LOCUS       gnlProkkaICBEKFLC_148  14331 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ICBEKFLC_148.
ACCESSION   gnlProkkaICBEKFLC_148
VERSION     gnlProkkaICBEKFLC_148
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 05:13:46
            Original ID  :: gnl|Prokka|ICBEKFLC_148
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14331
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14331
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[7057:7742]"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      7058..7742
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR04223 or AgrB)"
                     /neighbourhood="10000"
                     /product="cyclic-lactone-autoinducer"
                     /protocluster_number="1"
     cand_cluster    1..14331
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR04223 or AgrB)"
                     /kind="single"
                     /product="cyclic-lactone-autoinducer"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14331
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="cyclic-lactone-autoinducer"
                     /region_number="1"
                     /rules="(TIGR04223 or AgrB)"
                     /tool="antismash"
     CDS             106..903
                     /locus_tag="ctg148_1"
                     /transl_table=11
                     /translation="MILAVISALCLAELLIVEKELKNRILLVLFGCCVLAVVLLIFYLY
                     DVLISAYKKLEEQSLMEKQMLIYSHQLDVLMQSEEKVKALRHDMKNHLGELALMAGNQN
                     NEEIRKYIHDMGEYMQNQSELVSCGNKNLDSLLNYLLGQAKKKLNHVEYEVRVPSDLCI
                     SAFDLNVILGNLTENAIEAAEQTKDKWMSVDIYYEKGILSMEIKNSFQHELAVEKNKLL
                     STKEEKGHGIGLANVRKMVEKYQGFMDVSNTNQIFTVKVMLYL"
     CDS             1317..1700
                     /locus_tag="ctg148_2"
                     /transl_table=11
                     /translation="MLSKKLKKVILGFVTALCLTGSAMPVMADTVRFNVTVPGDPKSKR
                     IPKSDDEQKFYVTGTYFSSYGTLSCRSYQLENQHVFSETKDISRTAPSNKGKYKSWAKP
                     HVYYFMSSHSSLNGMNVEGRYTP"
     CDS             1728..2825
                     /locus_tag="ctg148_3"
                     /transl_table=11
                     /translation="MEILPFSLRERKTMKIKAMAVIKITISCLIFFNSINTCFAADFPS
                     TYEKSSEKVKFDCELEIPKDFSETEMYSEKTKGRIYPDMDKTISIYTQGKEVKENGTIP
                     AASSEDPEGVYYVFTDGSTLSVDSSFTYGSDTAKYYGYIGVRDPQYKERFEQQTVSFMD
                     KNTVIEKVSSDLENIGIDTTDISWDAYPLNHEAMSQLENEQISDGLDMEEHRKESWTEE
                     DDAYFVYGVQMSQKLPVFHELMNTSRQLAYDTPDSSVIQAIYSKRGVEILSYSGYMYKF
                     DVSDQKINFLAFDDIASVVFDKFNNLLNESTYKITRAKLYERVFLNEAQQMEVSPVWYF
                     EILQDDDTTSITLVDAVSGEEIYLE"
     CDS             2844..3614
                     /locus_tag="ctg148_4"
                     /transl_table=11
                     /translation="MNYKSKGLLIKSDLSRLLKCYKIYAAIIGVSIAILFSTEQIGLIN
                     GNILDTYIQGSELSGIMIAYVFCAFPFATVFCEDLDNKYIRYELIRSNLKRYVVTKIAF
                     IYLTAILVMVLGTILFLLSGRIAGGDWVNESVGCMNVLLNGSYSILLKKEHYFLYCVMY
                     SLQLGLLSGLLSVLAGYFSLYIHNRVTVLALPIIIYQILIECSGNTIYTVFIFRAYNRP
                     MNKDWESFSLILLISIIPTILLGCLIYKKIQKRL"
     CDS             3618..4481
                     /locus_tag="ctg148_5"
                     /transl_table=11
                     /translation="MFKIMKYILKNTLLKIRNIKTITFAIIIAVTIWSYNHPLRELTYS
                     IKYPVTWCVFPFMISNLSFLILFWFGIIYINSDIPYMQHSNMYQIIRTGRISWALGQLG
                     GTFFRSFILVVFTAFCSIVSLLPQIEWSLQWGKLIHTIAMTNAAIQYNLKYVFYYQILG
                     KYSPLQLMIITIVICTFISMFLSSLMFMISLYFNHILAVSITAALTIMLFFVVNIHPKI
                     RYILAKFIPTVWAKVVQVNSPVLGYYWVPSIKYMFAFLLIGNIILIILILIKVKKCEFN
                     WENEDI"
     CDS             4496..5152
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 174.6; E-value:
                     4.2e-53)"
                     /gene_kind="transport"
                     /locus_tag="ctg148_6"
                     /transl_table=11
                     /translation="MNEKKYIIEVSHVNKSFKNNKVLKDVTLRCESGRIYGLVGHNGSG
                     KTVLFKTICGFLACDEGTVSVNGKVMGKDKDMLTEAGIIIEDPGFLRNWSAYHNLEFLY
                     TIRNRPDKSYLHSVLNTVGLDPKLKRPVGKFSLGMRQRLALAQAIMEDPPILILDEPMN
                     GLDKNGVAEIRELLLKMKNENKLIILASHNREDIEILCDEVYEMEDGILRKIVKE"
     CDS             5390..6112
                     /locus_tag="ctg148_7"
                     /transl_table=11
                     /translation="MLYIGICDDDEGVCAELERMLYDYAEQNKIQMDIDIWHRGESLCR
                     FLREKEQISDVLFLDIELLTTNGIEVGRFIREEQENMETAIVYISANSSYAMDLFRVQP
                     TDFLIKPLDKIKVGNVMDRIQKISEVRKGIFEYFVSGYYFKVLYKDILYFSSQNKKVHL
                     VLKDGQKEFNGKLKEIAKKIPGNFIQIHQSYLINFDYIEECSYESVKMKNGDTIPISQP
                     YRKSVRKQLAERVWRDRE"
     CDS             6205..6537
                     /locus_tag="ctg148_8"
                     /transl_table=11
                     /translation="MLIYSHQLDVLMQSEEKVKALRHDLENHLGELAFMAGNQNNEEIQ
                     KYIQDMGEYMQNQSELVSCGNKNLDSLLNYLLGQAKKKLNHVEYEVQVPSDLCISAFDL
                     NVILGN"
     CDS             6583..6810
                     /locus_tag="ctg148_9"
                     /transl_table=11
                     /translation="MSVDIYYEKGMLSMEIKNSFQHELDVEKNKLLSTKEEKGHGIGLA
                     NVRKMVEKYQGFMDVSNTNQIFTVKVMLYL"
     CDS             6825..7031
                     /locus_tag="ctg148_10"
                     /transl_table=11
                     /translation="MKDSVVVGLRCLLFCRKLVKRENIVTENLIKNHNMFSKNEFRQFI
                     YEFRHFRKFCNKYDIIQIQSKKK"
     CDS             7058..7192
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: TIGR04223"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg148_11"
                     /sec_met_domain="TIGR04223 (E-value: 4.1e-18, bitscore:
                     55.4, seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKELKKVIEKIAIKAASSNVNETCSWITYQPKVPESVKKLKKH"
     CDS             7194..7742
                     /gene_functions="biosynthetic (rule-based-clusters)
                     cyclic-lactone-autoinducer: AgrB"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg148_12"
                     /sec_met_domain="AgrB (E-value: 1.6e-38, bitscore: 122.1,
                     seeds: 181, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIQTFSEEEKEEIIRYGLDKIKNSCMMSAVTLLMGYAFHVFLQS
                     IVFLICFIALRKYAGGYHADTQKRCYVISVLIIAVALWATRYKSDNSVCFVFIQSLNFI
                     ILCFLVPVDSKNRRLEQWEKERYGKKAKVQIFCMYMLCLILYLDKKQSIAVAIGVANLT
                     VGGCVCAGKMKNILLKHKE"
     CDS             8142..9167
                     /locus_tag="ctg148_13"
                     /transl_table=11
                     /translation="MEKYIIMKKVNKFKLLAAGLLIGVAFWLLGSDFFTFMIWWEILWI
                     LGLVFMPITAQIFKGFDDNGWMNSKVIAIVICGYGVWILTSIKVVHFTTLSSVVITTLC
                     GGSSIAYGIYGKQRKVFPWKHMELVYWEEVIFFVVFLLWTYMAGFHPAAHGTEKYMDFG
                     FMKSMMHSTTLPSEDMWYAGKAFNYYYGGQYFAVFLTKLTGTKVEITYNLMRTMIAAFA
                     FVLPFSLVRQMLKDKLGKRGRAWITDFGGILAGLSVSMSGNLHYIIYGKIFTLLGIRED
                     YWFPSTTRFIGFDPPVTGDETIHEFPSYSFVLGDLHAHVINVFFVLAVGDFICMDKKKF
                     R"
     CDS             9316..10389
                     /locus_tag="ctg148_14"
                     /transl_table=11
                     /translation="MKPSDMRTGIKWSVVQWIELLLTAVLISLPFHLQFKSVMVQGIGI
                     VKIHTAFYQFCVLWAFPLLICGLFVVSTLIKNRNFTNKKTRNLFYKINVSDLYGVVLSL
                     CAMGLILIPEIVYVSDIYEKTAPRANTMFKLTYQAYILFALMMSYILVFFVADRIKILQ
                     ETKLDNRYEKKVRLSKVQITVGGMAIILLISTCGYFINATTNWFTGFPLKNKYQTLNAT
                     AYLENAIPEDAAAIRWLNKNITGQPTVLEACGDSYKDYDNRVSAMTGLPTVLGWYVHEW
                     LWRNNLDEENKRRTDVETIYTSTDKKEVQELLDKYEVNYIFIGSCEYQKYEGVNVALLS
                     SLGEIVFKEENTMIVKL"
     CDS             complement(11066..12643)
                     /locus_tag="ctg148_15"
                     /transl_table=11
                     /translation="MKKINNIIYSNPKQAVLPMLIQDYLDICDPVLTFDRFMGEIELEK
                     YLKNIPQHYTGRFRYAPVSMLKTVLFGFMANGYISLRELEDQCKVNLRFMYLMDHQTPS
                     YRTFGYFINEVLADSIEEIFRDINKKIFETEHVDLQHLYIDGSKFEANANKYSWVWKKA
                     TEKSRYRLFDKITELFKEINEELSCTGIKLCINSEYAPEYLKEAAEQYAEAWQIDETIF
                     VHGRGHRKTTQQRHYEKLREYTTKLEEYVEKIKICGEERNSYSKTDYSATFMRIKKDYM
                     GNDQLLPAYNVQVGVADEYIAVVDVNQYRSDMDCFIPLMNKFYTTYGFYPKYPVADAGY
                     GSYNNYIFCEQHGMKKYMKFPMFKKETTDKKYHEDPFRAVNFPIGKDGIMRCPNGKRFY
                     LQYQKNVKGNKYGRQEEVYQCEDCSSCPYAEQCKKTDKNRTVRINRELTAMHQEVIENL
                     ESIQGALLRMNRSIQAEGTFDIMKNDRWYKRIVRRGIKSVLLEVFLVSIGHNLYKYHNK
                     QKKGATAA"
     CDS             complement(12741..13319)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039:aldo/keto reductase family oxidoreductase (Score:
                     161.7; E-value: 3.8e-49)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg148_16"
                     /transl_table=11
                     /translation="MDPETPLEETMGALDSIVRSGKALYVGLSNYDGPTLKKATEILTY
                     LKCPFVINQNRYSIFDRTIENNGLKDTAYELGKGIIAFSPLAQELLTKRYLNGIPADSR
                     IATDGRFLNETALTSEKLSQIQALNEIAMERGQTLAEMALSWILKDDKVTSVLIGASKP
                     EQILDNIKIIGHTDFSDEELKKIDDIVNS"
     CDS             complement(13425..13748)
                     /locus_tag="ctg148_17"
                     /transl_table=11
                     /translation="MEVYTHVHCRQKRYDAIVYNRCGKSGLKLPVVSLGLWHNFGDTSV
                     YENMKQMCFTAFDNGITHFDLANNYGPAYGSAERNFGKLFREELHPYRDEMLISTKAGF
                     DMW"
     CDS             complement(13987..14106)
                     /locus_tag="ctg148_18"
                     /transl_table=11
                     /translation="MKHKALKKIEGGKSTQRVNIQKQKIKVQKLHLELLEKLQ"
ORIGIN
        1 tatacagctt aagcaacaag atggataatt ccttactggc tgtaagggat attaaccata
       61 aatatattgt agtagaataa aggagaagat aaaactccgc atgggatgat actggcggtt
      121 atttcagcac tttgtctggc agaattgctt attgttgaaa aggaactaaa aaatcgtatc
      181 ctgctggtgt tatttggatg ttgtgttttg gcagttgtat tattgatttt ctatttatat
      241 gatgttctga taagcgcgta taagaaactg gaagaacaat ctcttatgga aaaacaaatg
      301 ctcatttatt ctcaccagtt ggatgtgttg atgcaatcgg aagagaaagt aaaagctcta
      361 cgccatgata tgaaaaatca tctgggagaa cttgcactta tggctggaaa tcagaataat
      421 gaagaaattc ggaaatatat acatgacatg ggggagtata tgcagaatca gtctgaactg
      481 gtcagttgtg ggaataagaa tcttgacagt ctgctgaatt atcttctggg acaggcaaaa
      541 aagaaactga atcatgtaga gtatgaggta cgggtaccat ctgatttgtg tatatcagca
      601 tttgatctga atgtgatttt gggaaacctg acagagaacg caatagaagc agcagaacag
      661 acgaaagata aatggatgtc agtggatata tactatgaaa agggcatcct ttccatggaa
      721 ataaaaaaca gctttcaaca tgaattggct gtagagaaaa ataaattatt gtcaacgaag
      781 gaagaaaaag gacatggcat tggtcttgca aatgtcagga agatggtaga gaaatatcag
      841 ggatttatgg atgtttcgaa tacaaatcag atttttactg taaaggtaat gctgtactta
      901 taaattatgt agaatctatg aaagatagtg tagtggtagg actgcgctgt cttttatttt
      961 gcagaaaatt agtcaagagg gaaaatattg tgacagaaaa ccttataaaa aaccacaata
     1021 tattctgaaa aaacgaattt cgccaattta tatatgaatt tcgccgtttc agaaaatttt
     1081 gcaataaata tgctattatt taaatacaaa ctataaatga gcaagttcgt gattttgcat
     1141 aaaaaaaaag acaccttaaa tccagtgttg attttgaagc gtttatgaaa ttagcaggat
     1201 agttttgtac attttttcaa atttgctcat ttatagctat aataacactt gtcgttggtt
     1261 tactgcaaat tacgcgcgtg gttaaaatga caaaaaataa acaggaggtc aaatgtatgc
     1321 taagcaagaa attaaaaaag gttattttgg gatttgtaac tgcattatgc ctgactgggt
     1381 ctgcaatgcc cgtaatggct gatactgtcc ggtttaatgt gacagttccg ggagatccta
     1441 aatcaaagag aataccaaag tcagatgatg aacaaaaatt ttatgtgact ggtacatatt
     1501 tcagcagtta tggaacattg tcgtgtcgat catatcagtt ggagaatcag catgtctttt
     1561 ccgagacgaa ggatattagc cgtactgcac caagcaataa gggaaaatat aaaagctggg
     1621 caaaacctca tgtatattat ttcatgtcat cacattcgag tttgaatggc atgaatgttg
     1681 aaggaagata cacaccgtaa tattcatatt aaaaagaaaa aggcaggatg gaaatcttgc
     1741 ctttttcgct aagggagaga aaaacaatga agattaaagc gatggcagtt ataaaaatca
     1801 caattagttg tttgatattt ttcaatagta ttaacacttg ctttgcagcg gattttcctt
     1861 ctacctatga aaaaagcagt gaaaaagtga agtttgattg tgagttagaa attccaaagg
     1921 atttttcaga aactgagatg tactcagaaa aaacaaaagg ccgaatttat ccggatatgg
     1981 acaaaacgat ttcaatctac acgcagggaa aagaagtaaa agaaaatggg acaataccgg
     2041 cagcgtcttc agaagatcct gaaggagttt attatgtctt tacagatggc tctacattat
     2101 ccgttgacag ctcttttaca tatggttcag ataccgcaaa gtattatgga tatattggag
     2161 tacgtgatcc tcaatataaa gaacggtttg aacaacagac agtttctttt atggataaga
     2221 atacagtaat tgaaaaagta tcttcagatt tggaaaacat tggcattgat acgactgata
     2281 tatcctggga tgcttatcct ttaaatcatg aagctatgag tcaattggaa aatgaacaga
     2341 tttctgatgg gctggatatg gaagaacacc gaaaggagtc atggacagaa gaagatgatg
     2401 catattttgt ctatggcgta caaatgagcc aaaaattgcc agtatttcat gaattgatga
     2461 acactagcag acagttggct tatgatacac cagacagttc tgttattcaa gcgatttatt
     2521 caaagagagg cgtagaaatt ctttcttact caggatatat gtataaattt gatgtatcag
     2581 accaaaaaat aaattttctc gcatttgacg atattgcttc agtcgttttt gataagttta
     2641 ataacctgtt aaatgaatca acctacaaaa taaccagagc aaaattgtat gagagagttt
     2701 ttctgaatga agcgcagcag atggaagtta gccctgtttg gtattttgag attcttcagg
     2761 atgatgatac gacatccatt accttagtag atgctgtttc gggggaagaa atatatctcg
     2821 aataggaaag gctggagaaa aagttgaact acaaaagcaa aggtttactc ataaaatctg
     2881 atttaagcag acttttaaaa tgctataaga tatatgcggc aattatcgga gtaagtattg
     2941 caatattatt ttctacagaa cagataggat tgatcaatgg aaatattttg gatacatata
     3001 ttcagggatc agagctttcg ggaatcatga ttgcatatgt gttttgtgca tttccatttg
     3061 ctactgtatt ttgtgaagat cttgataata aatatatacg atatgaattg atcaggagta
     3121 atttaaaaag atatgtagtt accaaaattg ctttcatcta tttaactgca attttggtta
     3181 tggttttagg aacgatactt tttttattat cgggacgtat agctggtgga gattgggtaa
     3241 atgagtctgt gggatgtatg aatgttttgc tgaatggaag ttattccata ttactgaaaa
     3301 aagagcatta ttttttatat tgcgtaatgt actctttgca gcttggattg ttatccggat
     3361 tactatctgt attagctggt tatttttctt tatatattca taatcgtgtc actgtattag
     3421 cattaccgat tataatatat caaattctga tagaatgctc tggaaatact atttatactg
     3481 tatttatttt cagagcctat aatagaccaa tgaataaaga ctgggaaagc tttagtttga
     3541 ttcttttaat aagtattatc ccaacaattc tattaggctg tttgatatac aagaagattc
     3601 aaaagaggtt ataaaatatg tttaagatta tgaaatatat tttgaaaaat actttactga
     3661 aaataagaaa tataaagact atcacatttg caattattat cgccgtaacg atatggagtt
     3721 acaatcatcc tctgcgagaa ttgacttact cgatcaaata tccggtaaca tggtgcgtat
     3781 ttccttttat gatttcaaat ttgtcttttt tgatactttt ttggttcgga ataatctata
     3841 taaattcaga tattccatat atgcagcaca gtaatatgta ccagattatc agaacaggac
     3901 gtataagttg ggctctggga caattaggtg gaacgttttt tcggtccttt attcttgtag
     3961 tttttacagc attttgctca attgtttcat tacttccaca gatagaatgg agccttcaat
     4021 gggggaagct tatccatacg attgctatga caaatgcagc aatacagtat aatctgaagt
     4081 atgtgtttta ttatcagatt ttaggaaaat attcaccatt acaattaatg atcattacaa
     4141 tagtcatatg cacatttatt tccatgtttt taagttcctt aatgtttatg ataagcttat
     4201 atttcaacca cattttggca gtctcaatta cagcagcatt aacgataatg ctattttttg
     4261 tggtaaatat ccatcctaaa atacgatata ttcttgcgaa atttatccct actgtatggg
     4321 caaaggtagt gcaggttaac tctcctgtgc ttggatacta ttgggtacca tctataaagt
     4381 atatgtttgc atttttgtta ataggaaaca ttattttaat aattttgatt cttataaaag
     4441 taaagaagtg tgagttcaac tgggaaaacg aggatatata ggaggaataa ctgctgtgaa
     4501 tgaaaaaaag tatatcatag aggtatcaca tgtcaataag agttttaaga acaataaagt
     4561 cttaaaggat gtcacgctca gatgtgaaag tggccggata tatgggctgg tcggacataa
     4621 tggctctggg aaaacggttt tgtttaaaac aatttgtggc tttctggcct gtgatgaagg
     4681 aacggtttct gtaaatggaa aagtaatggg gaaagataag gacatgctta cagaggcagg
     4741 gatcattatc gaagatcctg ggttcttacg aaactggagt gcttaccata accttgaatt
     4801 tctgtacacg atacgaaata gaccagataa atcatatctg cattcagtgt taaacacagt
     4861 tggacttgat ccgaaattga aacgcccggt tggaaaattc tcgcttggta tgcggcagag
     4921 gctggcactt gcccaggcta ttatggaaga tccaccaatc ctgatcttgg atgagccaat
     4981 gaatggtctt gataaaaatg gtgtagcaga aatccgggag cttttgctga agatgaagaa
     5041 tgaaaataag ctgattatac tggcaagtca taatcgggag gatatagaga ttctatgtga
     5101 tgaagtatat gagatggaag atggaatact tcgaaaaata gtcaaagagt aagaaaaaat
     5161 atttcgtata gtttatattt cattttatct atagcacaac aagttaaatt atattgacag
     5221 aaaaattctc accactctga cgcgggattt cacactctga tgggctggat taagatgcat
     5281 tatttacgag gattgctata gtttccagag ctttgggagt gtgattattt ttatattgaa
     5341 aaagaatgcc aatggttata tacttctggt agtatgaaag gagtagaaaa tgttatatat
     5401 tggcatttgt gatgacgatg agggcgtttg tgctgaattg gaaagaatgc tttatgatta
     5461 tgcggaacaa aataaaattc agatggatat tgatatttgg cacagaggag agagtctgtg
     5521 cagatttctg agagagaaag agcagatttc ggatgtgttg tttctggata tagaattact
     5581 gacaacaaat ggaattgaag tgggacggtt tataagagaa gagcaggaaa acatggaaac
     5641 tgcaattgtt tacatttcag cgaacagcag ttatgcgatg gatttatttc gtgtacagcc
     5701 gacagatttt ctgatcaaac ctttagacaa aataaaagtt gggaatgtca tggacaggat
     5761 tcagaaaatt tcagaagtca gaaaaggtat tttcgagtac tttgtcagtg gatattattt
     5821 caaggtgctg tataaagata ttctgtattt cagcagtcag aataaaaaag tgcatctggt
     5881 tttaaaagac ggacagaaag aatttaatgg caaactgaaa gaaatagcaa agaaaattcc
     5941 gggaaatttc attcagattc atcagtcgta cctgatcaat tttgattata tcgaagaatg
     6001 ttcttatgaa tctgtgaaaa tgaaaaacgg agatacaatt ccgatcagcc agccatatcg
     6061 gaaatcagtg agaaagcaac tggcggaacg tgtgtggagg gacagagagt aaatgtttgc
     6121 gttgataact agattttcta tttatatgat gttctgataa gtgcgtataa gaaactggaa
     6181 gaacaatctc ttatggaaaa acaaatgctc atttattctc accagttgga tgtgttgatg
     6241 caatcggaag agaaagtaaa agctctacgc catgacctgg aaaatcatct gggagaactt
     6301 gcatttatgg ctggaaatca gaataatgaa gaaattcaga aatatataca ggacatgggg
     6361 gagtatatgc agaaccagtc tgaactggtc agttgtggga acaagaatct tgacagtctg
     6421 ctaaattatc ttctgggaca ggcaaaaaag aaactgaatc atgtagagta tgaggtgcag
     6481 gtaccatctg atttgtgcat atcagcattt gatctgaatg tgattttggg aaactgaata
     6541 gagaacgcaa tagaagcagc aaaacagacg aaagataaat ggatgtcagt ggatatatac
     6601 tatgaaaagg gtatgctttc catggaaatt aaaaacagtt ttcaacatga attggatgta
     6661 gagaaaaata aattattgtc aacgaaggaa gaaaaaggac atggcattgg tcttgcaaat
     6721 gtcaggaaga tggtagagaa atatcaggga tttatggatg tttcgaatac aaatcagatt
     6781 tttactgtaa aggtaatgct gtacttataa attatgtaga atctatgaaa gatagtgtag
     6841 tggtaggact gcgctgtctt ttattttgca gaaaattagt caagagggaa aatattgtga
     6901 cagaaaacct tataaaaaac cacaatatgt tttcgaaaaa cgaatttcgc caatttatat
     6961 atgaatttcg ccattttaga aaattttgca ataaatatga tattattcaa atacaaagta
     7021 agaagaaatg aaatatatgt gaaaggagaa taagaaaatg agaaaagaat taaaaaaagt
     7081 cattgaaaaa attgcgatta aagctgcttc ttcgaatgta aatgaaacat gttcatggat
     7141 tacatatcaa cccaaagtac cagaatcggt aaaaaaatta aaaaaacatt gatatggaaa
     7201 tacagacctt ttcagaagaa gaaaaagaag aaatcattcg atatggactt gataaaataa
     7261 aaaattcctg catgatgagt gctgttacac tgctgatggg atatgccttt catgtgtttt
     7321 tacaaagtat agtttttctt atatgtttta ttgctttaag aaaatacgca gggggttatc
     7381 atgctgatac acaaaagcgg tgttatgtaa tttctgtatt gattattgcg gttgcattat
     7441 gggcaaccag atataagtct gataatagtg tgtgttttgt ttttatacaa agtttaaatt
     7501 ttataattct gtgttttctt gttcctgtgg atagtaagaa tcgacgtctg gaacagtggg
     7561 aaaaagaaag atatggaaaa aaagcaaaag tacaaatatt ttgtatgtat atgttgtgtt
     7621 tgattttgta tttggataag aaacaaagta tagctgttgc tattggcgtg gcaaacctga
     7681 cagttggagg atgcgtatgt gcaggaaaaa tgaaaaatat tttactgaaa cataaagaat
     7741 aatttagaaa gggggaagta aactggataa aaaaacgaga tattatcaat gtagtagatg
     7801 cactgctata aaaaaagctt gaaagaattg acactgtttg tgtgtatata tgtttccggg
     7861 tcatgagatt tcaagagatg aagatatcaa aattttgaaa aatactgtga ggatttatgt
     7921 aattgatata aattttatat cttaaaaagc agtttgagaa tatcatggac ggttatatac
     7981 aattaaaaga tgatatagta cacaaaaaag tctggtaaaa acagactttt ttgtgtacta
     8041 taaaataagc agttttattg atgcaaaaaa agacatagag atattgtagc ttatatgatg
     8101 aagtgactgg tatatttttt gcttaattat ataaaaaaat catggagaaa tatattatta
     8161 tgaaaaaagt aaataaattt aagttgctgg cagcagggct attgatagga gttgcttttt
     8221 ggctgttagg atccgatttc tttacattca tgatatggtg ggaaatttta tggattcttg
     8281 gattggtatt tatgccgata acggctcaga tattcaaagg ttttgatgat aatggatgga
     8341 tgaattcaaa ggttatagca atagtgatat gcggatatgg agtatggatt ttgacttcta
     8401 taaaagtggt tcactttacc acattgagtt ctgtcgtaat tactacctta tgtgggggga
     8461 gcagtattgc ttatggaata tatggaaaac aaagaaaggt ttttccgtgg aaacatatgg
     8521 aacttgttta ttgggaagaa gtgattttct ttgttgtatt tcttttgtgg acatatatgg
     8581 caggatttca tccggcagct catggaactg aaaaatatat ggattttggt tttatgaagt
     8641 ctatgatgca tagcacaaca cttccgtcag aagatatgtg gtatgctggc aaagctttta
     8701 actactatta tggtggtcaa tattttgcgg tgtttcttac gaaacttaca ggaacaaagg
     8761 tagagattac atacaatctt atgcgtacca tgatagctgc atttgcgttt gtattgccat
     8821 ttagtcttgt gcgccagatg cttaaggata aattaggtaa aaggggaaga gcatggataa
     8881 cagattttgg aggtatttta gcaggtttat ctgtatccat gagtggaaac cttcattata
     8941 ttatatatgg aaaaattttt acattactgg ggataagaga agattactgg tttccaagca
     9001 caacacgatt tataggattt gatccacctg tgacagggga cgagacaatt catgaatttc
     9061 cttcatattc ttttgttctt ggggatttac atgcgcatgt gattaatgtg ttttttgttt
     9121 tggcagttgg ggattttata tgcatggata aaaagaaatt ccggtaaaag ctggaaacag
     9181 aaagagatat ttctgctggg actgttcctt ggaattttcc tgttttcaaa tacatgggat
     9241 tttatgattt attatgttgt aatatgtgga acactgtttt ttggaaattt gaagagatat
     9301 cttaattcta cagatatgaa accttcagat atgagaaccg gtataaaatg gagcgttgtg
     9361 caatggatag aacttctgct gactgctgtg ttgatttcgt taccattcca tttacagttt
     9421 aaaagtgtta tggtacaggg aatcggaata gtgaaaattc atacggcgtt ttatcagttt
     9481 tgtgtattat gggcttttcc attgcttata tgtggattat ttgtcgtatc tacgctgata
     9541 aaaaatagaa attttacaaa taaaaaaacc aggaatttat tttacaaaat taatgtttct
     9601 gatttatacg gagttgtact ttctctttgt gcaatgggac taatattgat tccggaaatc
     9661 gtttatgtaa gcgatatcta tgaaaaaaca gcaccaagag caaatactat gtttaagctg
     9721 acttatcagg catatatact ttttgcactt atgatgtcgt atattttggt attttttgtg
     9781 gcagacagaa taaaaatttt gcaagaaact aaattggata atagatatga gaaaaaggta
     9841 agattatcaa aagtgcagat aaccgttggg ggaatggcaa taatacttct tatatctacc
     9901 tgtggatatt tcataaatgc tacaacaaat tggtttacag gttttcctct gaaaaataaa
     9961 taccaaactc tcaatgcaac tgcttatcta gaaaatgcca ttcctgaaga tgcggcagca
    10021 atacgatggc tgaataaaaa tataacaggt cagccaactg ttcttgaagc ttgcggcgac
    10081 agttataaag actatgacaa ccgggtttct gctatgacag gattgccgac ggtattagga
    10141 tggtatgttc atgaatggtt atggcgaaat aatcttgatg aagaaaacaa aagaagaaca
    10201 gacgtggaaa ctatttatac ttcaacagat aaaaaagaag tacaggaact gcttgataaa
    10261 tatgaggtga attatatttt tattggaagc tgtgaatatc aaaaatatga aggggttaat
    10321 gtagcacttt taagttcatt gggagaaata gtttttaaag aggaaaatac aatgattgtg
    10381 aagctgtaat aaaacagatt tcaaaaagaa aacagtcaca tatttgagtg aatatcttaa
    10441 ttcatcagat gtaagtgact gtttcttttt attgctattt ttgaggtaac tgttttgggc
    10501 agatgattac agcatactta tactgtcgct attataacgg ctatatttag cttcctcata
    10561 tctgatcatg cagataaaag cgggttcaat atcttttact gtttgtgcaa cattacagaa
    10621 atattggaga ggaattgtgg caaaaaacct tataaaaaac acactatgtt ttgaaaaaac
    10681 gaatttcgcc aatttatata tgaatttcgc tgtttcataa aattttgcga cgaatgtgtt
    10741 atcatttaaa tataagtaag aagaactgaa atgtatctga agaaaggaga agtatcaaat
    10801 gaaacatagc agaagcaaaa acgcagtgtt attgatgatt atctttattt gtagtatttg
    10861 ttcgaataat gtgtgggctc gtgaaacagg gacaatggat caactggaaa aggagaatct
    10921 ggatgatgta gataaaatga ataaagggcg tgtgaaaaaa cgagagtttt ttcatgcgtc
    10981 cttttgctta tggatgtaat agtagttata ttacataaaa aagggtatag ttccccttac
    11041 cccataagaa tgctattatg aaatcctatg cggcagttgc accttttttc tgtttgttgt
    11101 gatatttata aagattgtgt ccgatagaaa caagaaatac ttcgagcagt acagatttta
    11161 ttcctcttcg gacaattctt ttgtaccagc gatcgttttt catgatatca aaagtacctt
    11221 ctgcctggat ggatctattc atcctcagaa gtgctccctg gatactttcg agattttcta
    11281 tcacttcctg atgcatcgct gtaagttcgc ggttgatccg aacagtacgg tttttatctg
    11341 tctttttaca ttgttctgcg tatggacagc tggagcaatc ttcacactga tacacttctt
    11401 cctgacgccc atacttgttt ccctttacgt ttttttgata ctgaaggtaa aatcttttcc
    11461 cgtttgggca acgcataatc ccgtctttcc cgattggaaa atttactgca cgaaatggat
    11521 cttcatgata cttcttgtca gtagtctctt tcttgaacat agggaacttc atatattttt
    11581 tcattccatg ctgctcacag aagatgtaat tattgtaaga accatatccg gcatctgcca
    11641 ctgggtattt cggataaaag ccatatgtcg tataaaactt gttcatcaat ggaataaaac
    11701 aatccatatc tgagcgatac tgatttacat cgacaacagc aatgtactca tctgcaacac
    11761 cgacctgtac attataggct ggaagcaact ggtcatttcc catgtagtct ttcttgattc
    11821 gcataaaagt ggccgaatag tctgtttttg agtagctgtt gcgctcttct ccgcagatct
    11881 ttattttttc tacatattct tccaacttgg ttgtatactc cctgagtttt tcataatgac
    11941 gctgctgcgt agttttacga tgtcctctac catgaacaaa tatcgtttca tcaatctgcc
    12001 aggcttcagc atactgctcg gcagcttctt ttaaatactc tggtgcatac tcactattga
    12061 tacaaagctt tatccctgta catgacagct cttcattgat ttccttaaag agttcagtaa
    12121 tcttatcaaa gagccggtat ctggattttt ctgtggcttt tttccacacc caggaatatt
    12181 tatttgcatt tgcttcaaac ttggaaccat cgatgtatag atgttggaga tccacatgtt
    12241 ctgtctcgaa gatttttttg tttatgtctc gaaatatttc ttcaatggaa tcagcaagca
    12301 cctcattaat gaagtagccg aaggtacgat aagaaggggt ttgatggtcc ataagataca
    12361 taaagcggag attgacttta cactgatcct ccagctcacg taacgatata tagccattcg
    12421 ccataaatcc aaacaaaact gtcttcagca tactgaccgg ggcatatcta aatcttcctg
    12481 tataatgttg cggaatattt ttcagatatt tctccagttc gatttctccc ataaatctgt
    12541 caaaagtcag cactggatca cagatgtcca gataatcttg aattagcatt ggcaaaactg
    12601 cctgttttgg gttagaataa attatgttat taattttttt cacaagttaa ttataacaga
    12661 aagaaagacc ttgagttcat tataaactct tggtctttct tttttcagga ctattctttt
    12721 ttcacagccc ctttcattga ttaagaatta acgatatcat caatcttctt aagttcttca
    12781 tctgaaaaat cagtatgtcc gattatcttg atattatcaa gaatctgctc aggttttgaa
    12841 gctccaatca ggacacttgt tactttatca tcttttagaa tccagctaag agccatctcg
    12901 gcaagcgtct gtcctctttc catagcaatt tcgttaagtg cctgaatctg ggaaagcttt
    12961 tctgatgtaa gtgcagtctc attaagaaat cgtccgtcag tggcaattct gctatcagca
    13021 gggataccat tgaggtagcg cttcgtaaga agttcctgtg cgagaggaga gaaagctatg
    13081 ataccttttc caagctcata ggcagtgtcc ttaagcccgt tattctcaat tgttctgtca
    13141 aaaatagaat aacggttttg gttgattacg aaaggacatt tcaaataggt taggatttct
    13201 gtagcctttt taagtgtggg accatcataa tttgaaagac ctacataaag ggcttttcca
    13261 cttcgaacga tagagtcaag agcacccata gtctcctcaa gtggtgtctc aggatccatt
    13321 ctgtgatgat agaagatatc gacataatca agtccaagtc gcttaagact ctggtccagg
    13381 cttgcaataa ggtacttgcg gcttccccaa ttgccataag gtccttacca catatcaaat
    13441 ccggcctttg tgctgatgag catttcatct cggtatggat gaagttcttc cctgaaaagc
    13501 ttgccgaaat tgcgttctgc actgccataa gcaggcccat aattattggc aaggtcaaaa
    13561 tgagtgattc cattgtcaaa agcggtaaag cacatctgct tcatattttc gtagacactt
    13621 gtatcaccaa aattgtgcca gagtccaagt gaaacaacag gcagcttcaa gccactttta
    13681 ccgcagcggt tgtaaactat tgcgtcgtat cttttttgtc tgcaatgtac atgtgtatat
    13741 acctccatga ttatatcttt ctgctacact taggatatca tattttttct tcaattgcat
    13801 ccagctcttc atttcatcct ctgttttcgc tgtatacgtt actgttcaca cgatgtgcga
    13861 ccagcaacgc atctcgccat tttaaatcgc ctttggcgat ggggcgagat gcattcaagc
    13921 caaaacatgc atcctccgtg tcaatcagcg aagtgattga cacgggagtg aacagtaacc
    13981 tgtatgctac tgcaatttct ccaacaattc cagatgaagt ttctgcacct taatcttttg
    14041 tttttgtata ttcactcttt gagtggactt tcctccttcg attttcttta aagctttatg
    14101 cttcataaac tcttctttta tatagttttt tcaaaacaac tatagtaata tagagttatc
    14161 acaatcttag cttcctacta ttcaacggtt ccttttcgcc atatccagtg gggtgggtaa
    14221 agatgaccca ataagtgaat gtaattgaag aaatgtaagc gcaccatagt gcatatatag
    14281 acattattat agtaatttga gataattacc tcaacaatta atacttgtca a
//
