LOCUS       gnlProkkaGPMMGMEN_167  11361 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPMMGMEN_167.
ACCESSION   gnlProkkaGPMMGMEN_167
VERSION     gnlProkkaGPMMGMEN_167
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:09:53
            Original ID  :: gnl|Prokka|GPMMGMEN_167
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2423
            Orig. end    :: 13784
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11361
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11299]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11299
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..11361
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11361
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             457..702
                     /locus_tag="ctg167_4"
                     /transl_table=11
                     /translation="MEQIADFIKQLYEYYYLKKNEIKKLQKNISPELLASFGRQLTKTE
                     DTKVELHKAVLNLAKKVMPDKRKTQIYAHFLEKESV"
     CDS             complement(890..2185)
                     /locus_tag="ctg167_5"
                     /transl_table=11
                     /translation="MIYFETFSVPTADTLFLLILSILALESAHSIRFLYQHFLSGVTEK
                     SLNVFYYACSYAKVDYSRFMNTTARIALKLIPNSLQTQPVFLCVDDTMVSKFGTKFENV
                     SKLFDHAAHNGSNYLNGHCFVSVMLCVPVWNHDKVSYLSVPLGYRMWQKKESKLELAAS
                     MIRQVMPEFHGKEHVIILCDSWYTKQNLVSVIDEYPNLDLIGNARTDSVMYDLEPARTG
                     HRGRPAKHGKRLSVETDFTFSNEKIGDYYTGVRRVLTRIFGTREVLAYVTAAEKEHGTK
                     RLFFSTVFPEDLQIFCAWQEKAPLNQTGSDRMKYIPLFLYSFRWNIETSYYEQKTFWSF
                     CSYMVRSCKGMEMLVNLINISYCAMKILPYQNEHFSEYRTKSVQEFRFELSQGIRSQIF
                     FATFVKNIETHIKSNAMTRALKQLVCQQVYHL"
     CDS             2402..3067
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 209.1; E-value: 1.1e-63)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg167_6"
                     /transl_table=11
                     /translation="MHNILIVEDDKDIQETLEFFLKDNGYMTDKASNGIEAIDKFETNK
                     FDLILLDIMLPKVDGYAVCENIRKKSQIPIIIISALSSEENQIKGLDLQADDYIIKPFS
                     IPILLRKISAIFRRNKYNEEIGVLIYKNVKLDLDSYKAFVSDKEVMLTKREFEILHELI
                     LNQGKILTREILMERVWQYEYIGNARIVDNHIKNIRKKIGDEVIKTIRGVGYKVDKIY"
     CDS             3051..4460
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 132.3; E-value: 4.9e-40)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg167_7"
                     /transl_table=11
                     /translation="MIRYIKSHLSVQVFFLTLIMQISMGLITYNFIMIFTPQTYLDKIN
                     KNIDSVLNETIGQFSDMTMSQCKVKLLNLTKSYDIMINLTDEKGREIEFGSDMQYTADY
                     QDVRWKIRTNIEKKYTFKPKNESDTYYIYVLSDGERVNLYIDSLKEILPELIILILFIS
                     LVLSILYAKHVAVPVIRISELARKLADLNFVNYVDTGRKDELGRIEESLYELSERLSVA
                     LSELENANENLREEIEKERNMEKQQLSFFSSASHELKTPITALKGHLQGMLYDVGEYKE
                     HRKYLKRCLDIIENMQKLETEIMSSAKIRSSGFKMNISKFDLRMLVIEVINEYEDVAMH
                     RGITIQDELGDEVAYIKADYDLLKRAVSNIISNAIRYSPENGNIKITIDDNEKAERLSV
                     INQGSQIPENQIQKMFLPFARLEESRNKETGGSGVGLYLVKMILDLHKFSYCLRNKEAN
                     SIEFEILFFYK"
     CDS             complement(4702..5214)
                     /locus_tag="ctg167_8"
                     /transl_table=11
                     /translation="MSRIGILYKIEEMIHNKTPEEKYEERQKQSRPVMDALFEWLHTME
                     DSVDRSSLIGDAILYTLNQEVYLRRYLEDGHLSIDNNSAERALKNFAVGRRNWLFAKSV
                     RGADASALVYSITETALLNNLKPYAYLTYILDELRKMGAFPKEEELKKLLPWSEYLPEY
                     CRTKLKK"
     CDS             complement(5189..6349)
                     /locus_tag="ctg167_9"
                     /transl_table=11
                     /translation="MEPIFTDKQLNNMSREDLISLMKIVQEQTKKKDTEIQLLKEKQKE
                     LEFLNAMLSDRLTLAQRKQFGASSEKYAEGYEQMNLFNEAEASADAETEELFEEIRPSS
                     YKRKKRKGKKEEDLSNFETVETRTYKLEGEARYCPECGKKYNVVTKEIVKRLRFVPAKF
                     AVEEEITYVYSCPKCGSMKRPEKEPSLIRGSIATPSLVAGIMNAKYVNGMPLARQEREF
                     ARYDLDLSTKTMANWIINCADRYLKPLYQLMKEELLESRYIHCDESRIQVLGEPDQEGT
                     TQNWMWVYLTDESSGSPQMVLFDYERTRAGYHPVNFLGNRFRGYLTCDGYQAYHSLGEG
                     IIVSGCLTHARRRFDAALTALKKRLHKRTAERDRCISGDVKDRDPL"
     CDS             complement(6848..7189)
                     /locus_tag="ctg167_10"
                     /transl_table=11
                     /translation="MNKEEKAKLWSDRIQQYQTSGQTCKQWCTENGIPLSTMGYWIRRF
                     AKEEPASESEQDMVFVRLPSEQEAARKLLSEESSSVRIFISDSIRIEISDSCRMELMES
                     ILGFLQRHA"
     CDS             complement(7263..7481)
                     /locus_tag="ctg167_11"
                     /transl_table=11
                     /translation="MPVHSKKHYNRPFKLKVLLSYLSGESNHSEFTGSFKISSFKTMQK
                     WDFQNNDCRNIKSSKTEGTVLITKVSR"
     CDS             7635..8912
                     /gene_functions="other (smcogs) SMCOG1229:transposase
                     (Score: 276.7; E-value: 4.2e-84)"
                     /gene_kind="other"
                     /locus_tag="ctg167_12"
                     /transl_table=11
                     /translation="MPNTVKVLKLTTDEKSSLECLLRCPTTEARKYIRAKILLLKSDSY
                     TNEAIADKLDITVPTVRLCLQKYFAGGIDNALNDCKGKGRKQEISDDDITWVVNKACQK
                     PLDYGFSAEFWYPASFTRFIQSIAVKEEHPRLEHVSEFSLRKILANAKIRPFKVTYYCE
                     RRDPDFDSKMHNVLVIYKQVSLQFDKDGNLLPFEGTPVHTLSYDEKPGIQAIGSTTPDL
                     PPISNTEKGSSYMRDYEYIRYGTISLLAAIDLLTGEAIPLVSDTHKSSDFVEFLTRLDA
                     KYPEVDKIRLILDNHSAHTSQETQRYLNNHLGRFEFVFTPTHGSWLNLVEGFFSKLTKQ
                     MLQGIRVASKEELSERIYKYFDEINQIPIPYHWSYNLDSIDLATEDIDQIVYKVVNAKA
                     ASEELSCKRAPKPIKRSPKKSAKTEN"
     CDS             10001..11299
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg167_13"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     8.6e-14, bitscore: 41.5, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 7.4e-09,
                     bitscore: 25.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 4.4e-14, bitscore: 43.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.1e-10, bitscore: 30.3,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDMKRLYNAIPVKNYKSLGTVFETTSGLYVYDTGTGKVFSCNEV
                     TYNLFKIIFSGGDTNEIYEKYSAQEINKSISEIIEMIQKENILQASYSEFDRETDFELE
                     AIYNYSLQSLILEVTQKCNFRCKYCIYHSFNEYYRNYGLQDMNWETAKKAIDYVSRHSG
                     EKELSIAFYGGEPLINYDVMKKTIEYSEMVMPKKTLIFAFTTNLSLMTLEKAKFFAKHN
                     CYIMCSLDGPKIIHDAYRVDIKGDGTFNKVIEGLKNLLIAFGDRAKTHIKFNVVICPPY
                     SRKKLDAIKEFFDKLDYLPAGIDIKYSYVESGSLRKEDIDYTYFPEGEDIIGDVPPIDI
                     WLTEELPKQSSDQNVIFTLARDALARVHKRFLLDHPCEKMKRNGCCIPGGRRIYVDIKG
                     NIALCERVGKSPSLGNINKGIDLEQVKRYVSAP"
ORIGIN
        1 taaaaaagag ttttccgagg cttccgatta taataacagc cgatggattg tatgtcagcc
       61 agaaggttat acaaacctgt acggataatg gctgggatta tatcatccgt tataaagaag
      121 gatgtgcacc atccatagca caggaatatc aagaactgcc tgaaaaagaa aagataggtt
      181 cagaaataga ataccagaat cagattatgt ttcagaatac agatgtaaat ctgatatatt
      241 atacagaaaa gaaaattcag gcagatgggg aagaaaaaat aacaaaattt gcatggatta
      301 caaatatcac aattaccaaa agcaatgcaa agaaaattgt gaaagccgga aggaacagat
      361 ggaaaataga aaacatttaa ccgccagaag cattggcagg gaaatataga gcatgcatgc
      421 agttggaatg aacaggcaca aaagaaccat tatctgatgg agcagatagc agatttcata
      481 aagcagcttt atgaatatta ttacctgaag aaaaatgaaa taaaaaaact gcaaaaaaat
      541 atatctcctg aattgttagc cagctttgga cgtcaactaa caaaaacaga agatacaaaa
      601 gtggagttgc ataaagcagt tctaaactta gcaaagaagg tgatgcctga caagaggaaa
      661 acacaaattt atgcacattt tttagagaag gaatccgtat aatcattcaa tgtgaataac
      721 ttttctaaat ttataagaaa atgtgtaaat atgtggattt acaaaattgg caggctataa
      781 aataaattta cctttcgaag ctggtatcca agggaaaatc ttgacaagcc gtaaaaatgt
      841 aatataatta ttttatagag attaatagtg aatacaccag tttacaactt tataaatggt
      901 agacttgctg acaaaccaac tgttttaaag cccttgtcat agcatttgat tttatgtgtg
      961 tttcgatatt tttcacgaaa gtggcaaaaa atatctgact gcgaataccc tgacttaatt
     1021 caaaacgaaa ctcctgtaca ctcttggtgc ggtactcaga aaaatgctcg ttctgataag
     1081 gcagaatctt catagcacag taactgatgt taatcaggtt aaccagcatc tccatccctt
     1141 tgcagcttcg caccatatag ctgcaaaaag accagaatgt tttctgctca tagtagctcg
     1201 tttcaatatt ccagcgaaac gagtatagaa agagtggaat gtatttcatc cggtcactgc
     1261 ctgtctggtt cagtggtgct ttctcctgcc atgcacagaa aatctgcaga tcttctggaa
     1321 aaacagtgct gaagaacagc cgttttgtgc catgctcttt ttcagcggca gtgacatacg
     1381 caaggacttc acgggtacca aagatcctgg tcagaacccg gcggacaccg gtataataat
     1441 ctccaatctt ttcattggaa aaagtaaaat ctgtctcaac agaaaggcgt ttgccatgtt
     1501 tagcaggacg tcccctgtgt ccagtgcgcg caggctcaag atcatacatg acagagtcag
     1561 tccttgcatt accaatcaga tccaggtttg gatattcatc aatgacagat accaggttct
     1621 gttttgtata ccagctgtcg caaagaataa tgacatgttc tttgccgtga aattctggca
     1681 taacctgccg gatcatggat gcggccaatt ccagttttga ttcttttttc tgccacatac
     1741 gataaccgag aggaacagaa aggtacgata ccttatcgtg attccagacg ggcacgcaga
     1801 gcatgacgct cacaaagcaa tgtccattca aatagttgga accattgtgt gcagcatggt
     1861 caaacagttt tgaaacgttt tcaaactttg tgccaaattt agataccatt gtatcatcaa
     1921 cacacagaaa taccggctgc gtctgtaatg aattcggtat cagcttcaaa gcaatccggg
     1981 cagtggtatt cataaatctg gaataatcaa cttttgcata ggaacatgca taataaaata
     2041 cattcagtga tttttctgtt accccggata aaaaatgctg ataaagaaaa cggatggaat
     2101 gcgcggattc caaagccagt atggataata tcaacagaaa cagggtatct gctgttggaa
     2161 cagaaaaagt ttcaaaataa atcaaaaaat attgatgaag tctaccaatc agtgtttttt
     2221 cgttgtataa tgtttttgtc gtacagggtc actttccttt gtaatgtttt ttgccaaatt
     2281 cattatacat cagaaagtcc tgtacgatat ttttttatga aaaagttgta aagtggtgta
     2341 gtgaatagtc attttattat ttgttactaa tgtttctatg aattagaaag aggaataact
     2401 tatgcataat attttaattg ttgaagatga taaagatata caagaaacat tagagttttt
     2461 tttgaaagat aatggatata tgacagacaa agcaagtaat ggaattgaag caatagataa
     2521 atttgagacg aataaatttg atcttatatt attagatata atgctgccta aagttgatgg
     2581 ttatgctgtc tgtgagaata ttagaaaaaa atctcagatt cccataatta ttataagtgc
     2641 actttcaagt gaagaaaacc aaataaaagg attagattta caagcggatg attatattat
     2701 taagcctttt tcaataccga ttttgctacg taaaataagt gcaattttca gaagaaataa
     2761 atataatgag gaaataggtg ttttgattta taaaaatgtc aagttggatt tggatagcta
     2821 taaggcattt gttagtgata aagaagttat gttgacgaaa agagaatttg aaattttaca
     2881 tgaacttatt ttgaatcaag ggaaaatatt aactagagaa atattaatgg aacgcgtatg
     2941 gcagtatgaa tatataggta atgcaaggat tgtagataat catataaaaa atattaggaa
     3001 aaaaataggt gatgaagtaa ttaagactat tagaggagta gggtataagg ttgataagat
     3061 atattaaatc tcatttaagc gtacaggtct tttttcttac actaattatg caaattagta
     3121 tggggctgat tacctataat tttattatga tttttacacc tcagacatac ttagataaaa
     3181 taaataaaaa tatagattct gttttaaatg agacgatcgg tcagttttct gatatgacaa
     3241 tgagtcagtg taaggttaaa ttgttaaatt tgacaaaaag ttatgatatt atgataaatt
     3301 taacagatga gaaagggaga gaaattgaat ttggaagtga tatgcagtat acagcagatt
     3361 atcaagacgt tagatggaaa ataagaacaa atatagagaa aaaatatacg tttaaaccta
     3421 aaaatgaaag tgacacatat tatatatatg tactttcgga tggtgaaaga gtaaatctct
     3481 atatagactc attaaaagaa atattgccag agcttatcat tttaatacta tttatttctt
     3541 tggtgttgtc aatattatac gcgaaacatg tagcggttcc ggtgataaga atttcagagc
     3601 tggctagaaa actagcagat cttaactttg ttaattatgt tgatacgggt cggaaagacg
     3661 aattgggaag aatagaagaa agtttgtatg agctatcaga acgtttaagc gttgcgctta
     3721 gtgaattaga aaatgcaaac gaaaatttgc gagaagaaat tgaaaaagag aggaatatgg
     3781 aaaaacagca actttcgttt ttttcatcag cctcacatga gttaaaaaca ccgattactg
     3841 cattaaaagg acatttacaa ggaatgttat atgatgtggg agaatataag gaacatcgta
     3901 agtatttaaa acgatgtctg gatattattg aaaatatgca aaagttagaa acagaaataa
     3961 tgtcgtcagc aaaaatcaga tcttctggat tcaagatgaa tatttcaaaa tttgacctaa
     4021 ggatgttggt aatagaagtt attaatgaat atgaagatgt tgctatgcat agggggataa
     4081 ctatccaaga tgaattggga gatgaagttg catatattaa agcagattat gatttgttga
     4141 aaagagccgt tagtaatatt attagtaatg caatacgcta ttctcctgaa aatggaaata
     4201 tcaaaataac gatagacgac aatgaaaaag cagagcgttt aagtgttatt aatcagggaa
     4261 gtcaaatacc agaaaatcaa atacagaaaa tgtttttacc atttgctaga ctggaagaat
     4321 cgcgaaataa agagactggt ggtagtgggg tgggattata tttagtaaag atgattcttg
     4381 atttacataa gttctcttat tgcttgcgta ataaagaagc aaatagcata gaatttgaaa
     4441 tattattttt ttataaatag gaatttattg ttattttcta taatatattg cagtgcacag
     4501 taatgattta gtaaagttta gtaagtaggt aatcatccgt atattgacat tttataaaag
     4561 ccatctgata ttgttcctgg ctgtctgcca gattctatat cagatgtaag taggtaatca
     4621 ttcgtatatt gacatcttat aaaagccatc tgatactgtt cctggctgga tttgccagtt
     4681 cctatatcag atggcttagt attatttttt tagtttagtc cggcagtatt ccggaagata
     4741 ctctgaccat ggaagcagtt tctttaattc ttcctcttta ggaaaagctc ccatttttct
     4801 gagttcatcc aatatatagg tcagatatgc gtatggtttc agattgttca gaagtgccgt
     4861 ttctgtaatg ctgtaaacaa gggcgctggc atcagctccc cgtacacttt tggcaaacag
     4921 ccagttgcgg cgtcccactg caaagttctt caatgcgcgt tctgcactgt tgttatctat
     4981 gctgagatga ccatcttcca gataacgcct cagatatact tcctgattaa gcgtatacaa
     5041 aatggcatca ccaataaggg aagacctgtc tacagaatct tccatcgtat gcagccattc
     5101 aaacagggca tccataaccg gacgggactg tttctggcgc tcctcatatt tttcttccgg
     5161 tgttttattg tggatcatct cctcgatctt atagaggatc ccgatccttg acatcgcctg
     5221 atatgcaacg gtctctttca gctgttcttt tgtgaagtct tttttttaat gctgtgaggg
     5281 ctgcatcaaa acgtcgtctt gcatgggtaa ggcacccgct tactatgata ccttctccta
     5341 aactgtgata agcctgatat ccatcacagg tcagataccc acgaaacctg ttccctaaaa
     5401 agtttacagg atgatatccc gcacgggtcc tttcataatc gaagagtacc atctgcgggg
     5461 aaccactgga ttcatccgtg agatataccc acatccagtt ctgggtcgtc ccttcctgat
     5521 ccggttctcc gagtacctgg atacggcttt cgtcacaatg gatatatctg ctttccagaa
     5581 gttcttcttt catcagctga tacagcggtt tcaggtatct gtctgcacag tttatgatcc
     5641 agttcgccat agtctttgtg gagagatcga gatcatatct ggcaaactct ctttcctgac
     5701 gtgccagagg cattccattt acatatttag cattcatgat accggcgaca agggaaggcg
     5761 tagcgatact tccacggatc agggaaggtt ctttttccgg acgtttcatg gacccgcatt
     5821 tcgggcagct gtatacataa gtgatctctt cttcaaccgc aaactttgca ggtacaaagc
     5881 gcaggcgttt tacgatctcc tttgttacta cattgtattt ttttccgcat tccggacagt
     5941 aacgggcttc cccttccagt ttataggtcc tggtctcaac ggtctcaaaa ttggaaaggt
     6001 cttcttcctt ctttcctttt ctttttttac gtttataaga ggatggccgg atctcttcaa
     6061 aaagttcttc tgtttctgca tccgcactgg cttctgcctc attgaacagg ttcatctgtt
     6121 catagccttc ggcatatttt tcactggatg caccaaactg tttcctctgt gcaagggtaa
     6181 ggcggtcaga gagcatggca tttaagaatt caagttcttt ctgcttttct ttcagcagct
     6241 ggatctcggt atcttttttc tttgtctgct cctgcacgat cttcatcaat gagatcagat
     6301 cttcccggct catgttattc agttgtttat ctgtaaagat cggttccata tcctgttctc
     6361 cctgctttag cgttattaaa agtatatcat ggttccagct gttttcctat aaaaaactgc
     6421 gcttacggat ataggaaata cgctgggaaa tgccatgttt ttcatgattt ttacgggatt
     6481 gacagctccg ctgtcttatg cttacaggat gatctttgga tggtgttcct caaatgcatc
     6541 cctgggattt aaggagagcc cgtcacacag ccagtggatc tctttcagag tcacctgacg
     6601 gagttcgtcc ggagtatccg gccagtggaa ggcattacgg tcgagccgtt tcatcaggat
     6661 ccagaatccg gatccgtccc attgaaggat ttttatagaa gtacgccgac ggttgcagaa
     6721 cgcaaacatg cagcgtgagt atgggtcgag gtgaaatttt aatttgatga tagccgccag
     6781 accattgtaa ctttttctta gatcagtgac accacaggag agatataccg ttgtccctcc
     6841 tgccaggtca agcatggcgc tgcaggaatc ccagtataga ttccatcagt tccattctgc
     6901 aggaatcaga tatttcaata cggatactgt ctgaaataaa aatacgcacc gatgaagatt
     6961 cctcagagag cagctttctg gcagcttcct gttcagatgg aagtctgaca aagaccatat
     7021 cctgttcaga ctcggatgcc ggctcttctt ttgcaaatct gcggatccag tatcccatcg
     7081 tagataaagg gataccgttt tctgtacacc attgtttaca tgtttgtcca ctggtctggt
     7141 attgttggat acggtcagac cagagttttg ctttttcttc tttattcata gtgatataga
     7201 atacctcctg agtttcaagg agattgtagc agaataaaaa acgaaaaaac agatacggat
     7261 gattacctac ttacttttgt tatgagcaca gttccttctg ttttagaact ttttatattc
     7321 ctacaatcgt tattctgaaa atcccatttt tgcatagttt taaaagacga tattttgaaa
     7381 ctgccagtaa actcagaatg gttgctttct ccagaaagat atgacagtaa aactttcagt
     7441 ttgaatggtc tgttgtaatg ttttttagag tgaacaggca tcagtgcagt atcctcaccc
     7501 gctttgtaac ttgtaattca tttgcgaata ctggtagtga ttacactata ttctagtcct
     7561 agtataatcc attttaattg tctttatgtt tgaagtatgg tatactattc ccataatgaa
     7621 aggggaatga tacgatgcca aatacagtaa aagtgctgaa gcttacaacg gatgaaaaaa
     7681 gctctttaga gtgtcttctt cgatgtccaa caacggaagc cagaaaatat atccgggcaa
     7741 agattttgtt attaaaaagt gattcttata ccaatgaagc cattgccgac aagcttgata
     7801 taaccgtgcc taccgtccgc ttatgtctcc agaaatattt tgctggcggt attgataatg
     7861 ctttaaacga ttgcaaagga aaaggtcgca agcaggaaat atccgatgat gacatcacat
     7921 gggtggtcaa taaagcctgc cagaagccgc tggattacgg tttttctgct gaattttggt
     7981 atcccgccag ctttactcgt tttatacagt ctattgctgt gaaggaagag catccaaggt
     8041 tagaacatgt ttcagaattt tctctcagga aaattcttgc caatgccaaa atccgtcctt
     8101 ttaaagtcac atattactgc gaaagaaggg atcctgattt cgattcaaag atgcacaatg
     8161 tccttgtaat ttataagcag gtttcactgc agtttgataa agacgggaat ctgctacctt
     8221 ttgagggaac ccctgtccat acgttatcct atgacgagaa accgggaata caagcaatcg
     8281 gctccacaac tccagatctg ccgccgatta gtaatacaga gaaaggcagc agctatatgc
     8341 gggattatga gtatatccgc tatggtacta tatcgttact ggcggcgata gatcttctta
     8401 caggagaggc aatcccactg gtgagtgata cccacaaaag ttcagatttt gtggagttcc
     8461 tgacacggtt ggatgcaaaa tatcctgaag ttgataaaat acgtctcatc cttgacaacc
     8521 attcggcaca tacatcgcag gaaacacagc gatatttaaa taaccattta ggaaggtttg
     8581 agtttgtatt cacaccaact catggttcct ggcttaactt ggtagaaggt tttttcagca
     8641 aactcacaaa gcaaatgctt caaggtatac gtgttgccag caaggaagaa ctgtcggagc
     8701 ggatttataa atactttgat gagattaatc agattcctat tccataccat tggtcttata
     8761 atctcgatag tatcgacctg gctacagagg atattgacca gattgtgtat aaagttgtca
     8821 atgccaaggc ggcatcggaa gaactgagtt gtaaacgtgc acctaagcct ataaaacgaa
     8881 gtcctaaaaa gtctgccaaa acagaaaact aattaaaacg gattatacta gttctcgtag
     8941 agttgtttcc ttctccagat aatcataaac ggcttggtat ttttcaacga aagataagga
     9001 tgatggtaat ggacgttttt gaaatgcagt accttttttc aataggatat tggaagaact
     9061 agctttaaaa aatgaataaa cgaaaagagc tggatagtta ttctttaggc attgtagtga
     9121 acacagtcag ttttttttga ttaaattagt gtataaatgt atcaagaaat aaaaagcgaa
     9181 atttgtctgc tataataata ccaagaaagg agcttcttgt ataattcaaa tataaggaat
     9241 tccgagaaag aaggttgaaa aaaactcaga gtaaaataag attactgact ttgagcggtt
     9301 agtaaaaatc ttattaaaca gtgaggtact tgaaatgaat tataacacat agaacgtaaa
     9361 aattgtatat attgtggaaa ttactttttt aattcagcaa actttaattg atgggattga
     9421 tgtgggaagt ggaactcatt atgcaagggc tttttgttgg tgtaattatg agtactcaaa
     9481 gaagctgttt gcattcagca acgatgaagt tggagcgctt catttaaagg ctagatggac
     9541 gatacagctg agaaatcatg ataactggaa gtaacaagca aatatattgt aacagaaaaa
     9601 tgctcaccag aaagtactgt tacaggaaag aggtcagtaa tacaataaaa aagaatgagc
     9661 cgatagttgg caggaatatt ttccatgggc aaagaccctg taaagaagct gagctgacac
     9721 cctggttatg gaaaagagga aggagagaag ataggattca gcaatagtct gataatgcta
     9781 gtagacatgg gagtttgttg ccgtagatgg atggggatac actaagttat gtagaacgaa
     9841 aaaagaagac attttacttc gcccccaatt cactactttc gtaccagata cagagaaatg
     9901 tccattccta tggttccttt ttctgagata ttgattgatg aaacattaaa aatccttgat
     9961 tttaaagaaa aaaagacttg actatatagg gagaaaaaag atgggtgata tgaagagact
    10021 atataatgca attccagtga aaaactataa aagcttaggg acagtcttcg aaacgactag
    10081 tggattatat gtatatgata ctgggacagg aaaagttttt agttgcaatg aagttactta
    10141 caatttgttt aaaataattt tttctggagg cgatacaaac gaaatatatg aaaagtattc
    10201 agctcaggaa atcaacaaat caatatctga aataattgaa atgatacaaa aggaaaatat
    10261 actacaagca tcgtactcag aatttgatcg agaaacagat tttgaactgg aagcaatcta
    10321 taattactca ttacaaagtc ttatccttga agttacacaa aagtgtaatt ttagatgtaa
    10381 gtactgtata tatcatagtt ttaatgagta ttatagaaat tatggcttac aggatatgaa
    10441 ctgggaaaca gcaaaaaaag caatagatta tgtaagtaga cattcgggtg aaaaagaatt
    10501 atcaatcgct ttttacggag gagagccgtt aataaattat gatgtgatga aaaaaactat
    10561 tgaatatagt gagatggtta tgccgaaaaa aactttgatc tttgcattta caacaaattt
    10621 atcattaatg accttagaaa aagcaaaatt ctttgctaaa cataattgct atataatgtg
    10681 tagtttagat ggtcctaaaa ttatacatga tgcttatagg gtggatataa aaggtgatgg
    10741 aacattcaat aaagtgattg aggggttaaa aaatcttctt attgcattcg gagatcgtgc
    10801 taaaacccat ataaaattta atgttgtcat atgcccaccc tattcgagaa aaaaattgga
    10861 tgcaataaaa gagttttttg ataagttaga ctacttgcct gcaggaattg acataaaata
    10921 ttcgtatgtt gagagtggaa gtttacgtaa agaagatatt gattatacat atttccctga
    10981 aggggaagat attatagggg atgtaccacc tatagatata tggcttacgg aagaacttcc
    11041 aaaacaatca tcagatcaaa atgttatttt tacacttgca cgagatgcat tggcacgtgt
    11101 acataaaaga tttctgttgg atcatccttg tgagaaaatg aaaagaaatg gttgttgcat
    11161 acctggtggc cgtcgtattt atgttgatat aaaaggaaat attgcgttat gcgagcgggt
    11221 tggtaaatct ccttctttag gaaatattaa taaaggaata gatttggaac aagtaaaaag
    11281 atacgtaagc gcaccatagt gcatatatag acattattat agtaatttga gataattacc
    11341 tcaacaatta atacttgtca a
//
