKFJ_03555	1121115.AXVN01000114_gene1670	1.46e-92	270.0	2DMPJ@1|root,32SWG@2|Bacteria,1V7RA@1239|Firmicutes,24NGU@186801|Clostridia,3Y0C1@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03556	457412.RSAG_01318	1.46e-106	307.0	2BFEN@1|root,32988@2|Bacteria,1V9U5@1239|Firmicutes,24JWC@186801|Clostridia,3WJIN@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4869)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4869
PKFBPKFJ_03557	457412.RSAG_01317	2.52e-237	652.0	28I6P@1|root,2Z89K@2|Bacteria,1TSZ7@1239|Firmicutes,24AUY@186801|Clostridia,3WHKG@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03559	1121115.AXVN01000114_gene1666	2.88e-13	67.0	COG0242@1|root,COG0242@2|Bacteria,1V73T@1239|Firmicutes,24FT0@186801|Clostridia,3Y01F@572511|Blautia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
PKFBPKFJ_03560	457412.RSAG_01316	5e-130	369.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,3WIA5@541000|Ruminococcaceae	186801|Clostridia	H	GTP cyclohydrolase I	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
PKFBPKFJ_03561	1121115.AXVN01000114_gene1672	7.91e-115	329.0	COG1418@1|root,COG1418@2|Bacteria,1VBWP@1239|Firmicutes,24JJV@186801|Clostridia,3Y06V@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
PKFBPKFJ_03562	457412.RSAG_01314	1.06e-193	537.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,3WHB5@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
PKFBPKFJ_03563	457412.RSAG_01313	1.16e-204	566.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,3WI4F@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
PKFBPKFJ_03564	1121115.AXVN01000114_gene1675	1.45e-76	228.0	COG1917@1|root,COG1917@2|Bacteria,1VGJQ@1239|Firmicutes,25EGC@186801|Clostridia,3Y09F@572511|Blautia	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
PKFBPKFJ_03565	1121115.AXVN01000114_gene1676	1.93e-305	832.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,3XYMU@572511|Blautia	186801|Clostridia	E	M18 family aminopeptidase	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
PKFBPKFJ_03566	457412.RSAG_01310	2.08e-200	554.0	COG0561@1|root,COG0561@2|Bacteria,1UFDJ@1239|Firmicutes,25B6S@186801|Clostridia,3WKHA@541000|Ruminococcaceae	186801|Clostridia	S	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
PKFBPKFJ_03567	457412.RSAG_01309	2.85e-216	598.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia,3WI18@541000|Ruminococcaceae	186801|Clostridia	S	Transporter, auxin efflux carrier (AEC) family protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
PKFBPKFJ_03568	457412.RSAG_04656	4.65e-256	701.0	COG2365@1|root,COG2365@2|Bacteria,1V639@1239|Firmicutes,25CGQ@186801|Clostridia	186801|Clostridia	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
PKFBPKFJ_03569	1121115.AXVN01000170_gene503	5.14e-111	319.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,3Y022@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
PKFBPKFJ_03570	1121115.AXVN01000170_gene502	9.63e-248	679.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3XYWE@572511|Blautia	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
PKFBPKFJ_03571	457412.RSAG_01304	5.47e-120	343.0	2C2RJ@1|root,33VFU@2|Bacteria,1VV8Z@1239|Firmicutes,250DV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03572	1121115.AXVN01000001_gene1176	5.14e-42	137.0	2FI33@1|root,349VV@2|Bacteria,1VYV4@1239|Firmicutes,253ZQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03573	1121115.AXVN01000001_gene1175	5.45e-78	236.0	COG3279@1|root,COG3279@2|Bacteria,1TSDB@1239|Firmicutes,24MQ4@186801|Clostridia,3Y2AV@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
PKFBPKFJ_03574	1121115.AXVN01000001_gene1174	3.77e-161	459.0	COG3290@1|root,COG3290@2|Bacteria,1TS6E@1239|Firmicutes,24DDI@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PKFBPKFJ_03575	457412.RSAG_01301	1.27e-87	268.0	COG3290@1|root,COG3290@2|Bacteria,1TS6E@1239|Firmicutes,24DDI@186801|Clostridia,3WS78@541000|Ruminococcaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
PKFBPKFJ_03576	457412.RSAG_01300	1.07e-150	423.0	COG2964@1|root,COG2964@2|Bacteria,1TSI2@1239|Firmicutes,249X6@186801|Clostridia,3WM7H@541000|Ruminococcaceae	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
PKFBPKFJ_03577	1121115.AXVN01000001_gene1172	0.0	916.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,3XZ6S@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
PKFBPKFJ_03578	1121115.AXVN01000001_gene1171	1.92e-141	399.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,3Y06N@572511|Blautia	186801|Clostridia	O	COG NOG13230 non supervised orthologous group	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
PKFBPKFJ_03579	457412.RSAG_01297	1.27e-273	750.0	COG1301@1|root,COG1301@2|Bacteria,1TP4N@1239|Firmicutes,2494N@186801|Clostridia,3WHRD@541000|Ruminococcaceae	186801|Clostridia	C	Sodium:dicarboxylate symporter family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
PKFBPKFJ_03580	457412.RSAG_01296	7.55e-241	661.0	COG1975@1|root,COG1975@2|Bacteria,1URM5@1239|Firmicutes,24AHV@186801|Clostridia	186801|Clostridia	O	XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
PKFBPKFJ_03581	1121115.AXVN01000001_gene1168	4.02e-76	231.0	COG3103@1|root,COG3103@2|Bacteria,1UHDJ@1239|Firmicutes,25Q4A@186801|Clostridia,3Y0IP@572511|Blautia	186801|Clostridia	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
PKFBPKFJ_03582	1121115.AXVN01000001_gene1167	1.46e-115	331.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,3XZVQ@572511|Blautia	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
PKFBPKFJ_03583	457412.RSAG_01292	2.14e-158	448.0	COG0652@1|root,COG0652@2|Bacteria,1V1SP@1239|Firmicutes,24G4H@186801|Clostridia,3WS4C@541000|Ruminococcaceae	186801|Clostridia	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
PKFBPKFJ_03584	1121115.AXVN01000001_gene1165	1.33e-135	383.0	COG2519@1|root,COG2519@2|Bacteria,1V6VU@1239|Firmicutes,24JEE@186801|Clostridia,3XZYS@572511|Blautia	186801|Clostridia	J	Putative rRNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
PKFBPKFJ_03585	1121115.AXVN01000001_gene1164	3.59e-284	777.0	COG0452@1|root,COG0452@2|Bacteria,1TPP3@1239|Firmicutes,247J3@186801|Clostridia,3XYIY@572511|Blautia	186801|Clostridia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
PKFBPKFJ_03586	457412.RSAG_01289	2.2e-174	487.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,3WHZV@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
PKFBPKFJ_03587	457412.RSAG_01288	6.01e-215	593.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,3WI75@541000|Ruminococcaceae	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
PKFBPKFJ_03588	457412.RSAG_01287	2.12e-308	842.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3WHZE@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_03589	1121115.AXVN01000001_gene1160	9.3e-272	744.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,3XYN5@572511|Blautia	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
PKFBPKFJ_03590	457412.RSAG_01285	2.05e-181	505.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,3WH3H@541000|Ruminococcaceae	186801|Clostridia	H	precorrin-4 C11-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
PKFBPKFJ_03591	457412.RSAG_01284	9.92e-265	725.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,3WHCR@541000|Ruminococcaceae	186801|Clostridia	H	Cobalamin synthesis G C-terminus	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
PKFBPKFJ_03592	457412.RSAG_01283	6.62e-175	487.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,3WHE5@541000|Ruminococcaceae	186801|Clostridia	H	Precorrin-3B	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
PKFBPKFJ_03593	1121115.AXVN01000001_gene1156	0.0	1328.0	COG2099@1|root,COG2241@1|root,COG2242@1|root,COG2099@2|Bacteria,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,3XYK0@572511|Blautia	186801|Clostridia	H	precorrin-6B methylase decarboxylase cbiT cbiE	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
PKFBPKFJ_03594	457412.RSAG_01281	0.0	946.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,3WH17@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
PKFBPKFJ_03595	457412.RSAG_01280	5.45e-231	636.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,3WGT1@541000|Ruminococcaceae	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
PKFBPKFJ_03596	457412.RSAG_01279	2.81e-260	712.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3WHN4@541000|Ruminococcaceae	186801|Clostridia	E	Psort location Cytoplasmic, score	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
PKFBPKFJ_03597	457412.RSAG_01278	0.0	976.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,3WHB7@541000|Ruminococcaceae	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
PKFBPKFJ_03598	1121115.AXVN01000001_gene1151	2.31e-147	415.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia,3XZ03@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
PKFBPKFJ_03599	457412.RSAG_01276	0.0	865.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,3WHQS@541000|Ruminococcaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
PKFBPKFJ_03600	457412.RSAG_01275	8.17e-208	574.0	COG2240@1|root,COG2240@2|Bacteria,1TRCR@1239|Firmicutes,24ABV@186801|Clostridia,3WGAX@541000|Ruminococcaceae	186801|Clostridia	H	Pyridoxal kinase	-	-	2.7.1.35	ko:K00868	ko00750,ko01100,map00750,map01100	-	R00174,R01909,R02493	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	Phos_pyr_kin
PKFBPKFJ_03601	457412.RSAG_01274	1.49e-114	329.0	COG4720@1|root,COG4720@2|Bacteria,1V8B5@1239|Firmicutes,24J8T@186801|Clostridia,3WJ8C@541000|Ruminococcaceae	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
PKFBPKFJ_03602	1121115.AXVN01000001_gene1147	3.47e-147	414.0	COG0731@1|root,COG0731@2|Bacteria,1UJ6S@1239|Firmicutes,25EWY@186801|Clostridia	186801|Clostridia	C	4Fe-4S single cluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_14,Radical_SAM
PKFBPKFJ_03603	457412.RSAG_01272	3.83e-61	187.0	COG0640@1|root,COG0640@2|Bacteria,1VA3M@1239|Firmicutes,24NEC@186801|Clostridia,3WKXH@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	czrA	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
PKFBPKFJ_03604	457412.RSAG_01271	2.16e-241	664.0	COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,24HIG@186801|Clostridia,3WMAG@541000|Ruminococcaceae	186801|Clostridia	S	SdpI/YhfL protein family	sdpI	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
PKFBPKFJ_03605	457412.RSAG_01270	4.15e-131	371.0	COG4636@1|root,COG4636@2|Bacteria,1VWXI@1239|Firmicutes,24ES8@186801|Clostridia,3WK7K@541000|Ruminococcaceae	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
PKFBPKFJ_03606	457412.RSAG_01269	2.42e-162	454.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,248JM@186801|Clostridia,3WHTF@541000|Ruminococcaceae	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03607	457412.RSAG_01268	1.68e-200	558.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24B3F@186801|Clostridia,3WRJK@541000|Ruminococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_03608	457412.RSAG_01267	5.01e-80	237.0	COG3682@1|root,COG3682@2|Bacteria,1V7DH@1239|Firmicutes,24JAQ@186801|Clostridia,3WK0J@541000|Ruminococcaceae	186801|Clostridia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
PKFBPKFJ_03609	457412.RSAG_01266	0.0	1050.0	COG4219@1|root,COG4219@2|Bacteria,1TQ0K@1239|Firmicutes,24AVI@186801|Clostridia,3WIKG@541000|Ruminococcaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
PKFBPKFJ_03610	457412.RSAG_01265	7.04e-107	307.0	COG1595@1|root,COG1595@2|Bacteria,1TSKU@1239|Firmicutes,24CQA@186801|Clostridia,3WJH9@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4
PKFBPKFJ_03611	1235798.C817_04251	2.45e-44	143.0	2DMV1@1|root,32TUT@2|Bacteria,1VDK0@1239|Firmicutes,24N5X@186801|Clostridia	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
PKFBPKFJ_03612	457412.RSAG_01262	3.11e-87	256.0	2C2YH@1|root,2ZBKZ@2|Bacteria,1V3N8@1239|Firmicutes,24FYJ@186801|Clostridia,3WIW7@541000|Ruminococcaceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PKFBPKFJ_03613	457412.RSAG_01261	0.0	1058.0	COG3843@1|root,COG3843@2|Bacteria,1TR9B@1239|Firmicutes,24A36@186801|Clostridia,3WH7V@541000|Ruminococcaceae	186801|Clostridia	U	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PKFBPKFJ_03614	457412.RSAG_01260	6.89e-180	500.0	COG3935@1|root,COG3935@2|Bacteria,1TQ65@1239|Firmicutes,249Q8@186801|Clostridia,3WHMR@541000|Ruminococcaceae	186801|Clostridia	L	Phage replisome organizer N-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_rep_org_N
PKFBPKFJ_03615	457412.RSAG_01259	1.47e-208	576.0	COG1484@1|root,COG1484@2|Bacteria,1TPZX@1239|Firmicutes,248F0@186801|Clostridia,3WG7N@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
PKFBPKFJ_03616	457412.RSAG_01258	6.81e-34	116.0	2CM6M@1|root,32SDU@2|Bacteria,1VCHU@1239|Firmicutes,24NMC@186801|Clostridia,3WK8X@541000|Ruminococcaceae	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
PKFBPKFJ_03617	457412.RSAG_01257	0.0	1060.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3WG90@541000|Ruminococcaceae	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
PKFBPKFJ_03618	457412.RSAG_01256	6.31e-159	446.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WG7X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03619	457412.RSAG_01255	0.0	1577.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3WH8W@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PKFBPKFJ_03620	457412.RSAG_01271	4.37e-241	663.0	COG5658@1|root,COG5658@2|Bacteria,1VBIT@1239|Firmicutes,24HIG@186801|Clostridia,3WMAG@541000|Ruminococcaceae	186801|Clostridia	S	SdpI/YhfL protein family	sdpI	-	-	-	-	-	-	-	-	-	-	-	DUF1648,SdpI
PKFBPKFJ_03621	457412.RSAG_01252	1.49e-307	840.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3WGPB@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
PKFBPKFJ_03622	457412.RSAG_01251	2.32e-152	428.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,3WGAG@541000|Ruminococcaceae	186801|Clostridia	C	system potassium uptake protein	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
PKFBPKFJ_03623	457412.RSAG_01250	0.0	976.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia,3WG8P@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	kdpD	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
PKFBPKFJ_03624	1121115.AXVN01000001_gene1141	6.61e-166	464.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,3XYRX@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03625	1121115.AXVN01000001_gene1140	4.83e-185	515.0	2DEAV@1|root,2ZM6Y@2|Bacteria,1V2HI@1239|Firmicutes,24GNN@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03626	1121115.AXVN01000001_gene1139	0.0	1133.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PKFBPKFJ_03627	1121115.AXVN01000001_gene1138	1.12e-293	802.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3XZQJ@572511|Blautia	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,NAD_binding_7,Shikimate_DH
PKFBPKFJ_03628	1121115.AXVN01000001_gene1137	1.04e-110	318.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,3Y08Y@572511|Blautia	186801|Clostridia	H	precorrin-2 oxidase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
PKFBPKFJ_03629	1121115.AXVN01000001_gene1136	1.16e-211	585.0	COG0181@1|root,COG0181@2|Bacteria,1TPFQ@1239|Firmicutes,2494Z@186801|Clostridia,3XYIS@572511|Blautia	186801|Clostridia	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	-	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
PKFBPKFJ_03630	1121115.AXVN01000001_gene1135	0.0	967.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,3XZE7@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
PKFBPKFJ_03631	457412.RSAG_01241	1.03e-236	650.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,3WGUW@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the ALAD family	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
PKFBPKFJ_03632	1121115.AXVN01000001_gene1133	1.54e-308	840.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3XZ92@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
PKFBPKFJ_03633	1121115.AXVN01000001_gene1132	2.96e-266	728.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,248JF@186801|Clostridia,3XZ28@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
PKFBPKFJ_03634	457412.RSAG_01238	9.11e-261	714.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3WG94@541000|Ruminococcaceae	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
PKFBPKFJ_03635	457412.RSAG_04660	1.45e-181	510.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia,3WGVT@541000|Ruminococcaceae	186801|Clostridia	P	Mg2 transporter protein CorA family protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
PKFBPKFJ_03636	1121115.AXVN01000001_gene1129	1.03e-207	574.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,3XYV8@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
PKFBPKFJ_03637	1121115.AXVN01000001_gene1128	0.0	882.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,3XZ9R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
PKFBPKFJ_03638	1121115.AXVN01000001_gene1127	2.92e-50	158.0	2FADH@1|root,342MV@2|Bacteria,1VXR1@1239|Firmicutes,252AC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03639	1121115.AXVN01000001_gene1126	0.0	939.0	COG0584@1|root,COG0584@2|Bacteria,1UVUW@1239|Firmicutes,25KN4@186801|Clostridia,3Y249@572511|Blautia	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
PKFBPKFJ_03640	457412.RSAG_01231	4.76e-196	550.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	FMN_bind,Flg_new,LRR_5
PKFBPKFJ_03642	1235798.C817_02113	2.63e-17	73.9	2EJDK@1|root,33D4M@2|Bacteria,1VPVH@1239|Firmicutes,24VVZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	RHH_5
PKFBPKFJ_03644	1121115.AXVN01000001_gene1125	6.38e-24	113.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	FMN_bind,Flg_new,LRR_5
PKFBPKFJ_03645	1232452.BAIB02000007_gene1603	1.2e-21	92.0	COG3617@1|root,COG3645@1|root,COG3617@2|Bacteria,COG3645@2|Bacteria,1TPKA@1239|Firmicutes,24BSZ@186801|Clostridia	186801|Clostridia	K	BRO family, N-terminal domain	-	-	-	ko:K07741	-	-	-	-	ko00000	-	-	-	ANT,Bro-N
PKFBPKFJ_03647	457412.RSAG_04642	1.09e-127	363.0	COG1595@1|root,COG1595@2|Bacteria,1V8A6@1239|Firmicutes,24CUW@186801|Clostridia,3WRUA@541000|Ruminococcaceae	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_03648	457412.RSAG_03060	6.72e-66	202.0	2EBCY@1|root,335DN@2|Bacteria,1VF9P@1239|Firmicutes,24KM6@186801|Clostridia,3WMHH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03649	457412.RSAG_04643	3.33e-153	429.0	COG2206@1|root,COG2206@2|Bacteria,1UKHX@1239|Firmicutes,25FXF@186801|Clostridia,3WP2X@541000|Ruminococcaceae	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03650	457412.RSAG_04644	2.07e-142	402.0	COG2339@1|root,COG2339@2|Bacteria,1V3JI@1239|Firmicutes,24AZQ@186801|Clostridia,3WIYQ@541000|Ruminococcaceae	186801|Clostridia	S	Protease prsW family	-	-	-	-	-	-	-	-	-	-	-	-	PrsW-protease
PKFBPKFJ_03651	457412.RSAG_03057	7.55e-69	208.0	2E82Y@1|root,332GY@2|Bacteria,1VEU7@1239|Firmicutes,24P37@186801|Clostridia,3WQMH@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03652	457412.RSAG_04645	0.0	1955.0	COG5263@1|root,COG5263@2|Bacteria,1VIRC@1239|Firmicutes	1239|Firmicutes	N	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03653	457412.RSAG_03054	5.94e-71	213.0	COG1106@1|root,COG1106@2|Bacteria,1TPJN@1239|Firmicutes,249WF@186801|Clostridia,3WIMF@541000|Ruminococcaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
PKFBPKFJ_03654	457412.RSAG_03053	3.23e-218	602.0	COG4823@1|root,COG4823@2|Bacteria,1UY67@1239|Firmicutes,24CBG@186801|Clostridia,3WK78@541000|Ruminococcaceae	186801|Clostridia	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
PKFBPKFJ_03657	1121115.AXVN01000098_gene2878	8.67e-299	814.0	COG2195@1|root,COG2195@2|Bacteria,1TP3A@1239|Firmicutes,248JJ@186801|Clostridia,3XZP1@572511|Blautia	186801|Clostridia	E	Cleaves the N-terminal amino acid of tripeptides	pepT	-	3.4.11.4	ko:K01258	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M42
PKFBPKFJ_03658	457412.RSAG_01933	5.59e-227	627.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,24AF9@186801|Clostridia,3WNDD@541000|Ruminococcaceae	186801|Clostridia	O	HflC and HflK could encode or regulate a protease	hflK	-	-	ko:K04088	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
PKFBPKFJ_03659	1121115.AXVN01000098_gene2880	4.43e-191	532.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	hflC	-	-	ko:K04087	-	M00742	-	-	ko00000,ko00002,ko01000	-	-	-	Band_7
PKFBPKFJ_03660	1121115.AXVN01000098_gene2881	1.24e-79	236.0	2DYSA@1|root,34AWR@2|Bacteria,1VZ6D@1239|Firmicutes,250AC@186801|Clostridia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
PKFBPKFJ_03661	457412.RSAG_01930	1.18e-99	289.0	2CV0R@1|root,32SWK@2|Bacteria,1VDAN@1239|Firmicutes,24K0G@186801|Clostridia	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
PKFBPKFJ_03662	1121115.AXVN01000098_gene2883	5.59e-45	145.0	COG5464@1|root,COG5464@2|Bacteria,1UHIM@1239|Firmicutes,25QA6@186801|Clostridia,3Y22B@572511|Blautia	186801|Clostridia	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03663	1121115.AXVN01000005_gene2235	0.0	1721.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia,3Y17B@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
PKFBPKFJ_03664	1256908.HMPREF0373_01458	9.77e-249	707.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25V53@186806|Eubacteriaceae	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
PKFBPKFJ_03666	457412.RSAG_00371	5.88e-132	374.0	COG4636@1|root,COG4636@2|Bacteria,1V1Q1@1239|Firmicutes,24ITV@186801|Clostridia,3WS1U@541000|Ruminococcaceae	1239|Firmicutes	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
PKFBPKFJ_03668	760192.Halhy_3075	2.48e-83	264.0	28NXW@1|root,2ZBV8@2|Bacteria	2|Bacteria	L	SacI restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	RE_SacI
PKFBPKFJ_03669	760192.Halhy_3076	8.37e-158	454.0	COG0270@1|root,COG0270@2|Bacteria,4NG9A@976|Bacteroidetes	976|Bacteroidetes	H	Cytosine-specific methyltransferase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
PKFBPKFJ_03671	742727.HMPREF9447_05508	9.79e-90	266.0	2BUDE@1|root,32PPB@2|Bacteria,4PAT1@976|Bacteroidetes,2FXPU@200643|Bacteroidia,4ATTI@815|Bacteroidaceae	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03672	742727.HMPREF9447_05507	1.59e-124	355.0	COG3646@1|root,COG3646@2|Bacteria,4P2N1@976|Bacteroidetes,2G3A9@200643|Bacteroidia,4AQIU@815|Bacteroidaceae	976|Bacteroidetes	S	ORF6N domain	-	-	-	-	-	-	-	-	-	-	-	-	ORF6N
PKFBPKFJ_03673	1121115.AXVN01000007_gene3564	0.0	2834.0	COG0553@1|root,COG0827@1|root,COG4646@1|root,COG0553@2|Bacteria,COG0827@2|Bacteria,COG4646@2|Bacteria	2|Bacteria	L	DNA restriction-modification system	XK27_00500	-	-	-	-	-	-	-	-	-	-	-	Eco57I,Helicase_C,N6_Mtase,ResIII,SNF2_N
PKFBPKFJ_03674	411461.DORFOR_03161	7.74e-111	328.0	COG0582@1|root,COG0582@2|Bacteria,1TSR6@1239|Firmicutes,249IV@186801|Clostridia,27WNF@189330|Dorea	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_03675	552398.HMPREF0866_02664	9.78e-68	215.0	COG0582@1|root,COG0582@2|Bacteria,1TSR6@1239|Firmicutes,249IV@186801|Clostridia,3WIB8@541000|Ruminococcaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_03676	1121115.AXVN01000144_gene2935	6.69e-47	150.0	2CBNB@1|root,32UW5@2|Bacteria,1VCKT@1239|Firmicutes,24N2B@186801|Clostridia,3Y1TY@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PKFBPKFJ_03678	1121115.AXVN01000144_gene2936	1.92e-201	557.0	2CH7H@1|root,2ZA4Z@2|Bacteria,1V0PM@1239|Firmicutes,24EPY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03679	1121115.AXVN01000144_gene2937	1.99e-125	358.0	28MGJ@1|root,2ZATS@2|Bacteria,1UY0K@1239|Firmicutes,24EII@186801|Clostridia,3XZU1@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03680	500632.CLONEX_02477	1.02e-260	715.0	28K2J@1|root,2Z9RW@2|Bacteria,1V000@1239|Firmicutes,24FF5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03681	1121115.AXVN01000144_gene2939	3.65e-15	71.6	2CFNE@1|root,2ZAY0@2|Bacteria,1UYUK@1239|Firmicutes,24FJT@186801|Clostridia,3Y04G@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03682	34740.HMEL003434-PA	8.73e-05	46.2	2E4T1@1|root,2SBN4@2759|Eukaryota,3ADG2@33154|Opisthokonta,3BWF0@33208|Metazoa,3DCTZ@33213|Bilateria	33208|Metazoa	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03683	1121115.AXVN01000063_gene718	6.13e-225	623.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,249JM@186801|Clostridia	186801|Clostridia	L	PFAM transposase, IS4 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
PKFBPKFJ_03684	457412.RSAG_04693	8.87e-39	129.0	COG3039@1|root,COG3039@2|Bacteria,1VGZ3@1239|Firmicutes,24X1X@186801|Clostridia	186801|Clostridia	L	COG3666 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
PKFBPKFJ_03685	457412.RSAG_00979	3.43e-81	240.0	COG1482@1|root,COG1482@2|Bacteria	2|Bacteria	G	cell wall glycoprotein biosynthetic process	-	-	5.3.1.8	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01819	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	PMI_typeI
PKFBPKFJ_03686	457412.RSAG_00980	1.03e-105	305.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
PKFBPKFJ_03687	457412.RSAG_00982	8.06e-92	268.0	COG0346@1|root,COG0346@2|Bacteria,1V6XU@1239|Firmicutes,24JFW@186801|Clostridia,3WK5Z@541000|Ruminococcaceae	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K08234	-	-	-	-	ko00000	-	-	-	Glyoxalase
PKFBPKFJ_03689	457412.RSAG_03491	6.96e-198	547.0	28J2Y@1|root,2Z8Z8@2|Bacteria,1V37E@1239|Firmicutes,24IHN@186801|Clostridia,3WN1K@541000|Ruminococcaceae	186801|Clostridia	S	Domain of unknown function (DUF4263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4263
PKFBPKFJ_03691	562743.JH976447_gene549	9.23e-230	635.0	COG3409@1|root,COG3409@2|Bacteria	2|Bacteria	M	Peptidoglycan-binding domain 1 protein	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Big_2,CHAP,PG_binding_1,Peptidase_M23,SH3_3
PKFBPKFJ_03693	1121115.AXVN01000199_gene606	4.94e-249	684.0	COG3177@1|root,COG3177@2|Bacteria,1TQMC@1239|Firmicutes,248JU@186801|Clostridia,3XYYW@572511|Blautia	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic
PKFBPKFJ_03694	518637.EUBIFOR_00726	6.13e-173	493.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,3VQ03@526524|Erysipelotrichia	526524|Erysipelotrichia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
PKFBPKFJ_03695	518637.EUBIFOR_00727	2.9e-228	629.0	29YMG@1|root,30KGY@2|Bacteria,1V4T3@1239|Firmicutes,3VR5D@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PKFBPKFJ_03696	518637.EUBIFOR_00728	3.77e-36	122.0	COG3311@1|root,COG3311@2|Bacteria,1V8AE@1239|Firmicutes,3VU5J@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PKFBPKFJ_03697	457412.RSAG_01691	3.59e-283	774.0	COG0526@1|root,COG0526@2|Bacteria,1TSFN@1239|Firmicutes,24DAS@186801|Clostridia	186801|Clostridia	CO	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
PKFBPKFJ_03698	1121115.AXVN01000014_gene1194	1.89e-32	112.0	2AQUU@1|root,31G2Z@2|Bacteria,1UDXX@1239|Firmicutes,25IS7@186801|Clostridia,3Y251@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03699	457412.RSAG_01689	8.8e-210	580.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3WI0F@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
PKFBPKFJ_03700	457412.RSAG_01688	1.55e-203	565.0	COG2207@1|root,COG2207@2|Bacteria,1V0IW@1239|Firmicutes,24BME@186801|Clostridia,3WM59@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
PKFBPKFJ_03701	457412.RSAG_01687	5.17e-129	367.0	2BXQ3@1|root,2ZCWE@2|Bacteria,1V3E8@1239|Firmicutes,24GTI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03702	457412.RSAG_01686	0.0	865.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia,3WMKQ@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
PKFBPKFJ_03703	457412.RSAG_01685	2.16e-208	577.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia,3WIYD@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport systems permease components	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
PKFBPKFJ_03704	457412.RSAG_01684	5.9e-194	538.0	COG0395@1|root,COG0395@2|Bacteria,1TSGI@1239|Firmicutes,24BDH@186801|Clostridia,3WJKJ@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
PKFBPKFJ_03705	457412.RSAG_01683	0.0	2007.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3WSRP@541000|Ruminococcaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HATPase_c,HisKA,PAS_4,Response_reg,SBP_bac_3
PKFBPKFJ_03706	1121115.AXVN01000014_gene1225	1.57e-298	815.0	COG1653@1|root,COG1653@2|Bacteria,1VR2M@1239|Firmicutes,24YJT@186801|Clostridia,3Y1T3@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
PKFBPKFJ_03707	1121115.AXVN01000014_gene1226	1.77e-184	515.0	COG1175@1|root,COG1175@2|Bacteria,1VT09@1239|Firmicutes,24YP4@186801|Clostridia,3Y1PN@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_03708	1235792.C808_04006	3.63e-138	397.0	COG0395@1|root,COG0395@2|Bacteria,1VQXI@1239|Firmicutes,24ECS@186801|Clostridia,27N2Y@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_03709	1121115.AXVN01000192_gene2633	0.0	981.0	COG3039@1|root,COG3039@2|Bacteria,1U377@1239|Firmicutes,24ASA@186801|Clostridia,3Y1AH@572511|Blautia	186801|Clostridia	L	COG NOG25267 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF772
PKFBPKFJ_03710	411483.FAEPRAA2165_00086	7.23e-106	317.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,3WHBQ@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03711	411483.FAEPRAA2165_00087	3.75e-65	211.0	COG1277@1|root,COG1277@2|Bacteria,1V2KB@1239|Firmicutes,25FR8@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
PKFBPKFJ_03712	742740.HMPREF9474_02911	3.47e-269	760.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,21YUA@1506553|Lachnoclostridium	186801|Clostridia	P	Cation transporter/ATPase, N-terminus	mgtA	-	3.6.3.2	ko:K01531	-	-	-	-	ko00000,ko01000	3.A.3.4	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
PKFBPKFJ_03713	1256908.HMPREF0373_00780	1.51e-15	75.9	COG1846@1|root,COG1846@2|Bacteria,1UYCZ@1239|Firmicutes,24C96@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03714	1121115.AXVN01000060_gene465	3.17e-181	506.0	COG1846@1|root,COG1846@2|Bacteria,1TZB3@1239|Firmicutes,25Q71@186801|Clostridia,3Y21V@572511|Blautia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03715	1121115.AXVN01000060_gene464	2.37e-15	73.9	28JTN@1|root,2Z9IV@2|Bacteria,1V2P2@1239|Firmicutes,24GDH@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03716	1121115.AXVN01000060_gene462	3.22e-43	150.0	COG2197@1|root,COG2197@2|Bacteria,1V1FA@1239|Firmicutes,25M6P@186801|Clostridia,3Y1FZ@572511|Blautia	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
PKFBPKFJ_03717	1121115.AXVN01000060_gene462	3.99e-132	380.0	COG2197@1|root,COG2197@2|Bacteria,1V1FA@1239|Firmicutes,25M6P@186801|Clostridia,3Y1FZ@572511|Blautia	186801|Clostridia	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
PKFBPKFJ_03718	1121115.AXVN01000034_gene3864	0.0	1082.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3XYMY@572511|Blautia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_5,Glycos_transf_1
PKFBPKFJ_03719	457412.RSAG_02494	3.73e-157	440.0	COG0500@1|root,COG2226@2|Bacteria,1UVT3@1239|Firmicutes,25B9E@186801|Clostridia,3WS52@541000|Ruminococcaceae	186801|Clostridia	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
PKFBPKFJ_03720	1121115.AXVN01000034_gene3866	2.91e-182	507.0	COG0596@1|root,COG0596@2|Bacteria,1TSU3@1239|Firmicutes,24DYW@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03721	1121115.AXVN01000034_gene3867	3.05e-45	153.0	COG3315@1|root,COG3315@2|Bacteria,1UPJI@1239|Firmicutes,24BUU@186801|Clostridia,3Y152@572511|Blautia	186801|Clostridia	Q	Leucine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	LCM
PKFBPKFJ_03722	1121115.AXVN01000034_gene3872	1.64e-149	420.0	COG1309@1|root,COG1309@2|Bacteria,1TT2J@1239|Firmicutes,24A5X@186801|Clostridia,3XZTU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
PKFBPKFJ_03723	1121115.AXVN01000034_gene3873	0.0	1110.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247VZ@186801|Clostridia,3XZ4W@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PKFBPKFJ_03724	1121115.AXVN01000034_gene3874	0.0	1087.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247PY@186801|Clostridia,3XZSV@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PKFBPKFJ_03725	457412.RSAG_02489	3.35e-63	205.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_03726	457412.RSAG_02489	1.11e-75	238.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
PKFBPKFJ_03727	457412.RSAG_02483	1.14e-48	155.0	2DN0F@1|root,32UQJ@2|Bacteria,1VBR6@1239|Firmicutes,24NWZ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
PKFBPKFJ_03728	457412.RSAG_02482	1.06e-110	318.0	28IR3@1|root,2Z8QN@2|Bacteria,1UKI8@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF3990)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791,DUF3990
PKFBPKFJ_03729	457412.RSAG_02481	8.17e-52	163.0	2EC32@1|root,33621@2|Bacteria,1VIVU@1239|Firmicutes,24Q0K@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3791
PKFBPKFJ_03730	457412.RSAG_00820	5.81e-27	102.0	COG4734@1|root,COG4734@2|Bacteria,1UZZ6@1239|Firmicutes,24DE1@186801|Clostridia	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
PKFBPKFJ_03731	478749.BRYFOR_06660	3.14e-73	226.0	COG1595@1|root,COG1595@2|Bacteria,1V1JW@1239|Firmicutes,24FYN@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_03732	1120998.AUFC01000041_gene550	1.76e-14	81.6	2DBN5@1|root,2ZA1Y@2|Bacteria,1UZYG@1239|Firmicutes,249F5@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
PKFBPKFJ_03734	592026.GCWU0000282_003279	4.5e-36	126.0	2C16E@1|root,2ZDCR@2|Bacteria,1W5KE@1239|Firmicutes,255D7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03736	1121115.AXVN01000034_gene3885	4e-293	801.0	COG5002@1|root,COG5002@2|Bacteria,1URKI@1239|Firmicutes,248WK@186801|Clostridia,3XZE3@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_03737	1121115.AXVN01000034_gene3886	1.98e-157	441.0	COG0745@1|root,COG0745@2|Bacteria,1UZIS@1239|Firmicutes,24CCE@186801|Clostridia,3XYX9@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03738	1121115.AXVN01000034_gene3887	0.0	1466.0	COG1653@1|root,COG1653@2|Bacteria,1V04I@1239|Firmicutes,247SU@186801|Clostridia,3XZJE@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
PKFBPKFJ_03739	1121115.AXVN01000034_gene3888	4.8e-224	617.0	COG1175@1|root,COG1175@2|Bacteria,1TQTC@1239|Firmicutes,24AQX@186801|Clostridia,3Y0K9@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
PKFBPKFJ_03740	1121115.AXVN01000034_gene3889	1.34e-200	556.0	COG0395@1|root,COG0395@2|Bacteria,1TS82@1239|Firmicutes,2488S@186801|Clostridia,3XYW1@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
PKFBPKFJ_03741	1121115.AXVN01000034_gene3890	2.64e-270	751.0	COG0845@1|root,COG0845@2|Bacteria,1V156@1239|Firmicutes,24E26@186801|Clostridia,3Y06F@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
PKFBPKFJ_03742	1121115.AXVN01000034_gene3891	1.26e-270	739.0	2BF19@1|root,328T3@2|Bacteria,1VAXF@1239|Firmicutes,258NW@186801|Clostridia,3Y0UJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03743	742765.HMPREF9457_03063	2.88e-136	387.0	2C1XQ@1|root,303QB@2|Bacteria,1V69G@1239|Firmicutes,24R2G@186801|Clostridia,27WTB@189330|Dorea	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
PKFBPKFJ_03744	1121115.AXVN01000034_gene3892	3.72e-202	560.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3Y11Y@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03745	742765.HMPREF9457_03065	1.83e-75	229.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,27WRX@189330|Dorea	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
PKFBPKFJ_03746	1504823.CCMM01000013_gene2509	1.19e-112	327.0	28P2J@1|root,2ZBYK@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3796)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3796
PKFBPKFJ_03747	1121333.JMLH01000011_gene666	8.83e-39	129.0	COG1476@1|root,COG1476@2|Bacteria,1TU8S@1239|Firmicutes,3VRXR@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_03748	1121115.AXVN01000034_gene3895	8.2e-210	579.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,3XYNB@572511|Blautia	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
PKFBPKFJ_03749	1121115.AXVN01000034_gene3896	3.93e-140	395.0	COG1674@1|root,COG1674@2|Bacteria,1TPHE@1239|Firmicutes,249WR@186801|Clostridia,3Y1AZ@572511|Blautia	186801|Clostridia	D	COG COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins	-	-	-	-	-	-	-	-	-	-	-	-	FtsK_SpoIIIE
PKFBPKFJ_03750	1121115.AXVN01000034_gene3897	1.04e-83	247.0	COG3620@1|root,COG3620@2|Bacteria,1TPHQ@1239|Firmicutes,249PB@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Rep_trans
PKFBPKFJ_03751	411459.RUMOBE_02495	3.09e-41	136.0	2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,24N4I@186801|Clostridia,3Y0EY@572511|Blautia	186801|Clostridia	S	COG NOG13238 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03752	1121115.AXVN01000034_gene3899	1.82e-65	199.0	COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,24JNU@186801|Clostridia,3Y0I5@572511|Blautia	186801|Clostridia	L	Addiction module antitoxin, RelB DinJ family	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
PKFBPKFJ_03753	1121115.AXVN01000034_gene3900	4.14e-72	216.0	COG3668@1|root,COG3668@2|Bacteria,1VD9X@1239|Firmicutes,24I2T@186801|Clostridia,3Y0R6@572511|Blautia	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K19092	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
PKFBPKFJ_03754	411459.RUMOBE_02496	2.67e-24	94.7	COG4734@1|root,COG4734@2|Bacteria,1UZZ6@1239|Firmicutes,257WT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
PKFBPKFJ_03755	1121115.AXVN01000034_gene3902	6.56e-131	371.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,3Y1DJ@572511|Blautia	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
PKFBPKFJ_03756	1121115.AXVN01000034_gene3903	1.33e-161	453.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia,3XYT6@572511|Blautia	186801|Clostridia	S	COG NOG08579 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
PKFBPKFJ_03757	665950.HMPREF1025_00452	8.76e-73	218.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia,27NDR@186928|unclassified Lachnospiraceae	186801|Clostridia	K	HxlR-like helix-turn-helix	hxlR	-	-	-	-	-	-	-	-	-	-	-	HxlR
PKFBPKFJ_03758	1121115.AXVN01000034_gene3904	1.07e-120	344.0	COG0778@1|root,COG0778@2|Bacteria,1V3YJ@1239|Firmicutes,24BKH@186801|Clostridia,3Y1HS@572511|Blautia	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
PKFBPKFJ_03759	1280698.AUJS01000083_gene3070	8.77e-140	407.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia	186801|Clostridia	L	Reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
PKFBPKFJ_03760	1121115.AXVN01000168_gene723	8.24e-248	679.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3Y1RC@572511|Blautia	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	xerD	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
PKFBPKFJ_03761	1121115.AXVN01000168_gene722	6e-245	671.0	COG0582@1|root,COG0582@2|Bacteria,1V2MU@1239|Firmicutes,25D5R@186801|Clostridia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PKFBPKFJ_03762	1121115.AXVN01000168_gene721	6.99e-307	835.0	COG4974@1|root,COG4974@2|Bacteria,1W02H@1239|Firmicutes,2547I@186801|Clostridia	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
PKFBPKFJ_03763	1280698.AUJS01000083_gene3070	3.72e-135	393.0	COG3344@1|root,COG3344@2|Bacteria,1TP9A@1239|Firmicutes,248M4@186801|Clostridia	186801|Clostridia	L	Reverse transcriptase	-	-	-	-	-	-	-	-	-	-	-	-	GIIM,RVT_1
PKFBPKFJ_03764	1121115.AXVN01000101_gene822	0.0	1648.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3XZ90@572511|Blautia	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
PKFBPKFJ_03765	1121115.AXVN01000101_gene821	1.44e-35	120.0	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia,3Y0SX@572511|Blautia	186801|Clostridia	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
PKFBPKFJ_03766	1121115.AXVN01000101_gene820	0.0	937.0	COG1055@1|root,COG1055@2|Bacteria,1TT1V@1239|Firmicutes,24ART@186801|Clostridia,3Y118@572511|Blautia	186801|Clostridia	P	Putative citrate transport	-	-	-	-	-	-	-	-	-	-	-	-	CitMHS_2
PKFBPKFJ_03767	1121115.AXVN01000101_gene819	1.07e-241	664.0	COG1102@1|root,COG1102@2|Bacteria,1TSIF@1239|Firmicutes,24BT4@186801|Clostridia,3Y132@572511|Blautia	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
PKFBPKFJ_03768	1121115.AXVN01000101_gene818	0.0	894.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3XYY1@572511|Blautia	186801|Clostridia	P	COG COG0733 Na -dependent transporters of the SNF family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
PKFBPKFJ_03769	1121115.AXVN01000101_gene817	1.1e-209	580.0	COG0583@1|root,COG0583@2|Bacteria,1TRYW@1239|Firmicutes,249AX@186801|Clostridia,3Y0AZ@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
PKFBPKFJ_03770	457412.RSAG_02473	1.51e-105	305.0	COG1846@1|root,COG1846@2|Bacteria,1VFS1@1239|Firmicutes,24QXV@186801|Clostridia,3WRVD@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
PKFBPKFJ_03771	1121115.AXVN01000101_gene815	0.0	1327.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XYTY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PKFBPKFJ_03772	457412.RSAG_02471	0.0	1167.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3WGVP@541000|Ruminococcaceae	186801|Clostridia	V	ABC-type multidrug transport system ATPase and permease	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
PKFBPKFJ_03773	1121115.AXVN01000051_gene792	0.0	1332.0	COG3973@1|root,COG3973@2|Bacteria,1TP39@1239|Firmicutes,249IG@186801|Clostridia,3XZ0C@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	helD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_19,UvrD-helicase,UvrD_C,UvrD_C_2
PKFBPKFJ_03774	1121115.AXVN01000051_gene793	1.15e-189	535.0	2EWK9@1|root,33PYD@2|Bacteria,1VTXK@1239|Firmicutes,24ZC9@186801|Clostridia,3Y0MZ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03775	457412.RSAG_02468	1.52e-198	549.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia,3WSIZ@541000|Ruminococcaceae	186801|Clostridia	S	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
PKFBPKFJ_03776	1121115.AXVN01000051_gene795	1.35e-203	564.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,3XYXT@572511|Blautia	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
PKFBPKFJ_03777	1121115.AXVN01000051_gene796	0.0	1284.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3XZ2F@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
PKFBPKFJ_03778	457412.RSAG_02464	1.72e-88	261.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia,3WK5R@541000|Ruminococcaceae	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03779	1121115.AXVN01000051_gene798	0.0	2191.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,3XYMT@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
PKFBPKFJ_03780	1121115.AXVN01000051_gene799	0.0	2393.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,3XYPU@572511|Blautia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
PKFBPKFJ_03781	457412.RSAG_02461	0.0	947.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,3WGN3@541000|Ruminococcaceae	186801|Clostridia	J	NOL1 NOP2 sun family	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
PKFBPKFJ_03782	1121115.AXVN01000051_gene801	2.25e-70	212.0	COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,24MRF@186801|Clostridia,3Y09J@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
PKFBPKFJ_03783	457412.RSAG_02459	1.22e-118	344.0	COG4709@1|root,COG4709@2|Bacteria,1VETQ@1239|Firmicutes,24G3G@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
PKFBPKFJ_03784	1121115.AXVN01000051_gene803	4.03e-140	405.0	2DN7I@1|root,32VZ1@2|Bacteria,1UJVJ@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
PKFBPKFJ_03785	1121115.AXVN01000051_gene804	6.14e-39	129.0	COG1983@1|root,COG1983@2|Bacteria,1VKBQ@1239|Firmicutes,24QU9@186801|Clostridia,3Y0IZ@572511|Blautia	186801|Clostridia	KT	PspC domain	pspC	-	-	-	-	-	-	-	-	-	-	-	PspC
PKFBPKFJ_03786	1121115.AXVN01000051_gene805	9.68e-36	121.0	2EIJI@1|root,33CAV@2|Bacteria,1VK5E@1239|Firmicutes,24MMQ@186801|Clostridia,3Y0TE@572511|Blautia	186801|Clostridia	S	COG NOG17864 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	SASP
PKFBPKFJ_03787	457412.RSAG_02455	4.82e-228	628.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia,3WI38@541000|Ruminococcaceae	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
PKFBPKFJ_03788	457412.RSAG_02454	7.07e-97	282.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia	186801|Clostridia	I	CoA-substrate-specific enzyme activase	hgdC	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
PKFBPKFJ_03789	1121115.AXVN01000057_gene2514	6.65e-217	606.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
PKFBPKFJ_03790	457412.RSAG_02452	0.0	1142.0	2DUPK@1|root,33RK6@2|Bacteria,1VRQV@1239|Firmicutes,24YX7@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03791	1121115.AXVN01000051_gene807	1.92e-37	140.0	COG1470@1|root,COG1470@2|Bacteria	2|Bacteria	S	cell adhesion involved in biofilm formation	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,DUF4384,TonB_dep_Rec
PKFBPKFJ_03792	457412.RSAG_02450	0.0	1098.0	COG4733@1|root,COG5492@1|root,COG4733@2|Bacteria,COG5492@2|Bacteria	2|Bacteria	N	domain, Protein	-	-	4.2.2.5	ko:K19049	-	-	-	-	ko00000,ko01000	-	PL8	-	Beta_helix,Big_2,Big_5,LRR_5,Lyase_8,SLH,VWA
PKFBPKFJ_03793	457412.RSAG_02449	1.31e-102	296.0	COG3385@1|root,COG3385@2|Bacteria,1VPWS@1239|Firmicutes,24V8I@186801|Clostridia	186801|Clostridia	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03794	457412.RSAG_02448	0.0	1058.0	COG4886@1|root,COG4886@2|Bacteria	2|Bacteria	S	regulation of response to stimulus	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
PKFBPKFJ_03795	1121115.AXVN01000102_gene3594	1.14e-164	460.0	COG0745@1|root,COG0745@2|Bacteria,1TSCM@1239|Firmicutes,248K7@186801|Clostridia	186801|Clostridia	K	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03796	1121115.AXVN01000102_gene3595	1.11e-41	136.0	COG2909@1|root,COG2909@2|Bacteria,1VGAF@1239|Firmicutes,24SMP@186801|Clostridia	186801|Clostridia	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
PKFBPKFJ_03797	1121115.AXVN01000102_gene3596	4.76e-84	248.0	COG1396@1|root,COG1396@2|Bacteria,1V331@1239|Firmicutes,24G00@186801|Clostridia,3Y0TY@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
PKFBPKFJ_03798	411902.CLOBOL_04257	1.52e-67	204.0	2E6DS@1|root,333AA@2|Bacteria,1VGCH@1239|Firmicutes,24N8Z@186801|Clostridia,221BI@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03799	1121115.AXVN01000102_gene3598	6.81e-82	242.0	2C5R4@1|root,30EV5@2|Bacteria,1V4TD@1239|Firmicutes,25CQK@186801|Clostridia	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PKFBPKFJ_03800	1121115.AXVN01000102_gene3599	4.13e-240	662.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XYWF@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,T4SS-DNA_transf,Zn_ribbon_recom
PKFBPKFJ_03801	411902.CLOBOL_04254	7.88e-35	122.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia,21XRZ@1506553|Lachnoclostridium	186801|Clostridia	U	COG COG3505 Type IV secretory pathway, VirD4 components	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
PKFBPKFJ_03802	457412.RSAG_02023	6.15e-65	205.0	COG0642@1|root,COG2205@2|Bacteria,1TXC7@1239|Firmicutes,2492E@186801|Clostridia,3WHRJ@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_03803	1232443.BAIA02000032_gene1910	1.32e-218	603.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,268B9@186813|unclassified Clostridiales	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K19309	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC_tran
PKFBPKFJ_03804	457412.RSAG_02021	4.75e-174	487.0	COG1668@1|root,COG1668@2|Bacteria,1V48D@1239|Firmicutes,24F46@186801|Clostridia,3WRRQ@541000|Ruminococcaceae	186801|Clostridia	CP	ABC-2 family transporter protein	-	-	-	ko:K19310	ko02010,map02010	M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.131.1	-	-	ABC2_membrane_4
PKFBPKFJ_03805	457412.RSAG_02020	1.86e-179	501.0	COG4200@1|root,COG4200@2|Bacteria,1TSZG@1239|Firmicutes,25DDS@186801|Clostridia,3WSGF@541000|Ruminococcaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K19310	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC2_membrane_4
PKFBPKFJ_03806	457412.RSAG_02019	5.66e-106	306.0	28PS7@1|root,2ZCDT@2|Bacteria,1V252@1239|Firmicutes,24GY8@186801|Clostridia,3WJI3@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03807	457412.RSAG_04586	6.57e-21	82.4	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
PKFBPKFJ_03808	1121115.AXVN01000102_gene3593	4.51e-191	532.0	COG0642@1|root,COG2205@2|Bacteria,1TXC7@1239|Firmicutes,2492E@186801|Clostridia,3Y2AT@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_03809	1121115.AXVN01000102_gene3592	1.19e-217	601.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,3XYU3@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K19309	ko02010,map02010	M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.131.1	-	-	ABC_tran
PKFBPKFJ_03810	1121115.AXVN01000102_gene3591	1.17e-174	488.0	COG1668@1|root,COG1668@2|Bacteria,1V48D@1239|Firmicutes,24F46@186801|Clostridia,3Y2BE@572511|Blautia	186801|Clostridia	CP	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_4
PKFBPKFJ_03811	1121115.AXVN01000102_gene3590	6.07e-185	515.0	COG4200@1|root,COG4200@2|Bacteria,1TSZG@1239|Firmicutes,25DDS@186801|Clostridia,3Y27U@572511|Blautia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K19310	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC2_membrane_4
PKFBPKFJ_03812	742735.HMPREF9467_04940	4.3e-101	293.0	28PS7@1|root,2ZCDT@2|Bacteria,1V252@1239|Firmicutes,24GY8@186801|Clostridia,22043@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03813	1280671.AUJH01000028_gene895	1.02e-25	97.8	2CU1H@1|root,32SUI@2|Bacteria,1VB8S@1239|Firmicutes,24PZC@186801|Clostridia,4C0G3@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03814	742765.HMPREF9457_01634	5.05e-216	599.0	COG1266@1|root,COG1266@2|Bacteria,1UYS2@1239|Firmicutes,24BKW@186801|Clostridia,27X9E@189330|Dorea	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
PKFBPKFJ_03815	1519439.JPJG01000022_gene552	2.77e-42	144.0	COG1396@1|root,COG1396@2|Bacteria,1UM3W@1239|Firmicutes,25GA1@186801|Clostridia	186801|Clostridia	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
PKFBPKFJ_03816	1235799.C818_03007	1.23e-21	86.7	2DCK0@1|root,2ZEG2@2|Bacteria,1W2D4@1239|Firmicutes,255S2@186801|Clostridia,27SV0@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03817	457412.RSAG_02982	2.41e-111	319.0	2AJD7@1|root,319YQ@2|Bacteria,1V83F@1239|Firmicutes,24FWU@186801|Clostridia,3WP2T@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03819	519441.Smon_1511	4.33e-106	333.0	COG3677@1|root,COG3677@2|Bacteria,37BW6@32066|Fusobacteria	32066|Fusobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03820	457412.RSAG_02589	1.07e-193	541.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3WGP1@541000|Ruminococcaceae	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
PKFBPKFJ_03821	445973.CLOBAR_01114	0.0	1877.0	COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia,25T2H@186804|Peptostreptococcaceae	186801|Clostridia	M	Cna protein B-type domain	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
PKFBPKFJ_03822	457412.RSAG_03494	6.73e-207	571.0	COG4974@1|root,COG4974@2|Bacteria,1TR57@1239|Firmicutes,24ACW@186801|Clostridia,3WNBT@541000|Ruminococcaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
PKFBPKFJ_03823	457412.RSAG_03493	3.7e-306	832.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,3WQ1J@541000|Ruminococcaceae	186801|Clostridia	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
PKFBPKFJ_03824	457412.RSAG_04551	4.18e-13	62.0	2C4ZB@1|root,2ZGK7@2|Bacteria,1W22R@1239|Firmicutes,2561H@186801|Clostridia	457412.RSAG_04551|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03825	34506.g1440	7.32e-189	526.0	2D4BE@1|root,2SUJP@2759|Eukaryota,39GY5@33154|Opisthokonta,3CKSI@33208|Metazoa,3E2D0@33213|Bilateria,40Q1N@6231|Nematoda,1M7J2@119089|Chromadorea,4166C@6236|Rhabditida	33208|Metazoa	S	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PKFBPKFJ_03827	155864.EDL933_4863	2.42e-28	103.0	2E4DS@1|root,32Z93@2|Bacteria,1N93Z@1224|Proteobacteria,1SD4V@1236|Gammaproteobacteria,3XQ0F@561|Escherichia	1236|Gammaproteobacteria	S	response to butan-1-ol	yibT	GO:0001101,GO:0008150,GO:0010033,GO:0042221,GO:0050896,GO:0097305,GO:1901422,GO:1901700	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03829	1235790.C805_02649	0.0	1221.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
PKFBPKFJ_03830	1203606.HMPREF1526_01102	4.74e-139	395.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,36EH8@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03831	411463.EUBVEN_00958	0.0	1423.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,25VI3@186806|Eubacteriaceae	186801|Clostridia	MV	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
PKFBPKFJ_03832	1121115.AXVN01000007_gene3529	3.49e-227	628.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,3XYUP@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_03833	1121115.AXVN01000007_gene3528	1.08e-161	453.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,249PK@186801|Clostridia,3XZT3@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03834	1235798.C817_00081	2.16e-306	865.0	COG0577@1|root,COG0577@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
PKFBPKFJ_03835	97139.C824_05876	0.0	1036.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,36WRV@31979|Clostridiaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
PKFBPKFJ_03836	1235798.C817_00077	7.43e-152	427.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,27W9B@189330|Dorea	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03837	180332.JTGN01000009_gene4232	4.8e-139	435.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
PKFBPKFJ_03838	1235798.C817_00075	3.98e-29	104.0	2EBUS@1|root,30H5C@2|Bacteria,1UH5A@1239|Firmicutes,25PTW@186801|Clostridia,27X6U@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03839	1121115.AXVN01000007_gene3524	0.0	1469.0	COG0577@1|root,COG0577@2|Bacteria,1V0HA@1239|Firmicutes,24AID@186801|Clostridia,3XYH2@572511|Blautia	186801|Clostridia	V	COG COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
PKFBPKFJ_03840	1121115.AXVN01000007_gene3523	3.9e-150	423.0	COG1136@1|root,COG1136@2|Bacteria,1TQP5@1239|Firmicutes,24XTT@186801|Clostridia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PKFBPKFJ_03841	1121115.AXVN01000007_gene3522	4.59e-227	627.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,3XZPD@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_03842	1235798.C817_00073	1.74e-154	434.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,24FGF@186801|Clostridia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03843	1235790.C805_01979	0.0	956.0	COG0507@1|root,COG0507@2|Bacteria,1TR2Y@1239|Firmicutes,24B2Q@186801|Clostridia,25WMI@186806|Eubacteriaceae	186801|Clostridia	L	Uncharacterized conserved protein (DUF2075)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2075
PKFBPKFJ_03844	1232453.BAIF02000044_gene3502	1.52e-73	221.0	COG2315@1|root,COG2315@2|Bacteria,1VBCB@1239|Firmicutes,24MVS@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
PKFBPKFJ_03845	1232453.BAIF02000044_gene3501	7.09e-283	788.0	COG0741@1|root,COG0741@2|Bacteria,1V3F0@1239|Firmicutes,249C4@186801|Clostridia,26ADA@186813|unclassified Clostridiales	186801|Clostridia	M	CHAP domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAP,Lysozyme_like
PKFBPKFJ_03846	1232453.BAIF02000044_gene3500	1.03e-77	231.0	29TJA@1|root,30ESK@2|Bacteria,1V5K7@1239|Firmicutes,24HUK@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03847	1232453.BAIF02000044_gene3499	2e-137	394.0	28N5R@1|root,2ZBAW@2|Bacteria,1UZ09@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03848	665950.HMPREF1025_00578	0.0	1493.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,27IV0@186928|unclassified Lachnospiraceae	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
PKFBPKFJ_03849	1232453.BAIF02000044_gene3497	1.26e-96	281.0	COG3451@1|root,COG3451@2|Bacteria,1V6F7@1239|Firmicutes,24JKK@186801|Clostridia,2693R@186813|unclassified Clostridiales	186801|Clostridia	U	PrgI family protein	-	-	-	-	-	-	-	-	-	-	-	-	PrgI
PKFBPKFJ_03850	1232453.BAIF02000044_gene3496	1.71e-95	280.0	28NFE@1|root,2ZBHQ@2|Bacteria,1UFEH@1239|Firmicutes,24E0F@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4313)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4313
PKFBPKFJ_03851	1232453.BAIF02000044_gene3495	2.47e-188	524.0	2DB6V@1|root,2Z7IJ@2|Bacteria,1TRNS@1239|Firmicutes,24ANE@186801|Clostridia,267YD@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TrbL
PKFBPKFJ_03852	1232453.BAIF02000044_gene3494	4.61e-74	223.0	2DMPF@1|root,32SVU@2|Bacteria,1VA0M@1239|Firmicutes,24JF3@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03853	1232453.BAIF02000044_gene3493	5.15e-169	485.0	COG3505@1|root,COG3505@2|Bacteria,1TPCF@1239|Firmicutes,2489C@186801|Clostridia	186801|Clostridia	U	COG COG3505 Type IV secretory pathway, VirD4 components	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf,TraG-D_C
PKFBPKFJ_03854	1297617.JPJD01000080_gene1397	8.94e-28	100.0	2E8ED@1|root,332SU@2|Bacteria,1VJ6A@1239|Firmicutes,24SJK@186801|Clostridia,26BRY@186813|unclassified Clostridiales	186801|Clostridia	S	Transposon-encoded protein TnpW	-	-	-	-	-	-	-	-	-	-	-	-	TnpW
PKFBPKFJ_03855	1203606.HMPREF1526_01061	0.0	1215.0	COG0358@1|root,COG3598@1|root,COG0358@2|Bacteria,COG3598@2|Bacteria,1TQKP@1239|Firmicutes,247WJ@186801|Clostridia,36FQT@31979|Clostridiaceae	186801|Clostridia	L	Protein of unknown function (DUF3991)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,DUF3991,Toprim_2
PKFBPKFJ_03856	445972.ANACOL_03092	3.55e-71	213.0	29VEW@1|root,30GW0@2|Bacteria,1V45S@1239|Firmicutes,24J1C@186801|Clostridia,3WPIR@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03857	445972.ANACOL_03091	0.0	984.0	COG1196@1|root,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,3WIAK@541000|Ruminococcaceae	186801|Clostridia	D	MobA MobL family protein	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
PKFBPKFJ_03858	411462.DORLON_00196	3.51e-73	221.0	292P2@1|root,2ZQ6W@2|Bacteria,1V4YF@1239|Firmicutes,24I6C@186801|Clostridia,27WS7@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3847
PKFBPKFJ_03859	1226322.HMPREF1545_00002	1.2e-134	382.0	COG1136@1|root,COG1136@2|Bacteria,1V3NN@1239|Firmicutes,24I94@186801|Clostridia,2N8G1@216572|Oscillospiraceae	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03860	411462.DORLON_00194	0.0	1232.0	COG4652@1|root,COG4652@2|Bacteria,1U507@1239|Firmicutes,249H3@186801|Clostridia,27WFW@189330|Dorea	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1430
PKFBPKFJ_03861	411462.DORLON_00193	6.47e-76	226.0	2C5R4@1|root,30S72@2|Bacteria,1V578@1239|Firmicutes,24IJT@186801|Clostridia,27WRP@189330|Dorea	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
PKFBPKFJ_03862	411462.DORLON_00192	0.0	1694.0	COG1961@1|root,COG3505@1|root,COG1961@2|Bacteria,COG3505@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27WCR@189330|Dorea	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,T4SS-DNA_transf,Zn_ribbon_recom
PKFBPKFJ_03863	658655.HMPREF0988_02893	3.08e-57	177.0	2DF5S@1|root,32U4Q@2|Bacteria,1UXVX@1239|Firmicutes,24P2A@186801|Clostridia,27Q0X@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4314
PKFBPKFJ_03864	1232453.BAIF02000044_gene3491	6.35e-64	196.0	2A3YK@1|root,30SH0@2|Bacteria,1V4XP@1239|Firmicutes,24HD3@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03865	411460.RUMTOR_00114	1.52e-212	588.0	COG4227@1|root,COG4227@2|Bacteria,1TSE0@1239|Firmicutes,24DYI@186801|Clostridia,3Y10X@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03866	1232453.BAIF02000044_gene3489	1.1e-134	387.0	295P2@1|root,2Z92B@2|Bacteria,1UPY6@1239|Firmicutes,25HRI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3801
PKFBPKFJ_03867	1232453.BAIF02000044_gene3488	9.47e-282	773.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,248VT@186801|Clostridia,26AAT@186813|unclassified Clostridiales	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PKFBPKFJ_03868	658655.HMPREF0988_02898	9e-66	200.0	2CDK1@1|root,32BE1@2|Bacteria,1V94B@1239|Firmicutes,25HVC@186801|Clostridia,27NBD@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PKFBPKFJ_03869	411460.RUMTOR_00110	1.09e-69	213.0	2C53N@1|root,33W6F@2|Bacteria,1VW3C@1239|Firmicutes,251AF@186801|Clostridia,3Y24W@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03870	1280698.AUJS01000059_gene785	3.62e-72	217.0	29606@1|root,304A9@2|Bacteria,1V4CV@1239|Firmicutes,24IR2@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03871	1280698.AUJS01000059_gene784	1.7e-202	559.0	COG0863@1|root,COG0863@2|Bacteria,1TRDZ@1239|Firmicutes,249ZT@186801|Clostridia,27WCZ@189330|Dorea	186801|Clostridia	L	DNA methylase	-	-	2.1.1.72	ko:K00571	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
PKFBPKFJ_03874	658655.HMPREF0988_02904	5.89e-111	327.0	28JA2@1|root,2Z94Y@2|Bacteria,1V0D4@1239|Firmicutes,24G1C@186801|Clostridia,27Q9G@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4314)	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03875	411470.RUMGNA_00487	1.65e-240	660.0	COG0358@1|root,COG0358@2|Bacteria,1UYNQ@1239|Firmicutes,25C9A@186801|Clostridia,3Y1H6@572511|Blautia	186801|Clostridia	L	Protein of unknown function (DUF3991)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3991,Toprim_2
PKFBPKFJ_03876	411470.RUMGNA_00488	8.32e-275	752.0	COG0192@1|root,COG0192@2|Bacteria,1TQ0Q@1239|Firmicutes,249X7@186801|Clostridia,3Y14I@572511|Blautia	186801|Clostridia	H	S-adenosylmethionine synthetase, C-terminal domain	metK3	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
PKFBPKFJ_03877	1235798.C817_03989	2.88e-63	194.0	COG3668@1|root,COG3668@2|Bacteria,1VD9X@1239|Firmicutes,24K2R@186801|Clostridia,27WUY@189330|Dorea	186801|Clostridia	S	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	-	-	-	-	-	-	-	-	-	ParE_toxin
PKFBPKFJ_03878	1235798.C817_03990	2.51e-62	191.0	COG3077@1|root,COG3077@2|Bacteria,1VGJW@1239|Firmicutes,24JNU@186801|Clostridia,27VWE@189330|Dorea	186801|Clostridia	L	RelB antitoxin	-	-	-	ko:K07473	-	-	-	-	ko00000,ko02048	-	-	-	RelB
PKFBPKFJ_03879	411470.RUMGNA_00494	5.24e-187	520.0	COG4509@1|root,COG4509@2|Bacteria,1V768@1239|Firmicutes,24A4B@186801|Clostridia,3XZVJ@572511|Blautia	186801|Clostridia	S	sortase, SrtB family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
PKFBPKFJ_03880	411470.RUMGNA_00495	0.0	2741.0	COG4932@1|root,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,2492K@186801|Clostridia,3XZ4G@572511|Blautia	186801|Clostridia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03881	411470.RUMGNA_00496	1.12e-114	328.0	COG2105@1|root,COG2105@2|Bacteria,1VDAD@1239|Firmicutes,24HW1@186801|Clostridia,3Y0DS@572511|Blautia	186801|Clostridia	S	COG NOG17855 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
PKFBPKFJ_03882	1280698.AUJS01000059_gene776	1.69e-231	637.0	28HR1@1|root,2Z7YI@2|Bacteria,1TRNR@1239|Firmicutes,2486X@186801|Clostridia,27UVH@189330|Dorea	186801|Clostridia	S	Putative amidoligase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Amidoligase_2
PKFBPKFJ_03883	411470.RUMGNA_00499	0.0	907.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,3XZQK@572511|Blautia	186801|Clostridia	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
PKFBPKFJ_03884	411470.RUMGNA_00501	3.47e-73	226.0	2DKWP@1|root,30MQ3@2|Bacteria,1V68I@1239|Firmicutes,25AX0@186801|Clostridia,3Y0NC@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03885	411470.RUMGNA_00502	7.33e-51	161.0	2EA91@1|root,334DG@2|Bacteria,1VER1@1239|Firmicutes,24SBA@186801|Clostridia,3Y26J@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03886	411470.RUMGNA_00503	6.98e-211	583.0	2DBA0@1|root,2Z80J@2|Bacteria,1TQY3@1239|Firmicutes,24B0S@186801|Clostridia,3XYSU@572511|Blautia	186801|Clostridia	S	StbA protein	-	-	-	ko:K18640	-	-	-	-	ko00000,ko04812	-	-	-	StbA
PKFBPKFJ_03887	411470.RUMGNA_00504	1.27e-65	200.0	2BF9M@1|root,3292H@2|Bacteria,1V8EC@1239|Firmicutes,24KY6@186801|Clostridia,3Y1XI@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03888	411470.RUMGNA_00505	1.74e-92	270.0	2B903@1|root,30GCT@2|Bacteria,1UFRQ@1239|Firmicutes,25MJG@186801|Clostridia,3Y1UK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03889	411470.RUMGNA_00506	1.33e-47	152.0	COG1396@1|root,COG1396@2|Bacteria,1VM7U@1239|Firmicutes,24UJF@186801|Clostridia,3Y0N2@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
PKFBPKFJ_03890	411470.RUMGNA_00507	3.92e-50	159.0	COG1396@1|root,COG1396@2|Bacteria,1VDA0@1239|Firmicutes,24PY4@186801|Clostridia,3Y0GH@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PKFBPKFJ_03891	500632.CLONEX_03810	3.23e-69	209.0	2F4GU@1|root,33X6S@2|Bacteria,1VWIU@1239|Firmicutes,251AG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03892	1235835.C814_02686	1.74e-111	323.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3WG7X@541000|Ruminococcaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03893	1235835.C814_02685	3.81e-211	586.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,3WI2K@541000|Ruminococcaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_03894	478749.BRYFOR_06528	4.66e-164	459.0	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,249PK@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03895	1235835.C814_02683	1.37e-83	246.0	COG1396@1|root,COG1396@2|Bacteria,1V331@1239|Firmicutes,24G00@186801|Clostridia,3WJJ9@541000|Ruminococcaceae	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PKFBPKFJ_03896	476272.RUMHYD_01305	1.35e-73	221.0	296J0@1|root,2ZTUJ@2|Bacteria,1V3IP@1239|Firmicutes,24H9K@186801|Clostridia,3Y0FW@572511|Blautia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PKFBPKFJ_03897	1235835.C814_02681	5.84e-306	836.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,3WH5V@541000|Ruminococcaceae	186801|Clostridia	U	Relaxase mobilization nuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
PKFBPKFJ_03898	1235798.C817_03947	3.04e-143	410.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,24AD8@186801|Clostridia,27WSX@189330|Dorea	186801|Clostridia	K	helix_turn_helix, mercury resistance	mta	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase,MerR_1,TipAS
PKFBPKFJ_03899	742741.HMPREF9475_02736	9.99e-40	131.0	2E9U2@1|root,33400@2|Bacteria,1VGEQ@1239|Firmicutes,258EK@186801|Clostridia,223BE@1506553|Lachnoclostridium	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
PKFBPKFJ_03900	411469.EUBHAL_02124	2.8e-45	147.0	COG0745@1|root,COG0745@2|Bacteria,1VCPH@1239|Firmicutes,24MRK@186801|Clostridia,25YZC@186806|Eubacteriaceae	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
PKFBPKFJ_03901	476272.RUMHYD_01402	6.79e-135	397.0	COG1277@1|root,COG1277@2|Bacteria,1VWKS@1239|Firmicutes,25M9V@186801|Clostridia,3Y21D@572511|Blautia	186801|Clostridia	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03902	476272.RUMHYD_01401	3.64e-150	429.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3XZE4@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
PKFBPKFJ_03903	476272.RUMHYD_01400	2.36e-64	208.0	2FFUY@1|root,347S0@2|Bacteria,1VYP7@1239|Firmicutes,253QZ@186801|Clostridia,3Y23M@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03904	476272.RUMHYD_03921	3.02e-74	228.0	COG1595@1|root,COG1595@2|Bacteria,1VH4V@1239|Firmicutes,25BGS@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_03905	515622.bpr_I2877	1.72e-168	477.0	COG4823@1|root,COG4823@2|Bacteria	2|Bacteria	V	Abi-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abi_2
PKFBPKFJ_03906	1121115.AXVN01000095_gene456	2.08e-10	60.8	2C2YH@1|root,31RJ6@2|Bacteria,1V7NS@1239|Firmicutes,24M7H@186801|Clostridia,3Y0EZ@572511|Blautia	186801|Clostridia	S	Bacterial mobilisation protein (MobC)	-	-	-	-	-	-	-	-	-	-	-	-	MobC
PKFBPKFJ_03907	411459.RUMOBE_00594	1.75e-91	267.0	COG0745@1|root,COG0745@2|Bacteria,1UVF6@1239|Firmicutes,25M0N@186801|Clostridia,3Y1TD@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
PKFBPKFJ_03908	411459.RUMOBE_00595	3.21e-285	780.0	COG1668@1|root,COG1668@2|Bacteria,1UY5S@1239|Firmicutes,24DP3@186801|Clostridia	186801|Clostridia	CP	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
PKFBPKFJ_03909	411459.RUMOBE_00596	1.52e-206	572.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3XZE4@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03910	411459.RUMOBE_00597	4.49e-183	509.0	29NVG@1|root,309TJ@2|Bacteria,1V4I1@1239|Firmicutes,24AMS@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03911	411459.RUMOBE_00598	5.3e-111	319.0	COG1595@1|root,COG1595@2|Bacteria,1VBJI@1239|Firmicutes,24NKR@186801|Clostridia,3Y1WC@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
PKFBPKFJ_03912	411459.RUMOBE_02193	7.11e-201	558.0	COG0642@1|root,COG2205@2|Bacteria,1UZ8S@1239|Firmicutes,25E8V@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
PKFBPKFJ_03913	411459.RUMOBE_02195	1.95e-171	479.0	COG1277@1|root,COG1277@2|Bacteria,1VIB7@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
PKFBPKFJ_03914	1121115.AXVN01000044_gene2043	2.97e-213	589.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,247M8@186801|Clostridia,3XZQA@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
PKFBPKFJ_03915	411459.RUMOBE_02197	4.65e-158	443.0	COG0745@1|root,COG0745@2|Bacteria,1TT2Z@1239|Firmicutes,248PN@186801|Clostridia,3Y028@572511|Blautia	186801|Clostridia	T	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
PKFBPKFJ_03916	1121115.AXVN01000044_gene2044	3.96e-68	206.0	COG1476@1|root,COG1476@2|Bacteria,1V6EB@1239|Firmicutes,24KVB@186801|Clostridia,3Y1QU@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
PKFBPKFJ_03917	1235802.C823_05456	6.98e-94	283.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1UQRR@1239|Firmicutes,24BSD@186801|Clostridia,25Y7A@186806|Eubacteriaceae	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
PKFBPKFJ_03918	1235802.C823_05456	2.51e-159	453.0	COG3335@1|root,COG3415@1|root,COG3335@2|Bacteria,COG3415@2|Bacteria,1UQRR@1239|Firmicutes,24BSD@186801|Clostridia,25Y7A@186806|Eubacteriaceae	186801|Clostridia	L	PFAM Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_32
PKFBPKFJ_03919	411470.RUMGNA_03479	3.12e-97	285.0	COG1846@1|root,COG1846@2|Bacteria,1UK34@1239|Firmicutes,24Y1H@186801|Clostridia,3XZJB@572511|Blautia	186801|Clostridia	K	COG NOG16925 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
PKFBPKFJ_03920	1121115.AXVN01000053_gene1847	1.07e-94	276.0	COG0394@1|root,COG0394@2|Bacteria,1V3JW@1239|Firmicutes,24HBX@186801|Clostridia,3Y0W0@572511|Blautia	186801|Clostridia	T	Low molecular weight phosphotyrosine protein phosphatase	arsC	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
PKFBPKFJ_03921	1121115.AXVN01000053_gene1846	9.55e-161	452.0	COG0798@1|root,COG0798@2|Bacteria,1TRMD@1239|Firmicutes,24958@186801|Clostridia	186801|Clostridia	P	PFAM Bile acid sodium symporter	arsB	-	-	ko:K03325	-	-	-	-	ko00000,ko02000	2.A.59	-	-	SBF
PKFBPKFJ_03922	457412.RSAG_00557	3.84e-169	472.0	COG0479@1|root,COG0479@2|Bacteria,1TP17@1239|Firmicutes,24AN0@186801|Clostridia,3WH5I@541000|Ruminococcaceae	186801|Clostridia	C	succinate dehydrogenase iron-sulfur	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_17,Fer4_8
PKFBPKFJ_03923	471875.RUMLAC_01055	0.0	1021.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3WSK9@541000|Ruminococcaceae	186801|Clostridia	C	COG COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
PKFBPKFJ_03924	457412.RSAG_00559	5.61e-115	330.0	28MNW@1|root,2ZAYB@2|Bacteria,1UZY0@1239|Firmicutes,24E0J@186801|Clostridia,3WIQY@541000|Ruminococcaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03925	1256908.HMPREF0373_00326	1.06e-111	322.0	28ITS@1|root,2Z8SN@2|Bacteria,1TRFF@1239|Firmicutes,24CE6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
PKFBPKFJ_03926	411461.DORFOR_00485	0.0	1313.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,27WBM@189330|Dorea	186801|Clostridia	P	Heavy-metal-associated domain	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
PKFBPKFJ_03927	1121115.AXVN01000053_gene1840	6.09e-81	239.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3Y1MZ@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain	ziaR	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
PKFBPKFJ_03928	411461.DORFOR_00483	3.12e-100	290.0	2B1F5@1|root,31TVV@2|Bacteria,1V9G6@1239|Firmicutes,24KHK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
## 3698 queries scanned
## Total time (seconds): 251.16244888305664
## Rate: 14.72 q/s