LOCUS       gnlProkkaCGPGODHF_44   12148 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CGPGODHF_44.
ACCESSION   gnlProkkaCGPGODHF_44
VERSION     gnlProkkaCGPGODHF_44
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 09:45:15
            Original ID  :: gnl|Prokka|CGPGODHF_44
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 39515
            Orig. end    :: 51663
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12148
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7148]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..7148
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..12148
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12148
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             642..2192
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1249:carbamoyl phosphate synthase small subunit
                     (Score: 384.9; E-value: 5.4e-117)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_40"
                     /transl_table=11
                     /translation="MTTMTKLVNEMILVLDFGSQYNQLITRRIREFGVYSELHPHTLTA
                     EEIKEMNPKGIILSGGPNSVYDEGSFRCDEKIFELDIPVLGICYGMQLMTHYLGGKVEA
                     ASQREYGKANIQIQGTPDLFKDLPEEQVVWMSHGDLVVQVPEGFTVDATSHHCPNSAMS
                     KKDKKWYGVQFHPEVRHSEYGNDLLKNFVFGPCECKGEWSMENFIEIEMQKIRETVGDK
                     QVLCALSGGVDSSVVAVLIHKAIGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFNMNVIK
                     VDAKDRFLNKLKGVSDPEQKRKIIGNEFIYVFDDEADRLKGIDYLAQGTLYTDIIESGT
                     ATAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTELGIPDDIVWRQPFPGPGL
                     GIRVLGEVTEEKLEIVRESDAILREEVANHGLERDIWQYFTVLPDIRSVGVMGDARTYD
                     YTIGIRAVTSIDGMTSDWARIPWDVLEVISTRIVNEVKHINRVVYDITSKPPATIEWE"
     CDS             2556..3818
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 72.2; E-value: 7.2e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_41"
                     /sec_met_domain="ATP-grasp_3 (E-value: 4.8e-14, bitscore:
                     45.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 4e-09, bitscore: 29.4,
                     seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 5.6e-08,
                     bitscore: 25.7, seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHILFFNATYIKKISTLETAKNLGLTVSVVGPELPEWSRPFVD
                     HYISANTYQIDETIAVLKETAKENPFDGVITFWDRDVVPVAVTARELNLKGSPVEAAER
                     ARNKWKMRQFLNRAQVPHPKYCKFTNWTELYHASIDMEYPLIVKPVGASASKGVFRISK
                     PEDLNRAYQQLLNAAVPENDKMFSFYQNEYIVEEFMNGQEVSIEGVISDGVIHFAGVTE
                     KWTDQYFEEYQHAFPARLPEAVERELFHITSEGIKALELNNCGFHAEVMITEKGCKIIE
                     INGRLGGDFITTHLVPLAKGINITRANLLAVLGETISFEASKRRAACVRFLIADRAGVI
                     EKWEGVESIKEMPGVVEFVLEKQPGDHVGLPPEKFHDSRIAYVITEAEDTEKAIEYAEN
                     ALSEVRCFINGEEKTVPDRDS"
     CDS             3781..4992
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg34_42"
                     /sec_met_domain="ATP-grasp_3 (E-value: 8.8e-17, bitscore:
                     54.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 5.2e-07, bitscore: 22.6,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 4.2e-11,
                     bitscore: 35.9, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 2.8e-10, bitscore:
                     33.2, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKRLFLIGIPETHIEKAVTRAKQLGFDVLLGDTEASLKKYEHL
                     IKEADQKIALDYTNHENLFSVAKEIHDKEPLDAIFTFKEAGLFNVSKLQQAFHLKGNPP
                     SVVQACLDKYTTRRLLKKAGLNSPDFGLCRSVEDVYDFWNTSQHPIILKPRSQQGSIGV
                     IKVEKKEDIEACFKECSKHDEEKSVLAEEFIEGQEISIEAVVCQGKVDIFGVTEKLLYP
                     GTFVESGHISPYKHKEKHQDLYKNLVKEVVHAMGIVFGPLHIEGYHTNKGFVVGEVHTR
                     YGGDNIVTITEIAMKCDMHTPIFAELAGIPYQPERKHAQSEVCAVRFLETNQGVVRAIK
                     GISDLKMMGNVVDFHVNCSVGDRIRPIKNSYDRAGWMIVKGKNEREVNHALHDAIDKIK
                     IIIR"
     CDS             5001..5891
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) phosphonates-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 264.8;
                     E-value: 1.6e-80)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_43"
                     /sec_met_domain="phosphonates (E-value: 1.2e-109, bitscore:
                     359.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates-like (E-value: 1.2e-127,
                     bitscore: 417.8, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 7.9e-69, bitscore:
                     225.0, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMVKNRKSSIFRDALNSKGLVKVAGAHDGLSAKLAEKNGFNAVWA
                     SGLGISAVQTVPDASILTMTEFLEAAVIMNESCNLPVIADCDSGYGNIHNVTRMIKKYE
                     AAGIAGVCIEDKVYPKLNSFDDRQQILVSTEEFCAKIRAAKMAQQNDDFVLIARVEALI
                     AKLGQEEAYTRAKAYVHAGADAILIHSKEQSPDEIIEFVNNWDVDAPLVVVPTKYPTLS
                     MEQLEKLGVKVSIYANQALRASVKAINDTFESIINNKSSLQIENDIVSVNEIFDIQDVP
                     GMKQLERLIHRQPAN"
     CDS             5949..7148
                     /NRPS_PKS="Domain: Aminotran_1_2 (32-388). E-value:
                     1.9e-69. Score: 226.3. Matches aSDomain:
                     nrpspksdomains_ctg34_44_Aminotran_1_2.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 287.8; E-value:
                     2.2e-87)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg34_44"
                     /sec_met_domain="Aminotran_1_2 (E-value: 5.5e-69, bitscore:
                     226.2, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3.7e-11,
                     bitscore: 36.0, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKRLSDRVMNIKPSATMSLNAKTKIMVKEGKDIINMSVGEPDLH
                     PPLTASYAGIQAIVKGKTGYTPAAGLIELRESIVRYLLNERGLEYKPNQIIASAGGKQP
                     LYNVFQAICDQDDEVILPSPYWVSYPEQIKLSGAVPVIVSCDETTNFKITPEKLAEVIT
                     PKTKAVVITSPNNPTGSVYSENELKALGNVLKDYSEIFIISDEIYDQFVYEGKHISLPL
                     IFPELLNRTIITNGFSKVFAMTGWRLGYIAAPSDIAEAIASFQSHATGSPSTISQYAGI
                     SALNGFDKSMVEEYKKRRDILVDGLNQIEGIQCAKPNGAFYAFPNVSQFFGTMFEDQQI
                     IDAETFCHLLLEKQHVSAVPGTAFGEPNNIRLNFAIPKDLITEALKRINNFTTQLAVKV
                     "
     aSDomain        6045..7112
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg34_44_Aminotran_1_2.1"
                     /evalue="1.90E-69"
                     /label="ctg34_44_Aminotran_1_2.1"
                     /locus_tag="ctg34_44"
                     /protein_end="388"
                     /protein_start="32"
                     /score="226.3"
                     /tool="antismash"
                     /translation="DIINMSVGEPDLHPPLTASYAGIQAIVKGKTGYTPAAGLIELRES
                     IVRYLLNERGLEYKPNQIIASAGGKQPLYNVFQAICDQDDEVILPSPYWVSYPEQIKLS
                     GAVPVIVSCDETTNFKITPEKLAEVITPKTKAVVITSPNNPTGSVYSENELKALGNVLK
                     DYSEIFIISDEIYDQFVYEGKHISLPLIFPELLNRTIITNGFSKVFAMTGWRLGYIAAP
                     SDIAEAIASFQSHATGSPSTISQYAGISALNGFDKSMVEEYKKRRDILVDGLNQIEGIQ
                     CAKPNGAFYAFPNVSQFFGTMFEDQQIIDAETFCHLLLEKQHVSAVPGTAFGEPNNIRL
                     NFAIPKDLITEALKRI"
     CDS             7213..8445
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 255.4; E-value: 1.1e-77)"
                     /gene_kind="transport"
                     /locus_tag="ctg34_45"
                     /transl_table=11
                     /translation="MKGIRLRIHPVGWNIILGTLFSRMSVSMSIPFLSIYLTQVKGVSP
                     ALTGIIVSVSSLAGIVMSFYGGYLSDLFGRKIVMITSVFCWALVFVSFMFADSVLAFFV
                     INALNGLCQSIFEPASRALLSDISKEENRLKMFNLRYTAINIGVVFGPLLGLRLGAAKT
                     ALPFLFAGFTYFLYGLSLLFSFRKFKLDENNRKENKTTIATAFNVTRKDKVFLITLLGV
                     ILSISGYAHFSTTLPQYFAAKIEDGVTIFSWLLALNAIVVLIVQYPIVNIMKKFPPIHS
                     IILGNALISFSLLFFSLSSNPFIWGSIVVFFTIGEVLIFSMVDMLVDEIAKPGFKGTYF
                     GAAGFNRLGNVIGPWLGGILLSFFGVNGSFYMFLIIFITTASGIPVLFLAKKHLDKSGH
                     SKVDVTESHRS"
     CDS             8764..9297
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 106.1;
                     E-value: 2.6e-32)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg34_46"
                     /transl_table=11
                     /translation="MKEERLIKKAKKGDAAAFEKLITAHQETLYKTAYLYLHHKEDTLD
                     AVQETAYKAFLHIAQLKEPKYFKTWLIRILLHTIFAMRKKHGDVIPFEPQHDTRAENKN
                     IEEYIDLRNALETLDEHIQLTIQLYYFQDFSIAMIAEQTGMAEGTVKTHLHRARKALKQ
                     ELEKEDKHIWKSIK"
     CDS             9279..10721
                     /locus_tag="ctg34_47"
                     /transl_table=11
                     /translation="MEKHQMKQLYQDIDVPKAELKNVIHSAAVRVGKEGAVRRRWGRKL
                     INGLAVAAALFILYLSSGLFMPSVNTAMGNIPVAGQIYSLFQDKAGSALFKSNLVTKLN
                     EKAESRGITVTVKSVYYDSGQLVYNFTVDNLKSDEESISFQVDYKDPWNMLAEDYDNSN
                     MKKMKDGQYAGQLRLFTDGSKLKDGDKLPLVITQIKDIPGNWRFTLPIKKQKSVSLEGT
                     KAVNVNHGLYRFFDIRAENGTTGSALLYSIDFYDAAKNDAISIYEATDDAGNHYEMTAS
                     NIELGGRKNLPGGGKRIRGQTQFSKPIDPKAKTLFITGDIKTESEPGEIVPLKTKLPVS
                     YKTKHHHVGITVKKIKQQGRRVIVDYQFTGINYSKADEDQLINVGESIGLGNTKKMKTW
                     PSLNEYEKGYYLKGNKAKVTNLKTGEMESVFELDDSSNKDYSLRDFSFDSYALYVNQTV
                     MNLLADDKGITFAVPVRPADGK"
ORIGIN
        1 cagcggggaa ctcggatgaa ccgtctgaca agcagcgtca ggaaacaaag ccggaaaaag
       61 aggaaaagcc gaaaaagcgg gatcacagcg cggcaccgca gcctgtgatc cgcaacaaaa
      121 ccgcggcaca gctatggccg tatgcagcca tcgtcattgt gatttcagcc gcggcggcac
      181 tcgcctggct gctccgggcg cgctggattc cgcacgttac agcagccaga ttgaagcggc
      241 gaacggatga agacgtcttt ttcgacgcat atgccgcact gctccgacag ctgaaacgaa
      301 aagggttcag caggggagac ggagaaacgc tccgtgattt tgccgcgagg gttgacgagg
      361 cgcaccatac aaacgacatg tccgagctga cgctgcgcta tgagcgtgcg ttataccgca
      421 gcgataatgc cgcaaagctt tggaatgaat cgggacagtt gtgggaaaat ataattaaaa
      481 gaagatagtc ttgaccgcat atcgtcctgt tgttagaata aatgaatgtt aaatgggagc
      541 ccgggagcgt taaaaagccg ggcttccgga caagtcttgc cgacagaggg ctgaacgtgt
      601 gtcctccgtt ttttctgtgt caaaaactta gaggagatta ggtgacaacc atgacgaagt
      661 tagtgaatga aatgattctt gttcttgatt tcggcagtca gtataaccag ctgattaccc
      721 gccggatccg tgaatttggc gtatatagcg agctgcatcc ccatacgttg acagctgagg
      781 aaatcaaaga aatgaatcca aaaggaatta tcctttcagg cggaccaaac agtgtatatg
      841 atgaagggtc tttccgctgt gatgaaaaaa tctttgaact tgatattcct gtattaggca
      901 tctgctacgg catgcagctg atgactcatt acctcggagg gaaagtcgag gcggcaagcc
      961 agcgcgaata cggaaaagcg aacattcaga ttcaaggaac tcctgacttg ttcaaagatc
     1021 ttccggaaga acaagttgtc tggatgagcc acggcgactt agtcgtacaa gtgccggaag
     1081 ggtttacggt agacgcgaca agccatcact gcccgaactc ggcgatgagc aaaaaagaca
     1141 aaaaatggta cggtgttcag ttccatccgg aagtccgtca ttcagaatac ggaaatgacc
     1201 ttctgaaaaa ctttgtcttc gggccttgtg aatgtaaagg cgaatggtca atggaaaact
     1261 ttatcgaaat cgaaatgcaa aaaatccgcg aaaccgtcgg agacaaacaa gtgctttgcg
     1321 ctttgagcgg cggagtcgat tcttctgtcg tagccgtttt gattcataaa gcgatcggcg
     1381 accagctgac ttgtattttc gtagatcacg gccttctccg caaaggcgaa gcggaaggcg
     1441 tcatgaaaac gttcagcgaa ggctttaata tgaatgtcat taaagttgat gcgaaagaca
     1501 gattcttaaa caagctgaaa ggtgtttctg atcctgagca aaaacgcaaa atcatcggca
     1561 acgaattcat ttacgtattt gatgatgaag cggacaggct gaaaggaatc gactaccttg
     1621 cgcaaggaac gctttacaca gacattattg aaagcggaac ggcaactgcg caaacgatca
     1681 aatcgcacca caatgtcggc ggacttcctg aagatatgca gtttgaactg atcgaaccgc
     1741 tgaacactct tttcaaagat gaagtgcgcg cgctcggcac agagctcggc atcccggatg
     1801 atatcgtatg gcgtcagccg ttcccgggtc ctggacttgg catccgcgta ctcggcgaag
     1861 taacggaaga aaaacttgag atcgttcgtg aatcagacgc gattctgcgt gaagaagtgg
     1921 cgaaccacgg ccttgagcgc gacatctggc agtacttcac ggttcttcct gacatccgca
     1981 gcgtcggcgt catgggagat gcgagaacgt atgattacac aatcggtatc cgtgccgtaa
     2041 catcaatcga cggcatgaca tctgactggg cgcgtatccc ttgggatgtg cttgaagtga
     2101 tttcgacacg gatcgtcaat gaagtgaaac acatcaaccg cgtcgtgtat gacattacga
     2161 gcaagccgcc tgcaacaatt gagtgggaat aatgagaaaa gcctcaaatc ttttatttat
     2221 aaagatttga ggctttttta atttacatgg ttctaggaat aatgggcctt ttatcattaa
     2281 caccggagaa gatgtgcagc agttttttat atattcgagt tttttaatca gttgtattcc
     2341 taatattctc cctataattt caatttttct aataaaactg aattcataaa atattcattt
     2401 aataacaaat aatgtatgtt attatgaata tatacaaata aaacatatga tggtttgtgt
     2461 tttccaaggg gtttttttat cttctgcatt cagttcttta gaaacgcaga aggtttctaa
     2521 tttgtagaaa aaaatgttga aagaggctcg gaaggatgga aaaacatatt ttatttttta
     2581 atgctactta tattaaaaaa atttctactt tggagactgc taaaaatttg ggcttgacgg
     2641 tttctgttgt cggccctgaa ctgcctgaat ggtcgcggcc attcgttgac cattacattt
     2701 ccgcaaatac ttatcagatt gatgagacta tagctgttct gaaggaaact gccaaagaaa
     2761 atccttttga tggagtcatt acattctggg atagagatgt ggttccggtg gcggtaactg
     2821 cccgagaact taacttaaag ggcagtccgg tggaagcggc agaacgggct cgaaacaaat
     2881 ggaagatgcg tcaatttttg aaccgcgcac aagttcctca tccaaaatat tgcaaattta
     2941 caaattggac cgaattatat catgcaagca ttgatatgga atacccattg atcgttaaac
     3001 ctgtgggtgc ttctgccagt aaaggcgtat tccgaatatc aaagcctgaa gatttaaatc
     3061 gcgcatatca gcagctgtta aacgccgcgg tgccggaaaa cgataaaatg ttttcttttt
     3121 atcaaaacga gtatattgtt gaagagttta tgaacggaca agaagtcagc attgagggag
     3181 tgatttccga cggagtcatt cactttgcag gtgttactga aaaatggacg gatcagtatt
     3241 tcgaagaata ccagcatgca tttcccgcca ggctgccgga ggctgtggaa cgtgaattat
     3301 tccacatcac cagtgaaggg ataaaagctt tggagctgaa caattgtggt tttcatgccg
     3361 aggtcatgat cacagagaaa gggtgcaaga ttatcgagat caacggtcgt ctgggcggcg
     3421 attttattac tacccatttg gttcctctag ccaaaggtat aaatataacg cgcgcaaacc
     3481 tattggctgt attaggagaa acaataagct ttgaagcttc gaaaagaaga gctgcctgcg
     3541 tcaggttttt aattgcagac cgtgctggtg tgatagaaaa gtgggaaggt gtcgaatcga
     3601 tcaaagaaat gcccggggtc gttgaatttg ttttagaaaa gcagccgggc gatcatgttg
     3661 gcctgccgcc tgaaaagttt catgattccc ggattgctta tgtcatcaca gaagccgaag
     3721 atacagaaaa agcgatcgaa tatgctgaaa atgctttatc tgaagtgagg tgtttcatca
     3781 atggagagga aaagactgtt cctgatcggg attcctgaaa cgcatattga gaaggccgtt
     3841 acgagggcaa aacaacttgg ttttgacgtc ttattaggag atacagaagc ttcattaaaa
     3901 aaatatgagc atttaataaa ggaagctgac caaaaaatcg cattagatta taccaatcat
     3961 gagaatctat tctcagtcgc taaagaaatc catgacaaag agcctttaga tgccatattt
     4021 actttcaaag aagccggctt attcaatgta tccaaacttc agcaggcatt tcatttaaaa
     4081 ggaaatcctc cgtctgtggt gcaagcatgc cttgataaat atacaacgcg ccggctttta
     4141 aaaaaggcag gactaaactc tcccgatttt ggattgtgca ggagcgtgga agacgtatac
     4201 gatttttgga atacatctca acatcctatc attttaaagc cgagatctca gcaaggcagt
     4261 ataggcgtca taaaagttga gaaaaaagag gacattgagg cgtgttttaa agagtgttca
     4321 aaacatgacg aggagaagtc agtattagcc gaagaattta tagaagggca ggaaatttca
     4381 atagaagccg ttgtctgcca aggcaaggtc gacatatttg gtgtgaccga aaagttgcta
     4441 taccccggga cttttgtaga atctgggcat atatcgccgt ataaacataa agaaaaacat
     4501 caggatttgt ataagaatct ggtcaaggaa gttgttcatg ccatggggat cgtatttggc
     4561 cccttgcata ttgaagggta tcacacaaat aaaggatttg tggttggcga ggtacacacc
     4621 cgctatggcg gagacaacat agtgaccatt acagaaatcg ccatgaaatg tgatatgcat
     4681 acacctattt ttgcggaact ggcgggcatc ccatatcaac cggaaaggaa acatgctcaa
     4741 agcgaagtat gcgccgttcg ttttttagaa acgaaccaag gggttgtacg cgcaatcaaa
     4801 gggatcagcg atctcaaaat gatggggaat gtagtagatt ttcatgtaaa ttgcagtgtc
     4861 ggtgatagaa tcagaccgat caaaaacagc tacgatagag caggatggat gattgtaaag
     4921 gggaaaaatg agcgagaagt caatcacgca ttacatgatg cgattgacaa aataaaaata
     4981 atcattaggt gaaggggaga atgatggtga aaaacagaaa atcatcaatt tttagagatg
     5041 ctttaaacag taaaggtttg gtgaaagttg cgggagctca tgacggttta agcgccaaat
     5101 tagcagagaa aaacggattt aatgccgtat gggcaagcgg tttgggaatc tcggctgtgc
     5161 aaactgtacc tgatgccagt atattaacga tgactgaatt tcttgaagcc gccgtcatta
     5221 tgaatgaatc atgcaatttg ccggtcatcg ctgactgtga ttccggctac gggaacattc
     5281 acaatgtcac ccgcatgatc aaaaaatacg aagctgctgg tattgccgga gtttgtattg
     5341 aagataaagt atatccaaaa ttaaactcat ttgacgacag acaacagatc cttgtcagta
     5401 ctgaagaatt ttgcgcaaaa attagagccg caaagatggc tcagcaaaat gacgattttg
     5461 tattgattgc ccgtgtcgaa gctttaattg ctaaattggg tcaagaagaa gcctatacaa
     5521 gagcaaaagc ttatgttcat gctggagcag atgcaatttt aattcattca aaagaacaat
     5581 cgcctgatga aattattgag tttgttaaca attgggacgt ggatgcgccg ttggttgtgg
     5641 ttccgactaa atatccgacg ctctcaatgg aacagcttga gaaattggga gtgaaggttt
     5701 ccatctatgc gaatcaggcg ttgcgcgctt ctgttaaggc tataaatgat acattcgaaa
     5761 gcattataaa taataaatcg tctttgcaga ttgaaaatga catcgtgagc gttaatgaga
     5821 tatttgacat tcaagacgtt ccggggatga agcaactgga gcgtttgatc catagacagc
     5881 cggctaactg aggtttttgt atcgtgctat tttaagaatg gcccataaag acattggagg
     5941 cgtttgaatt gaataaaaga ttatccgata gagtcatgaa tataaaacct tcggccacta
     6001 tgtcattaaa tgccaaaacg aagataatgg taaaagaagg aaaagacatt ataaatatga
     6061 gtgtcggaga accggatctt catccgccat taacagcctc atatgcagga attcaggcaa
     6121 tagtgaaggg gaaaaccggg tatacgccgg cagcagggct gattgaatta agagaatcca
     6181 ttgtgcgata tctgcttaac gaacgaggtt tagaatataa accaaaccaa ataattgcat
     6241 ctgccggggg aaaacagccg ctatataatg tttttcaagc aatttgtgat caagacgacg
     6301 aagttatcct cccttcacct tactgggtat cttatccgga acaaatcaaa ctgtcggggg
     6361 cggttcctgt tattgtaagc tgtgatgaaa ctacaaattt taaaatcaca cccgagaagc
     6421 ttgcagaagt aattacccct aagacaaaag ctgttgttat cacatctccc aataatccga
     6481 cagggtccgt ttattcagaa aatgaactga aagctttagg aaatgtgttg aaagattatt
     6541 ctgaaatttt tatcatttcc gacgaaattt atgatcagtt tgtgtatgag ggcaagcata
     6601 tcagtctgcc gctcattttt cccgaattgc tgaatcggac catcataacg aatggatttt
     6661 ccaaagtctt tgcaatgact ggatggaggc tcggctatat cgcagcccca tcggatatag
     6721 ccgaagccat tgccagcttt caaagccatg ctacaggcag cccgtcaact atttctcaat
     6781 atgccggtat ttctgcttta aacggttttg acaagtcgat ggtcgaagaa tacaaaaaaa
     6841 gacgcgatat attagtcgat ggtttaaatc aaattgaggg cattcaatgc gccaaaccaa
     6901 atggagcctt ttatgcgttt ccgaatgttt cacaattttt cggaacaatg tttgaagatc
     6961 aacaaataat tgatgcggag acattttgtc atcttctgtt ggaaaaacag cacgtgtcag
     7021 ctgttcccgg cacagcattc ggagagccga acaacattcg tttgaatttt gccatcccaa
     7081 aggatcttat cacagaggct ttgaaaagaa ttaataattt tacaactcag ctggcagtta
     7141 aggtataaca gagcgctgaa agcttaaacg agcctcttta tatctgcatc taatgtttag
     7201 gcaggtggtt ttttgaaagg catacgatta agaattcacc ctgtgggctg gaatatcatt
     7261 ttaggcacct tgtttagcag aatgtcagtc tcgatgagca ttcccttcct ttctatttac
     7321 ctaacacaag taaaaggtgt ttctcctgct ttaaccggca tcattgtttc agtaagttcg
     7381 ctggctggga ttgtaatgag cttttacgga gggtatttgt ctgatctttt tggcaggaaa
     7441 attgtgatga taacgtctgt attttgttgg gcgcttgttt ttgtaagttt tatgtttgca
     7501 gatagtgtac tcgcattttt tgtcatcaat gcgcttaacg ggctgtgtca atctatcttt
     7561 gaaccggcgt caagagcatt attatccgat ataagcaaag aagaaaatcg tttgaagatg
     7621 tttaatttgc ggtatactgc gattaatatc ggcgtagttt tcggtcctct tttaggcctt
     7681 agattgggag ctgccaagac ggctctccca tttctgttcg caggttttac atattttctt
     7741 tatggtctat ctctcttatt ttcattccga aaatttaaat tagacgagaa caatcgaaaa
     7801 gaaaataaaa cgactattgc tacggccttt aatgtgacaa ggaaagacaa ggtttttctt
     7861 atcacattac ttggagtgat attatcaata tccggatatg cgcacttttc tacaacattg
     7921 ccccaatatt ttgccgccaa aatagaggac ggggtgacca tattttcatg gcttttagct
     7981 ttgaatgcaa ttgtcgtctt aatcgttcaa taccctattg tgaatatcat gaaaaagttc
     8041 ccgccgattc attcaatcat tctgggaaat gctttaatta gtttcagttt attatttttt
     8101 tcgctatcgt ccaacccatt catatggggc tctatcgtcg tgtttttcac aataggggaa
     8161 gttttgattt tttcgatggt tgatatgctg gtggatgaaa ttgcaaaacc aggcttcaaa
     8221 gggacatact ttggagcagc aggctttaac cgtttaggaa atgtaatcgg tccttggctg
     8281 ggagggattc ttctttcctt ttttggtgta aacgggtcct tctatatgtt tttgatcatt
     8341 tttataacga cagcctcggg aattccggtt ttatttttgg caaaaaaaca tcttgataag
     8401 agcggacatt caaaagttga tgtaacagaa tctcatagga gttaaatgtt ttaacacaat
     8461 gaagaattaa tggcaaagtc tttgaacctc aaaggtttaa aggctttttt cttttcagca
     8521 gcgccccatc agaatgggaa acaagagtgt ttatattttt ggggagagga atacagaatg
     8581 aacggcgaac aaagaaggta ttaatctaag ggactgaccc cataagatga gacaaataaa
     8641 aaacaccttc aagtttgaaa acggatcgtt gttatccgaa attagacttt gaggcgtttt
     8701 tttttcatct ttttgaaacc gttttgcctt gattcatatc taacagcata ggaggtggat
     8761 aaggtgaagg aagaacgatt gatcaaaaag gcgaaaaaag gtgatgccgc agcctttgaa
     8821 aaactgatca cagctcatca ggagacttta tataaaacag cttatctcta tttgcatcac
     8881 aaggaagata cactggacgc tgttcaggaa acggcttaca aggcttttct tcatatcgcg
     8941 caactgaagg agccgaaata ttttaaaacg tggctgatcc ggattttgct tcatacaatt
     9001 tttgcgatga ggaaaaagca cggagacgtc atcccgtttg agccgcagca tgatacgcgc
     9061 gcggagaata agaacattga agaatacata gatcttcgga atgccctgga aacgcttgac
     9121 gaacatatac agctgaccat tcagctttat tattttcaag atttctcgat tgctatgatc
     9181 gctgaacaga ccggtatggc ggaaggcact gtaaaaacgc atctgcacag ggcgagaaaa
     9241 gcattgaagc aggagctgga aaaggaggat aaacatatat ggaaaagcat caaatgaagc
     9301 aattgtatca ggacattgac gtgccgaaag ctgaattgaa aaatgtgata cacagcgccg
     9361 ctgtccgtgt cggaaaagaa ggcgccgtca gacggagatg gggaagaaaa ctgataaacg
     9421 gactcgcggt tgctgctgct ttgtttattc tgtatctgtc ctcaggctta ttcatgccct
     9481 ccgttaatac ggctatggga aacattcctg ttgccggaca aatttacagt ctgtttcagg
     9541 ataaggcagg ttctgcgctg tttaaaagca atttggtgac aaaactgaat gagaaagcgg
     9601 aatcacgcgg aatcacggtg acagtgaaaa gtgtgtatta cgacagcgga cagctcgttt
     9661 acaattttac cgttgacaat ttgaaatcag atgaggagag catctctttt caagttgatt
     9721 ataaagatcc atggaatatg ttagcagagg attatgacaa cagtaatatg aaaaaaatga
     9781 aagacgggca gtacgcggga cagcttcgcc tgttcacgga cggctcaaag ctgaaagacg
     9841 gtgataagct tccgcttgtc attacacaaa tcaaggatat cccgggaaac tggcgcttta
     9901 cactccctat taaaaaacaa aagtccgttt ctcttgaagg aacgaaagct gtgaatgtaa
     9961 atcacggatt ataccgcttt ttcgatatcc gggcggaaaa cggaacgacg ggatcggctc
    10021 tcctgtattc tatcgacttc tatgatgcag ccaaaaatga tgccatctcg atttacgagg
    10081 caacggatga tgccggaaac cattatgaaa tgacggcgtc gaatattgaa cttggcggca
    10141 gaaagaatct tcccggcggc gggaaaagaa tacgcggcca aactcaattc agcaaaccga
    10201 tagacccgaa agcgaaaaca cttttcataa cgggcgatat aaaaacagaa tcagagccgg
    10261 gagaaatcgt gcctctgaaa acaaaactgc ccgtcagtta taaaacgaaa catcatcatg
    10321 tcggcatcac cgtcaaaaag atcaaacagc aaggcagacg ggtgatcgtc gattatcaat
    10381 tcacaggaat taattacagc aaagcggatg aagatcagct gatcaatgtc ggtgagtcaa
    10441 tcggtctcgg caatacgaaa aaaatgaaaa cctggccatc gcttaatgag tatgaaaaag
    10501 gctattatct gaaagggaat aaggcgaaag tcacgaacct taaaacgggt gaaatggaat
    10561 ccgtttttga attggatgat tcatccaata aagactattc gttgcgcgat ttctcattcg
    10621 attcatacgc tttgtacgtc aatcaaacgg ttatgaactt gctggcggat gataagggga
    10681 tcacattcgc ggtgccggtt cggcctgcgg acggaaaatg atgtctggaa ggcggctttt
    10741 gccgtcttcc atttttggtc aattaacgaa taaaccaaat ttttttaacg ggattgttcg
    10801 ttttttttat tgagttttca aaattgaatt gatacaatag actcagaaat caaatatgca
    10861 gatatcgtat aatggcgggg atatggcccg caagtttcta ccaagctacc gtaaatggct
    10921 tgactacgga tcaatctcaa tcgtttgata taaataatcc attcttattt attcagactg
    10981 aacgtatgta gtcaagcgtc ccaaatgtat ttggggcgtt ttttatttgg cggataacgg
    11041 gcagaataaa tgggagagaa tgaaggaggc aattggcttg aagcaatttt ttcagtttga
    11101 tgagctgggg acaagctatc gtaatgaaat catcggcggt ttaacgacct ttttgtcaat
    11161 ggcgtacatt ctgttcgtca atccgctgac attgtcttta aacggtgtga agggatttcc
    11221 ggaagcatta aaaattgatc agggcgcggt gttcaccgct acagccttgg cgtctgcggc
    11281 cggctgtatt ttaatggggc tcattgcaaa gtatccgatc gcgattgcgc cgggtatggg
    11341 attaaatgcg ttttttgctt tctctgtcgt cctcggcatg gggatttcat ggcaggctgc
    11401 gctttccggc gtcttgattt ccggaattat cttcgtggcg ctttcgctga cgggactgcg
    11461 ggaaaaaatc attaatgcga ttccgcctga gctgaaattg gcggtcggcg cgggtatcgg
    11521 tttgtttatc acatttgtcg gtttgcaggg ttcgggcatt attgaagcga actcatcgac
    11581 tttggtgtct atcggcaata ttcacagcgg ccctgtgctg ctgacggttt tcggtgttat
    11641 tgtgacggtc attctgatgg tgcttcgcgt aaacggcggc gtatttatcg gaatgcttct
    11701 gacggcggtt gccggcatgg tctgcggact gattccggtt ccgacgcaca ttgtcggcag
    11761 cgtgccgagt cttgcgccga ctttcggaca ggcgtggatg catcttccgg atatcttctc
    11821 cgtacaaatg ctgattgtca ttttaacttt cttgttcgtc gggtttttcg atacggccgg
    11881 aacgctggtg gctgtagcga cacaggccgg gctgatgaag gaaaacaaac ttccgcgtgc
    11941 gggaagagcg cttctggcag attcgacatc aatcgttatc ggagccgtac tcggtacgtc
    12001 tacaacgact tcttatgttg aatccagctc aggcgttgcg gcgggggcgc gctccggctt
    12061 cgcggctgtt gtgacgggca ttctcttttt gctggcgatg tttttctcgc cgcttctgtc
    12121 agttgtcacc acgaatgtga cggctccg
//
