LOCUS gnlProkkaEOGDNDGO_146 14331 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|EOGDNDGO_146. ACCESSION gnlProkkaEOGDNDGO_146 VERSION gnlProkkaEOGDNDGO_146 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2024-12-01 00:26:28 Original ID :: gnl|Prokka|EOGDNDGO_146 NOTE: This is a single region extracted from a larger record! Orig. start :: 0 Orig. end :: 14331 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..14331 /aStool="rule-based-clusters" /category="RiPP" /contig_edge="True" /core_location="[7057:7742]" /cutoff="20000" /detection_rule="(TIGR04223 or AgrB)" /neighbourhood="10000" /product="cyclic-lactone-autoinducer" /protocluster_number="1" /tool="antismash" proto_core 7058..7742 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="(TIGR04223 or AgrB)" /neighbourhood="10000" /product="cyclic-lactone-autoinducer" /protocluster_number="1" cand_cluster 1..14331 /candidate_cluster_number="1" /contig_edge="True" /detection_rules="(TIGR04223 or AgrB)" /kind="single" /product="cyclic-lactone-autoinducer" /protoclusters="1" /tool="antismash" region 1..14331 /candidate_cluster_numbers="1" /contig_edge="True" /product="cyclic-lactone-autoinducer" /region_number="1" /rules="(TIGR04223 or AgrB)" /tool="antismash" CDS 106..903 /locus_tag="ctg146_1" /transl_table=11 /translation="MILAVISALCLAELLIVEKELKNRILLVLFGCCVLAVVLLIFYLY DVLISAYKKLEEQSLMEKQMLIYSHQLDVLMQSEEKVKALRHDMKNHLGELALMAGNQN NEEIRKYIHDMGEYMQNQSELVSCGNKNLDSLLNYLLGQAKKKLNHVEYEVRVPSDLCI SAFDLNVILGNLTENAIEAAEQTKDKWMSVDIYYEKGILSMEIKNSFQHELAVEKNKLL STKEEKGHGIGLANVRKMVEKYQGFMDVSNTNQIFTVKVMLYL" CDS 1317..1700 /locus_tag="ctg146_2" /transl_table=11 /translation="MLSKKLKKVILGFVTALCLTGSAMPVMADTVRFNVTVPGDPKSKR IPKSDDEQKFYVTGTYFSSYGTLSCRSYQLENQHVFSETKDISRTAPSNKGKYKSWAKP HVYYFMSSHSSLNGMNVEGRYTP" CDS 1728..2825 /locus_tag="ctg146_3" /transl_table=11 /translation="MEILPFSLRERKTMKIKAMAVIKITISCLIFFNSINTCFAADFPS TYEKSSEKVKFDCELEIPKDFSETEMYSEKTKGRIYPDMDKTISIYTQGKEVKENGTIP AASSEDPEGVYYVFTDGSTLSVDSSFTYGSDTAKYYGYIGVRDPQYKERFEQQTVSFMD KNTVIEKVSSDLENIGIDTTDISWDAYPLNHEAMSQLENEQISDGLDMEEHRKESWTEE DDAYFVYGVQMSQKLPVFHELMNTSRQLAYDTPDSSVIQAIYSKRGVEILSYSGYMYKF DVSDQKINFLAFDDIASVVFDKFNNLLNESTYKITRAKLYERVFLNEAQQMEVSPVWYF EILQDDDTTSITLVDAVSGEEIYLE" CDS 2844..3614 /locus_tag="ctg146_4" /transl_table=11 /translation="MNYKSKGLLIKSDLSRLLKCYKIYAAIIGVSIAILFSTEQIGLIN GNILDTYIQGSELSGIMIAYVFCAFPFATVFCEDLDNKYIRYELIRSNLKRYVVTKIAF IYLTAILVMVLGTILFLLSGRIAGGDWVNESVGCMNVLLNGSYSILLKKEHYFLYCVMY SLQLGLLSGLLSVLAGYFSLYIHNRVTVLALPIIIYQILIECSGNTIYTVFIFRAYNRP MNKDWESFSLILLISIIPTILLGCLIYKKIQKRL" CDS 3618..4481 /locus_tag="ctg146_5" /transl_table=11 /translation="MFKIMKYILKNTLLKIRNIKTITFAIIIAVTIWSYNHPLRELTYS IKYPVTWCVFPFMISNLSFLILFWFGIIYINSDIPYMQHSNMYQIIRTGRISWALGQLG GTFFRSFILVVFTAFCSIVSLLPQIEWSLQWGKLIHTIAMTNAAIQYNLKYVFYYQILG KYSPLQLMIITIVICTFISMFLSSLMFMISLYFNHILAVSITAALTIMLFFVVNIHPKI RYILAKFIPTVWAKVVQVNSPVLGYYWVPSIKYMFAFLLIGNIILIILILIKVKKCEFN WENEDI" CDS 4496..5152 /gene_functions="transport (smcogs) SMCOG1000:ABC transporter ATP-binding protein (Score: 174.6; E-value: 4.2e-53)" /gene_kind="transport" /locus_tag="ctg146_6" /transl_table=11 /translation="MNEKKYIIEVSHVNKSFKNNKVLKDVTLRCESGRIYGLVGHNGSG KTVLFKTICGFLACDEGTVSVNGKVMGKDKDMLTEAGIIIEDPGFLRNWSAYHNLEFLY TIRNRPDKSYLHSVLNTVGLDPKLKRPVGKFSLGMRQRLALAQAIMEDPPILILDEPMN GLDKNGVAEIRELLLKMKNENKLIILASHNREDIEILCDEVYEMEDGILRKIVKE" CDS 5390..6112 /locus_tag="ctg146_7" /transl_table=11 /translation="MLYIGICDDDEGVCAELERMLYDYAEQNKIQMDIDIWHRGESLCR FLREKEQISDVLFLDIELLTTNGIEVGRFIREEQENMETAIVYISANSSYAMDLFRVQP TDFLIKPLDKIKVGNVMDRIQKISEVRKGIFEYFVSGYYFKVLYKDILYFSSQNKKVHL VLKDGQKEFNGKLKEIAKKIPGNFIQIHQSYLINFDYIEECSYESVKMKNGDTIPISQP YRKSVRKQLAERVWRDRE" CDS 6205..6537 /locus_tag="ctg146_8" /transl_table=11 /translation="MLIYSHQLDVLMQSEEKVKALRHDLENHLGELAFMAGNQNNEEIQ KYIQDMGEYMQNQSELVSCGNKNLDSLLNYLLGQAKKKLNHVEYEVQVPSDLCISAFDL NVILGN" CDS 6583..6810 /locus_tag="ctg146_9" /transl_table=11 /translation="MSVDIYYEKGMLSMEIKNSFQHELDVEKNKLLSTKEEKGHGIGLA NVRKMVEKYQGFMDVSNTNQIFTVKVMLYL" CDS 6825..7031 /locus_tag="ctg146_10" /transl_table=11 /translation="MKDSVVVGLRCLLFCRKLVKRENIVTENLIKNHNMFSKNEFRQFI YEFRHFRKFCNKYDIIQIQSKKK" CDS 7058..7192 /gene_functions="biosynthetic (rule-based-clusters) cyclic-lactone-autoinducer: TIGR04223" /gene_kind="biosynthetic" /locus_tag="ctg146_11" /sec_met_domain="TIGR04223 (E-value: 4.1e-18, bitscore: 55.4, seeds: 127, tool: rule-based-clusters)" /transl_table=11 /translation="MRKELKKVIEKIAIKAASSNVNETCSWITYQPKVPESVKKLKKH" CDS 7194..7742 /gene_functions="biosynthetic (rule-based-clusters) cyclic-lactone-autoinducer: AgrB" /gene_kind="biosynthetic" /locus_tag="ctg146_12" /sec_met_domain="AgrB (E-value: 1.6e-38, bitscore: 122.1, seeds: 181, tool: rule-based-clusters)" /transl_table=11 /translation="MEIQTFSEEEKEEIIRYGLDKIKNSCMMSAVTLLMGYAFHVFLQS IVFLICFIALRKYAGGYHADTQKRCYVISVLIIAVALWATRYKSDNSVCFVFIQSLNFI ILCFLVPVDSKNRRLEQWEKERYGKKAKVQIFCMYMLCLILYLDKKQSIAVAIGVANLT VGGCVCAGKMKNILLKHKE" CDS 8142..9167 /locus_tag="ctg146_13" /transl_table=11 /translation="MEKYIIMKKVNKFKLLAAGLLIGVAFWLLGSDFFTFMIWWEILWI LGLVFMPITAQIFKGFDDNGWMNSKVIAIVICGYGVWILTSIKVVHFTTLSSVVITTLC GGSSIAYGIYGKQRKVFPWKHMELVYWEEVIFFVVFLLWTYMAGFHPAAHGTEKYMDFG FMKSMMHSTTLPSEDMWYAGKAFNYYYGGQYFAVFLTKLTGTKVEITYNLMRTMIAAFA FVLPFSLVRQMLKDKLGKRGRAWITDFGGILAGLSVSMSGNLHYIIYGKIFTLLGIRED YWFPSTTRFIGFDPPVTGDETIHEFPSYSFVLGDLHAHVINVFFVLAVGDFICMDKKKF R" CDS 9316..10389 /locus_tag="ctg146_14" /transl_table=11 /translation="MKPSDMRTGIKWSVVQWIELLLTAVLISLPFHLQFKSVMVQGIGI VKIHTAFYQFCVLWAFPLLICGLFVVSTLIKNRNFTNKKTRNLFYKINVSDLYGVVLSL CAMGLILIPEIVYVSDIYEKTAPRANTMFKLTYQAYILFALMMSYILVFFVADRIKILQ ETKLDNRYEKKVRLSKVQITVGGMAIILLISTCGYFINATTNWFTGFPLKNKYQTLNAT AYLENAIPEDAAAIRWLNKNITGQPTVLEACGDSYKDYDNRVSAMTGLPTVLGWYVHEW LWRNNLDEENKRRTDVETIYTSTDKKEVQELLDKYEVNYIFIGSCEYQKYEGVNVALLS SLGEIVFKEENTMIVKL" CDS complement(11066..12643) /locus_tag="ctg146_15" /transl_table=11 /translation="MKKINNIIYSNPKQAVLPMLIQDYLDICDPVLTFDRFMGEIELEK YLKNIPQHYTGRFRYAPVSMLKTVLFGFMANGYISLRELEDQCKVNLRFMYLMDHQTPS YRTFGYFINEVLADSIEEIFRDINKKIFETEHVDLQHLYIDGSKFEANANKYSWVWKKA TEKSRYRLFDKITELFKEINEELSCTGIKLCINSEYAPEYLKEAAEQYAEAWQIDETIF VHGRGHRKTTQQRHYEKLREYTTKLEEYVEKIKICGEERNSYSKTDYSATFMRIKKDYM GNDQLLPAYNVQVGVADEYIAVVDVNQYRSDMDCFIPLMNKFYTTYGFYPKYPVADAGY GSYNNYIFCEQHGMKKYMKFPMFKKETTDKKYHEDPFRAVNFPIGKDGIMRCPNGKRFY LQYQKNVKGNKYGRQEEVYQCEDCSSCPYAEQCKKTDKNRTVRINRELTAMHQEVIENL ESIQGALLRMNRSIQAEGTFDIMKNDRWYKRIVRRGIKSVLLEVFLVSIGHNLYKYHNK QKKGATAA" CDS complement(12741..13319) /gene_functions="biosynthetic-additional (smcogs) SMCOG1039:aldo/keto reductase family oxidoreductase (Score: 161.7; E-value: 3.8e-49)" /gene_kind="biosynthetic-additional" /locus_tag="ctg146_16" /transl_table=11 /translation="MDPETPLEETMGALDSIVRSGKALYVGLSNYDGPTLKKATEILTY LKCPFVINQNRYSIFDRTIENNGLKDTAYELGKGIIAFSPLAQELLTKRYLNGIPADSR IATDGRFLNETALTSEKLSQIQALNEIAMERGQTLAEMALSWILKDDKVTSVLIGASKP EQILDNIKIIGHTDFSDEELKKIDDIVNS" CDS complement(13425..13748) /locus_tag="ctg146_17" /transl_table=11 /translation="MEVYTHVHCRQKRYDAIVYNRCGKSGLKLPVVSLGLWHNFGDTSV YENMKQMCFTAFDNGITHFDLANNYGPAYGSAERNFGKLFREELHPYRDEMLISTKAGF DMW" CDS complement(13987..14106) /locus_tag="ctg146_18" /transl_table=11 /translation="MKHKALKKIEGGKSTQRVNIQKQKIKVQKLHLELLEKLQ" ORIGIN 1 tatacagctt aagcaacaag atggataatt ccttactggc tgtaagggat attaaccata 61 aatatattgt agtagaataa aggagaagat aaaactccgc atgggatgat actggcggtt 121 atttcagcac tttgtctggc agaattgctt attgttgaaa aggaactaaa aaatcgtatc 181 ctgctggtgt tatttggatg ttgtgttttg gcagttgtat tattgatttt ctatttatat 241 gatgttctga taagcgcgta taagaaactg gaagaacaat ctcttatgga aaaacaaatg 301 ctcatttatt ctcaccagtt ggatgtgttg atgcaatcgg aagagaaagt aaaagctcta 361 cgccatgata tgaaaaatca tctgggagaa cttgcactta tggctggaaa tcagaataat 421 gaagaaattc ggaaatatat acatgacatg ggggagtata tgcagaatca gtctgaactg 481 gtcagttgtg ggaataagaa tcttgacagt ctgctgaatt atcttctggg acaggcaaaa 541 aagaaactga atcatgtaga gtatgaggta cgggtaccat ctgatttgtg tatatcagca 601 tttgatctga atgtgatttt gggaaacctg acagagaacg caatagaagc agcagaacag 661 acgaaagata aatggatgtc agtggatata tactatgaaa agggcatcct ttccatggaa 721 ataaaaaaca gctttcaaca tgaattggct gtagagaaaa ataaattatt gtcaacgaag 781 gaagaaaaag gacatggcat tggtcttgca aatgtcagga agatggtaga gaaatatcag 841 ggatttatgg atgtttcgaa tacaaatcag atttttactg taaaggtaat gctgtactta 901 taaattatgt agaatctatg aaagatagtg tagtggtagg actgcgctgt cttttatttt 961 gcagaaaatt agtcaagagg gaaaatattg tgacagaaaa ccttataaaa aaccacaata 1021 tattctgaaa aaacgaattt cgccaattta tatatgaatt tcgccgtttc agaaaatttt 1081 gcaataaata tgctattatt taaatacaaa ctataaatga gcaagttcgt gattttgcat 1141 aaaaaaaaag acaccttaaa tccagtgttg attttgaagc gtttatgaaa ttagcaggat 1201 agttttgtac attttttcaa atttgctcat ttatagctat aataacactt gtcgttggtt 1261 tactgcaaat tacgcgcgtg gttaaaatga caaaaaataa acaggaggtc aaatgtatgc 1321 taagcaagaa attaaaaaag gttattttgg gatttgtaac tgcattatgc ctgactgggt 1381 ctgcaatgcc cgtaatggct gatactgtcc ggtttaatgt gacagttccg ggagatccta 1441 aatcaaagag aataccaaag tcagatgatg aacaaaaatt ttatgtgact ggtacatatt 1501 tcagcagtta tggaacattg tcgtgtcgat catatcagtt ggagaatcag catgtctttt 1561 ccgagacgaa ggatattagc cgtactgcac caagcaataa gggaaaatat aaaagctggg 1621 caaaacctca tgtatattat ttcatgtcat cacattcgag tttgaatggc atgaatgttg 1681 aaggaagata cacaccgtaa tattcatatt aaaaagaaaa aggcaggatg gaaatcttgc 1741 ctttttcgct aagggagaga aaaacaatga agattaaagc gatggcagtt ataaaaatca 1801 caattagttg tttgatattt ttcaatagta ttaacacttg ctttgcagcg gattttcctt 1861 ctacctatga aaaaagcagt gaaaaagtga agtttgattg tgagttagaa attccaaagg 1921 atttttcaga aactgagatg tactcagaaa aaacaaaagg ccgaatttat ccggatatgg 1981 acaaaacgat ttcaatctac acgcagggaa aagaagtaaa agaaaatggg acaataccgg 2041 cagcgtcttc agaagatcct gaaggagttt attatgtctt tacagatggc tctacattat 2101 ccgttgacag ctcttttaca tatggttcag ataccgcaaa gtattatgga tatattggag 2161 tacgtgatcc tcaatataaa gaacggtttg aacaacagac agtttctttt atggataaga 2221 atacagtaat tgaaaaagta tcttcagatt tggaaaacat tggcattgat acgactgata 2281 tatcctggga tgcttatcct ttaaatcatg aagctatgag tcaattggaa aatgaacaga 2341 tttctgatgg gctggatatg gaagaacacc gaaaggagtc atggacagaa gaagatgatg 2401 catattttgt ctatggcgta caaatgagcc aaaaattgcc agtatttcat gaattgatga 2461 acactagcag acagttggct tatgatacac cagacagttc tgttattcaa gcgatttatt 2521 caaagagagg cgtagaaatt ctttcttact caggatatat gtataaattt gatgtatcag 2581 accaaaaaat aaattttctc gcatttgacg atattgcttc agtcgttttt gataagttta 2641 ataacctgtt aaatgaatca acctacaaaa taaccagagc aaaattgtat gagagagttt 2701 ttctgaatga agcgcagcag atggaagtta gccctgtttg gtattttgag attcttcagg 2761 atgatgatac gacatccatt accttagtag atgctgtttc gggggaagaa atatatctcg 2821 aataggaaag gctggagaaa aagttgaact acaaaagcaa aggtttactc ataaaatctg 2881 atttaagcag acttttaaaa tgctataaga tatatgcggc aattatcgga gtaagtattg 2941 caatattatt ttctacagaa cagataggat tgatcaatgg aaatattttg gatacatata 3001 ttcagggatc agagctttcg ggaatcatga ttgcatatgt gttttgtgca tttccatttg 3061 ctactgtatt ttgtgaagat cttgataata aatatatacg atatgaattg atcaggagta 3121 atttaaaaag atatgtagtt accaaaattg ctttcatcta tttaactgca attttggtta 3181 tggttttagg aacgatactt tttttattat cgggacgtat agctggtgga gattgggtaa 3241 atgagtctgt gggatgtatg aatgttttgc tgaatggaag ttattccata ttactgaaaa 3301 aagagcatta ttttttatat tgcgtaatgt actctttgca gcttggattg ttatccggat 3361 tactatctgt attagctggt tatttttctt tatatattca taatcgtgtc actgtattag 3421 cattaccgat tataatatat caaattctga tagaatgctc tggaaatact atttatactg 3481 tatttatttt cagagcctat aatagaccaa tgaataaaga ctgggaaagc tttagtttga 3541 ttcttttaat aagtattatc ccaacaattc tattaggctg tttgatatac aagaagattc 3601 aaaagaggtt ataaaatatg tttaagatta tgaaatatat tttgaaaaat actttactga 3661 aaataagaaa tataaagact atcacatttg caattattat cgccgtaacg atatggagtt 3721 acaatcatcc tctgcgagaa ttgacttact cgatcaaata tccggtaaca tggtgcgtat 3781 ttccttttat gatttcaaat ttgtcttttt tgatactttt ttggttcgga ataatctata 3841 taaattcaga tattccatat atgcagcaca gtaatatgta ccagattatc agaacaggac 3901 gtataagttg ggctctggga caattaggtg gaacgttttt tcggtccttt attcttgtag 3961 tttttacagc attttgctca attgtttcat tacttccaca gatagaatgg agccttcaat 4021 gggggaagct tatccatacg attgctatga caaatgcagc aatacagtat aatctgaagt 4081 atgtgtttta ttatcagatt ttaggaaaat attcaccatt acaattaatg atcattacaa 4141 tagtcatatg cacatttatt tccatgtttt taagttcctt aatgtttatg ataagcttat 4201 atttcaacca cattttggca gtctcaatta cagcagcatt aacgataatg ctattttttg 4261 tggtaaatat ccatcctaaa atacgatata ttcttgcgaa atttatccct actgtatggg 4321 caaaggtagt gcaggttaac tctcctgtgc ttggatacta ttgggtacca tctataaagt 4381 atatgtttgc atttttgtta ataggaaaca ttattttaat aattttgatt cttataaaag 4441 taaagaagtg tgagttcaac tgggaaaacg aggatatata ggaggaataa ctgctgtgaa 4501 tgaaaaaaag tatatcatag aggtatcaca tgtcaataag agttttaaga acaataaagt 4561 cttaaaggat gtcacgctca gatgtgaaag tggccggata tatgggctgg tcggacataa 4621 tggctctggg aaaacggttt tgtttaaaac aatttgtggc tttctggcct gtgatgaagg 4681 aacggtttct gtaaatggaa aagtaatggg gaaagataag gacatgctta cagaggcagg 4741 gatcattatc gaagatcctg ggttcttacg aaactggagt gcttaccata accttgaatt 4801 tctgtacacg atacgaaata gaccagataa atcatatctg cattcagtgt taaacacagt 4861 tggacttgat ccgaaattga aacgcccggt tggaaaattc tcgcttggta tgcggcagag 4921 gctggcactt gcccaggcta ttatggaaga tccaccaatc ctgatcttgg atgagccaat 4981 gaatggtctt gataaaaatg gtgtagcaga aatccgggag cttttgctga agatgaagaa 5041 tgaaaataag ctgattatac tggcaagtca taatcgggag gatatagaga ttctatgtga 5101 tgaagtatat gagatggaag atggaatact tcgaaaaata gtcaaagagt aagaaaaaat 5161 atttcgtata gtttatattt cattttatct atagcacaac aagttaaatt atattgacag 5221 aaaaattctc accactctga cgcgggattt cacactctga tgggctggat taagatgcat 5281 tatttacgag gattgctata gtttccagag ctttgggagt gtgattattt ttatattgaa 5341 aaagaatgcc aatggttata tacttctggt agtatgaaag gagtagaaaa tgttatatat 5401 tggcatttgt gatgacgatg agggcgtttg tgctgaattg gaaagaatgc tttatgatta 5461 tgcggaacaa aataaaattc agatggatat tgatatttgg cacagaggag agagtctgtg 5521 cagatttctg agagagaaag agcagatttc ggatgtgttg tttctggata tagaattact 5581 gacaacaaat ggaattgaag tgggacggtt tataagagaa gagcaggaaa acatggaaac 5641 tgcaattgtt tacatttcag cgaacagcag ttatgcgatg gatttatttc gtgtacagcc 5701 gacagatttt ctgatcaaac ctttagacaa aataaaagtt gggaatgtca tggacaggat 5761 tcagaaaatt tcagaagtca gaaaaggtat tttcgagtac tttgtcagtg gatattattt 5821 caaggtgctg tataaagata ttctgtattt cagcagtcag aataaaaaag tgcatctggt 5881 tttaaaagac ggacagaaag aatttaatgg caaactgaaa gaaatagcaa agaaaattcc 5941 gggaaatttc attcagattc atcagtcgta cctgatcaat tttgattata tcgaagaatg 6001 ttcttatgaa tctgtgaaaa tgaaaaacgg agatacaatt ccgatcagcc agccatatcg 6061 gaaatcagtg agaaagcaac tggcggaacg tgtgtggagg gacagagagt aaatgtttgc 6121 gttgataact agattttcta tttatatgat gttctgataa gtgcgtataa gaaactggaa 6181 gaacaatctc ttatggaaaa acaaatgctc atttattctc accagttgga tgtgttgatg 6241 caatcggaag agaaagtaaa agctctacgc catgacctgg aaaatcatct gggagaactt 6301 gcatttatgg ctggaaatca gaataatgaa gaaattcaga aatatataca ggacatgggg 6361 gagtatatgc agaaccagtc tgaactggtc agttgtggga acaagaatct tgacagtctg 6421 ctaaattatc ttctgggaca ggcaaaaaag aaactgaatc atgtagagta tgaggtgcag 6481 gtaccatctg atttgtgcat atcagcattt gatctgaatg tgattttggg aaactgaata 6541 gagaacgcaa tagaagcagc aaaacagacg aaagataaat ggatgtcagt ggatatatac 6601 tatgaaaagg gtatgctttc catggaaatt aaaaacagtt ttcaacatga attggatgta 6661 gagaaaaata aattattgtc aacgaaggaa gaaaaaggac atggcattgg tcttgcaaat 6721 gtcaggaaga tggtagagaa atatcaggga tttatggatg tttcgaatac aaatcagatt 6781 tttactgtaa aggtaatgct gtacttataa attatgtaga atctatgaaa gatagtgtag 6841 tggtaggact gcgctgtctt ttattttgca gaaaattagt caagagggaa aatattgtga 6901 cagaaaacct tataaaaaac cacaatatgt tttcgaaaaa cgaatttcgc caatttatat 6961 atgaatttcg ccattttaga aaattttgca ataaatatga tattattcaa atacaaagta 7021 agaagaaatg aaatatatgt gaaaggagaa taagaaaatg agaaaagaat taaaaaaagt 7081 cattgaaaaa attgcgatta aagctgcttc ttcgaatgta aatgaaacat gttcatggat 7141 tacatatcaa cccaaagtac cagaatcggt aaaaaaatta aaaaaacatt gatatggaaa 7201 tacagacctt ttcagaagaa gaaaaagaag aaatcattcg atatggactt gataaaataa 7261 aaaattcctg catgatgagt gctgttacac tgctgatggg atatgccttt catgtgtttt 7321 tacaaagtat agtttttctt atatgtttta ttgctttaag aaaatacgca gggggttatc 7381 atgctgatac acaaaagcgg tgttatgtaa tttctgtatt gattattgcg gttgcattat 7441 gggcaaccag atataagtct gataatagtg tgtgttttgt ttttatacaa agtttaaatt 7501 ttataattct gtgttttctt gttcctgtgg atagtaagaa tcgacgtctg gaacagtggg 7561 aaaaagaaag atatggaaaa aaagcaaaag tacaaatatt ttgtatgtat atgttgtgtt 7621 tgattttgta tttggataag aaacaaagta tagctgttgc tattggcgtg gcaaacctga 7681 cagttggagg atgcgtatgt gcaggaaaaa tgaaaaatat tttactgaaa cataaagaat 7741 aatttagaaa gggggaagta aactggataa aaaaacgaga tattatcaat gtagtagatg 7801 cactgctata aaaaaagctt gaaagaattg acactgtttg tgtgtatata tgtttccggg 7861 tcatgagatt tcaagagatg aagatatcaa aattttgaaa aatactgtga ggatttatgt 7921 aattgatata aattttatat cttaaaaagc agtttgagaa tatcatggac ggttatatac 7981 aattaaaaga tgatatagta cacaaaaaag tctggtaaaa acagactttt ttgtgtacta 8041 taaaataagc agttttattg atgcaaaaaa agacatagag atattgtagc ttatatgatg 8101 aagtgactgg tatatttttt gcttaattat ataaaaaaat catggagaaa tatattatta 8161 tgaaaaaagt aaataaattt aagttgctgg cagcagggct attgatagga gttgcttttt 8221 ggctgttagg atccgatttc tttacattca tgatatggtg ggaaatttta tggattcttg 8281 gattggtatt tatgccgata acggctcaga tattcaaagg ttttgatgat aatggatgga 8341 tgaattcaaa ggttatagca atagtgatat gcggatatgg agtatggatt ttgacttcta 8401 taaaagtggt tcactttacc acattgagtt ctgtcgtaat tactacctta tgtgggggga 8461 gcagtattgc ttatggaata tatggaaaac aaagaaaggt ttttccgtgg aaacatatgg 8521 aacttgttta ttgggaagaa gtgattttct ttgttgtatt tcttttgtgg acatatatgg 8581 caggatttca tccggcagct catggaactg aaaaatatat ggattttggt tttatgaagt 8641 ctatgatgca tagcacaaca cttccgtcag aagatatgtg gtatgctggc aaagctttta 8701 actactatta tggtggtcaa tattttgcgg tgtttcttac gaaacttaca ggaacaaagg 8761 tagagattac atacaatctt atgcgtacca tgatagctgc atttgcgttt gtattgccat 8821 ttagtcttgt gcgccagatg cttaaggata aattaggtaa aaggggaaga gcatggataa 8881 cagattttgg aggtatttta gcaggtttat ctgtatccat gagtggaaac cttcattata 8941 ttatatatgg aaaaattttt acattactgg ggataagaga agattactgg tttccaagca 9001 caacacgatt tataggattt gatccacctg tgacagggga cgagacaatt catgaatttc 9061 cttcatattc ttttgttctt ggggatttac atgcgcatgt gattaatgtg ttttttgttt 9121 tggcagttgg ggattttata tgcatggata aaaagaaatt ccggtaaaag ctggaaacag 9181 aaagagatat ttctgctggg actgttcctt ggaattttcc tgttttcaaa tacatgggat 9241 tttatgattt attatgttgt aatatgtgga acactgtttt ttggaaattt gaagagatat 9301 cttaattcta cagatatgaa accttcagat atgagaaccg gtataaaatg gagcgttgtg 9361 caatggatag aacttctgct gactgctgtg ttgatttcgt taccattcca tttacagttt 9421 aaaagtgtta tggtacaggg aatcggaata gtgaaaattc atacggcgtt ttatcagttt 9481 tgtgtattat gggcttttcc attgcttata tgtggattat ttgtcgtatc tacgctgata 9541 aaaaatagaa attttacaaa taaaaaaacc aggaatttat tttacaaaat taatgtttct 9601 gatttatacg gagttgtact ttctctttgt gcaatgggac taatattgat tccggaaatc 9661 gtttatgtaa gcgatatcta tgaaaaaaca gcaccaagag caaatactat gtttaagctg 9721 acttatcagg catatatact ttttgcactt atgatgtcgt atattttggt attttttgtg 9781 gcagacagaa taaaaatttt gcaagaaact aaattggata atagatatga gaaaaaggta 9841 agattatcaa aagtgcagat aaccgttggg ggaatggcaa taatacttct tatatctacc 9901 tgtggatatt tcataaatgc tacaacaaat tggtttacag gttttcctct gaaaaataaa 9961 taccaaactc tcaatgcaac tgcttatcta gaaaatgcca ttcctgaaga tgcggcagca 10021 atacgatggc tgaataaaaa tataacaggt cagccaactg ttcttgaagc ttgcggcgac 10081 agttataaag actatgacaa ccgggtttct gctatgacag gattgccgac ggtattagga 10141 tggtatgttc atgaatggtt atggcgaaat aatcttgatg aagaaaacaa aagaagaaca 10201 gacgtggaaa ctatttatac ttcaacagat aaaaaagaag tacaggaact gcttgataaa 10261 tatgaggtga attatatttt tattggaagc tgtgaatatc aaaaatatga aggggttaat 10321 gtagcacttt taagttcatt gggagaaata gtttttaaag aggaaaatac aatgattgtg 10381 aagctgtaat aaaacagatt tcaaaaagaa aacagtcaca tatttgagtg aatatcttaa 10441 ttcatcagat gtaagtgact gtttcttttt attgctattt ttgaggtaac tgttttgggc 10501 agatgattac agcatactta tactgtcgct attataacgg ctatatttag cttcctcata 10561 tctgatcatg cagataaaag cgggttcaat atcttttact gtttgtgcaa cattacagaa 10621 atattggaga ggaattgtgg caaaaaacct tataaaaaac acactatgtt ttgaaaaaac 10681 gaatttcgcc aatttatata tgaatttcgc tgtttcataa aattttgcga cgaatgtgtt 10741 atcatttaaa tataagtaag aagaactgaa atgtatctga agaaaggaga agtatcaaat 10801 gaaacatagc agaagcaaaa acgcagtgtt attgatgatt atctttattt gtagtatttg 10861 ttcgaataat gtgtgggctc gtgaaacagg gacaatggat caactggaaa aggagaatct 10921 ggatgatgta gataaaatga ataaagggcg tgtgaaaaaa cgagagtttt ttcatgcgtc 10981 cttttgctta tggatgtaat agtagttata ttacataaaa aagggtatag ttccccttac 11041 cccataagaa tgctattatg aaatcctatg cggcagttgc accttttttc tgtttgttgt 11101 gatatttata aagattgtgt ccgatagaaa caagaaatac ttcgagcagt acagatttta 11161 ttcctcttcg gacaattctt ttgtaccagc gatcgttttt catgatatca aaagtacctt 11221 ctgcctggat ggatctattc atcctcagaa gtgctccctg gatactttcg agattttcta 11281 tcacttcctg atgcatcgct gtaagttcgc ggttgatccg aacagtacgg tttttatctg 11341 tctttttaca ttgttctgcg tatggacagc tggagcaatc ttcacactga tacacttctt 11401 cctgacgccc atacttgttt ccctttacgt ttttttgata ctgaaggtaa aatcttttcc 11461 cgtttgggca acgcataatc ccgtctttcc cgattggaaa atttactgca cgaaatggat 11521 cttcatgata cttcttgtca gtagtctctt tcttgaacat agggaacttc atatattttt 11581 tcattccatg ctgctcacag aagatgtaat tattgtaaga accatatccg gcatctgcca 11641 ctgggtattt cggataaaag ccatatgtcg tataaaactt gttcatcaat ggaataaaac 11701 aatccatatc tgagcgatac tgatttacat cgacaacagc aatgtactca tctgcaacac 11761 cgacctgtac attataggct ggaagcaact ggtcatttcc catgtagtct ttcttgattc 11821 gcataaaagt ggccgaatag tctgtttttg agtagctgtt gcgctcttct ccgcagatct 11881 ttattttttc tacatattct tccaacttgg ttgtatactc cctgagtttt tcataatgac 11941 gctgctgcgt agttttacga tgtcctctac catgaacaaa tatcgtttca tcaatctgcc 12001 aggcttcagc atactgctcg gcagcttctt ttaaatactc tggtgcatac tcactattga 12061 tacaaagctt tatccctgta catgacagct cttcattgat ttccttaaag agttcagtaa 12121 tcttatcaaa gagccggtat ctggattttt ctgtggcttt tttccacacc caggaatatt 12181 tatttgcatt tgcttcaaac ttggaaccat cgatgtatag atgttggaga tccacatgtt 12241 ctgtctcgaa gatttttttg tttatgtctc gaaatatttc ttcaatggaa tcagcaagca 12301 cctcattaat gaagtagccg aaggtacgat aagaaggggt ttgatggtcc ataagataca 12361 taaagcggag attgacttta cactgatcct ccagctcacg taacgatata tagccattcg 12421 ccataaatcc aaacaaaact gtcttcagca tactgaccgg ggcatatcta aatcttcctg 12481 tataatgttg cggaatattt ttcagatatt tctccagttc gatttctccc ataaatctgt 12541 caaaagtcag cactggatca cagatgtcca gataatcttg aattagcatt ggcaaaactg 12601 cctgttttgg gttagaataa attatgttat taattttttt cacaagttaa ttataacaga 12661 aagaaagacc ttgagttcat tataaactct tggtctttct tttttcagga ctattctttt 12721 ttcacagccc ctttcattga ttaagaatta acgatatcat caatcttctt aagttcttca 12781 tctgaaaaat cagtatgtcc gattatcttg atattatcaa gaatctgctc aggttttgaa 12841 gctccaatca ggacacttgt tactttatca tcttttagaa tccagctaag agccatctcg 12901 gcaagcgtct gtcctctttc catagcaatt tcgttaagtg cctgaatctg ggaaagcttt 12961 tctgatgtaa gtgcagtctc attaagaaat cgtccgtcag tggcaattct gctatcagca 13021 gggataccat tgaggtagcg cttcgtaaga agttcctgtg cgagaggaga gaaagctatg 13081 ataccttttc caagctcata ggcagtgtcc ttaagcccgt tattctcaat tgttctgtca 13141 aaaatagaat aacggttttg gttgattacg aaaggacatt tcaaataggt taggatttct 13201 gtagcctttt taagtgtggg accatcataa tttgaaagac ctacataaag ggcttttcca 13261 cttcgaacga tagagtcaag agcacccata gtctcctcaa gtggtgtctc aggatccatt 13321 ctgtgatgat agaagatatc gacataatca agtccaagtc gcttaagact ctggtccagg 13381 cttgcaataa ggtacttgcg gcttccccaa ttgccataag gtccttacca catatcaaat 13441 ccggcctttg tgctgatgag catttcatct cggtatggat gaagttcttc cctgaaaagc 13501 ttgccgaaat tgcgttctgc actgccataa gcaggcccat aattattggc aaggtcaaaa 13561 tgagtgattc cattgtcaaa agcggtaaag cacatctgct tcatattttc gtagacactt 13621 gtatcaccaa aattgtgcca gagtccaagt gaaacaacag gcagcttcaa gccactttta 13681 ccgcagcggt tgtaaactat tgcgtcgtat cttttttgtc tgcaatgtac atgtgtatat 13741 acctccatga ttatatcttt ctgctacact taggatatca tattttttct tcaattgcat 13801 ccagctcttc atttcatcct ctgttttcgc tgtatacgtt actgttcaca cgatgtgcga 13861 ccagcaacgc atctcgccat tttaaatcgc ctttggcgat ggggcgagat gcattcaagc 13921 caaaacatgc atcctccgtg tcaatcagcg aagtgattga cacgggagtg aacagtaacc 13981 tgtatgctac tgcaatttct ccaacaattc cagatgaagt ttctgcacct taatcttttg 14041 tttttgtata ttcactcttt gagtggactt tcctccttcg attttcttta aagctttatg 14101 cttcataaac tcttctttta tatagttttt tcaaaacaac tatagtaata tagagttatc 14161 acaatcttag cttcctacta ttcaacggtt ccttttcgcc atatccagtg gggtgggtaa 14221 agatgaccca ataagtgaat gtaattgaag aaatgtaagc gcaccatagt gcatatatag 14281 acattattat agtaatttga gataattacc tcaacaatta atacttgtca a //