LOCUS       c00121_gnlPro..        17294 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PKFBPKFJ_121.
ACCESSION   c00121_gnlPro..
VERSION     c00121_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 00:56:19
            Original ID  :: gnl|Prokka|PKFBPKFJ_121
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 80338
            Orig. end    :: 97632
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17294
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[90338:92590]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12252
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..17294
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17294
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(212..1099)
                     /locus_tag="ctg121_84"
                     /transl_table=11
                     /translation="MELELKKLTKEFQGFKAVDDITLTMSNGVYGLLGVNGAGKTTLMR
                     MLCTLIKPTSGSILCDGKDIFALDGEYRRILGYLPQEFGFYPEFSVHDYLMYIASIKGM
                     RISIARKRVTELLRQVGLAKMQNRKMKKLSGGMKRRAGIAQAMLNNPKVLILDEPTAGL
                     DPNERIRFRNLISELSQDRLVLLSTHIVSDIEYIANQVLLMKDGKISHSGTQEEIIQSV
                     PVKVWSCVVANNEVEMWQKQFKVSNMKTLSDGIELRILSEKSPHYNAKEETMTLEDIFL
                     YYFGEKTGDAYDVL"
     CDS             complement(1169..1933)
                     /locus_tag="ctg121_85"
                     /transl_table=11
                     /translation="MMMTVDEKLHAYAKNQKDRNIDEKKLQQTIIKSKEAYWDGEIERN
                     MSWLEFLYQQASYIQKHWWFAQGAVLLILWMTMFLSDSSIYTRRCMGILAPSFVILILP
                     ELWKNRSNGAMEVEGATFFSIKNIYAARMLLFGMVDVCLLSVFLITSTFVLQIAFMDIL
                     IQFILPMNVTCCICFRLLCSKGDDYVSSTLFSCLIWIAVWTLVVLKDSIYEHISTSIWC
                     GMMILSVLYLCYSIWRVWKCSERYYESNGASV"
     CDS             complement(1930..2442)
                     /locus_tag="ctg121_86"
                     /transl_table=11
                     /translation="VDADFLLIHKMKNGDEEAIEVFVKKYYSTIRNYCRLHTYTDCDAE
                     DITQATFEHFFRSFRSYHHLGKTANYLYVIARNLCRDSYKKKRDIVMEALPDKGENPIA
                     VIENKIDIEESIKKLPEDLQEVVILHYFQDLKLKEVADIIGIGLPLVKYRIGKAKELLS
                     VYLGDKK"
     CDS             complement(2571..3488)
                     /locus_tag="ctg121_87"
                     /transl_table=11
                     /translation="MSVVLQIYAIIVTLSLIIVLSFYLLHRREVTRLSQKLQTLLHSFT
                     HAELTLDFPSSDITDLVNALNELLRVYHKQVYSLQKKDEAIKETITNLAHDLRTPVTAI
                     QGYTQMLLQSPELSEEDLDAAVVINERLNVLNQLLNQLFEFARIEADEMEFSYTTFDLN
                     AVLRSVAVSFFKSFEERKIIPALSIAEISFPFYGDEKAVTRIFENIISNALSHGKSDYH
                     FSSYDDNENYHFSFQNFTDSINESDIDKIFNRFYTTDLSRSRKTTGLGLTIAKNLTVKM
                     GGSISASLNNNVFEIVVCFPKQKG"
     CDS             complement(3508..4263)
                     /locus_tag="ctg121_88"
                     /transl_table=11
                     /translation="MLNLIRADFYKAIHGKVLKVCFLMMTGWIFLCAYAQKATIGMREY
                     LVGTEVSANYWDSFFNYYPVVFPLIIFCSYYFSNDFRQGTVKHYIEKGLSRWSYFLSKL
                     VIGWSVSFFFLVSAFLIGLLCNKIFFGISGLTFTSISNIVSYIFCEALYHMAVSTLAIS
                     LVFLIRNSSVSMAVNALLIFFGYLVLHGLESILGLGYNITIFWAISNINKTRIDMAVQW
                     LPTAIIIFFAYMIIFGGVIGTIFKKRDIT"
     CDS             complement(4256..5170)
                     /locus_tag="ctg121_89"
                     /transl_table=11
                     /translation="MEYILRTNTVSKKYTNYYAVDKVSISIKKGEIYGLIGENGAGKST
                     LMKMIAGLVEPSEGSIELFGNFVPQTERYRIGCVIESPALYAELTAKQNLEVFRKAYGL
                     SSKESVQQILKQVGLSQYENKIVKKFSLGMKQRLAIGVALLGNPDFLILDEPINGLDPT
                     GIQDMRNFLLKLNREEHITIMISSHILGELSKIATKYGIIKNGKLIEEITAKELNEKCQ
                     CCLKIKASDTAQAAILIEKNLHTKNYEILSDNNIRIFEYVDNPGIVNSLLVNHGISVDE
                     CTVTKESLEDYFNEKMRGGIVNA"
     CDS             complement(5250..5933)
                     /locus_tag="ctg121_90"
                     /transl_table=11
                     /translation="MNYTILIVDDDMAINDMLVKYLRKNGYITYSAYSGTEALLFLEKQ
                     KVNLIILDLMLPGLSGEQVLVEIKKTKNVPVIGLSAKEDSKSKIFLLKNGADDYVTKPF
                     DIEELLARIETILRRIYENQYTSNSLLCCGDLNLDTIGMEATLKNQKLPLTKNEFAILK
                     MLMEHPQQVFTKDMIYEQLWNETLEGTENAINVHISNLRKKIAAIDNSKSYIKTVWGIG
                     FKMDI"
     CDS             6507..6941
                     /locus_tag="ctg121_91"
                     /transl_table=11
                     /translation="MPALPYSITISDEERAYLKSLIKTRTIQAQVVDRARMLLWKSEAK
                     TDKAIADGLGVSVNTVRRCIDRYLNNGINLAIFDDERSGRPAEITDDAKSWIVSIACQK
                     PCDLGYAAELWTLAALHKHIQAHAEEAGYPRLKTVTKPWL"
     CDS             6957..7676
                     /locus_tag="ctg121_92"
                     /transl_table=11
                     /translation="MEIKPFKIKYYLERKDPDFENKMHDVLLVYKQVEMQFDDNGNIII
                     PDNGHLTHTISYDEKPGIQAVANKYPDYNPTEENGYIRRDYEYVRLGTLSLLAGIDLLT
                     GEAIPLVSQTHKSSDFIKFLKMLNAKYPEGDTIRLILDNHSAHTSKETRQFLAVLPEDR
                     FVFVFTPTHTSWLNMIESFFSKMTKQMLKGIRVNSKEELSERIYRYFDEINADPIVYHW
                     TYKYKMDEIDPDEVATI"
     CDS             complement(7673..8155)
                     /locus_tag="ctg121_93"
                     /transl_table=11
                     /translation="MKYEYMKESEQMLQYFQFPKFLLKLRISQTAKFLYMILYDRARIS
                     RKNSWIDKYGNVYLIFPIDELSVQIDKCKSSVKTALKELDDVGLLVRRSGGFSKPNHLY
                     VKIPSDEIGLQPVDNKAVEKIVATEPEKPPSSGRKNGCGGVGNVAPSTTNIKLLIV"
     CDS             complement(8202..8621)
                     /locus_tag="ctg121_94"
                     /transl_table=11
                     /translation="MLHPEQDPPVYYSIVILTILYYLRVADLMGITSPYPRENIIAGNY
                     ILADTQAFLSKCHRQQNKEILIRHSPGIGECFLFSNIQLTEKIKKISSGGCKNASQRFV
                     LMKGYLGGKNKKLSSRACIYALHLLNICKDIFEPA"
     CDS             complement(8827..9240)
                     /locus_tag="ctg121_95"
                     /transl_table=11
                     /translation="MNKKKVAFICVHNSCRSQIAEALGKHLASDVFESYSAGTETKLQI
                     NQDAVRIMKELYGIDMEAEGQYSKLIDEIPVPDIAISMGCNVGCPFIERPFDDNWGLED
                     PTGKSDEEFKKVIDEIRMQIFILKQRLDEFEEN"
     CDS             complement(9233..9976)
                     /locus_tag="ctg121_96"
                     /transl_table=11
                     /translation="MYEENQKLKTWITPDLATEYLAGAVLLGAAPCTAMVFVWSTLTKG
                     NPAYTVVQVASNDIIILFAFVPIVKFLLGVSNVSVPFQTLFMSVVLFVVIPLAAGIITR
                     LLVVRKKGTEYFEQTFLHKFDSATTVGLLLTLILIFMFQGEVVLDNPLHIILIAVPLII
                     QTFFIFFLAFGVCRIIRLPYDIAAPAGMIGASNFFELAVAVAVALFGTSSPAALATTVG
                     VLTEVPVMLTLVKIANKLKEKFKYE"
     CDS             complement(10001..10711)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 89.5; E-value: 4.5e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_97"
                     /sec_met_domain="Fer2_3 (E-value: 7.5e-28, bitscore: 89.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0044, bitscore: 10.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIHLVYKIRIRRQESQKSDSYWQEFEFDGSKNSSVANVLKELNSR
                     TPLKDNSGNIVTPISWECSCMVRKCGACAMLINECPRLACSTFLHTLKGSTITLEPLSK
                     FPLVRDLIVDRSILFENLKKLNLWLESEAYMNPWTHEPRYQSARCLMCGCCLEVCPNFS
                     ANGTFAGAVAAVNAFRILNEEQESTHLNEISAEYKKKYFEGCGKSLSCHDICPIGLPVE
                     ELLVRSNAAAVWGK"
     CDS             complement(10708..12252)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 269.9; E-value:
                     1.4e-82)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg121_98"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.3e-82, bitscore:
                     269.9, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.3e-16,
                     bitscore: 52.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTIIIIGAGLAGLSAALQAAENGCNVKLVSSLPSERAQSVMAE
                     GGINAALNTKDENDSPEEHFTDTIKAACGLADPNAVWGMTQAAPELVHWLLKLGVKFNM
                     SGYDDVDLRNFGGQKKKRTAFAQSDTGKQIMTAMIDAVRRKEASGMVERFSHHSFLTLR
                     LCGNICCGCVIRDEYSQETVELPGDAVIVATGGMHGLFGNTTGSLSNTGEVTAELFRLG
                     VPLANGEMIQYHPTTVKCGGKRMLISEAARGEGGRLFAMKDGKQWYFMEEKYPELGNLM
                     PRDITAREIWKVSHESEVFLDMTEISEEIISNKLSGLADDCMTYLHKDIRKEPVSVLPG
                     IHYFMGGILVDEQHRTPIQNLYAAGECCAQYHGANRLGGNSLLGALYGGRVAAKSACEQ
                     ADVVDLSCATQIDFPPASQISEIKQLNKVMQETMGVVRNENTLLNGIQTVQALTGNLPL
                     LGMAVLKSALARKESRGAHWREDYPKSNDDDYLKTTVARFDGKQIQISFVPVPERR"
     CDS             complement(12249..12788)
                     /locus_tag="ctg121_99"
                     /transl_table=11
                     /translation="MRKWNTILSVLMLLIFMIHGIMGSFMLNGVGSSAGKLLAWIGVGI
                     LVVHTVIGVILTVQSLQTAKQSGKMYLKQNAIFWARRASGLAILILLFFHIGLFGKVQN
                     GTYILFPFTTVKMVTQLLFVAAIFVHIFINIRPLLVSLGIISYKERRGDIYLILSVLLL
                     FIAGAVIFYYIGWQYL"
     CDS             complement(12799..13317)
                     /locus_tag="ctg121_100"
                     /transl_table=11
                     /translation="VKRKLILLVVTIVFLVGFGVILHSPPSMIDAVTGATPKSKKAAQA
                     SAQLEGSYVLGINMMSDGLDNENTRNKLKELALDDSETNETDLMKTDISFRLYVSETDY
                     PLVSYAKKLCDRLKQAGFSVDLKEYSNTMMLSRVVSGKYDVFLASDDFIDVTTLSQMDY
                     MIMDSEEMR"
     CDS             complement(13334..15457)
                     /locus_tag="ctg121_101"
                     /transl_table=11
                     /translation="MKRIFLLKGLDCPNCSAKIEKEVGELDGVQSSVVNLMKQTLTVNV
                     TQTAADTIASQIETIVYSHEPDVEVSEIVQESYIPEKKQEANESYNNEDKKLTVRLATG
                     AAIYAIGMALTVFAKVPLPIELAFLIVSYVILGGDVVWQAVRNISKGRVFDEHFLMSVS
                     TIGAFVIGEYPEAVAVMLFYQVGEFFQSLAVKRSRKSISDLMDIRPDSATVRRNGELIT
                     ISPENVSIGEIIIVKPGEKIPLDGVVLDGDSMLDTRALTGESVPRSVHKGDEALSGCMN
                     QTVVLMIKTTKAFGESTASKIIDLVENASSRKAPTENFITTFARYYTPVVVILAAFLAI
                     LPPIILGGGWTEWIRRGFVFLVVSCPCALVISIPLTFFGGIGAASKRGVLVKGSNYLEA
                     LNNVSVIVFDKTGTLTKGVFNVTDILPANGFSKEQVLEYAAEAESFSNHPIAKSILAAY
                     GKEMDQSVIFDYKEISGYGISVMAGEKKVFAGNTKLMDTECIEYTTCEKAGTKVYLAVD
                     GQYAGCILITDEVKPDSKKAISDLKHIGVEKTVMLTGDDEKIGKSVAEELQLDEYYAQL
                     LPDQKVEKVELLDSKKRPGSKLAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVV
                     LMTDEPSKLVDAIEVAKATKQIVMQNIVIALGIKSVFLILGALGIAGMWEAVFGDVGVT
                     IIAVLNAMRILKK"
     CDS             complement(15517..15876)
                     /locus_tag="ctg121_102"
                     /transl_table=11
                     /translation="MPKTSYICNCDVIHEDIVNDVKSKMQPKDDYIQLASLFKLFGDGT
                     RVQILHALEQSEMCVCDLAVLLGVTKSAISHQLKALRLANLVKFRKEAQIVYYSLADDH
                     VKEIIDKGFEHLWQK"
     CDS             complement(16008..16445)
                     /locus_tag="ctg121_103"
                     /transl_table=11
                     /translation="VATKVDKKNAIRQGITEAEIVYFQNLAGKTFLYVCGDEYFEVSFP
                     IDHFLHLTGVETRLSTKDFYKNAKKSILTNNQFYFDARHVYANAKRKLPCLKRLPELTN
                     EMVCVLKNMETMTITYKLSVTNLEFTGSVTRKPKRYTGKKD"
     CDS             complement(17135..17293)
                     /locus_tag="ctg121_104"
                     /transl_table=11
                     /translation="GARYFIRELLKPLPATERSLLEAKVRPVKRRTSCVYADLRELHLQ
                     MEILKVA"
ORIGIN
        1 aatttttcta agcacatcct ctgtcagttc tcctgaccat tcttttttca actcacgaac
       61 ctttaacata gccgatattc cactttccgc atcaccatta cgattcacat atttattatc
      121 cccgatgata aaagacaaga ctactgaaat tacaataaaa ataaatatca gcgtaacctt
      181 acttcctttt tttgaaaaaa ctttttttat ttcataatac gtcataagca tcacctgttt
      241 tctctccgaa ataatataag aatatgtcct ccaaagtcat cgtttcctct ttcgcattat
      301 agtgtggaga tttttcagac aaaatgcgta attctattcc atccgaaagt gttttcatat
      361 ttgagacttt aaactgtttt tgccacattt caacttcatt atttgcaact acacaactcc
      421 atacttttac tggtactgac tgaataatct cttcttgtgt tcctgaatgg ctaatctttc
      481 catctttcat caataacacc tggttggcaa tgtattcaat atccgacaca atatgtgttg
      541 ataatagcac gagacgatcc tgtgacaatt cactgatcag atttcgaaaa cgtatccttt
      601 cattcggatc cagacctgca gtaggctcat cgaggatcaa aacctttggg ttatttagca
      661 tagcttgggc aatccctgca cggcgtttca ttcctccaga caattttttc atttttctat
      721 tctgcatttt agccaaccca acctgccgca gaagttctgt tacacgcttt cgtgcaatac
      781 ttattcgcat tcctttaatt gacgcaatat acattaaata atcatgaacc gaaaactccg
      841 gataaaatcc aaattcttga ggtaaataac caagaattct cctatattcg ccatccaatg
      901 caaaaatatc ttttccatca cataatatgc ttcccgaagt aggtttaata agtgtgcaga
      961 gcattctcat cagcgttgtt tttccagcac cgttgacacc aagaagccca taaactccat
     1021 tactcatcgt cagcgtgata tcatcaactg ctttaaatcc ctgaaattct tttgttaatt
     1081 ttttcaattc taattccata atcaaattcc tcacatttct ctgattacga ccgttgtgtg
     1141 atttctcgta attgacacca taatagtctt atacacttgc cccattactc tcgtaatatc
     1201 tttcactgca tttccatact cgccaaatac tgtaacacaa atataaaaca gataatatca
     1261 tcattccaca ccatattgat gtagatatat gctcataaat actatctttg agaactacaa
     1321 gcgtccaaac agcgatccaa atcagacagg aaaataatgt ggaagataca taatcatctc
     1381 ctttactgca aagtaatcga aaacatatgc agcatgtcac attcattggc aaaataaatt
     1441 gtattaagat atccataaat gcaatctgta acacaaaagt gctggttatc aaaaacacac
     1501 tcaataggca aacatctacc atgccgaaga gtagcattcg tgcggcatat atattcttta
     1561 tggaaaaaaa tgttgcacct tctacttcca tagccccatt gcttctattt ttccagagtt
     1621 ccggaagtat caatattaca aaactcggtg ccaaaatccc catgcagcgc cttgtataaa
     1681 tactactgtc tgataagaac attgtcatcc aaaggattag taatactgcc ccttgagcaa
     1741 accaccagtg cttctgtata tacgaagctt gctgatataa aaattctaac catgacatat
     1801 ttctttcgat ttctccatcc caatatgctt ctttcgattt tataatggtc tgttgtaatt
     1861 ttttctcatc tatatttcta tccttctgat tttttgcata cgcatgcaat ttttcatcaa
     1921 ctgtcatcat catttcttat cccccagata aacactcaac aattcttttg cttttcctat
     1981 cctatatttt acaagaggaa gtcctatgcc aataatatct gctacttctt ttaatttcaa
     2041 atcctgaaaa taatgtagaa taactacttc ctgcaaatct tctggaagtt tttttattga
     2101 ttcttctata tctattttat tctcaattac agcaattgga ttttccccct tatctggtaa
     2161 cgcttccatc acaatatctc tttttttctt ataactatcc cgacataaat ttcgagcaat
     2221 cacatacaaa taattagcag tctttcccaa atgatgatac gatctaaatg atcgaaaaaa
     2281 gtgttcaaat gttgcttgag taatatcttc tgcatcacag tctgtgtatg tatgtaatcg
     2341 acaataattc cgtatagttg aatagtattt ttttacgaat acctctatag cttcttcatc
     2401 accatttttc attttgtgaa tcaaaagaaa atctgcatcc acttctttcc tcctttttct
     2461 actgaaagca ctttctatta tatataacga ataaattgta caaaaagata gtcaatacac
     2521 ctactttata agcgtttttt tttaaccacc aaagcaggct catcagtttt ttatcctttt
     2581 tgcttaggaa agcacactac aatttcaaaa acattattat ttagagaagc actgatagaa
     2641 ccgcccattt ttactgttaa attctttgct attgtgagac ccaaaccggt tgttttgcgg
     2701 gaacgggata aatctgttgt ataaaaacga ttaaatattt tgtctatatc agattcattt
     2761 atgctgtctg taaaattctg aaaagaaaaa tggtaatttt cattatcatc ataagatgaa
     2821 aaatgataat cacttttccc atgtgacaag gcattagaaa tgatattttc aaaaattctg
     2881 gttactgctt tttcatctcc ataaaatgga aaagaaatct ctgcaatact taatgctgga
     2941 attattttgc gttcctcaaa agatttaaaa aaggaaactg caacagagcg taaaacagca
     3001 tttaaatcaa atgtagtata agaaaattcc atttcatcag cttctattcg tgcaaattca
     3061 aacaactgat ttagtaactg atttaaaaca ttcaatcttt catttataac aactgctgca
     3121 tctaaatctt cctcggacaa ctccggcgat tgtagaagca tttgggtata tccttgaata
     3181 gcagtcacag gtgttctaag atcatgagct aaatttgtaa ttgtttcttt gattgcctca
     3241 tccttttttt gtaatgaata tacttgtttg tggtaaactc gaagcaattc atttaaagca
     3301 tttacaagat cggttatatc ggaagaagga aaatctaatg tcaattccgc atgggtaaat
     3361 gaatgtaaaa gtgtttgcaa tttctggctt aaccgggtta cctccctacg atgaagcaag
     3421 taaaatgata aaacaataat aagagatagt gtcacaatga tagcatatat ttgaagtacc
     3481 acactcataa cattatccct ccctgcatta tgtaatatct cttttcttga aaattgttcc
     3541 tataactcca ccaaatataa tcatataggc gaagaaaatg ataattgcgg ttggaagcca
     3601 ttgaactgcc atatctattc ttgttttatt gatattacta attgcccaaa aaattgtgat
     3661 gttatatcct aagcccaaaa tactttccaa tccatgaaga accaaataac caaaaaatat
     3721 aagcaaagca ttaactgcca tgctaactga actgtttctt atgagaaaaa caagtgaaat
     3781 tgcgagcgtt gatacagcca tatgatataa tgcctcacag aatatgtagg acactatatt
     3841 gctaatgctt gtaaaagtaa gaccgcttat tccaaaaaaa attttattac ataacaaacc
     3901 aattaaaaag gcagacacca aaaaaaagaa tgatacactc cagccaatta ccaattttga
     3961 taagaagtaa ctccatcgtg acagaccttt ttctatataa tgttttacag tcccttgacg
     4021 aaaatcattt gagaaatagt agctgcaaaa aataatcaaa gggaatacaa ccgggtaata
     4081 attaaaaaaa gaatcccagt aatttgcaga aacttctgta cctaccaaat attccctcat
     4141 gccaatcgtt gctttttgtg cataagcaca taagaatatc catcctgtca tcataagaaa
     4201 acatactttc aagacttttc catgtattgc tttataaaaa tcagctctaa ttaaattaag
     4261 cattgactat gcctcctctc attttttcat taaagtaatc ttccagtgac tcctttgtta
     4321 cagtacattc atcaacagaa attccatgat taaccagtaa ggagtttaca attccgggat
     4381 tgtctacata ttcaaaaatc cgaatattat tatcggaaag aatttcgtag tttttagtat
     4441 ggagattttt ctctattaaa atagcggcct gtgcagtatc tgatgcctta atttttaaac
     4501 aacattgaca tttttcattt aattcttttg cagtgatttc ttcaatcagc ttgccatttt
     4561 taataatgcc gtattttgtt gcaatttttg acaattcccc caagatatga ctggaaatca
     4621 taatggtaat atgttcttcc ctatttagtt ttaataagaa attcctcata tcttgtattc
     4681 cagtcggatc taagccattg ataggttcat caagaatcag aaaatcagga tttcccaaca
     4741 aggcaacgcc aatggctaaa cgctgtttca tacctaatga aaattttttg acaattttat
     4801 tttcatattg tgacagaccc acctgcttta aaatttgttg tacagattct ttacttgaca
     4861 gtccatatgc ttttctaaat acttccaaat tttgttttgc ggttaattct gcataaagtg
     4921 ccggagattc aatcacacaa ccaatacgat aacgctcggt ctggggaaca aaatttccaa
     4981 atagttcaat agagccttct gatggttcaa ccaaacctgc aatcattttc attaaagtag
     5041 acttaccagc accattttct ccaatcaagc catatatttc gcctttttta atagaaatgg
     5101 atactttatc aacagcataa taatttgtgt attttttaga tactgtgttc gttcttaata
     5161 tatattccat gatatatccc tccttgtggt tttagtgtaa gggataagtt taagtaaatt
     5221 attttctaaa tctaaggatt tcataaagat tatatgtcca tcttaaaccc aattccccaa
     5281 accgttttaa tatatgattt actattatct attgcagcaa tttttttgcg taagttgctg
     5341 atatgaacat tgatagcatt ttcagttccc tctaaagttt cattccataa ttgctcataa
     5401 atcatatctt tcgtaaatac ttgttgcgga tgttccataa gcattttcaa tatagcaaac
     5461 tcattttttg taaggggcaa tttttgattt tttagagtgg cctccattcc tattgtatct
     5521 aaatttaaat cgccacaaca taacaaggaa tttgatgtat attgattttc ataaatccgt
     5581 cgcaaaatcg tttcaatcct tgcaagtagt tcttctatat cgaagggttt cgttacataa
     5641 tcatcagcac cgtttttcaa taagaaaatt ttacttttag aatcttcttt tgcagataga
     5701 ccgattacag gtacattttt tgttttcttt atttctacta aaacttgttc gccagaaaga
     5761 ccgggaagca ttaaatccaa aataatcaga ttaacttttt gcttttcaag aaaaagaagg
     5821 gcttctgttc ctgaataagc agaatatgtt atataaccat ttttccgaag atatttaaca
     5881 agcatatcat tgatagccat atcgtcatca actattagaa ttgtgtaatt catataaaat
     5941 acctctcttt aacattgatc aatttgcaga atataatttt atggcatatt cgtatcaact
     6001 ttatcacaat cgtttgctat attcaatcat gtggctatct gacagcaaaa taaaatacta
     6061 cttaacatca aatttcatta cattctcata attcaacccg aaatgtacaa tgatataggg
     6121 tgatatgaga atgaaccaag atgaaatcag gtttgacttt catgggctcg ggctggcaat
     6181 caaacaagct agagaagaaa gaggctggac acaggcctat gtggcggagc tggtcggcaa
     6241 gacagaccgc acgattatga atattgaaaa taagggacaa catcccagct tcaatttatt
     6301 tttcaaactc gttaccatgt tcgatatttc cgtagaccag tttttctacc gggaagaaca
     6361 gcgggacgag cacagttgca gaaagcacat tgatgtactt ctcaactcca tgaatgaaaa
     6421 ggagctagta taacacaaat taagttgttg atagtttcag tatctggtat aatgaactta
     6481 ataaatacat tttatggagg tcaattatgc cagcattacc ttatagtata acaatatcag
     6541 atgaagaacg tgcctatctg aaatcactga tcaaaaccag aactattcaa gcgcaggttg
     6601 ttgaccgtgc gcgtatgctg ttatggaagt ctgaagccaa aacagacaaa gctattgcag
     6661 atggtcttgg tgttagtgtg aatactgtcc gccgctgtat tgaccgttat ctcaacaatg
     6721 gaattaacct tgctatattt gatgatgaac gttccggccg cccggctgaa attactgacg
     6781 atgcaaaatc atggattgtc agtatagcct gccaaaagcc ctgtgatctt ggctatgccg
     6841 cagaattgtg gacattagca gcactgcaca aacacataca ggcacatgct gaagaagccg
     6901 gctatccacg tttaaaaacg gttacaaaac catggcttta aaaatatctc aaaaagatgg
     6961 agattaagcc gttcaaaatc aagtattatc ttgaacgaaa agatcctgac tttgagaata
     7021 aaatgcatga tgtccttctg gtttataaac aggtggagat gcagtttgac gataacggaa
     7081 atatcatcat accggacaac gggcatttga cacatactat ttcgtatgat gaaaaacccg
     7141 gcattcaggc tgttgccaac aaataccccg actataatcc aacagaggaa aacggttata
     7201 tccgtcgaga ttatgagtat gtgcggcttg gaacgctgtc attgcttgca ggtattgatc
     7261 tcctgacagg tgaggcaatt ccattggtga gccagacaca caaaagttct gattttatta
     7321 agtttttaaa aatgctcaat gcaaaatatc cagaaggtga cacgatccga ttgatattgg
     7381 acaatcactc agctcataca tcaaaggaaa cacgtcagtt tcttgcagta ttgccagaag
     7441 atcgatttgt gtttgtattt acaccgacac acacctcgtg gctgaacatg attgaaagtt
     7501 tctttagcaa aatgactaag cagatgttaa aaggcattcg tgtcaattca aaggaggaac
     7561 tatcggaacg aatatatcgc tacttcgatg agatcaatgc tgacccgatt gtttatcatt
     7621 ggacatataa atataaaatg gatgaaattg atccggatga ggtagccact atttaaacta
     7681 tcaacaattt aatattcgtt gtactaggtg ccacatttcc gactcctcca cagccatttt
     7741 tacgaccaga tgaaggtggc ttttccggct ctgttgcaac tatcttttca accgccttat
     7801 tgtcaaccgg ctgtaaacct atctcatcag atggaatttt cacatataaa tgattgggtt
     7861 ttgaaaatcc accggatctg cgaaccaata gtcccacatc atctaattcc ttcaacgctg
     7921 tttttacaga agatttgcat ttatcgattt gaacagacaa ttcatctatt ggaaatatca
     7981 gataaacatt tccatacttg tctatccagc tattctttct cgatatccgt gcccggtcat
     8041 acaaaatcat ataaaggaat tttgcagttt gagaaattcg cagctttaat aaaaacttcg
     8101 gaaactggaa gtactgaagc atctgctctg actccttcat gtattcatat ttcattcttt
     8161 tctcgcctca tttctgtttc taattattgt aaaaatcatt tttatgccgg ctcaaaaatg
     8221 tccttacata tattcaaaag atgaagggca taaatacagg ctcttgagga aagtttttta
     8281 tttttcccgc ccaaataccc tttcattaat acgaaacgct gagaggcatt tttacagccc
     8341 cctgatgaaa tttttttaat tttttcggtt aattgaatat ttgaaaacaa aaaacactca
     8401 cctattccag gtgaatgcct tatcaaaatt tccttatttt gttgtctgtg acacttactc
     8461 agaaacgctt gcgtgtctgc taaaatgtaa ttgccagcaa ttatattttc acgtgggtat
     8521 ggggacgtaa tccccatcaa gtctgctact cgtaagtaat acaaaattgt caaaatgaca
     8581 atactgtaat acacgggtgg atcttgctct ggatgtaaca tatgaattca tgcaataata
     8641 ggcccaaatg ggcactttcg ccatttgagc ctatatattg tatgtctttt ggatgcccct
     8701 ttgaaatagc ctctgctggc ataaaagaag gcagacagtc ttgttataaa accacctgcc
     8761 ttgttgatta ttcttatatg ttttttgtat ctcatccgtt cgacaaactg caatttctca
     8821 acttctttag ttttcttcaa attcatccaa tcgttgtttc aatataaaaa tttgcatcct
     8881 tatctcatca ataaccttct taaactcttc gtcactcttt ccggttggat cttcaagtcc
     8941 ccaattatca tcaaacggtc tttcgataaa cggacatccc acattacaac ccattgaaat
     9001 tgcaatatcc ggtactggta tctcatcaat cagcttacta tattgtcctt ctgcttccat
     9061 atcaattcca tacaattctt tcataatccg gactgcatcc tgattaatct gtagtttcgt
     9121 ttctgtccct gccgaataac tttcaaatac atccgaagcc agatgttttc ccaaagcttc
     9181 tgcaatctgg cttctgcatg aattatgaac gcatataaaa gcaacttttt tcttattcat
     9241 acttgaactt ctcctttaat ttgtttgcaa tcttcacaag agtaagcatt accgggactt
     9301 ctgttaatac acctactgta gttgccagtg ccgctggact tgatgtacca aataaagcta
     9361 cagcgactgc aacagctagc tcaaagaaat tcgatgcacc aatcattcca gccggggctg
     9421 caatatcata cggaagtctg ataattctgc atactccaaa tgccagaaag aatataaaga
     9481 atgtctgaat gatcagcgga actgcaatca atataatgtg cagtggattg tccagcacca
     9541 cctcgccctg aaacataaaa atcagtatca gcgtgagcaa aagtcccact gttgttgcgg
     9601 aatcaaattt atgcagaaaa gtctgctcaa agtattccgt acctttcttt ctgactacca
     9661 gcagccttgt tatgattccg gctgcaagtg gtattactac aaatagaacc acactcataa
     9721 ataacgtctg aaacggaaca ctaacattag aaacaccaag cagaaatttc acaatcggta
     9781 caaatgcaaa taatataata atgtcatttg atgccacctg aactactgta taagctggat
     9841 ttccctttgt cagcgtactc cagacaaata ccatagcggt acatggggct gctccgagaa
     9901 gcacggctcc tgcgagatac tccgtcgcaa gatccggtgt gatccatgtc ttaagttttt
     9961 gattctcttc atacattcat tatagctttt atcatccatt ttatttgccc caaacagccg
    10021 ctgcattcga ccttacaagc agttcttcca caggcagacc aatcggacaa atatcatgac
    10081 aagataacga cttcccgcat ccctcaaaat atttcttctt atattcagca gaaatctcat
    10141 tcaaatgagt gctttcctgt tcttcattca gaatccgaaa tgcgttgact gcagcaacag
    10201 cgcctgcgaa agtcccattt gcagagaagt tgggacacac ttcaaggcag cagccacaca
    10261 tcagacagcg tgccgactgg tatctcggtt catgtgtcca cggattcata taagcttcac
    10321 tttcaagcca aaggttcagt tttttcaaat tttcaaacag aattgaccgg tcaacgatca
    10381 aatctcttac aagcggaaat ttgcttaaag gttccaaggt gattgtagaa ccttttaacg
    10441 tatgtagaaa tgtagagcat gccagcctcg gacattcgtt aatcagcatg gcgcaagccc
    10501 cacattttcg caccatacag ctacattccc agctgatggg agtaactata ttccctgaat
    10561 tatctttcaa aggggttcta ctgttcaatt cctttagaac attggcaaca gagctgtttt
    10621 tgcttccgtc aaactcaaat tcctgccaat aactgtctga tttctgactc tcctgccgcc
    10681 tgattcttat tttatatacc aagtgaatca ccgcctttct ggaacaggta caaaggaaat
    10741 ctgtatctgc tttccatcaa atctggctac cgttgtttta aggtaatcat cgtcattgct
    10801 cttcggataa tcctcccgcc agtgtgcacc acggctttct tttcttgcaa gagcactctt
    10861 tagaactgcc atgccaagca atggaagatt tcctgtcagc gcttgtaccg tttgaatccc
    10921 atttaacaac gtattctcat ttctgacaac gcccatagtc tcctgcatca ctttgtttaa
    10981 ttgctttatt tctgaaattt gagacgctgg tggaaaatct atctgtgtcg cacaagatag
    11041 atctactaca tctgcctgtt cgcatgctga ttttgccgca acacgtcctc cgtataacgc
    11101 tcctaacaga gaatttccac caagacggtt ggcaccatga tattgggcac agcattctcc
    11161 ggcagcgtaa agattctgaa tcggcgttct gtgctgctca tccaccagaa tacctcccat
    11221 aaaatagtga attcccggta aaacagacac cggttccttt cgtatatctt tatgcaaata
    11281 ggtcatacaa tcgtctgcca gaccagatag cttatttgaa ataatctcct ccgatatttc
    11341 cgtcatgtca agaaatacct ctgattcatg gctgaccttc catatctctc tggcggtaat
    11401 atctcgtggc atcagatttc caagctccgg gtatttttcc tccatgaaat accattgttt
    11461 tccatctttc atggcaaaca acctgccacc ttcccctctg gccgcctcgc tgatgagcat
    11521 gcgttttcca ccacatttca cagttgtcgg atgatactgg atcatctcgc catttgccag
    11581 aggaacacca agccggaaca attctgcggt gacttctcct gtattgctca gcgaacccgt
    11641 tgtatttcca aacaatccgt gcataccacc ggtggcaaca ataaccgcat cccccggtaa
    11701 ttccacagtc tcctgactgt attcatccct gattacgcag ccacaacaaa tattgccaca
    11761 cagacgaagt gttaggaaag aatgatggct gaaccgttct accataccag atgcttcttt
    11821 cctgcgaaca gcgtctatca tagctgtcat gatctgcttc ccggtatcgc tctgtgcaaa
    11881 agcagtccgt ttctttttct gcccgccaaa atttcgcaga tccacatcat catagccact
    11941 catgttaaat ttaactccaa gttttagcag ccagtgcacc agctccggtg ctgcctgtgt
    12001 cattccccaa actgcatttg gatctgccag accacatgct gcctttattg tatctgtaaa
    12061 atgttcttcg ggactgtcgt tttcatcttt tgtattcaaa gctgcgttga taccgccctc
    12121 cgccataaca gactgtgccc gctctgacgg aagggaggaa accagtttta cattgcatcc
    12181 attttccgct gcctgcaaag ccgctgaaag tcctgccagt ccagcaccta taataataat
    12241 tgtcttactc atagatattg ccacccaata taatagaaaa taactgcgcc cgctataaac
    12301 agaaggagca ccgaaagaat caaataaata tcaccccttc gttctttata actgatgatt
    12361 cccagcgata cgagcaatgg gcggatattg ataaaaatat gaacaaagat tgccgccacg
    12421 aacaaaagct gagttaccat ctttaccgtt gtaaaaggga acaaaatata tgtcccattc
    12481 tgcacctttc caaacaagcc aatatggaag aacagcagga tcagtattgc cagcccactg
    12541 gctcgtctcg cccagaatat ggcgttctgt ttcagataca tttttccgga ttgcttcgct
    12601 gtctgtaaac tctgaactgt caggatgaca ccaatcaccg tatgcacaac aagaatacca
    12661 acaccaatcc atgcaagaag tttccctgca ctacttccaa ctccgttcag cataaagctt
    12721 cccatgattc catgaatcat aaaaatgaga agcattaaaa cagacaaaat cgtattccat
    12781 tttctcataa attcccgctc acctcatttc ttcgctgtcc atgatcatat agtccatctg
    12841 tgataacgtt gtaacgtcaa taaaatcatc cgatgccagg aatacatcat actttccact
    12901 taccactctt gatagcatca ttgtgttact gtactctttc agatctacgg aaaaaccggc
    12961 ctgtttcaat ctgtcacaga gtttcttagc ataactgaca agcggataat ccgtctcaga
    13021 tacatataac cgaaaactaa tgtccgtttt catgagatct gtttcatttg tttccgaatc
    13081 gtccagtgcc aattctttta atttattccg ggtgttctcg ttgtcgagac catctgacat
    13141 catattaata ccgagaacat aagagccttc caactgtgcg gaggcttgag ccgccttttt
    13201 tgacttcggt gttgctcctg tgactgcatc aatcatagaa ggcggtgaat gtaatatgac
    13261 accaaaacct acaagaaaaa caatcgtaac aactaacaga atcagttttc gtttcacatt
    13321 cccacctcat ttcctatttt ttcaaaattc tcattgcgtt caaaacagca attatggtaa
    13381 cgcctacatc accaaataca gcttcccaca ttcccgcaat accaagagcg ccaagaatca
    13441 ggaacacact cttaatccca agagcaatca ctatattctg catgacaatc tgttttgtcg
    13501 cttttgctac ttcaatcgcg tccaccagct tagacggttc atctgtcatc agaactacat
    13561 ctgctgcttc aatggccgca tccgaaccaa gcccacccat tgcaatacca acatctgcac
    13621 gggcaaggac aggagcgtca ttgataccat caccaacaaa agccaatttg cttcccggtc
    13681 tctttttact atctaaaagc tcaacctttt ccactttttg gtcaggaagc agctgtgcat
    13741 aatattcatc caactgcaat tcttctgcaa cagacttccc aattttttca tcatcaccgg
    13801 taagcatgac tgttttttcc acgccgatat gtttcaggtc agaaattgct tttttactgt
    13861 ccggcttcac ttcatctgtt atcaaaatac atcctgcata ttgaccatct acagccaaat
    13921 aaacttttgt acctgctttt tcacaggttg tgtactctat acattctgta tccataagtt
    13981 tcgtattgcc agcaaaaact ttcttttccc ctgccattac actgattcca tatcctgaaa
    14041 tttccttata atcaaaaatc actgactgat ccatttcttt tccataagca gcaagaatgg
    14101 attttgcaat aggatggtta gaaaaactct ctgcctctgc cgcatactcc agaacctgtt
    14161 cttttgaaaa tccatttgca ggcaaaatat ccgtcacatt gaaaacacct tttgtaagtg
    14221 ttccggtttt atcgaacaca ataacgctga cattattaag tgcctctaaa taattgcttc
    14281 cttttacaag aacacctcgt ttagatgctg caccaatgcc gccgaagaaa gtcagcggga
    14341 ttgaaataac caatgcacat ggacaagata ccacaaggaa aacaaatcct ctgcgaatcc
    14401 actctgtcca gcctccgcca agaatgatcg gtggcagaat cgccagaaaa gctgctaaga
    14461 ttacaaccac aggtgtataa taacgtgcaa atgtagtaat aaaattttct gttggtgctt
    14521 ttcggcttga cgcattttcc acaagatcaa taatctttga agccgtagat tcaccaaatg
    14581 cttttgttgt cttaatcatt aagacaaccg tctgattcat acaaccggaa agtgcttcgt
    14641 ctcctttatg aacacttctc ggaactgatt ctcctgttaa ggcccttgta tccagcatag
    14701 aatctccatc caataccaca ccgtctaatg gaattttttc accaggcttt acaataataa
    14761 tctcaccaat ggagacattt tctggagata tggtaatcaa ttccccattt cttcttactg
    14821 tagcagaatc tggacgtata tccattaagt ctgatataga ttttctggaa cgcttaacag
    14881 ccaatgactg aaaaaattca cctacctgat agaatagcat aacagcaact gcttctggat
    14941 attcaccaat aacaaaagcc ccaatcgtag aaacactcat caaaaaatgt tcatcaaata
    15001 cacgcccctt tgaaatgttc ctcacagcct gccatacaac atctccacca agaataacat
    15061 aagaaacaat gagaaaagct aactcgatag gcagtggcac tttcgcaaaa acagtcaatg
    15121 ccataccaat ggcatagatt gctgcaccag tcgctaaacg aactgtcaac ttcttatcct
    15181 cattgttata ggattcattg gcctcctgct ttttttccgg tatataagat tcctgtacaa
    15241 tttcagaaac ttccacatct ggctcatgac tataaacaat cgtttcaatc tgactggcta
    15301 tcgtatctgc ggctgtctga gtaacattga ctgtaagcgt ctgcttcatc agatttacca
    15361 ctgaggattg cactccatcc aactctccga cttctttttc aatttttgcg gaacaattcg
    15421 gacagtccaa cccttttaat agaaatatgc gtttcatgat aatctcctta taatttgttt
    15481 aattgttcaa ttactcaact ataatgttaa aaaatattat ttctgccaaa gatgctcaaa
    15541 tcccttgtca ataatctctt tcacatgatc atctgccagt gagtagtaaa ctatctgtgc
    15601 ttctttacgg aattttacca gattcgcaag gcgtaatgcc tttaactgat gcgaaattgc
    15661 agattttgtt acccccagta gcactgcaag atcacataca cacatctcac tctgttctag
    15721 agcgtgtaag atttgtactc tagttccatc tccaaatagc ttaaacaaag aagccaactg
    15781 gatataatca tcttttggct gcatcttgga tttcacatca ttcacaatat cctcatgaat
    15841 tacatcgcaa ttacaaatat aagacgtttt tggcatatat tcacctccaa ataataatag
    15901 ttgaacaatt actcaactat tattatactt atttttaaat tcatgtcaat aagctgatgt
    15961 tagttcccca taaattttac aattaaaacc agctctttat tcttttctta atcttttttc
    16021 ccagtatacc gttttggctt tcttgtcaca cttcctgtaa attccaaatt tgtaacgctg
    16081 agtttatatg taattgtcat ggtttccata ttttttagaa cacataccat ttcattcgtt
    16141 aattccggca agcgttttaa acacggaagt ttccttttgg catttgcata tacatgtctt
    16201 gcgtcaaaat agaactgatt atttgtaaga atagattttt ttgcattctt ataaaaatcc
    16261 ttggtcgaaa gtcttgtctc cactcctgtt aaatgtagaa agtgatctat tggaaaagaa
    16321 acttcaaaat attcatctcc acaaacatac agaaatgttt tacctgccaa attttggaaa
    16381 tatacgattt ccgcctctgt aataccttgt cgtattgcgt ttttcttatc tacctttgtt
    16441 gccacttata cctcacatgc aaaaaagagt gtggcattaa accacacttt tctgagaatt
    16501 acttttgtaa aagagttttc tgctggttgt cagcctcgat acccagttaa gatacccata
    16561 acgacgtgaa aatcattaag tcccccacgt ggactacagc tttatccaag ctaccaggct
    16621 cgatgcccag ttaagacatc taatgagatg gaagtttacc ctgctccatc tgcagcccaa
    16681 cttttaacga tgctcttaca tcgagaacat ttctgttctt gattttatta tactcaatca
    16741 taaaaaaaat caacacagat tagcaaattt tattatatta ttccgatccg gtcttccaaa
    16801 ggtataaata aggtgtaaat tattggttaa ttcccaagaa atccaataaa atcaaggctt
    16861 tcacggcatc cattaaacat tgccgtggca gacaaataac actcttatca ttgcttaaaa
    16921 ctccttgaaa tgctgtattt acgctgttta caggcatttt ccgataatcg tgaacctcac
    16981 atggctaaag tcacgtgctt ccagacgctt taggcgtcag actgaatatc ggcggatacg
    17041 cctgtaactt aggtctgcac agttatgtgc tttttccatg ccggatacgg caggttccca
    17101 cattacaggt aatccgctgt atatctgcct gtgtttatgc tacttttaag atctccattt
    17161 gcagatgaag ttctcttaag tcagcataaa cacatgaggt tctacgcttt acaggacgga
    17221 cttttgcctc cagtaaagac ctttccgttg ccggaagggg ttttaaaagt tcccttataa
    17281 aatatctcgc ccct
//
