LOCUS       c00112_gnlPro..        15916 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MDLEHPFK_112.
ACCESSION   c00112_gnlPro..
VERSION     c00112_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 00:47:00
            Original ID  :: gnl|Prokka|MDLEHPFK_112
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15916
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15916
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2901:5916]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2902..5916
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15916
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15916
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             841..2496
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg112_1"
                     /sec_met_domain="HMGL-like (E-value: 3.5e-76, bitscore:
                     247.5, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNPSKYQRQYFMPPVKCMKWAEKEYVDKAPAWCSVDLRDGNQAL
                     VIPMSLEQKIEFFKLLVKIGFKEIEVGFPAASETEYEFLRTLIEQNLIPQDVTIQVLTQ
                     AREHIIRKTFEAVKGAPKAIVHVYNSTSVAQREQVFKKSKEEILKIAVDGAALLKKLAD
                     ETEGNFQFEYSPESFTGTEPEYALEVCNAVLDVWQPTADNKCIINLPVTVQHSMPHVYA
                     SQVEYMCENLKYRENVIVSLHPHNDRGCGVADSEMGLLAGADRIEGTLFGNGERTGNVD
                     IVTLGMNMYSQGVDPKLDFSDMPHICEIYEECTGMKVGERSPYSGALVFAAFSGSHQDA
                     IAKGMHWRDDKDPDHWNVPYLPIDPTDVGRNYDADVIRINSQSGKGGVGYILETKFGLN
                     LPPKMREAMGYATKAVSDHKHKELHPDEIFNLFKQTFENITEPYSINEVHFQQKDGGIV
                     TKVTSTFRGKTITTEASGNGRLDAVSNALKKAYELKYSLETYQEHALERSSSSKAIAYV
                     GIKKPDGTLAWGAGVDADIIRASIDALVTAINNR"
     CDS             2902..5157
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg112_2"
                     /sec_met_domain="Gly_radical (E-value: 3e-41, bitscore:
                     131.6, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 6.1e-268, bitscore:
                     881.3, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKNFEQWNGFKGNRWKEKIDVRNFIGMNYTPYDGDASFLEGPTEA
                     TNKLWGKLQALQKEERAKGGVLDMETEVVTSLTAYGPGYIDEETKDLEKVVGLQTDKPL
                     KRAFMPYGGIKMAEQACETYGYKVSDKIKDVFHNYEFKTHNQGVFDIYTPEMKVARHNK
                     ILTGLPDTYGRGRIVGDYRRVALYGIDALIEGKQKDFAACDRQGMRRYDFQLREEIADQ
                     IRALKGMKVMAESYGYDISKPAKDAREAFQWLYFGYLAAIKTQNGAAMSVGRISTFLDI
                     YIERDLQNGTLTEKEAQELVDHMVMKFRMVKFARIPSYNQLFSGDPVWATLEVAGMGQD
                     GRSMVTKNDYRFLHTLEDMGPAPEPNLTVLYSSRLPENFKKYAANISVTTSSVQYENDD
                     VMRPVWGDDYSICCCVSATETGKEMQFFGARANLAKCLLYAINGGVDEKTKQQVGPNYQ
                     PITSEYLDYDEVIAKYDKMMDWLAHLYVGTLNMIHYMHDKYYYEAAEMALIDTKVERSF
                     ATGIAGFSHVVDSLSAIKYAKVKAIRDEDGITTDFQVEGDFPRYGNDDDRADEIATTLL
                     STFLEKLKHIHTYRDSKPTTSILTITSNVVYGKATGSLPDGRKAGEPLAPGANPSYGAE
                     QNGLLASLNSVAKLDYEDALDGISNTQTINPDALGHSDDERSENLVHVLDGYFDQGAHH
                     LNVNVFGKEKLIDAMEHPEKEEYANFTIRVSGYAVKFIDLTREQQLDVIARTCHDRM"
     CDS             5176..5916
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 84; E-value:
                     3.9e-26)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg112_3"
                     /sec_met_domain="Radical_SAM (E-value: 2.3e-27, bitscore:
                     87.7, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDNKQIKGYVHSLESFGSVDGPGVRYVIFLSGCAMRCQFCHNPDT
                     WKMKQGELYTADELLKKALRYKGYWGSKGGITVSGGEPLLQMDFLTEFFKKAKAEGVHT
                     NLDTSGNPFTDQEPWHSGWLELMKYTDLVMLDIKQIDEQEHIKLTGHSNKNILAMAREL
                     SDMKKPVWIRHVLVPDGSDKDEYLHRLADFIHTLSNVERVEVLPYHTLGKFKWENLGLS
                     YPLEGVNPPTQERIDNARKILGAI"
     CDS             6380..8893
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AstE_AspA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg112_4"
                     /sec_met_domain="AstE_AspA (E-value: 1.3e-32, bitscore:
                     104.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDLLSEIESYWTTRAEGYSEVNHKELNGMQKGAWLEVLKGQFPE
                     KAKDEIKILDIGTGPGFFPVILAEAGYKVTAVDYTQEMLDTAKRNAGNLCERISFYKMD
                     AQNLEFEDDVFDVVISRNLTWNLKDPKRAYEEWCRVLKPGGKLLNFDANWYGYLYDEEK
                     RLSYEEDRKSVESEHLDDHYLCTDIDRMEKIALQMPLSSINRPSWDRKFLKENGFESVA
                     VDTGIWQRVWSQEEKLNYHSTPMFMISAVKEEKNVWSENDGMGDSDSGYDRKRDLEDAM
                     LCAAPGMKKNGFLRLGGGEFSLPYTVICGSHPGKTVLITAAVHGGEYVGIQAAVELADK
                     LKPEKIHGRVILVKTVCRKEFEERSGSVCPEDEKNLNRVFPGNPQGTRMDRLAYEVVQK
                     LHSAADYYIDLHSGDDYEQLTPYIYYAGCADEDVVQMSRKMAEQADVPYMVKSNVASGG
                     SYNYAAACGIPSVLIERGQMGGWSPEEVHSTRKDVRNILCALGVYDGMRSYSNYYPMEI
                     EDVRYQSASVSGLWYPAKKPGDIIKVGEYLGCVKDYERNILETSLSDLNGVVLYQTGSL
                     QVIKDGPMIAYGSFSRRKDERKKKITNYWAKRSDSFMEQRRAELHSDMADKWLKEIGTF
                     LPDGKLRILDVGCGAGFFSILLAKLGHEVTGIDLTPDMIIHSRELAKEENASCTFEVMD
                     AENPDFPDGTFDVIVSRNLTWTLPDAARAYKEWIRVLKTGGILINADANYGADDFSDTA
                     DLPANHAHFTVGDAMMQECEEIKRQLPISSYVRPAWDLETLGKLGINRFSIDLGISSRI
                     YTKKDEFYNPTPMFLICGEKNKCNN"
     CDS             9089..9925
                     /locus_tag="ctg112_5"
                     /transl_table=11
                     /translation="MKVQKKESKQSGNPARSLILVTVCTCTAIAFAAGGRIADFNGKNK
                     VYAASENREKTFSSDADETDVLPTGIAGVVSGMNDTASPKKSVTRIGTSCEQVMVGQRI
                     KVIEDNMAEFDVSSSMESSINELDARTAALAESARMMSDEDYDTLLHIVEAEAGTEDVK
                     GRILVANVIMNRIKNKEFPDTVTEVVWQNTNGVPQFSPTYDGRINEVTVTDETREAVRQ
                     ALEGVDYSEGALFFIQKSEAESQNVSWFEKDLKRLFKYGVHEFYTYPDSAESSTGS"
     CDS             10209..11699
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg112_6"
                     /sec_met_domain="PALP (E-value: 2e-17, bitscore: 54.7,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVLYKSTRGKEETVTASMAILKGLSEDGGLFVPTEIPKLDVPMD
                     ELAKMSYQETAYEVMKCFLTDFTEEELKNCINNAYDEKFDTKEIAPLHEADGAYFLELY
                     HGATIAFKDMALSILPHLMTTAAKKNQVKNEIVILTATSGDTGKAAMAGFADVPGTKII
                     VFYPKHGVSPIQEKQMVTQKGNNTYVVGITGNFDDAQTAVKKMFNDKELEAELDAAGYQ
                     FSSANSINIGRLVPQIVYYVYAYASLVRQGKIKDGQEINVVVPTGNFGNILAAYYAKQM
                     GLPVHKLICASNDNKVLYDFFRTGTYDRKRDFILTTSPSMDILISSNLERLIYRIAGGD
                     AKKCAELMQSLTAGGEYTITEDMKAQLADFYGNYCTEDETAKTIAEIFKDSHYVIDTHT
                     AVAAGVYDKYVKDTNDTTPTVIASTASPYKFTRSVMEALGADTDGKDDFALADELSALS
                     GVKLPQAVETIRTAPVLHNRVVNAPDMPKAVKDILGIR"
     CDS             12051..13112
                     /locus_tag="ctg112_7"
                     /transl_table=11
                     /translation="MSVSERKFGVLQTGETVKIFHLENKSGAYAEVTDFGAILVKVCVP
                     DKDGTLTDVVLGYDDLASYEVNGCFFGSTIGRNGNRIGGAKFSVNGKEVVLVQNENDNN
                     LHSGPDGFEKKLWKVAEISDDKNSVIFNRISPDGENGFPGEFDVSVKYEFTEDNELKIH
                     YQGICDEPTVANMTNHSYFNLNGEGSGTAMDQYLTIHAKYYTPVANSHSIPTGVYEEVA
                     GTPMDFRTAKQIGQDIEAEFDQLKFTGGYDHNYVTDNYAKGNRRLIATAYSDKTGIAMN
                     VTSDCPCVQFYAANFVENEHGKNGHTYNKRDAFCLETQVEPNAVNVEDFHSPILNAGEQ
                     YDSVTAYHFYIRK"
     CDS             13344..14240
                     /locus_tag="ctg112_8"
                     /transl_table=11
                     /translation="MKKKNKTRSVTGLLFGFMERVSGDHVGAYATQAAYFLIMSFIPCI
                     LFLTTLVRYTPLTYNVVRDAIVAFIPENLQSFVLGIVVDVYKRSTAIVPLSAIVALWSA
                     GKGMQSIINGLNTIYHVKETRNWLLTRIYAVFYTLSLVIAVIVSLLMLVLGNEIQKVVS
                     RYIPFLGRVLGKILGARALLVFGVLFLVFLMLYKVLPNRKATFKSQIPGALIIAVAWSI
                     FSYGFSFYFEIFPGFSNMYGNLATIIMVMVWLYICMNLLLYGAEINAYFEKEFRIAHKS
                     VQELLAHEKEKKQQENE"
     CDS             14233..14346
                     /locus_tag="ctg112_9"
                     /transl_table=11
                     /translation="MNEFWLLLFTGNIPRGVFCERRSQKTRDILREFMRLA"
     CDS             14503..15381
                     /locus_tag="ctg112_10"
                     /transl_table=11
                     /translation="MIVVYLIFLAVIQAVTEFLPVSSLGHLCILEQYMGIGHETGLLSE
                     TMLHLGSAAAIIFLFRKDLKKIGLGLLGMFMDMIGNLNLYIHNKKTGESLGYARIVTGT
                     YRKTGALLVISMIPTALLGLTGKRLALLAADSQIVPGIGFLLTGVFLLVTDLNKSGGKK
                     GPREASYDSAMWIGICQGIAVFPGISRMGFTLCAALLCGYNRKFAVRFSVFMSLPAIIG
                     AFFTEIGNFGASEMTAGLGFTYVFAMIIAGFAGCLVIRNTIAMTQNIKLRYFAYYSFIV
                     GIITLALNFAL"
ORIGIN
        1 cagctttagc aataagaggg atagaaccca actggctgtt ggggtatcta aaccctacac
       61 ttatatatta ggaggagaat aaggaaactc gagagaaagt ttttgaactg gatatgcgtg
      121 tagacaattt ggaaaaagcc atcatgccag cgtaactgta acagatgatt gtaaggcttg
      181 tacataggat aaacaggaag aaattttata acataaaaaa gtacatgaaa tttcttcctg
      241 ctaaatttgt ataatttttg taaatttttc aaaaaacagt tgaaatcaca gaaataattt
      301 gttatactaa cttgcgttac ggggtatggc gtagcttggt agcgcgcacg gctgggggcc
      361 gtgaggtcgc aggttcaaat cctgttgccc cgactgacat atggttaaat cgtttgtagt
      421 atatttacaa tgaatgattc agacgtatgt tcatttcaaa aaagccaaat aaagttataa
      481 gtaaaatgca atgataagga atagtacacc cggaccggag cacagagaac tgctggttgc
      541 tgagaagcag tggaaggaaa ttgtggaact cgcctttgag cagctgtctg aaattataca
      601 agagtaggtg cagacggttt ccaccgttat atggagagga tataagaata ccggatatcc
      661 ggagattccg tatcccatga gtgtatgaca ttgttcataa ataagagtgg taccgcgtaa
      721 gatgataata tctttcgtct cttgcagata agtctgtgga gatggaagat tttttttatg
      781 tctttttaca gtcaatcccc acagtccaaa cataatattt acataacgga ggaagaaaaa
      841 atgatgaatc caagcaaata tcagagacag tattttatgc cgcctgttaa atgcatgaaa
      901 tgggcagaaa aagaatatgt ggacaaagca cctgcctggt gttctgtaga ccttcgtgac
      961 ggtaatcagg cactggtgat tccgatgagt ctggaacaga aaattgaatt ctttaaactt
     1021 cttgtaaaaa tcggtttcaa agaaattgaa gtaggtttcc cggctgcttc tgaaacagaa
     1081 tatgaatttc tgcgtaccct gatcgagcag aatctgattc cacaggatgt gactattcag
     1141 gttctgactc aggccagaga gcatatcatc cgcaaaactt ttgaagctgt caaaggcgca
     1201 ccgaaggcaa ttgtacatgt gtacaattcc acctctgtag ctcagagaga acaggtattt
     1261 aagaaatcca aagaagaaat cttaaagatt gcagtggatg gtgccgcatt attaaagaaa
     1321 ctggctgatg aaacagaagg aaatttccag tttgagtaca gccctgaaag cttcacaggc
     1381 acagaaccgg aatacgctct ggaagtatgc aatgcagttc ttgatgtatg gcagcctaca
     1441 gcagataaca aatgcatcat caatctgcct gtaactgtac agcattctat gccgcatgta
     1501 tatgcaagcc aggtagaata tatgtgtgaa aatctgaaat accgcgagaa tgtaatcgta
     1561 tctctccatc cacacaatga cagaggatgc ggtgttgcag attctgaaat gggattactt
     1621 gcaggtgcag acagaatcga gggtactctg ttcggaaacg gtgagcgtac cggaaacgta
     1681 gatattgtta cacttggtat gaatatgtat tctcagggtg tagatccaaa acttgacttc
     1741 tccgatatgc cgcatatctg tgaaatatat gaagaatgta ccggaatgaa agtaggcgaa
     1801 agaagtccgt acagtggtgc acttgtattt gccgcatttt ccggctctca tcaggatgca
     1861 attgccaagg gtatgcactg gagagatgac aaggatccgg atcactggaa tgttccgtat
     1921 cttccaatcg acccgacaga tgtgggaaga aattatgacg cagatgttat ccgcatcaac
     1981 agccagtccg gtaaaggcgg cgtgggatat atccttgaga ccaaattcgg tctgaacctt
     2041 cctccgaaaa tgcgtgaggc aatgggatat gccacaaaag ctgtttcaga tcacaaacat
     2101 aaagagcttc atcctgacga aattttcaat ctgtttaaac agacctttga gaatatcaca
     2161 gaaccgtaca gcatcaatga agtacatttc cagcagaaag atggtggtat tgtaacaaaa
     2221 gttacctcta ctttccgcgg gaagacaatc actacagagg catccggtaa cggacgtctt
     2281 gatgcagtca gcaatgcact gaagaaggca tatgagctga aatattccct ggaaacatat
     2341 caggaacatg cgctggagcg cagttcaagt tccaaagcta ttgcttatgt cggtatcaaa
     2401 aagccggatg gaactcttgc ctggggtgca ggcgtagacg cggatatcat tcgcgcatct
     2461 attgatgcac ttgtaacagc gatcaataac cgttagactg ttccgacacg ctcgattctt
     2521 tcctgctgtt ttttgacttc tgcaggtcag gctaatatcc gcttggcagg gaataatata
     2581 gtttacataa aatatcaaaa atcagatacc ggtcagattg tccagaggac ttcctgaccg
     2641 gtattttttt gtatttataa aaatacaaga aagtcttaat gtacgcgata aagtacaata
     2701 aagaagcaaa ctccgatgaa aagctatcag aattgtattt aattaaaatc ataagggaaa
     2761 ttaattgaca taacactcat gtttacgtat actgacagcg tgggcagaaa agtgtcctaa
     2821 ataagtacaa tttacatttt attatctcac tccaggccag tgagaaatgc gcggaaatat
     2881 tttagagaaa gaggtaaaag aatgaaaaat ttcgaacagt ggaatggctt taagggcaac
     2941 cgttggaaag aaaaaatcga tgtacgtaac tttattggaa tgaactatac accatatgac
     3001 ggtgatgctt ctttcctgga aggacctaca gaagctacaa acaaactgtg gggcaagctc
     3061 caggcacttc agaaagaaga acgtgccaaa ggcggagttc ttgatatgga gacagaggta
     3121 gttacatctc tgacagcata tggtcccgga tatattgatg aagaaacaaa agaccttgaa
     3181 aaagttgttg gtcttcagac agataaacct ctgaaacgtg ctttcatgcc atacggcggt
     3241 atcaaaatgg cagagcaggc ttgtgaaact tacggatata aagtaagtga caagattaaa
     3301 gatgttttcc acaactatga atttaaaact cacaaccagg gtgtatttga tatctacaca
     3361 cctgagatga aagtagcacg tcacaacaag atccttacag gtcttccgga tacttacgga
     3421 cgtggacgta tcgttggcga ctacagacgt gtggctctgt acggaatcga cgctctgatc
     3481 gaaggaaaac agaaagactt cgcagcatgc gaccgtcagg gtatgagacg ttatgacttc
     3541 cagcttcgtg aagagatcgc tgatcagatc cgtgctctga aaggcatgaa agttatggct
     3601 gaatcttatg gatatgatat ctccaaaccg gccaaagatg caagagaagc tttccagtgg
     3661 ctgtacttcg gatatcttgc agccatcaaa actcagaacg gtgctgcaat gagtgtcgga
     3721 cgtatttcta cattccttga tatttatatt gaaagagatc ttcagaacgg aactcttaca
     3781 gagaaagaag ctcaggagct tgttgaccac atggtaatga aattccgtat ggttaaattt
     3841 gcacgtatcc cttcttacaa tcagttattc tccggtgacc cggtatgggc aactctggaa
     3901 gtagcaggta tgggacagga cggacgttcc atggtaacaa agaacgacta tcgtttcctg
     3961 cacacactgg aagatatggg accggctccg gaaccaaacc ttacagtact ttattcttca
     4021 agactgcctg agaacttcaa gaaatatgct gcaaatattt ctgttacaac aagttctgtt
     4081 cagtatgaga atgatgatgt tatgcgtccg gtatggggcg atgactacag catctgctgc
     4141 tgtgtatctg ctacagagac aggtaaagag atgcagttct tcggtgctcg tgcaaacctt
     4201 gcaaaatgcc ttctttatgc gatcaacggc ggtgttgatg agaagacaaa acagcaggta
     4261 ggaccaaact atcagccgat cacttctgaa tatcttgact atgatgaagt aattgcaaaa
     4321 tatgataaaa tgatggactg gctggctcat ctgtatgtcg gaacactgaa catgattcac
     4381 tacatgcatg acaaatacta ctatgaagca gcagagatgg ctctgatcga tacaaaggtt
     4441 gagcgttctt tcgcaacagg tatcgcagga ttctctcatg tagtagactc cctgtccgct
     4501 atcaaatatg caaaagttaa agctatccgt gatgaagacg gtattacaac agatttccag
     4561 gttgagggtg acttcccacg ttatggtaat gatgatgaca gagcagacga gattgcaaca
     4621 actcttctgt ctacattcct tgagaaactg aaacacatcc atacttatcg tgattccaag
     4681 ccaaccacat ctatccttac tattacttcc aacgttgttt atggtaaggc tacaggatct
     4741 cttccggatg gaagaaaagc aggggaacct cttgcacctg gcgcaaaccc atcttacggt
     4801 gcagagcaga acggtcttct tgcttccctg aactctgttg ccaagcttga ctatgaagat
     4861 gctcttgatg gtatctccaa tactcagaca atcaatcctg atgctctggg acacagtgat
     4921 gacgagcgtt cagagaatct ggtacatgta cttgacggat actttgatca gggtgctcat
     4981 cacctcaatg taaacgtatt tggtaaagag aaactgattg acgctatgga acatccggaa
     5041 aaagaagagt atgcaaactt cacaatccgt gtatccggat atgctgttaa gttcatcgac
     5101 cttacaagag agcagcagtt agacgttatt gccagaacct gccacgacag aatgtaatta
     5161 atggatgatg atataatgga taataaacag ataaaaggct atgttcattc tttagaaagc
     5221 ttcgggtccg ttgacggacc cggagtaaga tatgtgattt ttttaagcgg ctgtgccatg
     5281 agatgtcagt tctgtcataa tccggatacc tggaagatga agcagggaga gctttatacg
     5341 gcagatgagc ttcttaagaa agctttacgt tataagggct actggggcag caaaggcggt
     5401 atcactgtaa gcggtggtga gccattgctt cagatggatt ttcttacaga attttttaag
     5461 aaggcaaagg cagagggtgt gcatacgaat cttgatacca gtggaaatcc cttcactgat
     5521 caggaaccat ggcattccgg atggctggag cttatgaagt atacagatct tgtaatgctt
     5581 gatatcaagc agattgacga gcaggagcat attaagctta ccggtcattc caataagaat
     5641 attcttgcga tggcgcggga actttctgat atgaaaaaac ctgtatggat ccgtcatgtg
     5701 cttgtgccgg acggaagtga taaggatgaa tatctgcacc ggttagctga ttttatccat
     5761 actctttcca atgtggagag agtggaggtg ctcccttatc atacgcttgg taagtttaaa
     5821 tgggagaatc tggggctttc ttatccactg gagggggtta atcctccgac gcaggaaagg
     5881 attgataatg cccggaagat tcttggagct atctgagtaa aaatatatag ctgtcatatc
     5941 ctctttttgg ggtatggcag ctttatttgt ttaaaaaagg gacgcgaagc aggcgtatag
     6001 ttgtaccgga tacggtttcg gtatctaaga gattctaagc cctcgaaaat ccgctaaaag
     6061 catgagacga aaagtccgga attactcgct gtcgctcaga caagggactt ttcgtctcat
     6121 aacgcagatt tccgaggact aagaatctct aagatgcctg caaatgcatc cggtacaact
     6181 atacgcctgc ttcgctggtt ttggttaata tataaataca aggcgaagtg tgaaaaagtt
     6241 ttaagaagga ctttgtttat gcaaaaatga attgagatgt gaaatatatc ccccgggagg
     6301 gcttgttgga aaggggaggg atttgatata attttggcta tatatgatta taaattgcgt
     6361 gcatggaggt tggcataagg tgaaggattt attatcggag attgagagtt actggactac
     6421 ccgggctgag gggtattctg aagttaatca taaggaattg aatgggatgc agaagggggc
     6481 atggcttgag gtgttgaaag ggcagttccc ggagaaagcg aaggatgaga ttaagatttt
     6541 ggatatcgga acaggacctg gattttttcc tgttattctg gctgaggcgg gatataaggt
     6601 gactgctgtt gattatacgc aggagatgtt ggataccgcg aagaggaatg ccggtaatct
     6661 ttgtgagcgg atttcttttt ataagatgga tgctcagaat ctggaatttg aggatgatgt
     6721 gtttgatgtt gtgatcagca ggaatctgac atggaatctg aaggatccta agagagctta
     6781 tgaagagtgg tgtcgtgtac tgaaaccggg cggaaagctt cttaatttcg atgcaaactg
     6841 gtacggttat ctttatgatg aggagaaacg cctgtcttat gaggaagacc gaaagagtgt
     6901 ggagagtgag catctggatg atcattacct ctgtacggat attgacagaa tggagaagat
     6961 tgcactgcag atgcctcttt cttctattaa cagaccgtcc tgggacagga agtttctgaa
     7021 ggagaacggg tttgaatctg tggcagtgga taccggaatc tggcagcggg tgtggagtca
     7081 ggaagagaag ctgaattatc attctacgcc gatgtttatg atcagcgctg tgaaggaaga
     7141 gaaaaacgtc tggtccgaga atgatggaat gggtgattct gatagcggat atgacaggaa
     7201 aagagatttg gaggatgcca tgctgtgtgc tgctccgggt atgaaaaaga atggatttct
     7261 gagactgggc ggaggtgagt tttcgcttcc ttatacagta atctgcggtt ctcatcccgg
     7321 aaagacagtt ctaatcaccg ctgcggtcca tggaggagaa tatgtgggaa tccaggctgc
     7381 tgttgagctt gcagataaac tgaagcctga gaagatccat ggaagagtaa tcttggttaa
     7441 gactgtgtgc aggaaggaat ttgaggagag gagcggcagt gtctgcccgg aggatgagaa
     7501 gaatctgaat cgtgtatttc cggggaatcc gcagggaacc aggatggacc gtctggcgta
     7561 tgaggtggtt cagaagcttc acagtgcagc agattattat attgatcttc acagcgggga
     7621 tgattatgag cagcttacgc cttatattta ctatgccgga tgtgcagatg aagatgtggt
     7681 tcagatgtca aggaagatgg cagagcaggc agatgttccc tatatggtaa agtctaatgt
     7741 ggcatccggt ggttcttaca attatgctgc cgcatgtggc attcccagtg ttctgatcga
     7801 acgtggccag atgggaggct ggagtccgga ggaggttcat tctacaagaa aagatgtgcg
     7861 taatattctg tgtgcgctgg gtgtttacga tggcatgaga agttacagta attattatcc
     7921 catggaaatt gaagatgtgc gttatcagtc tgccagtgta tccgggctgt ggtatcctgc
     7981 caaaaaaccg ggagatatca ttaaggttgg agagtatctt ggctgtgtta aggattatga
     8041 gagaaatatt ctggagacaa gtttatccga tttaaatgga gtggttctat atcagacggg
     8101 aagtcttcag gttattaagg atggtccgat gatcgcatat ggcagtttca gcagaagaaa
     8161 ggatgaacgc aagaaaaaga tcacaaatta ctgggcgaaa agaagcgaca gttttatgga
     8221 acagagaaga gctgagcttc acagtgatat ggctgataaa tggctgaaag agatcgggac
     8281 ttttcttcct gatggaaaat taaggattct ggatgtggga tgcggtgcag gcttcttttc
     8341 cattctttta gcaaaactgg gacatgaagt tacaggaatc gatctgacac cggatatgat
     8401 cattcattcc agggaactgg caaaagaaga gaacgcctcc tgtacgtttg aagtaatgga
     8461 tgcggaaaat ccggattttc ctgatggtac ctttgatgtg atcgtgtcca gaaatcttac
     8521 ctggacactt ccggatgcag caagagcata taaagaatgg attcgtgtgc tgaaaacggg
     8581 aggaatcctg atcaacgcag atgccaatta tggtgcagat gatttctcag atactgctga
     8641 tttgcctgcc aatcatgctc attttacagt aggcgatgcc atgatgcagg aatgcgagga
     8701 aattaaacgt cagcttccta tcagttccta tgtacgccct gcctgggatc tggagacact
     8761 gggaaaactg ggtatcaaca gattctccat tgatctgggt atcagcagca gaatttatac
     8821 aaagaaagat gagttttata atccaacccc tatgttcctg atctgcggcg aaaaaaataa
     8881 atgtaataat tgagaaaaat gaagcatata ttaaagggag atttcattga tggagccttc
     8941 ctttttttct tttttgcaag ctaaaatgtt acaaaaatat gaaaaaagct tgacaaaatc
     9001 aattatatta aatataattt tcttataagt tacagaaatg ttacaaccat aaaaacctgt
     9061 aattaaaaaa actcaaggaa tgataagtat gaaagttcag aaaaaagagt caaaacagtc
     9121 cggcaatccg gcgcggagtc tgatactggt tacagtgtgt acctgtacgg cgattgcgtt
     9181 tgcagcaggc ggcagaatag cagattttaa tggaaaaaac aaagtatatg cagcttctga
     9241 aaatagggag aaaacttttt cctctgatgc tgacgaaaca gatgtactgc caacaggaat
     9301 tgcaggagta gtatctggaa tgaatgatac agcttctccc aaaaaatcag tcacacgtat
     9361 cggaacttcc tgtgaacagg taatggtcgg tcagagaatc aaagttattg aagataatat
     9421 ggcagaattc gatgtcagct cttctatgga gagcagcatc aatgagttag atgcaaggac
     9481 agcggctctt gcagagagtg cccggatgat gtcggatgag gactatgata cattgcttca
     9541 tattgtagaa gctgaagcag gtactgagga tgtcaaggga cgcattctgg ttgccaatgt
     9601 gatcatgaac cgtataaaga ataaggaatt tcccgataca gtcacagaag tggtatggca
     9661 gaataccaat ggtgttccgc agttttcgcc gacttatgac ggacgtatca atgaagtaac
     9721 tgttacagat gagacaagag aagccgtcag acaggctctt gaaggtgtgg attattcaga
     9781 aggagcactg ttttttatcc agaagtctga agctgaaagc cagaatgtct cctggtttga
     9841 gaaagatctg aaaaggctgt ttaaatacgg cgtacatgaa ttttatacct atccggattc
     9901 agcagaaagt tccacaggat cgtaataaac gatactcttc atataactca tttaacagga
     9961 ttgcggtaat actgctcaaa atatggacat attcttcggg aacaaaagaa tatgtccata
    10021 tttttgattt atagtaatca atcataaaaa gacagaaaaa agagaaataa tttaggatag
    10081 tattttgcta aagtatatgc tataatgtgc tcaattggcg aaatgaataa ctgtaactgt
    10141 tcagcggttt attattactg ccaatatact gaacagttac gaataacttt ggaaaggcag
    10201 gaaatatcat gcaggtatta tacaaaagca caagaggaaa agaagaaacc gtaacagctt
    10261 ctatggctat tttaaagggg ctttctgagg atggcggctt atttgtgccg acagagattc
    10321 cgaagctgga tgtcccaatg gatgagctgg caaagatgag ctatcaggag acagcatatg
    10381 aagtaatgaa atgtttcctt actgatttta cagaagaaga attaaagaac tgcatcaaca
    10441 atgcctatga tgaaaaattt gatacaaaag agattgcacc gcttcatgaa gcagacggag
    10501 cttatttcct tgagctgtat catggtgcga ccattgcgtt taaggatatg gcattatcaa
    10561 ttcttccaca tcttatgact acagctgcta agaagaatca ggtaaaaaat gagattgtta
    10621 ttcttaccgc tacttccgga gatacaggta aagcggcaat ggccggattt gcagatgttc
    10681 cgggaaccaa gatcatcgtt ttctatccga aacatggtgt aagtcctatc caggagaaac
    10741 agatggtaac tcagaaaggc aacaatacat atgttgtggg aattaccgga aactttgacg
    10801 atgcacagac tgccgtaaag aaaatgttca atgataagga actggaagca gaacttgatg
    10861 ctgcaggata tcagttctca tctgcgaact ctatcaatat tggacgtctg gtaccgcaga
    10921 ttgtttatta tgtatatgca tatgcatcac ttgtacgtca gggcaagatc aaagacggtc
    10981 aggagatcaa tgtggtagta cctaccggaa actttggaaa tatcctggct gcttattatg
    11041 caaaacagat gggacttccg gttcacaaac ttatctgtgc ctccaatgat aacaaggttc
    11101 tgtatgattt cttccgcaca ggaacttatg acagaaagcg tgactttatc cttacaacct
    11161 caccgtccat ggatattctg atctccagca atctggaacg tctgatctac cgtatcgcag
    11221 gcggtgatgc aaaaaaatgt gcagagctga tgcagtctct tactgctggc ggcgagtata
    11281 ccatcacaga agacatgaag gcacagcttg cagacttcta tggcaattac tgtacagaag
    11341 acgaaacagc aaaaacaatc gcagaaatct tcaaagacag tcattatgtg atagataccc
    11401 atactgcagt tgcagcaggt gtttatgaca aatatgtaaa agataccaat gataccacac
    11461 caactgtcat tgcatccaca gcaagcccat ataaatttac aagaagtgta atggaagcac
    11521 ttggagcaga tacagacggt aaggatgatt ttgcactggc tgatgaactg agtgcgcttt
    11581 ccggagtgaa acttccacag gcagttgaga cgatccgcac agcaccggtg cttcataacc
    11641 gggtggtaaa tgcgccggat atgccaaagg cagtaaaaga tatccttgga atccgataat
    11701 ctccatatta taaaaaatat aattaattct acattttatg ttgaaaaaga acatatactg
    11761 gagtataata aaaatcagtt aaaaacagtg aatatcctga aatgtacgag gccccttctt
    11821 tttttgaacc tacatcgact ttaacgggaa cccaacatcg caggccggat gtcaggccgt
    11881 cattatgcag cggaagacag aaggtctgtt gaggataccc acctagctac ggctaggcgt
    11941 caatgggaag ggaacggcat ttcgggaact gtaaaaatga gccgtagaga ggctcttttt
    12001 tattatcttt tggatttaat attattttat gatacgggag gttggaaaca atgagtgttt
    12061 ctgaaagaaa gttcggtgta ttacagactg gggaaacagt aaaaattttt catctggaaa
    12121 acaaatccgg ggcatatgcg gaagtgacag attttggagc aatcctggtt aaggtctgcg
    12181 tacctgataa agatggtact ttaacagacg tagtacttgg atatgatgat ctggcatctt
    12241 atgaagtaaa tggatgcttt ttcggttcaa ccatcggcag aaacggaaac cgcatcggcg
    12301 gtgcgaaatt ctctgtcaat ggtaaagaag tagttcttgt tcagaatgag aatgacaata
    12361 atcttcacag cggtcctgac ggatttgaaa aaaagctctg gaaagtggct gagatttctg
    12421 atgataaaaa cagtgttata tttaaccgta taagtccgga tggcgagaat ggtttcccgg
    12481 gagaatttga tgtgtctgta aaatatgagt ttacggaaga caacgaactg aagatccatt
    12541 atcagggaat ctgcgatgag ccgacagttg ccaatatgac aaatcattct tatttcaatc
    12601 tgaatggtga gggaagcgga actgccatgg atcagtatct tacaatccat gcaaaatatt
    12661 atacacctgt agccaacagt cattccattc ctacaggagt gtatgaggaa gttgcaggga
    12721 ctcccatgga tttcagaact gccaaacaga tcgggcagga tattgaggca gaatttgacc
    12781 agctgaaatt cacaggcgga tatgaccaca attatgtgac agacaactat gcaaaaggaa
    12841 acagaagact gatcgcaacc gcatacagtg ataaaaccgg aattgccatg aatgtcactt
    12901 ccgactgtcc atgtgtacag ttttacgcag caaattttgt cgaaaatgaa catggtaaaa
    12961 atggtcatac ttacaataag cgggatgctt tctgtctgga aacgcaggtt gaaccgaatg
    13021 cggtcaatgt tgaagatttc cactccccga ttcttaatgc aggtgaacag tatgattctg
    13081 tgactgctta tcatttctac atcagaaagt aaaaatctga ccataaaact aattacatat
    13141 tgatccggtt tttttcatat ctacagcgtt ccagcatgaa aagaaccgga ttttattatc
    13201 cataattcat gtttgtcata acagcagttt catggtatga tagtaaacag agatattcga
    13261 aacagttatc tttataatta cagcaatcac cataaatgca ttatcagaaa tgactgctgt
    13321 aaaataacag aatggagaca tatatgaaaa agaaaaataa aacccggtct gttacagggc
    13381 ttttattcgg gtttatggaa cgtgtatccg gagatcacgt aggagcttat gcgacacagg
    13441 cagcgtattt tctgatcatg tcttttattc cctgcattct gtttctgact acactggtac
    13501 ggtatacacc tctgacctat aatgtagtca gggatgcgat cgttgctttt attccggaga
    13561 atctgcagag ttttgttctg gggatcgtgg tagatgtata caaaagaagt actgcaattg
    13621 tccctttgtc agcaattgtg gcactgtggt ctgccggaaa aggaatgcag tctatcatca
    13681 atggattaaa taccatttat cacgtaaaag aaacccgtaa ctggctgtta accagaattt
    13741 atgcagtatt ctatacttta tcactggtga ttgcggtaat cgtgtctctg cttatgcttg
    13801 tactcggaaa cgaaatacag aaagttgtat caagatatat tccttttctt ggaagagttc
    13861 tgggaaaaat actgggggca agagcactgt tggtatttgg tgtgttgttt ctggtttttc
    13921 ttatgttgta taaggttctt ccgaacagaa aagccacatt caaaagccag attcccggag
    13981 ccttgatcat agcagttgca tggtcgatat tttcatacgg attctctttt tattttgaga
    14041 tttttccggg attcagtaat atgtacggaa accttgcgac gatcatcatg gtcatggtat
    14101 ggttgtatat ctgtatgaat cttctgttat acggtgcaga gatcaatgct tattttgaaa
    14161 aagaattccg gattgcacat aaatcggtac aggaactgct ggcacatgaa aaagaaaaaa
    14221 agcagcagga aaatgaatga attctggctg ttactgttca ctggtaatat cccgcgaggt
    14281 gttttttgtg agcgaaggtc acagaaaacc cgagacatac tgcgcgaatt tatgcgatta
    14341 gcataaattc tgtgcatcgc gaagcgtgtt gctgggaacg gagtgaacag taacttttgg
    14401 ctacgttgtg aacatgacag tcagggggct ttttattgta aagcctttct gagtgtgcta
    14461 taataaacca taattttgga gaaacaaaaa ggaatcagtt ctatgatcgt tgtatatttg
    14521 atatttttgg ctgtcattca ggctgtgacg gaatttcttc ctgtcagcag cctgggacat
    14581 ttatgcatat tggaacaata tatgggaatc ggccacgaaa ccggattgct gtcagaaacg
    14641 atgctccatc ttggaagtgc ggcagcaatt atatttttgt tccgcaaaga tttaaaaaaa
    14701 atcggactgg gacttctggg gatgtttatg gatatgatcg gtaatctgaa tctatatatc
    14761 cataacaaga agacagggga aagtttgggc tatgccagaa tagtcaccgg aacatatcgg
    14821 aaaacaggtg cacttcttgt gatttccatg attccaacag cacttctggg acttacagga
    14881 aaacggctgg ctcttctggc cgcagactct cagattgttc cgggaatcgg atttttactt
    14941 acaggcgtat ttcttctggt aacagatctg aataaatccg gtggaaaaaa gggaccgaga
    15001 gaggcttctt atgacagcgc catgtggatt ggaatttgtc aggggattgc tgtctttccg
    15061 gggatttcca gaatgggatt tacgttatgt gctgcactgt tatgcggata taaccgcaaa
    15121 tttgcggttc gtttttctgt ttttatgagt ctgcctgcta tcataggtgc tttttttacg
    15181 gaaatcggaa attttggtgc ttctgaaatg acagcaggac ttgggtttac atatgtattt
    15241 gcaatgatca tcgccggttt tgcgggatgt cttgttatcc gaaatacaat agccatgact
    15301 cagaatataa aattacgcta ttttgcatat tattcattta tagtcggtat tattacactg
    15361 gcattaaatt ttgccctgta aagggaagat atttacgaga agatcaagga ggggagcctt
    15421 agaatggcag catcaaagag taagaatacc gggcattcgg gaagaaatac aaaaaagaag
    15481 acagcaatgg aacaggaagt cggcagattt cagacagaaa tcatattatt tgtgattttg
    15541 gccgcatgtg taatcctgat ggcaagcaat tttggagcag gtggttttgt gggagatgcg
    15601 atcagtaatt tctgtttcgg actgatggga ctgatggcat atctgtttcc aatcgtattt
    15661 ttccttgaat cagcatttat tctgatcaat aaaacaaacc ggctggcata taagaaactt
    15721 gcagcggcgt ttgtgatgtt tctgtttctg tgtggggcag cgcagcttct cacagatgga
    15781 tatatgcaga gtacaacttt gctggattat tatgctttaa gcgcagatta taaaacaggc
    15841 ggtggtctga tcggaggagc gatctgtatt tctgtcacat ctgcttttgg aactatcggc
    15901 ggatatgtga tcatta
//
