LOCUS       gnlProkkaMDLEHPFK_117  14646 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDLEHPFK_117.
ACCESSION   gnlProkkaMDLEHPFK_117
VERSION     gnlProkkaMDLEHPFK_117
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:12:56
            Original ID  :: gnl|Prokka|MDLEHPFK_117
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14646
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14646
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3926:4646]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3927..4646
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..14646
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14646
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             complement(133..1776)
                     /locus_tag="ctg117_1"
                     /transl_table=11
                     /translation="MTIKYTKEQLNKFDKDLLIELFLGMQGQMEELSRQTQALNDRMQL
                     MMEQMVLFQKNRFGRSSEKMADSEQIRFMEVDGTIVFFNEAEAVCDLDAPEPDDLELKA
                     PKKKKQPGKKAADIAGLTVKRIDHYLKEEELTAEFGENGWKQLPDAISRCYQFIPASVV
                     IEEHHIGVYSSKLDEHMIKAPHPRNLLHGSLVSPSLAAAVINGKYVNAVPLYRLEKEFE
                     RYGLAITRQNMANWMIRLGEEYLGTMYDYLHKLLYDYHVIQADETPVLVNKDGRPAGSQ
                     SYMWVYRSGFMYRDRQIILYEYQKTRNASHPREFLRDYTGVCVTDGYQVYHTLEKERED
                     LKIAGCWVHCRRRFNDALEVIPKAHRKESILHLIMKQIQAIYREEGKLSDFSTEDRLMQ
                     RQLVVKPLVDAFFAYLKQNEPKIPKNGKIREAFTYALNQESYLKVFLEDGDVPIDNNAS
                     ERAIRGFCIGKKNWEMIDTVNGANSSAIIYSIAETAKANNLKPFDYFEYLLTEIPKHVD
                     DKNTDFLAELLPWSDMLPENIRKPQKTSGK"
     CDS             complement(2056..2424)
                     /locus_tag="ctg117_2"
                     /transl_table=11
                     /translation="MLNDADASGFKKVYLAMGFTDLRRGIDGLATIVRFQFKLDPYDKN
                     TLFLFCGRRCDRIKALLWEGDGFLLMYKRLDNGAFRWPRSADEAMAITDDQYRMLMQGL
                     EIVARHPISELKETPRIM"
     CDS             complement(2414..2815)
                     /locus_tag="ctg117_3"
                     /transl_table=11
                     /translation="MATQTSLVAQQVRIRQWAEQIRNCQNRPKGMDVETWCTQNNLTKA
                     NYYYRLRRVRQICLDQMQDTETTAFVELPAPAPDPKKTDTPKESGTCISAGTLPMIRIK
                     NTRGLSAEIFSGTSPEMLCHLIKAFTHAE"
     CDS             complement(3171..3881)
                     /locus_tag="ctg117_4"
                     /transl_table=11
                     /translation="MKIAICDDEKPFLDKLYQILQEIRMELNIPISIIKFIDGKELLNY
                     FEVHKDIDVFILDILMNPINGYDVARKIRKMDNKVKLVFLTSIKNYAIAGYNIRLEKYI
                     LKPVSKKVMSKVILEIYNQLYRNGKFLIVKNVEGLFKLYFEDIYFIETEDKHVLIHTKD
                     SSVKCYHCLKLLEDKLDTNFYRCHASFIVNLLHIDTYERLEIKLENNFHIPVSKHRKSG
                     FTEKLLDFYARYME"
     CDS             complement(3927..4079)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_5"
                     /sec_met_domain="TIGR04223 (E-value: 1.5e-10, bitscore:
                     32.3, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNWKKSLFKMMGKMSMFVAVYTVALGYPHCLIILHQPQVPEKLK
                     KMREG"
     CDS             complement(4089..4646)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg117_6"
                     /sec_met_domain="AgrB (E-value: 2.3e-34, bitscore: 109.6,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKRISMLLAQKIVLENNEKDNEDIYAYGLEIIINSLISIISVLA
                     IGILQHNFWYTVIYLTTYCSIRLYAGGYHAKNNFYCILIFVLAYMCSPIWNVLYCKFVT
                     AFITLCIINLVVISWAPVDSLQNPILDSERLLLKKKAIGLTVIVSVLILCNVILRFSSH
                     ISGASAALTYIGIVVAVGKLKD"
     CDS             complement(4650..5960)
                     /locus_tag="ctg117_7"
                     /transl_table=11
                     /translation="MIDLVSTFVGTFFDICLLIYYIKDRAVKVNKMVFFVCFISCTFIN
                     VLINILPFSFLIKLILKIVILIFWIYIVYEDIYILDSLRITVIFLMLLGASEILILPIV
                     MLCTGIYDIDLFYDNKFIWFYSYISSKLLSMILISLSMKVMKKHEIKMSKSELFITYTP
                     LLNTFLIFIFFANFLVDIENVRYHDIMAAFILISIVLCVFTYTHINVFQHYMEIKKREY
                     DNEVIVQKAKHEYELYKSKLEKLKELQIIQHDLKNHILVAQGEKESLYYDELLTRIEKN
                     NNIDSGNEIIDMLLEEKSKIAMSKNIKIDIQIEKGILKFINDIDGCSLFGNLMDNSIEA
                     CEKVSTQKTEILIKVKRLNKFLLIYVENDMEKKLIKRKHNVLLTTKVSVKEHGIGTKSI
                     KMIVNKYDGEYKYEINNGKFITRILMPMNNFKLDGVD"
     CDS             complement(5953..6138)
                     /locus_tag="ctg117_8"
                     /transl_table=11
                     /translation="MFKVNKNLAKCNVARTIRFTENIYGDLLRISESEQVSFNQLVLQC
                     CQYAIDEYADKGDKND"
     CDS             complement(6573..7142)
                     /locus_tag="ctg117_9"
                     /transl_table=11
                     /translation="MITIQNLKEQMKGYTLEITDLNILTGDIFGIYIDDLECKERLINL
                     ISLLEIPSKGNIKIGGIDTNDKRYQTYLRRKIGVITKNLLLIDNYNVELNIVLPIDLSA
                     QTKNNERLIAIAKDFNLENSLKAYPKELDWVKQVSVLFARCIYNMYELIIADIDMLNEE
                     QLLTLLNLCKTHKYTLIFFTMHVEFL"
     CDS             complement(7084..8988)
                     /locus_tag="ctg117_10"
                     /transl_table=11
                     /translation="MHCLKVFWSNLLEAFKFEILFKIICLIIILPIIKFIIDKYLWING
                     YNISFNSDIISRFFTWPSLIILVIIIMVFTICIFFEISVNIIIGIATYNNNRIKVFTVV
                     CIAVDITKKIIRKNIIGIAAFYVGVLPFLHFVYINSLVPKLAIPNFVIGEIDRMSLGIV
                     LKCLLIISKVIIFASTAFIPILMVVNDIGFYNACKKSFVIAKSIFAKKRLQFLGVISVF
                     LLVQYTKFGNLKLKSSDFSIYTVKWIIKNTSFRNAVFEDIILNAILIVFNMVLLLFFIK
                     ISNGLIDLPSDYKASYKGIDLTLGQKSLKFFGGMGKKLYNNSFILKYRMQIKLGIIGIL
                     FVILFVYLQSPPQVHEPWVIGHRGCKYEIENTVNAVLAADKFKADYAEIDIQLTKDKVP
                     IVIHDSNLLRLCDKFSNVENLTLNQIKQLNLSSNNKVDKIPTLEEVIKAAKSSVNKIGL
                     LIELKGESHELVEKVVDIVEKNSFGHKCIFMSLNYKFVIELQKLKPEWWIGYCVFGSVG
                     ELNQSILELNIDFLAIEEGQANYNFISKARDYWLPVYIWTANNKKDIKEYLEMGASGII
                     TDQPDKIRGEVDRFIDNYKGSYQFFNSYPDLSNGGMENMYDYYTEPERANEGIYIGNY"
     CDS             complement(9051..9194)
                     /locus_tag="ctg117_11"
                     /transl_table=11
                     /translation="MNDENVKENEQKEIEVELYEYCASTKKRCLNDCIEPWRGTPVLSD
                     VN"
     CDS             complement(9206..9340)
                     /locus_tag="ctg117_12"
                     /transl_table=11
                     /translation="MEKTNDFEEEVDTIDGYSTCSTTKQQCLTDCVPPFEAPVLSDVN"
     CDS             complement(9384..11885)
                     /locus_tag="ctg117_13"
                     /transl_table=11
                     /translation="MKISLTENDILRHLSFRKLKLNPLKNIILVISIFLTTVLFTSVFT
                     IALSLNKSIEISALRQVGGEADISFKYLTYEAEKKIASNDNKNIKKVGKSIILGLANNS
                     SLIERQCEMRYADDEYAKMSFDYPTKGQMPKEKREIATDTLVLDMLGIPHKLGEKVELE
                     FVDINGNPHEDKFVLCGFWEADKIAPASQIWMSKEYLKGYWSSDNKELNGLRMLSIKTD
                     NKYDSKKIAKEILEEERLQNIDFNTSGAYSEISSTEKINIMLALGGMFFFIILSGYLII
                     SNIYQISIVKEINFYGSLKLIGATSRQIKKLLYVQTVPVAIVGVSLGLIMGYLIGYLLL
                     PPILDSSLGRESLNMSMSPIIFIGSILCTIFTVWISSRKALKVASKVSPINASKYFDSN
                     FVKHKNRKYINISRLSWINLFRHKKRVIMVICSLVMSTVLFESTYLIGNSFDLDKYIET
                     KMVSDYSLSDYCVSSYTRKYEPNNTVTLDMLSQIKAINSNAQISNMYFDIDTVSFDDQD
                     VYDKVIRKNKNSNKEYEEEVEKLISKKIMQAKVYGIDADIINKCAIFSGEFSPKEFEHE
                     NYVLAIGYDDDSDYEVIYEIGDKVKIKNSIYTVMGYVDIPDTVLGSIPEESAPLTQGFV
                     MSTNSFMKLHGEPSIYQSFINVSDNKNRKIQKLLNEFQKDNANLDVKSKQTYAREFQMQ
                     IFSQTALGYMMSIIVGLIGIMNYINTAASSIISRRHEFVILHSIGMTKRQLKNMLLLEN
                     IYIVSLVSIFSIMLSSVLGRTFVKSIIETSWCSSYRFAVWPLFAVLLLYFGISIIMPLL
                     LIKNQEGESIVFRMKQLTDSY"
     CDS             complement(11875..12567)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 204.6; E-value:
                     3e-62)"
                     /gene_kind="transport"
                     /locus_tag="ctg117_14"
                     /transl_table=11
                     /translation="MYRVYLNNVCKIYGKGNNQVKALDNVSVRIEDNKFTAIIGKSGSG
                     KSTLINMISGLDYPDKGTVTVGDIEISSLSENEKIIFRRKNIGVIFQNYNLLPELNVYE
                     NIILPIALDKKKIDEYFLSKVLLQLDINEKIYEYPNNLSGGEQQRIAIARALLSKPQII
                     IADEPTGNLDGDNSANVIHLLKTICKEFKQTVIIVTHDLEIAYGADAVIKLKDGKIVDN
                     IRSNGNEN"
     CDS             complement(12586..13095)
                     /locus_tag="ctg117_15"
                     /transl_table=11
                     /translation="MLSNNSIAVFWHRDSCTMNLVLSYLKKKNFKPIVVVITADPRGDY
                     IEAAIKKFGAESIRIDFNAFDVKEYKNLKELANKDNIIAIAMDGPLGPFKEPKRLPFYL
                     GSCSKKKIVGISVEYEKVIRIAHRWDKYVIPLPCSHIRINFIDFERVNSKTEYLLIKSA
                     IKLKMK"
     CDS             complement(13130..14410)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 149.8;
                     E-value: 2.1e-45)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg117_16"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.1e-38,
                     bitscore: 123.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIAMLTNNYKPFIGGVPISIERLANGLEMLGHEVYIFAPTYEGQ
                     EAEVNVIRYKSFSQKLAGFIVVPNCFDKIVEKKIRELDVDIIHTHHPMIIGNTAIRLGK
                     KLGIPVVFTYHTKYEEYLHYLVNSNVIHISNSKILEVCEKYIRCKMLPKYIRSYGNRCD
                     LLIAPSSEIKKNLIEKGIKTPIEILPTGVPDILFNTDYQSAQKIRQHYLNQKKFLFCTV
                     SRLAKEKNIDFIIKGLNLLKNDLGDIFNFIIIGDGPEKNRLELLCGSLNLEDNVFFVGE
                     KPNEIIKEYQAACDLFLFASTSETQGIVLIEAMAAGLSVIAVKSTGVNDVVIDGINGIC
                     TEGYIDKWVNGIKKVICNKNLKDNLCKGAHETAISYSSSNIALIAEKLYGKILNKKKAE
                     EYEKETDSYKANKRYYKFYNHQIFKKG"
ORIGIN
        1 gattagcaca ggtaccagaa gaactgaagt gaaatggtcc taagtgcaaa aaactggaaa
       61 agttatagag ataccacgta aacggtagaa tacgagtacc ttgacaaata gcagaccgct
      121 tttgcggtct gtttattttc cgctggtttt ttgcggcttt ctaatgtttt caggcaacat
      181 atctgaccat ggcagaagtt ctgcaagaaa atctgtgttt ttgtcatcta catgtttggg
      241 aatctccgta agcagatatt cgaaataatc gaaaggtttc aggttattcg cctttgcagt
      301 ttctgcgata ctgtagatga tcgctgaact attggctcca ttgaccgtat cgatcatctc
      361 ccagtttttc ttccctatac agaatccacg gatcgcacgt tcgctggcat tgttgtctat
      421 tggaacatcc ccatcttcca gaaagacttt caggtagctt tcctggttca gtgcatatgt
      481 aaatgcttcc cgtattttac cgttctttgg aatcttaggt tcattctgtt tcaggtacgc
      541 aaagaaagca tccaccagtg gttttaccac aagctgacgc tgcatgagcc tgtcttccgt
      601 agaaaaatca gacagttttc cctcttcccg gtaaatggcc tgtatctgtt tcatgatcag
      661 atgcaggatc gattcctttc ggtgtgcttt tggtatcact tccagtgcat cgttaaacct
      721 gcgcctgcag tgaacccagc agcctgcgat cttcagatct tcacgctcct tttccaatgt
      781 atgatatacc tggtacccat ccgtaacaca gaccccggtg taatccctca ggaattcccg
      841 gggatgggat gcattacgcg ttttctggta ttcataaagg ataatctgac gatcccggta
      901 cataaagccg gaccggtaca cccacatgta actctggctg ccggcaggac gcccgtcctt
      961 atttacaagt acaggagtct catctgcctg tatcacatga taatcataca gaagtttatg
     1021 cagataatca tacatggttc ccagatattc ttccccaaga cggatcatcc agttcgccat
     1081 gttctgtctg gtaatggcga gcccgtacct ttcgaattct ttttcaagac ggtagagagg
     1141 taccgcattt acatacttac catttatgac tgccgcagca agggacgggg atacaagact
     1201 tccatgaagc agatttctgg gatggggtgc ctttatcatg tgttcatcca gtttactgga
     1261 ataaacgccg atatgatgtt cctctatcac gacactggcc ggaatgaact gataacatcg
     1321 ggaaatggca tccggaagct gtttccatcc gttttcacca aactcagccg tcagttcttc
     1381 ctctttcagg tagtgatcaa tacgttttac tgtcagccct gctatatcag ccgctttttt
     1441 ccctggctgt tttttctttt tgggtgcttt cagttccagg tcatcaggtt ccggtgcatc
     1501 caggtcgcag actgcctctg cttcattaaa gaatacgata gttccgtcta cttccatgaa
     1561 acgtatctgt tcagaatccg ccattttttc gctggatctg ccaaaacggt tcttctggaa
     1621 aaggaccatc tgttccatca tcagctgcat cctgtcattt aaggcctgcg tttgcctgga
     1681 caattcttcc atctgtccct gcatcccaag aaaaagctct atcagcagat ccttatcaaa
     1741 cttattcagt tgttcttttg tgtacttgat cgtcataacc ggaactcctg tctttatact
     1801 gattccgatt ataacagaat ttttgtattt ccgccaatcc ttcagatatg ggctttcgtc
     1861 ataatgacgg tggataatac atctggaaag ccgttgtttt acagcttttc agatgtatta
     1921 tccacaatag tttttctatt cacacgataa caaatggaat gagaaaagac tgtttgtgga
     1981 taaccttttt catccggttg atacacatca tttttacagt tttggtactt ttttattttc
     2041 ggcattttgc acaggctaca taatgcgggg tgtctctttc agctcagaga tcggatggcg
     2101 tgcaacgatc tccagtccct gcatcagcat acggtactgg tcgtctgtga tcgccattgc
     2161 ctcatctgcc gaacggggcc accggaatgc accattatcg agtcttttgt acataaggag
     2221 aaaaccatcg ccttcccaga gcagtgcttt gatccggtca catcttcttc cacagaaaag
     2281 aaacagtgta tttttgtcgt aaggatcaag cttaaactga aagcgtacga tcgttgccag
     2341 tccatcgatc ccacgacgga gatccgtaaa tcccatcgcc agatacacct ttttaaatcc
     2401 ggaagcatct gcatcattca gcatgggtaa aagcctttat gagatggcag agcatttccg
     2461 gtgaagtacc ggaaaatatc tcagctgaca gtcccctggt atttttaata cggatcattg
     2521 gcagagttcc tgccgaaatg catgtaccgg attcttttgg agtatctgtt ttctttggat
     2581 ctggtgcagg tgcgggcagt tccacaaaag cagtggtttc tgtgtcctgc atctgatcta
     2641 ggcatatctg cctgacacgc cggagacggt aataatagtt ggcttttgta agattatttt
     2701 gggtacacca ggtttcaaca tccatccctt tgggacggtt ctgacaattc cggatctgtt
     2761 ctgcccattg tctgatcctg acctgctgag ctacaaggct ggtttgcgta gccataatat
     2821 tcctcctctg aatcatagtc agttaaaaaa gttaagtact aaactttttt gactatatta
     2881 ttttgttgag tatgattatg gcataacttg aagtgaataa aaaggtactc aggttctacc
     2941 gtttacgata ccactcctta gagggattat ctcataaatt ttggatactg aaaaaccggt
     3001 ggattattca tcgcttacta ttatattttg tccaaccaca aaagagtgct atatcaatgc
     3061 gatcattccc aaagaataat ccaatgatat agcactcttt tttatactaa aatttcaaaa
     3121 caaaataaac acaattagat aattgggcaa ttaaaatgga taactggtct tcattccata
     3181 tagcgagcat aaaaatctag taatttttcg gtaaaaccac ttttcctatg tttgctaact
     3241 ggtatatgaa aattattctc caacttgatt tccaatctct catacgtatc tatgtgcaaa
     3301 aggttaacaa tgaaacttgc atggcaccta taaaaattag tatccaactt atcttctaac
     3361 agttttaaac aatggtaaca tttaacacta ctatcttttg tatgtattaa tacatgctta
     3421 tcctctgttt caataaaata aatatcttca aaatataatt taaataatcc ttcaacattt
     3481 tttactatta aaaatttccc atttctgtag agttggttat atatttctaa tatcacttta
     3541 ctcattacct ttttcgatac tggttttaaa atatactttt ccaaacgtat attatatcca
     3601 gcaatggcat aatttttgat tgatgtcaga aaaactagtt taactttgtt atccattttt
     3661 ctaatctttc tagcgacatc ataaccgttg atcggattca ttaaaatatc aagtataaat
     3721 acatcaatat ccttatgtac ttcaaaatag ttcaacaatt ccttgccatc aataaatttt
     3781 attattgaaa taggaatgtt taattccata cgaatttctt gaagtatttg ataaagttta
     3841 tcaagaaatg gcttttcatc atcgcaaata gcaatcttca tcaaatcact cctttgtata
     3901 aaacaaacgt atactaaaat ctaaagttac ccttctctca tttttttgag tttttcagga
     3961 acctggggct gatgcaaaat tattaaacag tgcgggtatc ctaaagcaac cgtataaact
     4021 gcaacaaaca tagacatctt tcccatcatt ttaaaaagag attttttcca atttttcatt
     4081 tcttcctcct aatctttaag ttttcctaca gctacaacaa tacctatata tgttaatgca
     4141 gcggaagctc ctgatatatg tgatgaaaat ctcaaaataa cattacataa tatcagaaca
     4201 ctgacaataa cagtcaaacc aatagctttt ttctttagca ataacctttc agaatctaaa
     4261 ataggatttt gtaggctatc taccggggcc catgaaatta ctactaaatt gattatgcat
     4321 aaagtaataa acgcagttac aaatttacaa tacaaaacgt tccaaatagg cgagcacata
     4381 taagctaaaa cgaatattaa aatacaatag aaattatttt tggcatgata tccgccagca
     4441 taaagacgaa tactgcagta tgtagtcaaa taaataactg tgtaccaaaa attatgttgt
     4501 aaaattccaa ttgccaatac ggaaattata cttatcagag aatttattat gatttctaat
     4561 ccataagcat atatatcttc attatccttt tcattatttt caaggacaat tttttgagct
     4621 aaaagcatgg atattctttt tatcattact taatcaactc catccaattt aaaattattc
     4681 atgggcatca agattctcgt tataaacttt ccattattta tttcatattt gtattcgcca
     4741 tcatacttat tcacaatcat ttttatactc tttgttccta tgccgtgttc tttaacagaa
     4801 acctttgttg ttaacaaaac attatgtttt cttttaatca actttttttc catatcattt
     4861 tccacgtata taagcaaaaa tttatttagt cttttaactt taatcaaaat ttctgttttt
     4921 tgagtactaa ctttttcaca agcctcaata gaattatcca ttaaattccc gaacaatgag
     4981 catccatcaa tatcattgat aaacttaagt attcccttct ctatttgaat atctatctta
     5041 atatttttag acatagcaat cttggatttt tcttctaata acatgtctat tatttcgttt
     5101 ccagaatcaa tattattatt tttttcaata cgtgttagca actcatcata gtataaactc
     5161 tccttttctc cttgtgccac taatatatgg tttttaagat catgttgtat aatttgcagt
     5221 tccttcagtt tttccaattt acttttataa agctcgtatt catgttttgc cttttgtaca
     5281 ataacttcat tatcatactc tcttttcttt atctccatat agtgctgaaa aacatttata
     5341 tgcgtgtatg tgaatacaca tagcacaatt gatatcagaa taaaagcagc cattatatca
     5401 tggtatctta cattttctat atccaccaaa aagttagcaa agaaaataaa tatcagaaaa
     5461 gtattcaata atggtgtgta tgtaataaac agctcacttt tactcatttt tatttcatgt
     5521 tttttcatta ccttcattga caatgatatc aaaatcatag acaatagctt tgatgatata
     5581 taagaataaa accatataaa cttattatca taaaataaat caatatcata tatacctgtg
     5641 caaagcatca caatcggcaa aatcaaaatt tccgaagcgc ctaacaacat taaaaaaata
     5701 actgttattc ttaaagaatc taaaatgtat atatcttcgt atacgatgta tatccaaaag
     5761 attagaataa ctatttttaa gatcaatttt ataagaaaag aaaaaggaag aatatttatc
     5821 aaaacattta taaatgtgca gcttataaaa catacaaaaa ataccatttt atttacttta
     5881 actgctctat ctttaatata gtaaattagt agacaaatat cgaagaatgt tccgacaaag
     5941 gttgatacta aatcaatcat tcttatcacc tttatccgca tattcatcta ttgcatattg
     6001 gcaacactgt aataccaact gattaaatga tacctgttca ctctcagata ttctcaacaa
     6061 atccccatag atattttcag taaaacgaat agttctggca acattacact ttgctaaatt
     6121 cttattaacc ttaaacatat gattgcacct ctgatttttt tggtttatta taaccgttta
     6181 agataccaag ttatataacc ataagtgtaa ccatttgtat aaccatctaa tcattcagaa
     6241 tgtttccagc atagatttta gtattttatc gttaagcctg aagccattac ttcaggcagt
     6301 ggcctgatct tgccctcaga aggggctagc ttgcatgtat gccttaaggc acaagcatta
     6361 ttacaggcaa gcctgtcata tgtccttaaa gtgcttttcc ccctttagct ctcatgaaac
     6421 ttgacgtaca ttttgacggc atactaacat atattttgcc tctgcttatt ctattttcca
     6481 acatagctgt ggaatcagtc cttccattta taaaaaattc tttctttatt acttattttt
     6541 cctctattta attctatata ggcgtaagaa agttataaaa attctacatg cattgtaaaa
     6601 aagatcaatg tatatttgtg tgttttacat aaatttagca atgtaagtaa ttgttcttca
     6661 ttaagcatat ctatatcggc aattattaat tcatacatgt tatatataca tcttgcaaat
     6721 aaaactgata cctgtttcac ccaatccaat tcttttggat aagctttaag gctattttct
     6781 aaattaaaat cttttgcaat tgcaatcaat ctctcattat ttttagtttg cgcacttaaa
     6841 tctatcggca aaactatatt taattccaca ttataattat caattaacaa taaatttttt
     6901 gtaattactc ctatttttct tctcaaatat gtctgatacc gtttatcatt ggtatctatt
     6961 ccaccaattt taatatttcc cttacttggt atttctaaca gactaatgag atttattaat
     7021 ctttctttac actctaaatc atcaatatat attccaaata tatcacctgt aagtatattc
     7081 aaatcagtaa tttccaatgt atatcccttc atttgctctt tcaggttctg tatagtaatc
     7141 atacatattc tccattccgc catttgacaa atccggataa ctattaaaaa attgatagct
     7201 acctttataa ttatcaatga atcggtctac ttcccctctt attttgtctg gctgatccgt
     7261 aataatgcca cttgctccca tttctaaata ctccttaata tcttttttat tatttgctgt
     7321 ccatatatat actggcagcc aataatctct ggctttagaa atgaaattgt aatttgcctg
     7381 tccttcttct attgctagaa agtctatatt tagctccaat attgactgat ttaactcccc
     7441 gacacttcca aatacacaat aaccgatcca ccattcaggt ttcaattttt gtaactctat
     7501 tacgaattta taatttaatg acataaaaat acatttatga ccaaaagaat tcttttcaac
     7561 tatatcaaca actttttcca caagttcatg agattctccc ttcagttcta tcaatagacc
     7621 aattttattc acagaactct ttgctgcctt aataacttct tctaaggtag gaattttatc
     7681 aactttatta ttagaagaaa gatttaattg ttttatttga tttaaagtta gattctcaac
     7741 atttgaaaat ttgtcacata acctgagcaa attagaatcg tgaattacaa taggaacttt
     7801 atcctttgtc aattgaatat caatttcagc atagtccgct ttaaatttgt ccgctgccaa
     7861 aactgcatta actgtatttt ctatttcata tttgcaacct ctatgtccta tcacccaagg
     7921 ctcatgcact tgtggtggac tttgaagata tacaaaaaga atcacaaaaa gaattccaat
     7981 tatgcccaat ttaatttgca ttctgtattt taaaataaaa ctattgttat ataatttttt
     8041 tcccatgccc ccaaaaaact tcagactttt ttgccccaac gttaaatcta tgcctttata
     8101 tgatgctttg taatcagaag gtaaatctat taatccattg cttattttta taaaaaataa
     8161 aagcaggacc atattaaaaa caattaatat agcatttaaa attatatctt caaaaacagc
     8221 atttctgaac gaagtgtttt ttataatcca ctttacggta taaatactga agtcagaact
     8281 tttcaatttc aagtttccaa acttagtata ttgaaccaat aaaaacactg atataactcc
     8341 aaggaattgt aatctctttt tagcaaaaat acttttagct ataacaaagg attttttaca
     8401 tgcattataa aatccaatat cgtttactac cattaaaatt ggaataaaag ctgtacttgc
     8461 aaatattata accttggata taattagtaa gcatttaagt acaattccca aagacattcg
     8521 gtctatttct ccaattacaa aattgggaat tgccaatttt ggtactagcg aattaatata
     8581 aacaaaatgt agaaatggta acactccaac ataaaaagca gcaataccta taatattttt
     8641 tcgtattatt tttttggtaa tatcaactgc gatgcataca acagtaaata cttttattct
     8701 attattattg tatgttgcta tcccaataat gatgtttacc gatatttcaa agaaaataca
     8761 gatagtaaat accattataa taatcactaa gatgattaaa cttggccatg taaaaaaccg
     8821 acttataata tcactattaa aagaaatatt atatccgttt atccacagat atttatcaat
     8881 aataaatttt attattggca ggataattat taaacaaatt atcttaaaaa gtatttcaaa
     8941 tttaaaagct tctaatagat tgctccaaaa cacttttaaa caatgcattt cataatacct
     9001 ttctttgttt tccggtctat gtacatttag aacatagacc ggattccttg ttaatttaca
     9061 tcagataata ccggtgttcc gcgccaaggt tcaatacaat cgttcaagca tcttttcttc
     9121 gtggaagcac aatattcata tagttcaact tctatttctt tctgctcgtt ttcttttaca
     9181 ttttcatcat tcatgattat ctctcctaat ttacatcaga taatactggt gcctcaaatg
     9241 gtggaacaca atcggttaag cactgttgtt ttgttgtgct acacgtgcta tatccatcaa
     9301 tagtatctac ttcttcttca aaatcgttcg ttttttccat tttctatagt ttctcctttc
     9361 tactgttatt tatttcaaag tagctaataa gagtctgtca attgcttcat tctaaacaca
     9421 atactctctc cttcttgatt ctttattaac aataatggca tgatgattga gattccaaaa
     9481 tataatagta aaactgcaaa tagtggccaa acagcaaatc tatatgatga gcaccaactt
     9541 gtttctataa tactttttac aaacgttcga cctaacaccg aagataacat tattgaaaat
     9601 atacttacga gagaaactat ataaatgttt tccaacaaca gcatattttt taattgtcgt
     9661 tttgtcatac cgatactatg caaaataaca aattcatgtc tgcgggaaat gattgaactt
     9721 gcagcagtat ttatataatt cattatccca ataagtccga cgataatact catcatatac
     9781 cctaacgcgg tttgtgaaaa tatttgcatc tgaaattctc tcgcataagt ctgcttggat
     9841 ttaacgtcta ggttcgcatt atctttctgg aactcattta aaagcttctg tattttacga
     9901 ttcttattat cactgacatt tataaagctt tggtatatac taggttcacc atgcaacttc
     9961 ataaaagaat tggtggacat cacgaaacct tgtgttaaag gcgctgattc ttctggtata
    10021 cttcctaata ctgtatcggg aatatctaca tatcccatca ccgtataaat cgaattttta
    10081 attttgactt tatctccaat ttcatatatt acttcataat cactatcatc atcataccct
    10141 atggctaata cataattctc atgttcaaat tcctttggcg aaaactctcc tgaaaatatt
    10201 gcacacttat ttattatatc tgcatcaata ccatatactt tggcttgcat tatcttttta
    10261 cttattaatt tttctacttc ctcttcatat tctttattac tatttttatt tttcctaatt
    10321 accttatcat agacatcctg gtcatcaaaa gatactgtat caatatcaaa gtacatgttg
    10381 cttatttgtg cgttactgtt gattgctttt atttgtgaaa gcatatccaa tgtcacagta
    10441 ttatttggtt catactttct tgtataactt gaaacacaat aatcagatag actataatca
    10501 ctcaccattt tcgtttcaat atacttatcc agatcaaagc tgtttccaat taaatatgta
    10561 ctttcaaaaa gtacagtact cattactaaa gaacaaataa ccattatcac acgtttctta
    10621 tgcctaaata aattaatcca tgacaatcta gatatattga tatattttct atttttatgc
    10681 ttcacaaaat tactatcaaa atatttactt gcatttatag gcgaaacttt agaagcaacc
    10741 tttaacgctt ttctacttga tatccaaaca gtaaatattg tgcacaaaat acttccaata
    10801 aagattatcg gactcatcga catgtttaat gattctctcc caagactgct atctaatatg
    10861 ggaggtaata ataaatagcc tatcaaatag cccatgatta gtcctaatga aactcctaca
    10921 attgcaaccg gtactgtttg tacatataac aactttttaa tctgtctgct ggttgcgcct
    10981 ataagcttaa gtgatccata gaagtttatt tccttgacaa tggatatttg gtatatattg
    11041 cttataataa gataaccact tagaataata aagaaaaaca ttcctcctaa agctaacata
    11101 atatttattt tctcagtcga acttatttct gaatacgctc cgctagtgtt aaaatcaata
    11161 ttttgcaatc tttcttcttc caggatttcc tttgcaatct tttttgaatc atatttatta
    11221 tccgttttaa ttgacagcat tcttagccca ttcaattctt tattatcaga tgaccaatac
    11281 ccctttagat attcttttga catccagatt tgactagcag gcgcaatttt atctgcctcc
    11341 caaaagccac ataaaacaaa cttatcttca tggggattcc cgtttatatc tacaaattcc
    11401 aattccactt tttcccccag cttatgggga ataccgagca tatcaagcac taaagtatct
    11461 gttgcaattt cccttttttc tttaggcatt tgaccttttg tcggataatc aaaactcatt
    11521 ttcgcatatt catcatccgc atatcgcatt tcacattgtc gttcaataag gcttgaatta
    11581 tttgccaatc ctagtattat gcttttgcca acttttttaa tatttttatt atcatttgaa
    11641 gctatctttt tttccgcctc ataagtcaaa tatttaaaac taatatctgc ttccccgcca
    11701 acctgtcgta atgcagatat ttctatactt ttatttaaac tcaatgctat tgtaaaaaca
    11761 gatgtaaata gtactgttgt taaaaaaata gaaataacaa gaattatatt ttttaaagga
    11821 tttagcttta atttgcgaaa tgataagtga cgtaaaatat cattttcggt aagactaatt
    11881 ttcattgcca ttactcctta tattatctac aatctttccg tccttaagtt taataacagc
    11941 gtctgctcca taggctattt ctaagtcatg tgtaactata attacagtct gcttaaactc
    12001 tttacatata gttttcaata agtgtataac atttgcacta ttatcaccat ctaaattgcc
    12061 tgtcggctcg tctgcaataa ttatttgtgg ttttgacagt agtgctctgg caattgctat
    12121 acgctgctgt tctcctccag ataaattatt cggatattca taaatttttt catttatatc
    12181 taattgaagc agaaccttgc tcaaaaaata ctcatcaatc ttttttttgt ctaaagcaat
    12241 tgggagtata atattttcat agacatttag ttcaggtaac aaattgtaat tttgaaaaat
    12301 gactcctatg ttttttcttc taaatataat tttttcattt tctgacaaag acgaaatttc
    12361 aatatctcct actgtaactg tccctttatc aggataatca agaccactaa tcatatttat
    12421 caatgtcgat tttccactac cgctttttcc tataatagct gtaaacttat tatcctcaat
    12481 tcttacagac acattatcca acgcttttac ctgattattt cctttgccat atattttaca
    12541 aacattattc aaatatactc gatacaatga ctgcaacctc cattcttact tcatctttaa
    12601 ttttattgca ctttttatca gcagatattc cgtcttagaa ttgacccttt caaagtcaat
    12661 aaaattgatc cttatatgag agcatggcaa tggaattaca tatttatccc atctatgtgc
    12721 tattcggatt actttctcat attcaacact tatgccaact atcttttttt ttgaacagct
    12781 accaagataa aatggcagtc ttttaggttc tttaaatgga cctagtggtc cgtccattgc
    12841 aattgcaata atattatctt tatttgctaa ttcttttaaa tttttatact cttttacatc
    12901 gaatgcatta aagtcaatcc ttatggattc tgcaccaaat ttttttatcg ctgcctctat
    12961 ataatcgcct ctgggatcag cagtaattac gacaacaatc ggtttaaaat tctttttttt
    13021 taaatagctt aaaaccaaat tcattgtaca actatctcta tgccaaaata ccgcaattga
    13081 attattagat aacatctcgc cgttttctat aattatatca gcaaatttct caaccctttt
    13141 taaatatttg atgattataa aacttgtaat acctcttatt cgctttataa gaatctgttt
    13201 ccttttcata ttcttctgcc ttttttttat ttaaaatttt gccgtataac ttttcagcta
    13261 tcaaagcgat attagaactt gaataactta ttgctgtttc atgggctcct ttacataaat
    13321 tatcttttaa gtttttatta cagatgacct tttttattcc attcacccat ttatcaatgt
    13381 atccttcagt acatatccca ttaataccat ctattactac atcatttacc ccggtagatt
    13441 ttaccgctat aacactcaat cctgccgcca tcgcctcaat caacacaata ccttgtgttt
    13501 cggaagtcga tgcaaataaa aacaaatcac aagctgcttg atattcctta attatttcat
    13561 taggtttttc cccaacaaag aatacattat cctccaaatt taaacttcca cataacaact
    13621 caagtctatt tttctctggc ccgtcaccaa taataatgaa attaaatata tctcctaaat
    13681 catttttcag tagattaagc ccttttatta taaaatcaat atttttctct ttagctaacc
    13741 gagaaactgt acagaataaa aatttttttt ggttaagata atgctgccta attttttgag
    13801 cactttgata atcagtatta aaaagaatat ctggtacgcc tgtaggaaga atttctatag
    13861 gcgttttgat tcctttttca atcaaatttt ttttaatttc actactaggt gctattagta
    13921 aatcacaacg atttccatat gatcgtatat atttcggcaa cattttacag cgaatatact
    13981 tttcacaaac ttctaaaatt ttagagttag aaatatgaat tacgttactg ttaacaagat
    14041 aatgtaaata ttcctcatat tttgtatgat aagtaaatac caccggtatt cctaattttt
    14101 tgcccaaccg tatagcagta tttccgatta tcatcggatg atgagtatgg atgatatcta
    14161 catcaagttc tctaatcttt ttttctacaa ttttatcgaa acaatttggc actacaataa
    14221 acccggcaag tttttgagag aatgatttgt atctgattac atttacttct gcttcctgcc
    14281 cttcataagt tggtgcaaat atatatactt catgacctaa catttcaagc ccattagcca
    14341 aacgttcaat tgatattggt acacccccta taaagggttt ataattatta gttagcattg
    14401 ctatcttcat aaaattctcc atttcacatt agatttactc cagtttcgtt atcgatacac
    14461 aagtgtacct tttttcctag agcaggaaac tcatcaaatg atttatcata tttctttcat
    14521 ggctgttttt cacgctatac ttcccaaaat ttcgaatatc ctatcaccaa aagcaaatcc
    14581 aactccaaca aatataaaat tccatacaaa aacgcctacc aaggaaccca atgtatatct
    14641 gtaaaa
//
