LOCUS       gnlProkkaFPGNHDDM_49   32027 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FPGNHDDM_49.
ACCESSION   gnlProkkaFPGNHDDM_49
VERSION     gnlProkkaFPGNHDDM_49
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:43:36
            Original ID  :: gnl|Prokka|FPGNHDDM_49
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 32027
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     cand_cluster    1..32027
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-ii"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..32027
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     protocluster    1..16097
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2959:6097]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2960..6097
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..16097
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     CDS             59..820
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 205.7; E-value:
                     1.3e-62)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_1"
                     /transl_table=11
                     /translation="MLEILIAEKIYKTYNNSFIDRVHSEKRNEVLKGVDLTVGEGECIG
                     IMGKSGCGKTTLLKILGTIEKASKGKILFQGEDIERLSDELLSELRRKTLGFVFQDYKL
                     LNSLTVKENIIIPMVLEKKNKTYIDKKISEEVELLGISSILNKYPYEISGGEKQRVAIA
                     RALANDPKLILADEPTGNLDSASALTIMDSLVKVNKKAKKALIIVTHDPLVASYCEKIL
                     FLKDGSIIDQINSPIDQKQKYKKIIDTMINL"
     CDS             1157..1486
                     /locus_tag="ctg49_2"
                     /transl_table=11
                     /translation="MQNVFPEYKSEIILGNGKFQIDPMAYNVIYEGKQIGLTPREFEVL
                     YFLAQKPNWVIPKKNIYHSVWGIHYHDDQIPYRTVEYVIWKIRKKMGHDIIETLVNVGY
                     RLKKL"
     CDS             1546..2043
                     /locus_tag="ctg49_3"
                     /transl_table=11
                     /translation="MNGNKKSAKQYHQSVITALEKKVNDMKDSAYSGLYSEIAFIIGIA
                     VIMIDTFFPPEETKVNCVWKIILIAVSIVCMLYFAKKVKTVNEVEEEKKFWPNFFIQWA
                     TSLGYINMPVAVIAILVTFDKGKAWTLFMMGVAVILTGLTLIEALVKTSKILKKENVGK
                     RK"
     CDS             2656..2859
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_4"
                     /transl_table=11
                     /translation="MSEMRNPITREENFSNPAGNVMMELQEADLNKFVAGAGETRNSGG
                     VLCTSTAECYFGTLLKPCCPKK"
     CDS_motif       2656..2700
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MSEMRNPITREENFS"
                     /locus_tag="ctg49_4_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       2701..2859
                     /prepeptide="core"
                     /locus_tag="ctg49_4_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="5358.1"
                     /monoisotopic_mass="5354.6"
                     /core_sequence="NPAGNVMMELQEADLNKFVAGAGETRNSGGVLCTSTAECYFGT
                     LLKPCCPKK"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSEMRNPITREENFS"
                     /leader_location="[2655:2700](+)"
                     /alternative_weights="5376.2"
                     /alternative_weights="5394.2"
     CDS             2960..6097
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     869.5; E-value: 5.4e-263)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_5"
                     /sec_met_domain="DUF4135 (E-value: 5.4e-103, bitscore:
                     339.4, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6.4e-54, bitscore:
                     177.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTERASYFTERSYTTSEAENKKDIFEYWKKILGEDTLRVAEKCY
                     GIDLVKVLNSENYVCENNHVMSEMEKVKIELFEKPINYNYSGFKGEKLAFDNFFIPLIN
                     YGIDILKNGTSLFLTDSIIDTYANTLLERLGKISLGILMFEMYLCKKTGKLNGRNSEEE
                     YDYYNNNFLSKKSYKQELFNIYPCLLRSVTETVENLSSYYVLLLERLNKDKNEIANKFC
                     GGLEFKNVVEISSNISDSHKKGNGVSILKLDNGTKIVYKPRSLKIEKVYFDFLGKINAG
                     CKYEMYEPKILDCQEYGWEEFVYYKSCKTEDEIRRYFYRFGILIFGSYILNTNDLHEEN
                     VIAAGEYPIIIDAETILDNRRRGRTNSAKEEINYILHESVLYSGLLPHYRFSNLGQGVD
                     MSAIKGSEGKEYPIVIPKIADLCTSNMRFVYEHPTTGVNQNLVKLDGENVSAFHYLKEI
                     NAGFEDAYKYVLENKEKFLEYADMFGNLNIRHLVQDTQRYSMLLHTSFHPDFMQDGRDR
                     QMFLCSLFKQYEATQGDKGVVKCEIKDMLNMDIPYFYLNTSGKSLFGSEGEKIEDYFEY
                     TSLEHLKKKIVLLDEDDLKRQLMFMNIILTEINEFQVEDKKIELQQMKMIPHREKNKAH
                     LLKAVQKLADSLIKTAVFNKDRTEVNWIGVTLIGNEDDCSWDIRPLGTYLYEGMSGLAI
                     FFNALYTVDPQKEYLIICNAIEKELFTYTDEMCERNEGIENESSGAFGGEASIMYTYEV
                     LYKITNKEKYLDYAKKHYKILKKAITRDNSFDLVYGNAGAVITLINMYQLTGNKEYIAS
                     AEIAGDIIVNAQEKEGSIKGGWNGDGRTSPLAGFSHGASGIVLALAKLWQVTQKEEYLL
                     SLLDGIKFENSLFVKEKGNWKDERVYAGEKASDGGSFTVAWCHGAAGILLSRSKVNVIL
                     NGRYSDLIENDIKVAVNTILKEGILGNNCLCHGNLGNTEILFEYLKDHSDKKIEKYYVD
                     IRDIIAENVCNGVFDCDNAYLYGYKLQGFMTGLCGMGYSLLRDIKKDLPCVIALEV"
     CDS             6168..8270
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 266; E-value: 1.1e-80)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_6"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.5e-27, bitscore:
                     89.8, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHKKSVPLIRQMGTTDCGIAALTMIFQYYKYKIDISELKATTSIG
                     RNGMSLAKMKEITEEHNFSFKAYGNYETEENLIKCLPIIMCSKENHYVVVAEKKYGKYI
                     LLDPLKGKEKVDYSYIKKNFLDVLVCVRPTEKNYKREKRESFLIPINKSKLFLASILTL
                     VTQGIILIPPLIIKKIVNEITYDTLGFNFVKYALLILSVALSYLLANLAKKRVILILQN
                     NIYKDTIFLMLNKIFDIDLSYFESHSSGDIENRFNSVSDIYEFISTALISTVIDVVTAV
                     FCGIMMITQSIPLFAVIIVMTVIQITIVMILNQKARIKVKNYIADQSALQARMVETLTN
                     IQQIRCMRIENMLSDSLKQDYKHLIKRLRERVQISDIMESVVGAFSIASSLILYVIGGY
                     LVCDNRLELGTLIAFVTLAGYFTGPFQTLSLVVPQINVLKETMIRLKELMNYKSNRKNG
                     TQHINSFESMEMQQVTFSYYGSTKPDVENVSMMLKKGEKIAFVGSSGSGKTTITKLLLN
                     VFSHYQGQILVNGEDIKQICKEDIDRIFAIVTQVPMAMNGTIRENVDITNTLTDEEIYH
                     YLDLVELKDDIEKFPLGLNTFVGENGQNISGGQKQRIAIARALALKPEVIIFDEATSNL
                     DPLTERRICNNLKQLHITQIVVTHRLNAIQDADTIYVVEKGKIIESGTHVELLQLKGAY
                     YDSVNN"
     CDS             complement(8310..9704)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 107; E-value: 2.2e-32)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg49_7"
                     /transl_table=11
                     /translation="MKLAKRFFKKYLLSTLIILILFFVLNIILICGTLLMAWNNSTDPD
                     IPVQTISKNITLNVDGTISSTDYIENTLKNKSAWAMILNEQGNVIWEKFLPEELPRTYS
                     NLQIAKFSRWYLQEYPVFIQEHSAGLLVIGCEPNSITKYNFSIDINYIHSLIVGIFLMI
                     CFNILLIFILFWRNTHKIEKSIVPIIDGIDSIAQGKPITLSETGELSSINAELNKAGKH
                     LLQKEQARAEWINGVSHDVRTPLSIILGYASEIEKNEDASQPVQLQASIIRKQSEKLRS
                     LIADLNLTSRLEYSMQPLIKTSFSPVEIARQVIIGFMNGPIDNKYSFDFHSSSDMIPVL
                     IKGDTELFSRMLSNLIQNCINHNPHGCEITVEILKENDTCIISVIDNGDGMTSTQIEKM
                     NSGIFPNNMYNSNGESVHGFGLKLVYQILTAHNGNIKYENILPHGLKVILEIPIEHIDP
                     YEEKIS"
     CDS             complement(9704..10396)
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 195; E-value: 2.1e-59)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg49_8"
                     /transl_table=11
                     /translation="MYDKFILIVDDEQELLTLIKTIFERAGYTKIMTATSGEMALQIIR
                     ETLPDMVILDVMLPGMDGFEVLQEIRALSKLPVLMLTAKDAAEDRFSGFELGADDYLIK
                     PFLPKELLLRVQAILKRSYPTEKRIIELENSFIDIDKAEIHRENKIIPLTAKEYNILLK
                     LVDNANHIVTIGTLCQTACGEMWQGYETTLMTHIRHLREKIEKNPSSPVSLLTVKGLGY
                     KLLVKGVK"
     CDS             10442..10540
                     /gene="allorf_010442_010540"
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="allorf_010442_010540"
                     /protein_id="allorf_010442_010540"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MWKKKYRERGKSQGYLKVTSRKSQCSWYIITV"
     CDS_motif       10442..10486
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence: MWKKKYRERGKSQGY"
                     /locus_tag="allorf_010442_010540_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       10487..10540
                     /prepeptide="core"
                     /locus_tag="allorf_010442_010540_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="1922.3"
                     /monoisotopic_mass="1921.1"
                     /core_sequence="LKVTSRKSQCSWYIITV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MWKKKYRERGKSQGY"
                     /leader_location="[10441:10486](+)"
                     /alternative_weights="1940.3"
                     /alternative_weights="1958.3"
                     /alternative_weights="1976.3"
                     /alternative_weights="1994.4"
     CDS             complement(10717..10932)
                     /locus_tag="ctg49_9"
                     /transl_table=11
                     /translation="MDKNNCDNNSYFYERNYYKDVPIKDTQILEYWNNILGKDVIELID
                     KAHFVCIRLPDPSIRPGNALEHVSYS"
     CDS             11196..11612
                     /locus_tag="ctg49_10"
                     /transl_table=11
                     /translation="MSKKRAPGRSLDEWMDLVTECRQSGLTDAAWCNEHGISPSCFYNA
                     VTRLRKKVCQIPDPVGKASTLDLTSHKQDVVQIAIEPESSPAGLIPDNGNRPMHLDNSH
                     TIEIEADGLLIRMSNEIKPLLLKMLMDTLKESLC"
     protocluster    11292..32027
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[21291:22027]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      21292..22027
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="2"
     cand_cluster    11292..32027
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             11606..11944
                     /locus_tag="ctg49_11"
                     /transl_table=11
                     /translation="MLADISSVDAIYIVCGRTDMRKSIDGLCAIIQEQFSMEIDHALFL
                     FCGRKCDRIKAILKEPDGIVMIYKRLTAQGSYRWPRNKSEVRNLTWREFDWLMSGIDIE
                     QPKAIKAT"
     CDS             12078..13754
                     /locus_tag="ctg49_12"
                     /transl_table=11
                     /translation="MADSSKDIQLRELKDMINDLKKMIKTLQATVDAANKREEALTQER
                     DNLKEEIDLLRKKLFGTSSEKRTLDIPGQLNFFNEAELEQDPKAAEAEDLEAILPEKTA
                     KKRKARATDAERFKGVPVEKKYLELSEEEKLCPVCGIPLKEIGEEFVRRELVFVPAKLK
                     VYEYYSKSYECPQCRLQDIPVIKKGKDGRAHMLYGMASAGTVAWVMYQKFCNGLPYYRQ
                     EKDWKQYGVEITRATMANWVLRNSEAFFLPMYEYFHRKLLKRGFVMADETPLQVLHEPE
                     RRAQTKSYMWLFRSGEDGGPPIILYKYSETRAGDNAVDFLHGFKGYLMCDGYSGYNKVP
                     DAKRTACWAHIRRYLTDAIPKGKALDYTQPSVQGMLYINQLFHLEDVIRSKYSSFDAIK
                     KARLEKEKPVVEGFLSWLDQQNPIRGSRMDKAVTYIQNRRSYLSTYLEDGRCSFSNNLS
                     ENAIRPFTVGRKNWLFCDTPNGAQASAIVYTMVEMAKANGVNVYHYLTYLLEKLPDDRM
                     SDDELELLAPWNETVKAEIERRANESNQSYVNCQGAPATEK"
     CDS             complement(13783..13980)
                     /gene_functions="biosynthetic-additional (lanthipeptides)
                     predicted lanthipeptide"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg49_13"
                     /transl_table=11
                     /translation="MKKNYRNPMTRPENFMNPAGNVMKEIKEADLNNFSAGAGEPRVSD
                     GSQFCTSTKECNWGTIMVSA"
     CDS_motif       complement(13840..13980)
                     /prepeptide="leader"
                     /note="peptide class: {self.peptide_class}"
                     /note="predicted sequence:
                     MKKNYRNPMTRPENFMNPAGNVMKEIKEADLNNFSAGAGEPRVSDGS"
                     /locus_tag="ctg49_13_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(13783..13839)
                     /prepeptide="core"
                     /locus_tag="ctg49_13_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.40"
                     /molecular_weight="1916.2"
                     /monoisotopic_mass="1914.9"
                     /core_sequence="QFCTSTKECNWGTIMVSA"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MKKNYRNPMTRPENFMNPAGNVMKEIKEADLNNFSAGAGEP
                     RVSDGS"
                     /leader_location="[13839:13980](-)"
                     /alternative_weights="1934.2"
                     /alternative_weights="1952.2"
                     /alternative_weights="1970.2"
     CDS             14336..15190
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 158.4; E-value:
                     4e-48)"
                     /gene_kind="transport"
                     /locus_tag="ctg49_14"
                     /transl_table=11
                     /translation="MNLHVKKGRIYGLLGRNGAGKTTTMKMLLGLTKPTSGNIKIFGKS
                     METNSKDILPHIGSLIESPGFYPNLTGTENLRIFAELRGLNKSKCVRDALEVVGLPYRD
                     KKLFAEYSLGMKQRLAIALAVMHNPNLLILDEPINGLDPIGIAEVRSFIRELCDVQGKT
                     ILISSHILSEIELLADDIGIIDKGILLEEESMKELAKKNSRYVNFMVSDSQRAAEILRK
                     EFECDDFQICDKNRLQLYNTTIPRSEITYVFVKQGLEITEVHLCEETLEDYFKRVTGGE
                     GIA"
     CDS             15183..15968
                     /locus_tag="ctg49_15"
                     /transl_table=11
                     /translation="MLKLVKVEFQKLKRKKFILLVTLAAFMFPLPLAYLMTTPAMMEQY
                     IDKADAFDGLFNMILGYGIQFLLPCIIGVVAAMLFFIERDNDTFKNIKTIPLSSTQVVT
                     AKIIVLFIIGVVFCIASTVATVLVGMFTLDVYGLGYKIFLAVETGIFITAGTLPLIVIV
                     VFFSRTYVFSVLLCIFYSVLNMSATALFDALPKTILWLLPTPLTTFWSAGDMKRHGINM
                     NLEQMNGLIPSTFQVILILGIMAGISILLIDCLYKKRGE"
     CDS             15971..16753
                     /locus_tag="ctg49_16"
                     /transl_table=11
                     /translation="MRTIVKTELLKLKRYHIIWAGIALMLLSVLLTLFTSMANDGSVWD
                     FRYLIEQVIKNNMSMIFPMCIALIAGYIISREEKDDVLKNIITIPISFKKLLVGKLIVC
                     AMLSILFGLICTIFTLIAECIVGFPGFTVNLVIQGLVQITLENLFLYLAVLPIIVITSR
                     LSGGFMIGVIVAFVYGYGGMFAAGNMTLANIYPITASLGLIGYRSYDTSVQWSFPLCLC
                     SLIIIVAISVILVATMKEKENKKTRTKTKKVKPKKGWL"
     CDS             16754..17206
                     /locus_tag="ctg49_17"
                     /transl_table=11
                     /translation="MKKSCFFILMFCLLLSGCSKEEVLEKYNAVVEKVGEVQLTNDINL
                     QGKRDYGEDYYTGTYQAEYKKFSDTEYLFGGTTIERAAGKQVELFCNLEITKGEAEIFI
                     ISGSNEPKTLIKTTGTYENTITLPDGSNYIGIVGNDFSGTVKIELK"
     CDS             17440..18102
                     /locus_tag="ctg49_18"
                     /transl_table=11
                     /translation="MKKLFKVFSLMLVVIMAFPFSVMASENDQQRSDLIGAEEGDFEKL
                     IAEIQNIKATHPDYSEEMLMSFLEANHQDVERGIIDIWNALTDSEKKLCIRYPFDALKV
                     NKAKNIATSQTEAKFGTNGLGNRSDAFRHGIWNAEMTVLIGKERAELFATAHEDKDVTG
                     TESDGYPKTAHRDMDLHNNEVGREIGEKNKEASESEMADIIYQEIYSATTSFIWLHE"
     CDS             18238..18612
                     /locus_tag="ctg49_19"
                     /transl_table=11
                     /translation="MESRIKQLREKRGLIQEILAVELGITQQMLSKYERDVTLIKVDIL
                     KKIAAYFNVTTDYLLGVSDVKRDLNGQMKMNEVLDEYYDLVEVYKELDPCDQEMIWSII
                     QIVKKTSEKKKSANMQKRVE"
     CDS             18613..19341
                     /locus_tag="ctg49_20"
                     /transl_table=11
                     /translation="MLNIAICDDDIQITGKIERLLQDIAKRNFVDTEIEVFWNGKSLAD
                     AIAAGERYDVIYLDIEMDKEDGISAARRIRTYDKNVRIIYVTSHESYMRESFEVRPFQF
                     LVKPVTDKIMEKCFKSVYEDINSEDFYFRYSYQRMNHKVPIKDILYFESNKRKIFIVTE
                     QEILELYGKLNEIEETLKTCKISFLRVHQSFLVNYKHISGQSYDSVVMDNGQKISISED
                     RRKIISEQYCSMEDTFYVDE"
     CDS             19328..20638
                     /locus_tag="ctg49_21"
                     /transl_table=11
                     /translation="MWTNRVLMCGIDILLCLWAVYLFFFYFDIFFARKRKRYLSVIGIT
                     LFVIWQFGITTIISFPAYINIAVTIMFTFLAVMMTYEGRWWNKGVFVITFNAIWMLMET
                     LCNYILITYCPQYAAVRQVGSFVSKIFFNAVILALKKVFTDDDIKELPVRYSILLVLIP
                     TGSIYIMNNIFMLGFANNNGRTRINSTFTVLILLGMNILIFYVYMKLADDLRLRRMAAV
                     YEQQLELCERHQQERELSMLQLRDIKHNMKNNLISILAYAENKEYEKMTGFIEEIMGEG
                     GMVIASISNSGNIVIDSLIGYWYVTAQNKKIIFKTDICIPMIMPFKGADLSLILGYLLE
                     NAVEAAEKVEENKYINVKMKFDKNNLLLFVDNSYKGKLLKTRDNRLKSTKSDAENHGVG
                     LASVYRAVAKYHGSVVIEDSEPGKFKIRIVLYSNVQE"
     CDS             20737..21150
                     /locus_tag="ctg49_22"
                     /transl_table=11
                     /translation="MDSVKILLFSDDEKLYNSTERIIGKKHQLKWCTYQQLENNRYPTA
                     DVVIFHFTKEIIERERAFAAIIKIKGSLGHLTPILAISEGGSIQDIFSILKAGAYDYIE
                     TIDNTRKYKKKIENLILWNWYIKKHTSAKKRQC"
     CDS             21292..21441
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_23"
                     /sec_met_domain="TIGR04223 (E-value: 1.8e-16, bitscore:
                     54.3, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSKNLKNQPAKVLANLSLKLGKMSADSACCYIYHQPKMPEALKK
                     MKKL"
     CDS             21446..22027
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg49_24"
                     /sec_met_domain="AgrB (E-value: 3.4e-34, bitscore: 112.2,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKLSEKITRYVIDAGAVSEELYAVYQYGFQIGLEMLICLFVCMS
                     IAIYLHTIPEFLVSTGVFMFLRTYAGGVHLNSFKACFTCSVAVQVMILQINNKYPLGLF
                     VAWGIILVSSICIWKLSPVENINHELEREEKEHCRKVTGKILGVILIAAGCCTTLGMKK
                     YISLIALTALTVFISQCIGIIKYKVEKEKN"
     CDS             22120..22449
                     /locus_tag="ctg49_25"
                     /transl_table=11
                     /translation="MQTVFPEYKSEIVLGNGKFQLDPMSYTVIYEGKEISLAPREFEVL
                     YLLAQRPNWVIPKKNIYCSVWESNYYDDQIPYKTVEHVVWKIRKKMGHDIIETLINVGY
                     RLKKM"
     CDS             22650..23258
                     /locus_tag="ctg49_26"
                     /transl_table=11
                     /translation="MNVYEEIDQETMMLLLDSLCKRTVEGKQIWENMEYNPISFLQKDI
                     YEKEGACISQMFEATTVFNNIEYELELSESIELPSGKGDIFGTISYETEDGKENTYDFS
                     LSFDVEKYDDANAEELQGIFGSSIIVQFTDAIVGIFENSDAVAKGFAYARYYHQTGIDS
                     EWETNPLVKLGEKLMQEHAMLDFHKIVLDTDYRRRLLKQ"
     CDS             23614..24246
                     /locus_tag="ctg49_27"
                     /transl_table=11
                     /translation="MGKQQDREKIVQEIKVAANLYRKHLVGKRFLYVFEGRYIEVLYKA
                     ANFRHLTGVATNLSAKKFYSYAAKKMLQASQIFFTPQHPFSLCKRKIKHIGQIAMLAGS
                     EGFMLEEIVTDTRTYKFGTTDLNFTLCLNKEYDDNGQQKGDCFVVESLRDEDCFSKSRT
                     AYTVTHIFSAPNDAKKYTNLLFLDENATIDGLPDEIKNMLDQTLLHK"
     CDS             24342..24551
                     /locus_tag="ctg49_28"
                     /transl_table=11
                     /translation="MATSSILTELVIEDPKKAEAFINALEMSSQDPVCSPSAPSIPILD
                     SVEEIRRFLERKKQVSLCIGKYLR"
     CDS             24580..24825
                     /locus_tag="ctg49_29"
                     /transl_table=11
                     /translation="MTFSPFLCLNEEIMQCFFVNGAKIVFNSFRYNKSLKPKKERNGNE
                     TGKSCLHSPLPGKGFVIIIEPVINEEIKECRMNFIL"
     CDS             24801..25157
                     /locus_tag="ctg49_30"
                     /transl_table=11
                     /translation="MQNELYIVADAIKALRESRGLTQEQLAEKADISVSHLAKIETHAR
                     AMGMKTYIRLLEAMDIPIKEHFIHMGTAKKDMMLKEKIWYLVQDCDERETSLLIYSIEG
                     IKKGLKKYQQDSRK"
     CDS             25184..25639
                     /locus_tag="ctg49_31"
                     /transl_table=11
                     /translation="MLSREKVEAVLFKMGMPANVKGFGYIVDGVLLLEEDSKIKTTYLY
                     FKVAQQHGTTGQRVERAIRHAFDIVRSCRGDYDVVNHYIGFINCANSPSLSMLTMKIRE
                     EALEVQEPKPEKKEENVITGITEARLLELMRQAYTEFWADMIIRLKK"
     CDS             26279..26824
                     /locus_tag="ctg49_32"
                     /transl_table=11
                     /translation="MKRERLQKLFSEDKEIFQGGMLFPTWICKGKEEIENRNIPQRAAV
                     YLDIPIPCAGLLYYEKEKSLHYCEQQTYQVVTLLEGVGCDYSIEKENWQRLAVLARKGM
                     IDVIVVSGLSRLSYCPEEILQTMEMLQSFQVQIDCIGYGILDYARLKQYLMHTWEKQEQ
                     FEQELDAYLCSCCTRERI"
     CDS             26824..27078
                     /locus_tag="ctg49_33"
                     /transl_table=11
                     /translation="MLSRAELLKMREMTFEDIDPKEIQDVEKLNIDVKKSKPEKIREIL
                     ESGKNPYFLKYKGITIKIGFASTNRTIEEAMQSLVQMKW"
     CDS             27229..28896
                     /locus_tag="ctg49_34"
                     /transl_table=11
                     /translation="MKNQILKKIYRAVVYLRLSDEDGDNRESDSISNQRILIHSFLKSH
                     PEIQVVKECVDDGYTGTNFNRPGFQEMLRMLEEGKADCIIVKDLSRYGRDFSGVLQYVE
                     RILPKMGVRLILVNDNYDSLTPNRDFLTLRFKSLINDLYPADTSKSVRSHLYVKMTAGQ
                     CVAPFAFYGYLKSEEDKHKLVMDEVAASVVRDIYHMKMQGCSLTDISEELNRRGILTPL
                     RYKQVYLKQKLKTGFRLTEKPVWMPTMVRRILLDERYTGVLIQGKTTTPNHKVKVVIHK
                     EEAEWIRYENAFEPVINRHQYEVVGNLMKMDTMRGAKGLALLSGLVKCGDCKESMVLKS
                     PDKVHHYYVCSTSLYEKQCSSHSISEKKLVGAVTEAILHYISVLVELKEILAYVKTASI
                     PRQRLLEEDKKLEMLEKESQRILNIKVKLYDSFAEEILDRTEFETFKAKYDQSLEEIRQ
                     AMECQQREIRNLQETLEKQQEWLEYFLEYRDRTEVDRLMLVNLVKRIEVYEQKRIIIHF
                     WFEDEFEKVLGLLETVNRAKPDRRVEAFLKGKGAEASA"
     CDS             28889..30580
                     /locus_tag="ctg49_35"
                     /transl_table=11
                     /translation="MPKVSKRGQRRQSSKPEVKYLRTYIYVRLSEKDGGHGRRDSIYIQ
                     KQICEDYAKKHPEMLVVKVYADNGVTGTTFQRDAFEELMEDVANKKVDCIIVKDFARFG
                     RDALDAVDLIDVIFPTLNIRFVSVMDEYDSANPACVENRTTNILKHFMNDYYAREVSEK
                     LVQAHRLSRERGEFWGSRPPYGYQRAEENSKKLVPEPEEAEIIRQIFYWYVFEEMSSYD
                     IARELNGRKVLGPEDSYQKRKQGKEPEKRRLWRSDGIRKILQNPVYIGAAVYGKTKQML
                     AQNIPLQMIPKEQWEVCENAWEAVVERAIYEKAQEIAKERWKDTLDNWAANPKEKQGAD
                     GPFKGRIFCGHCGRRLGRSRSGGNEKHKYMVYKCPSFSLTDHTECFRTVNEIYINQAVK
                     AALRYQIQLAVESKKTYGAEFYQKLEQEVAEKIKNARQKYEKYGRKLETLFEHYATGLL
                     DCKEYQEIKSIYQEEQQAARQNMKQIQLRGQHLLDQVKARMDWTEELLKYQRFQKIEKG
                     IADRFIEKITVYSKDYVEIVFWFGDLFEKELEKELDNMEGGLPYAV"
ORIGIN
        1 agtgattata tatacttcat gaaaggagaa agatatataa attatatctg aaagtattat
       61 gttagaaata cttattgcag aaaaaatata taaaacgtat aataattcct ttatagaccg
      121 agtgcactct gaaaaaagaa atgaagtatt aaagggagtt gatttaacag ttggcgaggg
      181 cgaatgcata ggtattatgg ggaaatctgg gtgtggtaaa acgacattgt taaagatact
      241 cggaacaata gagaaagcat ctaaaggtaa aattttattt cagggtgagg acattgaaag
      301 attatctgat gaattgcttt cggaacttag aagaaaaact ttaggatttg tttttcaaga
      361 ttacaaatta cttaatagtt tgactgttaa agaaaatatt attattccaa tggttttaga
      421 gaaaaagaat aagacgtata tagataaaaa aatcagtgag gaagtagaac tattaggaat
      481 ttcatctata ttaaataaat acccatatga aatatctggg ggagagaaac agagggtagc
      541 aattgcaaga gcattggcta atgatcctaa gctaattttg gctgatgaac cgacaggcaa
      601 tcttgattca gcttccgcat taactattat ggatagttta gtaaaggtaa ataagaaagc
      661 aaaaaaagct cttattatag taacgcatga tccattagtg gcaagctatt gtgaaaaaat
      721 attattttta aaagatggca gcattattga ccagattaat tcgcctatag atcagaagca
      781 aaagtataaa aagataatag atacgatgat taatttgtaa gattgagaat taatgttaaa
      841 atttgtaata ataagaatac gataatatta tatactttgg aggaaccaga atgaaaatga
      901 ctttttatat caggatctgt aacagaaggc catcctaaca aaatgtgtga tatgatttcg
      961 atagttaaaa caaagtaata aaagtacaag gtatttaatc tgtgagcatc aaaagaattg
     1021 ctgtatgatg tttagaaagt aaaagtcaaa atgtcaattt ttttaattat aatttaagta
     1081 gcgatttata gttgttttaa atttatataa ataaatgcaa tacaaaaaga tagagttgtt
     1141 acgaggagga acagagatgc aaaatgtttt tccagaatac aaatctgaga ttatactagg
     1201 taatggaaaa tttcagattg atcccatggc atataatgtt atttatgaag ggaaacagat
     1261 tggtttaact ccaagagaat ttgaggtgtt atatttttta gctcagaaac ccaactgggt
     1321 tataccaaag aaaaatattt atcattctgt atggggtatt cattatcatg atgatcagat
     1381 accatacaga acagtagaat atgtgatatg gaagataaga aaaaagatgg gacatgatat
     1441 tatcgaaacg ttggtcaatg tggggtatcg gttgaaaaag ttatagtttt tgggagatat
     1501 aattgagatg aaatagtatg ttattattaa tggaggattt attacatgaa cggaaataag
     1561 aaaagtgcaa aacagtatca ccaatctgta attactgctt tagagaaaaa agtaaatgac
     1621 atgaaagatt ccgcttattc aggattgtat agtgaaatag catttatcat tggaatagca
     1681 gttatcatga tagatacctt ttttccacca gaggaaacga aagttaattg tgtatggaaa
     1741 ataatactga tagctgtatc tatagtctgt atgctttatt tcgccaaaaa agtgaaaaca
     1801 gtgaatgaag tggaagaaga gaaaaagttt tggccgaact tttttattca atgggcaaca
     1861 agtttaggat atataaacat gcctgtagct gtgatagcta ttttggtaac ctttgataag
     1921 ggcaaagcat ggacattatt tatgatgggg gttgctgtaa ttctgacagg tttaacttta
     1981 atagaagcac ttgtaaaaac ttctaaaatt ttaaaaaaag aaaatgttgg taagcggaaa
     2041 taagattgat taaaaaaatt gaggtaaaag gtagacggtg tatttgatat tatttacatc
     2101 tttttgttga aatttgataa tcattttggg tgatgaatat tacatcatta ttattccaat
     2161 ctgctggaaa atacagataa aaggattatg gatatttatc ttgaattcgg atttgaaagc
     2221 caatggacgt ttaaccaggc gtttcagcag aagtatggga ggacacctag caaatatcga
     2281 aaaatatggt gggataattg aatattatga gagttgcaga gaatatatag ggaaatatta
     2341 tttgcggttt gaaagaattt ggagcggata tgcgatttag cgcatatccg cttttgacat
     2401 tgtagaaaag atttttgttt tgaacggtta cgttggtaga cagtaatatt tttatatgga
     2461 agatgtgaaa aaacaaaact attaatattc taacaaaaat tacatagaca gtcgatttta
     2521 ttacatgaat aaaatttcaa gaaataaaag gtgtattatc taaaatgtaa ggaacagaag
     2581 aaaataattc aaccatttca atttagaatt agtatctgta ctgtacaaaa ttgatttatg
     2641 aaaggagaaa taattatgag tgaaatgaga aatcctatta caagagaaga aaactttagc
     2701 aatccagctg gtaacgttat gatggagctg caggaagcag atttaaacaa atttgtagca
     2761 ggagctggtg aaaccagaaa ttccggcgga gttttatgta caagtacagc agaatgctat
     2821 tttggtactt tgctgaaacc ttgctgccct aagaaataaa cacaggtgtt gataaagagg
     2881 gtaagcgtta attgaagttt gtgcagtaca gatacgaatt gtgagttgaa atggaaagca
     2941 gaatggggtg tttaagaaca tgaatactga gagagcatca tattttacag aaagaagtta
     3001 tacaacatca gaagcagaaa ataaaaaaga tatatttgaa tattggaaaa agattttagg
     3061 agaagataca ttaagagttg ctgagaaatg ttatggtatt gatttagtaa aagttttaaa
     3121 ttctgaaaat tatgtatgtg aaaacaatca cgtgatgtca gaaatggaaa aggtaaaaat
     3181 agaattattt gaaaaaccaa tcaattataa ctattccgga ttcaaaggag aaaaattggc
     3241 atttgataat ttttttatac ctttaatcaa ttacggaata gacatattaa aaaatggaac
     3301 aagtcttttt ttgacggatt ctattataga tacatacgca aataccttat tagagagatt
     3361 agggaagatc agtcttggaa tattaatgtt tgaaatgtat ctttgtaaga agacgggaaa
     3421 actgaatgga agaaattcag aggaagaata cgattattat aataataatt ttttaagtaa
     3481 gaaatcgtat aaacaggagc ttttcaatat atatccatgt ttactacgtt cagttacaga
     3541 aaccgtagaa aacttatctt cttattatgt acttttatta gaaagactta ataaagataa
     3601 aaatgaaatt gcgaataaat tttgtggagg tttagaattt aaaaatgtag ttgaaataag
     3661 ttctaatatc tcggattctc ataaaaaagg gaatggggta agtattctta agttggataa
     3721 tggcactaaa attgtgtata aaccacgttc attaaaaatt gaaaaagtgt atttcgattt
     3781 tctgggaaag ataaatgctg gttgtaaata tgagatgtat gaaccaaaaa tattagattg
     3841 tcaggagtat ggttgggagg aatttgtata ttataaaagt tgtaaaacag aggatgaaat
     3901 cagacggtat ttttatagat ttggaatatt gattttcggt agttatattc ttaatacaaa
     3961 tgatttacat gaagaaaatg tgattgccgc aggagaatat ccaattatta tagatgcaga
     4021 aactatacta gataaccgta gaagagggag aacaaattct gcaaaggagg aaataaatta
     4081 tatccttcat gagtcagtat tatactcagg tttattgcca cactataggt tttcaaattt
     4141 gggccaaggc gtagatatga gtgcaattaa aggtagtgag ggaaaggaat atcctatagt
     4201 tattcctaaa atagcggatt tatgtacttc aaatatgaga tttgtatatg aacatcctac
     4261 aactggagta aatcaaaatc ttgttaaatt agatggagaa aatgtatcag catttcatta
     4321 tctaaaagaa ataaatgcag gatttgaaga tgcgtataaa tatgttttgg agaacaaaga
     4381 aaagtttctt gaatatgccg atatgtttgg taatttaaat attcgccatt tagttcagga
     4441 tacccaaaga tattctatgt tattacacac atcttttcat ccggatttta tgcaagatgg
     4501 aagagataga caaatgtttt tgtgtagttt atttaaacag tatgaagcta cacaaggaga
     4561 taaaggtgtt gtgaaatgtg agataaaaga catgttaaac atggacattc catattttta
     4621 tctcaataca tcaggtaaat ctcttttcgg atcagaaggt gagaaaatcg aagactattt
     4681 tgaatatacc agtttggaac acttaaagaa aaagatagta ttgttagatg aagatgattt
     4741 aaaaaggcaa ttaatgttca tgaatattat tctgacagag ataaacgaat ttcaggttga
     4801 ggataaaaag atagagcttc aacaaatgaa aatgattccg cacagagaaa aaaataaggc
     4861 tcatctgtta aaagctgttc agaaattggc tgattctctt ataaaaactg ctgtttttaa
     4921 taaagataga acagaagtta attggattgg tgttactcta ataggaaatg aagatgactg
     4981 ctcatgggat ataagaccac ttggtaccta tttatatgaa ggaatgtctg ggctagcaat
     5041 tttctttaac gcattgtata ctgttgatcc ccaaaaggag taccttatta tatgcaatgc
     5101 gattgaaaag gaattattta catacacaga tgagatgtgt gaacgaaatg agggaataga
     5161 aaatgaaagc agtggcgcct ttggtggaga agcgtctata atgtacactt atgaggtact
     5221 gtataaaatt acaaataaag aaaaatattt ggattatgca aaaaagcact ataaaatatt
     5281 aaagaaagcg attaccagag ataacagttt tgatctggtc tatggtaatg caggcgcagt
     5341 tattacattg atcaatatgt atcagctaac cggaaataaa gagtatatcg cttcggcaga
     5401 aatagcagga gatataatag taaatgctca ggaaaaggaa ggctctatta aaggcggatg
     5461 gaatggagat ggaagaactt cgccgttagc gggattttca catggagcat ctggaatagt
     5521 tttagcactg gcaaaactat ggcaggtgac tcagaaagag gagtatttat tatcactgct
     5581 cgatggcatt aaatttgaaa attctttatt tgtgaaagaa aaaggaaatt ggaaagacga
     5641 aagggtatat gcaggagaaa aagcatctga tggaggaagt tttaccgttg cttggtgtca
     5701 tggcgctgca ggcatattgc ttagccgatc taaagtaaat gtcatattga atgggcggta
     5761 ttcggatttg atagaaaatg atataaaagt agcagtgaat acaatattaa aagagggaat
     5821 tttaggaaac aattgtctat gtcatggtaa tttaggtaat acagaaattt tatttgaata
     5881 tttaaaagac cattcagata aaaagataga aaaatattat gtagatattc gtgatattat
     5941 tgctgagaat gtatgtaatg gtgtatttga ttgcgataat gcgtatctat atggatataa
     6001 attgcaagga tttatgacag gactatgtgg catgggatat tctttgctgc gagatataaa
     6061 aaaagattta ccttgtgtaa ttgctctgga agtctaaaat gatagtattg gaaataatag
     6121 aatttattat ttccaatact aatttattat actagggagg tgtatttatg cacaaaaaaa
     6181 gtgtgccatt gattcgccag atggggacaa cagactgtgg tatagcagca ttgacaatga
     6241 tcttccaata ttataaatat aagatagata ttagtgaatt aaaagctaca acaagtattg
     6301 gaagaaatgg tatgtcttta gcaaaaatga aagaaattac ggaagaacat aatttttcat
     6361 tcaaggcgta tggaaactac gaaaccgaag aaaatttgat aaaatgttta ccgattatca
     6421 tgtgttcaaa agaaaatcat tatgttgtag ttgcggagaa aaaatatggg aaatatatac
     6481 ttttagatcc tttaaaagga aaagaaaagg ttgattattc atatattaaa aagaattttt
     6541 tagatgtact tgtatgtgtt cgaccaacag aaaagaatta taaacgtgag aaacgtgagt
     6601 cttttcttat acctataaat aaaagcaaat tatttctggc aagtattcta acgttggtta
     6661 cacagggaat tatattgatt ccaccgctca ttataaaaaa aatagtcaat gaaataacgt
     6721 atgatacatt aggcttcaat tttgtaaaat atgcgttact gatattatca gtggcattaa
     6781 gttatttact tgcaaattta gctaaaaaaa gggtaatact tattttacag aataatatat
     6841 acaaagatac tatattttta atgctgaata aaatatttga tattgattta agttattttg
     6901 aaagccattc atcaggagat attgaaaatc gctttaatag tgtcagtgat atatacgaat
     6961 ttatatcaac agctctaatt tcaacagtga tagatgtggt tactgctgtt ttttgcggaa
     7021 taatgatgat aacacagtca ataccattgt ttgcagttat aatagtaatg actgttatac
     7081 agataacaat agtaatgatt ttaaatcaaa aagctagaat aaaggttaaa aattatattg
     7141 cagatcagag tgcattacag gcacgaatgg tagaaacttt gactaatatc cagcaaataa
     7201 ggtgcatgag aatagagaat atgctgagtg atagtctgaa acaggattat aagcatttaa
     7261 ttaagagatt acgtgagcgt gtacaaataa gtgatattat ggagtcggtg gtgggggctt
     7321 tttcaatagc ttcttcattg atactttacg ttataggagg atacttggtt tgtgataata
     7381 ggttggaatt aggaacgtta atagcctttg tcacacttgc cggatatttt acaggtccat
     7441 ttcaaactct atctttggtg gtacctcaaa ttaatgtttt aaaggaaaca atgattcgtt
     7501 taaaagagtt aatgaattat aaatctaacc gtaaaaatgg tactcagcat attaattcat
     7561 ttgagtctat ggaaatgcag caagtaacat tttcttacta tggaagcacg aagccagatg
     7621 tagagaatgt tagtatgatg ctaaaaaagg gggagaagat agcatttgta ggaagttcag
     7681 gaagtggaaa gactacaatt acaaaattat tattgaacgt cttttctcat tatcaaggac
     7741 aaattttagt aaacggggaa gatataaaac aaatatgcaa agaggatata gatcggatat
     7801 ttgccatagt tactcaggtt ccaatggcaa tgaatggaac aattagagaa aacgtggata
     7861 ttacaaatac gttgacagat gaggaaatat atcattattt agatttagta gaactgaaag
     7921 atgatataga aaaattccca ttgggactta atacatttgt gggagaaaat ggacagaaca
     7981 tttcaggagg acaaaaacag cgtattgcta tagcaagagc attggcactg aaaccggaag
     8041 ttattatttt tgatgaagcc acaagcaact tagatcctct tacagaacga agaatatgta
     8101 ataatttgaa acaactacat attacccaga ttgtagttac acatagactg aatgccatac
     8161 aagatgctga tacaatatac gtagttgaaa aaggaaaaat aattgaatcc ggaacacatg
     8221 tggaactact tcagttaaag ggagcttatt atgatagtgt aaataattaa gaacaggtga
     8281 aagtcagata atggctttca cctgttcttt taagagatct tttcttcata cggatcaata
     8341 tgttcaatag gtatctctaa tatgaccttt aagccatgag gaagtatatt ttcatatttg
     8401 atatttccgt tatgggcggt taatatttgg taaaccaatt ttagaccaaa tccatgaaca
     8461 gactccccat ttgaattgta catattatta ggaaaaatac cactattcat tttttctatt
     8521 tgtgtagaag tcataccgtc accattatca atgacggaaa taatacaggt atcattttct
     8581 tttaaaattt caactgttat ttcacaacca tgaggattat gattaataca attttgaatt
     8641 agattgctta gcattcttga aaaaagttcc gtatctcctt tgatcaatac tggaatcata
     8701 tcagatgatg aatgaaaatc aaaagaatat ttgttgtcta ttggtccatt cataaagcca
     8761 atgattactt ggcgggcaat ttccacagga gaaaaactgg tttttattaa aggttgcata
     8821 gagtattcta gtcttgaagt taaatttaaa tctgcgatta ggctacggag tttttcgctt
     8881 tgtttacgaa ttatacttgc ttgtagttgt acaggttgcg aagcatcttc atttttttcg
     8941 atttcagaag catatcccaa aataatagaa agaggtgtcc ggacatcatg cgaaacacca
     9001 ttaatccatt cggcacgcgc ctgttctttt tgtagaagat gttttccagc cttatttagt
     9061 tcagcattta tacttgaaag ttcacctgtt tctgaaaggg taatgggttt tccctgagca
     9121 atagagtcaa taccgtcaat gattggcact atagattttt ctattttatg tgtattacgc
     9181 cagaataata taaatatcag taatatatta aaacaaatca ttaaaaagat accgactatt
     9241 aggctgtgaa tataattaat atctattgaa aaattgtatt ttgttatact attaggttcg
     9301 cacccgataa ccaataagcc ggcagaatgt tcttggataa aaacaggata ttcttgtaag
     9361 taccaccgac taaacttggc tatttgtaaa tttgaatagg ttcttggcaa ttcttcgggt
     9421 aaaaattttt cccaaatgac atttccttgt tcgtttaaaa tcatcgccca ggcactttta
     9481 ttttttagag tattttctat ataatcagta gaagaaattg ttccatctac attgagcgtg
     9541 atatttttgc taatggtttg gacgggtata tctggatcag tagaattatt ccatgccatg
     9601 agtaaagtcc cacatattaa aataatattt agtacaaaaa ataaaatcaa tataataagg
     9661 gtggaaagaa gatatttttt aaaaaaacgc ttggcaagct tcattatttt actcctttca
     9721 ctagcaattt ataccctagc cccttaactg ttagcagtga aacaggagaa gaaggatttt
     9781 tttcgatttt ttctcgaaga tgccgaatgt gtgtcatgag ggtagtttca tacccttgcc
     9841 acatttcacc acaagcagtt tggcaaagag ttcctattgt tacaatgtga ttggcattat
     9901 ctacaagttt taataatata ttgtattctt tagcagtcaa aggaataatt ttattttcac
     9961 gatgtatttc tgccttatca atatctataa aagaattttc taattctata attcgtttct
    10021 ctgtaggata acttcttttt aaaatagctt gaacacgtaa caatagttct ttaggcaaaa
    10081 atggtttgat taaataatca tctgctccca attcaaaacc agaaaaacga tcttcggctg
    10141 catctttggc ggtcagcata agaaccggaa gtttactgag ggctctgatt tcttgcaata
    10201 cctcaaatcc gtccatacca ggtaacataa catcaagaat aaccatgtca ggtagagttt
    10261 ctcttattat ttgtaaagcc atttctccag atgttgcggt cattattttt gtatagcctg
    10321 ctctttcaaa tattgtttta ataagggtga gtagttcttg ttcatcatca acgataagta
    10381 taaatttatc atacatatat ttttatctcc taaaatttta tagtttaaat tattatacat
    10441 cttgtggaaa aagaagtata gagaaagagg aaaatctcaa ggttacctca aggttacttc
    10501 aaggaaatct caatgtagtt ggtatataat tacagtataa aaaaaggagg tataaaaaaa
    10561 tgagtgaata tattattcaa accaataatt taacgtaagc gcttaaatct tgggtagctt
    10621 tactgtctac gtttttgaac tcataatgat agtaaataga tttttactac actccgcttg
    10681 ataggagata gaaatttact acatttggag gtttcattat gagtaagaaa cgtgctccag
    10741 ggcgttccct ggacgaatgg atggatctgg taaccgaatg cagacaaagt gngccttatc
    10801 tattaattca ataacatctt tacctaaaat gttattccaa tattctaata tttgagtatc
    10861 tttgattgga acatccttat aataatttct ttcataaaaa taggaattat tgtcacaatt
    10921 atttttatcc ataataatct cctccattac gtaaaaaatt ttgaatttgc atatgatatc
    10981 tatgcataga agccaaacct attcattcag tagtcatcat acctgtggtt tcataccact
    11041 ctcataaact aacagcaaac aaacataatt ggtaagcgct taaatcttgg gtagctttac
    11101 tgtctacgtt tttgaactca taatgatagt aaatagattt ttactacact ccgcttgata
    11161 ggagatagaa atttactaca tttggaggtt tcattatgag taagaaacgt gctccagggc
    11221 gttccctgga cgaatggatg gatctggtaa ccgaatgcag acaaagtggc ctgacagatg
    11281 ctgcatggtg taatgagcat gggatatctc ccagctgttt ttacaatgca gttacccgtc
    11341 tccgcaaaaa agtctgtcag ataccggatc cagttggaaa agccagcact cttgacctta
    11401 catcccataa acaggatgta gtccagattg ctatagaacc ggagtcttct ccggcaggac
    11461 tgatcccaga taatggaaac agacctatgc accttgacaa ttcacatacg attgaaatcg
    11521 aagcagacgg attgcttata cgaatgagta atgagattaa accgttactt ctgaagatgc
    11581 ttatggatac gcttaaggag tcgttatgtt agcggacatc tcaagtgttg atgcaatcta
    11641 tatcgtctgt ggcagaacag atatgcgcaa gtccattgat ggattatgtg cgatcatcca
    11701 ggaacagttt tcgatggaga tcgaccatgc actttttctt ttctgcggtc gtaaatgcga
    11761 ccgtatcaag gctattttaa aagaacctga cgggatcgtt atgatctaca aaagactgac
    11821 cgcccaggga tcttaccggt ggcccaggaa taaatctgag gtccggaatc ttacatggcg
    11881 ggagttcgac tggctgatgt ctggcattga tattgagcag cccaaagcga tcaaggcaac
    11941 ataaaaaaga tgcacataaa actcttgctt tttgctgtat tttcggcact ttcaaggtct
    12001 ggtaaattcg ctgttttgct gggaaaagcc actgttttct ggtataatgg aaacatcaga
    12061 aacaggagga aaaagcagtg gcagacagtt ccaaagatat ccagctccgt gagctgaagg
    12121 acatgataaa cgatctcaaa aagatgataa aaacacttca ggcaactgtc gatgctgcca
    12181 ataaacggga agaagctctc acccaggagc gggataatct gaaagaagag atagaccttc
    12241 tccgcaaaaa actgtttggc acctccagcg aaaaaaggac ccttgatatt ccaggccagt
    12301 taaacttttt caatgaggcg gaactggaac aggatccgaa agctgcagaa gcagaggatc
    12361 ttgaagcaat tcttccggaa aaaacagcaa aaaagcgaaa agcaagagct acagatgcgg
    12421 agcgttttaa gggagttcct gttgaaaaaa agtatctgga actttctgag gaagagaaac
    12481 tctgccctgt ctgtggtatc ccgctgaaag aaatcgggga agagtttgtc cgccgggaac
    12541 tggtctttgt accggcaaaa ctgaaggtat atgaatacta cagtaagagc tatgagtgcc
    12601 cgcagtgcag gcttcaggat attccggtca tcaaaaaagg aaaagatggc agagcccata
    12661 tgctttatgg aatggcttct gccggaacgg ttgcctgggt aatgtaccag aagttttgta
    12721 atggtctccc atactaccgt caggaaaagg actggaaaca gtatggagtg gagatcacca
    12781 gagctactat ggcaaactgg gtgctccgga attccgaagc gttttttctt cctatgtacg
    12841 aatacttcca caggaaactt ctgaaacgtg gattcgtgat ggcagatgaa acgcctcttc
    12901 aggttctgca tgaaccagaa cgccgtgcac agaccaagtc atatatgtgg ctgttccgca
    12961 gcggcgaaga cggaggaccg cctattatcc tctataaata ctcggagacc cgggccgggg
    13021 acaatgccgt agattttctt cacggcttca agggttatct gatgtgtgat ggctatagcg
    13081 gatacaataa agtaccggat gccaaacgca cagcctgctg ggcacacatc agaagatatc
    13141 tgacagatgc catccctaag ggaaaggcgc tggattatac ccagccatcc gtacagggaa
    13201 tgctgtacat taaccagctc ttccatctgg aagatgtgat cagatcaaag tattcttcct
    13261 tcgatgctat taaaaaggct cgccttgaaa aagaaaagcc ggtagtagaa ggctttttgt
    13321 cgtggcttga tcagcagaac cctatccgtg gaagcagaat ggacaaagct gtcacctaca
    13381 ttcagaatcg ccgctcctat ctgtccacct atctggaaga cggccgctgc agtttttcta
    13441 ataatctcag tgaaaatgcg attcgcccat ttacagtagg tcgtaaaaac tggctgttct
    13501 gtgatacacc aaacggagcc caggccagcg ctatcgtgta cacaatggta gaaatggcaa
    13561 aagccaatgg agtaaacgtc tatcactatc ttacctatct gctggaaaaa ctgcctgatg
    13621 acaggatgag tgatgatgaa ttagaacttc tggcgccatg gaacgaaacc gtcaaagctg
    13681 aaatcgaacg tcgtgcaaac gaatcaaatc aatcatatgt gaattgtcaa ggtgctccgg
    13741 ctactgaaaa gtagtcgggg atttttttat cataccaaaa aattaagcgc ttaccataat
    13801 tgttccccag ttacattctt ttgttgatgt acagaactga gagccatcgg aaactcttgg
    13861 ttcaccagca cctgcggaaa aattgtttaa atccgcctct ttaatttcct tcattacatt
    13921 tcctgccgga ttcataaaat tttctggtct tgtcattgga tttctataat ttttcttcat
    13981 aaggcacgct cctaactgct tcttgcatag ataccatatg taaattcaaa atgtctatat
    14041 ctatacgatt taatttttca caaaatactg caggaataca gaacccttca ggttcatcct
    14101 aagnaaaaac tgcctgatga caggatgagt gatgatgaat tagaacttct ggcgccatgg
    14161 aacgaaaccg tcaaagctga aatcgaacgt cgtgcaaacg aatcaaatca atcatatgtg
    14221 aattgtcaag gtgctccggc tactgaaaag tagtcgggga tttttttatc ataccaaaaa
    14281 attaagcgct tacaatttaa caaaacagta tggagagcaa aagagtgttt ctgcaatgaa
    14341 cttgcatgtg aaaaaaggaa gaatttatgg actgttggga cgtaatggag caggaaaaac
    14401 gactacaatg aaaatgctgt taggattaac aaaaccgaca tcgggaaaca taaaaatatt
    14461 tgggaaaagt atggaaacca atagtaaaga tattttaccg catataggta gtttaataga
    14521 atcaccagga ttttatccta atttgactgg gactgaaaat cttcgtattt ttgcggagct
    14581 tagaggatta aataaaagta agtgtgtaag agatgctttg gaagttgtcg gtttgcccta
    14641 tcgtgataaa aagttatttg cggaatattc acttgggatg aaacaacgac tggccattgc
    14701 attggcagtt atgcacaatc ccaatttgct gatattagat gagcctatta atggtttgga
    14761 tcctataggt attgcagagg tacgttcgtt tattagagag ttatgtgatg ttcagggaaa
    14821 aactattttg atttctagtc acatattatc agagatagaa ttactggcag atgatatagg
    14881 gattattgat aagggaattt tacttgaaga agaaagtatg aaagaattgg cgaaaaaaaa
    14941 tagtcgctat gtcaatttta tggtatcgga tagccagcgc gcagcggaaa ttttaagaaa
    15001 agaatttgaa tgtgatgatt ttcaaatatg tgataaaaat agacttcaat tatataatac
    15061 aacaatccct agatcagaaa ttacttatgt ttttgtaaag caaggattgg aaattacaga
    15121 agttcattta tgcgaagaaa cattggaaga ttattttaaa agggtgaccg gaggtgaagg
    15181 aattgcttaa attagttaag gttgaatttc aaaaactgaa aagaaaaaag tttattcttt
    15241 tagtaacttt agctgcattt atgtttccgc ttccattggc ttatttaatg acaacaccag
    15301 ctatgatgga gcaatatatt gataaagcgg atgcatttga cggactattc aatatgatat
    15361 tggggtatgg aatccaattt ttattaccct gtattatcgg agtagtagct gctatgttgt
    15421 tttttattga acgtgataat gatacattta aaaatattaa aacaatccca ttatccagta
    15481 cgcaagtagt tacagcaaaa attatagtgc tatttattat aggcgttgta ttttgcatag
    15541 catcaacggt agcaacagtt ctggttggta tgtttacgtt agatgtatac ggtttaggat
    15601 acaaaatatt tctggcggtt gaaacaggaa tatttattac cgctggaaca ttaccattga
    15661 ttgttatagt ggtatttttt agtcgtactt atgttttctc tgttttatta tgtatttttt
    15721 atagcgtttt aaatatgagt gcaacagcac ttttcgatgc attacctaag acaatattat
    15781 ggttacttcc tacgccgctt acaacatttt ggagtgctgg agatatgaaa agacatggaa
    15841 ttaatatgaa ccttgaacaa atgaatggat taattccttc aacttttcaa gtaatattaa
    15901 ttcttgggat tatggcagga atttcaatac tattaattga ctgtttgtac aagaaaaggg
    15961 gggaataaaa ttgaggacta ttgtaaaaac cgaattattg aaattaaaac gttatcatat
    16021 tatatgggcg gggatagctc ttatgctact ctctgttcta ttgacacttt ttacttctat
    16081 ggctaatgat ggatctgtat gggattttcg atacttaata gagcaggtaa tcaaaaataa
    16141 tatgtcaatg attttcccaa tgtgcatagc tttgattgct ggatatatta tatcgcggga
    16201 agaaaaagac gatgttttga agaatattat taccattcca atttcattta aaaagttgtt
    16261 ggtaggaaaa cttattgtat gtgcaatgtt atcaatatta tttgggctta tttgtacaat
    16321 atttacgtta attgcagaat gtatagttgg ttttcctgga tttacagtaa atttggtaat
    16381 tcaaggatta gtacaaataa cattggaaaa tttatttttg tatctagcgg tattaccaat
    16441 tattgttata acaagcagac tatcaggcgg ctttatgata ggtgtcattg ttgcttttgt
    16501 gtatggatat ggaggtatgt ttgcagcagg aaatatgaca ttggctaata tatatcctat
    16561 tactgcaagt ctgggattaa ttgggtatag aagttatgat acatccgtac aatggagttt
    16621 tccattgtgt ttatgtagct tgataattat tgtcgctatt tctgtaattt tagtcgcaac
    16681 aatgaaagaa aaggagaaca aaaaaactcg tacaaaaaca aaaaaagtca aaccaaagaa
    16741 agggtggtta taagtgaaaa aaagttgttt ctttattcta atgttttgct tgttattgtc
    16801 tgggtgttca aaagaggagg tgttggaaaa atataatgca gtagtcgaaa aggtgggaga
    16861 agtacaatta accaatgata taaacctgca agggaaaaga gattatgggg aagattatta
    16921 tacggggaca tatcaagcag agtacaaaaa attttctgat acagaatatc tttttggagg
    16981 aacaacaata gaaagagcgg cagggaagca ggttgaattg ttttgtaacc tagaaataac
    17041 aaaaggagaa gctgaaatat tcattatttc tggtagcaat gaacctaaaa ctttaataaa
    17101 aacaacaggt acttatgaaa atacaataac attaccagat ggcagtaatt atatcgggat
    17161 tgtaggtaat gatttttcag gaacagtaaa aatagaattg aaataaagat agaaaatgct
    17221 aaaaatgggt aaatttggaa gataccggtt tggttgcatt ttactgtggt aaaaagtata
    17281 tgaagagtgg aatggcggtt gtttaatact gccattcttt tttttgaaaa tgcctctatg
    17341 ggaattatta cacagggaat cgaaaaaatt acatgtagat gggatagtac attaaatatg
    17401 gtaaaatata atcataatat gagatcggag gtatattcta tgaagaaact atttaaagta
    17461 ttcagcctaa tgctggtggt gataatggct tttccattct ctgttatggc aagcgaaaat
    17521 gaccagcaaa gaagtgattt gattggtgca gaagaagggg attttgaaaa attgattgca
    17581 gaaatccaga acattaaggc tactcaccca gattattcag aagaaatgct catgtctttt
    17641 ttggaagcca atcatcaaga tgtggaaaga gggattatag atatttggaa tgcgcttaca
    17701 gattcagaaa agaaactatg tattcgttat ccttttgatg ccctaaaggt aaataaagca
    17761 aaaaatattg ctacttcgca gacagaggca aaatttggga caaatggttt aggaaacaga
    17821 agtgatgctt ttcgtcatgg aatttggaat gcagaaatga ctgttttaat aggaaaagaa
    17881 agagcagagt tatttgcaac tgctcatgaa gacaaagatg ttacaggaac agaatcagac
    17941 ggatatccaa aaacagcaca tagagatatg gacttacata acaatgaagt gggaagagaa
    18001 ataggagaaa aaaataaaga agcttctgaa agtgaaatgg cggatattat ttatcaggaa
    18061 atatattccg caacaacatc atttatatgg ctacatgaat aagatttgag cagtgcgatc
    18121 gcactgctcg tcttcgtatt ttgcatattt tgcgtaattg attacttcta ttatttgtat
    18181 cgctatgaat gaaatagggc agcatgatag tacaacatga ttaagaggta ggcaattatg
    18241 gaaagtcgta ttaaacaatt acgtgagaaa agagggttaa tacaggaaat ccttgcagta
    18301 gaattaggga taacacagca aatgttgagt aagtacgaaa gagatgttac gttaataaaa
    18361 gtagatattc tgaaaaagat tgctgcttac ttcaatgtaa caacagatta tttgctggga
    18421 gtttcagatg taaaaagaga tttgaatggg cagatgaaaa tgaacgaagt actagacgaa
    18481 tattacgatt tagtggaagt gtataaagag ttagatccat gtgatcagga gatgatttgg
    18541 tcaattatac aaatagtaaa aaaaacgagt gagaagaaaa aatcagcaaa catgcagaag
    18601 agagtggagt gaatgttaaa tatagcaatt tgtgatgatg atattcaaat aactggaaaa
    18661 atcgaaagac ttctccagga tatagctaaa agaaattttg ttgatactga aatagaagta
    18721 ttctggaatg gaaagagttt agcagatgct atcgcagcag gtgagaggta tgatgttatt
    18781 tatctggata tagaaatgga taaagaagat ggtatttcgg cagctagaag aattagaaca
    18841 tacgataaaa atgtgcgaat tatttatgtt acgagccatg aaagttatat gagggaatcc
    18901 tttgaggtaa gaccgtttca gtttcttgta aaacctgtaa cagataaaat aatggaaaag
    18961 tgctttaagt cggtatatga agacattaat agtgaagatt tttattttcg ctatagttat
    19021 caacgtatga atcataaagt accaatcaag gatattttat attttgaaag caacaaacga
    19081 aaaatattta ttgtaacgga acaagaaatc cttgaactgt acggaaaact taatgagatt
    19141 gaagaaaccc ttaaaacatg taaaatttct tttttgcgag ttcatcagtc ttttctggtg
    19201 aattataaac atatctccgg acaatcttat gattctgtag taatggataa tggacaaaaa
    19261 atttcaatca gtgaagaccg gagaaagata attagtgaac aatattgttc tatggaggat
    19321 acgttttatg tggacgaata gggtattaat gtgtgggata gatatattgc tttgcctttg
    19381 ggcagtatat ttattctttt tttatttcga tatatttttt gctcgtaaga gaaaaaggta
    19441 tttgtcggtg atcggtataa cgctgttcgt gatttggcaa tttggaataa caacgattat
    19501 tagttttcct gcctacatca atattgctgt gacgattatg tttacgtttt tggcagttat
    19561 gatgacttat gaaggtagat ggtggaacaa aggtgtattt gtaattacct ttaatgcgat
    19621 ttggatgttg atggaaaccc tgtgcaacta tattttgata acatactgcc ctcaatatgc
    19681 tgcagttcgc caagtaggct cttttgtttc aaaaatattt tttaatgcag taattcttgc
    19741 attaaagaaa gtgttcacag atgatgatat taaggaattg ccggtcagat acagtatttt
    19801 acttgtgttg atcccaacag gaagcattta tatcatgaac aatatattta tgcttggatt
    19861 tgcaaataat aatggacgta ctcgtataaa ctctacattt actgtactta ttttacttgg
    19921 tatgaacata ttgatatttt atgtctatat gaagttggct gatgatttgc ggttaaggag
    19981 aatggcagca gtatatgaac agcaactgga attatgcgaa cgtcatcagc aagaaagaga
    20041 actttcaatg ttgcagttgc gggatataaa acacaatatg aagaataatc ttatttccat
    20101 tcttgcttat gcagaaaata aagaatatga aaaaatgaca ggttttattg aagaaattat
    20161 gggagagggc ggtatggtga ttgcctcaat atcgaatagt gggaatattg tgattgattc
    20221 acttattgga tattggtatg taactgccca aaacaaaaaa ataattttta aaacggatat
    20281 ttgtattccg atgataatgc cttttaaagg agctgatctg agtctgatat tgggatattt
    20341 actggaaaat gcagtggaag cagcagagaa ggttgaagaa aataaatata taaatgtcaa
    20401 aatgaaattt gataaaaata atctattatt gttcgtagac aatagttata aagggaagct
    20461 gttaaaaaca agagataacc gcttgaaatc tacaaagtca gatgcagaaa atcatggagt
    20521 aggtttagcc tctgtgtatc gggcagtagc aaaatatcat ggatcagtgg taatagagga
    20581 ttcagaacca ggaaaattta aaattcggat agtcttatat agtaatgtgc aggaataatt
    20641 acatgaacac tcgaaataat tacataaaaa ataatgagaa aggaaagaat ggtaaaatgg
    20701 aaagataaat ttggtatgcg gtatggggac tgatatatgg atagtgtgaa aatattgctg
    20761 tttagtgatg atgagaaact gtataacagt actgaaagga ttattgggaa aaaacaccaa
    20821 ttaaaatggt gtacttatca acagttggaa aacaatagat atccaacggc agatgttgtg
    20881 attttccatt ttactaaaga gataatagag agggaaaggg catttgcggc tattataaaa
    20941 ataaaaggga gtttggggca tttaacgcct attcttgcta ttagcgaagg gggatcaata
    21001 caggatattt tttctatact gaaagcagga gcttacgatt atatagaaac aatagataac
    21061 acacgaaaat ataagaaaaa gatagagaac ctgattttat ggaattggta tataaaaaaa
    21121 catacatcag caaaaaagag gcaatgttga gaaagaaccg gagaaacatt gcttcttttt
    21181 ttctgccttt ttgggaaaaa ttacatcaat actcggtttt tttacaagag aaccgaatgg
    21241 gagatttttt gtagtaatgt attggtaaac aaatgaaagg agattttaat tatgaaatct
    21301 aaaaatttaa aaaatcagcc agcaaaagta ttagcaaatt tatctctgaa acttggtaaa
    21361 atgtcagcgg acagtgcttg ctgttatatt tatcatcagc caaagatgcc agaagcattg
    21421 aaaaaaatga agaaacttta attttatggg aaaattatcg gaaaaaataa caagatacgt
    21481 tattgatgcc ggtgcagttt cagaggagtt gtatgcagta tatcaatatg gatttcagat
    21541 tggattagag atgttaattt gcctattcgt ctgtatgagt atagcgatat acttgcatac
    21601 aatcccagaa ttccttgtgt ctacaggtgt ttttatgttt ttaagaacct atgccggtgg
    21661 tgtacatctg aatagcttta aggcttgttt tacatgctct gttgctgttc aagtcatgat
    21721 tttacaaatt aataacaaat atccattagg gctatttgtg gcttggggga ttattttggt
    21781 aagttccatt tgtatatgga aactttctcc tgtagaaaac attaaccatg agttggaaag
    21841 agaagaaaag gagcattgcc gaaaagtaac aggtaaaata ctaggagtta ttttaattgc
    21901 tgctggttgt tgtacaactt taggtatgaa aaagtatata tccttgattg cgttgacagc
    21961 gttgaccgtt tttatatcac aatgtatcgg tatcataaag tataaagttg aaaaagagaa
    22021 aaattagcgg gaatgatagg ggtctattat ttccgcattt ttattgtgtg tatagttttg
    22081 aactattgct gggatagaaa atcatggagg tgaaaatgaa tgcaaaccgt ttttccagaa
    22141 tataaatctg aaattgtatt aggaaatggt aaatttcaac ttgatcccat gtcatatact
    22201 gttatttatg aaggaaaaga aatcagctta gctcccaggg aatttgaagt tctgtatctt
    22261 ttagcccaaa gaccaaattg ggttattcca aagaagaata tctattgttc ggtctgggag
    22321 agtaattatt atgatgatca gattccgtac aaaacagtgg aacacgtagt atggaagata
    22381 cgaaaaaaga tggggcatga tattatagaa acattgatca atgtaggata tagactaaaa
    22441 aagatgtaaa ggcgagatag tgtgagtaag cggtgtgagt aaaagtttgt atattctgat
    22501 tgaattttta ggagatatgc catataatat tggcaactat aagaaggcgc gtacatacgt
    22561 catttgacta aatatcacgt tgtaactaga aattgagata aactcttaca gagcttttgt
    22621 ggactatcca aagaaaaagg aggctgacta tgaacgtata tgaagaaata gatcaggaaa
    22681 caatgatgtt gcttttagat tccttgtgta aacggacagt ggagggaaaa cagatatggg
    22741 aaaatatgga gtataatcct atttcctttt tacagaaaga tatttatgaa aaagaaggtg
    22801 cctgtatatc acaaatgttt gaagcaacga cagtgttcaa taacattgaa tatgaattag
    22861 agctttcaga gtcaatcgaa cttccgtctg gcaagggaga tatttttgga acaatttctt
    22921 atgaaacaga agacggaaaa gagaatacgt atgatttctc tttgtctttt gatgtagaga
    22981 aatatgatga tgcgaatgcg gaagaattgc aggggatttt tgggagctca atcattgtac
    23041 agtttacaga tgcaatagtg ggaatatttg aaaattcaga tgcggtagct aagggatttg
    23101 cttatgcaag atactatcat caaacaggaa ttgattcgga atgggaaacc aatcctcttg
    23161 tgaaacttgg tgagaaactg atgcaagagc acgcaatgct ggattttcat aaaatagtat
    23221 tggatacaga ttatagaagg agattattaa aacagtaatt aacgtgataa aacaggatac
    23281 aaatttgggg aaactattga tatttcttag ggtatcgcat ataatatagt taagccaaaa
    23341 ggtttcgtgt agcggcacgt aaaagctgta ctgtgcccgg gcagggtaat tactgggact
    23401 atttgatact cggaagggta ttacgcccac accagggaga tacggtgagt ccgcgccggg
    23461 gactcaatga taccggcgac attttagaca ttcggaagga tgtcgcggct gacagccagc
    23521 ataaaaccgc tttttaagat tatgggcgct ggataacaaa aaagttgtcc agtgctgttt
    23581 ttttatacta tagtgatgat tgggaaaaga tagatgggaa aacaacagga tagagagaaa
    23641 attgtacagg agattaaagt ggctgctaat ctgtatagga agcatttagt aggtaaaaga
    23701 tttctatatg tatttgaagg cagatatatt gaggtgcttt ataaagctgc caattttagg
    23761 cacttgacag gtgtggccac gaacctttca gcaaaaaagt tttatagtta tgcagcaaaa
    23821 aagatgcttc aggcttcgca gatatttttt acaccgcagc accctttttc attgtgtaag
    23881 cgtaagatta agcatatcgg acagattgca atgctggctg gctcagaagg atttatgctg
    23941 gaagagattg tcacagacac gagaacttat aagtttggca caacagatct taattttact
    24001 ctatgcttaa ataaagagta tgatgataat gggcagcaaa agggcgattg ctttgtagta
    24061 gaatcgctgc gagatgaaga ttgcttttct aaaagtagaa cagcatatac agtaactcat
    24121 attttttcag cgccgaatga tgcgaaaaaa tatacaaatt tattgttttt agatgaaaat
    24181 gcaacgatag acggtcttcc agatgaaatt aaaaacatgc tggatcaaac tttattacat
    24241 aaataaaaat ggagcgtaca ggtcttggcg tatagaaaat actgcaggat cttcttacga
    24301 aagaattttt taagatatga gagaaaagag gtgctttcta tatggctaca tcaagtatcc
    24361 ttacagagct tgtgattgaa gaccccaaaa aggcagaagc atttattaac gcactggaaa
    24421 tgtccagtca agatccagta tgcagcccgt ctgccccgtc cattcccata ttagatagtg
    24481 tggaagagat acggaggttc ctggaaagaa aaaaacaagt aagcctatgt attggcaaat
    24541 atcttagatg aatagaagct ataggagagg agtcgatatg tgacgttctc tcctttttta
    24601 tgcctaaatg aagagataat gcagtgcttt ttcgtaaatg gtgcaaaaat cgttttcaac
    24661 tcgttcagat ataataaatc tctaaaacca aaaaaggaaa gaaatggtaa tgaaactggg
    24721 aaatcttgcc tccatagtcc attaccaggg aaaggatttg taattataat agagcctgta
    24781 atcaacgagg agataaaaga atgcagaatg aactttatat tgtagcagat gctataaaag
    24841 ccttgcggga atccagggga ctgactcagg agcagcttgc agagaaagcg gatatttctg
    24901 tatcccatct ggccaaaatc gaaacacatg ccagagctat gggtatgaaa acctatatcc
    24961 ggctgttgga agctatggat attcccataa aagaacactt tatacacatg gggacagcga
    25021 aaaaagatat gatgctgaaa gaaaaaatct ggtatctggt acaggattgt gatgaaaggg
    25081 aaactagcct tttgatttat tccatagagg gaattaagaa agggctaaag aaatatcagc
    25141 aagacagcag gaagtgagaa tacagatagg gaggaaaagg gaaatgttat caagagaaaa
    25201 ggtggaagca gtattattta aaatgggaat gcctgccaat gtaaaaggat ttggttatat
    25261 cgtagacggt gttttgcttc tggaagaaga cagcaagatt aaaacgacat atctgtattt
    25321 taaggtggcc cagcaacatg gcacgacagg acagagggta gaacgggcaa tccgtcatgc
    25381 gtttgatatt gtccgaagtt gcagaggtga ttatgatgtg gtgaaccatt atatcggttt
    25441 tatcaactgt gccaattccc cttccttatc catgcttacg atgaaaatac gggaagaagc
    25501 actggaagta caggaaccaa aaccggaaaa gaaagaagaa aatgtaatta caggaattac
    25561 cgaagcccgg cttctggagt taatgcggca ggcatacaca gaattctggg cagatatgat
    25621 tatccggtta aagaaataaa gagaaatgca gacagaaaac agtctgccaa aacacatcag
    25681 ggttatggtg tcttttggca ggctgatgtt ttcagccgga gagaaccttg aaaactgaat
    25741 atcggtatgg tgatattttt ttgaaacaaa cgtgtcattt ctgacgctaa aatatagaaa
    25801 tatcttaaag gacacaaaac atttcggcac attctatttt gtgtgatgca gggtcatgag
    25861 ctgtgcgaag atacatttgt ccgcagtggc agcaggtaag gcagaaaaga agcggatcaa
    25921 acaaggaatc gtagaagatg aaggaaaagt gtgagcagcg cccagacata ggctgttggt
    25981 ggcaggcagc ctgaaagccg aatgataatg atacctttgc ataaaaacac tgcaaccagg
    26041 gtagcgtctg ggacatgctg tagcgagaaa gggggctgca gggtgtcagg cggccagccg
    26101 ggccggtcct acatgctccc gttcacaccg gggtgagaaa atgaaaaaat catgctggca
    26161 gggaaagccc tgccggtatg gtgtgtgaaa caggttcatt ttagggctat ggggaaacaa
    26221 caggtttcct tatagccctg gaatgaaaac aggagcaaaa gaaagaggag gcagagcaat
    26281 gaagagagag aggttacaga aactgttttc agaagataaa gagatctttc agggaggaat
    26341 gctgtttcct acatggatct gcaaaggaaa agaagagata gaaaatagga atattcccca
    26401 gcgtgcggca gtgtatctgg atattcccat tccctgtgcc gggcttttgt attatgaaaa
    26461 agaaaaaagc ctacattact gtgaacagca gacataccag gtggttactt tgttggaagg
    26521 tgtagggtgt gattattcca tagaaaaaga aaactggcag aggctggcag tgcttgcacg
    26581 aaaaggcatg attgatgtga ttgtggtatc cggactcagc aggttatcct attgtccgga
    26641 agaaatttta cagacaatgg aaatgctcca gtctttccag gtacagatag actgtatcgg
    26701 ttatgggatt ttagattatg ccagactgaa acagtattta atgcacacct gggagaaaca
    26761 ggaacagttt gagcaggagt tagatgcgta tctgtgcagc tgctgtacta gggaaaggat
    26821 ataatgctct cgcgggcaga actgctgaag atgagggaaa tgacatttga ggacattgac
    26881 ccgaaagaga tacaagatgt agagaaactg aatattgatg taaaaaagag caaaccggag
    26941 aagatccggg aaatcctgga gtccggaaag aacccttatt ttctgaaata taaggggatc
    27001 accataaaga ttgggtttgc ttctaccaac cgtaccatag aggaagccat gcaaagcctt
    27061 gtgcagatga aatggtaaag ccacgacagg gatagggaac aaagcggatt gttggcagat
    27121 tacagggtgg acaaaccttc tggactatgg taggatgatg gcaaggaccc agtagcctct
    27181 atcatttagg gaatcggctg acgaatctaa atgataggag cgaatacaat gaaaaatcaa
    27241 atacttaaaa aaatctatcg tgcggttgtt tacctgcgcc tttctgacga agatggtgat
    27301 aacagggaaa gcgacagcat atcaaaccag aggatactaa tccatagctt cttaaagagc
    27361 caccctgaaa ttcaggtggt aaaagaatgt gtagatgatg gatataccgg cacaaacttt
    27421 aaccgccccg gttttcagga aatgctgcgt atgctggaag aggggaaagc agactgtatt
    27481 attgtcaaag acctttcccg ttatggaagg gacttttccg gtgttttaca gtatgtggaa
    27541 cgtatcctgc cgaaaatggg tgtgcgcctg atccttgtca atgacaatta tgacagcctc
    27601 acgccaaatc gtgatttcct taccctgaga tttaaaagtt taatcaatga cctttatcct
    27661 gcggatacct ccaaaagtgt gcgctctcat ttgtatgtca aaatgacagc cgggcagtgt
    27721 gtagcgcctt ttgcttttta tggttatctg aaatccgaag aggataaaca taagctagtt
    27781 atggacgaag tggctgcttc tgttgtacgg gatatttacc acatgaaaat gcagggctgc
    27841 agcctaacgg atatatccga agaattaaac cggcgtggga tcttgacgcc tcttcggtat
    27901 aagcaggtat atttaaaaca gaaattaaag acagggttcc gcttgacgga aaaaccggtc
    27961 tggatgccaa ctatggtacg ccgtatcctt cttgatgaac gctataccgg agtgctgata
    28021 cagggaaaaa caacaacgcc aaaccataaa gtaaaggttg tgatccacaa agaggaagcc
    28081 gagtggatac ggtatgaaaa tgcctttgag ccggttatca acagacatca atatgaagtg
    28141 gtaggcaacc tgatgaaaat ggataccatg aggggtgcaa aggggctggc gcttctttcc
    28201 ggcctggtaa aatgtgggga ctgtaaagaa agcatggtac tgaaaagccc ggataaagtc
    28261 caccactatt atgtatgttc gacttccctt tatgaaaagc agtgcagttc ccatagtatc
    28321 agtgagaaaa aactggtagg agctgtgaca gaggcaatcc tgcattatat ttctgttctg
    28381 gtggagctga aagagatact ggcgtatgta aaaactgcct caatcccaag acagcggctt
    28441 ttggaagaag acaaaaaact ggagatgctg gaaaaggaga gccagaggat tttaaacatt
    28501 aaagtaaaac tgtatgacag ttttgcagaa gaaatcctgg accggacaga atttgaaacc
    28561 ttcaaagcaa agtatgacca gtctttagag gaaatccggc aggcaatgga gtgccagcaa
    28621 agggaaatcc gaaacttgca ggaaaccctt gaaaaacagc aggagtggct ggaatatttt
    28681 ctggaatacc gggaccggac ggaagtggac cgcttaatgc tggtaaatct ggtcaagcgg
    28741 attgaggtat atgaacagaa gcgcattatc attcattttt ggtttgaaga tgaatttgaa
    28801 aaggtattgg gactgctgga aacggtaaac agggcaaagc cggaccggcg tgtggaagcc
    28861 ttcctgaaag gaaagggggc ggaagcaagt gcctaaggta agcaaaagag gacagagaag
    28921 acaaagcagc aagccagaag ttaagtatct gagaacctat atttatgtaa ggctttccga
    28981 aaaggacgga gggcatggca gaagggattc catttatatc caaaaacaga tctgtgaaga
    29041 ctacgcaaag aaacacccgg aaatgctggt ggtaaaagtc tatgcggata atggtgtgac
    29101 aggtacaacg ttccaaaggg acgcatttga agagttgatg gaagatgtgg caaataaaaa
    29161 ggttgactgc atcattgtaa aggattttgc ccgttttgga agggacgcct tagatgctgt
    29221 agatttgatt gatgtgattt tcccaacctt aaatatccgg tttgtttccg ttatggacga
    29281 atatgacagc gcaaacccag cttgtgtaga aaacaggacc accaatattt tgaaacactt
    29341 tatgaatgat tattatgcca gggaagtttc agagaaactg gtacaggcgc accggctgtc
    29401 cagggaacgg ggagagtttt ggggttccag acctccttat ggataccaaa gagcagagga
    29461 aaacagtaag aagctggtgc cggaaccaga ggaagcagaa ataatccggc agatttttta
    29521 ctggtatgtg tttgaagaaa tgtcaagcta tgatatagca agggaactga atggcagaaa
    29581 ggtattagga ccggaggaca gctaccagaa aaggaaacag ggaaaggagc cggaaaaaag
    29641 gcggttatgg agatcagacg gtatcaggaa gattttacag aaccccgttt atataggtgc
    29701 tgctgtttat gggaaaacaa aacagatgct tgcgcagaat attccccttc agatgatacc
    29761 aaaagagcag tgggaagtgt gtgaaaatgc ctgggaagca gttgtggaac gggcgattta
    29821 tgagaaagca caggaaattg caaaggaacg ctggaaagat acgttggata actgggctgc
    29881 aaacccaaaa gaaaaacagg gggcagatgg cccttttaag ggaaggattt tctgcgggca
    29941 ttgcggaaga cgtcttggaa ggagcaggag cggaggcaat gagaaacaca aatatatggt
    30001 ttataaatgc ccttcctttt cccttaccga tcatacggaa tgtttccgga cggtgaatga
    30061 aatctacatc aatcaggcag tcaaggcagc actccgctac cagatccagc ttgctgtaga
    30121 aagtaagaaa acctatggtg cagagtttta tcaaaagctg gagcaggagg tagcagaaaa
    30181 aataaaaaat gccagacaga agtatgagaa atatggaaga aaactggaaa ccttgtttga
    30241 gcattatgct accgggctgt tggactgcaa ggaatatcag gagattaaat caatctatca
    30301 ggaagaacag caagcagcca ggcagaatat gaagcagata cagcttcgtg gacagcacct
    30361 gttagatcag gtgaaggcaa gaatggattg gacagaggaa cttctaaagt accaaagatt
    30421 tcagaagata gagaaaggaa ttgcggaccg ttttattgaa aagattacgg tatattccaa
    30481 agactatgtg gaaatcgtgt tctggtttgg ggatttattt gaaaaggagc tggaaaaaga
    30541 actggacaat atggaaggag gtcttccgta tgcagtgtga ttttgttttt gcttatctgc
    30601 gtctttccag agatgataaa gaaaaaatgg aggaaagcaa cagcattaaa aatcaaaggc
    30661 ttttaattca gcactttgta gaaaaccagc cggagtttgc aggggcaaag cttttcttct
    30721 ttgtagatga cggttacagc ggtacaacgt ttgaccgccc ggaatttaag cgcatgatgg
    30781 ggctgattac caggagaaaa cggatctgta tcattgtcaa agatttgagc cgcctgggaa
    30841 gggataccat agaaacacaa aactatatcg aaaaaatatt tccgttcctt ggggtgcgtt
    30901 tcatttcaat caatgatttt tatgacagca gccagaaacc ttccgaaaga aaggatacgg
    30961 agattaaatt taagaacctg atcaatggga tttatcccca gatttgttcc gacaatatca
    31021 aaaaagttat gaggaaacag gctgaaatgg gacaatatca tggttcaatc ccaacatacg
    31081 gatattgctt ccatgacggt gttcatacaa aacttcatct ggatatggag gcagcttccg
    31141 ttgtaagggg gattttcgac caaaggttgg aaggaaagac ctatgcagac attgccaggg
    31201 acctgaataa aaaagaagtt gaaacaccta ccgtatatct tcaaaggaaa ggctgggcgc
    31261 cggaagcaaa gaaatctgtg aaattctggg acggaaattt agtaaagctg attttgttta
    31321 atccggttta tgcaggactg acggtaagag ggaaaacaga aaccagggtt ccgtcaaaaa
    31381 gagagtaccg atatatttca agagaggatt ggatttgcgt aaaaggagga cacgaagcga
    31441 ttgtaacgga acaggagctt caggagatcc aggacatggt acagaaggac agaaaatatc
    31501 atgggtctac accgtcttct gagaatattt ttgcaggctt gatccgttgc gggcattgtg
    31561 gtcggaaaat gcggatacgg acagaataca aagaaaagcc gatttattgt aaaagtgtta
    31621 cgacagcccc caatgcttcc tgttatccaa agaaatataa gcagaaagag ttggaagaac
    31681 tggtgctaat tatgataaga cagcaggtag cccttgcaga ggataccata aagcagttaa
    31741 agaaagccaa tcagactttg aatattccga aactccgata tcgaaaaaag caatatgaaa
    31801 agaagttggc actttgtaaa caggagaaaa tggaactgta tgaacaatat gcagaagaac
    31861 agatttccct gaaggactac ctggcacgaa aacaaacttg tatggagaaa atagcagctt
    31921 atcagcaaaa gatacaggag atagaagcaa gaattttaaa aggggaggag gaaaaacaaa
    31981 aggagaaatc agaaggatta caactttttg taaaatatca gggatta
//
