GCA_009881405.1 - 7 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaPJNPCCEG_35 (original name was: gnl|Prokka|PJNPCCEG_35)

Region	Type	From	To	Most similar known cluster		Similarity
Region 35.1	cyclic-lactone-autoinducer	1	6,435

gnlProkkaPJNPCCEG_46 (original name was: gnl|Prokka|PJNPCCEG_46)

Region	Type	From	To	Most similar known cluster		Similarity
Region 46.1	lanthipeptide-class-ii	1	5,457

gnlProkkaPJNPCCEG_99 (original name was: gnl|Prokka|PJNPCCEG_99)

Region	Type	From	To	Most similar known cluster		Similarity
Region 99.1	NRPS	1	38,562	dipeptide aldehydes	NRP	47%

gnlProkkaPJNPCCEG_131 (original name was: gnl|Prokka|PJNPCCEG_131)

Region	Type	From	To	Most similar known cluster		Similarity
Region 131.1	ranthipeptide	6,605	29,220

gnlProkkaPJNPCCEG_163 (original name was: gnl|Prokka|PJNPCCEG_163)

Region	Type	From	To	Most similar known cluster		Similarity
Region 163.1	ranthipeptide	59,463	81,051

gnlProkkaPJNPCCEG_196 (original name was: gnl|Prokka|PJNPCCEG_196)

Region	Type	From	To	Most similar known cluster		Similarity
Region 196.1	lanthipeptide-class-ii	1	21,771

gnlProkkaPJNPCCEG_203 (original name was: gnl|Prokka|PJNPCCEG_203)

Region	Type	From	To	Most similar known cluster		Similarity
Region 203.1	cyclic-lactone-autoinducer	1	12,098	ruminococcin A	RiPP:Lanthipeptide	21%

Region	Type	From	To	Most similar known cluster	Similarity
Region 35.1	cyclic-lactone-autoinducer	1	6,435
Region 46.1	lanthipeptide-class-ii	1	5,457
Region 99.1	NRPS	1	38,562	dipeptide aldehydes	NRP	47%
Region 131.1	ranthipeptide	6,605	29,220
Region 163.1	ranthipeptide	59,463	81,051
Region 196.1	lanthipeptide-class-ii	1	21,771
Region 203.1	cyclic-lactone-autoinducer	1	12,098	ruminococcin A	RiPP:Lanthipeptide	21%

Compact view

gnlProkkaPJNPCCEG_35 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 6,435 nt. (total: 6,435 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaPJNPCCEG_46 - Region 1 - lanthipeptide-class-ii

Download region GenBank file

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Location: 1 - 5,457 nt. (total: 5,457 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptide(s) for ctg46_1

ctg46_2

Leader:

MKGEIIMSEMRNPITREENFS

Core:

NPAGNVMMELQEADLNKFVAGAGETRNSGGVLCTSTAECYFGTLLKPCCPKK

Core with dehydrations:

NPAGNVMMELQEADLNKFVAGAGEDhbRNDhaGGVLCysDhbDhaDhbAECysYFGDhbLLKPCysCysPKK

MIBiG 3.1 matches for ctg46_2

15.4% BGC0002110 (QKV49893.1): Lanthipeptide: birimositide

27

NSGGVLCTSTAEC

39

N+GG CT T EC

14

NNGG-WCTLTKEC

25

11.5% BGC0000517 (BAB04173.1): Lanthipeptide: haloduracin β or haloduracin α

30

GVLCTSTAEC

39

G CT T EC

14

GAYCTLTVEC

23

7.7% BGC0001229 (SBI_06990): Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

33

CTSTAEC

39

CT + EC

28

CTLSKEC

34

antiSMASH-DB 4.0 matches for ctg46_2

100.0% NZ_CZAY01000009.1and 12 others:

NZ_CZBA01000009.1 Lanthipeptides: ARA06_RS08755_lanthipeptideNZ_CZBB01000003.1 Lanthipeptides: ARA29_RS04330_lanthipeptideNZ_JADPDU010000003.1 Lanthipeptides: I4V06_RS02990_lanthipeptideNZ_JAOQJU010000001.1 Lanthipeptides: OCV99_RS00835_lanthipeptideNZ_JAQCSY010000025.1 Lanthipeptides: PGZ10_RS13865_lanthipeptideNZ_JAQEDC010000020.1 Lanthipeptides: PHA23_RS12680_lanthipeptideNZ_QRZZ01000001.1 Lanthipeptides: DWV87_RS01465_lanthipeptideNZ_QSUB01000001.1 Lanthipeptides: DXB81_RS03120_lanthipeptideNZ_QUCI01000019.1 Lanthipeptides: DW648_RS14740_lanthipeptideNZ_QULD01000003.1 Lanthipeptides: DXB83_RS07060_lanthipeptideNZ_QULI01000007.1 Lanthipeptides: DXB71_RS08970_lanthipeptideNZ_SLZV01000043.1 Lanthipeptides: EDD74_RS14380_lanthipeptide

Lanthipeptides: ARA07_RS06830_lanthipeptide

1

NPAGNVMMELQEADLNKFVAGAGETRNSGGVLCTSTAECYFGTLLKPCCPKK

52

NPAGNVMMELQEADLNKFVAGAGETRNSGGVLCTSTAECYFGTLLKPCCPKK

1

NPAGNVMMELQEADLNKFVAGAGETRNSGGVLCTSTAECYFGTLLKPCCPKK

52

36.5% NZ_QRHZ01000008.1and 2 others:

NZ_QSRF01000021.1 Lanthipeptides: DXC87_RS15310_lanthipeptideNZ_QUEQ01000033.1 Lanthipeptides: DXA48_RS19000_lanthipeptide

Lanthipeptides: DW272_RS13830_lanthipeptide

22

AGETRNSGGVLCTSTAECYFGTLLKPCC

49

AGE RNSGG+ CTST EC GTL CC

1

AGEPRNSGGMFCTSTGECNMGTLNIFCC

28

32.7% NZ_CYXV01000003.1: Lanthipeptides: ARB75_RS04585_lanthipeptide

22

AGETRNSGGVLCTSTAECYFGTLLKPCC

49

AG RNSGG+ CT T EC GT +K CC

1

AGVARNSGGIACTLTGECNIGTHIKFCC

28

with 44 more sequence matches

25.0% NZ_CP071875.1: Lanthipeptides: J4I02_RS02880_lanthipeptide

23

GETRNSGGVLCTSTAECYFGTLLKPCC

49

G +SGG +CT T EC GT CC

2

GIPNHSGGAICTLTHEC-AGTHWYSCC

27

21.2% NC_009480.1and 10 others:

NZ_CP033724.1 Lanthipeptides: EFE39_RS10220_lanthipeptideNZ_CP047051.1 Lanthipeptides: GRD74_RS10365_lanthipeptideNZ_CP047054.1 Lanthipeptides: GRD61_RS10460_lanthipeptideNZ_CP053860.1 Lanthipeptides: DQP62_RS10825_lanthipeptideNZ_CP076352.1 Lanthipeptides: KN218_RS09900_lanthipeptideNZ_CP085137.1 Lanthipeptides: LHJ48_RS10290_lanthipeptideNZ_CP085140.1 Lanthipeptides: LHJ47_RS10305_lanthipeptideNZ_CP095274.1 Lanthipeptides: MU580_RS10460_lanthipeptideNZ_PSTW01000024.1 Lanthipeptides: C5C03_RS09675_lanthipeptideNZ_SISU01000002.1 Lanthipeptides: EOG37_RS09890_lanthipeptide

Lanthipeptides: CMM_RS10575_lanthipeptide

27

NSGGVLCTSTAECYFGTLLKPC

48

+S G LCT T EC GT++ C

1

SSSGWLCTLTIEC--GTIICAC

20

21.2% NZ_CP036455.1and 1 other:

NZ_JAODUN010000003.1 Lanthipeptides: BXY51_RS10560_lanthipeptide

Lanthipeptides: EKD16_RS25235_lanthipeptide

28

SGGVLCTSTAECYFGTLLKPC

48

S G +CT T EC GTL+ C

1

SSGWVCTLTIEC--GTLVCAC

19

21.2% NZ_CP045267.1and 1 other:

NZ_CP045267.1 Lanthipeptides: FDZ14_RS00155_lanthipeptide

Lanthipeptides: FDZ14_RS00155_lanthipeptide

30

GVLCTSTAECYFGTLLKPCCPKK

52

GV+ T+T+ECY GT CC +

3

GVVKTATSECYLGTFAFACCLAR

25

21.2% NZ_CP061274.1and 1 other:

NZ_JADKRR010000001.1 Lanthipeptides: ITJ40_RS10085_lanthipeptide

Lanthipeptides: H9X71_RS09850_lanthipeptide

28

SGGVLCTSTAECYFGTLLKPC

48

S G LCT T EC GT + C

2

SSGWLCTLTIEC--GTFICAC

20

21.2% NZ_CP117876.1: Lanthipeptides: PQ460_RS01735_lanthipeptide

30

GVLCTSTAECYFGTLLKPCCPKK

52

GV+ T+T+ECY GT+ CC +

3

GVVKTATSECYLGTVAFICCLGR

25

21.2% NZ_FQZK01000006.1and 2 others:

NZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13060_lanthipeptideNZ_FQZK01000006.1 Lanthipeptides: BUE45_RS13060_lanthipeptide

Lanthipeptides: BUE45_RS13060_lanthipeptide

16

NKFVAGAGETRNSGGVLCTSTAEC

39

N +A A +RN+ G CT T EC

11

NPLIACALLSRNNTGRFCTVTVEC

34

21.2% NZ_JAFCGV010000005.1: Lanthipeptides: JQI09_RS04275_lanthipeptide

30

GVLCTSTAECYFGTLLKPCCPKK

52

GV+ T+T+ECY GT CC +

3

GVVKTATSECYLGTFAFVCCLAR

25

21.2% NZ_NTSR01000029.1and 1 other:

NZ_NTSR01000029.1 Lanthipeptides: CN358_RS25180_lanthipeptide

Lanthipeptides: CN358_RS25180_lanthipeptide

9

ELQEADLNKFVAGAGETRNSGGVLCTSTAEC

39

AD K G G G +CT T EC

10

SFNSADYIKLSIGLGNN----GYICTYTVEC

36

19.2% NZ_AUBN01000022.1: Lanthipeptides: G448_RS16025_lanthipeptide

28

SGGVLCTSTAECYFGTLLKPC

48

S G CT T EC GT + C

2

SSGWFCTLTIEC--GTFICAC

20

19.2% NZ_CAKMMP010000011.1: Lanthipeptides: L6H98_RS19925_lanthipeptide

21

GAGETRNSGGVLCTSTAECYFGTL

44

A E SGGV CT + EC++ ++

2

AAIEAAKSGGVFCTVSHECHYNSV

25

19.2% NZ_CP016767.1: Lanthipeptides: BCV50_RS18735_lanthipeptide

27

NSGGVLCTSTAECYFGTL

44

N+ G CT +AEC FGT+

17

NNYGQYCTVSAEC-FGTI

33

19.2% NZ_CP028130.1: Lanthipeptides: C7V51_RS14690_lanthipeptide

28

SGGVLCTSTAECYFGTLLKPC

48

S G +CT T EC GT++ C

2

SSGWMCTLTIEC--GTIICAC

20

19.2% NZ_CP083176.1and 4 others:

NZ_JABUHD010000002.1 Lanthipeptides: HRR08_RS05415_lanthipeptideNZ_LSLF01000001.1 Lanthipeptides: AXE72_RS04025_lanthipeptideNZ_PNHB01000001.1 Lanthipeptides: CJ210_RS02800_lanthipeptideNZ_QJVA01000001.1 Lanthipeptides: D0T19_RS02755_lanthipeptide

Lanthipeptides: K9E37_RS06280_lanthipeptide

30

GVLCTSTAECYFGT--LLKPCC

49

GV+ T T EC+ T L CC

3

GVMHTLTHECHMNTWQFLLTCC

24

19.2% NZ_CP102267.1and 11 others:

NZ_FMUW01000051.1 Lanthipeptides: BLP57_RS16830_lanthipeptideNZ_JAQDBP010000004.1 Lanthipeptides: PGY07_RS07130_lanthipeptideNZ_JAQEHQ010000024.1 Lanthipeptides: PGR68_RS13915_lanthipeptideNZ_JAQESL010000043.1 Lanthipeptides: PG840_RS15980_lanthipeptideNZ_JAQESS010000001.1 Lanthipeptides: PG808_RS00050_lanthipeptideNZ_LN913006.1 Lanthipeptides: BN3261_RS01470_lanthipeptideNZ_QRPQ01000011.1 Lanthipeptides: DWZ74_RS14610_lanthipeptideNZ_QRZZ01000003.1 Lanthipeptides: DWV87_RS03120_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: DW767_RS16305_lanthipeptideNZ_QSKF01000004.1 Lanthipeptides: DW740_RS06255_lanthipeptideNZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03580_lanthipeptide

Lanthipeptides: NQ550_RS04155_lanthipeptide

32

LCTSTAECYFGTLLKPCC

49

CTST EC +GT++ CC

2

FCTSTKECNWGTIMFVCC

19

19.2% NZ_FMVM01000006.1and 2 others:

NZ_RIAS01000010.1 Lanthipeptides: EC604_RS18225_lanthipeptideNZ_VEJI01000010.1 Lanthipeptides: FS576_RS22075_lanthipeptide

Lanthipeptides: BLQ13_RS10365_lanthipeptide

21

GAGETRNSGGVLCTSTAECYFGTL

44

A E + SGGV CT + EC++ ++

2

AAIEDKKSGGVFCTVSHECHYNSV

25

19.2% NZ_GG666304.1: Lanthipeptides: HMPREF0077_RS09155_lanthipeptide

26

RNSGGVLCTSTAECYFGTLL

45

++S G CT T EC F TL+

13

KDSCGHGCTITTECPFATLI

32

19.2% NZ_JAESIP010000017.1and 3 others:

NZ_LT907978.1 Lanthipeptides: EHLA_RS12685_lanthipeptideNZ_QRYY01000029.1 Lanthipeptides: DWW21_RS18370_lanthipeptideNZ_SPFW01000044.1 Lanthipeptides: FGQ81_RS16590_lanthipeptide

Lanthipeptides: JMK14_RS12260_lanthipeptide

28

SGGVLCTSTAECYFGTLL

45

S G LCT TAEC T++

15

SCGRLCTGTAECPIMTII

32

19.2% NZ_JALAMD010000003.1and 1 other:

NZ_JALAMZ010000007.1 Lanthipeptides: MOC43_RS14030_lanthipeptide

Lanthipeptides: MOB22_RS05100_lanthipeptide

27

NSGGVLCTSTAECYFGTL

44

N+ G CT +AEC FGT+

17

NNYGKYCTVSAEC-FGTI

33

17.3% NZ_ALVU02000002.1and 1 other:

NZ_ALVU02000002.1 Lanthipeptides: SYN7509_RS28800_lanthipeptide

Lanthipeptides: SYN7509_RS28800_lanthipeptide

16

NKFVAGAGETRNSGGVLCT

34

KF G E+ NSG + CT

1

RKFTYGGDESCNSGIIACT

19

17.3% NZ_BMRY01000003.1and 28 others:

NZ_BMRY01000003.1 Lanthipeptides: IE140_RS12370_lanthipeptideNZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12780_lanthipeptideNZ_BMSZ01000006.1 Lanthipeptides: IE135_RS12780_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05285_lanthipeptideNZ_BNBJ01000003.1 Lanthipeptides: IE304_RS05285_lanthipeptideNZ_CP021707.1 Lanthipeptides: CCZ36_RS18205_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19425_lanthipeptideNZ_CP079114.1 Lanthipeptides: KV381_RS19425_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34965_lanthipeptideNZ_CP084357.1 Lanthipeptides: LEL86_RS34965_lanthipeptideNZ_CP116355.1 Lanthipeptides: KPP03845_RS17815_lanthipeptideNZ_CP116355.1 Lanthipeptides: KPP03845_RS17815_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11020_lanthipeptideNZ_JALDPQ010000054.1 Lanthipeptides: MQC87_RS11020_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32880_lanthipeptideNZ_JAMFLF010000021.1 Lanthipeptides: M1212_RS32880_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS38630_lanthipeptideNZ_JNLT01000014.1 Lanthipeptides: CD02_RS38630_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100145_lanthipeptideNZ_JNZV01000231.1 Lanthipeptides: BG84_RS0100145_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18455_lanthipeptideNZ_KZ819178.1 Lanthipeptides: DBP20_RS18455_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19720_lanthipeptideNZ_LZRD01000017.1 Lanthipeptides: A3Q37_RS19720_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03735_lanthipeptideNZ_NNBN01000001.1 Lanthipeptides: CG717_RS03735_lanthipeptideNZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29300_lanthipeptideNZ_WHOM01000078.1 Lanthipeptides: GCN81_RS29300_lanthipeptide

Lanthipeptides: IE140_RS12370_lanthipeptide

21

GAGETRNSGGVLCTSTAEC

39

GA + G CT+TAEC

15

GASYVLGNNGNFCTATAEC

33

17.3% NZ_CP034669.1: Lanthipeptides: EJ065_RS32040_lanthipeptide

26

RNSGGVLCTSTAEC

39

RNS G +CT T EC

7

RNSCGYVCTLTTEC

20

17.3% NZ_CP040409.1and 4 others:

NZ_CP040411.1 Lanthipeptides: FE334_RS06825_lanthipeptideNZ_CP040422.1 Lanthipeptides: FE323_RS09430_lanthipeptideNZ_JH601103.1 Lanthipeptides: HMPREF9703_RS02710_lanthipeptideNZ_NAQX01000046.1 Lanthipeptides: B8A46_RS06295_lanthipeptide

Lanthipeptides: FE336_RS08590_lanthipeptide

26

RNSGGVLCTSTAEC

39

R+S G CT TAEC

12

RHSCGRACTITAEC

25

17.3% NZ_CP086242.1and 1 other:

NZ_CP086245.1 Lanthipeptides: LL037_RS25615_lanthipeptide

Lanthipeptides: LL038_RS25355_lanthipeptide

28

SGGVLCTSTAEC-YFGTL

44

S G +CT+T EC YF +

2

SSGAICTATTECTYFSAI

19

17.3% NZ_CP092836.1: Lanthipeptides: MLD62_RS30280_lanthipeptide

14

DLNKFVAGAGETRNSGGVLCTSTAEC

39

+L+ +A A + + G CT +AEC

2

NLSAAIADAAGLKGNYGKFCTYSAEC

27

17.3% NZ_JAENHX010000011.1: Lanthipeptides: JIN86_RS20375_lanthipeptide

15

LNKFVAGAGETRNSGGVLCTSTAEC

39

+++ +A A N+ G+ CT +AEC

7

ISRAIANAVGLGNNYGMACTWSAEC

31

17.3% NZ_QORY01000016.1and 1 other:

NZ_QORY01000016.1 Lanthipeptides: DT250_RS18255_lanthipeptide

Lanthipeptides: DT250_RS18255_lanthipeptide

30

GVLCTSTAECYFGTLLKP

47

G +CT T EC G L P

23

GRICTYTLECTAGCNLNP

40

16.4% NZ_AP023359.1: Lanthipeptides: Prubr_RS34925_lanthipeptide

1

NPAGNVMM--ELQEADLNKFVAGAGET

25

NPAG + + + EAD+ +G G T

13

NPAGPLFLGGKYAEADITATGSGGGAT

39

15.4% NZ_CP018620.1and 1 other:

NZ_CP062165.1 Lanthipeptides: JNUCC31_RS16755_lanthipeptide

Lanthipeptides: BS614_RS05680_lanthipeptide

24

ETRNSGGVLCTSTAECYFGTL

44

+ + SGGV CT + EC++ ++

5

DAQASGGVFCTVSHECHYNSV

25

15.4% NZ_CP022163.1: Lanthipeptides: MEBOL_RS24465_lanthipeptide

27

NSGGVLCTSTAEC

39

NSGG +CT + EC

10

NSGGWICTYSTEC

22

15.4% NZ_CP030280.1and 5 others:

NZ_CP030280.1 Lanthipeptides: DQQ01_RS07655_lanthipeptideNZ_CP030280.1 Lanthipeptides: DQQ01_RS07650_lanthipeptideNZ_CP030280.1 Lanthipeptides: DQQ01_RS07645_lanthipeptideNZ_CP030280.1 Lanthipeptides: DQQ01_RS07650_lanthipeptideNZ_CP030280.1 Lanthipeptides: DQQ01_RS07645_lanthipeptide

Lanthipeptides: DQQ01_RS07655_lanthipeptide

23

GETRNSG--GVLCTSTAEC

39

G++++ G G LC+ T EC

1

GKSKDWGNDGYLCSVTVEC

19

15.4% NZ_CP034248.1: Lanthipeptides: EIM92_RS14995_lanthipeptide

28

SGGVLCTSTAECYFGTL

44

SGGV+CT + EC++ ++

6

SGGVICTISHECHYNSV

22

15.4% NZ_CP086142.1and 3 others:

NZ_CP086142.1 Lanthipeptides: LL065_RS25460_lanthipeptideNZ_CP086142.1 Lanthipeptides: LL065_RS25455_lanthipeptideNZ_CP086142.1 Lanthipeptides: LL065_RS25450_lanthipeptide

Lanthipeptides: LL065_RS25465_lanthipeptide

29

GGVLCTSTAECYFGTL

44

GGV+ T T ECY+ ++

2

GGVITTFTHECYYNSV

17

15.4% NZ_CP091285.1: Lanthipeptides: L2Z92_RS16370_lanthipeptide

23

GETRNSGGVLCTSTAEC

39

G+TR + G C +TA C

1

GKTRTASGSTCDNTAVC

17

15.4% NZ_CP114875.1: Lanthipeptides: O4Z47_RS14375_lanthipeptide

26

RNSGGVLCTSTAEC

39

+NS G +CT T+EC

5

KNSSGDICTLTSEC

18

15.4% NZ_CP115450.1and 1 other:

NZ_CP115450.1 Lanthipeptides: O1G21_RS35415_lanthipeptide

Lanthipeptides: O1G21_RS35415_lanthipeptide

30

GVLCTSTAEC

39

G LCT TAEC

22

GYLCTVTAEC

31

15.4% NZ_JADPCZ010000011.1and 1 other:

NZ_OW659477.1 Lanthipeptides: NMG62_RS06660_lanthipeptide

Lanthipeptides: I4W03_RS06785_lanthipeptide

26

RNSGGVLCTSTAECYFGTLL

45

++S G CT T EC T++

13

KHSCGRACTVTTECPIATII

32

15.4% NZ_JALMDK010000017.1: Lanthipeptides: allorf_059288_059443_lanthipeptide

28

SGGVLCTSTAEC

39

SGG +CT T EC

2

SGGYICTLTWEC

13

13.5% NZ_BCEY01000006.1and 1 other:

NZ_BCEY01000006.1 Lanthipeptides: GOZ53_RS01290_lanthipeptide

Lanthipeptides: GOZ53_RS01290_lanthipeptide

30

GVLCTSTAEC

39

G +CT TAEC

23

GWICTWTAEC

32

13.5% NZ_CP077726.1and 12 others:

NZ_CP077726.1 Lanthipeptides: KTC92_RS18420_lanthipeptideNZ_CP077726.1 Lanthipeptides: KTC92_RS18415_lanthipeptideNZ_CP077726.1 Lanthipeptides: KTC92_RS18410_lanthipeptideNZ_CP077726.1 Lanthipeptides: KTC92_RS18405_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19070_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19065_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19060_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19055_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19050_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19045_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19040_lanthipeptideNZ_CP086248.1 Lanthipeptides: LL036_RS19035_lanthipeptide

Lanthipeptides: KTC92_RS18425_lanthipeptide

30

GVLCTSTAECYFGTL

44

GV+ T T ECY+ ++

3

GVITTFTHECYYNSV

17

13.5% NZ_JAQDBP010000004.1and 18 others:

NZ_JAQDBP010000004.1 Lanthipeptides: PGY07_RS07085_lanthipeptideNZ_JAQEAL010000002.1 Lanthipeptides: PGU65_RS02165_lanthipeptideNZ_JAQESL010000010.1 Lanthipeptides: PG840_RS09145_lanthipeptideNZ_JAQEUC010000007.1 Lanthipeptides: PG788_RS06860_lanthipeptideNZ_QRHW01000005.1 Lanthipeptides: DW641_RS05035_lanthipeptideNZ_QROS01000011.1 Lanthipeptides: DW021_RS13630_lanthipeptideNZ_QRPQ01000001.1 Lanthipeptides: DWZ74_RS02490_lanthipeptideNZ_QRZZ01000003.1 Lanthipeptides: DWV87_RS03165_lanthipeptideNZ_QRZZ01000003.1 Lanthipeptides: DWV87_RS03165_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: DW767_RS16350_lanthipeptideNZ_QSJW01000012.1 Lanthipeptides: DW767_RS16350_lanthipeptideNZ_QSKF01000004.1 Lanthipeptides: DW740_RS06305_lanthipeptideNZ_QSKF01000004.1 Lanthipeptides: DW740_RS06305_lanthipeptideNZ_QTZB01000014.1 Lanthipeptides: DXC15_RS13895_lanthipeptideNZ_QUCI01000011.1 Lanthipeptides: DW648_RS10830_lanthipeptideNZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03630_lanthipeptideNZ_QUJJ01000004.1 Lanthipeptides: DW748_RS03630_lanthipeptideNZ_QUKU01000006.1 Lanthipeptides: DXC27_RS05470_lanthipeptide

Lanthipeptides: PGY07_RS07085_lanthipeptide

24

ETRNSGGVLCTSTAEC

39

++ S GV+CT + EC

8

DSLASSGVVCTISVEC

23

13.5% NZ_NTSR01000034.1: Lanthipeptides: CN358_RS26370_lanthipeptide

30

GVLCTSTAECYF

41

G +CT +AEC F

20

GTMCTVSAECMF

31

11.5% NZ_VDYW01000008.1: Lanthipeptides: allorf_137107_137307_lanthipeptide

40

YFGTLLKPCCP

50

Y G +L CCP

10

YVGDILLNCCP

20

9.6% NZ_AP018194.1: Lanthipeptides: CA739_RS01285_lanthipeptide

39

CYFGTLLKPC

48

C+ T++KPC

2

CFVSTIIKPC

11

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg46_2 - Class II

Cleavage pHMM score: -7.00

RODEO score: 0

Monoisotopic mass: 5354.6 Da

Molecular weight: 5358.1 Da

Number of bridges: 4

Alternative weights: (assuming N unmodified Ser/Thr residues); 5376.2 Da N = 1; 5394.2 Da N = 2

gnlProkkaPJNPCCEG_99 - Region 1 - NRPS

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Location: 1 - 38,562 nt. (total: 38,562 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 38562:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - X - X)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg99_9

AMP-binding (20..419): X

nrpys: Leu, Trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVLTDGGISK
Nearest Stachelhaus code(s):: Leu or Trp DVLTDGGISK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1033..1421): X

nrpys: Leu, Trp

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAMFSGAIFK
Nearest Stachelhaus code(s):: Leu or Trp DAMFSGAIFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (2027..2418): X

nrpys: Leu, Trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DAITTGGVSK
Nearest Stachelhaus code(s):: Leu or Trp DAITTGGVSK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaPJNPCCEG_131 - Region 1 - ranthipeptide

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Location: 6,605 - 29,220 nt. (total: 22,616 nt) Show pHMM detection rules used

Region on contig edge.

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

Legend:

core biosynthetic genes

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KnownClusterBlast

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Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaPJNPCCEG_163 - Region 1 - ranthipeptide

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Location: 59,463 - 81,051 nt. (total: 21,589 nt) Show pHMM detection rules used

ranthipeptide: (TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085 or SPASM)) and minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716 or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or (YcaO or TIGR03604))))

Legend:

core biosynthetic genes

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Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaPJNPCCEG_196 - Region 1 - lanthipeptide-class-ii

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Location: 1 - 21,771 nt. (total: 21,771 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

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Lanthipeptides

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		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptide(s) for ctg196_10

allorf_00598_00783

Leader:

MSLNFSTYAYITKSPVRYSDAAVFSA

Core:

AAPDYHHPELFPVLLLFHTRELYPHMTEVTCFQTL

Core with dehydrations:

AAPDYHHPELFPVLLLFHDhbRELYPHMDhbEVDhbCysFQDhbL

antiSMASH-DB 4.0 matches for allorf_00598_00783

14.3% NZ_CP058552.1: Lanthipeptides: allorf_1481579_1481740_lanthipeptide

23

YPHMTEVTCFQTL

35

Y H+ + C QT+

6

YKHVQKTNCVQTI

18

allorf_15654_15782

Leader:

MLQLLTILLTPIYFRMHLQAG

Core:

QILTCLVVLMVIFIVTHYTCN

Core with dehydrations:

QILDhbCysLVVLMVIFIVDhbHYDhbCysN

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

allorf_00598_00783 - Class II

Cleavage pHMM score: -6.80

RODEO score: 0

Monoisotopic mass: 4093.1 Da

Molecular weight: 4095.7 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 4113.7 Da N = 1; 4131.7 Da N = 2; 4149.7 Da N = 3

allorf_15654_15782 - Class II

Cleavage pHMM score: -4.90

RODEO score: 0

Monoisotopic mass: 2368.3 Da

Molecular weight: 2369.9 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 2388.0 Da N = 1

gnlProkkaPJNPCCEG_203 - Region 1 - cyclic-lactone-autoinducer

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Location: 1 - 12,098 nt. (total: 12,098 nt) Show pHMM detection rules used

Region on contig edge.

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1