LOCUS       gnlProkkaCGPGODHF_21   10111 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CGPGODHF_21.
ACCESSION   gnlProkkaCGPGODHF_21
VERSION     gnlProkkaCGPGODHF_21
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 09:45:15
            Original ID  :: gnl|Prokka|CGPGODHF_21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10111
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10111
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1:10109]"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2..10109
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     cand_cluster    1..10111
                     /SMILES="NC([*])C(=O)N1C(CCC1)C(=O)NC(CCC(=O)N)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX))"
                     /kind="single"
                     /product="NRPS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..10111
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS"
                     /region_number="1"
                     /rules="cds(Condensation and (AMP-binding or A-OX))"
                     /tool="antismash"
     CDS             complement(2..6391)
                     /NRPS_PKS="Domain: NRPS-COM_Nterm (0-30). E-value: 3.8e-19.
                     Score: 59.5. Matches aSDomain:
                     nrpspksdomains_ctg21_1_NRPS-COM_Nterm.1"
                     /NRPS_PKS="Domain: Condensation_DCL (7-303). E-value:
                     1.2e-113. Score: 371.0. Matches aSDomain:
                     nrpspksdomains_ctg21_1_Condensation_DCL.1"
                     /NRPS_PKS="Domain: AMP-binding (469-866). E-value:
                     8.4e-106. Score: 345.8. Matches aSDomain:
                     nrpspksdomains_ctg21_1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (972-1041). E-value: 6.3e-26. Score:
                     82.3. Matches aSDomain: nrpspksdomains_ctg21_1_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1055-1334). E-value:
                     5.5e-102. Score: 332.6. Matches aSDomain:
                     nrpspksdomains_ctg21_1_Condensation_LCL.1"
                     /NRPS_PKS="Domain: AMP-binding (1500-1901). E-value:
                     9.6e-109. Score: 355.5. Matches aSDomain:
                     nrpspksdomains_ctg21_1_AMP-binding.2"
                     /NRPS_PKS="Domain: PCP (2003-2071). E-value: 3.8e-25.
                     Score: 79.8. Matches aSDomain:
                     nrpspksdomains_ctg21_1_PCP.2"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1209:polyketide synthase associated protein papA3
                     (Score: 19.1; E-value: 5.9e-06)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_1"
                     /sec_met_domain="PP-binding (E-value: 2.6e-19, bitscore:
                     56.8, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 4.1e-91, bitscore:
                     292.2, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 8.4e-122, bitscore:
                     393.7, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKKNAIQDIYPLSYMQEGMLFHSLLQKESQAYAEQASFSITGKV
                     DTRVFEESVHALFERHDIFRTIFISQNVSVPQQVVLKERNVSIIEENLTNLNKADQIKY
                     IEEAKRRDREKGFHLQKDMLMRVTLLQTGECEYTCIWSFHHIIMDGWCLGIVLKEFFQI
                     YASRLRRTPLTLEPAVPYGTYIKWLMEQDKEKAASYWERYLEGFEQQTVLPKQKKAGKS
                     RQEEVTFSFSKEDTAKLKELAVKEEVTLSTIFHTLWGILLQAYNQTEDAVFGSVISGRP
                     SEIEGIERMIGLFINTVPVRISGADIPFQKLIKNVQKDALKGQAYSYHPLYDIQANSQV
                     KQGLIDHILVFENYPVEQELDVLNSKGDTKDLFHIHDFSMEDETNYSFYLMVAPGDEIH
                     LKMRFDSSVYDRQFIENIKGHLAHIVSQVLDKPDITPDKLEIITPGEKVQLLAPISEET
                     EKPEYDTVHAMFERQAAKTPDQIAIRYEGESVTYKELNESANKLARLLKKRGLKREEPV
                     GVMLGRSPSLAAAVLGILKAGGAFVPIDPGSPKERIRYVIENSGCVHVVTERHQSVPAE
                     QTLQVTYIEEAGTEADGSNVQSINTADDLLYMIYTSGTTGKPKGVLLEHKNMANLLSHQ
                     LTNTDIDFCTNVLQYASLAFDVCYQELFSVLLSGGTLCIVPESIKRDVSQLFSFIDQHN
                     TEVVFFPTAFVKMLFNEEGYAQSFPRCVKHVITAGEQLTVSRLFRQTLRLYGMHLHNHY
                     GPSETHVVSTYTISAGDDIPEQPPIGKPIHHNKMYILSKNRQLQPLGIAGELYISGANT
                     GRGYVNNPALTEEKFLPDPFRTDAVMYRTGDLARLRADGQIEYIGRTDDQVKIRGYRIE
                     PKEIETVLANHHAVKEAAVLIQTNESGENELCAYCSVSQATDPSQLRRDLAKELPDYMI
                     PVKWAFVDSIPLTANGKVDQRALPEASAYAAGRRYTAPRNVTELKLTRIWEEVLQTSPI
                     GVHDHFFELGGHSLKATALVAKIAKECSVQIPLSDVFSHPTVEELAKIISEAEENPFAS
                     IEKTETKETYPVSSAQKRMYVLHQLENGGVSYNIPAVLEVKGPFDRDRMEAVFKELIWR
                     HEPLRTSFEEKNGLPVQRIHDEVPFAFTKEQSAEAFIRPFDLGKAPLFRAGFVQIEKDR
                     HLLLADMHHIISDGVSVNLLIREFSELYAERSLPPLRIQYKDYAVWQQSFMAGAAYRKQ
                     EEYWLNRLAGEIPVLELPADKPRPPVRSFSGDRVSFVISEKHTAQLKKLAKENKCTLYM
                     TLLGVYTVLLARLSGQEDMIVGSPIAGRPHADLDAVLGMFVNMLAFRTRPDGSMTFKEY
                     LKEIRQTALEAYEHQDYPLEELVDKLGVPRDMSRNPLFDTTFALQNMEQQKLRASGLEL
                     QPADVSLPISKFDLSLYISENAGELYCQFEYSTDLFKRKTIQKWAEFFTTLAENAAADP
                     GLELDDISVLTEKEEASLLQDFSPLQKTAFPLHQPLHDLLEQQAEKTPDRPAILTDDIS
                     ITYQELNERANELAHRLIKRGIRLEDKTAIMGRRSPDMLIGIYAVLKAGGAYLPIDPDY
                     PKERIRFLLKDSGVKFLLAEPELLAADLFEGEMISLKSGQTGNPEAAANPNVPVKPDSL
                     AYIIYTSGSTGRPKGVQVEHQSAVNFLYSLQTRYGLSDSDIILHKTSYSFDASIWELFW
                     WPIAGASVFLLPQGGEKDPEMILNALENNRITAAHFVPSMLHAFLEYINSRKQPIKKTC
                     LKRVFAGGEQLGPHLASRFYDLLPGTELTNSYGPTEATVEAAYFDLPQGKEFHNVPIGI
                     SGHNMRLYILNQKKQLLPPGCIGELYIAGTGVARGYLNRPELTEERFLDDPFYPGERMY
                     QTGDIARWTEDGLVEWLGRSDGQVKVRGYRIEPGEIEAAIRRIDGIREAAVTARTEHGE
                     TALYAYIEGRESDDVRAELATRLPAYMMPAQFIKMTEWPVTPSGKLDRRALPAPGGAAD
                     RQAYTVPRNVTEMKLCALWEEVLKNGPVGIRDHFFERGGHSLKATALVSRIAKEFGVQV
                     PLQDIFARPTVEELASVIQDLEESPYEAIQPAQTQDIYPVSSAQKRMYVLQQLEDGGVG
                     YNMPAVLELTGPLDRGRLEE"
     aSDomain        complement(179..382)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_PCP.2"
                     /evalue="3.80E-25"
                     /label="ctg21_1_PCP.2"
                     /locus_tag="ctg21_1"
                     /protein_end="2071"
                     /protein_start="2003"
                     /score="79.8"
                     /tool="antismash"
                     /translation="EMKLCALWEEVLKNGPVGIRDHFFERGGHSLKATALVSRIAKEFG
                     VQVPLQDIFARPTVEELASVIQD"
     aSModule        complement(179..3226)
                     /complete
                     /domains="nrpspksdomains_ctg21_1_Condensation_LCL.1"
                     /domains="nrpspksdomains_ctg21_1_AMP-binding.2"
                     /domains="nrpspksdomains_ctg21_1_PCP.2"
                     /locus_tags="ctg21_1"
                     /monomer_pairings="Gln -> Gln"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(437..463)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0023"
                     /evalue="1.70E-01"
                     /label="NRPS-A_a10"
                     /locus_tag="ctg21_1"
                     /protein_end="1985"
                     /protein_start="1976"
                     /score="5.1"
                     /tool="antismash"
                     /translation="GKLDRRALP"
     CDS_motif       complement(659..724)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0022"
                     /evalue="3.30E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg21_1"
                     /protein_end="1911"
                     /protein_start="1889"
                     /score="35.2"
                     /tool="antismash"
                     /translation="WLGRSDGQVKVRGYRIEPGEIE"
     aSDomain        complement(689..1891)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_AMP-binding.2"
                     /evalue="9.60E-109"
                     /label="ctg21_1_AMP-binding.2"
                     /locus_tag="ctg21_1"
                     /protein_end="1901"
                     /protein_start="1500"
                     /score="355.5"
                     /specificity="substrate consensus: Gln"
                     /tool="antismash"
                     /translation="LEQQAEKTPDRPAILTDDISITYQELNERANELAHRLIKRGIRLE
                     DKTAIMGRRSPDMLIGIYAVLKAGGAYLPIDPDYPKERIRFLLKDSGVKFLLAEPELLA
                     ADLFEGEMISLKSGQTGNPEAAANPNVPVKPDSLAYIIYTSGSTGRPKGVQVEHQSAVN
                     FLYSLQTRYGLSDSDIILHKTSYSFDASIWELFWWPIAGASVFLLPQGGEKDPEMILNA
                     LENNRITAAHFVPSMLHAFLEYINSRKQPIKKTCLKRVFAGGEQLGPHLASRFYDLLPG
                     TELTNSYGPTEATVEAAYFDLPQGKEFHNVPIGISGHNMRLYILNQKKQLLPPGCIGEL
                     YIAGTGVARGYLNRPELTEERFLDDPFYPGERMYQTGDIARWTEDGLVEWLGRSDGQVK
                     VR"
     CDS_motif       complement(806..895)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0021"
                     /evalue="2.70E-18"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg21_1"
                     /protein_end="1862"
                     /protein_start="1832"
                     /score="58.0"
                     /tool="antismash"
                     /translation="PPGCIGELYIAGTGVARGYLNRPELTEERF"
     CDS_motif       complement(1004..1033)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0020"
                     /evalue="4.60E-02"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg21_1"
                     /protein_end="1796"
                     /protein_start="1786"
                     /score="6.9"
                     /tool="antismash"
                     /translation="SYGPTEATVE"
     CDS_motif       complement(1418..1477)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0019"
                     /evalue="1.70E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg21_1"
                     /protein_end="1658"
                     /protein_start="1638"
                     /score="32.7"
                     /tool="antismash"
                     /translation="AYIIYTSGSTGRPKGVQVEH"
     CDS_motif       complement(1514..1546)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0018"
                     /evalue="1.80E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg21_1"
                     /protein_end="1626"
                     /protein_start="1615"
                     /score="-0.7"
                     /tool="antismash"
                     /translation="KSGQTGNPEAA"
     CDS_motif       complement(1664..1702)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0017"
                     /evalue="5.90E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg21_1"
                     /protein_end="1576"
                     /protein_start="1563"
                     /score="16.3"
                     /tool="antismash"
                     /translation="AVLKAGGAYLPID"
     CDS_motif       complement(2231..2350)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0016"
                     /evalue="5.30E-21"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg21_1"
                     /protein_end="1387"
                     /protein_start="1347"
                     /score="67.1"
                     /tool="antismash"
                     /translation="RQTALEAYEHQDYPLEELVDKLGVPRDMSRNPLFDTTFAL"
     aSDomain        complement(2390..3226)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_Condensation_LCL.1"
                     /domain_subtypes="Condensation_LCL"
                     /evalue="5.50E-102"
                     /label="ctg21_1_Condensation_LCL.1"
                     /locus_tag="ctg21_1"
                     /protein_end="1334"
                     /protein_start="1055"
                     /score="332.6"
                     /tool="antismash"
                     /translation="ETYPVSSAQKRMYVLHQLENGGVSYNIPAVLEVKGPFDRDRMEAV
                     FKELIWRHEPLRTSFEEKNGLPVQRIHDEVPFAFTKEQSAEAFIRPFDLGKAPLFRAGF
                     VQIEKDRHLLLADMHHIISDGVSVNLLIREFSELYAERSLPPLRIQYKDYAVWQQSFMA
                     GAAYRKQEEYWLNRLAGEIPVLELPADKPRPPVRSFSGDRVSFVISEKHTAQLKKLAKE
                     NKCTLYMTLLGVYTVLLARLSGQEDMIVGSPIAGRPHADLDAVLGMFVNMLAFRTRP"
     CDS_motif       complement(2399..2488)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0015"
                     /evalue="1.20E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="ctg21_1"
                     /protein_end="1331"
                     /protein_start="1301"
                     /score="40.2"
                     /tool="antismash"
                     /translation="DMIVGSPIAGRPHADLDAVLGMFVNMLAFR"
     CDS_motif       complement(2747..2779)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0014"
                     /evalue="1.00E-04"
                     /label="C4_LCL_164-176"
                     /locus_tag="ctg21_1"
                     /protein_end="1215"
                     /protein_start="1204"
                     /score="14.9"
                     /tool="antismash"
                     /translation="QYKDYAVWQQS"
     CDS_motif       complement(2810..2875)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0013"
                     /evalue="8.40E-10"
                     /label="C3_LCL_132-143"
                     /locus_tag="ctg21_1"
                     /protein_end="1194"
                     /protein_start="1172"
                     /score="31.1"
                     /tool="antismash"
                     /translation="MHHIISDGVSVNLLIREFSELY"
     CDS_motif       complement(3047..3157)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0012"
                     /evalue="2.40E-13"
                     /label="C2_LCL_024-062"
                     /locus_tag="ctg21_1"
                     /protein_end="1115"
                     /protein_start="1078"
                     /score="42.5"
                     /tool="antismash"
                     /translation="SYNIPAVLEVKGPFDRDRMEAVFKELIWRHEPLRTSF"
     aSDomain        complement(3269..3475)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_PCP.1"
                     /evalue="6.30E-26"
                     /label="ctg21_1_PCP.1"
                     /locus_tag="ctg21_1"
                     /protein_end="1041"
                     /protein_start="972"
                     /score="82.3"
                     /tool="antismash"
                     /translation="ELKLTRIWEEVLQTSPIGVHDHFFELGGHSLKATALVAKIAKECS
                     VQIPLSDVFSHPTVEELAKIISEA"
     aSModule        complement(3269..6370)
                     /complete
                     /domains="nrpspksdomains_ctg21_1_Condensation_DCL.1"
                     /domains="nrpspksdomains_ctg21_1_AMP-binding.1"
                     /domains="nrpspksdomains_ctg21_1_PCP.1"
                     /locus_tags="ctg21_1"
                     /monomer_pairings="Pro -> Pro"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(3530..3556)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0011"
                     /evalue="1.70E+00"
                     /label="NRPS-A_a10"
                     /locus_tag="ctg21_1"
                     /protein_end="954"
                     /protein_start="945"
                     /score="2.4"
                     /tool="antismash"
                     /translation="GKVDQRALP"
     CDS_motif       complement(3764..3829)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0010"
                     /evalue="1.70E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg21_1"
                     /protein_end="876"
                     /protein_start="854"
                     /score="36.1"
                     /tool="antismash"
                     /translation="YIGRTDDQVKIRGYRIEPKEIE"
     aSDomain        complement(3794..4984)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_AMP-binding.1"
                     /evalue="8.40E-106"
                     /label="ctg21_1_AMP-binding.1"
                     /locus_tag="ctg21_1"
                     /protein_end="866"
                     /protein_start="469"
                     /score="345.8"
                     /specificity="substrate consensus: Pro"
                     /tool="antismash"
                     /translation="FERQAAKTPDQIAIRYEGESVTYKELNESANKLARLLKKRGLKRE
                     EPVGVMLGRSPSLAAAVLGILKAGGAFVPIDPGSPKERIRYVIENSGCVHVVTERHQSV
                     PAEQTLQVTYIEEAGTEADGSNVQSINTADDLLYMIYTSGTTGKPKGVLLEHKNMANLL
                     SHQLTNTDIDFCTNVLQYASLAFDVCYQELFSVLLSGGTLCIVPESIKRDVSQLFSFID
                     QHNTEVVFFPTAFVKMLFNEEGYAQSFPRCVKHVITAGEQLTVSRLFRQTLRLYGMHLH
                     NHYGPSETHVVSTYTISAGDDIPEQPPIGKPIHHNKMYILSKNRQLQPLGIAGELYISG
                     ANTGRGYVNNPALTEEKFLPDPFRTDAVMYRTGDLARLRADGQIEYIGRTDDQVKIR"
     CDS_motif       complement(3911..4000)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0009"
                     /evalue="1.20E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg21_1"
                     /protein_end="827"
                     /protein_start="797"
                     /score="40.0"
                     /tool="antismash"
                     /translation="PLGIAGELYISGANTGRGYVNNPALTEEKF"
     CDS_motif       complement(4109..4135)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0008"
                     /evalue="4.80E-01"
                     /label="NRPS-A_a5"
                     /locus_tag="ctg21_1"
                     /protein_end="761"
                     /protein_start="752"
                     /score="4.0"
                     /tool="antismash"
                     /translation="YGPSETHVV"
     CDS_motif       complement(4517..4573)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0007"
                     /evalue="5.30E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg21_1"
                     /protein_end="625"
                     /protein_start="606"
                     /score="28.2"
                     /tool="antismash"
                     /translation="YMIYTSGTTGKPKGVLLEH"
     CDS_motif       complement(4757..4798)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0006"
                     /evalue="3.10E-05"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg21_1"
                     /protein_end="545"
                     /protein_start="531"
                     /score="17.2"
                     /tool="antismash"
                     /translation="LGILKAGGAFVPID"
     CDS_motif       complement(5327..5443)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0005"
                     /evalue="4.70E-20"
                     /label="C67_DCL_14fromHMM"
                     /locus_tag="ctg21_1"
                     /protein_end="355"
                     /protein_start="316"
                     /score="64.1"
                     /tool="antismash"
                     /translation="QKDALKGQAYSYHPLYDIQANSQVKQGLIDHILVFENYP"
     aSDomain        complement(5483..6370)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_Condensation_DCL.1"
                     /domain_subtypes="Condensation_DCL"
                     /evalue="1.20E-113"
                     /label="ctg21_1_Condensation_DCL.1"
                     /locus_tag="ctg21_1"
                     /protein_end="303"
                     /protein_start="7"
                     /score="371.0"
                     /tool="antismash"
                     /translation="QDIYPLSYMQEGMLFHSLLQKESQAYAEQASFSITGKVDTRVFEE
                     SVHALFERHDIFRTIFISQNVSVPQQVVLKERNVSIIEENLTNLNKADQIKYIEEAKRR
                     DREKGFHLQKDMLMRVTLLQTGECEYTCIWSFHHIIMDGWCLGIVLKEFFQIYASRLRR
                     TPLTLEPAVPYGTYIKWLMEQDKEKAASYWERYLEGFEQQTVLPKQKKAGKSRQEEVTF
                     SFSKEDTAKLKELAVKEEVTLSTIFHTLWGILLQAYNQTEDAVFGSVISGRPSEIEGIE
                     RMIGLFINTVPVRIS"
     CDS_motif       complement(5489..5584)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0004"
                     /evalue="1.30E-19"
                     /label="C5_DCL_263-294"
                     /locus_tag="ctg21_1"
                     /protein_end="301"
                     /protein_start="269"
                     /score="62.6"
                     /tool="antismash"
                     /translation="DAVFGSVISGRPSEIEGIERMIGLFINTVPVR"
     CDS_motif       complement(5900..5965)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0003"
                     /evalue="5.70E-13"
                     /label="C3_DCL_135-156"
                     /locus_tag="ctg21_1"
                     /protein_end="164"
                     /protein_start="142"
                     /score="41.1"
                     /tool="antismash"
                     /translation="FHHIIMDGWCLGIVLKEFFQIY"
     CDS_motif       complement(6185..6298)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0002"
                     /evalue="9.00E-15"
                     /label="C2_DCL_024-062"
                     /locus_tag="ctg21_1"
                     /protein_end="69"
                     /protein_start="31"
                     /score="46.9"
                     /tool="antismash"
                     /translation="AYAEQASFSITGKVDTRVFEESVHALFERHDIFRTIFI"
     aSDomain        complement(6302..6391)
                     /aSDomain="NRPS-COM_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_1_NRPS-COM_Nterm.1"
                     /evalue="3.80E-19"
                     /label="ctg21_1_NRPS-COM_Nterm.1"
                     /locus_tag="ctg21_1"
                     /protein_end="30"
                     /protein_start="0"
                     /score="59.5"
                     /tool="antismash"
                     /translation="MTKKNAIQDIYPLSYMQEGMLFHSLLQKES"
     CDS_motif       complement(6320..6361)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_1_0001"
                     /evalue="1.00E-04"
                     /label="C1_DCL_004-017"
                     /locus_tag="ctg21_1"
                     /protein_end="24"
                     /protein_start="10"
                     /score="14.3"
                     /tool="antismash"
                     /translation="YPLSYMQEGMLFHS"
     CDS             complement(6417..10109)
                     /NRPS_PKS="Domain: AMP-binding (186-579). E-value: 4e-110.
                     Score: 360.0. Matches aSDomain:
                     nrpspksdomains_ctg21_2_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (684-752). E-value: 1e-24. Score:
                     78.4. Matches aSDomain: nrpspksdomains_ctg21_2_PCP.1"
                     /NRPS_PKS="Domain: Epimerization (761-1064). E-value:
                     3.1e-166. Score: 546.2. Matches aSDomain:
                     nrpspksdomains_ctg21_2_Epimerization.1"
                     /NRPS_PKS="Domain: TIGR01720 (1069-1223). E-value: 1.5e-51.
                     Score: 166.1. Matches aSDomain:
                     nrpspksdomains_ctg21_2_TIGR01720.1"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     343.3; E-value: 3.1e-104)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg21_2"
                     /sec_met_domain="AMP-binding (E-value: 4.7e-116, bitscore:
                     374.8, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-16, bitscore:
                     48.1, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 2.4e-78, bitscore:
                     250.3, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLEPILGMFVNTLAIRTEPKGDKRFTDYLAEVRQAALEAYEHQDY
                     PFEELVERLGVQRDMSRNPLFDVMFVLQNMERESLVLNKLHLAQAADTSHKTAKFDATL
                     YASEGSDGSISFDFEFNTDIYQKQTIEKWLSYFTRILTKVIENQAIPLGDIHVLDDAET
                     NRVIYQFNQTKSDYPRHETISRLFERQAKETPDARAVVYDGQILTYRELNERANRIAAA
                     LRSNGVGPESVVALLTGRTTELASGILGILKAGGAYLPIGDDVPRERAEWMLKDCKADI
                     LLQSDKLDGLPLSGKRLFIEDIQTKAGLSSENPEPLGGPESLAYMIYTSGSTGAPKGVM
                     IEQRSVIRLVKNSNYIDFTPKDRLLFTSSLGFDVTTFEIFGPLLNGASLYVSDQETYLD
                     SDVLETFIQQNGITTLWLTSSLFNHLSEQNEHVFSGLSRLIIGGEALSPSHVNRVRNAL
                     PHLSVWNGYGPTENTTFSTCFLIEQSYDHSIPIGRPVGNSTAYIINSRGTPQPIGVIGE
                     LCTGGDGMARGYFGRPELTEEKFVPNPFVPGERMYRTGDLARWLPDGAIEYAGRMDDQV
                     KIRGYRVELGEIEAALRSLDGVKEAAVSVRTGQSGNKELIAYMSLQADMDTEKVRSSLS
                     QQLPNYMIPAYMMELEKLPLTPNGKLDRKNLPEPELALQTAYTAPRNELEEQLSVIWQE
                     VLGTKQVGIEDSFFELGGDSIKALQVSARLGRYGWKMTASDLFRHPSIKELAPLIRKAE
                     RVIDQRPVEGDIPWTPVQHWFLSQRMENRNHFNQSVMMFSSDALQKQPLKEALEHLVIH
                     HDALRITVSEENESIRQINHGIQKAELYTLDIWDMSETDTWEREIETEVAALQQRMDIE
                     KGPLLKAGWFKTRSGDYLFITVHHLAVDGVSWRILLEDLSAAYTQAVKGQPVQLPPKTD
                     SFKQYAERLSEYAKSSKLMREEEYWRFIEEETAAELPYEKPQHQTGADSIRQTVSFTLT
                     EEETSVLLQQVNRAYHTDTQDILLTAAALALRDWTGGGRLRIAMEGHGREHIVPELDIS
                     RTVGWFTSMYPVLIDLNTAGSELGTAVKTVKDTLGRIPDKGIGYGILKYMTPPEQKTIR
                     FRQAPEISFNYLGQFNDTEDQHTFSLSGLASGHDITPTWQREQAVEMSAMAAQNKLHFS
                     LSYPPSRFSKETMEQLLQTLQQYLRDIMAHCTGKEESEKTVSDFSSKTLTSDDLDSIAS
                     FVEEL"
     aSDomain        complement(6441..6902)
                     /aSDomain="TIGR01720"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_TIGR01720.1"
                     /evalue="1.50E-51"
                     /label="ctg21_2_TIGR01720.1"
                     /locus_tag="ctg21_2"
                     /protein_end="1223"
                     /protein_start="1069"
                     /score="166.1"
                     /tool="antismash"
                     /translation="ELGTAVKTVKDTLGRIPDKGIGYGILKYMTPPEQKTIRFRQAPEI
                     SFNYLGQFNDTEDQHTFSLSGLASGHDITPTWQREQAVEMSAMAAQNKLHFSLSYPPSR
                     FSKETMEQLLQTLQQYLRDIMAHCTGKEESEKTVSDFSSKTLTSDDLDSI"
     aSModule        complement(6441..9551)
                     /complete
                     /domains="nrpspksdomains_ctg21_2_AMP-binding.1"
                     /domains="nrpspksdomains_ctg21_2_PCP.1"
                     /domains="nrpspksdomains_ctg21_2_Epimerization.1"
                     /domains="nrpspksdomains_ctg21_2_TIGR01720.1"
                     /locus_tags="ctg21_2"
                     /monomer_pairings="X -> D-X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       complement(6747..6776)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0011"
                     /evalue="3.90E-03"
                     /label="NRPS-E7"
                     /locus_tag="ctg21_2"
                     /protein_end="1121"
                     /protein_start="1111"
                     /score="9.8"
                     /tool="antismash"
                     /translation="PEISFNYLGQ"
     CDS_motif       complement(6816..6878)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0010"
                     /evalue="7.20E-10"
                     /label="NRPS-E6"
                     /locus_tag="ctg21_2"
                     /protein_end="1098"
                     /protein_start="1077"
                     /score="31.0"
                     /tool="antismash"
                     /translation="VKDTLGRIPDKGIGYGILKYM"
     aSDomain        complement(6918..7826)
                     /aSDomain="Epimerization"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_Epimerization.1"
                     /evalue="3.10E-166"
                     /label="ctg21_2_Epimerization.1"
                     /locus_tag="ctg21_2"
                     /protein_end="1064"
                     /protein_start="761"
                     /score="546.2"
                     /tool="antismash"
                     /translation="EGDIPWTPVQHWFLSQRMENRNHFNQSVMMFSSDALQKQPLKEAL
                     EHLVIHHDALRITVSEENESIRQINHGIQKAELYTLDIWDMSETDTWEREIETEVAALQ
                     QRMDIEKGPLLKAGWFKTRSGDYLFITVHHLAVDGVSWRILLEDLSAAYTQAVKGQPVQ
                     LPPKTDSFKQYAERLSEYAKSSKLMREEEYWRFIEEETAAELPYEKPQHQTGADSIRQT
                     VSFTLTEEETSVLLQQVNRAYHTDTQDILLTAAALALRDWTGGGRLRIAMEGHGREHIV
                     PELDISRTVGWFTSMYPVLIDL"
     CDS_motif       complement(6927..6974)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0009"
                     /evalue="1.50E-09"
                     /label="NRPS-E5"
                     /locus_tag="ctg21_2"
                     /protein_end="1061"
                     /protein_start="1045"
                     /score="29.7"
                     /tool="antismash"
                     /translation="DISRTVGWFTSMYPVL"
     CDS_motif       complement(7380..7445)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0008"
                     /evalue="2.10E-12"
                     /label="NRPS-E2"
                     /locus_tag="ctg21_2"
                     /protein_end="910"
                     /protein_start="888"
                     /score="39.1"
                     /tool="antismash"
                     /translation="LFITVHHLAVDGVSWRILLEDL"
     CDS_motif       complement(7644..7688)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0007"
                     /evalue="4.60E+01"
                     /label="C3_dual_135-156"
                     /locus_tag="ctg21_2"
                     /protein_end="822"
                     /protein_start="807"
                     /score="-2.4"
                     /tool="antismash"
                     /translation="HLVIHHDALRITVSE"
     CDS_motif       complement(7785..7811)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0006"
                     /evalue="6.50E-03"
                     /label="NRPS-E1"
                     /locus_tag="ctg21_2"
                     /protein_end="775"
                     /protein_start="766"
                     /score="9.8"
                     /tool="antismash"
                     /translation="WTPVQHWFL"
     aSDomain        complement(7854..8057)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_PCP.1"
                     /evalue="1.00E-24"
                     /label="ctg21_2_PCP.1"
                     /locus_tag="ctg21_2"
                     /protein_end="752"
                     /protein_start="684"
                     /score="78.4"
                     /tool="antismash"
                     /translation="EEQLSVIWQEVLGTKQVGIEDSFFELGGDSIKALQVSARLGRYGW
                     KMTASDLFRHPSIKELAPLIRKA"
     CDS_motif       complement(8343..8408)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0005"
                     /evalue="1.30E-12"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg21_2"
                     /protein_end="589"
                     /protein_start="567"
                     /score="39.5"
                     /tool="antismash"
                     /translation="YAGRMDDQVKIRGYRVELGEIE"
     aSDomain        complement(8373..9551)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg21_2_AMP-binding.1"
                     /evalue="4.00E-110"
                     /label="ctg21_2_AMP-binding.1"
                     /locus_tag="ctg21_2"
                     /protein_end="579"
                     /protein_start="186"
                     /score="360.0"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FERQAKETPDARAVVYDGQILTYRELNERANRIAAALRSNGVGPE
                     SVVALLTGRTTELASGILGILKAGGAYLPIGDDVPRERAEWMLKDCKADILLQSDKLDG
                     LPLSGKRLFIEDIQTKAGLSSENPEPLGGPESLAYMIYTSGSTGAPKGVMIEQRSVIRL
                     VKNSNYIDFTPKDRLLFTSSLGFDVTTFEIFGPLLNGASLYVSDQETYLDSDVLETFIQ
                     QNGITTLWLTSSLFNHLSEQNEHVFSGLSRLIIGGEALSPSHVNRVRNALPHLSVWNGY
                     GPTENTTFSTCFLIEQSYDHSIPIGRPVGNSTAYIINSRGTPQPIGVIGELCTGGDGMA
                     RGYFGRPELTEEKFVPNPFVPGERMYRTGDLARWLPDGAIEYAGRMDDQVKIR"
     CDS_motif       complement(8490..8579)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0004"
                     /evalue="1.10E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg21_2"
                     /protein_end="540"
                     /protein_start="510"
                     /score="49.6"
                     /tool="antismash"
                     /translation="PIGVIGELCTGGDGMARGYFGRPELTEEKF"
     CDS_motif       complement(9084..9140)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0003"
                     /evalue="1.20E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg21_2"
                     /protein_end="342"
                     /protein_start="323"
                     /score="30.1"
                     /tool="antismash"
                     /translation="AYMIYTSGSTGAPKGVMIE"
     CDS_motif       complement(9327..9365)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0002"
                     /evalue="1.60E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ctg21_2"
                     /protein_end="261"
                     /protein_start="248"
                     /score="15.1"
                     /tool="antismash"
                     /translation="LGILKAGGAYLPI"
     CDS_motif       complement(9894..10013)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg21_2_0001"
                     /evalue="3.80E-24"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ctg21_2"
                     /protein_end="72"
                     /protein_start="32"
                     /score="77.2"
                     /tool="antismash"
                     /translation="RQAALEAYEHQDYPFEELVERLGVQRDMSRNPLFDVMFVL"
ORIGIN
        1 tctcctccag ccggccgcgg tcaagcgggc ccgtcagttc cagcacagcc ggcatattgt
       61 agccgacacc gccgtcttca agctgctgga gcacatacat ccgtttctgc gccgaagaca
      121 ccgggtagat gtcctgtgtt tgcgcaggct gaatcgcttc atacgggctc tcttccaagt
      181 cctgaataac cgaagcgagc tcttccaccg tcggccgggc gaagatatcc tgcaacggca
      241 cctgaacacc gaactctttg gcgatgcggg agacgagagc cgtcgctttt aacgaatggc
      301 cgccccgctc aaaaaagtga tcccggatgc cgaccgggcc gtttttcagc acctcttccc
      361 aaagggcgca aagcttcatt tccgtgacgt tccgcgggac ggtgtacgcc tgtctgtctg
      421 ccgctccgcc gggagccggc agcgcgcggc ggtcaagttt tccgctcggc gtgaccggcc
      481 actcggtcat ctttatgaac tgagccggca tcatgtaggc cggaaggcgt gtcgcaagct
      541 ccgcccgcac gtcatcgctt tcccgtcctt cgatataggc gtaaagcgcg gtttcgccgt
      601 gttcggtccg ggcggtgacc gccgcctcac gaatgccgtc gatgcgccgg atcgccgctt
      661 cgatttctcc cggttcaatc cggtagccgc ggactttcac ctgtccgtct gaacgcccga
      721 gccattcaac aaggccgtct tctgtccagc gtgcgatatc gcctgtctga tacatgcgct
      781 ctcccggata aaacggatca tcgagaaagc gctcctccgt cagctcaggc cggttcagat
      841 agccccgggc cacccctgtc cccgcgatgt acagctctcc gatacagccc ggcggcagaa
      901 gctgtttctt ttgatttaaa atatacagcc gcatgttatg tccggaaatg ccgatcggaa
      961 cattgtgaaa ttcttttcct tgcggcaaat caaagtacgc cgcttctact gtcgcttccg
     1021 tcggaccgta ggaatttgtc aattccgttc ccggcagaag gtcataaaaa cgggaagcca
     1081 ggtgcgggcc caattgttcg ccgccggcaa aaaccctttt taagcaggtc tttttgatcg
     1141 gctgttttct ggaatttata tattccaaga aagcatgaag catggatggc acaaaatggg
     1201 ccgctgttat gcggttattc tccaatgcgt tcagtatcat ttcagggtcc ttttcgcctc
     1261 cttgcggaag gaggaaaaca gaagctcccg cgatcggcca ccaaaacagc tcccaaatcg
     1321 aagcgtcgaa agagtatgat gttttatgca aaatgatgtc agaatcactt aatccataac
     1381 gcgtttgcag cgagtataaa aagtttacgg ctgactgatg ttcaacctgc acgccttttg
     1441 ggcgtcccgt agaaccggat gtatagatga tataagccaa tgaatcaggt tttaccggaa
     1501 cattggggtt ggccgcagct tcagggtttc ctgtttgtcc gcttttcaga gagatcattt
     1561 ctccctcaaa aagatctgca gccaaaagtt ctggttctgc cagtaagaat ttcacgccgc
     1621 tgtctttcag taaaaagcga atccgctctt tggggtaatc cggatcaatc ggcagatatg
     1681 caccgcctgc ttttaagaca gcgtaaatgc cgatcagcat gtcaggagaa cgccggccca
     1741 taatggcagt tttatcctcc agccttatcc cccgcttgat cagccggtgc gcaagctcat
     1801 tcgctctttc gttcagctct tgatacgtaa tcgaaatgtc atcagttaaa attgccggac
     1861 ggtccggcgt tttttccgcc tgctgttcca gcagatcatg aagaggctga tgaagcggaa
     1921 acgctgtttt ctgcaagggg ctgaaatctt gaagcagaga cgcttcttct ttttctgtca
     1981 aaacagaaat atcgtctaat tccaagcccg gatcagccgc ggcgttttcg gcaagtgtcg
     2041 taaaaaattc ggcccatttt tgaatcgttt ttctcttaaa caaatcggtg ctgtattcaa
     2101 actggcagta caattcaccg gcgttttcag agatgtacag cgataagtca aatttagaaa
     2161 tcggcaggct gacgtctgcc ggctgcagtt caagtccgga tgccctaagc ttctgctgtt
     2221 ccatattttg cagcgcaaat gttgtgtcaa acagcggatt tcgggacatg tcccgcggca
     2281 caccgagctt atcgacgagc tcttctaacg ggtaatcctg atgttcgtaa gcctcaagcg
     2341 ctgtttggcg aatttccttt aaatattctt tgaatgtcat gcttccgtcg ggacgcgtcc
     2401 tgaaagcaag catattgaca aacatgccca gaacggcgtc aaggtcggca tgaggccttc
     2461 ctgcaatcgg agacccgacg atcatatctt cctgtccgct taaacgggct aacagaaccg
     2521 tgtacacacc aagcagcgtc atatacagtg tgcatttgtt ttctttcgcc agctttttca
     2581 actgtgctgt atgtttttcg ctgatgacaa atgacacccg gtcaccggaa aagctccgca
     2641 ccgggggacg cggcttatca gccggcaatt caagcacggg aatctccccg gctagccggt
     2701 tcagccagta ctcctcttgt ttccgatatg cggcgcccgc cataaatgat tgctgccaga
     2761 cggcataatc tttgtattga atccgtaacg gcggcagact tctctcagca tacagctcac
     2821 tgaattcacg tatcaaaaga ttgacggata cgccgtctga aataatatga tgcatgtcag
     2881 ctaaaagcag atgccggtct ttttctattt ggacaaatcc cgcccggaaa aggggcgctt
     2941 tgccgagatc gaacggccgg ataaacgctt cggctgattg ttcttttgta aatgcaaacg
     3001 gcacttcgtc atgaattctc tgcacgggca ggccgttttt ttcttcaaag gacgttctga
     3061 gcggttcatg ccgccagatc aattccttga acacggcttc catcctgtct cggtcaaacg
     3121 gccccttcac ctctaaaacg gctggaatgt tatagctgac accgccattt tcaagctggt
     3181 gaaggacgta catccgtttt tgggcggatg agacaggata tgtttctttc gtttctgtct
     3241 tttctatgga tgcgaacggg ttctcttctg cttcactgat gattttggcg agttcttcta
     3301 cagtcggatg gctgaagaca tcgctcagcg ggatttgcac actgcactct ttagctattt
     3361 ttgcaacgag tgccgtcgcc tttaatgaat ggccgccaag ctcgaaaaag tgatcgtgaa
     3421 cgccgatcgg gctggtttga agcacttctt cccatatacg ggtaagcttc agctcggtca
     3481 cattccgagg agctgtatat cgacggcccg ctgcgtacgc cgaagcttct ggaagagccc
     3541 gctgatcgac ttttccgttc gcagtgagcg gaatcgagtc aacgaaagcc catttgaccg
     3601 gaatcatata atcaggcagc tctttagcca aatctcttcg cagctgagaa ggatcagtcg
     3661 cttgtgagac gctgcagtaa gcgcataatt cattttcgcc cgactcattc gtttgaatca
     3721 gaacggcagc ttctttcacg gcatgatgat ttgccaggac ggtttcaatt tccttcggtt
     3781 caatccggta ccctctgatc ttcacttgat catctgtccg gccgatgtat tcaatttggc
     3841 cgtccgcacg cagtcttgcc aaatctccgg tccggtacat gacggcgtcc gttctgaacg
     3901 gatcgggcaa aaatttctct tcggtcagcg ccggattgtt cacatagcct cttcctgtat
     3961 tcgctccgga aatatacaat tctcccgcaa ttccgagagg ctgaagctgc ctatttttgc
     4021 tgagaatata catcttgtta tgatggatcg gtttcccgat cggcggttgt tcaggtatgt
     4081 catctcccgc agaaatcgta tacgttgaaa ccacatgagt ttctgacggg ccgtaatgat
     4141 tatgcagatg cataccgtat aaacggagcg tctgcctgaa caaacgcgaa acggtcagct
     4201 gctccccagc cgtaatgaca tgcttcacac agcggggaaa agactgtgca taaccttctt
     4261 cattgaaaag catcttgaca aacgcagtcg ggaaaaacac cacttccgtg ttgtgctgat
     4321 caataaacga aaacagctga gaaacatccc gtttgattga ttccggcacg atacagaggg
     4381 tgccgccgct caagagtact gaaaataact cctgatagca gacgtcaaac gccaaagatg
     4441 cgtactgcag cacatttgtg caaaaatcaa tgtctgtgtt cgtcaattgg tgagaaagca
     4501 ggttggccat atttttatgt tcgagcagca cgcccttcgg tttccctgtc gtaccggatg
     4561 tataaatcat ataaaggagg tcgtccgccg tattaatgga ttgcacattg cttccgtccg
     4621 cttccgtccc ggcctcttct atgtatgtaa cttgcagcgt ttgttccgcg gggactgact
     4681 gatgccgctc tgttacaaca tggacgcagc cgctgttttc aatgacatat cggatacgct
     4741 cctttggact gcccggatct atcgggacaa aggcgccgcc cgcttttaaa ataccgagaa
     4801 cagccgccgc taaagaaggg gaacggccga gcatgacgcc taccggctcc tcccgcttta
     4861 aaccgcgttt tttcagcagg cgtgccagct tattagccga ttcgttcagc tctttgtacg
     4921 tcactgactc accttcatac cgaatcgcga tttgatccgg cgtttttgcg gcctgccgtt
     4981 caaacattgc atgaaccgtg tcatattcag gcttttcggt ctcttcagaa atcggcgcaa
     5041 gcagctgcac tttttcccct ggagtgatga tttcaagctt gtccggcgtg atgtccggtt
     5101 tgtcgagaac ttgggagacg atgtgtgcca aatggccttt gatattttcg ataaattggc
     5161 ggtcatacac gcttgaatcg aatctcattt tcaagtgaat ctcgtcaccc ggcgccacca
     5221 tcaggtaaaa actgtaattg gtttcgtctt ccatgctgaa atcatggatg tgaaaaaggt
     5281 ctttcgtgtc ccccttgctg ttcagcacat caagctcctg ttcaaccgga taattctcaa
     5341 agacgagaat gtggtcaatt aagccttgtt ttacctgtga attcgcctgt atgtcataaa
     5401 gcggatgata gctgtaagcc tgtcctttca aagcgtcctt ttgcacgttt ttgatcagct
     5461 tttgaaacgg gatgtccgcc ccgctgatcc ggacaggcac ggtattaatg aacaggccga
     5521 tcattcgctc gatgccttcg atttcagacg gccttccgga aatgacagaa ccaaaaaccg
     5581 catcttctgt ctggttatac gcctgaagca aaatgcccca gagcgtgtgg aaaatggtgc
     5641 tcagcgtgac ctcttctttt acggccagct ctttcagctt agccgtgtcc tcttttgaaa
     5701 aggaaaacgt cacttcctct tgtctgcttt taccggcttt tttctgcttc ggcagtacag
     5761 tctgctgttc aaagccttca agataccgct cccagtacga agcggctttt tctttatctt
     5821 gctccatcag ccacttgatg taggtcccgt acggcacagc aggctcaagc gttaacggtg
     5881 tccggcggag ccgcgaggcg tatatctgga agaactcttt cagcacgatt ccgagacacc
     5941 agccatccat aatgatgtga tggaaactcc atatgcacgt atattcacat tctccggttt
     6001 gaagcagcgt cacccgcatc agcatgtctt tttgcagatg aaaccctttc tcacggtctc
     6061 ttcgtttggc ttcttcgata tacttgattt gatcagcctt atttaaatta gtgagatttt
     6121 cctcaataat gctgacgttc cgctctttta atacaacctg ctgcggcacg gacacgttct
     6181 ggctgataaa gatcgttctg aaaatatcat gtctttcgaa aagggcatga acgctctctt
     6241 caaacacgcg ggtgtcaacc ttccccgtta ttgaaaagga ggcctgctcg gcgtaagcct
     6301 gtgattcctt ttgcaggagg gaatgaaaaa gcattccttc ctgcatataa gacagcggat
     6361 aaatatcctg aattgcattc ttttttgtca tgttataatc tccccgtcgc ctttttctac
     6421 agttcctcga caaaactcgc tatgctgtcc aaatcatcag atgttaacgt tttgctgcta
     6481 aaatcactaa cggttttttc tgattcctct ttgccggtgc agtgcgccat aatatcacgc
     6541 aaatattgct gtaaggtttg cagcagctgt tccatcgttt ctttggagaa gcggctcggc
     6601 ggatagctca aactgaagtg aagtttgttt tgtgcggcca tcgcgctcat ttccaccgct
     6661 tgttcccgct gccatgtcgg cgtgatgtcg tgcccgctcg cgagaccgga cagactgaac
     6721 gtgtgctgat cttctgtatc attgaattgc cctaaatagt taaagctgat ttcaggcgct
     6781 tgtctgaagc ggattgtttt ttgttcaggc ggtgtcatgt attttaaaat gccgtagcct
     6841 attcctttat ccggtattct tccgagtgtg tctttgaccg tttttaccgc cgtcccaagt
     6901 tctgagcctg ctgtattcaa gtcaatgagc accggataca tggaggtaaa ccagcctacg
     6961 gtgcggctga tgtcaagctc cggcacgatg tgctctctcc cgtgcccttc catcgcgatg
     7021 cgcagtctgc cgccccctgt ccagtcccgt aaagccaaag ctgcggcagt cagaagaata
     7081 tcttgcgtat cggtatggta ggcccggttg acctgctgaa gcaaaacgga cgtttcttct
     7141 tctgtaagcg taaagcttac cgtttgccga atgctgtcgg ctcccgtctg atgctgcggt
     7201 ttttcataag gaagttcggc ggctgtttct tcttcaataa aacgccaata ttcttcttca
     7261 cgcatcagct tgctgctttt tgcgtattcc gaaagccttt cagcgtattg cttaaacgaa
     7321 tcggtctttg gcggaagctg gaccggctga ccttttacgg cttgagtgta agcggcagat
     7381 aaatcctcca gcagaatacg ccatgacact ccgtcaaccg ccaggtgatg tacggtgatg
     7441 aataaataat ccccggaccg ggttttgaac cagccggctt ttaataacgg ccctttttca
     7501 atatccatcc gctgttggag cgcagccact tcagtttcta tttctctttc ccaagtatct
     7561 gtctcagaca tatcccaaat gtccaaggtg tacagttcag ctttttgaat accgtgattg
     7621 atttgtctga tactttcgtt ttcttcactg acggtgatcc ggagtgcatc atgatgaatg
     7681 acaaggtgct ccaaggcttc tttgagcggc tgtttttgca atgcgtcaga gctgaacatc
     7741 atgacggact gattgaaatg atttctgttt tccatccgct gtgataaaaa ccagtgctga
     7801 acgggtgtcc aaggtatgtc tccttccacc ggccgctgat cgatgactct ttccgctttc
     7861 cggataagag gcgcgagttc cttaatggac ggatgccgga ataagtcact tgccgtcatt
     7921 ttccacccat agcgtccgag ccgtgcggaa acttgcagcg ctttgattga atcgccgccc
     7981 aactcaaaaa atgagtcttc aatcccgact tgttttgtgc cgagcacttc ctgccaaatc
     8041 acggaaagct gttcttcaag ctcattgcgg ggagctgtgt acgcggtttg aagcgcgagc
     8101 tccggttcgg gcagattttt ccgatccaat ttaccgttcg gcgtaagcgg cagcttctca
     8161 agttccatca tataggccgg aatcatgtaa ttcggcagtt gctgagaaag tgaagaacgc
     8221 actttttctg tatccatgtc cgcctgcaga ctcatatatg cgatcagttc tttattgccg
     8281 gactgcccgg ttctgactga cacggcagct tctttcacac cgtccaggct cctcagtgcg
     8341 gcttcaatct ctcccagctc gacccgataa ccgcggattt tcacttgatc atccatccgc
     8401 ccggcatatt cgatcgctcc gtccggcagc cagcgggcta aatctccggt gcggtacatc
     8461 cgttctccgg gaacaaaagg attagggaca aatttttctt ccgtcagctc agggcggccg
     8521 aaatatcctc ttgccatacc gtctccgcct gtgcacaatt cgccgatgac gccgatcggc
     8581 tgcggtgttc ccctgctgtt tatgatatat gcggttgaat ttccgacagg gcgcccgatc
     8641 ggtattgaat gatcgtatga ttgttcaatc aaaaagcaag tcgagaacgt cgtgttttca
     8701 gtcggtccgt atccattcca tactgagaga tgcggcagcg cattccgaac ccggtttaca
     8761 tggctcgggg acagtgcttc cccgccgata atcaatcggg ataatccgga aaacacgtgt
     8821 tcattttgtt ctgataaatg gttgaacaga gacgatgtca gccacagtgt cgtaatgccg
     8881 ttttgctgta taaatgtttc cagaacatca gagtcgagat aggtttcctg gtcacttaca
     8941 tataaagaag cgccgtttaa aagcggaccg aatatttcaa atgtcgtaac gtcaaatcct
     9001 aatgatgaag taaacaacag tctgtctttc ggcgtaaaat caatataatt gctgtttttc
     9061 acaaggcgga tcacgcttcg ctgttcaatc atgacgcctt ttggcgcacc tgttgacccg
     9121 gacgtataaa tcatgtaggc caacgattca ggtccgccga gcggttcggg attttccgaa
     9181 ctcaagccgg cctttgtttg aatatcctct atgaataaac gttttcctga aagcggcaga
     9241 ccgtcaagtt tatcagattg gagaagaata tcagctttac agtctttaag catccattca
     9301 gcccgttccc gcggcacatc gtcaccaata ggcaagtagg cgcctcccgc ttttaatatt
     9361 ccgaggattc cggaagcaag ctctgttgtg cggccggtta ataaggcgac aacgctttcc
     9421 ggaccgacgc catttgatcg gagagccgca gctattctgt tagcccgttc gttcagctca
     9481 cggtatgtca agatttgtcc atcatataca actgcccggg catcgggggt ttcttttgcc
     9541 tgccgctcaa ataaacggct gatggtttcg tgtcttgggt aatcgctttt cgtctgatta
     9601 aactgataaa tgacgcgatt tgtttcagca tcatccagta catgaatgtc accaagcggt
     9661 atcgcttggt tttcaattac ttttgtaaga atacgggtaa aataagaaag ccatttttca
     9721 attgtctgtt tttgatagat atctgtattg aattcaaaat caaagctgat ggaaccgtca
     9781 gacccttctg acgcgtaaag cgtggcatca aactttgcgg ttttatgact tgtatccgca
     9841 gcttgagcca aatgcagctt atttaacacc agggattcac gctccatatt ttggagcaca
     9901 aacataacgt caaacagcgg attgcggctc atgtcccgct gcaccccgag ccgctccaca
     9961 agctcttcaa acgggtagtc ctgatgctca tacgcttcaa gcgcggcctg gcggacttcc
    10021 gccaagtaat cggtaaaccg tttgtctcct ttcggctccg ttctgatggc gagcgtgttg
    10081 acgaacatgc cgagaatcgg ttcaaggtct t
//
