LOCUS       c00157_gnlPro..        15805 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPMMGMEN_157.
ACCESSION   c00157_gnlPro..
VERSION     c00157_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 01:01:36
            Original ID  :: gnl|Prokka|GPMMGMEN_157
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15805
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1143
                     /locus_tag="ctg157_1"
                     /transl_table=11
                     /translation="TKKNHACFDFDIRFPKMPSYLRRSAIQHALGTVSSYKTRLDLWEK
                     IDGKSGKPKLVYENHAMPVFYRDVMYREGAEGKDEAYLKLYDGHDWKWSCVRLDHTDME
                     YLRKCWSGKKASAPTLEKRHQKYFLRFSYKEEVTLTKTPVKEQIICSVDLGINTDAVCT
                     IMRADGTVLGRRFIDHPSEKDRMYRTLGRIRRFQREHGSAQTQGRWAYTKRLNTELGKK
                     TAGAIVRYAEENHADVIVFEYLEMQGKISGKKKQKLHLWRKRDIQKCCEHQAHRKGMRV
                     SRICAWNTSRLAYDGSGTVTRDRENYSLCTFQTGKRYNCDLSASYNIGARYFIRELLKP
                     LPATERSLLEAKVPPVKRRTSCVYADLRELHLQMEILKVA"
     protocluster    1..15805
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6256:8508]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      6257..8508
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15805
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15805
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             2402..2761
                     /locus_tag="ctg157_2"
                     /transl_table=11
                     /translation="MPKTSYICNCDVIHEDIVNDVKSKMQPKDDYIQLASLFKLFGDGT
                     RVQILHALEQSEMCVCDLAVLLGVTKSAISHQLKALRLANLVKFRKEAQIVYYSLADDH
                     VKEIIDKGFEHLWQK"
     CDS             2821..5175
                     /locus_tag="ctg157_3"
                     /transl_table=11
                     /translation="MKRIFLLKGLDCPNCSAKIEKEVGELDGVQSSVVNLMKQTITVNV
                     TQTAADTIASQIETIVYSHEPDVEVQEETVMNVTKSYSLKGLDCPNCSAKIEKEVGELD
                     GVQSSVVNLMKQTLTINVAQTAADTIASQIETIVHSHEPDVEVSEIVQESYIPEKKQEA
                     NESYNNEDKKLTVRLATGAAIYAIGMALTVFAKVPLPIELAFLIVSYVILGGDIVWQAV
                     RNISKGRVFDEHFLMSVSTIGAFVIGEYPEAVAVMLFYQVGEFFQSLAVKRSRKSISDL
                     MDIRPDSATVRRNGELITISPENVSIGEIIIVKPGEKIPLDGVVLDGDSMLDTRALTGE
                     SVPRSVHKGDEALSGCMNQTGVLMIKTTKAFGESTASKIIDLVENASSRKAPTENFITT
                     FARYYTPVVVILAAFLAILPPIILGGGWTEWIRRGFVFLVVSCPCALVISIPLTFFGGI
                     GAASKRGVLVKGSNYLEALNNVSVIVFDKTGTLTKGVFNVTDILPANGFSKEQVLEYAA
                     EAESFSNHPIAKSILAAYEKEIDQSVISDYKEISGYGISVMAGEKKVFAGNTKLMDTEC
                     IEYTTCEKAGTKVYLAVDGQYAGCILITDEVKPDSKKAISDLKHIGVEKTVMLTGDDEK
                     IGKSVAEELQLDKYYAQLLPDQKVEKVELLDSKKRPGSKLAFVGDGINDAPVLARADVG
                     IAMGGLGSDAAIEAADVVLMTDEPSKLVDAIEVAKATKQIVMQNIVIALGIKSVFLILG
                     ALGIAGMWEAVFGDVGVTIIAVLNAMRILKK"
     CDS             5192..5710
                     /locus_tag="ctg157_4"
                     /transl_table=11
                     /translation="VKRKLILLVVTIVFLVGFGVILHSPPSMIDAVTGATPKSKKAAQA
                     SAQLEGSYVLGINMMSDGLDNENTRNKLKELALDDSETNETDLMKTDISFRLYVSETDY
                     PLVSYAKKLCDRLKQAGFSVDLKEYSNTMMLSRVVSGKYDVFLASDDFIDVTTLTQMDY
                     MIMDSEEMR"
     CDS             5721..6260
                     /locus_tag="ctg157_5"
                     /transl_table=11
                     /translation="MRKWNTILSVLMLLIFMIHGIMGSFMLNGVGSSAGKLLAWIGVGI
                     LVVHTVIGVILTVQSLQTAKQSGKMYLKQNAIFWARRASGLAILILLFFHIGLFGKVQN
                     GTYILFPFTTVKMVTQLLFVAAIFVHIFINIRPLLVSLGIISYKERRGDIYLILSVLLL
                     FIAGAVIFYYIGWQYL"
     CDS             6257..7801
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 270.5; E-value:
                     9.3e-83)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_6"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.6e-83, bitscore:
                     270.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.7e-17,
                     bitscore: 52.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTIIIIGAGLAGLSAALQAAENGCNVKLVSSLPSERAQSVMAE
                     GGINAALNTKDENDSPEEHFTDTIKAACGLADPNAVWGMTQAAPELVHWLLKLGVKFNM
                     SGYDDVDLRNFGGQKKKRTAFAQSDTGKQIMTAMIDAVRRKEASGMVERFSHHSFLTLR
                     LCGNICCGCVIRDEYSQETVELPGDAVIVATGGMHGLFGNTTGSLSNTGEVTAELFRLG
                     VPLANSEMIQYHPTTVKCGGKRMLISEAARGEGGRLFAMKDGKQWYFMEEKYPELGNLM
                     PRDITAREIWKVSHESEVFLDMTEISEEIISNKLSGLADDCMTYLHKDIRKEPVSVLPG
                     IHYFMGGILVDEQHRTPIQNLYAAGECCAQYHGANRLGGNSLLGALYGGRVAAKSAREQ
                     ADVVDLSCATQIDFPPTSQISEIKQLNKVMQDTMGVVRNENTLLNGIQTVQALTGNLPL
                     LGMAVLKSALARKESRGAHWREDYPKSNDDDYLKTTVARFDGKQIQISFVPVPERR"
     CDS             7807..8508
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 91.5; E-value: 1.1e-28)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg157_7"
                     /sec_met_domain="Fer2_3 (E-value: 3.1e-29, bitscore: 91.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00071, bitscore: 10.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LVYKIRIRRQESQKSDSYWQEFEFDGSKNSSVANVLKELNSRTPL
                     KDNSGNIVTPISWECSCMVRKCGACAMLINERPRLACSTFLHTLKGSTITLEPLSKFPL
                     VRDLIVDRSILFENLKKLNLWLESEAYMNRWTHEPRYQSARCLMCGCCLEVCPNFSANG
                     TFAGAVAAVNAFRILNEEQESTHLNEISAEYKKKYFEGCGKSLSCHDICPIGLPVEELL
                     VRSNAAAVWGK"
     CDS             8533..9276
                     /locus_tag="ctg157_8"
                     /transl_table=11
                     /translation="MYEENQKLKTWITPDLATEYLAGAVLLGAAPCTAMVFVWSTLTKG
                     NPAYTVVQVASNDIIILFAFVPIVKFLLGVSNVSVPFQTLFMSVVLFVVIPLAAGIITR
                     LLVVRKKGTEYFEQTFLHKFDSATTVGLLLTLILIFMFQGEVVLDNPLHIILIAVPLII
                     QTFFIFFLAFGVCRIIRLPYDIAAPAGMIGASNFFELAVAVAVALFGTSSPAALATTVG
                     VLTEVPVMLTLVKIANKLKEKFKYE"
     CDS             9269..9682
                     /locus_tag="ctg157_9"
                     /transl_table=11
                     /translation="MNKKKVAFICVHNSCRSQIAEALGKHLASDVFESYSAGTETKLQI
                     NQDAVRIMKELYGIDMEAEGQYSKLIDEIPVPDIAISMGCNVGCPFIERPFDDNWGLED
                     PTGKSDEEFKKVIDEIRMQIFILKQRLDEFEEN"
     CDS             9916..10308
                     /locus_tag="ctg157_10"
                     /transl_table=11
                     /translation="VYYSIVILTILYYLRVADLMGITSPYPRENIIAGNYILADTQAFL
                     SKCHRQQNKEILIRHSPRIGECFLLSNIQLTEKIKKISSGGCKNASQRFVLMKGYLGGK
                     NKKLSSRACIYALHLLNICKDIFEPT"
     CDS             10388..10609
                     /locus_tag="ctg157_11"
                     /transl_table=11
                     /translation="MLQYFQFPKFLLKLRISQTAKFLYMILYDRARISRKNSWIDKYGN
                     VAPSKVTEKYKSNKYHEVNYCYGEGESL"
     CDS             10609..11424
                     /locus_tag="ctg157_12"
                     /transl_table=11
                     /translation="MREEDTVCVGSDGLKYCKVCGEAKEAFFPKGGFMGMKKHSRQCAC
                     DRKVYEEEQKYFKDKEHRELVSRNTSICFDESRMEEWTFENADMSDTVMHRAKKYVDNW
                     EEMKRNHIGCLFWGPVGTGKSFIAGCIANELLKQEVMVKMTNFNTIIDDIFPLADKTEY
                     INALASYQLLIIDDLGVERNSEYALGIIFSVIDRRIRSGRPLIITTNLPLKEIKNETML
                     DKRRIYDRILEMCTPMYVGGTSKREVIASMKMEKAKTLLNTNRGEEDCE"
     CDS             11421..11630
                     /locus_tag="ctg157_13"
                     /transl_table=11
                     /translation="MNHTEKTIPVWEKYSLNVSEAAEYYRIGEKRLRQIAGENEGADFI
                     LEVGSHIRFKRKLFEDYLDTASTV"
     CDS             11766..12965
                     /locus_tag="ctg157_14"
                     /transl_table=11
                     /translation="MSEKRRDHRGRILHNGEIQLSDGRYRFKYVDEMGKERCVYSWRLD
                     HNDATPKGKRRTLSLREMEKKIEADHFEQIATNGGNMTVLELVEKYTSTKTGVRPTTVA
                     GYGTVINLLKKDPFGKRRIDTVRISDAKCWLIHLQQVEKKSYSSIHSIRGVLRPAFQLA
                     VDDDLIRKNSFQFQLMEVVVNDSVTREAISRAEERKFLRFVKEDPHFCRYYEGIYILFK
                     TGLRISEFCGLTISDIDFKEHTINIDHQLQKKSKIGYYIQETKTTSGTRKIPMTADVEE
                     CFRKIIEKRNPPKAEPMVDGKSGFLYFDKNESICYSLHWEHYFQHIIQKYNNTYKVQMP
                     VITPHVCRHTYCSNMAKSGMNPKALQYLMGHSDISVTLNTYTHVNLEDAREEVARIQVV
                     "
     CDS             13330..13707
                     /locus_tag="ctg157_15"
                     /transl_table=11
                     /translation="MSELKPRITENGIDYILVGDYYIPDLKLPEERRPIGKYGRMHREY
                     LREVHPARLNTLILTGELWTYLADLNEQAQERLDTIMEQMKIAEGVTEKLKCTRQMEWV
                     RRCNNIHNRAEEIVLHEIIYS"
     CDS             13821..14321
                     /locus_tag="ctg157_16"
                     /transl_table=11
                     /translation="MPIIVLFIVYSSVKSNIILQDTDFLSLLMNHKGKFIFYFFVSFIE
                     EVIFRGIIFGLLLQKCKNKYLSCVIAALIFTLPHIFNTDNISVLVMFIFPFLYGIFANE
                     MFYTTKSIWMPTGFHWLWNYTITSLFLVTGTQSFIYVHIIAAMIIMIPLFYIVIGKTRL
                     SGD"
     CDS             14499..15440
                     /locus_tag="ctg157_17"
                     /transl_table=11
                     /translation="MKKKLCSMVCLCYFVSIMLCACGRKEQGNPIRLPAREDIVSIGVS
                     DGDKYAISPNTEGEATEFIDEFLSMLMDMETTSQQSINDAPVNKDSITININCDGEAGT
                     TLFYYVDKGIEYVEQPYQGIYKPTPALGNCITEMLASADNRPLMVTFQASVIETNHDSI
                     IVKPVDGSLELDSADKFYISNEENLELQIGDFVEISYNGEIMESYPAQLGEVYKITVIE
                     QTEANAMWDRIPMVRIDGKLYYDTGRESIMDARCGTMDGEITSTVDGTEIPTEDNQSNF
                     GSGFGYQYGADDTIEIYMNEKWFVFEYREESE"
ORIGIN
        1 acgaagaaaa accatgcctg ttttgatttt gatatccggt tcccaaagat gccttcctat
       61 ctgcgcagat ctgccatcca gcatgcattg gggacagtat cctcttataa aacacggctg
      121 gatctatggg aaaagatcga cggaaagagc gggaaaccaa agcttgtata tgaaaatcac
      181 gccatgccgg tcttctaccg tgatgtcatg tatcgtgaag gcgcggaagg gaaagacgaa
      241 gcatacctga aactctatga cggtcatgac tggaaatggt cctgtgtacg tctggatcat
      301 acggatatgg aatatctgag aaaatgctgg tcagggaaaa aggcatctgc cccgactctg
      361 gaaaagagac accagaagta ttttttgcgt ttttcctata aagaggaagt aacacttacc
      421 aaaacacctg tgaaagaaca gattatctgc agcgtggact tagggattaa taccgatgca
      481 gtctgtacta tcatgcgggc agacggaact gtcctgggaa gaagattcat agatcatccc
      541 agtgaaaaag accggatgta ccgcacactg ggacggatcc gcagattcca gagggaacat
      601 ggctctgcgc agacacaggg aagatgggca tatacgaaac gtctgaacac agaactgggt
      661 aaaaagactg caggtgcgat tgtaagatat gcggaagaaa accatgcaga tgtgatcgtg
      721 ttcgagtatc tggagatgca ggggaagata tcgggaaaga aaaaacagaa actgcacctg
      781 tggagaaaaa gagatatcca gaagtgttgt gaacatcagg cacacaggaa agggatgcgg
      841 gtatccagaa tctgcgcatg gaataccagc agattggctt atgatggttc cgggacggta
      901 acacgtgacc gggaaaacta cagcctctgt actttccaga caggaaaacg atataattgt
      961 gacctgtcag catcctataa tataggggcg agatatttta taagggaact tttaaaaccc
     1021 cttccggcaa cggaaaggtc tttactggag gcaaaagtcc ctcctgtaaa gcgtagaacc
     1081 tcatgtgttt atgctgactt aagagaactt catctgcaaa tggagatctt aaaagtagca
     1141 taaacacagg cagatataca gcggattacc tgtaatgtgg gaacctgccg tatccggcat
     1201 ggaaaaagca cataactgtg cagacctaag ttacaggcgt atccgccgat attcagtctg
     1261 acgcctaaag cgtctggaag cacgtgactt tagccatgtg aggttcacga ttatcggaaa
     1321 atgcctgtaa acagcgtaaa tacagcattt caaggagttt taagcaatga taagagtgtt
     1381 atttgtctgc cacggcaatg tttaatggat gccgtgaaag ccttgatttt attggatttc
     1441 ttgggaatta accaataatt tacaccttat ttataccttt ggaagaccgg atcggaataa
     1501 tataataaaa tttgctaatc tgtgttgatt ttttttatga ttgagtataa taaaatcaag
     1561 aacagaaatg ttctcgatgt aagagcatcg ttaaaagttg ggctgcagat ggagcagggt
     1621 aaacttccat ctcattagat gtcttaactg agcatcgagc ctggtagctt ggataaagct
     1681 gtagtccacg tgggggactt aatgattttc acgtcgttat gggtatctta actgggtatc
     1741 gaggctgaca accagcagaa aactctttta caaaagtaat tctcagaaga gtgtggttta
     1801 atgccacact cttttttgca tgtgaggtat aagtggcaac aaaggtagat aagaaaaacg
     1861 caatacgaca aggtattaca gaggcgtaaa tcgtatattt ccaaaatttg gcaggtaaaa
     1921 catttctgta tgtttgtgga gatgaatatt ttgaagtttc ttttccaata gatcactttc
     1981 tacatttaac aggagtggag acaagacttt cgaccaagga tttttataag aatgcaaaaa
     2041 aatctattct tacaaataat cagttctatt ttgacgcaag acatgtatat gcaaatgcca
     2101 aaaggaaact tccgtgttta aaacgcttgc cggaattaac gaatgaaatg gtatgtgttc
     2161 taaaaaatat ggaaaccatg acaattacat ataaactcag cgttacaaat ttggaattta
     2221 caggaagtgt gacaagaaag ccaaaacggt atactgggaa aaaagattaa gaaaagaata
     2281 aagagctggt tttaattgta aaatttatgg ggaactaaca tcagcttatt gacatgaatt
     2341 taaaaataag tataataata gttgagtaat tgttcaacta ttattatttg gaggtgaata
     2401 tatgccaaaa acgtcttata tttgtaattg cgatgtaatt catgaggata ttgtgaatga
     2461 tgtgaaatcc aagatgcagc caaaagatga ttatatccag ttggcttctt tgtttaagct
     2521 atttggagat ggaactagag tacaaatctt acacgctcta gaacagagtg agatgtgtgt
     2581 atgtgatctt gcagtgctac tgggggtaac aaaatctgca atttcgcatc agttaaaggc
     2641 attacgcctt gcgaatctgg taaaattccg taaagaagca cagatagttt actactcact
     2701 ggcagatgat catgtgaaag agattattga caagggattt gagcatcttt ggcagaaata
     2761 atatttttta acattatagt tgagtaattg aacaattaaa caaattataa ggagattatc
     2821 atgaaacgca tatttctatt aaaagggttg gactgtccaa attgttccgc aaaaattgaa
     2881 aaagaagtcg gagagttgga tggagtgcaa tcctcagtgg taaatctgat gaagcagacg
     2941 attacagtca atgttactca gacagccgca gatacgatag ccagtcagat tgaaacgatt
     3001 gtttatagtc atgagccaga tgtggaagtt caggaagaaa ccgttatgaa tgttacaaag
     3061 agttattcgt taaaagggtt ggactgtccg aattgttccg caaaaattga aaaagaagtc
     3121 ggagagttgg atggagtgca atcctcagtg gtaaatctga tgaagcagac gcttacaatc
     3181 aatgttgctc agacagccgc agatacgata gccagtcaga ttgaaacgat tgttcatagc
     3241 catgagccag atgtggaagt ttctgaaatt gtacaggaat cttatatacc ggaaaaaaag
     3301 caggaggcca atgaatccta taacaatgag gataagaagt tgacagttcg tttagcgact
     3361 ggtgcagcaa tctatgccat tggtatggca ttgactgttt ttgcgaaagt gccactgcct
     3421 atcgagttag cttttctcat tgtttcttat gttattcttg gtggagatat tgtatggcag
     3481 gctgtgagga acatttcaaa ggggcgtgta tttgatgaac attttttgat gagtgtttct
     3541 acgattgggg cttttgttat tggtgaatat ccagaagcag ttgctgttat gctattctat
     3601 caggtaggtg aattttttca gtcattggct gttaagcgtt ccagaaaatc tatatcagac
     3661 ttaatggata tacgtccaga ttctgctaca gtaagaagaa atggggaatt gattaccata
     3721 tctccagaaa atgtctccat tggtgagatt attattgtaa agcctggtga aaaaattcca
     3781 ttagacggtg tggtattgga tggagattct atgctggata caagggcctt aacaggagaa
     3841 tcagttccga gaagtgttca taaaggagac gaagcacttt ccggttgtat gaatcaaacg
     3901 ggtgtcttaa tgattaagac aacaaaagca tttggtgaat ctacggcttc aaagattatt
     3961 gatctggtgg aaaatgcgtc aagccgaaaa gcaccaacag aaaattttat tactacattt
     4021 gcacgttatt atacacctgt ggttgtaatc ttagcagctt ttctggcgat tctgccaccg
     4081 atcattcttg gcggaggctg gacagagtgg attcgcagag gatttgtttt ccttgtggta
     4141 tcttgtccat gtgcattggt tatttcaatc ccgctgactt tcttcggcgg cattggtgca
     4201 gcatctaaac gaggtgttct tgtaaaagga agcaattatt tagaggcact taataatgtc
     4261 agcgttattg tgttcgataa aaccggaaca cttacaaaag gtgttttcaa tgtgacggat
     4321 attttacctg caaatggatt ttcaaaagaa caggttctgg agtatgcggc agaggcagag
     4381 agtttttcta accatcctat tgcaaaatcc attcttgctg cttatgaaaa agaaattgat
     4441 cagtcagtga tttctgatta taaggaaatt tcaggatatg gaatcagtgt aatggcaggg
     4501 gaaaagaaag tttttgctgg caatacgaaa cttatggata cagaatgtat agagtacaca
     4561 acctgtgaaa aagcaggtac aaaagtttat ttggctgtag atggtcaata tgcaggatgt
     4621 attttgataa cagatgaagt gaagccggac agtaaaaaag caatttctga cctgaaacat
     4681 atcggcgtgg aaaaaacagt catgcttacc ggtgatgatg aaaaaattgg gaagtctgtt
     4741 gcagaagaat tgcagttgga taaatattat gcacagctgc ttcctgacca aaaagtggaa
     4801 aaggttgagc ttttagatag taaaaagaga ccgggaagca aattggcttt tgttggtgat
     4861 ggtatcaatg acgctcctgt ccttgcccgt gcagatgttg gtattgcaat gggtgggctt
     4921 ggttcggatg cggccattga agcagcagat gtagttctga tgacagatga accgtctaag
     4981 ctggtggacg cgattgaagt agcaaaagcg acaaaacaga ttgtcatgca gaatatagtg
     5041 attgctcttg ggattaagag tgtgttcctg attcttggcg ctcttggtat tgcgggaatg
     5101 tgggaagctg tatttggtga tgtaggcgtt accataattg ctgttttgaa cgcaatgaga
     5161 attttgaaaa aataggaaat gaggtggaaa tgtgaaacga aaactgattc tgttagttgt
     5221 tacgattgtt tttcttgtag gttttggtgt cattttacat tcaccgcctt ctatgattga
     5281 tgcagtcaca ggagcaacac cgaagtcaaa aaaggcggct caagcctccg cacagttgga
     5341 aggctcttat gttctcggta ttaatatgat gtcagatggt ctcgacaacg agaacacccg
     5401 gaataaatta aaagaattgg cactggacga ttcggaaaca aatgaaacag atctcatgaa
     5461 aacggacatt agttttcggt tatatgtatc tgagacggat tatccgcttg tcagttatgc
     5521 taagaaactc tgtgacaggt tgaaacaggc cggtttttcc gtagatctga aagagtacag
     5581 taacacaatg atgctatcaa gagtggtaag tggaaagtat gatgtattcc tggcatcgga
     5641 tgattttatt gacgttacaa cgctaacaca gatggactat atgatcatgg acagcgaaga
     5701 aatgaggtga gcgggaattt atgagaaaat ggaatacgat tttgtctgtt ttaatgcttc
     5761 tcatttttat gattcatgga atcatgggca gctttatgct gaacggagtt ggaagtagtg
     5821 cagggaaact tcttgcatgg attggtgttg gtattcttgt tgtgcatacg gtgattggtg
     5881 tcatcctgac agttcagagt ttacagacag cgaagcaatc cggaaaaatg tatctgaaac
     5941 agaacgccat attctgggcg agacgagcca gtgggctggc aatactgatc ctgctgttct
     6001 tccatattgg cttgtttgga aaggtgcaga atgggacata tattttgttc ccttttacaa
     6061 cggtaaagat ggtaactcag cttttgttcg tggcggcaat ctttgttcat atttttatca
     6121 atatccgccc attgctcgta tcgctgggaa tcatcagtta taaagaacga aggggtgata
     6181 tttatttgat tctttcggtg ctccttctgt ttatagcggg cgcagttatt ttctattata
     6241 ttgggtggca atatctatga gtaagacaat tattattata ggtgctggac tggcaggact
     6301 ttcagcggct ttgcaggcag cggaaaatgg atgcaatgta aaactggttt cctcccttcc
     6361 gtcagagcgg gcacagtctg ttatggcgga gggcggtatc aacgcagctt tgaatacaaa
     6421 agatgaaaac gacagtcccg aagaacattt tacagataca ataaaggcag catgtggtct
     6481 ggcagatcca aatgcagttt ggggaatgac acaggcagca ccggagctgg tgcactggct
     6541 gctaaaactt ggagttaaat ttaacatgag tggctatgat gatgtggatc tgcggaattt
     6601 tggcgggcag aaaaagaaac ggactgcttt tgcacagagc gataccggga agcagatcat
     6661 gacagctatg atagacgctg ttcgcaggaa agaagcatct ggtatggtag aacggttcag
     6721 ccatcattct ttcctaacac ttcgtctgtg tggcaatatt tgttgtggct gcgtaatcag
     6781 ggatgaatac agtcaggaga ctgtggaatt accgggggat gcggttattg ttgccaccgg
     6841 tggtatgcac ggattgtttg gaaatacaac gggttcgctg agcaatacag gagaagtcac
     6901 cgcagaattg ttccggcttg gtgttcctct ggcaaatagc gagatgatcc agtaccatcc
     6961 gacaactgtg aaatgtggtg gaaaacgcat gctcatcagc gaggcggcca gaggggaagg
     7021 tggcaggttg tttgccatga aagatggaaa acaatggtat ttcatggagg aaaaataccc
     7081 ggagcttgga aatctgatgc cacgagatat taccgccaga gagatatgga aggtcagcca
     7141 tgaatcagag gtatttcttg acatgacgga aatatcggag gagattattt caaataagct
     7201 atctggtctg gcagacgatt gtatgaccta tctgcataaa gatatacgaa aggaaccggt
     7261 gtctgtttta ccgggaattc actattttat gggaggcatt ctggtggatg agcagcacag
     7321 aacgccgatt cagaatcttt acgctgccgg agaatgctgt gcccaatatc atggtgccaa
     7381 ccgtcttggt ggaaattctc tgttaggagc gttatacgga ggacgtgttg cggcaaaatc
     7441 agcacgtgaa caggcagatg tagtagatct atcttgtgcg acacagatag attttccacc
     7501 aacgtctcaa atttcagaaa taaagcaatt aaacaaagtg atgcaggata ctatgggcgt
     7561 tgtcagaaat gagaatacgt tgttaaatgg gattcaaacg gtacaagcgc tgacaggaaa
     7621 tcttccattg cttggcatgg cagttctaaa gagtgctctt gcaagaaaag aaagccgtgg
     7681 tgcacactgg cgggaggatt atccgaagag caatgacgat gattacctta aaacaacggt
     7741 agccagattt gatggaaagc agatacagat ttcctttgta cctgttccag aaaggcggtg
     7801 attcacttgg tatataaaat aagaatcagg cggcaggaga gtcagaaatc agacagttat
     7861 tggcaggaat ttgagtttga cggaagcaaa aacagctctg ttgccaatgt tctaaaggaa
     7921 ttgaacagta gaaccccttt gaaagataat tcagggaata tagttactcc catcagctgg
     7981 gaatgtagct gtatggtgcg aaaatgtggg gcttgcgcca tgctgattaa cgaacgtccg
     8041 aggctggcat gctctacatt tctacatacg ttaaaaggtt ctacaatcac cttggaacct
     8101 ttaagcaaat ttccgcttgt aagagatttg atcgttgacc ggtcaattct gtttgaaaat
     8161 ttgaaaaaac tgaacctttg gcttgaaagt gaagcttata tgaatcggtg gacacatgaa
     8221 ccgagatacc agtcggcacg ctgtctaatg tgtggctgct gccttgaagt gtgtcctaac
     8281 ttctctgcaa atgggacttt cgcaggcgct gttgctgcag tcaacgcatt tcggattctg
     8341 aatgaagaac aggaaagcac tcatttgaat gagatttctg ctgaatataa gaagaaatat
     8401 tttgagggat gcgggaagtc gttatcttgt catgatattt gtccgattgg tctgcctgtg
     8461 gaagaactgc ttgtaaggtc gaatgcagcg gctgtttggg gcaaataaaa tggatgataa
     8521 aagctataat gaatgtatga agagaatcaa aaacttaaga catggatcac accggatctt
     8581 gcgacggagt atctcgcagg agccgtgctt ctcggagcag ctccatgtac cgctatggta
     8641 tttgtctgga gtacgctgac aaagggaaat ccggcttata cagtagttca ggtggcatca
     8701 aatgacatta ttatattatt tgcatttgta ccgattgtga aatttctgct tggtgtttct
     8761 aatgttagtg ttccgtttca gacgttattt atgagtgtgg ttctatttgt agtaatacca
     8821 cttgcagccg gaatcataac aaggctgctg gtagtcagaa agaaaggtac ggaatacttt
     8881 gagcagactt ttctgcataa atttgattcc gcaacaacag tgggactttt gctcacgctg
     8941 atactgattt ttatgtttca gggcgaggtg gtgctggaca atccactgca cattatattg
     9001 attgcagttc cgctgatcat tcagacattc tttatattct ttctggcatt tggagtatgc
     9061 agaattatca gacttccgta tgatattgca gccccggctg gaatgattgg tgcatcgaat
     9121 ttctttgagc tagctgttgc agtcgctgta gctttatttg gtacatcaag tccagcggca
     9181 ctggcaacta cagtaggtgt attaacagaa gtcccggtaa tgcttactct tgtgaagatt
     9241 gcaaacaaat taaaggagaa gttcaagtat gaataagaaa aaagttgctt ttatatgcgt
     9301 tcataattca tgcagaagcc agattgcaga agctttggga aaacatctgg cttcggatgt
     9361 atttgaaagt tattcggcag ggacagaaac aaaactacag attaatcagg atgcagtccg
     9421 gattatgaaa gaattgtatg gaattgatat ggaagcagaa ggacaatata gtaagctgat
     9481 tgatgagata ccagtaccgg atattgcaat ttcaatgggt tgtaatgtgg gatgtccgtt
     9541 tatcgaaaga ccgtttgatg ataattgggg acttgaagat ccaaccggaa agagtgacga
     9601 agagtttaag aaggttattg atgagataag gatgcaaatt tttatattga aacaacgatt
     9661 ggatgaattt gaagaaaact aaagaagttg agaaattgca gtttgtcgaa cggatgagat
     9721 acaaaaaaac atataagaat aatcaacaag gcaggtggtt ttataacaag actgtctgcc
     9781 ttcttttatg ccagcagagg ctatttcaaa ggggcatcca aaagacatac aatatatagg
     9841 ctcaaatggc gaaagtgccc atttgggcct attattgcat gaattcatat gttacatcca
     9901 gagcaagatc cacccgtgta ttacagtatt gtcattttga caattttgta ttacttacga
     9961 gtagcagact tgatggggat tacgtcccca tacccacgtg aaaatataat tgcaggcaat
    10021 tacattttag cagatacgca agcgtttctg agtaagtgtc acagacaaca aaataaggaa
    10081 attttgataa ggcattcacc tagaataggt gagtgttttt tgctttcaaa tattcaatta
    10141 accgaaaaaa ttaaaaaaat ttcatcaggg ggctgtaaaa atgcctctca gcgtttcgta
    10201 ttaatgaaag ggtatttggg cgggaaaaat aaaaaacttt cctcaagagc ctgtatttat
    10261 gcccttcatc ttttgaatat atgtaaggac atttttgagc cgacataaaa atgattttta
    10321 caataattag aaacagaaat gaggcgagaa aagaatcaaa tatgaataca tgaaggagtc
    10381 agagcagatg cttcagtact tccagtttcc gaagttttta ttaaagctgc gaatttctca
    10441 aactgcaaaa ttcctttata tgattttgta tgaccgggca cggatatcga gaaagaatag
    10501 ctggatagac aagtatggaa atgtggcacc tagtaaagta actgagaaat ataaaagtaa
    10561 taaatatcat gaagtaaatt attgctatgg ggaaggagag agtttgtgat gagagaagaa
    10621 gatactgtat gtgtaggcag tgatggcttg aaatactgca aagtctgtgg ggaagcgaaa
    10681 gaagcatttt tccccaaggg tggatttatg ggaatgaaga aacattccag gcaatgtgcc
    10741 tgtgacagaa aagtatatga agaagaacaa aaatatttta aagacaaaga gcaccgggaa
    10801 ttagtcagca gaaatacgag catctgtttt gacgagagca gaatggaaga gtggacattt
    10861 gagaatgcag atatgtcaga tacggtaatg catagagcaa aaaaatatgt tgataactgg
    10921 gaggaaatga aaagaaatca tataggctgt ttgttctggg gaccggttgg taccgggaaa
    10981 agttttattg cggggtgcat tgccaatgaa cttcttaagc aagaagtaat ggtaaagatg
    11041 acaaatttca ataccattat tgatgatata tttccactgg cagacaaaac ggaatatatc
    11101 aatgcattgg cgtcttatca gcttttgatt attgatgatc ttggagtgga acgaaattca
    11161 gaatatgcgt taggaattat ttttagcgtc atagatcgaa gaatccgttc aggacgacct
    11221 ttgatcatta cgaccaatct tccgctgaaa gaaataaaaa atgagaccat gttagataaa
    11281 agacgtatct atgaccgtat tttagaaatg tgtacgccta tgtatgttgg aggcacaagt
    11341 aagagagaag tgattgcaag tatgaaaatg gagaaagcga aaacgttgtt gaatacaaac
    11401 agaggggagg aggactgcga atgaatcata cagaaaaaac aatacctgtt tgggagaaat
    11461 attctttaaa tgtatccgaa gcagcagaat attacagaat tggagaaaag agattgagac
    11521 aaatcgcagg tgaaaatgag ggagcggatt tcattttgga agtaggttct catattcgat
    11581 tcaaaaggaa attgtttgaa gattatctgg atacagccag cacagtttaa gtgacagaat
    11641 agaagaaata gtaatgaaaa taatgttcat tttatcttag cgaaggaaag gtcttgtggt
    11701 ataatgaata aaccgagacg gtcttccaag ttaaatgaac atttgatgaa ggagactaaa
    11761 atattatgag tgaaaaaagg agagatcata gaggacgtat attacacaat ggagaaatac
    11821 agttatctga tggcagatat cgatttaagt atgtcgatga gatgggaaag gagcgctgcg
    11881 tatatagctg gcgcttagac cataacgatg caactccgaa aggaaagcgc cgtactttgt
    11941 cgcttcggga gatggagaag aaaatcgagg cggaccattt tgagcagatt gcaacaaatg
    12001 gcggaaatat gacggtactg gaactggttg aaaaatatac atcaacaaaa accggtgtca
    12061 gacctactac agttgcagga tacggaacag ttatcaattt attgaagaaa gatccatttg
    12121 gaaaaagaag gattgatacg gttcggattt cggatgcaaa atgttggctg atacatcttc
    12181 agcaggtaga aaagaaaagt tatagttcca tccattcaat ccgaggagtt cttcgtccgg
    12241 catttcagtt ggcagtggat gatgacctga tcaggaaaaa ttcatttcag tttcagctaa
    12301 tggaagtggt tgtgaatgac agtgtgacaa gagaggcaat cagcagggct gaggaacgaa
    12361 agttcctacg gtttgtgaag gaggatcctc atttttgcag gtattatgag gggatttaca
    12421 tattatttaa aaccggcctt cgcatctcgg aattttgtgg tttgaccatt tctgacattg
    12481 attttaagga gcatacgatc aacatcgatc atcaattgca gaaaaaatca aaaatcggat
    12541 attatattca agagactaaa acaaccagcg gaacgagaaa gatacctatg actgcagatg
    12601 tagaggaatg ctttcggaaa ataatagaaa aacgaaaccc acccaaagca gaacctatgg
    12661 tagatggaaa aagtggattc ttatactttg ataaaaatga aagtatctgt tattccctgc
    12721 actgggagca ttatttccaa cacatcattc agaagtataa taatacttac aaagtacaga
    12781 tgcctgtcat tacaccgcat gtatgccgac acacctattg ctcaaatatg gcaaaatccg
    12841 gaatgaatcc aaaagcattg caatatttga tgggccactc agatatcagc gtaacgctga
    12901 atacatatac gcatgtaaat cttgaggatg ccagggaaga agttgcccgg attcaggttg
    12961 tgtaattacg atttttaatt gaaaacagca aggtgtaaaa tggaaaaaca tacaccttat
    13021 tttacacctt ttgctgacga tattatgcga aaataaacca ggttatgcca gaaagcaaaa
    13081 atttacaaag gcttacaaat cccgaaaaac caagaaaaac taagaaatgc gaggttatgc
    13141 aacaatgata aaagtactct ttatctgcca cggcaggatt taccgggcat gatgaaaagt
    13201 ctcatatcgt ctcataagcc ccgtttttaa gcgttttttg tgcttcagtc tcaaatttac
    13261 caaagattta ccaatatttc tggagagcca gacttgcaaa aaaataagcc agaatgagga
    13321 gattaaaaca tgagcgaatt gaaaccaaga ataacggaaa acggaattga ttatatcctt
    13381 gttggagatt actacatccc agacttgaag ttgccggaag aacgccgccc catcggaaag
    13441 tatggacgga tgcaccggga atatttaaga gaagtccacc cagccagatt gaacacattg
    13501 atactgaccg gagaattgtg gacatatctt gcagacctga acgaacaggc acaggaacgg
    13561 ttagacacta tcatggagca gatgaaaatt gccgagggcg taaccgagaa attaaagtgt
    13621 acccgtcaaa tggaatgggt gcggcggtgc aataatatcc acaatcgggc agaagaaatt
    13681 gttttgcatg agataattta ttcataatag tatggtgtca ggattatgac aaatcagagg
    13741 ttaaaaggtg cgttatgtta aaaagcatag ggttatattt tagaaaaata gattttctga
    13801 attttgcaat tggagctata atgccaatca ttgtattgtt tatagtttat tcatcagtca
    13861 aatcaaatat aattcttcaa gatactgatt ttttatcact gttgatgaat cataaaggga
    13921 aattcatatt ttactttttc gtgtccttta ttgaagaagt tatttttaga ggaattattt
    13981 ttgggctgtt gctgcaaaaa tgtaaaaata agtatttgag ttgcgtaata gctgcactta
    14041 tttttacact accacatatt tttaataccg ataatatttc tgttctggta atgtttattt
    14101 ttccttttct atatggaata tttgccaatg aaatgtttta cactacaaag agtatttgga
    14161 tgcccacagg atttcattgg ttatggaatt atacaataac aagtttgttt cttgttacag
    14221 gaacacaaag tttcatatat gtacatatca tagcagcaat gattataatg ataccgttgt
    14281 tttacattgt tattgggaaa acacgcctaa gtggcgattg atagcttaca gtttatcgct
    14341 ttatacaact cccttttcgg aattgtgtac ccactgaaaa cgagcctata aacatgcatt
    14401 cacaatgcat aaaaacacgt tctggctatt tcccacacat tgaaatatac acttagataa
    14461 cgtataatac gaaatatatt ttggggagga ttatgaccat gaaaaagaaa ttatgcagta
    14521 tggtttgtct ttgctacttt gtttcaatta tgttatgtgc atgtggaaga aaagaacagg
    14581 ggaatcctat tagattgcca gccagagagg atattgtatc gattggtgtc tctgacggtg
    14641 acaaatatgc tatatcacct aacacagaag gtgaagctac ggagtttatt gatgaatttt
    14701 tatctatgct aatggatatg gaaacaacca gtcagcaatc aatcaatgat gcaccggtca
    14761 acaaagattc tattacgatc aatataaatt gtgatgggga ggcaggaact actctttttt
    14821 actatgtaga taaaggaatc gaatatgtag aacagccata tcaaggaatt tataaaccaa
    14881 cgcctgcttt aggtaattgt ataactgaaa tgcttgcttc ggcagataat agaccgctaa
    14941 tggtaacatt tcaggcatcg gtaattgaaa cgaatcatga ttcaataata gtaaaaccgg
    15001 tagatggttc tttggaactt gattcagcag ataagtttta tatatcaaac gaagagaacc
    15061 ttgaattgca aattggagat ttcgtagaaa ttagctataa cggagaaata atggaatcat
    15121 atcctgcaca attaggagag gtttataaaa ttaccgtgat agaacagaca gaagcaaatg
    15181 ccatgtggga tagaatacct atggtaagaa tagatggtaa attatactac gatacaggga
    15241 gagaaagcat catggatgca cgttgtggca ctatggatgg agaaataaca tcaactgtcg
    15301 atggaactga aataccaaca gaagataatc agtctaattt tggaagtgga tttggttatc
    15361 agtatggagc agacgataca atagaaattt atatgaatga aaagtggttc gtctttgaat
    15421 acagagaaga atctgaatga gagaataaac gatagataag ttaaattaaa ttcaaaaggc
    15481 tgtctcaata aagggatagc ctttttcaat tctcagccta aattttctca atattcagta
    15541 ggcaaaatcc aagatacagt tgctcaaatt gctcgaaaaa ttaaaaaatg tatgaatata
    15601 cactaaaatt tgggaaatga acagcgggaa cacttttccg aaaagggagt tatacaatat
    15661 caactgaata accacagcac aaaccgctgc tacatggaag ctaacaaacc atgcaacagc
    15721 ggtttttctt gttagggcaa agccctgttt gccattgtgg agtttttcgc tgatccgaaa
    15781 aacggagctt tggaaaacaa ataaa
//
