LOCUS       c00018_gnlPro..        15700 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KMOIHJCH_18.
ACCESSION   c00018_gnlPro..
VERSION     c00018_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 10:05:23
            Original ID  :: gnl|Prokka|KMOIHJCH_18
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15700
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15700
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2583:5700]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2584..5700
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15700
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15700
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             494..1009
                     /locus_tag="ctg18_1"
                     /transl_table=11
                     /translation="MLAWLPFFLISLMFIVLLYACTRSARTNIQRFKQLSLIAFLWVLT
                     AFCYTPTSYNFGTQLVIQYIQWGPVKLNVIPFQQLDIEFWLNVLLTVPLGGLLAWNFPD
                     LPWRRFIWLGFLTGLTLELGQFILDWLVNLKRWVDIDDVITNWAGVIIGAAGYKIARHV
                     PGLRWLQK"
     CDS             complement(1177..2166)
                     /locus_tag="ctg18_2"
                     /transl_table=11
                     /translation="MRMLEKIEQYIDSCIEAGDIYGASFSLITPKGINQYYHGKQGRDE
                     FAVGLDPAMIYDLASVTKVVGTTTRIFQLLSDHTIHLTDSVARFLPGFTHPEITIKNLL
                     LHNSGLPADIDNLDKMQREDLIKAVYDAPLVTAPGTTYVYSDLGFILLGWIIRAVDGSL
                     ARSIQDHVCYPLAMTNTGYNLNRPKIRFVPTEFDPRRGQIQGQVHDYKAFLLNGESGHA
                     GLFSTLTDLSVFIEMMLNFGEYQGKRVLDENVFDWLGEYDENGRTLGWERRAGRHQYFH
                     TGFTGPAVAFDLDRQIGLVVLTNRVYPTSDNQVWNQDRKRVFDLFFES"
     CDS             2584..4842
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_3"
                     /sec_met_domain="Gly_radical (E-value: 4.6e-39, bitscore:
                     126.9, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 7.5e-246, bitscore:
                     810.7, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITSEKTTKPAAWKGFKGGHWQEEINIRDFIQNNFTQYNGDESFL
                     AGPTAATKTLNDKVLELKKQERAAGGVLDADTKVVATITSHGPGYIQKDLEKIVGLQTD
                     KPLKRAFMPFGGIRMADDALKSYGYTPDEENDKIFTEYRKTHNQGVFDVYTPDMRKARH
                     YKIITGLPDAYARGRLIPDLPRVAVYGIDRLMEDKANDFAHIGDGELTDDVIRLREEVQ
                     DQYRALADMKKMAASYGYDISKPATNAQEAIQWMYFAYLAAIKTQNGAAMSVGRIDTTM
                     DIFIQRDLDNGVLDESQAQELIDQFVMKLRMVRFIRTEEYNSLFSGDPIWATLSMCGLG
                     VDGQHHVTKTAFRILKTLDNMGAAPEPNITILWSDRLPEDFKRYATEVSIDSSTIQYEN
                     DDLMRVQWGTDYYGIACCVSAQPIADGIQYFGARANLAKAILYAINGGRDEIAGDQVGP
                     AYEPITSEYIDYDEFMKKLDKQMDWLADTYVNSLNAIHYMHDKYYYEAAQLALKNTDLD
                     RTFATGISGLSHAADSISAIKYGHVKVIRDERGIAVDFKADNDYPRYGNNDDRADDIAK
                     WLVKELYSKMNTHHLYRNAKLSTSVLTITSNVVYGKNTGTTPNGRQKGEPFSPGANPAY
                     GAEKSGALASLLSTAKLPYRYATDGISNTFGVTPNTLGHDLESRKDTLVNMLDGYMKND
                     GMHLNINVFNKDTLIDAQKHPEEYPTLTVRVSGYCVYFADLTKEQQDDVISRTFFESM"
     CDS             4879..5700
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 74; E-value:
                     4.8e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg18_4"
                     /sec_met_domain="Radical_SAM (E-value: 7.3e-27, bitscore:
                     88.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKQVSTTQAAAKEPLIGYVHSIETFGSVDGPGIRYVAFLQGCH
                     MRCQYCHNPDTWKLNVGDQMTADEILEDAAKYRAFWGKTGGITVSGGESLVQIDFILDL
                     FEKAKAMNISTCLDTSGQPFTREQPFFDKFERLMKVTDISLVDIKHIDSAKHKQLTQYG
                     NENILDMIQYMAQHHDDMWIRHVLVPQRTDYDEDLKKLGDYIAKIPNDVVQKVEVLPYH
                     TLGVKKYHEMKIKYRLEGIESPTQDRVANAEKLLHTADYNGYKTWMPLPKL"
     CDS             complement(5925..6236)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FeS_assembly_P"
                     /gene_functions="other (smcogs) SMCOG1048:Iron-sulfur
                     cluster assembly protein (Score: 67.1; E-value: 3.9e-21)"
                     /gene_kind="other"
                     /locus_tag="ctg18_5"
                     /sec_met_domain="FeS_assembly_P (E-value: 1.2e-20,
                     bitscore: 67.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTFKDRAFEALGHVIDPELGIDLVNLGLIYDAQLTAEGTAEIT
                     MTLTIAGCPLTEWLAKDIHDELIKLPEVNNIEIEIVWEPAWNESMMSREARMELGIHS"
     CDS             7297..8217
                     /locus_tag="ctg18_6"
                     /transl_table=11
                     /translation="LKTINLGHSNIQASSVALGIMRMDALDVAQATKVIDTAADLGINY
                     VDSADIYGGGQSSTIFGQALKQAHVSRDQLYIQSKGGIVPGKRYDFSKQHILAAVDGEL
                     QRLGVDYLDTFLLHRPDALMEPEEVAAAFDKLQTSGKVRHFGVSNFNPMQVDMLQAALN
                     QRLIINQLQFGIMHTGAIDFGLHTNMQDERSLNHDGEMIEYSRLHKMTIQAWSPYQYGN
                     FAGIFLDNPKFPELNNAMQALADEKQVTKSAIATAWILRHPAHFQVVLGTMNPEHLAQN
                     AAGADVTLSRQEWYDIYFAAGNDLP"
     CDS             8387..8911
                     /locus_tag="ctg18_7"
                     /transl_table=11
                     /translation="MTSTCTICERIKLIQAHQNPYFVYELTTGYVVLADSQYFEGYTLF
                     LAKHHVTELHHLPAHEKLRYLEEMSIVQEACAQAFHADKMNIELLGNGDAHVHWHLFPR
                     HNGDTLNPGPVWWTPLETIYGDDVSLDIPRLSRLKRTLSVAIEATLNAREAELQALEAL
                     TRPASHRIDSN"
     CDS             complement(9006..9251)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GlcNAc_2-epim"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_8"
                     /sec_met_domain="GlcNAc_2-epim (E-value: 0.0004, bitscore:
                     13.3, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTAPLSSFEKNIPAVTELLAVDAELQTFFVALTPGYQREWARFI
                     FGTKAQATKERHIEVMKTVFRAGYKSKRAYDSRPDK"
     CDS             9424..9852
                     /locus_tag="ctg18_9"
                     /transl_table=11
                     /translation="MPKFDITLISPERAKAMLTEYKEQRKNSVPHLAHPGRYILPDYKL
                     TRRRAAFKIVKHTFLTPHYKSYVAMDSDNGHTLWFHNFGSLTEALFWLETGLKISDTDS
                     HSNYKEWMAKHTTEIETFKDLLREQKHKQGPKTKKKAK"
     CDS             complement(9955..10596)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg18_10"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 8.8e-19, bitscore:
                     62.2, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAISNGHVSFKRPAWLGDSITANNGLTTVHYHDILAADWDVERSD
                     NLGISGSTIGSRYDAMAARYQAIPEDADFIAVFGGVNDYGRNQPLGQYGDCDMTTFYGA
                     LMVLLTGLQTNWPTVPKLFISAIHIGSDFGGSFSAVTNGLGYRQSDYEAAIAQMTADYG
                     VPHLSLYRDAGMTFAIPTQAAIYSVATLHPNNAGHRVIARKLQSFLDSHF"
     CDS             complement(11612..13279)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BCCT"
                     /gene_functions="transport (smcogs)
                     SMCOG1001:betaine/carnitine/choline family transporter
                     (Score: 410.4; E-value: 2.8e-125)"
                     /gene_kind="transport"
                     /locus_tag="ctg18_11"
                     /sec_met_domain="BCCT (E-value: 8.7e-125, bitscore: 410.4,
                     seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSSRFIILKSKNIDWWVYLPTIGLFAAASVVLLMGGHSLETSLS
                     GILNWLTNNMSWLYMSVYVITFIFFIYLGFSKLGKTKLGDPDDKPEFSTYHWGSMVYAT
                     GIDASILMLSMVDPLRYLQSPSFGVKPFSTSAYNYAHMLGQFNWGPMAWMMFAPATIAI
                     AYAMYVKHIKVQRLSAAISVLQGPGKGKQIARNTIDFLVIIGIMGGVGTSVGMEIPVIS
                     KVLSAVTGIADTMTLKLGLFALLFVIFAMAVFNGLKKGIGRLSAAHVWLAIGFLIVVLI
                     VGPTLYILNSETNSIGLFVNKFITLSTNTAPNGHATAMQRQTIFYWGWWLSFMPVMGLF
                     IARISRGRTIRQVLGGMLLWGSLGCVSFYAILGGYALYLQRMGIVNLVHILNTQGQAAV
                     IAAVLSTLPLKMIMLALYCLSCFIFLATTVSSFAFITSSFTSKKLAAGEQPSRFNRMSW
                     VVIFLVFSLGLVTVGGFESIQSICAMSGFPLTIVALVLLYSIHHDLTTDPVKEAAKANA
                     KAAELARRKRLARDVEITTKTDYARERRTARKRETEAD"
ORIGIN
        1 ccaggatcaa actctcaaat taatgatgag ttctaaaaag ctcatttaat gttgtactaa
       61 aatttatttg ctagcgaatt gacttcgcaa atgttttgct cttgattcaa aatcaagaga
      121 ccctacacat ttgattcgtc gaaactttgt tcagttttca aagatctaat tccgtgcgtt
      181 aatcgcttaa cacaacttaa tcatcataac atcttaatca atatcttgtc aacaactttt
      241 tttaagaagt aacttgatta atttgtcata gttgccgttg cgacaacaga aactatctta
      301 ccaattactg aagaaattgt caacaactaa tttcaataat tatttggtgg tgagatgcat
      361 ctgccgtagc agcaacgttt actaatatac caattgaagt aaaaagtgtc aacacttttt
      421 ctgaatttct ttttattaat agtcaaacca gctttttttc tctatactat ttaattaaag
      481 gagcgactaa attatgctag cttggctacc attctttttg atttcattaa tgtttattgt
      541 tctactatac gcttgtacgc gatcagcgcg cacaaatatc cagcgtttta agcaactcag
      601 tttaattgcc tttctctggg tcttaactgc tttttgctat acacctacca gttacaattt
      661 tggtacccaa ctcgttattc aatatattca atggggaccc gttaagctga acgtgattcc
      721 tttccaacaa cttgacattg aattttggct caacgttctc ctcactgttc cattgggcgg
      781 tttactggca tggaattttc ccgacttgcc ttggcgtcgt tttatttggt tgggatttct
      841 tacggggcta acactcgagc tgggacaatt catccttgac tggttggtta acctcaaacg
      901 ttgggttgat atcgatgatg tcatcacaaa ttgggctggt gtcattatcg gtgccgctgg
      961 ttataaaatt gcacgtcatg ttcccggact tcgctggttg caaaaataac gtatatatag
     1021 aagcaaaaag caaaatagcg tttgcttagc acccacaagt gccaaacact tcagcggtct
     1081 agctgtcatg aaatcgtaat taaataagcg tcgcagcctt aagtggctgc gacgcttatt
     1141 taatttaact actaactatt aatgaagctg ccatcatcag gattcaaaaa acagatcgaa
     1201 tactcgctta cgatcttggt tccagacctg attgtcacta gttggataaa ctcgatttgt
     1261 taacacaacc agcccaattt gacgatccaa atcaaaagca actgccgggc cagtaaaacc
     1321 agtatggaaa tattgatgtc gtcccgcacg tcgttcccaa cctaacgtcc ggccattttc
     1381 gtcatactcg cctaaccagt caaagacatt ttcatccagc acccgtttgc cttgatattc
     1441 accaaagttt aacatcattt caataaatac ggataaatcc gtcagcgttg agaacaagcc
     1501 tgcgtgacca ctctcaccat tcaacaaaaa ggctttataa tcatgcacct gtccttgaat
     1561 ctgaccccgc cgcggatcaa actccgtcgg cacaaaccga atcttcggac gatttaagtt
     1621 ataacccgta ttggtcatcg ctagtggata gcaaacgtgg tcttgaatac tccgagccaa
     1681 tgagccgtca accgcacgaa taatccatcc caataaaata aatcccaggt ctgaatagac
     1741 atacgttgtc cctggtgccg tgacgagtgg cgcatcataa accgctttga tcagatcttc
     1801 acgttgcatc ttatccaggt tatcaatatc tgccggtagc ccactattat gaagtaacaa
     1861 gtttttaatc gttatttcag gatgagtgaa cccaggtaaa aaccgggcaa ccgagtccgt
     1921 taaatgaatc gtgtggtccg ataacaactg aaaaatcctc gtcgtggtcc ctacaacctt
     1981 agttaccgat gctaggtcat aaatcatcgc aggatctaag cccacggcaa actcatcgcg
     2041 gccctgctta ccatgatagt attgattgat acctttaggg gtgatcaagc taaacgacgc
     2101 cccataaatg tcgccagctt caatacaact gtcaatatat tgttcaattt tttcgagcat
     2161 ccgcattacg cccacctttc actacattca ctagtttctg cttatcttct ttatgataac
     2221 gaacttcctc ataaaatcaa cggcaaacgc ttttaacacc ctccacacct cgttgcactt
     2281 tttattaatt aactagttaa acacttgtta cattatggac aatattccac ttatatatca
     2341 aaacgagtct tgtttttagc cgttttctaa atataattaa gtgaattacc aatgcctatc
     2401 tagctatgta agtactgtta tatcaacgtt aatagtcaac ttttcaataa tagattgcaa
     2461 aaaaataacc caaacgtgaa ataaatcacc tgaaagcggt tacaaatcca gcaaaaaatg
     2521 ttatgattca aatatagaat tttatcaatc atttgattgg attcaaatta tggaggcgag
     2581 aaaatgatta catcagaaaa gacaacaaaa ccagcagctt ggaaaggttt caaaggcggg
     2641 cactggcagg aagaaatcaa cattcgtgat tttattcaaa ataacttcac acagtacaat
     2701 ggcgacgaaa gcttcctggc cggaccaaca gccgctacta agaccttgaa tgacaaagtc
     2761 ttagaattaa agaaacaaga acgtgccgct ggtggtgtgt tggatgctga tactaaagtc
     2821 gttgcaacga ttacttcaca cggccctggt tatattcaaa aagatctcga aaagattgtt
     2881 ggtctccaga ctgacaagcc tttgaagcgg gccttcatgc catttggtgg tattcgaatg
     2941 gctgatgacg ctttgaaatc atacggttat acccctgatg aagaaaacga caagattttc
     3001 actgaatatc gcaagactca taaccaaggc gtcttcgatg tttatactcc tgacatgcgg
     3061 aaagcacgtc actacaagat catcaccgga ctaccagatg catacgcacg tggccgtctc
     3121 attcctgatc ttccacgggt cgctgtttat gggatcgatc gtttaatgga agacaaagct
     3181 aatgactttg cccacattgg tgatggtgaa ttgactgatg atgttattcg cctccgtgaa
     3241 gaagttcaag atcaataccg tgctttagca gatatgaaga agatggctgc cagttatggc
     3301 tacgatatta gcaagcctgc aactaatgct caagaagcta ttcaatggat gtacttcgct
     3361 tacttagctg ctatcaagac ccaaaacggc gctgcaatgt ccgttggccg gattgataca
     3421 acgatggaca tcttcatcca acgtgacttg gacaatggtg ttctggacga aagccaagct
     3481 caagaattaa ttgatcaatt cgtcatgaaa ctacggatgg ttcggttcat ccgtactgaa
     3541 gaatacaatt ctctcttctc tggtgaccca atctgggcaa ccttatcaat gtgtggttta
     3601 ggcgtcgacg gtcaacacca tgtgactaag actgctttcc ggattttaaa gactttggac
     3661 aacatgggcg ccgcaccaga accaaacatc acgattttat ggtcagaccg cttaccagaa
     3721 gacttcaaac gttacgcaac tgaagtttca atcgacagtt caaccattca gtatgaaaat
     3781 gatgacttga tgcgggtaca atggggtacc gattattatg gcattgcttg ctgtgtttcc
     3841 gcacaaccaa ttgctgatgg aatccagtac ttcggtgccc gggcaaactt agccaaagcg
     3901 attctttatg ccatcaatgg tggccgcgac gaaattgctg gagatcaagt tggccctgct
     3961 tacgaaccaa ttacttcaga atacatcgat tacgacgaat tcatgaagaa attagacaag
     4021 caaatggatt ggttagctga cacttacgtt aactcactga atgcaattca ttatatgcat
     4081 gataagtact actatgaagc tgcccaatta gctttgaaga atactgatct tgatcggacc
     4141 tttgcaactg ggatttctgg cttatcacat gccgcggatt caatctcagc tatcaagtat
     4201 ggtcacgtta aagtaattcg tgacgaacgt ggtatcgccg ttgacttcaa agccgacaat
     4261 gactacccac gttatgggaa caatgacgat cgcgctgatg acattgctaa atggttagtc
     4321 aaagaattat acagcaagat gaacacgcat cacctctatc ggaatgccaa actttcaact
     4381 tctgttttga cgattacctc caacgttgtt tatggtaaga acactggtac cacaccaaat
     4441 ggccgtcaaa aaggcgaacc attctcacca ggtgctaacc ctgcatacgg tgctgaaaag
     4501 agtggtgcat tagcttcact tctttcaact gccaaattac cataccgtta cgcaactgac
     4561 gggatttcca acacgttcgg cgttacccct aacacgttag gccatgacct cgaatcacgg
     4621 aaagacacgt tagtaaacat gttagacggt tacatgaaga acgatgggat gcacttgaac
     4681 atcaacgtct tcaataaaga cactttgatt gatgctcaga aacaccctga agaataccca
     4741 acattaacgg ttcgggtttc tggctactgt gtctacttcg cagatttaac caaggaacaa
     4801 caagatgacg ttatttcacg gacattcttc gaatcaatgt aacatttaat ctttaatagt
     4861 taagaaggcg aaaggctcat ggaaaacaaa caagtttcaa caacgcaagc ggcggcaaag
     4921 gagcctttga taggctacgt tcactccatc gaaacgtttg gctccgttga cggaccaggt
     4981 atccgttacg tggcattcct tcaaggatgc cacatgcgtt gccaatactg tcacaaccct
     5041 gatacttgga aactcaacgt tggcgatcaa atgacggccg acgagattct cgaagacgcg
     5101 gctaaatacc gggctttctg gggcaagacg ggtggcatca cagtcagtgg tggtgaatca
     5161 ctggtacaaa tcgacttcat cttggactta ttcgaaaaag ccaaggcgat gaatatcagt
     5221 acttgtctgg atacctctgg acagcctttt acccgagaac aacctttctt tgacaagttc
     5281 gaacgtctaa tgaaggtcac ggacatttcg ttggtcgaca ttaagcacat cgattctgcc
     5341 aaacacaagc agttgaccca gtatgggaac gaaaatatct tggatatgat tcagtacatg
     5401 gcccaacacc acgatgatat gtggattcgt cacgtcctgg ttccccaacg gactgattac
     5461 gatgaagact tgaagaaact cggcgattac attgctaaaa ttccaaacga cgtcgttcaa
     5521 aaagtcgaag tattgccgta ccatactttg ggcgttaaaa aatatcatga aatgaagatc
     5581 aagtaccggc ttgaaggaat cgagtctcca acccaagatc gggtggcaaa tgccgaaaag
     5641 ctactgcaca ctgctgatta caacgggtac aagacatgga tgccattgcc aaaactttaa
     5701 atcggcattt ctagcatgac taaaacacca gcgatacaat cgtctacgga tggttgtgtc
     5761 actggtgttt ttttgctggc tcgacgcata cacgtattgc tggctggaat tagtacagcg
     5821 gcacgcaaaa aaggcgccgc gagcctaaac cagcaacgtc tttccttaat catgccctat
     5881 ccaatgaccg tcagcccttg gactggctgc gaacaggccg gccactaact atgaatgcct
     5941 agttccattc gagcttcgcg agacatcata ctttcgttcc aagcaggttc ccacacaatc
     6001 tcaatctcga tattgttaac ttctggtaat ttgatcagtt catcgtgaat gtccttagcc
     6061 aaccattcgg tcaaaggaca gcccgcaatg gtcaacgtca tggtaatttc agcggtcccc
     6121 tccgccgtca attgtgcatc atagatcaac cccaagttaa ctagatcaat tcctaattca
     6181 gggtcaatga catgtcctag cgcctcgaag gcccggtctt taaacgttgt tgtcatcgta
     6241 tctcgtcctt ccataccagc ttgaattcac tgattaatca cgccaacgtt tcgcggtata
     6301 agtgccacca cacttgatac acgtcatcgt tatataaagc gctttcttgt ctacttctat
     6361 tgtaccgtat gtcagcccat attcaatcaa ttattagcgc taattaaccg acttttcaaa
     6421 cggtcggtca atcagcaaat tatgcgacta tttctcgaaa aaaattcact ataatccccg
     6481 atatagcagc gttttgagtc actattgatt tttattgcga attcacggtt gtttttgttg
     6541 taagcgtttg cggtttatgc tattatacta agtgaggaaa ggaattaatc ctcgattagc
     6601 aaagcttctc aaaagagttt ggctgtcgct gtaatgttag acagctagta tcacagtttg
     6661 ggtcgttatc gaaaccgttt taagcgccgt gaagcgttat cggtctagcg agtgtcgtga
     6721 gatttacgtt ggatgactga acgttgaccc ttagataaac gataaccgca aagaattaat
     6781 tggcattaga atgacgaaca gattttaact aagttttagt tggaaacagg tgtctccgat
     6841 gaccagttgt tagttccaca ttaccagttc catttgtaga ctcaggtatt acaaagttta
     6901 aacggaggtg catgtctgtt acgaagacat tcccaagttt taaacgcgag tttgactttc
     6961 gttaaaaccc gtctaacgag tcgcaatcaa gtaacaacct tactttagat cgactatagc
     7021 agatagttac aataaatacg ggttagtccg ttagaagttg gacacgcgta aaattgaata
     7081 gcatgaaggt gtatcatatt aacactgaac aatttttcat tgctaatcag gattattcct
     7141 cataagtaga actcaagcag agaagccttg ggttctattt ttttgctcta aaatcagatt
     7201 taccaacagt cggcaccaga cgtaaccgtt tacatcctct tacgaaaacc gtatactgaa
     7261 tttaaatcaa gttgcacatt gaggaggact ttagttttga aaacgattaa tttaggtcac
     7321 agcaatattc aagcttccag cgtggcgctt ggcatcatgc gcatggacgc cttggatgtc
     7381 gctcaagcca ccaaggttat cgataccgct gctgatttag gcatcaatta cgttgattca
     7441 gctgatatct acggtggtgg tcaatcatcg accatcttcg gtcaagcact caagcaggct
     7501 cacgtatcgc gtgatcagct ctatattcag tcaaaaggcg gcattgttcc tggcaagcgt
     7561 tacgactttt ccaaacagca catactggca gccgtggatg gcgagcttca acgcttaggt
     7621 gttgattatc tcgacacctt cctcctccat cgaccggacg ccctgatgga acccgaagaa
     7681 gttgctgccg cttttgacaa gttgcaaact agcggcaagg tgcgccactt tggcgtctct
     7741 aacttcaatc ccatgcaagt tgacatgctt caagcggcac taaaccaacg gctcatcatc
     7801 aaccaactcc aatttggtat catgcatacc ggtgcgatcg actttggctt gcacacgaac
     7861 atgcaggacg aacgtagtct taaccacgac ggcgagatga tcgaatactc acggctccat
     7921 aagatgacga ttcaagcttg gtcgccttat caatacggta acttcgcggg tatcttctta
     7981 gacaatccga agtttccaga acttaataat gccatgcaag cactcgccga tgagaaacag
     8041 gtcactaaat cagctattgc gaccgcatgg attctccggc acccagccca cttccaagtc
     8101 gtccttggta cgatgaatcc ggaacatcta gctcaaaatg ctgctggagc agacgttacg
     8161 ctttctcggc aagaatggta cgacatttac tttgcagctg gcaacgattt accttaatca
     8221 cgatcgacct aacagaattg acgattagtt tttacaatca aaacgacgac cccaaatcag
     8281 gattgatttt caggtcgtcg ttttttagac gtttcactaa catttttgat gtactcacca
     8341 catctacgcg tatacttaat cttatcaaga ctcaggaggc gagcgaatga catccacttg
     8401 cacgatctgt gaacgaatca aactaattca ggcacatcag aatccttatt tcgtttacga
     8461 actcacaacg ggctacgtgg tccttgctga tagccagtac tttgaaggct acacgctctt
     8521 tttagccaaa catcacgtta ccgaattaca tcatttaccg gcacacgaga agttacgata
     8581 ccttgaagag atgagtatcg tccaggaagc ttgtgcgcag gcctttcatg cagacaaaat
     8641 gaacattgaa ctactcggga atggtgacgc gcatgttcat tggcacttat ttcctcgcca
     8701 taacggtgat acgctcaacc ccggtcccgt ctggtggaca ccgctggaaa caatttatgg
     8761 tgatgatgtc agtctagaca ttccccgttt aagccggttg aagcgcacgc tcagcgtagc
     8821 aattgaggcc acgcttaatg ctcgggaagc agaattgcag gctttagagg cactcacaag
     8881 gcctgctagc cacagaattg acagcaatta gaccaaatca ggacccagac ccgcttagat
     8941 cttggtggct acaccccaat tcttaatcgc aatccgtcac cgtatttcaa attgccaaaa
     9001 tccacctatt tatccggccg actatcatac gctcgcttag atttatagcc agctcgaaaa
     9061 accgtcttca taacttcaat gtgccgttcc ttagttgctt gtgccttagt tccaaaaata
     9121 aagcgggccc attcgcgctg ataaccaggt gtcaaagcca caaagaacgt ttgcaattca
     9181 gcatcaaccg ctaacaattc ggttaccgcc ggaatatttt tttcaaatga actgaggggt
     9241 gctgtactca taatcaaacc tccgattagt tttacttaaa tttactgtaa gaaagggaaa
     9301 atccctaatt ttcaggtttt tatatttcga attttcataa aattgcgcta tcattatagt
     9361 ataagtatta ttatttgact actataatta accatactgc tattcaccaa ggggagccct
     9421 gctatgccaa aatttgatat caccctcatc agtcccgaac gcgctaaagc gatgttgact
     9481 gaatataaag aacaacgtaa gaactctgtc ccacatctgg cccatcctgg ccgctatatc
     9541 ttgccggatt acaaattaac tcgtcgccgg gccgcattca aaattgttaa acataccttt
     9601 ttaacgcccc actacaagtc ttacgttgcc atggactctg acaacggcca cacactctgg
     9661 tttcataatt tcggttccct aaccgaagct ttattctggt tagaaaccgg ccttaaaatc
     9721 agcgataccg actcccattc taactacaag gaatggatgg ctaagcacac tacggaaatc
     9781 gaaaccttta aagacttgct gcgcgagcag aagcataaac aagggcccaa gactaagaaa
     9841 aaagccaagt agcccgtttt gacacctaga ttcagataag cagcagtacg ctcattagcg
     9901 tgctgctgct tttatttacg atcaactgtg ccattcatta ctgactaggc caacctaaaa
     9961 gtggctatcc aaaaacgact gcagcttgcg tgcaatcacg cgatgaccgg cattgttcgg
    10021 atgcaaagta gccaccgaat aaatggccgc ttgagtggga atcgcaaacg tcattcccgc
    10081 atcacggtac aagctcaaat gtgggacgcc atagtccgca gtcatctggg caatcgctgc
    10141 ttcataatct gactgacgat acccgagacc attagtcacc gcactaaaac tgccgccaaa
    10201 atcagagcca atatgaattg ctgaaataaa taacttcggc acggtcggcc aattcgtctg
    10261 taatcccgtc agtaacacca ttaacgcgcc ataaaatgtc gtcatatcgc aatcaccgta
    10321 ttgccctaac ggctgattcc gaccatagtc attgacgccc ccaaagacag caataaaatc
    10381 agcatcttca ggaatagctt gatagcgcgc cgccatcgca tcgtagcgac tcccaatcgt
    10441 tgaaccagag attcccaaat tatcgctccg ctcgacatcc caatcagccg ccaaaatatc
    10501 atgataatgc accgtcgtca acccattatt cgccgtaatc gaatctccca accacgccgg
    10561 ccgcttaaaa ctaacgtgcc cattactaat cgccatagcc aatcctccct ttactatcat
    10621 cgctaccatt ctaatccatc ccatctgaat tatggtagaa agatgccttt atttaaagtc
    10681 aacagccacc agcttaggcc cgctggaaac agttccggtt agcgtaaacc tgcttagttc
    10741 gttcgtccta cgccgccctc caggaatttc tgccaattgc tggaacgcgg tggacacaga
    10801 tttaagccga agaccacgtc ttaaatactg gtcttccact aaccaagcca aggacgcttg
    10861 ctaagtggaa tttcaccgct gagcattggc cgaaacgcct tccagtcggg acagtattcg
    10921 aatggcggac gaagatgtac ccaacttttg atgaatttgt cattgttctc cataaacagt
    10981 aattttgtta atcaactgtt aggtcgaaaa gatattggga tagctcgcta tttcggaatt
    11041 actatagtaa taatagaaca cctcaacaaa gtggttaggg taaccctaac gtctcgttta
    11101 aagttcctgt atcaaaataa ccaacgacca attgtgccga gttaagtggc cgttcatcag
    11161 ccattcgagc ggcttcctga aacgtgttcg gtgccactaa agtctgtgct tgctatgcca
    11221 acggacaaat gcccaaaccg cattaatccg ttggctagac aatgctcggc ttcaacccgt
    11281 ggcttgagac tggaggggct gggtgacaat gctcagtagc caaattattc ttagtcggaa
    11341 gtgatttcct tccggcttag aataagactc gtatttgaga tgacgcgggt tatgcgttag
    11401 ctcaaatcga tgtcggctgc gttccagcaa ttgtcaccca gccccggagg tcggaatagg
    11461 acgctcaccg gctgacgaac agaaaaccaa ccctaaaagg catctttcta ccattatttc
    11521 aaacaggtgg gccaatctta aaaggctcgt attatggaaa tccataatac gagcctagtt
    11581 taattgatat atttagttca actgagtagc gctaatcggc ttccgtttca cgtttccgtg
    11641 cagtacgccg ttcgcgtgcg tagtcagttt tagttgtgat ttcaacgtca cgtgctagcc
    11701 gtttccggcg tgctaattca gctgctttgg cattggcttt cgcagcttcc ttgactggat
    11761 cagtcgttaa gtcgtgatgg atcgagtaca gtaagacgag cgcgacaatc gttaatggga
    11821 agccagacat cgcacagatg gactgaatcg attcaaagcc accgaccgtg acaagcccca
    11881 atgagaagac taggaagata acgacccagc tcatccgatt gaaacgactt ggttgttccc
    11941 ccgcggccaa ctttttacta gtaaatgacg aggtaatgaa ggcaaatgaa gataccgtcg
    12001 ttgctaagaa aataaagcaa gataggcagt acaaagccag cataatcatc ttcaatggta
    12061 aggtcgacaa tactgctgca atcacagcgg cttgtccttg cgtatttaag atatgaacta
    12121 agttaacgat gcccatccgt tgcaagtata aggcataacc acccaagatg gcgtagaaac
    12181 tgacacaacc taatgagccc catagcaaca taccaccgag tacctgacga atcgtccggc
    12241 cccgagaaat ccgggcaatg aataagccca tgactggcat aaaggataac caccagcccc
    12301 agtagaagat cgtctgccgt tgcatggccg ttgcgtgacc atttggtgca gtattcgtgc
    12361 tcaacgtaat aaacttattg acaaacaagc caatactatt agtttctgag tttaaaatat
    12421 acaaagttgg gccaacaatt aaaacaacga ttaggaagcc aatcgctaac caaacatggg
    12481 cagcacttag ccgaccgatt cccttcttca aaccattaaa aacagccatg gcgaaaatta
    12541 cgaataataa ggcaaataac cctaacttta aagtcatcgt atcggcaatc ccggtaacgg
    12601 cactcaaaac ttttgaaatg acggggattt ccatcccgac tgaagtacca acaccaccca
    12661 taatcccaat aataacgaga aaatcaatcg tgttccgggc aatttgctta cccttaccag
    12721 gaccttgtag tactgaaatt gcggcactga gccgctgaac cttgatgtgt ttaacataca
    12781 ttgcataggc aattgcaatc gtggctggcg caaacatcat ccacgccatt ggtccccaat
    12841 taaattgtcc cagcatgtgc gcataattat atgcagaagt tgaaaacggc ttgacgccga
    12901 atgaagggct ttggaggtac cgtaacgggt caaccatgct caacattaag atgctggcat
    12961 cgatcccggt cgcgtaaacc atactgcccc agtgatacgt tgaaaattct ggtttgtcat
    13021 caggatcacc aagtttggtt ttccctaact tactaaaccc taagtaaatg aaaaagataa
    13081 aagtgatcac atataccgac atataaagcc agctcatgtt atttgtgagc cagttcaaga
    13141 tgccacttaa actcgtctcc agcgaatggc cccccattaa taaaacaacg gaagccgccg
    13201 caaagagccc aattgttggt aaatagaccc accaatcaat attcttactt tttaaaataa
    13261 taaacctgct actgagcata tactctctat atttagatca aattcgtggt tcttcctacc
    13321 agcaatggta gtccccacgc gtaaatttcc gactagcaat cggtacaccc ctccgagtta
    13381 atcctcggag cactcagcac cctgactgta tcaggtttga ccggcattgt catccgcatt
    13441 ctgtttgtgc taactcaaaa tcagtagcag aatttccttc tttccgttgg ttgaatccgg
    13501 acaacgccat actgacaaat gatttttaat tgcttaatcg acgttggtgt tcatcttgtt
    13561 tagctagtgt ttctattacc atcgtgcctt tagcacacga ccgtcgtcac accacgtaac
    13621 gattaatggt tacactgctc ttgctaatag ataaccccct tgaatcacca gataagccca
    13681 ccgcacaact gttagattaa ttgcttggtg caccaaaaaa gcgcttagta ccgggtaaca
    13741 agttaccacc tgcacagcgc acgttggctt atacaaatgc tgatttcagt attttctgat
    13801 atctgatgtt cgtttataag tatactagta ttaaatcaga agtaaaatca accattttga
    13861 gccgtcgagg cctaacccgt caaggattag acgagttttg cacccatatt ttttctgaaa
    13921 ctttttaaaa gttttcgtaa taattagttt tttagtttag aatcattctt atctgtttca
    13981 attaaaccga tttcatgtta ttcttgtaac aagtaaaaaa acgttatcat ctaaaaggag
    14041 gggaactgca tgcggcacta ctataaatta attttaacgg tcagcgtcgg tatcattgcg
    14101 gttattttac agtttggttt gcactaccaa ttggcagcac aaatcatcat tacattaatg
    14161 gggtcactta tggccttatc aatgttagtt gagatgatca aaaccttacg ttcaggtaag
    14221 tacggggttg atttattagc aattacggcg attgtggcaa cactagctgt cggcgaatat
    14281 tgggctagcc ttgtcgttct aattatgctc actgggggtg actcgttaga agattatgcg
    14341 gccaaacgag cgaataccga attgaaagcc ttgctcgata attcaccacg tattgcccac
    14401 cgctcagtcg ccggccaatt aacagatatt gccgttgaag atgtccaaat tggtgatcag
    14461 ctagtcgtca aacctggtga gctagttcca gtagacggtc accttattca aggaacggca
    14521 ctctttgatg aatcttcatt gacgggtgaa tctaagccag tcgacaagca cgttggcgat
    14581 gacattatgt ctggtgcggt caacggcgat agtgctgtta caatggttgt tgataaatta
    14641 gccattgata gtcaatacca acagttagtc aaattggtta aagaatccga atcacgacca
    14701 gccaaattcg tacggctggc cgatcgctat gcagtcccat tcaccttggt agcatacgtc
    14761 attgccggag tagcttgggc attcagcggt gatccccacc gatttgcaga agtcctcgta
    14821 gtggcttcac cttgcccgct gattctcgcc gcacccgttg cactcgtctc agggatgagc
    14881 cgaactagtc ggaacggaat cgtggtcaag actggggaca tgttggagaa gttatctacg
    14941 gctaagtccg ccgcgtttga taagacgggg accattacca gtggtcaatt aacagtcaac
    15001 caaattgttc ctcagcctgg ttttactgcc gaacaaatct tgcacctcgc agcgagcgct
    15061 gaacaaaact caagtcatat cctggcccgc tcactcgtca agtatgcgag tgccactagc
    15121 ctcagcccgg caacacaatt agcagaagta acgggtaatg gggtcacggc aacgattgag
    15181 cagcaacagg tcaaagtggg caaacttaaa ttcgtcgcac cgactacaac cgccaagcca
    15241 cttgctacca ctgctatcta cgtcggcatt gatgaccagt acgcgggtta catcacgttt
    15301 atcgacaatg tccgccccga agcagccgcc acgcttcaag cactccacgc tgagggcgtt
    15361 caaaacgtca tgatgcttac tggtgaccaa caggcaattg ctgatcatat tgccgccgat
    15421 gtcggtatcg ataccgttgc tgccgacctc ctacccgcag ataaaattgc ccacttaaag
    15481 gctgtaccag cgggcgaacg ccccgttatc atggttggcg atggtgttaa cgacgcgcct
    15541 tccctggctg ttgctgacgt cggcatcgcc atgggcgccc atggctcaac tgctgctagt
    15601 gaatcggccg acgtcgtcat cttaaaagac gatcttagtc gcgtggtcac ggcggtgcgc
    15661 attgctaaag ataccatgca agtggctaaa caagccgttt
//
