LOCUS       c00044_gnlPro..        23974 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PJNPCCEG_44.
ACCESSION   c00044_gnlPro..
VERSION     c00044_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 00:45:02
            Original ID  :: gnl|Prokka|PJNPCCEG_44
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 41809
            Orig. end    :: 65783
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23974
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[51809:57132]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..15323
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..23974
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23974
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             1456..2340
                     /locus_tag="ctg44_37"
                     /transl_table=11
                     /translation="MEQRIKGTTGLMALIGSPVGHSGSPAMYNFSFRHHNLDYAYMAFD
                     IKEDQVPAALDAIRLFKMRGANVTMPCKNEVAKHMDELSPAARIIGAVNTIVNEDGKLV
                     GHITDGIGFVRNLKEHGVDVKGKKMVVLGAGGAATAIQVQCALDGAESISIFNPKDPFF
                     ARAESTAEKLSKETPDCKVSVFDLADEAKLKEEVANADILVNATLAGMKPHEELTLIKD
                     KSMFRPDLVVADVVYNPAETRMVKEAKEAGCKLAIGGKGMLLWQGAAAYKLYTGLEMPT
                     AEYQKFQEENENK"
     CDS             2361..3560
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MFS_1"
                     /gene_functions="transport (smcogs) SMCOG1058:Major
                     facilitator family (Score: 53.8; E-value: 5e-17)"
                     /gene_kind="transport"
                     /locus_tag="ctg44_38"
                     /sec_met_domain="MFS_1 (E-value: 4.6e-17, bitscore: 53.8,
                     seeds: 192, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQKTNKMLIFTSLAAYFTYFIHGIGASILGQYKPEFAAAWGAKP
                     LADGTLDVSMVVSVIAALGLGRLISLPFSGPLSDKYGRKLSGIIGVLCYVAYFFGMANS
                     TSMAMGYAFAVIGGIANSFLDTCVSPTCMEIYVNNPSVANLFTKFSICLSQFLLPFLIG
                     IVASANMSYKTIFIVAGIAILIDGILILILPFPAREKKVQDKADKKKSGHKISPAAIAA
                     ILIGFTSSSTFMLWLNCNQELARSYGMADPSKIQSLYALGTATAILATAAFIKKGLKEI
                     NVLILYPLISTIMLLLCYFIQAPFICLIGGFVIGYAGAGGVLQLAVSTTAEFFPENKGT
                     ATSLVMIASSIANYTILSLAGYITKVGGSSAPRMILLLNMAVTIIGILLALFVKKNRNQ
                     "
     CDS             3853..5211
                     /locus_tag="ctg44_39"
                     /transl_table=11
                     /translation="MANTRTQRRENELPYIPFGPFQIRLPFIHYKIESVEFIQGLILGV
                     TALAAVPYLEQYLGLPYELAWSCVIIETFLYLLHSLLGDPVVPGWITPTLPLTIVFLEG
                     FPMGKERIQAMIALQMLVGLVFIFMGVTRLADKFVHAVPNSVKGGILLAAPVTVMAGQL
                     GENGNMHKYPLAIVAGVGLLILISFSDKYQEKRKTNKFLDLVARYGNLFPYLIAMVVGL
                     LVGELDAPGLEIGTFIKIPQFKDIIDQVSIFGVGIPPASMFIKALPLALVCYVIAFGDF
                     VTTETLVSEARQARDDEYIDFNSSRSNLVSGLRNLILSIIAPFPPLSGPLWVGMTVSVS
                     MRYKEGKKAMKSLLGGMASFRLATFLSVLIIPVVSFFRPIFGVGSSITLMFQAFVCARI
                     GMDYCKSDRDKMIAGVMAAVLATQGTAWASAWALAVGFGLNIFLSNWNPLEKK"
     CDS             complement(5392..6153)
                     /locus_tag="ctg44_40"
                     /transl_table=11
                     /translation="MNTVQVKNTVIGEGRPKICVPIVGKTKTDILEEAKKITTLPVDVV
                     EWRVDWFDDVFATEKVLETAKELQEVLKDIPVLLTFRTSKEGGEKEISVNDYAALNIAA
                     AQSGYVDLIDVEAFTGDEVVKTIINAAHEAGVKVIASNHDFFKTPEKEEIIRRLRMMQD
                     FGADIPKMAVMPTCKQDVLTLLSATLEMSEKYADRPIITMSMAGTGVVSRLTGETFGSA
                     LTFGAASKASAPGQVGVHELKQVLDIIHSSL"
     CDS             complement(6422..7300)
                     /locus_tag="ctg44_41"
                     /transl_table=11
                     /translation="MAERITGHTELIGLMAYPIRHSSSPAMQNEAFAKLGYDYAYLAFE
                     VGADEIEDAVKAIRTLKMRGSNVSMPNKTLVGKYLDELSPAAELCGAVNTIVNDNGHLT
                     GHITDGIGFMSALKDNDIDVIGKKMTIVGAGGAATAIEIQAALDGVAEITIFNRRDEFW
                     DRAVSTVEKINTKTSCHAVLYDLADLDKLKAEMDNSFIFVNATGVGMKPLEGQSVVPDK
                     SYFRPELIVIDVPYSPLETKMRSMAKEVGCKTMNGLGMMLFQGSAAFELWTGEPMPIEH
                     MKEILHISYDD"
     CDS             complement(7337..9337)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) baiH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_42"
                     /sec_met_domain="baiH (E-value: 1.7e-144, bitscore: 474.4,
                     seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSNYQHIFTPLTVKNMTIKNRIVMMPMGTNYGEQNGEMSFLHIN
                     YYKERAKGGTGLIIVENASVDSPQGSNGTTQLRIDHDNYLPRLYKFCEEIHKYGTCIAI
                     QINHAGASAVSARTNMQPVSASDIPSKEGGEIPRPLSVEEIHHIVKKYGEAAKRAQAAG
                     FDAVEVHAGHSYLISQFLSPLTNKRTDEFGGSVENRTRFCRMVIEEVRKQVGPFFPIML
                     RLSADELMEGGNTLEDTLEYLEYVQDEVDIFDVSCGLNGSIQYQIDANYMKDGWRSYMP
                     KAVREKFGKPCISMGNIRNPKVAEQILADGDADLIGMGRGLIAEPAWVNKVATGRECDL
                     RKCISCNIGCAGNRIGFNRPIRCTVNPAVLEGDVYKNQKVNKNCNVVVIGGGTAGLEAA
                     CTAAEVGCNTFLLEKGETLGGLASVISKIPAKKRLADFPNYLIQRAEQLENLYIFTNTE
                     GTPENIRKFHPNLIVSSTGSAPLLPPIRGLHDRIDKEGSKVASILGMINHINDYPEDMT
                     GKKVVVVGGGAVGLDVVEFFAARNAEISIVEMMDQIGRDLDPVTKNDMKDQMKKHHVTQ
                     LTKTALQEVKDSSFLVRDAEGERELPFDYGFVCLGMRAQGQLFAELSDAFVSDDVEILN
                     IGDSKRARKIIDGTLEGRNILNTLTQMGYLQ"
     CDS             10001..11437
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_43"
                     /sec_met_domain="CT_Vparvula (E-value: 7e-136, bitscore:
                     445.5, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNATQSLAGTRITSLLDANSFVEIGQGVTARSTDFNMTANKAPS
                     DGVITGYGVIDDKLVYVYSQDASVLNGTVGEMHAKKITRLYDLAMKTGAPVIGLVDCAG
                     IRLQEATDALEAFGQIYLKQTLASGVIPQITAIFGTCGGGMAVIPSLTDFTFMESKKGK
                     MFVNTPNALEGNNTDKCDTAAADFQSKETGVIDGVGTEDEILGQIRSLVSLLPSNNEDT
                     DNYTECTDDLNRVCADLANCAGDTAIALSQIADNGEFFETKADYAKDMVTGFIRLNGAT
                     VGAVANRSEVYDAEGKKVETFDGSISARGARKAADFVKFCDAFDIPVLTLTNATGFMAT
                     LCSEKMMAKSVGELVAAFADATVPKVNVIIGKAYGTAYVAMNSKSIGADLVYAWDNAEI
                     GMMDASLAAKIMYADADAAELNEKAAQYRELQNGVASAAARGYVDTVISPADTRKYVIG
                     AFEMLFTKREDRPSKKHGTV"
     CDS             11485..12207
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_44"
                     /sec_met_domain="OAD_gamma (E-value: 3.6e-27, bitscore:
                     86.8, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFLVMAALVIGSTSVVFAADKVDDTVKSTLVTTAEGLTDAIVQL
                     KDEEIENYMSSGDDFTTSAMQSWQTSKDELGAKKDSNGETTVTFKDDQYTVTVPLKFEK
                     AEANFVYVFDSQGTPTSMSVDVQYGMGKTLQRAGLNTLMGIGTVFVMLILLSLLISLFR
                     FIPNPEAKKAAEAKAAKAAKEAEAAAIAQTAPAQAEENLADDGELVAVIAAAIAAAEGT
                     TTDGFVVRSIRKVKRNRR"
     CDS             12235..12603
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63; E-value:
                     6e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_45"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.6e-20, bitscore:
                     63.0, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYTITVNGTAYEVTVEETGSVSAPAAAPKAAPKAAPAAAPKAA
                     APAAGAGAVKVTASVPGKVVKVAASVGQAVKAGDSVVILESMKMEIPVVAPQDGTIASI
                     DVAEGASVENGDTLATMN"
     CDS             12620..13768
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_46"
                     /sec_met_domain="OAD_beta (E-value: 2.4e-156, bitscore:
                     511.9, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSYVTETLSNLIHQTAFFNLTWGNYLMIAVACVFLYLAIKKGFEP
                     LLLVPIAFGMLLVNIYPDIMANPEDMSNGVGGLLHYFYILDEWSILPSLIFMGVGAMTD
                     FGPLIANPISFLMGAAAQLGIYAAYFLAIFLGFNGKAAAAISIIGGADGPTSIFLAGKL
                     GQSALMGPIAVAAYSYMSLVPIIQPPIMKLCTTEKERKIKMDQLRPVSKLEKILFPIVI
                     TIVVCLILPTTAPLVGMLMLGNLFRECGVVKQLTETASNALMYIVVILLGTSVGASTSA
                     EAFLNADTLKIVVLGLVAFAIGTFGGCMLGKLLCKLTHGKINPLIGSAGVSAVPMAARV
                     SQKVGAEADPTNFLLMHAMGPNVAGVIGTAVAAGTFMAIFGV"
     CDS             13911..15323
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: PYC_OADA"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: HMGL-like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg44_47"
                     /sec_met_domain="HMGL-like (E-value: 2e-46, bitscore:
                     150.5, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 2.3e-58, bitscore:
                     189.1, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELEKKPVKIVETILRDAHQSQIATRMTTEQMLPIVDKLDKVGY
                     HAVECWGGATFDASLRFLHEDPWERLRKLRDGFKNTKLQMLFRGQNILGYRPYADDVVE
                     YFVQKSAANGIDIIRIFDCLNDLRNLQTAVSAANKEKAHAQVALSYTLGDAYTLEYWTD
                     IAKRIEDMGADSICIKDMAGLLLPNKATELVTALKETVKIPIDLHTHYTSGVASMTYLK
                     AVEAGVDIIDTAMSPFALGTSQPATEVMVETFKDTPYDTGFDQKLLSEIADYFRPIRDE
                     ALDSGLLNPKNLGVNIKTLLYQVPGGMLSNLTSQLKEQHAEDKFYDVLEEVPRVRKDLG
                     EPPLVTPSSQIVGTQAVFNVLMGERYKMVTKETKDILLGKYGATVKPFNPEVQKKCIGD
                     EKPITCRPADLLDNELEKLESEMAQYKEQDEDVLTYALFPQVAMDFFKYRQAQKTKVDE
                     KAADKKNGAYPV"
     CDS             15435..16916
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HI0933_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_48"
                     /sec_met_domain="HI0933_like (E-value: 1.5e-128, bitscore:
                     420.8, seeds: 46, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLPEVHIYIDRSEAETWNHDEIDNLQGKINTGEYSMSKVIIIGGG
                     AAGMMAGVFAARNHHEVHILEKNEKLGKKVFITGKGRCNVTNACDTEELFPAMMSNPKF
                     LYSSFYSFTPQDVMEFFEKAGVPLKVERGNRVFPQSDHSSDIIRALERELKKAGAKIHL
                     HTAVQEIVKKPVTESVTDSVNTLESEATLTESGSDAGKSRKGKKSSDIQQEKITGVILT
                     DGTFMEGDAVIVATGGFSYQSTGSTGDGYRFARELGLKVTDIAPSLVPLKTKEDYIPKL
                     QGLSLKNTGLTIKNGKKVLYEDFGEMMFTHFGVTGPMILSASAHIGAKLAKAPNGELSA
                     YLDLKPALTREQLDARILREFEAGPNKQFKNVISVLFPSSLTPVMLELGGIPAEKKIHD
                     ISREERQHFIDLIKAFPFTITGMGEFKEAIITRGGVSVKEINPGTMESKKISGLYFAGE
                     VLDLDAVTGGYNLQIAWSTAYLAAQAIRYCSLRSQ"
     CDS             17079..17750
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Cytidylate_kin"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_49"
                     /sec_met_domain="Cytidylate_kin (E-value: 1.8e-77,
                     bitscore: 251.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGCNIAIDGPAGAGKSTIAKKVAKELSFIYVDTGAMYRAMALYLL
                     NHGVNGENQEEIEAVCSGADISIEYKNGEQIVILNGENVNAMIRTEQVGNMASKSSANP
                     KVRAHLLKLQRTLAEKNDVVMDGRDIGTTILPNAEVKIYLTASADTRAKRRALEYEQKG
                     ESFDLDQIRKDIIERDERDMNREISPLKQADDAVLVDSSEMGIDQVVDAILDVYNKKIQ
                     K"
     CDS             17939..18817
                     /locus_tag="ctg44_50"
                     /transl_table=11
                     /translation="MKVKVAETAGFCFGVKRAVDKVYELIDTEQKPIYTLGPIIHNEGV
                     VADLEARGVHVITEADLDFPDDTLQNGTVVIRSHGVGKAIYDKLKEKNISYVDVTCPFV
                     LKIHRIVEKESLAGNHIIIIGDKDHPEVQGICGWCQGPYTVIRNKEEAEVFVPPKGKKI
                     SIVSQTTFNYNKFKDLVEILCKKRYDNNVLNILNILNTICNATEERQREAKNIAGEVDT
                     MLVVGGRHSSNTQKLFEICKKECGNTYYIQTPVDLDSEMFQCSSYVGITAGASTPNKII
                     EEVQEHVRIKF"
     CDS             18798..19874
                     /locus_tag="ctg44_51"
                     /transl_table=11
                     /translation="MSELSFEQMLEDSVKTIRNGEIVQGTVIDVKEDEIILNIGYKADG
                     IITKNEYSNDASLVLTDAVHVGDTMEAKVLKVNDGEGQVTLTYKRLAAEKGNKRLEEAF
                     ENQEVLKAPVTQVLDGGLCVNVDEARVFIPASLVSDTYEKDLSKYADQEIEFVITEFNP
                     RRRRIIGNRKQLLLAEKAEKQKELMERIHVGDTVEGTVKNVTDFGAFIDLGGADGLLHI
                     SEMSWGRVENPKKVFTVGDKVKVLIKEINGEKIALSLKFPEANPWLTAAEDFAVGNVVK
                     GKVARMTDFGAFVELAPGVDALLHVSQISREHVAKPADVLSIGQEIEAKVVDFNGEDKK
                     ISLSMKALEAPAEEAAEE"
     CDS             19902..20180
                     /locus_tag="ctg44_52"
                     /transl_table=11
                     /translation="MNILDFYKKENLPEGYVDLPTVVKTISDMVRELPFWCAMVELMNK
                     ISSENDSNIVTQKWKELLLKLAKSYVKILEPDAKEKCIEILATLQSN"
     CDS             20691..21074
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyoxalase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg44_53"
                     /sec_met_domain="Glyoxalase (E-value: 1e-20, bitscore:
                     66.2, seeds: 82, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLSKIHHIAIIVSDYEAAKDFYVNKLGLSVIRENYRPERKDWKL
                     DLRVNEHTELEIFAEENPPKRVNRPEACGLRHLAFCVESVEQTVNELAEVGIECEPIRV
                     DDYTGKKMTFFHDPDGLPLELHE"
     CDS             21487..21849
                     /locus_tag="ctg44_54"
                     /transl_table=11
                     /translation="MKRWRDEPTEENFWGVVLAYAGVKFKTYSGLPFSYEIKKGRNGEY
                     TKELWIDRREKSKSLAWSSIFLALGNIKEEVVERPKALGDIRGVTYIYGMFYRFGLIDV
                     PDEVKEKMGHPKTRKK"
     CDS             21949..22272
                     /locus_tag="ctg44_55"
                     /transl_table=11
                     /translation="LKKTEPEYYPPVENLLDLIYEHYTENNPVEKNTVAGKTAKAKEKE
                     LEEWLRGLDGMDRLVDDYVGDKIPLWEKIMDRQGTVCCAWEKTAFEEGLKVGIRLMMEV
                     YSL"
     CDS             complement(22339..22530)
                     /locus_tag="ctg44_56"
                     /transl_table=11
                     /translation="MKAHKYWSLGALACMAGCFYTGCKKLMQAHKYFACGSLVCMGMAI
                     YSGHKIAPKKKKAEKPEK"
     CDS             complement(23060..23821)
                     /locus_tag="ctg44_57"
                     /transl_table=11
                     /translation="MYHQLYNTLETYEYTGNFLNLLSSDIMDEKGNDLSADTNGKLYVS
                     LSAKKGIVIKDEQTTAKHDISGNLTMHPSGAWGLAYSYSNDTEKITFQDGNILKEPWIL
                     TSMDDDEVRTGIFKQVSLIEIGNEHIMVYGCLVGDDAPYKIAVYDQDGNQQLLLGRDPS
                     DDSASFGYITGVAETANGYIATDGNARILYFWSKDGTLLGKIQCSDIFGTRYPWLEDIK
                     VADDGSAMLLMTQKREDESASELMVFRLTGF"
ORIGIN
        1 catgacagtg ctgcgatcgc tgcatatctg gaaggatgcg gactggatgc catccatgta
       61 tccagagctg ttcacatccg cgatgaattt atgtgggcac cgacagtcac acacggcggt
      121 ttctccgctt ctcaggtaga agagatcaaa cgtgccgtat ctatcccggt gatcacagta
      181 ggacgttata cagaaccgca gtttgcggaa ttaatggtaa aagaaggacg ctgtgacctg
      241 gttgcattcg gacgtcagag ccttgcagat ccttatatgc cattaaaagc gcaggaagaa
      301 agactggagg atatgatccc atgtatcgca tgtcttcagg gctgcgtggc aaacatgtat
      361 gcaggaaacc ctgtatgctg tcttgtaaac ccattccttg gacatgaagc tgagggcatt
      421 gctcctgcag aaaaagcgaa aaaagtaatg gtaattggcg gcggtgttgc aggtctttgc
      481 gctgcattta tcgcacagga aaaaggtcat caggtaacac tttatgaagc aagtgataaa
      541 cttggcggaa acatgcgtct tgctgcttat cctccgggaa aaggcgacat cacaaacatg
      601 atccgcagct atatcgtacg ctgccagaaa gcaggcgtaa caatcaaaat gaatcaggaa
      661 gtaactctgg atcttatcag ggaagagaaa ccagacagcg taattgttgc ttccggttcc
      721 agaacactga tccttccgat cgaaggtatc gacaatcctg caattatcca tggctctgat
      781 ctccttgacg gaaagagagc agcaggaaag aaagtactgg ttgtaggcgg cggaatggtg
      841 ggatgcgaga cagcagcatt cctcggtgag cagaaccatg atgtaacagt cattgagttc
      901 agagacactg taggtgccga cgtgatccac gagcatagag tttacctgat gaaagatttc
      961 gaagattaca agatcaaaga gatcacaggt gcaaaggtat gcaaattcta tgaggacggc
     1021 gtagagtacg agacagcaga cggacagaga catgaatcca gaggctatga ttctgtcatc
     1081 ctctccatgg gattcagaaa ctacaaccca ttcggcgaag agatcaaagc tatcgtaccg
     1141 gatacctatg tgatcggcga tgccacccgc gcaagaagag cacttgatgc tacgaaagaa
     1201 gcgtatgagg tagcttccac attatgatga tatcagggtc aaaagttcaa aaagtcgttc
     1261 gtgcttgcac gataagattt ttgaacctgg gacccgccaa acatgagaaa gtagcgattt
     1321 acgcagtaaa tcagcgaatt tcgaatctta taatttattc gttttatagt tgcagttaag
     1381 agacgctgta tgatattatc agcggacagc agcttgaaaa tgattttaca aaaaaattca
     1441 ggaggcaaac aggaaatgga acagagaatt aaaggaacaa caggattaat ggcacttatc
     1501 ggaagcccgg taggacactc aggatcaccg gcaatgtata acttcagctt ccgtcatcat
     1561 aaccttgact atgcttacat ggcatttgac atcaaggaag accaggttcc ggctgctctg
     1621 gatgcaatcc gtcttttcaa aatgagaggc gcaaacgtaa ctatgccatg caagaacgaa
     1681 gttgcaaaac acatggatga gctttcacct gcagcaagaa tcatcggtgc agttaacaca
     1741 atcgttaatg aagacggcaa attagtagga catatcacag acggtatcgg atttgtccgc
     1801 aacttaaaag aacatggcgt tgatgtgaaa ggcaaaaaaa tggtagttct cggtgcaggc
     1861 ggtgctgcaa cagcaatcca ggtacagtgt gcattagacg gtgcagaatc catttctatc
     1921 ttcaatccga aagacccatt ctttgcacgt gcagagtcca cagcagagaa actgagcaaa
     1981 gaaacaccgg attgtaaagt ttctgtattt gatctggcag atgaggcaaa actgaaagaa
     2041 gaggttgcaa acgcagacat cctcgtaaac gcaacacttg caggaatgaa acctcacgaa
     2101 gagcttactc tgattaaaga taaatccatg ttccgccctg accttgtagt agcagacgtt
     2161 gtttacaatc ctgctgaaac aagaatggta aaagaagcca aagaagcagg ctgcaagctt
     2221 gcaatcggcg gaaaaggaat gctgttatgg cagggagctg cagcttacaa actctacaca
     2281 ggactggaaa tgccaacagc tgaataccag aaattccagg aagaaaacga aaacaagtaa
     2341 taataaccta ggagaccaaa atgaaacaga aaacaaacaa aatgctcatt ttcacctccc
     2401 ttgcagcata tttcacttat ttcatccatg gaatcggtgc ttctatcctg gggcagtaca
     2461 aaccggagtt tgcagctgcc tggggtgcga agcccctggc cgatggcaca ctggatgtaa
     2521 gtatggtagt atctgtaatt gcagcacttg gactggggcg tctgatttct cttcctttct
     2581 ccggccctct gtctgacaaa tacggaagaa aactgagcgg aattatcggt gtgctctgtt
     2641 atgtggcata cttctttgga atggctaatt ccacatccat ggcaatggga tatgcatttg
     2701 cagtgatcgg cggaatcgcg aactctttcc tcgatacctg cgtaagcccc acctgtatgg
     2761 aaatctatgt aaacaacccg tcagtagcca acctgtttac aaaattttcc atctgcctga
     2821 gccagttcct gcttccattc ctgatcggaa tcgtagcatc tgcaaatatg tcatataaga
     2881 caatctttat tgttgcaggt attgcaatcc tcattgacgg aatcctgatc ctgatcctcc
     2941 cttttccggc gagagagaaa aaagtacagg ataaagctga taagaagaaa tccggacaca
     3001 agatttcccc tgcagcgatc gcagcaatcc tgatcggatt caccagctcc tcaaccttta
     3061 tgttatggct gaactgtaat caggaacttg cccgttccta cggtatggca gacccttcaa
     3121 agatccagtc cctgtatgcc ctgggaactg caactgccat ccttgcaaca gcagcattta
     3181 tcaaaaaagg tctgaaagag attaacgtcc tgatcctcta tccgttaatc tccactatca
     3241 tgctgctcct atgttacttt atccaggccc cgtttatttg cctgataggt ggctttgtga
     3301 tcggatatgc aggtgcaggc ggtgttctcc agctggcagt ttccacaaca gcagagttct
     3361 tccctgagaa taagggaaca gcaacctcac tggtaatgat cgcatccagc atcgcgaact
     3421 acacaatctt aagccttgca gggtacatta ccaaagtggg cggaagcagt gctccgagaa
     3481 tgattcttct tctgaatatg gcagtgacca tcatcggtat cctgctcgct ctttttgtaa
     3541 agaaaaacag aaatcagtaa ggcagtgtgc caacaagttg atttcctgaa taatctcgca
     3601 tctaaatttc ttattttcgc gttgttgtcg ggtgtcgtag ctaccgctat gcctccttcc
     3661 tacgccttga aataaaaaat tattaaaatc caatccaact gaagatatgt ttggacgtta
     3721 caagcttcaa attttttccg gtcggattgg attttattaa aatccggatt gtctaaaaat
     3781 taacaaaaaa gatggaatat acaagataaa atatagaagt aatctaacaa ttcattgaaa
     3841 aggagaattt gtatggcaaa tacaagaaca caaagaagag aaaatgaact gccctacatc
     3901 ccctttggac catttcagat aagacttcca tttatacact acaagataga atctgttgag
     3961 ttcattcagg gtctgatcct gggcgtaaca gcactggcag ctgttcccta tctggagcaa
     4021 tatctggggc ttccttatga gctggcgtgg agctgtgtaa ttattgaaac cttcctttat
     4081 ctgcttcaca gcctgctcgg cgatccggta gtaccggggt ggatcacacc cacactgccg
     4141 ctgaccattg tatttctgga aggcttcccc atgggaaaag aacgaataca ggctatgatc
     4201 gcactgcaga tgctggtagg tctggtattt atctttatgg gtgtgaccag actggcggat
     4261 aaatttgttc atgcagttcc caattctgtc aaaggcggaa tccttcttgc agcacctgtt
     4321 acagttatgg caggacagct gggtgagaat ggaaatatgc acaaatatcc tctggctatt
     4381 gttgcaggtg taggcctcct gatcctgatt agcttctctg acaaatatca ggagaagaga
     4441 aaaacaaata agtttcttga tctggttgcg agatacggaa atcttttccc atatcttatc
     4501 gcaatggtag taggacttct ggttggcgaa ctggatgccc cgggactgga gattggtacc
     4561 tttatcaaga ttcctcagtt caaagatatc attgatcagg tgagtatttt cggcgtaggg
     4621 attcctcctg catctatgtt tatcaaagca ttgccgctgg cgctggtgtg ctatgttatt
     4681 gcatttggtg attttgttac tacagagacc cttgtatcag aggcacgtca ggcaagagat
     4741 gatgagtata ttgatttcaa ttccagccgt tccaatctgg tcagcggtct gagaaacctg
     4801 atcctgtcca tcatcgcacc atttcctcct ctttccggtc cgttatgggt tggaatgact
     4861 gtatccgtat ccatgcgtta taaagaagga aagaaagcaa tgaagtctct tctcggagga
     4921 atggcttctt tcagactggc cacattctta agtgtgctga tcattcctgt agtaagtttc
     4981 ttccgtccca tcttcggagt aggctcttcc attactctga tgttccaggc atttgtatgt
     5041 gcgagaattg gtatggatta ctgcaagagc gacagagaca agatgatcgc aggcgtaatg
     5101 gcagcagtcc tcgcaaccca gggaaccgca tgggcatctg catgggcact ggcagttggc
     5161 ttcggactga atatcttcct gtccaactgg aatccccttg agaaaaaata atataagcaa
     5221 aaaccaagaa gaacagccgg gattcggggc tgttcttctt ggttttcatc aattattatt
     5281 ttaaggagtc ataattatta aattcaaatt ctgtaacaat ctgttgacga atatgagtga
     5341 tatcagctat aggcaagaat aacatctgat atcacatcat tcatcaacag atcacagact
     5401 gctgtgaatg atatccagca cctgttttaa ttcatgcaca ccgacctgtc ccggagcaga
     5461 agctttggaa gcagcaccga aagtgagagc ggagccgaat gtctcacctg tcagacggct
     5521 tacaacgcct gttcctgcca tggacatggt aatgatcggg cggtctgcat atttctcaga
     5581 catttccaga gtagcagaga ggagtgtaag aacatcctgt ttgcaggtcg gcataacagc
     5641 cattttcgga atatcagcac cgaaatcctg catcatacga agacgtctga taatctcctc
     5701 cttctcagga gtcttaaaga aatcatggtt ggaagcaatt accttcacac ctgcctcgtg
     5761 agcagcattg atgattgtct taacaacttc atcacctgta aatgcttcta catcaattaa
     5821 atctacataa ccgctctgag cagctgcaat atttaaagca gcatagtcat ttacagaaat
     5881 ttctttctca ccgccttctt tggaagtacg gaatgtaagg agaacaggaa tgtcttttaa
     5941 aacttcctga agctctttag cggtttctaa tactttctca gtagcaaaga catcatcaaa
     6001 ccagtctaca cgccactcaa ctacatcaac aggaagagta gtgatctttt tggcttcttc
     6061 gagaatgtct gtttttgttt ttcctacgat gggaacgcag atcttaggtc tgccctcgcc
     6121 gatcacagtg ttttttacct gaactgtgtt catctgttta tcctcatatt ttctgttgta
     6181 ttatagtagt tccggattat tatggaactg ttataagaat aaccgtaaca taaccgcatg
     6241 atcaacagct ttttgaagca aactgcagga tatgtacatt ctgcgcggag taatatatca
     6301 gtacatctcc tgcagtacgc cgaaaagcgg tatatatcaa atattatgtg cggaaagatc
     6361 agtgaaatga tctgttctgc atcacaatat gagatatcca tactgaagat accatcaggt
     6421 atcagtcatc ataggagatg tgaagaatct ctttcatatg ttcgataggc attggttcgc
     6481 ctgtccataa ctcaaatgca gcggaaccct ggaataacat cattcccaga ccattcatag
     6541 tcttacatcc aacttccttg gccatggaac gcatctttgt ttccagagga gagtaaggaa
     6601 catcaataac gattagctca ggacggaagt aagacttgtc cggaacaacg gactggcctt
     6661 ccagtggttt cattcccaca cctgtagcat tgacaaagat aaaactgtta tccatctcag
     6721 ctttcagttt atcaagatct gccagatcat aaagaactgc atggcaggag gtctttgtgt
     6781 tgatcttctc tactgtggat actgcacgat cccagaattc atccctgcgg ttgaagattg
     6841 tgatctcggc aacgccgtcc aaagcagcct ggatctcgat agcagtggca gcaccgcctg
     6901 caccgacgat agtcattttc tttccaatca catcaatatc attatctttc agggcagaca
     6961 taaacccgat accgtcagtg atatgacctg taagatgacc gttgtcattt acgatcgtgt
     7021 taactgcacc gcataattct gctgcaggag aaagctcatc caggtatttt ccaaccagag
     7081 ttttgtttgg catggaaaca ttggagcctc tcattttcag agtgcggatt gcttttactg
     7141 catcctcaat ttcatctgcg ccaacctcga aagcaaggta agcgtagtca tacccgagtt
     7201 ttgcaaaagc ctcattctgc attgcaggag agctggagtg acggatcggg taagccatca
     7261 gaccgattaa ttcagtatgt ccggtaattc tttcagccat tataatatcc cctttcgtat
     7321 tttgttgtaa aggtttttat tgaaggtatc ccatctgagt cagtgtatta aggatatttc
     7381 ttccttccag agttccgtcg atgatctttc ttgcacgttt gctgtctccg atgttcagga
     7441 tctcaacatc atcagaaaca aaagcatcgg aaagctctgc gaaaagctgt ccctgagctc
     7501 tcataccaag gcatacgaat ccgtagtcaa atggaagctc gcgttcacct tctgcatctc
     7561 ttacaaggaa agagctgtct tttacttcct gaagagctgt ctttgtaagc tgggtcacat
     7621 gatgtttctt catctggtcc ttcatgtcat tctttgtaac aggatccagg tcacgtccga
     7681 tctgatccat catttccaca atagaaatct cagcatttct tgctgcaaag aattccacaa
     7741 catcaagacc aacagcaccg ccgcccacaa caacaacctt cttgcctgtc atatcttccg
     7801 gatagtcatt gatgtgattg atcattccca ggatagaagc aaccttgctg ccttctttgt
     7861 caatgcggtc gtgaagtccc ctgatcggag gaagcagtgg tgcggaacct gtggagctta
     7921 cgatcaggtt cggatggaac ttgcggatat tttccggtgt tccttctgtg tttgtgaaga
     7981 tataaagatt ctcaagctgc tctgctcttt gaatcagata gttcgggaaa tcagccagac
     8041 gcttctttgc aggaatctta gagatcacag aagcaagacc gccaagagtc tcaccttttt
     8101 ccagaaggaa ggtattacag cctacttctg cggctgtaca ggcagcttcc agtccggcag
     8161 taccgcctcc gattactaca acgttacagt tcttgttcac tttctgattc ttataaacat
     8221 caccttccag aacagccggg tttacagtac agcggatcgg acggttaaag ccgattctgt
     8281 ttcctgcaca tccgatgtta caggagatac atttgcgaag gtcacattct ctgcctgtag
     8341 ctactttgtt cacccatgca ggttctgcga taagaccacg tcccataccg atcaggtctg
     8401 catcgccgtc agcgaggatc tgctcggcaa ccttcgggtt acggatattt cccatggaga
     8461 tacatggctt gccgaatttc tctctgacag ctttaggcat ataggaacgc catccgtctt
     8521 tcatgtagtt ggcatcgatc tgatactgga tagaaccgtt taaaccgcag gaaacatcga
     8581 agatatcaac ttcatcctga acatattcca gatattcaag agtatcctca agagtgttgc
     8641 cgccttccat cagctcatct gcgctgagac ggagcatgat cgggaagaaa ggtccgacct
     8701 gttttcttac ttcttcaatg accatacggc agaaacgtgt tctgttttcc acagatccgc
     8761 cgaactcatc tgtacgtttg tttgtaagag gagagaggaa ctggctgatc agataggaat
     8821 gtcccgcatg gacctctacc gcgtcaaaac ctgcagcctg ggctctcttt gcggcctcgc
     8881 cgtatttctt tacaatgtga tggatttctt ccactgataa cggacgcggg atttctccgc
     8941 cttctttgga cggaatatca gatgcggaaa ccggctgcat atttgtacgt gcggaaacag
     9001 cggaagcacc tgcgtggttg atctggatcg caatacaggt accatatttg tggatctctt
     9061 cacagaattt gtacagacgc ggcagatagt tgtcgtggtc aatacgaagc tgagtagttc
     9121 cgttggaacc ctgcggagaa tctacgcttg cattctctac gatgatcaga cctgtgccgc
     9181 ctttggcacg ctctttataa taattaatgt gaagaaaact catttcgccg ttctgttccc
     9241 cgtaattggt tcccataggc atcataacga tacggttttt gatagtcata ttttttactg
     9301 tgagtggtgt gaaaatatgc tggtaattgc ttttcattac gtctttcctc ctgaaatttt
     9361 ctgttggatc tataattgtt cagtgcttta gctgtggcct gaatttcttt gatgtgttaa
     9421 ttatataacg ggataatcca taaatctaat tgataattcg tgctatataa taaaaaacat
     9481 ctatggtttt ccgtgcactg tccgcgtatt gaatgaaagc attcgcaact gcatccacat
     9541 catgggaaaa tcctgctgaa cctgtatggc tatagtattt tttcgccgag ccgcgctgag
     9601 acttttatac ctgtgtagtc ggattcgtag acaagtgagt ggtatagtta cttcaaacac
     9661 gctctggtgt gccgacaagt tgattcttga aacagtcttg caggatagaa ataagaaatt
     9721 cagacgcagg attgttcgag aaatcaactt gtcgatacac tggtttgcgg gagagggtga
     9781 aatacaggac aatacaaaat aaccgtaata ccctctatta aataggaaga aatgctcaaa
     9841 aaaacaaaat ttggagaaac ctgacaaatt tttctgctat atttttaacg aaaatgacaa
     9901 ataaatgttg aaattttctg ccggaaaagg taaaattaaa atcggctaaa tttttgggtt
     9961 aacttttaaa tattctcata aagatggagg gcaaacaaga atgagtaatg caacacaaag
    10021 cttagcaggc acaagaatta cttctttgct tgacgcaaac agttttgtcg aaatcggaca
    10081 gggtgtaaca gccagatcca cagatttcaa catgactgca aacaaggcac catctgacgg
    10141 tgttatcacc ggatatggtg tgatcgatga caaactggtt tatgtataca gccaggatgc
    10201 atctgtatta aacggtactg ttggtgaaat gcatgcaaag aagatcacaa gactttatga
    10261 tcttgccatg aaaacaggcg ctccggttat cggacttgtt gactgtgcag gtatccgtct
    10321 tcaggaagca acagacgcac tggaagcttt cggacagatc tatctgaaac agacactggc
    10381 atccggtgtg atcccgcaga tcacagcaat cttcggaaca tgcggcggtg gtatggcagt
    10441 tatcccgtcc ctgacagatt tcacattcat ggaatccaaa aaaggaaaaa tgttcgtcaa
    10501 cacaccaaac gcactggaag gaaacaacac agacaaatgc gacacagcag cagctgattt
    10561 ccagagcaaa gagacaggtg tgatcgatgg cgttggtaca gaggatgaga ttcttggcca
    10621 gatccgttcc ttagtatcac ttcttccttc taataatgaa gacacagaca attacacaga
    10681 gtgtacagat gatcttaacc gcgtatgcgc agatcttgca aactgtgcag gtgacacagc
    10741 aatcgcactt tcccagatcg ctgacaacgg tgaattcttc gagacaaaag cagactatgc
    10801 aaaagacatg gttacaggct ttatccgttt aaacggcgct acagtaggtg ctgttgcaaa
    10861 cagaagcgaa gtatatgacg cagaaggtaa gaaagtagaa acatttgacg gaagcatctc
    10921 tgcaagaggc gcaagaaaag cagcagattt cgtgaaattc tgcgacgctt ttgatattcc
    10981 ggtacttaca cttacaaacg caacaggctt catggcaacc ttatgcagcg agaagatgat
    11041 ggcgaaatcc gtaggtgaac tggtagctgc attcgcagat gcaactgttc cgaaggtaaa
    11101 tgtgatcatc ggcaaagctt acggtacagc ttacgtggca atgaacagca aatctatcgg
    11161 tgcagacctt gtatatgcat gggataacgc agagatcggt atgatggatg cttccctggc
    11221 agccaagatc atgtatgcag atgcagatgc tgctgaactg aatgaaaaag ctgctcagta
    11281 cagagagctt cagaatggtg ttgcttccgc agcagcaaga ggctatgttg acactgtgat
    11341 cagcccggct gacacaagaa aatatgtaat cggtgcattt gagatgctgt tcacaaagag
    11401 agaagatcgt ccgtctaaga aacatggaac ggtctaagcg gggtgacgca tatgaaaatg
    11461 atcaaaaaaa taacttctgt attcatgaca tttctcgtaa tggctgcgct ggtgattggc
    11521 agcacctctg tggtatttgc cgcagataag gttgatgata ctgttaagtc cacactggta
    11581 actacagcag aaggactgac agatgccatt gtccagctta aagatgaaga aatcgagaat
    11641 tacatgagtt caggagatga ctttacaaca agtgccatgc agtcctggca gacatccaag
    11701 gatgaacttg gcgcaaagaa ggacagcaat ggtgaaacta ctgtaacttt caaagatgat
    11761 cagtacacag ttactgttcc tcttaaattt gagaaagcag aagcaaactt tgtatatgtc
    11821 tttgactcac agggaacacc gacttccatg tctgtagatg tacagtatgg tatgggcaag
    11881 acccttcaga gagcaggtct taatactctg atgggtattg gaactgtatt cgtaatgctg
    11941 attttattaa gccttctgat ttctctgttt agatttattc cgaatccgga agcaaagaaa
    12001 gcagcagaag caaaagcagc caaagctgca aaagaggcag aggcagcagc catcgcacag
    12061 acagcacctg cacaggcaga agagaacctt gcagatgacg gagagctggt agctgttatc
    12121 gcagcagcta tcgcagcagc agaaggaact acaacagatg gcttcgtagt tcgttccatc
    12181 cgtaaagtaa aaagaaatag aagataattg tcatttattt aggaggattt taaaatgaaa
    12241 agctatacaa ttacagtaaa tggtacagca tatgaagtaa ctgttgaaga aacaggaagc
    12301 gtatccgctc ctgcagcagc tccaaaagca gcacctaagg ctgcacctgc agcagctccg
    12361 aaagcagcag ctcctgcagc aggcgccggc gcagtaaaag taactgcttc cgtacctggt
    12421 aaagttgtca aagtagcagc aagcgttgga caggcagtaa aagccggaga cagcgtagtt
    12481 attcttgaat ccatgaaaat ggaaatccct gtagtagctc ctcaggacgg tactatcgca
    12541 agcattgatg ttgcagaagg tgcctctgta gaaaacggag atactttagc aacaatgaac
    12601 taagacggga ggtagtcaaa tgtcttatgt aacagaaaca ttgtccaacc tgattcacca
    12661 gacagcattt ttcaatctga catggggcaa ttacctgatg atcgcagtag cctgcgtatt
    12721 cctttacctt gctatcaaga agggattcga gccgcttctg cttgttccta tcgcattcgg
    12781 tatgctgctt gtaaatatct atccggacat tatggcaaac ccggaagata tgtccaatgg
    12841 tgtaggtgga cttcttcatt atttctacat ccttgatgag tggagtatct taccatccct
    12901 gatcttcatg ggtgtaggtg ccatgacaga cttcggtccg ctgatcgcaa acccgatcag
    12961 cttcctgatg ggtgctgcag cacagcttgg tatctatgca gcttacttcc ttgcaatctt
    13021 cctcggattc aacggaaaag cagcagcagc tatctccatc atcggtggtg ctgatggccc
    13081 gacttccatt ttccttgcag gtaaacttgg acagtctgca ctgatgggac cgattgcagt
    13141 ggcagcatat tcctatatgt cactggttcc gatcatccag ccgcctatca tgaaactctg
    13201 cacaacagag aaagaacgta agatcaaaat ggaccagctt cgcccggttt ccaaactgga
    13261 gaagatcctg ttcccgatcg ttatcacaat cgttgtctgc ctgatcctgc ctacaacagc
    13321 tccgctggtt ggtatgctca tgcttggtaa cctgttcaga gagtgcggtg ttgtaaaaca
    13381 gctgacagaa acagcttcca atgccctgat gtatatcgta gttatccttc tgggtacatc
    13441 cgtaggtgct tccacaagtg cagaagcatt cttaaacgca gatactctga agatcgtagt
    13501 tttaggtctt gttgcattcg caatcggtac attcggcgga tgtatgcttg gtaaactgct
    13561 ctgcaaactg actcatggaa agatcaaccc gctgatcggt tccgcaggtg tatccgcagt
    13621 acctatggca gcccgtgtat cccagaaagt gggtgcagag gcagatccta caaacttcct
    13681 tctgatgcac gcaatgggcc cgaacgttgc cggtgttatc ggtacagccg tagcagccgg
    13741 aacattcatg gctattttcg gagtataacc aaatcaagca agctatcttg cttgtatcag
    13801 gaggagtgca actccttctg ataagctgcg gagcagctat ttggttatga gcaagtagcg
    13861 aagcggattg cgaatatccg attaaacaga actataaagg agatttaata atggcagaat
    13921 tagagaaaaa acctgttaaa attgtggaaa ccattctccg tgatgctcat cagtcccaga
    13981 tcgcaacacg tatgaccaca gaacagatgc ttccgatcgt agataaactt gacaaagtcg
    14041 gctatcacgc agtagagtgc tggggcggtg caacattcga tgcatccctt cgtttcctcc
    14101 acgaagatcc atgggaaaga cttcgtaaat tacgtgacgg cttcaaaaac acaaaacttc
    14161 agatgctttt ccgtggacag aacatccttg gataccgtcc atacgcagat gacgttgtag
    14221 aatacttcgt acagaaatct gctgcaaacg gaatcgacat catccgtatt tttgactgcc
    14281 tcaatgacct tcgtaacctg cagacagcag taagcgctgc aaacaaagag aaggctcatg
    14341 cacaggtagc tctttcctac acattaggag atgcttacac actggaatac tggacagaca
    14401 ttgcaaaacg tattgaagat atgggcgctg attccatctg tatcaaagat atggcaggtc
    14461 ttctccttcc aaacaaagct acagagcttg ttacagcatt aaaagaaaca gttaagatcc
    14521 cgatcgacct tcatacacat tacacctcag gtgtagcttc catgacttac ttaaaagcag
    14581 tagaagcagg tgtggatatc atcgatacag caatgtctcc atttgcactg ggaacatccc
    14641 agcctgcaac agaggttatg gttgagacat tcaaagatac accatatgac acaggatttg
    14701 atcagaagct tctctccgag atcgctgact acttccgtcc gatccgtgac gaagctcttg
    14761 acagcggact gctcaatccg aagaaccttg gtgttaacat caaaacttta ctgtaccagg
    14821 taccgggcgg tatgctctcc aacctgactt cccagctgaa agaacagcac gcagaagaca
    14881 aattctacga tgttctcgag gaagttccgc gtgtacgtaa agaccttggt gaaccgccac
    14941 ttgttactcc gtcttcacag atcgttggta cacaggctgt attcaacgta ctcatgggcg
    15001 agagatacaa aatggttaca aaagaaacaa aagatatcct gttaggaaaa tacggcgcaa
    15061 ctgtaaaacc gtttaatccg gaagtacaga agaagtgtat cggcgatgag aaaccgatca
    15121 cttgccgccc tgcagacctt cttgacaacg agcttgagaa acttgagagc gaaatggctc
    15181 agtacaagga acaggatgaa gacgtattaa catacgcact gttcccacag gtagctatgg
    15241 acttcttcaa ataccgtcag gctcagaaaa caaaagttga cgagaaagca gctgacaaaa
    15301 agaacggagc atatcctgta taattgatca gtaattaaat atgtccaaac gaaaaaagga
    15361 gcttgcgtaa gcaggctcct ttgcgttatt atgaaagaat atgatacccg ggaatataat
    15421 gtgccaatgg ttatatgctg ccagaggtac atatctatat tgatcgtagc gaagcggaga
    15481 cgtggaacca tgatgaaata gacaatctgc agggtaaaat aaatacagga gaatattcca
    15541 tgagcaaagt tataataatc ggcggcggag ccgccggaat gatggcgggg gtttttgcag
    15601 cccgtaacca tcatgaagtt catatattag agaagaacga gaaactggga aagaaagtct
    15661 tcattacagg aaaaggcaga tgcaatgtga caaatgcctg cgacacagaa gaactctttc
    15721 ctgcaatgat gagcaatccc aagttcctct acagcagttt ctattcattt acccctcagg
    15781 atgtaatgga gttctttgag aaagcaggtg tccctctgaa ggtagagcgt ggaaacagag
    15841 tattcccaca gtctgaccat tcttcagaca tcatccgcgc attggaacgt gaactgaaga
    15901 aagcaggagc aaagattcat cttcacactg ctgtacagga aattgtaaag aaacctgtaa
    15961 cggaatctgt aacagattcc gtaaataccc ttgaatcaga agctacatta acagaatcag
    16021 gatctgatgc aggaaaaagc agaaaaggaa aaaaatcatc tgacatacag caggagaaga
    16081 tcacaggagt catccttaca gacggaacct tcatggaagg agatgcagtc atcgtggcaa
    16141 ccggcggatt ctcttatcag agtaccggtt ccacaggtga cggataccgc ttcgcaagag
    16201 aactgggact gaaagtcacg gacattgctc cctcccttgt gccattaaag acaaaagaag
    16261 actatatccc taagcttcag ggactttccc ttaagaatac aggacttacc ataaagaatg
    16321 gaaagaaagt actttacgag gatttcggag agatgatgtt cacccatttc ggagtcacag
    16381 gtccaatgat cctctccgcc agtgcccaca tcggtgcaaa actggcaaaa gcaccaaacg
    16441 gcgaactgtc cgcatatctg gatctgaagc ctgcactcac cagagaacaa ctggatgcca
    16501 ggatcctgcg tgaatttgaa gcaggaccaa acaaacagtt caagaacgtg attagcgtac
    16561 ttttcccgtc atctctgact ccggtaatgc tggaactggg tggaatcccc gcagagaaga
    16621 aaattcacga catctccaga gaagaacgcc agcacttcat tgaccttatc aaagccttcc
    16681 ccttcacaat cacaggaatg ggtgagttca aagaagccat catcaccaga ggcggcgtct
    16741 ctgtcaaaga gatcaacccc ggaacaatgg aatcaaagaa aatctcaggg ctttacttcg
    16801 caggcgaggt actggatctg gatgcagtga caggtggata taacttacag attgcctggt
    16861 ctaccgcata tctggcagcg caggctatac gttactgttc actccgttca cagtaacggc
    16921 tatacagtaa gctgaaacaa gcagatgatg agtaccttgt agatggatta tatctatgat
    16981 atgattcagc tatacgttat ttaccgattc ataaacatca atcaataata aaacagagaa
    17041 aatctgtttg aataatagaa acaggaggaa ccacgaaaat gggatgtaac atagccatcg
    17101 acggacctgc aggagcagga aagagcacca tcgcaaagaa agtagcgaaa gaattatcat
    17161 ttatctatgt agatacagga gccatgtaca gggcaatggc tttatatctt ctgaaccatg
    17221 gcgtaaacgg agaaaatcag gaagagatcg aggctgtatg ttccggcgct gacatttcca
    17281 tcgaatacaa aaacggagaa cagattgtca tccttaacgg agagaacgta aatgctatga
    17341 tccgcaccga acaggtagga aacatggcat ccaaaagttc cgcaaacccg aaagtcagag
    17401 ctcaccttct gaaacttcag agaactctgg cagagaaaaa tgacgtagtc atggacggca
    17461 gagatatcgg cacaaccatc cttccaaacg cagaagtaaa aatctacctc acagcaagcg
    17521 cagacaccag agcaaaaaga agagcactgg aatatgaaca gaagggagaa tccttcgacc
    17581 tggaccagat ccgaaaagac atcatcgagc gcgacgaacg cgacatgaac cgcgaaatct
    17641 cccctctgaa acaggcagac gacgcagtgc tcgtagattc ctcggaaatg ggaattgatc
    17701 aggttgtaga tgctattctt gatgtgtata ataagaagat acagaaataa cggtcaggcg
    17761 gacagattat ctgtttcaga ctacgctatt tgcccgtcaa ctacctatca cctaaagtgg
    17821 tgctgcatca tagggtggtt gacagcaccc tttacagaca agatatactc atctgtaact
    17881 gtaaacttcc catgctatac agcaaacatt cttttacggg taaggaaagg atttatttat
    17941 gaaagttaaa gtagcagaga cagcaggctt ctgcttcggc gtcaaacgtg cagtggacaa
    18001 agtctacgag ctgatcgaca cagaacagaa accaatctac actctgggcc cgatcatcca
    18061 caacgaaggc gtagtagcgg atctggaagc ccgtggcgtc catgttatca cagaagcaga
    18121 cctggatttc ccggatgata ccctgcagaa cggaacagta gtcatccgct ctcacggtgt
    18181 aggcaaagcc atctacgata agctgaaaga aaaaaacatc tcttatgtag atgtgacctg
    18241 ccccttcgtt ctgaaaatcc acaggatcgt ggaaaaagaa agccttgcag gaaaccacat
    18301 catcatcatc ggcgacaaag accaccccga agtacagggc atctgcggct ggtgtcaggg
    18361 accgtacacg gtgatcagaa acaaagaaga agccgaagta tttgtacccc caaaaggcaa
    18421 aaaaataagc atcgtgtccc agacgacatt taattacaac aaatttaaag atttagttga
    18481 aattctttgc aaaaagaggt atgataataa tgttttaaat attctcaata ttttaaacac
    18541 tatttgtaat gctaccgaag aacggcagag agaagcaaaa aacatagccg gagaggtaga
    18601 cactatgttg gtcgtaggtg gccggcacag ttccaatact caaaagctgt ttgaaatatg
    18661 taaaaaggaa tgtggaaata cttactatat acaaacacct gtagacttgg attctgaaat
    18721 gttccaatgc agtagttatg taggtattac agcaggggct tccaccccaa acaaaattat
    18781 tgaggaggtt caagaacatg tcagaattaa gttttgaaca aatgctggaa gattccgtaa
    18841 agactatcag aaatggagag attgtacagg gtactgtcat cgatgtaaaa gaagatgaga
    18901 ttattctgaa tatcggttat aaagcagacg gtattatcac aaagaacgaa tactctaacg
    18961 atgcaagcct tgtactcaca gatgctgttc acgttggaga cacaatggaa gcaaaagttc
    19021 tcaaagtaaa cgatggagaa ggtcaggtta ctcttactta caagagactg gcagcagaga
    19081 aaggcaacaa acgtcttgaa gaagcatttg agaatcagga agtattaaaa gctcctgtaa
    19141 ctcaggtact tgacggtgga ctttgtgtaa acgtagacga agcaagagta ttcattcctg
    19201 caagtctggt ttccgacaca tatgagaaag acctttccaa atatgcagat caggagatcg
    19261 aattcgttat cacagaattc aacccgagaa gacgccgcat catcggtaac cgtaaacagc
    19321 ttcttctcgc tgagaaagca gagaaacaga aagaattaat ggagagaatc catgttggcg
    19381 acacagttga aggaacagtt aagaacgtta cagatttcgg tgcattcatc gatctgggcg
    19441 gagcagacgg acttcttcac atctccgaaa tgtcctgggg cagagtagag aacccgaaga
    19501 aagtattcac tgttggcgat aaagttaaag ttcttatcaa agagatcaac ggagagaaga
    19561 tcgcactttc ccttaaattc ccggaagcaa atccatggct cacagcagct gaggacttcg
    19621 ctgtaggaaa cgtagttaaa ggtaaagttg cacgtatgac agacttcggc gcattcgtag
    19681 agcttgcacc tggagtagat gcactccttc acgtatccca gatttccaga gagcacgttg
    19741 ccaaacctgc agatgtactg tcaatcggac aggaaatcga agctaaggtt gttgacttca
    19801 acggagaaga caagaagatc agcctgagca tgaaagctct tgaggcaccg gctgaggaag
    19861 ctgcagaaga ataataagag attactcata aaagaatact catgaatata cttgatttct
    19921 ataaaaagga aaatttgccg gagggttatg ttgatctacc cacagtggta aaaacaatat
    19981 ctgatatggt tcgtgaatta ccgttttggt gtgctatggt tgagttgatg aacaagatta
    20041 gttctgaaaa tgatagtaat attgtgactc aaaagtggaa agaacttctt ctaaaattgg
    20101 caaaaagtta tgtgaagata ctggagccgg acgcaaaaga aaagtgcatt gaaatattag
    20161 cgacacttca gtccaactaa tgtaaagcac ggtacactaa aaaaggaaag aggttattac
    20221 catgccaaga acgaaaggca gcaaaaaccg tcccaaaatc aataccacca acgactacgc
    20281 atcccaaata actgaaaagt aagaacaaat cacagcctta accaccgaga tcgtatctat
    20341 ccagaaagcg attgaagagc agaagaacac attgaaagag aagaagactg ctctgaagaa
    20401 ggccgaaaaa gaagtggcat ccctggaagc gaagaaggcg aaggcggatg ctaaggccgc
    20461 tgaagaagca aaaaaagcag aagccgagag tgtactgaag aagttgctgg caagcgggat
    20521 gagtgcggac gagattctgg aaaagctgaa ataaacaaga accaaaaaaa ataatgccgt
    20581 gtggacaaac tgaactccag gagttcacac ggtctttttt gaaggtagct gtatagttta
    20641 taacgaaaat aaagattgaa tagaaataaa agaaatggag cgtaagaaaa atgaatttat
    20701 caaaaataca ccacatcgca attatcgtat ctgactacga agctgcaaag gatttttatg
    20761 tgaacaaact ggggctctct gtcatcagag aaaactatcg cccggagcgc aaagactgga
    20821 agctggatct tcgtgttaat gaacacactg agctggagat tttcgctgag gaaaacccac
    20881 cgaagcgtgt gaaccgcccg gaagcctgcg gtctgcgtca tcttgctttc tgtgtagaga
    20941 gtgtggagca gacagtgaat gagctggcag aggtcgggat tgaatgtgag ccaatccgtg
    21001 tggatgatta cactggcaag aagatgactt tcttccatga cccagacgga ctgccgttgg
    21061 agctgcatga gtaaaatgaa gaaaacaaga aaaccaggcg gtggccggaa gaagctgaag
    21121 ccggagtatg atgccaggaa aaatctgaaa gagcagatgg aaagtgcagt ggcattttat
    21181 gaggaggaat gctccctcca agatatcgca gatgctctag ctctaaaccc cattaaagtg
    21241 aggaagctgc tcatcacggc aggtgtgtat gaatcagaag tggcggaaaa agtaaaaaac
    21301 acttttgaag aataccgtga aactcaggac tacaaaacct ccatactctc aaccgcaaat
    21361 gcgcttcaac tctccaaagc ctccgttacc tcgtacctac catatcagaa aggcgtgtat
    21421 tttccaagta ctgcatcaaa agagaaaatc agtgtaggag cagagcggca gcggagatat
    21481 agagcaatga agcggtggag ggatgagcca acagaagaaa acttctgggg tgtggttctg
    21541 gcctatgctg gagtaaaatt taagacctac tccgggttgc cattctctta cgaaataaaa
    21601 aaaggtagga acggcgagta cacgaaagag ctgtggatcg accgccggga gaagagtaag
    21661 agtttggcat ggagttctat atttttggca ctaggaaata taaaagaaga agtagtagag
    21721 agacccaaag ctctgggcga tatccgggga gtgacttaca tttatgggat gttctatcgg
    21781 tttggactga ttgatgtgcc ggatgaagtg aaggagaaga tgggacatcc gaaaacccgc
    21841 aaaaaatagg ttactatgta tagaagtgtg ccgtaactga ggatgtgaat ctcggttggg
    21901 aaggatggta gcattataga aaaactgaag gaaatgctgg aggagtattt gaagaaaaca
    21961 gagccggagt attacccgcc ggtagagaat ctgctggatc tgatctacga gcattacacg
    22021 gagaataatc cagtagagaa aaacacagtt gccgggaaaa ctgcaaaggc caaggaaaag
    22081 gagctggaag agtggctgag agggctggat ggaatggata ggctcgtaga tgactacgtc
    22141 ggagataaga ttccgctttg ggagaagatc atggatcggc agggaacggt gtgctgtgca
    22201 tgggagaaga ccgcttttga ggaaggcctg aaagtcggaa ttcggctcat gatggaagtg
    22261 tatagtttgt gacggaaata aagtgaactc ctggagttca aaaaaagccc tcgcttgttg
    22321 cggcgagggc gtgtgttctc atttttcagg tttttcagct tttttcttct tcggtgcaat
    22381 tttgtggcca gagtagattg ccatgcccat gcagaccaga gagccgcaag cgaaatactt
    22441 gtgagcctgc atcagctttt tgcagcctgt gtagaagcat cctgccatac aggcaagtgc
    22501 gccgagtgac caatatttat gtgctttcat tttgtgtgtt ctccttatct tctttccgta
    22561 ttctaagcaa ttctgctatt tcattgttac tcgctaagcg taccgctgac ttctctttat
    22621 aggtttgtgc tccgcagtca ggacaacgat caggtagttc ctcagtagag aagcagtagc
    22681 ggcaggcatc gcaaaagtag tagttcaagt tatatttcag tattcagatg aagaaataag
    22741 tcgttttgat gaaattatac attccatggc gcacttgatt atagagtttt cacaaggggg
    22801 aggatttgat aatacggata accagtacgg gtaattgctt gctttgtaat aataattccc
    22861 acattgcaaa tcataccctt cgcaatatta tgcgtatgat agaggccaga catgatgatg
    22921 tgatacaggc atggattcaa tattttggag aaatccgata tttttgttag aagataggat
    22981 aattgtcaga ggtctgccct ttgcacagaa aggtgtaaaa ggcagacctc aatatgaatg
    23041 attatttgct tacaatgtat cagaaaccag taagtctgaa taccattaat tcacttgcgg
    23101 attcatcttc tcgtttctgt gtcataagaa gcattgcaga accatcgtct gcgactttta
    23161 tatcttcaag ccaggggtat ctggttccga aaatatcgct gcattgtatt ttaccgagaa
    23221 gagttccgtc ttttgaccag aagtagagta ttctggcatt tccatctgtt gcaatatatc
    23281 cgtttgctgt ctctgctact ccagtgatgt agccaaaaga agcagaatca tcggatggat
    23341 cacgaccaag aagcaactgc tggtttccat cctgatcata tactgctatt ttatatgggg
    23401 catcatctcc gacaagacat ccgtatacca taatatgttc atttccgatc tcaatcagac
    23461 tgacttgttt aaaaataccg gttcgtactt cgtcatcatc cattgaggtt aagatccagg
    23521 gttctttgag tatgttgcca tcctggaatg ttattttctc cgtatcattg ctataggaat
    23581 aggccagtcc ccacgctccg gacggatgca tggtcaggtt gccgcttatg tcatgctttg
    23641 ctgtggtttg ttcatctttt atgacgattc ctttttttgc tgagagagaa acataaagtt
    23701 ttccattagt atctgcagat agatcatttc ctttctcatc cattatatca gaggacagaa
    23761 gattcaggaa gtttcctgta tattcataag tttccagagt gttatatagc tgatgataca
    23821 tccggtctcc ggacagtgca aatcggtgat acatgatctc aaatccggcc tgggaaacat
    23881 taaatggaat atactctgct tcaattgcga aaagcaatca gcagtgggtg gggacttgct
    23941 tgtatcagga ggagtgcaag ctccttctga taaa
//
