LOCUS gnlProkkaEOGDNDGO_81 14322 bp DNA linear UNK 01-JAN-1980 DEFINITION gnl|Prokka|EOGDNDGO_81. ACCESSION gnlProkkaEOGDNDGO_81 VERSION gnlProkkaEOGDNDGO_81 KEYWORDS . SOURCE ORGANISM . COMMENT ##antiSMASH-Data-START## Version :: 7.1.0 Run date :: 2024-12-01 00:26:28 Original ID :: gnl|Prokka|EOGDNDGO_81 NOTE: This is a single region extracted from a larger record! Orig. start :: 0 Orig. end :: 14322 ##antiSMASH-Data-END## FEATURES Location/Qualifiers protocluster 1..14322 /aStool="rule-based-clusters" /category="RiPP" /contig_edge="True" /core_location="[1691:4322]" /cutoff="20000" /detection_rule="cds(LANC_like and DUF4135)" /neighbourhood="10000" /product="lanthipeptide-class-ii" /protocluster_number="1" /tool="antismash" proto_core 1692..4322 /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="cds(LANC_like and DUF4135)" /neighbourhood="10000" /product="lanthipeptide-class-ii" /protocluster_number="1" cand_cluster 1..14322 /candidate_cluster_number="1" /contig_edge="True" /detection_rules="cds(LANC_like and DUF4135)" /kind="single" /product="lanthipeptide-class-ii" /protoclusters="1" /tool="antismash" region 1..14322 /candidate_cluster_numbers="1" /contig_edge="True" /product="lanthipeptide-class-ii" /region_number="1" /rules="cds(LANC_like and DUF4135)" /tool="antismash" CDS 3..158 /locus_tag="ctg81_1" /transl_table=11 /translation="MFSNKRDRTQLAVGVSKPYTYILGGDLKYVDGIIIWGGNVYGNWG WGVDVW" CDS 315..1553 /locus_tag="ctg81_2" /transl_table=11 /translation="MISDAILYKYRDFFRINKKTEKIILFSYISIMLTWQYWVSYVSFG IIAIANLYLPFFLLLFYKCDFIQAYLWEVLYLVNIGLAKILYIYIIGMIKHRRIENFLF SKSVHFYAGVVYLLIFYVLFLIIQKNFCVEKWLKDLLTDCKKMILFVALSECSILYFLL TMNWGYIENRELIISFGVISGIALILLFVLARFWAKSIYTEKNILEVRNNVIASQYEEL NESYKKYRCLIHDERHMMDYIEECIGTGNFSEAQKIIKKSRNKFSERYYWTGITVLDNV ISIEKRKMDNMNIEFHIETDVTDIVMEDIDIIILLENLFDNAIEAVEKCANKKEIKFSI KNINSMLVLKLWNSSCKKPKVKKERFVTDKHDSKGHGWGLESVKYIVKKYDGIIEFEYT EMFFQTVIMIEGE" CDS 1556..1699 /locus_tag="ctg81_3" /transl_table=11 /translation="MDENIKYELAEAEKLEVIDNAGVAENEKKSIVTVLLSLSCCGHIM NA" CDS 1692..4322 /gene_functions="biosynthetic (rule-based-clusters) lanthipeptide-class-ii: DUF4135" /gene_functions="biosynthetic (rule-based-clusters) lanthipeptide-class-ii: LANC_like" /gene_functions="biosynthetic-additional (smcogs) SMCOG1070:lanthionine synthetase C family protein (Score: 839.8; E-value: 5.1e-254)" /gene_kind="biosynthetic" /locus_tag="ctg81_4" /sec_met_domain="DUF4135 (E-value: 7.3e-95, bitscore: 311.0, seeds: 79, tool: rule-based-clusters)" /sec_met_domain="LANC_like (E-value: 4.3e-58, bitscore: 189.5, seeds: 47, tool: rule-based-clusters)" /transl_table=11 /translation="MLENICIRILILDISEKKSNHELYGFTVHEEYNFYIKHFWKNESY KCDLAIRYAEGSRLQKLKEKYFVILQNEINEKINIDKDMISKKFHENMNEFQMLNKDQG DIHKNGRSVSKIEFDNGSILYYKPHSLDKDIKYQQLYKYLCEKAGISCREVRCLSRQTY GWEENIENKSCNTKEEIERYYFRLGIHLFLGYALGATDLHGENIVAYGEHPVIIDMETY PGYITKNSGSSTEEKAEIKIREKIMTSVLNTGILPVLTWGTGNNRVLMSAVNMHGKIRT PFKMPVVKDDKTSNIHIEYEQVEFEIKECIVRLNGEVVNSEEYTGEIIRGFRMAYTEIL QNQKLRNMLKTFFQGKSRVILRHTQQYYMYLFASFHPDYMKDRKQREELLQVLHKKGET QLQKELRDYEIQSLLELDIPYFEIDGNSRSIFDGNGKEYQGYLPCTPYESWIEHMKQLS CQDMEQQCDYIRLSMGLLNHGYIGEKNPRWADENTCIHQIAEWICRTAVIDGADIGWAG LHFWDNGYWSLKPCGMYLYDGIAGIVLFLAKYLDRYQDSSCRQDVEKIYKLAIEKLEKY TDLRCEQNEVPEPLATGLYDGESSIVYVYLILYEITGQEKWIKNAQKHFEIVAKLLPKD ENMDYLSGNAGAIVAAMKLYQLTGEIEYCTAAVETEKDLWKKGQRMEVGYGWKLKNLKY PLSGLSHGNSGFLMAYVELYKMTYDQEYLKKIKLLLSYEDILYSEDLKNWIDLRDPDGR KTMRGWCHGAPGILLSRMSIMDILPDDKQIKKDILRAVSTLFHNEREKKICLCHGMTGN LLIMKKYLEKNPDDDLRQKYERQFSNLKEQLQDMRSLMVTETLNPAFMNGITGVGMAMM LLNMD" CDS complement(4343..4873) /locus_tag="ctg81_5" /transl_table=11 /translation="MKSLLQLIHDYHSGVKNAGEEILKRMEPLIKSYASRIHCMERDDA TQELYLTLLNTLPYLNGKNFSEGECVRYMQTAIENRYRALCRYHLSEPEREDFDTCSLT LQADNPFDETLYDITTYIESFPVQSMEYKILSLFFYQYKTDSEIASILHVSRQYINRQK KKLLKTYFFRHPD" CDS 5092..5322 /locus_tag="ctg81_6" /transl_table=11 /translation="MESTVMETAISQGIWAVLAVFLLIYIVKSNEQRDAKQEEREKNYQ TVIENLTEKFQILNQVQNDLKEIKDNLLNKN" CDS 5528..7642 /locus_tag="ctg81_7" /transl_table=11 /translation="MKEYKVITALFLSAVMLGTAPLTVWGAESFSTGESFSDGTENIPD IVTDSALSGESSERDYELSIETGTDVELTESDFYDPEFRVEKYVKVRNSGKKETRVRVD ASGLKNFEVDDQMAKWSEDYEEQDSKRLLKPGETLDFFVLPKQEYGTYDETFDFLADDG SRYPVHITMNREKNPTEKKSLEITEKSSESFPIMHWGYKTLPEARIYVLKNFTDMDMEL SFDYSKDCSVSLCGNTSLAPGESTELSLCPQMGLPVGEHDLGVTVTAKTATGETITKKI WDSFRVDSRTFQGLVDTIEPVTGITNGVEKTADALHLPSVLKVYGAEVDGEKTTFSADV KWDVENCAYNPKNTASQSFTVNGQLELREGENNEELDTSVKIKVQVDAYKGLNRPVIDS TWTRVITNYAELSLRDTSNEADGYFFVAAESQKELEKENYIAQVKVAKSELNHYPKLKY IPEGTHYLYCRAYKEESGHTEKYGEWSEGFLLKVNIKTPNAPVVQKLQVKKNDVKIILG SNTEELDGYDVVAARSKDGDEPSDYIKVQCKYSGNSKELILKGVPKGNWYIGVHGYKYL DGSNKKVLSKWAEVQKVTVKTSLVTGKPAVKSAKVSRQGTKRKVTVKFTVPKACDGTDW VLAKKVSQSEDGSYTYVSGYAYTKKNQTKTTVIFKNVKPGVYYLTGRAYVKGYAKNYTK WSEVKKVVVK" CDS complement(7665..7859) /locus_tag="ctg81_8" /transl_table=11 /translation="MPETLTFSVVNWKESDAECTFTVVNSGFGYTTQLQNKYYHTSFGL FILTNNTFFFDIYIYAEKK" CDS 8385..9101 /gene_functions="transport (smcogs) SMCOG1000:ABC transporter ATP-binding protein (Score: 213.6; E-value: 5.3e-65)" /gene_kind="transport" /locus_tag="ctg81_9" /transl_table=11 /translation="MNEMTDAYVKLDKVSKIYGTKEVKIVAVDEISFEIAKGEFVVIVG PSGAGKTTVLNILGGMDQATSGEVLVDGRNIARYNSRQLTGYRRNDIGFVFQFYNLVPN LTALENVELALQICKNPLDAREVLEEVGLKDRLTNFPAQLSGGEQQRVSIARALAKNPK LLLCDEPTGALDYQTGKAILKLLQDMCRERGMTVIVITHNSALTPMADRVIKIKNGKVS RMTMNDHPTPIEEIEW" CDS 9102..12887 /locus_tag="ctg81_10" /transl_table=11 /translation="MMNMKAMHKDFWMEIRKSKARFISIFMIVALGVAFFSGIQASSPD MRFSGDAYYDETNLMDIKVMGTLGLTEDDVAAIKQVDGVENAEGAYGTDVMCGEGEKQK VLHVEAVDQTMNRISVTEGKAPEKSGEIFLDCIFAESNGYKVGDQITLKEGGGSELLKK TDYTVVGLGESPLYISYNRGNSTLGSGEVNGFAYVLPEDFDQEVYTQIYVQAHGAQDLI SYTDAYDSLIERVQERVEGSEAERCQVRYDEIVEEANDKLADARQELEDGKKEANEKLA DARQELEDGKKKLKDGKKEYKDGKKKLADAKKELEDGKARLADAKKELEDGRSQLASAK EQLASGRAQIASAKEQLNAGWAEVSENQAKLDDGKAQLEDGKNQLSAGEKQIADAKTQL TQSQQELDNGKAQIQSGREQIAATRQDLNAKKESCNQGLAQIEQQEAGLAEGEAQLEGA RSQLAALQAQYEQAQASGTYSEEDLAALAAQVSAYQEQVDSQAAQLEASRNQIAAARSE LESGLSQVESGLAQLDAKEAELNQQEAAFPDAQAKIDAGWKEVKAQEKKLEPARKEIQE KEAQLESAQEQIDAAKAKLNSSQAQLEEKEAELASGEAQIRENEGKLASGEKEIADNEQ KLRDGEKEISENEQKLKDSRKDIKKAEKDLEEGKKEYEDGKRDAEKEIADGEKKIQDAR DEIDDISMPEWMVTDRNDLPEYSDYGDNADRMRSIGQVFPVIFFLVAALVSLTTMTRMV EEQRTQIGTMKALGYGKYAIASKYLLYAFLATVGGSILGILIGEKILPLVIINGYGIMY KGMMNNIQIRYEFKFAMIAAGAATVCTVGATIFSCYRALAETPASLMRPPAPKEGKRIL LERIPLFWKHLNFTWKSTLRNLFRYKKRFFMTIFGISGSMALMLVGFGLRDSIMDIARR QYQELQHYTGTIIDDEDATDKERQELDEFLKNNSQIERYTHVQFTKMSVPRNKSNISVY VYVPENLETFNKDVTLQDRKTKEKYKLTDAGTVISEKTATLTGLKVGDTMTITKNGKNY ETKIAAVTENYMGHYIYMTGNVYEQTFGEKPNYSATVFTVKEEYKESESEVGNEILKHP AALSISYTSSLEAQLHRMLGALDTVIVVLIISAGMLAFVVLYNLNNVNITERQRELATL KVLGFYDTEVSAYVYRENVILTLIGVLAGAVFGIFLHRYIIRTVEVDAVMFGRNINPVS FLYCGLLTIGFSMIVNLFMHQKLKKIDMVESLKSVE" CDS 12994..14199 /locus_tag="ctg81_11" /transl_table=11 /translation="MGTANQIEQELMSYISDHKIRNTHSHHLPEQAMVDFDLDKLINNT YLQWQQVTPGTTAESRTAYLEKTRYKSYFVWLQKAIGELYGISEPITAQNWNQISDQIR KAHQNPDFYMDVLKNKCKYQKVIVDTYWNPGSDNGRPELFTPAFRLDLFFLGYKKGLRN HDGVSLEENFGELPDNLQDYVEWVRKWIIQKKSEGCVALKIAMAYERSLHFEKVTREQA ERVFRLQESDITQEDIRCFQDYLFWKICEIAAEVSLPLQCHTGMGQVIDTNILQLNNVI KNNPETKFVLLHCGFPWVDDLFSIVDGYPNLYPDLTWLPILSYTASKRVMHQLIEMSQI DKICWGCDTWTVEESYGSLLAFRFSLCSVLREKIEDGYLSVNNAKDIIDKILFDNAGKI YV" ORIGIN 1 acagctttag caataagagg gatagaaccc aactggctgt tggggtatct aaaccctaca 61 cttatatatt aggaggagat ttaaaatatg tggatggtat tattatatgg ggtggcaacg 121 tttatggaaa ctggggttgg ggtgtggatg tttggtagga tgtttccaga acggaaatcc 181 agttcagaat acagatgggc aaaaatgata cttttaacgc tcttgatttt gacaacatat 241 actatgcata gagcatatgg acaagaatat atatatatga aaaatttttt tttatagttg 301 tttatgctgg agtcatgata tcagatgcta tcttatataa atatagagat tttttcagaa 361 tcaataagaa gaccgaaaaa ataattctgt tttcatatat atcaataatg ttgacgtggc 421 agtattgggt gtcttatgtt tcttttggta ttatagcaat agctaatttg tatcttccat 481 ttttcttgct tttattttat aagtgcgatt tcattcaagc atatttatgg gaagttttat 541 atttagtcaa tattggactt gcaaaaattt tgtatattta cattatagga atgattaaac 601 atagaagaat tgagaatttt ctttttagta aatctgtaca tttttatgct ggtgttgtgt 661 atcttttaat attctatgta ctttttttga ttatacaaaa aaatttttgc gtggagaaat 721 ggttaaagga tttactgaca gactgtaaaa aaatgatttt atttgtagct ttaagcgaat 781 gtagtatttt gtatttttta ttaacaatga actggggata catagaaaac agagaattga 841 taattagttt tggagttata tcgggaattg cattaatatt attatttgtt cttgcacgtt 901 tttgggctaa gagcatatat acagagaaaa atattctgga agttaggaat aatgttatag 961 caagtcagta tgaggaatta aacgaaagtt ataaaaaata cagatgtctg atacatgacg 1021 agagacatat gatggattat atagaagaat gtatagggac gggaaatttc tcagaagcgc 1081 agaaaatcat aaaaaaaagc agaaataaat tcagtgagag gtattactgg acgggcataa 1141 cagtattgga taatgttatt tcaatagaaa aaagaaaaat ggataatatg aatatagaat 1201 ttcatataga aacagatgta acagatatcg ttatggaaga tattgatatt attattttgc 1261 ttgaaaattt atttgacaat gcgatagagg cggttgaaaa atgtgcaaat aagaaagaga 1321 ttaaattcag cataaaaaat ataaatagta tgcttgtatt aaagctatgg aacagtagct 1381 gtaaaaagcc gaaagtgaaa aaagaaagat ttgtgactga taaacatgat tctaaaggtc 1441 atgggtgggg attggaaagt gtaaagtata tagtaaaaaa gtatgatgga attattgagt 1501 ttgaatatac agaaatgttt tttcaaacgg ttattatgat tgaaggagaa taaaaatgga 1561 cgaaaatata aagtatgaat tagcagaagc agagaaatta gaagtaatag ataatgcagg 1621 ggttgctgaa aatgaaaaaa aatcaattgt aacggtattg cttagtctgt catgttgtgg 1681 acatataatg aatgcttgaa aatatttgta ttagaatatt gattttggat atttctgaaa 1741 agaaaagcaa ccatgagttg tatggcttta cagtgcacga agaatataac ttttatataa 1801 aacatttctg gaaaaatgag tcttataaat gtgatttggc aatacgctat gcggaaggaa 1861 gtcgacttca gaaattaaag gaaaaatatt ttgtaatatt acaaaatgag ataaatgaaa 1921 aaatcaatat agataaggat atgataagta aaaaatttca tgaaaatatg aatgaatttc 1981 agatgttgaa taaggatcaa ggagatatac acaaaaatgg tcgcagtgta tcaaagattg 2041 agtttgataa tggcagtata ttgtattaca aacctcacag ccttgacaaa gacataaaat 2101 atcaacaact atacaaatat ttatgcgaaa aagcaggaat atcctgtcgg gaggtgaggt 2161 gcttatccag acagacatat ggatgggaag aaaatataga gaataaatca tgtaacacaa 2221 aagaagaaat agagcgttat tatttcaggc tgggcatcca tctgtttctc gggtatgcat 2281 tgggagcaac agatcttcat ggagaaaata ttgttgcgta tggagaacat ccggtgatta 2341 tagatatgga aacatatccc ggctatatta caaagaatag tggaagtagt acagaagaaa 2401 aagcagaaat caaaataaga gaaaaaatta tgacatccgt gttaaacacg ggtatccttc 2461 ctgttctcac atggggaact ggaaacaata gagttcttat gagtgctgta aatatgcatg 2521 gcaagataag gactccgttt aagatgcctg ttgtcaaaga tgataaaaca tcaaatattc 2581 acatagaata tgaacaggta gaatttgaga taaaagagtg cattgtaagg ttaaatgggg 2641 aggtggttaa ttccgaagaa tatacaggag agattatcag gggatttcgg atggcttata 2701 cagaaatact gcaaaatcag aaactcagaa atatgctgaa aacttttttt cagggaaaat 2761 ccagagtaat tttgcgacat acgcagcaat attatatgta tctgtttgcg tcgttccatc 2821 cggattatat gaaggaccgg aaacaacgag aggaacttct tcaggtattg cataaaaaag 2881 gggaaaccca gttgcagaaa gaattaagag attatgaaat acagagcctg ctggaactgg 2941 atattccata ttttgaaatt gacggaaaca gcagatcaat ttttgatgga aatggaaaag 3001 aatatcaggg atatctgcca tgtacacctt atgaatcatg gatagagcat atgaagcaat 3061 tgagttgtca ggatatggag caacaatgtg attacatacg attgtctatg ggattattaa 3121 atcatgggta tatcggcgaa aaaaatccgc gatgggcaga tgaaaatact tgtatacatc 3181 aaattgcaga gtggatttgc agaacagctg taattgacgg agctgatatt ggatgggctg 3241 gactgcattt ctgggataat ggatattgga gcctgaaacc atgtggtatg tatttatatg 3301 atgggattgc ggggattgtt ttgtttctgg caaaatatct ggaccggtat caggattcgt 3361 catgcaggca agacgtggaa aaaatctata aactggctat tgaaaaatta gaaaaatata 3421 cagatctgcg atgtgaacaa aatgaagtac ctgaaccatt ggcaacagga ctttacgatg 3481 gagagagttc aattgtatat gtttatctga tattatatga gatcacaggt caggaaaaat 3541 ggatcaagaa tgctcagaag cattttgaga tagtagctaa actgcttcca aaggatgaaa 3601 atatggatta tctcagtgga aatgcaggcg caatcgtggc tgccatgaaa ctttatcaat 3661 taactggaga gattgaatat tgtacagctg cggtagaaac tgaaaaagat ttatggaaaa 3721 aaggtcagag aatggaagtg ggatatggat ggaaactgaa aaatctgaaa tatccgctga 3781 gtggactttc tcatggaaac agtggctttt tgatggcgta tgtggaactt tataaaatga 3841 catatgacca ggaatatctg aaaaaaataa aattgttgct ttcctatgag gatatcttat 3901 attcagaaga cttgaaaaac tggatagatc tgcgtgatcc ggacggacga aagacaatgc 3961 gtggatggtg ccatggtgct cctgggattt tacttagccg tatgtcgata atggatattc 4021 tgccagatga taaacagatt aaaaaggata tcctgcgggc agtatccaca ttatttcaca 4081 atgagcgtga gaaaaaaata tgtctgtgcc atggaatgac aggaaatctt ttaattatga 4141 aaaagtatct ggagaagaat ccggatgatg atttaagaca gaaatacgaa aggcagtttt 4201 cgaacctgaa ggaacaattg caagatatga gaagtcttat ggttactgag acattaaatc 4261 ctgcatttat gaatggaata accggagttg gaatggcaat gatgttgctg aacatggatt 4321 agaaaaggca tttacagcct ttctaatcag gatgtctgaa aaaataagtt tttaacagtt 4381 tctttttctg acgattaatg tattgacggg agacatgaag aattgatgca atttcggaat 4441 ctgttttata ctggtagaaa aacagagaca gaattttgta ttccatactt tggacaggaa 4501 agctttcgat atatgtagtt atatcataaa gagtttcatc gaatggatta tctgcctgta 4561 aagtaagaga acacgtatca aagtcttctc tttcaggttc tgacaaatgg tatctgcata 4621 aagctctgta acgattttct atagcggtct gcatatatct gacacattca ccttcggaaa 4681 aatttttgcc gttcaggtaa ggcagtgtat taagcagagt cagatacaat tcctgtgtgg 4741 catcgtcccg ttccatacag tggatgcggg aagcgtagct tttgatcaga ggttccatac 4801 gtttaagaat ttcttcacct gcatttttga caccagaatg ataatcgtga attaactgta 4861 ataatgactt cataagaaac tacctccttt ttggaggaag tagtcagaag tgactaaatc 4921 agaaactgaa aatagaaaaa atatgaattt attgtagaaa aataaaagaa gcgaagtctg 4981 acaacagaag aaataagctt ctaaaaggaa ttgagttgac aaattatgag attttctgtc 5041 tttctcagag gaactgaaat gttttactac tgagaaagga ggtatgaaga tatggaatcc 5101 acggttatgg aaactgcaat atcgcaggga atctgggccg tcctggcagt ttttcttttg 5161 atttacattg taaaatccaa tgaacaaagg gatgcaaagc aggaagaaag ggaaaaaaat 5221 taccagacag tgattgagaa tttgactgaa aaattccaaa ttctaaatca ggttcagaat 5281 gatctgaaag agattaagga taatcttctt aataaaaatt aaataggaaa aagaaataga 5341 agctctctct acaaaatgaa tgtcacagta gggagggctt ttgtcattca ggtaagaaaa 5401 cagattaatt caatatacag gcaaaacact catatccatt agaatacatt ttattccaga 5461 attacagagg tttatataaa tggtgatata ctatgataat aaatattatt gaatggagga 5521 aaaagagatg aaagaataca aggttataac agcacttttt ttgtcagcag taatgctggg 5581 tacagctcca ttaaccgtat ggggagcgga gagtttttcg acaggggaat ctttcagtga 5641 tggaacagaa aatattcctg acatagtaac agattcggct ctgtctggtg aatcttctga 5701 aagagactat gagttaagca tagaaacagg tacggatgta gagcttacag aaagtgattt 5761 ttatgatccg gaatttcgtg tagagaaata tgtgaaagtc agaaattcag gaaaaaaaga 5821 aacaagagtc cgggtagatg cttctggtct taagaatttt gaggtagatg atcagatggc 5881 aaagtggtca gaggattatg aggaacagga ttccaaaaga ctgctgaagc cgggagaaac 5941 tctggatttt tttgtactgc caaagcagga atacggaaca tatgatgaaa cgtttgattt 6001 ccttgcagat gacggaagca gatatccggt tcatatcaca atgaatagag agaagaaccc 6061 aacggaaaag aagagtctgg aaattaccga aaaatcttcc gagagtttcc cgataatgca 6121 ctggggatat aagacacttc cggaagccag aatttatgtt ttgaaaaatt ttacggacat 6181 ggatatggaa ctgtctttcg attatagcaa agactgtagt gtatcattat gcggaaatac 6241 cagtctggca cctggagaga gtacagaact gagcctttgt ccgcagatgg gactgccagt 6301 tggagaacat gatcttggag tgacagtgac tgcgaaaaca gcgacaggag agactataac 6361 aaagaagatt tgggattctt tcagagtaga ttcaaggaca tttcagggac tggtggatac 6421 cattgaacct gtgaccggaa ttaccaatgg cgtagaaaaa actgctgatg ctttacattt 6481 gccatcggtt cttaaagtct atggtgctga agtggatgga gaaaaaacga cattttctgc 6541 cgatgtaaaa tgggatgtgg agaattgtgc atataacccg aaaaatacgg cgtctcaaag 6601 tttcacagtt aacggacaat tggaactgcg tgaaggtgaa aacaatgaag agctggatac 6661 gtctgtaaag ataaaggtac aggtggatgc gtacaagggg ttgaacagac cggtgattga 6721 ttcgacatgg accagagtga tcacgaatta tgcagaactt tctttaagag atacttctaa 6781 tgaagcagac ggatattttt ttgtagcagc agaatctcaa aaggaactgg aaaaagaaaa 6841 ttatatcgca caggtgaagg tcgcaaaatc tgaactgaat cattatccta aactgaaata 6901 tattcctgaa gggacgcatt atctctattg cagggcatat aaagaggaaa gtggtcatac 6961 ggagaaatat ggtgaatggt ctgaaggatt tctgttaaag gtaaatataa agacaccaaa 7021 tgcacctgtg gttcaaaaac tacaggtgaa gaaaaatgac gttaaaatta tccttggcag 7081 taatacagaa gaactggatg gttatgatgt tgttgctgcc agaagtaaag acggggatga 7141 gccatcagat tatataaagg tacaatgcaa atattcagga aacagcaagg aactcattct 7201 aaaaggagta ccgaaaggaa actggtatat tggtgtacat ggctataaat atctggatgg 7261 atcaaataaa aaagtactga gtaagtgggc ggaagttcaa aaagtaacgg taaagacaag 7321 ccttgtaaca ggaaaaccag ctgttaaatc ggcaaaggtt tccagacagg gaacaaaaag 7381 aaaagtaacg gtgaagttta ctgtaccaaa agcctgtgac ggaacggact gggtactggc 7441 aaagaaagta tctcaatccg aagatggaag ttatacatat gtcagcggtt atgcttatac 7501 taagaaaaat cagacgaaaa ctacagtcat ttttaaaaat gtaaaacctg gagtttatta 7561 tcttacagga cgtgcttatg taaaaggata tgcaaaaaat tatacgaaat ggtcagaggt 7621 aaagaaagta gttgtgaagt agaaaagtga tttagaccag aaatttattt tttttctgca 7681 tatatatata tatcaaaaaa gaaggtgttg tttgtcagaa taaataatcc aaaggaagta 7741 tggtagtatt tattctgcaa ctgtgtggta taaccaaaac ctgagtttac gactgtgaat 7801 gtacattctg catcagattc tttccagttt acaacactga aagttaatgt ttctggcata 7861 atttttgtct cctttaaatt ttttgaattt gcaaattcac tatataaaga tgctgctttg 7921 gtgatttgta aaccataagt gtgtatatga gcatgatttt tttctttcat gcggaaatta 7981 ggtaagaata aaaataaaga ttcgaggtca gatgatgcag gtttattccc tttttatatt 8041 ttctgcatca gtttactgta aaataataac gggtaaagaa gatataagat gttctggtac 8101 atacaattaa gaagaaaggg gcatgtgctg tgtatagtca aaatgatgaa ccgcctgaga 8161 tgatcaggcg gttttgaagt atctggattt tttatgaata ttttattttt aattacaggt 8221 ataatgtgtt acaataaata taaccattaa gactaccagg caggtcagaa tttgacctgc 8281 ctgtaaataa atacggaaat aaatcgggtt caaaagaatc gttaataatt gtaacaaaat 8341 aaaattaccg gtatggcaaa aataaaatta caggggaaat gcggatgaat gagatgacag 8401 atgcatatgt aaaactggat aaggtttcca aaatatatgg aaccaaagaa gtaaagatcg 8461 ttgcagtgga tgagatcagc tttgagattg ccaagggaga gtttgtagtg atcgttggtc 8521 ccagcggtgc gggcaagacg acagtgctga acattcttgg gggtatggat caggctacca 8581 gcggagaagt tctggtggat ggaaggaata ttgccagata taacagcagg cagcttaccg 8641 gttatcggag aaatgatatt ggatttgtat tccagttcta taatctggtg cctaatctta 8701 cagcgctgga gaatgtagaa ctggcattgc agatttgtaa aaatccgttg gatgccaggg 8761 aggttctgga ggaagtggga ctgaaggaca gactgaccaa tttcccggca cagctttccg 8821 gcggtgaaca gcagagagtt tccattgcca gggcactggc gaagaatccc aagctgttgt 8881 tgtgtgatga gcccacaggt gcactggact accagacagg taaggcaatc ctgaaacttt 8941 tgcaggatat gtgcagagag cgtggaatga cagtgatcgt cattacccat aactcggcgc 9001 tgacacctat ggcagaccgt gtgatcaaga tcaagaacgg caaggtttcc aggatgacaa 9061 tgaatgacca tcctacaccc atagaggaga tagaatggta ggtgatgaat atgaaagcaa 9121 tgcataaaga tttctggatg gagatacgca agagcaaagc cagatttatt tccatattta 9181 tgatcgttgc tctgggagtt gcgtttttct ccgggataca ggcctcgtca ccggatatgc 9241 gcttctcagg tgatgcctat tatgatgaaa ccaatcttat ggatatcaaa gtaatgggaa 9301 ctctgggact gacggaggat gatgtagctg ccattaagca ggtggacgga gtagagaatg 9361 cagagggcgc ctatggtaca gatgtaatgt gtggagaagg cgagaagcag aaggtacttc 9421 atgtggaagc tgtggatcaa accatgaatc ggatctcagt gacagaggga aaagctccgg 9481 aaaaaagcgg agagattttc cttgactgta tttttgctga gagcaatgga tataaggtgg 9541 gtgatcagat taccctgaaa gagggcggag gcagcgaact gctgaaaaag acagattaca 9601 cagttgtggg tttaggtgag agtccgcttt acatatccta taaccgggga aactctactc 9661 ttggttccgg tgaggttaat ggatttgcct atgtgctccc tgaggatttt gaccaggagg 9721 tttatacaca gatctatgtg caggctcatg gggcacagga tctgatcagc tatacagatg 9781 cttatgattc cctgatagag cgagtgcagg agcgagtgga ggggagtgag gcagaacggt 9841 gtcaggtcag atatgatgag attgtagagg aagccaatga caagcttgca gatgccagac 9901 aggaacttga agacggaaag aaggaagcta atgagaagct tgcggatgcc agacaggaac 9961 tggaggacgg caaaaagaag ttaaaagacg gaaagaagga atataaggat ggcaagaaaa 10021 agcttgcaga cgcaaaaaag gaactggagg acggaaaagc ccggcttgca gatgcaaaga 10081 aggaattaga ggatggcaga tcccagcttg ccagtgcgaa agagcagctt gccagtggca 10141 gagcacagat cgcatctgca aaggaacagc tgaatgcagg atgggcggag gtttcagaga 10201 accaggcaaa gcttgatgat ggaaaagcac agcttgagga tggcaagaat cagttaagcg 10261 ccggtgagaa gcagattgcg gatgcaaaga cgcagcttac ccagagccag caggaacttg 10321 acaatggaaa ggcgcagatt cagtcaggca gagagcagat tgcagcaacc agacaggact 10381 taaatgccaa aaaggaaagc tgcaatcagg gacttgcgca gattgagcag caggaggccg 10441 gacttgcaga aggagaggct cagcttgagg gtgccagaag tcagcttgca gcattgcagg 10501 cacagtatga gcaggcacaa gcttcaggca catattccga ggaagacctg gcggctctgg 10561 cagcacaggt ttccgcttat caggagcagg tggacagtca ggcagcccag ctggaagcat 10621 ccagaaacca gatcgcagca gcaagaagtg aactggagag tggtttaagc caggtggaga 10681 gcggactggc ccagcttgat gcaaaggaag cagaactgaa ccagcaggag gccgcatttc 10741 ccgatgccca ggcaaagatt gatgcaggat ggaaagaggt gaaggctcag gagaagaagc 10801 tggaaccagc cagaaaagag attcaggaaa aagaagccca gcttgagtca gcacaggaac 10861 agatagatgc tgcaaaagca aaactaaatt ccagccaggc gcagttagag gagaaagagg 10921 cagaacttgc ttcaggagaa gcacagatcc gggagaatga agggaagctt gcttccggcg 10981 agaaagagat tgccgacaat gaacagaagc tgagggatgg agagaaggaa atctcagaga 11041 acgaacagaa gctgaaggat tccagaaagg acatcaagaa agctgagaag gatctggaag 11101 aaggtaaaaa agaatacgaa gacggcaaga gggatgcaga gaaagaaatt gcagacggtg 11161 agaaaaagat tcaggatgcc cgggatgaga tcgatgatat cagtatgccg gaatggatgg 11221 taacggaccg caatgatctg ccggaatatt cagattatgg ggataatgca gacagaatga 11281 gaagtatcgg acaggttttc cctgttatct ttttcctggt ggctgcactg gtaagtctga 11341 ctaccatgac acgaatggtg gaagaacaga gaacccagat cggtacaatg aaggcgttgg 11401 gatatggcaa gtatgcgatt gcatccaaat atctgctgta tgcctttctt gccacagtgg 11461 gaggcagtat tctgggaatt ctgatcggag agaagatcct gcctttggtt attattaacg 11521 ggtatggcat tatgtacaag ggcatgatga acaatatcca gatccgttat gagtttaaat 11581 ttgcaatgat agcagcaggt gcggcaactg tgtgtaccgt cggagccacc attttctcct 11641 gttacagggc actggcggaa actccggcat cactgatgcg tcctcctgct cccaaagagg 11701 gtaagagaat cctgctggaa cgtatcccgc ttttctggaa acatctgaat tttacatgga 11761 aatctacact gagaaatctt ttccgatata aaaaacgttt ctttatgacg attttcggta 11821 tttcaggaag tatggcgctg atgctggtag gctttggact cagggattcc attatggata 11881 ttgccagacg gcagtatcag gaacttcagc attacacagg aacgatcatt gatgatgagg 11941 atgctacaga taaggagaga caggaactgg atgagtttct gaaaaataac agtcagatcg 12001 agagatatac tcatgtgcag tttaccaaga tgagtgttcc cagaaataaa tccaatatca 12061 gcgtatatgt ttatgtgcct gagaatcttg agacctttaa taaggatgta acgcttcagg 12121 acagaaagac aaaagagaag tataagctga cggatgcagg tacagtgatc agtgagaaga 12181 cggcaaccct gacaggactg aaagtcgggg ataccatgac catcacaaag aatggaaaaa 12241 attatgagac aaagatcgca gcagtgacag agaattacat gggacattat atttatatga 12301 caggaaatgt ctatgaacag accttcgggg agaagccgaa ctattctgca actgtgttca 12361 cggtaaaaga ggagtacaaa gaatcagaat ctgaggtggg aaatgaaatc ctgaagcacc 12421 cggctgcatt aagcatcagc tataccagca gtctggaggc tcagcttcac agaatgctgg 12481 gggcattgga tacggtaatt gtagtgctga tcatttctgc gggaatgctt gctttcgtgg 12541 ttctgtataa tctgaacaat gtcaatatca cggagcgcca gagagaactg gcaactctga 12601 aggtgctggg attctatgat actgaggttt ctgcctatgt gtacagggag aatgttatcc 12661 ttactctcat cggcgtgctg gcaggagctg tattcggaat ctttttgcac aggtatatta 12721 tccgtactgt ggaagtggat gcggttatgt tcggaagaaa tattaatcct gtcagtttcc 12781 tgtactgcgg actgctgaca attggattct ccatgatcgt aaatctgttt atgcatcaga 12841 aattaaagaa gattgatatg gtagaatccc tgaaaagtgt ggaataaacg atctgtcgct 12901 ttattgcgga aaagaagaaa ttgtttttct gtggttttta aatatgtagt caaacggata 12961 gaatggataa gaggaagaaa ggggaatatt atcatgggaa cagcaaatca gatagagcag 13021 gaattaatga gctatatatc cgatcataaa atcaggaaca cgcattcaca tcatctgccg 13081 gaacaggcga tggtggattt tgatctggat aagctgataa ataatacgta tttacaatgg 13141 cagcaggtaa ctccggggac aacagcagaa agcagaactg catatctgga aaaaacacga 13201 tataaatctt attttgtctg gcttcaaaag gcaatcgggg agttgtatgg aatatcggag 13261 ccgatcacag ctcagaactg gaatcagatt tcagatcaga tcagaaaagc gcatcaaaat 13321 cccgactttt acatggatgt gctgaaaaat aagtgtaagt atcaaaaagt aatcgtagat 13381 acctactgga atccgggctc tgacaatgga agaccggaac tgtttacgcc tgcttttcga 13441 ctggatctgt tctttttggg ctataaaaaa ggacttcgca atcatgacgg tgtatcactg 13501 gaagagaact tcggtgagct accggacaat ttacaggatt atgtggagtg ggtcagaaag 13561 tggatcatac aaaaaaagag tgagggctgt gtggccttaa aaatagcgat ggcctacgag 13621 cgtagtcttc attttgaaaa agtgacgcgg gagcaggctg aaagggtatt ccgtttacaa 13681 gagtcggata taacccagga ggatatcaga tgttttcagg actatttgtt ctggaaaata 13741 tgtgaaattg cggcggaagt gtcacttcca ttgcagtgcc atacaggaat gggacaagtc 13801 atagatacga atatattgca gttgaacaat gtgataaaaa ataatccgga aacaaaattc 13861 gtactgctgc attgcggctt tccatgggta gatgatctct tttccatagt agacggatat 13921 ccgaatctgt atccggatct gacctggctt ccaatcttat cctacactgc atcaaaacgt 13981 gtaatgcatc agctgatcga gatgtcccag attgataaaa tctgctgggg atgtgataca 14041 tggacagtag aggaaagtta tggctccctt cttgcattcc gtttttcact gtgcagtgtt 14101 ctgagagaaa aaatagagga cggatatctt tccgtaaata atgcaaagga tattattgat 14161 aaaattttgt tcgacaatgc gggaaaaata tacgtatgac accagaaagg aggcggaagt 14221 atccatgaat tcaacaattt ccattggaat gcaggatttt ggtaagctga tcagaagtgg 14281 tgtgttttat gtggataaga cgtcttttat caaagaatgg tg //