LOCUS       gnlProkkaMDLEHPFK_159  14321 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDLEHPFK_159.
ACCESSION   gnlProkkaMDLEHPFK_159
VERSION     gnlProkkaMDLEHPFK_159
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:12:56
            Original ID  :: gnl|Prokka|MDLEHPFK_159
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14321
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14321
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1690:4321]"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1691..4321
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     cand_cluster    1..14321
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14321
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     CDS             2..157
                     /locus_tag="ctg159_1"
                     /transl_table=11
                     /translation="MFSNKRDRTQLAVGVSKPYTYILGGDLKYVDGIIIWGGNVYGNWG
                     WGVDVW"
     CDS             314..1552
                     /locus_tag="ctg159_2"
                     /transl_table=11
                     /translation="MISDAILYKYRDFFRINKKTEKIILFSYISIMLTWQYWVSYVSFG
                     IIAIANLYLPFFLLLFYKCDFIQAYLWEVLYLVNIGLAKILYIYIIGMIKHRRIENFLF
                     SKSVHFYAGVVYLLIFYVLFLIIQKNFCVEKWLKDLLTDCKKMILFVALSECSILYFLL
                     TMNWGYIENRELIISFGVISGIALILLFVLARFWAKSIYTEKNILEVRNNVIASQYEEL
                     NESYKKYRCLIHDERHMMDYIEECIGTGNFSEAQKIIKKSRNKFSERYYWTGITVLDNV
                     ISIEKRKMDNMNIEFHIETDVTDIVMEDIDIIILLENLFDNAIEAVEKCANKKEIKFSI
                     KNINSMLVLKLWNSSCKKPKVKKERFVTDKHDSKGHGWGLESVKYIVKKYDGIIEFEYT
                     EMFFQTVIMIEGE"
     CDS             1555..1698
                     /locus_tag="ctg159_3"
                     /transl_table=11
                     /translation="MDENIKYELAEAEKLEVIDNAGVAENEKKSIVTVLLSLSCCGHIM
                     NA"
     CDS             1691..4321
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070:lanthionine synthetase C family protein (Score:
                     839.8; E-value: 5.1e-254)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg159_4"
                     /sec_met_domain="DUF4135 (E-value: 7.3e-95, bitscore:
                     311.0, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.3e-58, bitscore:
                     189.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLENICIRILILDISEKKSNHELYGFTVHEEYNFYIKHFWKNESY
                     KCDLAIRYAEGSRLQKLKEKYFVILQNEINEKINIDKDMISKKFHENMNEFQMLNKDQG
                     DIHKNGRSVSKIEFDNGSILYYKPHSLDKDIKYQQLYKYLCEKAGISCREVRCLSRQTY
                     GWEENIENKSCNTKEEIERYYFRLGIHLFLGYALGATDLHGENIVAYGEHPVIIDMETY
                     PGYITKNSGSSTEEKAEIKIREKIMTSVLNTGILPVLTWGTGNNRVLMSAVNMHGKIRT
                     PFKMPVVKDDKTSNIHIEYEQVEFEIKECIVRLNGEVVNSEEYTGEIIRGFRMAYTEIL
                     QNQKLRNMLKTFFQGKSRVILRHTQQYYMYLFASFHPDYMKDRKQREELLQVLHKKGET
                     QLQKELRDYEIQSLLELDIPYFEIDGNSRSIFDGNGKEYQGYLPCTPYESWIEHMKQLS
                     CQDMEQQCDYIRLSMGLLNHGYIGEKNPRWADENTCIHQIAEWICRTAVIDGADIGWAG
                     LHFWDNGYWSLKPCGMYLYDGIAGIVLFLAKYLDRYQDSSCRQDVEKIYKLAIEKLEKY
                     TDLRCEQNEVPEPLATGLYDGESSIVYVYLILYEITGQEKWIKNAQKHFEIVAKLLPKD
                     ENMDYLSGNAGAIVAAMKLYQLTGEIEYCTAAVETEKDLWKKGQRMEVGYGWKLKNLKY
                     PLSGLSHGNSGFLMAYVELYKMTYDQEYLKKIKLLLSYEDILYSEDLKNWIDLRDPDGR
                     KTMRGWCHGAPGILLSRMSIMDILPDDKQIKKDILRAVSTLFHNEREKKICLCHGMTGN
                     LLIMKKYLEKNPDDDLRQKYERQFSNLKEQLQDMRSLMVTETLNPAFMNGITGVGMAMM
                     LLNMD"
     CDS             complement(4342..4872)
                     /locus_tag="ctg159_5"
                     /transl_table=11
                     /translation="MKSLLQLIHDYHSGVKNAGEEILKRMEPLIKSYASRIHCMERDDA
                     TQELYLTLLNTLPYLNGKNFSEGECVRYMQTAIENRYRALCRYHLSEPEREDFDTCSLT
                     LQADNPFDETLYDITTYIESFPVQSMEYKILSLFFYQYKTDSEIASILHVSRQYINRQK
                     KKLLKTYFFRHPD"
     CDS             5091..5321
                     /locus_tag="ctg159_6"
                     /transl_table=11
                     /translation="MESTVMETAISQGIWAVLAVFLLIYIVKSNEQRDAKQEEREKNYQ
                     TVIENLTEKFQILNQVQNDLKEIKDNLLNKN"
     CDS             5527..7641
                     /locus_tag="ctg159_7"
                     /transl_table=11
                     /translation="MKEYKVITALFLSAVMLGTAPLTVWGAESFSTGESFSDGTENIPD
                     IVTDSALSGESSERDYELSIETGTDVELTESDFYDPEFRVEKYVKVRNSGKKETRVRVD
                     ASGLKNFEVDDQMAKWSEDYEEQDSKRLLKPGETLDFFVLPKQEYGTYDETFDFLADDG
                     SRYPVHITMNREKNPTEKKSLEITEKSSESFPIMHWGYKTLPEARIYVLKNFTDMDMEL
                     SFDYSKDCSVSLCGNTSLAPGESTELSLCPQMGLPVGEHDLGVTVTAKTATGETITKKI
                     WDSFRVDSRTFQGLVDTIEPVTGITNGVEKTADALHLPSVLKVYGAEVDGEKTTFSADV
                     KWDVENCAYNPKNTASQSFTVNGQLELREGENNEELDTSVKIKVQVDAYKGLNRPVIDS
                     TWTRVITNYAELSLRDTSNEADGYFFVAAESQKELEKENYIAQVKVAKSELNHYPKLKY
                     IPEGTHYLYCRAYKEESGHTEKYGEWSEGFLLKVNIKTPNAPVVQKLQVKKNDVKIILG
                     SNTEELDGYDVVAARSKDGDEPSDYIKVQCKYSGNSKELILKGVPKGNWYIGVHGYKYL
                     DGSNKKVLSKWAEVQKVTVKTSLVTGKPAVKSAKVSRQGTKRKVTVKFTVPKACDGTDW
                     VLAKKVSQSEDGSYTYVSGYAYTKKNQTKTTVIFKNVKPGVYYLTGRAYVKGYAKNYTK
                     WSEVKKVVVK"
     CDS             complement(7651..7860)
                     /locus_tag="ctg159_8"
                     /transl_table=11
                     /translation="MPETLTFSVVNWKESDAECTFTVVNSGFGYTTQLQNKYYHTSFGL
                     FILTNNTFFFDIYIYMQKKNKFLV"
     CDS             8386..9102
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 213.6; E-value:
                     5.3e-65)"
                     /gene_kind="transport"
                     /locus_tag="ctg159_9"
                     /transl_table=11
                     /translation="MNEMTDAYVKLDKVSKIYGTKEVKIVAVDEISFEIAKGEFVVIVG
                     PSGAGKTTVLNILGGMDQATSGEVLVDGRNIARYNSRQLTGYRRNDIGFVFQFYNLVPN
                     LTALENVELALQICKNPLDAREVLEEVGLKDRLTNFPAQLSGGEQQRVSIARALAKNPK
                     LLLCDEPTGALDYQTGKAILKLLQDMCRERGMTVIVITHNSALTPMADRVIKIKNGKVS
                     RMTMNDHPTPIEEIEW"
     CDS             9103..12888
                     /locus_tag="ctg159_10"
                     /transl_table=11
                     /translation="MMNMKAMHKDFWMEIRKSKARFISIFMIVALGVAFFSGIQASSPD
                     MRFSGDAYYDETNLMDIKVMGTLGLTEDDVAAIKQVDGVENAEGAYGTDVMCGEGEKQK
                     VLHVEAVDQTMNRISVTEGKAPEKSGEIFLDCIFAESNGYKVGDQITLKEGGGSELLKK
                     TDYTVVGLGESPLYISYNRGNSTLGSGEVNGFAYVLPEDFDQEVYTQIYVQAHGAQDLI
                     SYTDAYDSLIERVQERVEGSEAERCQVRYDEIVEEANDKLADARQELEDGKKEANEKLA
                     DARQELEDGKKKLKDGKKEYKDGKKKLADAKKELEDGKARLADAKKELEDGRSQLASAK
                     EQLASGRAQIASAKEQLNAGWAEVSENQAKLDDGKAQLEDGKNQLSAGEKQIADAKTQL
                     TQSQQELDNGKAQIQSGREQIAATRQDLNAKKESCNQGLAQIEQQEAGLAEGEAQLEGA
                     RSQLAALQAQYEQAQASGTYSEEDLAALAAQVSAYQEQVDSQAAQLEASRNQIAAARSE
                     LESGLSQVESGLAQLDAKEAELNQQEAAFPDAQAKIDAGWKEVKAQEKKLEPARKEIQE
                     KEAQLESAQEQIDAAKAKLNSSQAQLEEKEAELASGEAQIRENEGKLASGEKEIADNEQ
                     KLRDGEKEISENEQKLKDSRKDIKKAEKDLEEGKKEYEDGKRDAEKEIADGEKKIQDAR
                     DEIDDISMPEWMVTDRNDLPEYSDYGDNADRMRSIGQVFPVIFFLVAALVSLTTMTRMV
                     EEQRTQIGTMKALGYGKYAIASKYLLYAFLATVGGSILGILIGEKILPLVIINGYGIMY
                     KGMMNNIQIRYEFKFAMIAAGAATVCTVGATIFSCYRALAETPASLMRPPAPKEGKRIL
                     LERIPLFWKHLNFTWKSTLRNLFRYKKRFFMTIFGISGSMALMLVGFGLRDSIMDIARR
                     QYQELQHYTGTIIDDEDATDKERQELDEFLKNNSQIERYTHVQFTKMSVPRNKSNISVY
                     VYVPENLETFNKDVTLQDRKTKEKYKLTDAGTVISEKTATLTGLKVGDTMTITKNGKNY
                     ETKIAAVTENYMGHYIYMTGNVYEQTFGEKPNYSATVFTVKEEYKESESEVGNEILKHP
                     AALSISYTSSLEAQLHRMLGALDTVIVVLIISAGMLAFVVLYNLNNVNITERQRELATL
                     KVLGFYDTEVSAYVYRENVILTLIGVLAGAVFGIFLHRYIIRTVEVDAVMFGRNINPVS
                     FLYCGLLTIGFSMIVNLFMHQKLKKIDMVESLKSVE"
     CDS             12995..14200
                     /locus_tag="ctg159_11"
                     /transl_table=11
                     /translation="MGTANQIEQELMSYISDHKIRNTHSHHLPEQAMVDFDLDKLINNT
                     YLQWQQVTPGTTAESRTAYLEKTRYKSYFVWLQKAIGELYGISEPITAQNWNQISDQIR
                     KAHQNPDFYMDVLKNKCKYQKVIVDTYWNPGSDNGRPELFTPAFRLDLFFLGYKKGLRN
                     HDGVSLEENFGELPDNLQDYVEWVRKWIIQKKSEGCVALKIAMAYERSLHFEKVTREQA
                     ERVFRLQESDITQEDIRCFQDYLFWKICEIAAEVSLPLQCHTGMGQVIDTNILQLNNVI
                     KNNPETKFVLLHCGFPWVDDLFSIVDGYPNLYPDLTWLPILSYTASKRVMHQLIEMSQI
                     DKICWGCDTWTVEESYGSLLAFRFSLCSVLREKIEDGYLSVNNAKDIIDKILFDNAGKI
                     YV"
ORIGIN
        1 cagctttagc aataagaggg atagaaccca actggctgtt ggggtatcta aaccctacac
       61 ttatatatta ggaggagatt taaaatatgt ggatggtatt attatatggg gtggcaacgt
      121 ttatggaaac tggggttggg gtgtggatgt ttggtaggat gtttccagaa cggaaatcca
      181 gttcagaata cagatgggca aaaatgatac ttttaacgct cttgattttg acaacatata
      241 ctatgcatag agcatatgga caagaatata tatatatgaa aaattttttt ttatagttgt
      301 ttatgctgga gtcatgatat cagatgctat cttatataaa tatagagatt ttttcagaat
      361 caataagaag accgaaaaaa taattctgtt ttcatatata tcaataatgt tgacgtggca
      421 gtattgggtg tcttatgttt cttttggtat tatagcaata gctaatttgt atcttccatt
      481 tttcttgctt ttattttata agtgcgattt cattcaagca tatttatggg aagttttata
      541 tttagtcaat attggacttg caaaaatttt gtatatttac attataggaa tgattaaaca
      601 tagaagaatt gagaattttc tttttagtaa atctgtacat ttttatgctg gtgttgtgta
      661 tcttttaata ttctatgtac tttttttgat tatacaaaaa aatttttgcg tggagaaatg
      721 gttaaaggat ttactgacag actgtaaaaa aatgatttta tttgtagctt taagcgaatg
      781 tagtattttg tattttttat taacaatgaa ctggggatac atagaaaaca gagaattgat
      841 aattagtttt ggagttatat cgggaattgc attaatatta ttatttgttc ttgcacgttt
      901 ttgggctaag agcatatata cagagaaaaa tattctggaa gttaggaata atgttatagc
      961 aagtcagtat gaggaattaa acgaaagtta taaaaaatac agatgtctga tacatgacga
     1021 gagacatatg atggattata tagaagaatg tatagggacg ggaaatttct cagaagcgca
     1081 gaaaatcata aaaaaaagca gaaataaatt cagtgagagg tattactgga cgggcataac
     1141 agtattggat aatgttattt caatagaaaa aagaaaaatg gataatatga atatagaatt
     1201 tcatatagaa acagatgtaa cagatatcgt tatggaagat attgatatta ttattttgct
     1261 tgaaaattta tttgacaatg cgatagaggc ggttgaaaaa tgtgcaaata agaaagagat
     1321 taaattcagc ataaaaaata taaatagtat gcttgtatta aagctatgga acagtagctg
     1381 taaaaagccg aaagtgaaaa aagaaagatt tgtgactgat aaacatgatt ctaaaggtca
     1441 tgggtgggga ttggaaagtg taaagtatat agtaaaaaag tatgatggaa ttattgagtt
     1501 tgaatataca gaaatgtttt ttcaaacggt tattatgatt gaaggagaat aaaaatggac
     1561 gaaaatataa agtatgaatt agcagaagca gagaaattag aagtaataga taatgcaggg
     1621 gttgctgaaa atgaaaaaaa atcaattgta acggtattgc ttagtctgtc atgttgtgga
     1681 catataatga atgcttgaaa atatttgtat tagaatattg attttggata tttctgaaaa
     1741 gaaaagcaac catgagttgt atggctttac agtgcacgaa gaatataact tttatataaa
     1801 acatttctgg aaaaatgagt cttataaatg tgatttggca atacgctatg cggaaggaag
     1861 tcgacttcag aaattaaagg aaaaatattt tgtaatatta caaaatgaga taaatgaaaa
     1921 aatcaatata gataaggata tgataagtaa aaaatttcat gaaaatatga atgaatttca
     1981 gatgttgaat aaggatcaag gagatataca caaaaatggt cgcagtgtat caaagattga
     2041 gtttgataat ggcagtatat tgtattacaa acctcacagc cttgacaaag acataaaata
     2101 tcaacaacta tacaaatatt tatgcgaaaa agcaggaata tcctgtcggg aggtgaggtg
     2161 cttatccaga cagacatatg gatgggaaga aaatatagag aataaatcat gtaacacaaa
     2221 agaagaaata gagcgttatt atttcaggct gggcatccat ctgtttctcg ggtatgcatt
     2281 gggagcaaca gatcttcatg gagaaaatat tgttgcgtat ggagaacatc cggtgattat
     2341 agatatggaa acatatcccg gctatattac aaagaatagt ggaagtagta cagaagaaaa
     2401 agcagaaatc aaaataagag aaaaaattat gacatccgtg ttaaacacgg gtatccttcc
     2461 tgttctcaca tggggaactg gaaacaatag agttcttatg agtgctgtaa atatgcatgg
     2521 caagataagg actccgttta agatgcctgt tgtcaaagat gataaaacat caaatattca
     2581 catagaatat gaacaggtag aatttgagat aaaagagtgc attgtaaggt taaatgggga
     2641 ggtggttaat tccgaagaat atacaggaga gattatcagg ggatttcgga tggcttatac
     2701 agaaatactg caaaatcaga aactcagaaa tatgctgaaa actttttttc agggaaaatc
     2761 cagagtaatt ttgcgacata cgcagcaata ttatatgtat ctgtttgcgt cgttccatcc
     2821 ggattatatg aaggaccgga aacaacgaga ggaacttctt caggtattgc ataaaaaagg
     2881 ggaaacccag ttgcagaaag aattaagaga ttatgaaata cagagcctgc tggaactgga
     2941 tattccatat tttgaaattg acggaaacag cagatcaatt tttgatggaa atggaaaaga
     3001 atatcaggga tatctgccat gtacacctta tgaatcatgg atagagcata tgaagcaatt
     3061 gagttgtcag gatatggagc aacaatgtga ttacatacga ttgtctatgg gattattaaa
     3121 tcatgggtat atcggcgaaa aaaatccgcg atgggcagat gaaaatactt gtatacatca
     3181 aattgcagag tggatttgca gaacagctgt aattgacgga gctgatattg gatgggctgg
     3241 actgcatttc tgggataatg gatattggag cctgaaacca tgtggtatgt atttatatga
     3301 tgggattgcg gggattgttt tgtttctggc aaaatatctg gaccggtatc aggattcgtc
     3361 atgcaggcaa gacgtggaaa aaatctataa actggctatt gaaaaattag aaaaatatac
     3421 agatctgcga tgtgaacaaa atgaagtacc tgaaccattg gcaacaggac tttacgatgg
     3481 agagagttca attgtatatg tttatctgat attatatgag atcacaggtc aggaaaaatg
     3541 gatcaagaat gctcagaagc attttgagat agtagctaaa ctgcttccaa aggatgaaaa
     3601 tatggattat ctcagtggaa atgcaggcgc aatcgtggct gccatgaaac tttatcaatt
     3661 aactggagag attgaatatt gtacagctgc ggtagaaact gaaaaagatt tatggaaaaa
     3721 aggtcagaga atggaagtgg gatatggatg gaaactgaaa aatctgaaat atccgctgag
     3781 tggactttct catggaaaca gtggcttttt gatggcgtat gtggaacttt ataaaatgac
     3841 atatgaccag gaatatctga aaaaaataaa attgttgctt tcctatgagg atatcttata
     3901 ttcagaagac ttgaaaaact ggatagatct gcgtgatccg gacggacgaa agacaatgcg
     3961 tggatggtgc catggtgctc ctgggatttt acttagccgt atgtcgataa tggatattct
     4021 gccagatgat aaacagatta aaaaggatat cctgcgggca gtatccacat tatttcacaa
     4081 tgagcgtgag aaaaaaatat gtctgtgcca tggaatgaca ggaaatcttt taattatgaa
     4141 aaagtatctg gagaagaatc cggatgatga tttaagacag aaatacgaaa ggcagttttc
     4201 gaacctgaag gaacaattgc aagatatgag aagtcttatg gttactgaga cattaaatcc
     4261 tgcatttatg aatggaataa ccggagttgg aatggcaatg atgttgctga acatggatta
     4321 gaaaaggcat ttacagcctt tctaatcagg atgtctgaaa aaataagttt ttaacagttt
     4381 ctttttctga cgattaatgt attgacggga gacatgaaga attgatgcaa tttcggaatc
     4441 tgttttatac tggtagaaaa acagagacag aattttgtat tccatacttt ggacaggaaa
     4501 gctttcgata tatgtagtta tatcataaag agtttcatcg aatggattat ctgcctgtaa
     4561 agtaagagaa cacgtatcaa agtcttctct ttcaggttct gacaaatggt atctgcataa
     4621 agctctgtaa cgattttcta tagcggtctg catatatctg acacattcac cttcggaaaa
     4681 atttttgccg ttcaggtaag gcagtgtatt aagcagagtc agatacaatt cctgtgtggc
     4741 atcgtcccgt tccatacagt ggatgcggga agcgtagctt ttgatcagag gttccatacg
     4801 tttaagaatt tcttcacctg catttttgac accagaatga taatcgtgaa ttaactgtaa
     4861 taatgacttc ataagaaact acctcctttt tggaggaagt agtcagaagt gactaaatca
     4921 gaaactgaaa atagaaaaaa tatgaattta ttgtagaaaa ataaaagaag cgaagtctga
     4981 caacagaaga aataagcttc taaaaggaat tgagttgaca aattatgaga ttttctgtct
     5041 ttctcagagg aactgaaatg ttttactact gagaaaggag gtatgaagat atggaatcca
     5101 cggttatgga aactgcaata tcgcagggaa tctgggccgt cctggcagtt tttcttttga
     5161 tttacattgt aaaatccaat gaacaaaggg atgcaaagca ggaagaaagg gaaaaaaatt
     5221 accagacagt gattgagaat ttgactgaaa aattccaaat tctaaatcag gttcagaatg
     5281 atctgaaaga gattaaggat aatcttctta ataaaaatta aataggaaaa agaaatagaa
     5341 gctctctcta caaaatgaat gtcacagtag ggagggcttt tgtcattcag gtaagaaaac
     5401 agattaattc aatatacagg caaaacactc atatccatta gaatacattt tattccagaa
     5461 ttacagaggt ttatataaat ggtgatatac tatgataata aatattattg aatggaggaa
     5521 aaagagatga aagaatacaa ggttataaca gcactttttt tgtcagcagt aatgctgggt
     5581 acagctccat taaccgtatg gggagcggag agtttttcga caggggaatc tttcagtgat
     5641 ggaacagaaa atattcctga catagtaaca gattcggctc tgtctggtga atcttctgaa
     5701 agagactatg agttaagcat agaaacaggt acggatgtag agcttacaga aagtgatttt
     5761 tatgatccgg aatttcgtgt agagaaatat gtgaaagtca gaaattcagg aaaaaaagaa
     5821 acaagagtcc gggtagatgc ttctggtctt aagaattttg aggtagatga tcagatggca
     5881 aagtggtcag aggattatga ggaacaggat tccaaaagac tgctgaagcc gggagaaact
     5941 ctggattttt ttgtactgcc aaagcaggaa tacggaacat atgatgaaac gtttgatttc
     6001 cttgcagatg acggaagcag atatccggtt catatcacaa tgaatagaga gaagaaccca
     6061 acggaaaaga agagtctgga aattaccgaa aaatcttccg agagtttccc gataatgcac
     6121 tggggatata agacacttcc ggaagccaga atttatgttt tgaaaaattt tacggacatg
     6181 gatatggaac tgtctttcga ttatagcaaa gactgtagtg tatcattatg cggaaatacc
     6241 agtctggcac ctggagagag tacagaactg agcctttgtc cgcagatggg actgccagtt
     6301 ggagaacatg atcttggagt gacagtgact gcgaaaacag cgacaggaga gactataaca
     6361 aagaagattt gggattcttt cagagtagat tcaaggacat ttcagggact ggtggatacc
     6421 attgaacctg tgaccggaat taccaatggc gtagaaaaaa ctgctgatgc tttacatttg
     6481 ccatcggttc ttaaagtcta tggtgctgaa gtggatggag aaaaaacgac attttctgcc
     6541 gatgtaaaat gggatgtgga gaattgtgca tataacccga aaaatacggc gtctcaaagt
     6601 ttcacagtta acggacaatt ggaactgcgt gaaggtgaaa acaatgaaga gctggatacg
     6661 tctgtaaaga taaaggtaca ggtggatgcg tacaaggggt tgaacagacc ggtgattgat
     6721 tcgacatgga ccagagtgat cacgaattat gcagaacttt ctttaagaga tacttctaat
     6781 gaagcagacg gatatttttt tgtagcagca gaatctcaaa aggaactgga aaaagaaaat
     6841 tatatcgcac aggtgaaggt cgcaaaatct gaactgaatc attatcctaa actgaaatat
     6901 attcctgaag ggacgcatta tctctattgc agggcatata aagaggaaag tggtcatacg
     6961 gagaaatatg gtgaatggtc tgaaggattt ctgttaaagg taaatataaa gacaccaaat
     7021 gcacctgtgg ttcaaaaact acaggtgaag aaaaatgacg ttaaaattat ccttggcagt
     7081 aatacagaag aactggatgg ttatgatgtt gttgctgcca gaagtaaaga cggggatgag
     7141 ccatcagatt atataaaggt acaatgcaaa tattcaggaa acagcaagga actcattcta
     7201 aaaggagtac cgaaaggaaa ctggtatatt ggtgtacatg gctataaata tctggatgga
     7261 tcaaataaaa aagtactgag taagtgggcg gaagttcaaa aagtaacggt aaagacaagc
     7321 cttgtaacag gaaaaccagc tgttaaatcg gcaaaggttt ccagacaggg aacaaaaaga
     7381 aaagtaacgg tgaagtttac tgtaccaaaa gcctgtgacg gaacggactg ggtactggca
     7441 aagaaagtat ctcaatccga agatggaagt tatacatatg tcagcggtta tgcttatact
     7501 aagaaaaatc agacgaaaac tacagtcatt tttaaaaatg taaaacctgg agtttattat
     7561 cttacaggac gtgcttatgt aaaaggatat gcaaaaaatt atacgaaatg gtcagaggta
     7621 aagaaagtag ttgtgaagta gaaaagtgat ttagaccaga aatttatttt ttttctgcat
     7681 atatatatat atatcaaaaa agaaggtgtt gtttgtcaga ataaataatc caaaggaagt
     7741 atggtagtat ttattctgca actgtgtggt ataaccaaaa cctgagttta cgactgtgaa
     7801 tgtacattct gcatcagatt ctttccagtt tacaacactg aaagttaatg tttctggcat
     7861 aatttttgtc tcctttaaat tttttgaatt tgcaaattca ctatataaag atgctgcttt
     7921 ggtgatttgt aaaccataag tgtgtatatg agcatgattt ttttctttca tgcggaaatt
     7981 aggtaagaat aaaaataaag attcgaggtc agatgatgca ggtttattcc ctttttatat
     8041 tttctgcatc agtttactgt aaaataataa cgggtaaaga agatataaga tgttctggta
     8101 catacaatta agaagaaagg ggcatgtgct gtgtatagtc aaaatgatga accgcctgag
     8161 atgatcaggc ggttttgaag tatctggatt ttttatgaat attttatttt taattacagg
     8221 tataatgtgt tacaataaat ataaccatta agactaccag gcaggtcaga atttgacctg
     8281 cctgtaaata aatacggaaa taaatcgggt tcaaaagaat cgttaataat tgtaacaaaa
     8341 taaaattacc ggtatggcaa aaataaaatt acaggggaaa tgcggatgaa tgagatgaca
     8401 gatgcatatg taaaactgga taaggtttcc aaaatatatg gaaccaaaga agtaaagatc
     8461 gttgcagtgg atgagatcag ctttgagatt gccaagggag agtttgtagt gatcgttggt
     8521 cccagcggtg cgggcaagac gacagtgctg aacattcttg ggggtatgga tcaggctacc
     8581 agcggagaag ttctggtgga tggaaggaat attgccagat ataacagcag gcagcttacc
     8641 ggttatcgga gaaatgatat tggatttgta ttccagttct ataatctggt gcctaatctt
     8701 acagcgctgg agaatgtaga actggcattg cagatttgta aaaatccgtt ggatgccagg
     8761 gaggttctgg aggaagtggg actgaaggac agactgacca atttcccggc acagctttcc
     8821 ggcggtgaac agcagagagt ttccattgcc agggcactgg cgaagaatcc caagctgttg
     8881 ttgtgtgatg agcccacagg tgcactggac taccagacag gtaaggcaat cctgaaactt
     8941 ttgcaggata tgtgcagaga gcgtggaatg acagtgatcg tcattaccca taactcggcg
     9001 ctgacaccta tggcagaccg tgtgatcaag atcaagaacg gcaaggtttc caggatgaca
     9061 atgaatgacc atcctacacc catagaggag atagaatggt aggtgatgaa tatgaaagca
     9121 atgcataaag atttctggat ggagatacgc aagagcaaag ccagatttat ttccatattt
     9181 atgatcgttg ctctgggagt tgcgtttttc tccgggatac aggcctcgtc accggatatg
     9241 cgcttctcag gtgatgccta ttatgatgaa accaatctta tggatatcaa agtaatggga
     9301 actctgggac tgacggagga tgatgtagct gccattaagc aggtggacgg agtagagaat
     9361 gcagagggcg cctatggtac agatgtaatg tgtggagaag gcgagaagca gaaggtactt
     9421 catgtggaag ctgtggatca aaccatgaat cggatctcag tgacagaggg aaaagctccg
     9481 gaaaaaagcg gagagatttt ccttgactgt atttttgctg agagcaatgg atataaggtg
     9541 ggtgatcaga ttaccctgaa agagggcgga ggcagcgaac tgctgaaaaa gacagattac
     9601 acagttgtgg gtttaggtga gagtccgctt tacatatcct ataaccgggg aaactctact
     9661 cttggttccg gtgaggttaa tggatttgcc tatgtgctcc ctgaggattt tgaccaggag
     9721 gtttatacac agatctatgt gcaggctcat ggggcacagg atctgatcag ctatacagat
     9781 gcttatgatt ccctgataga gcgagtgcag gagcgagtgg aggggagtga ggcagaacgg
     9841 tgtcaggtca gatatgatga gattgtagag gaagccaatg acaagcttgc agatgccaga
     9901 caggaacttg aagacggaaa gaaggaagct aatgagaagc ttgcggatgc cagacaggaa
     9961 ctggaggacg gcaaaaagaa gttaaaagac ggaaagaagg aatataagga tggcaagaaa
    10021 aagcttgcag acgcaaaaaa ggaactggag gacggaaaag cccggcttgc agatgcaaag
    10081 aaggaattag aggatggcag atcccagctt gccagtgcga aagagcagct tgccagtggc
    10141 agagcacaga tcgcatctgc aaaggaacag ctgaatgcag gatgggcgga ggtttcagag
    10201 aaccaggcaa agcttgatga tggaaaagca cagcttgagg atggcaagaa tcagttaagc
    10261 gccggtgaga agcagattgc ggatgcaaag acgcagctta cccagagcca gcaggaactt
    10321 gacaatggaa aggcgcagat tcagtcaggc agagagcaga ttgcagcaac cagacaggac
    10381 ttaaatgcca aaaaggaaag ctgcaatcag ggacttgcgc agattgagca gcaggaggcc
    10441 ggacttgcag aaggagaggc tcagcttgag ggtgccagaa gtcagcttgc agcattgcag
    10501 gcacagtatg agcaggcaca agcttcaggc acatattccg aggaagacct ggcggctctg
    10561 gcagcacagg tttccgctta tcaggagcag gtggacagtc aggcagccca gctggaagca
    10621 tccagaaacc agatcgcagc agcaagaagt gaactggaga gtggtttaag ccaggtggag
    10681 agcggactgg cccagcttga tgcaaaggaa gcagaactga accagcagga ggccgcattt
    10741 cccgatgccc aggcaaagat tgatgcagga tggaaagagg tgaaggctca ggagaagaag
    10801 ctggaaccag ccagaaaaga gattcaggaa aaagaagccc agcttgagtc agcacaggaa
    10861 cagatagatg ctgcaaaagc aaaactaaat tccagccagg cgcagttaga ggagaaagag
    10921 gcagaacttg cttcaggaga agcacagatc cgggagaatg aagggaagct tgcttccggc
    10981 gagaaagaga ttgccgacaa tgaacagaag ctgagggatg gagagaagga aatctcagag
    11041 aacgaacaga agctgaagga ttccagaaag gacatcaaga aagctgagaa ggatctggaa
    11101 gaaggtaaaa aagaatacga agacggcaag agggatgcag agaaagaaat tgcagacggt
    11161 gagaaaaaga ttcaggatgc ccgggatgag atcgatgata tcagtatgcc ggaatggatg
    11221 gtaacggacc gcaatgatct gccggaatat tcagattatg gggataatgc agacagaatg
    11281 agaagtatcg gacaggtttt ccctgttatc tttttcctgg tggctgcact ggtaagtctg
    11341 actaccatga cacgaatggt ggaagaacag agaacccaga tcggtacaat gaaggcgttg
    11401 ggatatggca agtatgcgat tgcatccaaa tatctgctgt atgcctttct tgccacagtg
    11461 ggaggcagta ttctgggaat tctgatcgga gagaagatcc tgcctttggt tattattaac
    11521 gggtatggca ttatgtacaa gggcatgatg aacaatatcc agatccgtta tgagtttaaa
    11581 tttgcaatga tagcagcagg tgcggcaact gtgtgtaccg tcggagccac cattttctcc
    11641 tgttacaggg cactggcgga aactccggca tcactgatgc gtcctcctgc tcccaaagag
    11701 ggtaagagaa tcctgctgga acgtatcccg cttttctgga aacatctgaa ttttacatgg
    11761 aaatctacac tgagaaatct tttccgatat aaaaaacgtt tctttatgac gattttcggt
    11821 atttcaggaa gtatggcgct gatgctggta ggctttggac tcagggattc cattatggat
    11881 attgccagac ggcagtatca ggaacttcag cattacacag gaacgatcat tgatgatgag
    11941 gatgctacag ataaggagag acaggaactg gatgagtttc tgaaaaataa cagtcagatc
    12001 gagagatata ctcatgtgca gtttaccaag atgagtgttc ccagaaataa atccaatatc
    12061 agcgtatatg tttatgtgcc tgagaatctt gagaccttta ataaggatgt aacgcttcag
    12121 gacagaaaga caaaagagaa gtataagctg acggatgcag gtacagtgat cagtgagaag
    12181 acggcaaccc tgacaggact gaaagtcggg gataccatga ccatcacaaa gaatggaaaa
    12241 aattatgaga caaagatcgc agcagtgaca gagaattaca tgggacatta tatttatatg
    12301 acaggaaatg tctatgaaca gaccttcggg gagaagccga actattctgc aactgtgttc
    12361 acggtaaaag aggagtacaa agaatcagaa tctgaggtgg gaaatgaaat cctgaagcac
    12421 ccggctgcat taagcatcag ctataccagc agtctggagg ctcagcttca cagaatgctg
    12481 ggggcattgg atacggtaat tgtagtgctg atcatttctg cgggaatgct tgctttcgtg
    12541 gttctgtata atctgaacaa tgtcaatatc acggagcgcc agagagaact ggcaactctg
    12601 aaggtgctgg gattctatga tactgaggtt tctgcctatg tgtacaggga gaatgttatc
    12661 cttactctca tcggcgtgct ggcaggagct gtattcggaa tctttttgca caggtatatt
    12721 atccgtactg tggaagtgga tgcggttatg ttcggaagaa atattaatcc tgtcagtttc
    12781 ctgtactgcg gactgctgac aattggattc tccatgatcg taaatctgtt tatgcatcag
    12841 aaattaaaga agattgatat ggtagaatcc ctgaaaagtg tggaataaac gatctgtcgc
    12901 tttattgcgg aaaagaagaa attgtttttc tgtggttttt aaatatgtag tcaaacggat
    12961 agaatggata agaggaagaa aggggaatat tatcatggga acagcaaatc agatagagca
    13021 ggaattaatg agctatatat ccgatcataa aatcaggaac acgcattcac atcatctgcc
    13081 ggaacaggcg atggtggatt ttgatctgga taagctgata aataatacgt atttacaatg
    13141 gcagcaggta actccgggga caacagcaga aagcagaact gcatatctgg aaaaaacacg
    13201 atataaatct tattttgtct ggcttcaaaa ggcaatcggg gagttgtatg gaatatcgga
    13261 gccgatcaca gctcagaact ggaatcagat ttcagatcag atcagaaaag cgcatcaaaa
    13321 tcccgacttt tacatggatg tgctgaaaaa taagtgtaag tatcaaaaag taatcgtaga
    13381 tacctactgg aatccgggct ctgacaatgg aagaccggaa ctgtttacgc ctgcttttcg
    13441 actggatctg ttctttttgg gctataaaaa aggacttcgc aatcatgacg gtgtatcact
    13501 ggaagagaac ttcggtgagc taccggacaa tttacaggat tatgtggagt gggtcagaaa
    13561 gtggatcata caaaaaaaga gtgagggctg tgtggcctta aaaatagcga tggcctacga
    13621 gcgtagtctt cattttgaaa aagtgacgcg ggagcaggct gaaagggtat tccgtttaca
    13681 agagtcggat ataacccagg aggatatcag atgttttcag gactatttgt tctggaaaat
    13741 atgtgaaatt gcggcggaag tgtcacttcc attgcagtgc catacaggaa tgggacaagt
    13801 catagatacg aatatattgc agttgaacaa tgtgataaaa aataatccgg aaacaaaatt
    13861 cgtactgctg cattgcggct ttccatgggt agatgatctc ttttccatag tagacggata
    13921 tccgaatctg tatccggatc tgacctggct tccaatctta tcctacactg catcaaaacg
    13981 tgtaatgcat cagctgatcg agatgtccca gattgataaa atctgctggg gatgtgatac
    14041 atggacagta gaggaaagtt atggctccct tcttgcattc cgtttttcac tgtgcagtgt
    14101 tctgagagaa aaaatagagg acggatatct ttccgtaaat aatgcaaagg atattattga
    14161 taaaattttg ttcgacaatg cgggaaaaat atacgtatga caccagaaag gaggcggaag
    14221 tatccatgaa ttcaacaatt tccattggaa tgcaggattt tggtaagctg atcagaagtg
    14281 gtgtgtttta tgtggataag acgtctttta tcaaagaatg g
//
