LOCUS       c00023_gnlPro..        14452 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CGPGODHF_23.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 10:36:30
            Original ID  :: gnl|Prokka|CGPGODHF_23
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 370692
            Orig. end    :: 385144
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14452
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[380692:381523](+)"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..10831
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..14452
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14452
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Putrescine2spermidine"
                     /region_number="2"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             complement(159..932)
                     /locus_tag="ctg23_371"
                     /transl_table=11
                     /translation="LTKQRQDAWSEENDLLLAETVLRHVREGSTQLNAFEEVGDKLNRT
                     SAACGFRWNAVVRHQYEKALQLAKKQRKQRMRALGNGQPAKKKLLYQPPAPDADIMQET
                     AAEETVQTEAPKEDRQAVMSGEHMPYVDESFKEELASLSHLLAPQQPSQKAELTMADVI
                     QFLQSYEGSGKQTSALQMENDRLKRENQELQSKTEQLEAAVEKLEKDQKTIQEDYETLV
                     KIMNRARKLVLFEDDEHASPSFKMDRNGNLEKMAE"
     CDS             1135..1359
                     /locus_tag="ctg23_372"
                     /transl_table=11
                     /translation="MANEFRVCDDCQATNIKTLLPRLKEADPDAKVEVGCQSYCGPGRK
                     KSFAFVNNRPLSAPTEDELIEKVKKKIKK"
     CDS             1519..2820
                     /locus_tag="ctg23_373"
                     /transl_table=11
                     /translation="MAYPNGKLSEEKVFKDPVHRYVHVRDKLIWDLIGTREFQRLRRIK
                     QLGTTYLTFHGAEHSRFNHSLGVYEIVRRMVDDVFKGRPEWDDNERELCLSAALLHDLG
                     HGPFSHSFEKVFHLDHEDYTREIILGDTEVNQVLRKAGPGFPQDVAEVIAKTYKNKQVV
                     SLISSQIDADRMDYLQRDAYYTGVSYGHFDMERILRVMRPREDQIVIKQSGMHAVEDYI
                     MSRYQMYWQVYFHPVTRSAEVILTKILHRAKQLHEEGYIFTHAPVHFYSIFEGKLTLAD
                     YLKLDEAIILYYFQAWEEEEDPILSDLCRRFINRQLFQYAEFNPNEEMSAYFELTALFK
                     EAGIDPNYYLVVDSSSDLPYDFYRPGEEEERLPIHLLTQNGQIKELSRQSAIVESISGK
                     RRTDHKLYYPMDLICDDSENPEAKLKIRQLLGLT"
     CDS             2860..3360
                     /locus_tag="ctg23_374"
                     /transl_table=11
                     /translation="LLKEHAKLMKVFSDSGEIIGRKKLQKIIYIAKKMQYPFYEKYDFH
                     FYGPYSEELTLRIEELCNLGFLDEVKEKKGGYFQYRYSLTETGAEFLHHAELTMPDMKK
                     YIDSVNSRSSRFLELVSTILYFDGLEAEEKKEKVFTIKSKQKYTDEEYDEALHYIEELK
                     HIC"
     CDS             complement(3425..5002)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_permease_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_375"
                     /sec_met_domain="AA_permease_2 (E-value: 5.4e-63, bitscore:
                     207.8, seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQVKSLRVTAFDGKDNLIGCGRQYDWKRNGTDGETEHRIVDYTE
                     CDTGKSQRVPLGFCFWMEGCVLRNILQKKDITQLLEQSRNRQTAKTMGGFDLTLLGIGA
                     VIGTGVMVLTGITAAKNAGPSVIFSFIIAAVVCSLAALCYAEIASVLPVYGSAYIYSYT
                     TMGEIVGHLMGWTLLSVYMVTASAVASGWSSYFNNLLAEIGMPLPDSLLHVPSQGGIVN
                     LPAIIITLLIAVVLSRGSKESKTFNNVMVLVKIGIVLLFIITGSFFVKPGNWHPFMPFG
                     IKGVITGASAVFFAFLGFDAISASAEEVKKPQRNLPIGIIGSLVICTLVYVIVCLVMTG
                     MVPYSQLNVPEAMSYVLQTVGQNAVAGVIAAGAVIGLMAVVLAHTYAATRISFAMARDG
                     MLPKVFTIVGKKSGAPIFNTWLIGLISACIAGFVDLKELSDLSNIGALLTFAMVSLSVL
                     ILRRTHKDLPRGFKVPFVPVLPILAIICCLFLMVNLPLKTWLYFAVWLIIGVIVYFLYS
                     YKHSKLRQ"
     CDS             5188..5607
                     /locus_tag="ctg23_376"
                     /transl_table=11
                     /translation="MEHDILQANVLDYALTKYLKSTKKLDEATIPKSINNIRGFILRII
                     YRHGTCTIKDILQEVTLSPSATTTALNHLEKEGFVERSRNNEDRRTVWMTLSESGKMAA
                     MQMIENRQMLIDELFEKLTEEEKNTFFSLVEKVMK"
     CDS             complement(5645..5833)
                     /locus_tag="ctg23_377"
                     /transl_table=11
                     /translation="MPLVTVKMLEGRTDEQKRNLVEKVTEAVKETTGAAEEKIIVMIEE
                     MRKDHYAVAGKRISDTE"
     CDS             5939..6598
                     /locus_tag="ctg23_378"
                     /transl_table=11
                     /translation="LDRFLYYPLELMPYVVITLIVAFTMHELAHAYVAYRFGDDTAARQ
                     GRLTLNPIKHLDVFGTILILVAGFGWARPVPVNRRAFKRPRLAGVLVSVAGPVSNLLLA
                     FIGFFLLVLMHAYGMELLSAFSMGLDRFFSIWIQLNLALCLFNLLPLPPLDGYRIIEDL
                     VPPRVRAKMTQFESYGIIVFLVLFVTPVGSYVVWPLLSEGRDWILKVFAIIFQPLL"
     CDS             6611..7129
                     /locus_tag="ctg23_379"
                     /transl_table=11
                     /translation="MEEKKKKTIGFNIIKSDPTDGHGGFGAGALSLDNISPVFVDVEEK
                     EAFVDIGAMHARSVVEKGIKFLPNKDEVPNGKPYWLVWVTIDRKEEGPYYAGVTACEMT
                     VDRSIRRGYKSLPEHVNLMDKSMKRCIVVDKMDASSKQVLAEFLQKHDQGLWERSSDEL
                     KTGLLPEEK"
     CDS             7273..7704
                     /locus_tag="ctg23_380"
                     /transl_table=11
                     /translation="MFTVFEIGPWVIEADAEETRKQYEKSWPDPCDCGHCRNFSEAVNL
                     LPAEKTRLFTQFGIRPAVCHDLGEHGKENGLHHYAGSYPIVGRLREGWPKFHIERTGDI
                     RFSFSLPSTTFFIPKGFPDPIIHLDFSLLLPWVLEEDAD"
     CDS             complement(7729..9801)
                     /locus_tag="ctg23_381"
                     /transl_table=11
                     /translation="VDKVSGKQLRITFKIIRACIFLTLIGGMLAGVCFTSVLLAAKWQG
                     APSVRVPQSTILYANDGSKLGETDFGEKRYWVRLKDINPIAVQAAIAVEDQNFYNHHGF
                     DYRRMAAAALADIKAMAKVQGASTITQQYARNLYLEHDKTWKRKWNEAFYTIRLEQNYS
                     KNEILEGYVNTIYYGHGAYGIEAASRLYFGKHAKDLNDAEAVLLAGIPKGPSGYSPYVS
                     EKKAKQRQETILRLMIGQKMISKEKAERLKKTPLAYQPLKNRTAAKTAPYFYDDAMKEL
                     GKKLGMTREQLATSGLRVYTTLDKRMQRIAENTVAHTIRTGSDIQVGFSAIDPATGRVL
                     ALLGGRDYEKSPFDRATQAKRQPASTIKPLLYYKAIQSGFTPVTLMKSEATEFQIDDNG
                     DTYSPSNYNGYYANKPITLLQALALSDNIYAVKTHLFLGMNKLVSAAKEFGISEHLKPL
                     PSLALGTEPVRPIEMVNAYAMLANGGKQITPSFITKVTDTAGNVLYEQPRGHQQTLDKK
                     AAFVTASMMTGMFDQDLNGYTSVTGRTISDRLTRTYGGKSGTTSADSWMIGFNPALAAG
                     VWTGYDKSSTIDSVEEKSYAKTIWADFMEKALEGEPEIALKPPKGVTGVYIDPASGYTS
                     GPGCAAKHYTYFIAGTEPADVCYGPEPSKKEKEHVPARKEAPRKKWWDKWLGKKD"
     CDS             10001..10831
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_382"
                     /sec_met_domain="Spermine_synth (E-value: 4.4e-72,
                     bitscore: 236.0, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 4.4e-23,
                     bitscore: 75.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LSELWYTEKQTKNFGITLKVKQTLHTEQTEFQHLEMVETEEFGNM
                     LFLDGMVMTSEKDEFVYHEMVAHVPLFTHPNPENVLVVGGGDGGVIREILKHPSVKKAT
                     LVDIDGKVIEYSKKFLPSIAGKLDDPRVDVRVDDGFMHIAKSENEYDVIMVDSTEPVGP
                     AVNLFSKGFYAGISKALKEDGIFVAQTDNPWFTPELITNVQRDVKEIFPITRLYTANIP
                     TYPSGLWTFTIGSKKYDPLEVEDSRFFDIDTKYYTKELHKAAFVLPKFVSDLIK"
     CDS             10890..11762
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Arginase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_383"
                     /sec_met_domain="Arginase (E-value: 6.9e-82, bitscore:
                     269.6, seeds: 235, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFDEAYSGKVFIASRPDWKEADAILYGMPMDWTVSYRPGSRFGP
                     GRIREVSIGLEEYSPYLDRDLADLNFFDAGDIPLPFGNPQRSLDMIEEYVDSILEKGKF
                     PLGMGGEHLVSWPVIKAMYKKFPDLAIIHFDAHTDLRTDYEGEPLSHSTPIRKAAELIG
                     PQNVFSFGIRSGMKEEFEWAKENGMHISKFEVLEPLKKVLPQLAGRPVYVTIDIDVLDP
                     AHAPGTGTVDAGGITSKELLASIHEIARSEVNVKGADLVEVAPVYDHSEQTANTASKMI
                     REMLLGFVK"
     CDS             11917..12135
                     /locus_tag="ctg23_384"
                     /transl_table=11
                     /translation="MKTAVENELELKKIEISVIKLIIAEKPNKEIAKSLNYSQRNVEYI
                     IAGLCKKWNVSTRVGIVSEAYKRNCIQ"
     CDS             complement(12182..12721)
                     /locus_tag="ctg23_385"
                     /transl_table=11
                     /translation="MQIELSSFKERKINFLSSFLFYIIGLAFYLSSLLPFMKSLIPKNI
                     SIQVIDHIKHLDYIIAIVALFLLMFGVIFEGFVLFLIINFLGAQIKIKTFYSLFMFSNI
                     PVAIKFFLISFKNIFAEHPNTSLFFTSNHLIFSIFDLFNITYLFLLFILLKWRTNLNYL
                     TISVFIFTAFLYRMFF"
     CDS             complement(12726..13223)
                     /locus_tag="ctg23_386"
                     /transl_table=11
                     /translation="LFKKNVLVKLYILCLILFLIALFTAYFYTDPASNVNNLNRNIRPD
                     FFQIFFNNIKVASLLVFLGPLTLSLGTVAVLIINGLILGNAIGNIKDNLNLLLLVIPHG
                     IIEVPVLLLAASVGMKLTLDLLLLKINLKFTFKYIGIIFIGLIIAAMLETFITPIFIKG
                     VS"
     CDS             complement(13282..13716)
                     /locus_tag="ctg23_387"
                     /transl_table=11
                     /translation="MVRLSLYEISQQILLRISPLNYNFSEIRNSNSFQYILLFNLLGIL
                     KKLEEKMNLLLKSQNSKAIFTLVASGIIVLALFSMKHNHLSMDVIDILNRAGIIAPSWL
                     VSAITATGSVLAIITVLGSLGAGLPLAVLEQLAGASTAAA"
     CDS             complement(13750..13935)
                     /locus_tag="ctg23_388"
                     /transl_table=11
                     /translation="MYEYKFIKVEVNRWKGKPKEDYKEIIEKYSQQGWKLVQIFAPPIS
                     GYGAADYFDIIFEKKV"
     CDS             complement(13970..14173)
                     /locus_tag="ctg23_389"
                     /transl_table=11
                     /translation="MKKMDEMQKHQSGIAARIAFSFYTVALLIWSLIDYFKNGNTGWQF
                     PILLIGCALYLWIQVYHNRKTR"
     CDS             complement(14187..14390)
                     /locus_tag="ctg23_390"
                     /transl_table=11
                     /translation="VDNNIKKLRTAADISQNDLAKLCNVTRQTINAIENNKYDPTLGLA
                     FSIAHALNTGIDKVFNYNAKKN"
ORIGIN
        1 ttgaatcttt atgcttatgt gcgggcgggg accgagatgc gcagcccttg cggaaagaag
       61 gcctcctgaa caatgtttac attaatatag atcaggattc gcgtcattga caaatggcaa
      121 aaaccccttt ttccatgaca aggaaagggg tttttccgtt attcggccat tttttctaaa
      181 ttgccgttcc ggtccatttt aaaggacgga gaggcatgtt catcgtcttc aaataaaact
      241 agttttctgg ctctgttcat aattttcacc aaggtttcgt agtcttcctg aatggttttt
      301 tgatcttttt caagcttttc gacggccgct tccagctgct cggttttaga ctgaagttct
      361 tggttttccc gttttaaacg gtcattttcc atttgcaggg cggaagtttg ctttccgctg
      421 ccttcatagc tctgcagaaa ttgaatgacg tctgccattg tgagctccgc cttttggctc
      481 ggctgctgag gcgccagcaa atgtgataaa ctagctaact cttccttgaa gctttcatcg
      541 acataaggca tatgttcgcc ggacatgacg gcttgccgat cctcttttgg cgcttccgtt
      601 tgaaccgtct cttcggctgc ggtttcctgc atgatgtccg catccggtgc aggcggctgg
      661 tataatagtt tcttcttggc gggctggccg tttccgagcg cgcgcatccg ctgtttccgc
      721 tgttttttgg caagctgaag cgctttttca tattgatggc ggacgacggc attccacctg
      781 aatccgcacg ctgccgacgt tctgtttaat ttatcgccta cctcttcaaa ggcgttcagc
      841 tgcgtgcttc cttcccgaac gtgacggagc acggtttccg caagcagcag gtcattttcc
      901 tccgaccagg cgtcctgtct ttgttttgtc aatgttctca acccccaata tctttgatgg
      961 tattagaatg tccagattgg aaaatattta tacaaattgg ctgaaagaat gagagatacg
     1021 cagagccttg caggataaga tgaatccttg tacaatgaga tgtgatgtga tttttttcgt
     1081 ttttaaaatt aagatttaac atagaggaac attgaatgaa gggaagcgta catcatggct
     1141 aatgaattcc gagtgtgtga tgattgccag gccaccaata ttaagacttt gctgccgcgt
     1201 ttgaaagaag ctgacccgga tgcaaaagtg gaggtcggat gtcagtcata ttgcgggccc
     1261 ggacgcaaaa aatcgtttgc tttcgtaaac aaccgcccgc tgtcggcgcc gactgaggac
     1321 gagctgattg agaaagtgaa aaagaagatc aaaaagtaaa tgtgtatttt acgacagcct
     1381 cgcccgatgg gtcaggcttt tttgcttcaa aaaatcaatg acggaaaact ggaacaaaac
     1441 gccggacaaa ttcaaggatg ttttcaaatt acagagccga tataatagaa tcacggctaa
     1501 aaaaaagagg gaatgacgat ggcgtatcca aacggaaaat tatcagaaga aaaagtgttt
     1561 aaagatcccg ttcaccgcta tgttcatgtg cgggacaagc tgatctggga tttgatcggc
     1621 acccgtgaat ttcagcggct gcgccggatc aaacagctcg gtacgacgta tttgacgttt
     1681 cacggcgcgg aacacagccg ttttaaccat tctctcggcg tctatgagat tgtcagacga
     1741 atggttgatg atgtttttaa agggcgtcct gaatgggatg acaatgaacg cgaactctgt
     1801 ctcagcgccg cgcttttgca cgatttggga catgggccgt tttcgcattc ctttgaaaag
     1861 gtttttcatc tggatcatga agactatacg agggaaatca ttctcggcga caccgaggtg
     1921 aatcaggttc tcagaaaggc gggaccggga tttccgcagg atgttgccga agtcattgcc
     1981 aaaacataca aaaacaagca ggtggtcagc ctgatttcga gccagattga cgccgacagg
     2041 atggattacc ttcagcggga cgcatactat acgggcgtca gctacggaca ttttgatatg
     2101 gaacggattt taagggtgat gcgtccgcga gaggaccaga tcgtcattaa gcaaagcggc
     2161 atgcacgccg tcgaagacta tattatgagc cgctatcaaa tgtactggca ggtgtatttt
     2221 catcccgtga cgagaagcgc tgaagtcatt ttgacgaaaa ttctccaccg tgcgaagcag
     2281 ctccatgaag aagggtatat attcacgcat gctcccgttc atttttattc catttttgaa
     2341 gggaagctga cgcttgcgga ttatctgaag cttgatgaag ccatcatttt atattatttc
     2401 caggcttggg aggaagaaga ggacccgatt ctgtccgact tgtgccgccg cttcattaac
     2461 cgccagctgt ttcaatatgc cgaatttaac cccaatgagg aaatgtcggc ttattttgaa
     2521 ctgaccgctc tgtttaaaga ggcgggaatt gatcccaatt attatttagt ggtcgattct
     2581 tcatcggatc tgccgtatga tttttaccgg ccgggtgaag aggaggagcg tctgccgatt
     2641 cacttgttaa cgcagaacgg ccagatcaaa gagctgtcca ggcagtccgc cattgtcgaa
     2701 tccatttcgg gcaaacgccg gacggaccat aagctctact atccgatgga cctcatttgc
     2761 gacgattcag aaaaccctga agcaaaatta aaaatccggc agctgctggg actgacatag
     2821 aaggattttg gtaaagaagg aaaaggagat gtcgggaatt tgttgaaaga acatgcaaaa
     2881 ctgatgaagg tgttctcgga ttctggagaa atcatcgggc ggaaaaagct gcagaaaatc
     2941 atttatatcg cgaagaaaat gcagtatcct ttctacgaaa aatatgattt tcatttttac
     3001 ggcccgtatt ccgaagaact gacgcttcga attgaagagc tgtgcaatct tgggtttctg
     3061 gatgaggtga aggaaaaaaa gggcggctac tttcaatacc ggtactcgct gacggagacg
     3121 ggagccgagt ttttacatca tgcggagctt acgatgccgg atatgaagaa gtacatcgac
     3181 agcgtcaaca gccgctcatc ccggtttctg gagctggtgt ctacgatttt gtattttgac
     3241 ggtcttgaag ctgaggaaaa gaaagagaaa gtgtttacga taaaaagcaa acagaaatat
     3301 acggatgaag aatatgatga ggcgcttcac tacatagaag agctgaaaca catttgttaa
     3361 aggcgatggc tttcgtcttt tttgatgaaa aaaccaggcc gcgataaagc gggcctggtt
     3421 ttgtttattg tctcaatttg ctgtgcttgt acgaatataa aaagtaaacg atgacgccga
     3481 tgatcagcca gacggcaaaa taaagccacg ttttcagcgg cagattgacc attaaaaaca
     3541 aacagcagat aatggccaaa atcggcagta cgggtacaaa aggcacttta aatccccgcg
     3601 gcagatcctt atgggtgcgg cgcagaatca gcacggacag actgaccatg gcaaatgtca
     3661 atagcgcgcc gatgtttgag agatccgaca gctctttcag atcaacaaaa cccgcgatgc
     3721 aggcgctgat cagtccgatc agccacgtat taaagatcgg cgctcccgat ttctttccga
     3781 caatggtaaa gactttcggc agcattccgt ctcttgccat cgcaaaagat atacgggtcg
     3841 ccgcataggt atgggcgaga acgacggcca tcagtccgat caccgcaccg gcagcgataa
     3901 cgcccgccac cgcgttttgt ccgacagtct gtaacacata agacatggct tccggcacat
     3961 taagctgtga atacggaacc atacccgtca tgacgagaca gacgatgacg tataccaatg
     4021 tacagatcac cagggaaccg ataataccga tcggcaggtt gcgctgcggt tttttgactt
     4081 cttcagccga agcggaaatc gcgtcaaacc cgagaaacgc aaaaaagacg gcagaagccc
     4141 ctgtaatcac gcctttgatt ccaaaaggca taaaaggatg ccaattgccc ggctttacaa
     4201 aaaagcttcc tgtgatgata aacagcaaaa caattccgat ttttacgaga accattacat
     4261 tattaaaggt tttgctctcc ttggagccgc gtgacagaac gacggcaatt aatagagtaa
     4321 tgatgatggc aggaaggttg acgatgcccc cctggctcgg cacgtgcagc agactgtccg
     4381 gcaaaggcat gccgatttcg gctaacagat tattaaaata acttgaccag ccgcttgcca
     4441 ccgccgacgc cgtcaccata taaacggata agagcgtcca gcccattaaa tggccgacaa
     4501 tttctcccat ggtggtataa gagtaaatat aggcgcttcc gtaaaccggg agaacagaag
     4561 cgatttcggc gtaacataat gctgcaaggc tgcagacaac ggctgcaatg ataaaagaaa
     4621 agattacgga aggtccggcg tttttcgcgg ccgtaatgcc tgtaagaacc atgacgcccg
     4681 tcccgatgac ggcgccgatg cccagtaatg ttaaatcaaa tccacccatc gttttggcag
     4741 tctgcctgtt tctgctttgt tcaagcagct gggtgatgtc ttttttttgt aggatattcc
     4801 gcaacacgca tccctccatc caaaagcaaa agccaagagg gactctttgg cttttacccg
     4861 tgtcacattc tgtgtaatcg acaatcctgt gttctgtttc cccgtctgtt ccgtttcttt
     4921 tccagtcata ttgtctgccg catccgatca gattatcctt tccgtcaaac gcagtcaccc
     4981 ttaatgattt tacctgaatc atgtctataa aaccagcatt gcataaaagg gatgggtgaa
     5041 aaagtaggag ataatagtct gtatagggca ggataaaagt tgcgggcttt ccggccgaaa
     5101 ttttgacttt ccccgcgagg tatcagtaaa atgtaataaa aaacaatcaa atgatgatgg
     5161 atgcatcttg aaatggggag tttctgcatg gagcacgata tattgcaagc aaatgtactg
     5221 gattacgcgc tcacgaaata tttaaagagc acgaaaaagc ttgatgaggc gacaattccg
     5281 aagagtataa acaatatcag aggatttatt ctcaggatta tttaccggca cggcacgtgc
     5341 acgattaaag atatattgca ggaagtcaca ttatcgcctt cagccacgac aaccgctctg
     5401 aatcatttag aaaaagaagg tttcgtggaa aggtcgagaa ataacgaaga ccggcgcacg
     5461 gtatggatga cgctttccga atcgggaaaa atggcggcca tgcaaatgat tgaaaaccgg
     5521 cagatgctca ttgacgagct gtttgaaaaa ttgacagagg aagaaaagaa tacctttttc
     5581 agcctcgttg aaaaagtaat gaaataagcc ggcctgacat agcagcgccg gccgttatca
     5641 aggattactc cgtatcgctg atccgtttgc cggcgacggc gtaatgatcc tttctcattt
     5701 cttcaatcat gacaatgatc ttttcttcgg ctgcgcctgt cgtttctttt acggcttctg
     5761 tcactttttc aaccagattc cgtttttgtt catctgtgcg gccttcaagc attttaacgg
     5821 ttacgagcgg catggtgctg atcctccttt atcgtttcct ctctttggaa gagaggtcac
     5881 ttatagtata ctgaatgaag gacaatcttg cattttttaa aaaaggggat ttttacattt
     5941 ggacagattt ttatattatc cgctggagct tatgccctat gtcgtgatta cgctgatcgt
     6001 ggcatttacg atgcatgaac tggcgcacgc atatgtcgcg tatcggttcg gagacgatac
     6061 cgcggcgaga cagggcagat taacgctcaa tccgattaaa catcttgatg ttttcggaac
     6121 gattctaatt ttggtcgctg gtttcggctg ggcccgtccg gtgccggtga accgccgcgc
     6181 ctttaaaaga ccgcggctgg cgggagtgct ggtttccgtc gccgggcctg taagcaacct
     6241 gcttcttgcc tttatcggtt tctttttgct agtgttgatg catgcttacg gaatggagct
     6301 gctttctgca ttcagcatgg ggcttgaccg ctttttctct atttggattc agctgaatct
     6361 cgcgctgtgt ttattcaacc tgctgccgct tcctccgctt gacggctacc ggattattga
     6421 ggatctcgtg ccgccgcggg tgcgcgccaa aatgactcag tttgagagct acgggattat
     6481 cgtgtttctc gtgctgtttg tgacaccggt cggctcctat gtcgtgtggc cgctgttaag
     6541 cgaggggaga gactggattc tcaaggtatt tgccattata tttcaaccgc ttttgtagga
     6601 gggtattttc atggaagaaa aaaagaagaa aacaatcgga ttcaatatta ttaaaagtga
     6661 tccgaccgac ggacatggcg gttttggcgc cggggcgctg agccttgaca atatttctcc
     6721 ggtatttgtc gatgtggaag agaaggaagc cttcgttgac atcggcgcaa tgcatgcccg
     6781 cagtgtcgtt gaaaaaggca tcaaattcct gccgaacaaa gatgaagtgc cgaacggaaa
     6841 accgtactgg ctcgtgtggg tcaccatcga cagaaaagaa gaaggccctt attacgcggg
     6901 tgtgacggct tgtgaaatga ccgtggacag aagtatccgc agaggctata agtcattgcc
     6961 ggagcatgtg aatttaatgg ataaatcaat gaagcgctgc attgtcgtgg ataaaatgga
     7021 cgccagctca aagcaggtgc ttgctgaatt tctgcagaag catgaccaag ggctctggga
     7081 acgttcatcc gatgaattga aaacaggtct gcttccggaa gaaaaataat ttgtgaactt
     7141 tttgtgaact ttataaatat ttgcactatt ttacatttgt actgagtaaa ctgttgatac
     7201 agaatcagga catggaaagt cccgagccga accaagactc ggggtttttc atgtttacgc
     7261 ggaggtttca tcatgttcac cgtctttgaa atcgggcctt gggtcattga agcagatgcg
     7321 gaggaaacga gaaaacaata cgaaaaatca tggcctgatc cttgcgattg cgggcactgc
     7381 cggaactttt ccgaggcggt gaatctcctt cccgccgaga aaacaagatt gtttacgcag
     7441 tttgggattc gtccggctgt ctgtcacgat ttgggggagc atggaaagga aaacggcctg
     7501 catcattatg cgggcagcta tccgattgtc ggcaggctta gggaaggctg gccgaagttt
     7561 catatcgaga ggacgggaga tatccgcttt tcgttttcat tgccgagtac aacatttttt
     7621 ataccgaagg gttttcctga ccctattatc catctcgact tttcactctt gctcccatgg
     7681 gtgcttgagg aagacgcgga ttaaagcccg gcgcgcaatg caccgggctc agtctttttt
     7741 gccgagccac ttatcccacc attttttgcg cggagcttct ttgcgggcgg gtacgtgttc
     7801 cttttctttt ttagacggtt ccggtccgta gcatacatcc gcgggctcag tgcctgcgat
     7861 gaaatacgta taatgctttg cggcgcagcc gggtcccgaa gtgtagccgg aagcgggatc
     7921 gatatagacg cccgtgacgc ccttcggcgg tttaagcgct atttccggtt ctccttcgag
     7981 cgccttctcc ataaagtccg cccaaatcgt cttcgcatag cttttttctt ctactgaatc
     8041 aatcgtgctg cttttgtcat agcctgtcca tacaccggcg gcaagagccg ggttaaagcc
     8101 gatcatccag ctgtctgcgc tcgtcgtgcc tgatttaccg ccataggttc gggtcagccg
     8161 gtcagaaatg gtgcgtcccg tgacggaagt atagccgttt aaatcctgat caaacatgcc
     8221 cgtcatcatg ctcgccgtca caaaagcggc ttttttatca agcgtctgct gatgtccgcg
     8281 cggctgttca tacaagacat tgccggcggt atccgtcact tttgtgataa aggaaggggt
     8341 gatttgtttt cccccgtttg cgagcatcgc gtaggcatta accatctcaa tcgggcgcac
     8401 gggttcagtt ccgagcgcca gagacggaag gggctttaaa tgttcgctga tgccgaattc
     8461 ctttgccgcc gacacgagct tattcatgcc gagaaagaga tgggtcttca cggcataaat
     8521 gttgtctgat aacgcaagcg cctgaagcag cgtaatcggt ttattggcgt agtagccgtt
     8581 gtaattgctt ggagaataag tatctccgtt gtcgtcaatc tggaactctg tggcttcgct
     8641 tttcatcagc gtgaccggtg taaagccgct ttgaatcgct ttgtagtaca aaagcggctt
     8701 gatcgtggaa gcaggctgcc gtttcgcctg tgtcgcccgg tcaaacgggc ttttttcgta
     8761 gtcacgtccg ccgagaagcg caagcacgcg tcctgttgcc ggatcaatcg cggaaaagcc
     8821 gacctgaatg tcagagccgg tacggatcgt atgtgccaca gtgttttccg caatccgctg
     8881 catgcgctta tcaagcgtcg tataaacacg caatccgctc gttgccagct gttcgcgcgt
     8941 catgccgagc tttttcccga gttctttcat cgcatcatcg taaaaataag gcgccgtttt
     9001 cgccgcggtt ctgtttttca gcggctgata ggcaagcggc gttttcttaa gcctttccgc
     9061 cttttctttt gagatcattt tttggccgat catcagtcgg agaatggttt cctggcgctg
     9121 tttggccttc ttttcgctga catatggcga atagccggac gggcctttcg gtatgcccgc
     9181 caaaagcacg gcttccgcat cgttcagatc tttggcgtgt ttgccgaaat acaggcgcga
     9241 ggcggcttca attccgtatg caccgtggcc gtaatatatc gtatttacat aaccttctaa
     9301 aatctcgttt ttagaatagt tctgttcaag gcggatcgtg taaaatgctt cgttccattt
     9361 tcgtttccat gtcttatcat gctcaaggta gagatttctc gcgtattgct gggtgatggt
     9421 gcttgcgccc tgaaccttgg ccattgcctt tatgtcagcc agcgcggcgg cggccatccg
     9481 ccggtaatca aaaccgtgat gattgtaaaa gttttgatcc tccaccgcaa tggcggcctg
     9541 caccgctatc ggattgatat cttttaaccg gacccagtag cgcttttccc cgaaatcggt
     9601 ctcacctagc tttgagccgt catttgcata aagaatcgta gactgaggaa cccggacgga
     9661 gggggcgccc tgccatttcg ctgcaagaag aacggatgtg aagcagacgc cggccagcat
     9721 tccgccgatc agtgtcagaa agatgcaggc gcggatgatt ttgaacgtga ttctgagctg
     9781 ttttccagat actttatcca cttttgggaa cccccttttt catgattcta ttattatgtg
     9841 aaaaaagggg gttttttaaa catatcaaac cggacacttc tttacttttt cccctccatc
     9901 ctctatactt tttccttagg tgaaaatgag attttaaccg gaataaaagc gatacagacg
     9961 cttacaataa atgaaataag ccttgaaagg gagatgacaa ttgagcgagc tttggtatac
    10021 ggagaagcag acgaagaatt tcggcattac attaaaggtg aaacaaacat tacatacgga
    10081 acagacggaa tttcagcatc tggaaatggt ggagacagaa gaattcggca acatgctgtt
    10141 tttagacgga atggtcatga cttctgaaaa agacgaattc gtctatcatg aaatggttgc
    10201 gcacgtcccg ttatttacgc acccgaatcc ggaaaacgtc ctcgttgtcg gcggcggaga
    10261 cggcggtgtc atcagagaga ttctgaagca cccaagcgta aaaaaagcga cgcttgtcga
    10321 cattgacggc aaggttattg aatactctaa aaaattcctt ccgtccattg cgggcaagct
    10381 tgatgatccg cgcgtcgacg tgagagtcga tgacggtttc atgcacatcg cgaaatcaga
    10441 gaatgagtat gacgtcatca tggttgattc aacagaaccg gtcggaccgg ccgtcaatct
    10501 gttctcaaaa ggcttctatg ccggaatttc caaggcgtta aaagaagacg gcatcttcgt
    10561 cgcgcagacg gacaacccgt ggtttacacc ggagctgatt acaaacgtac agcgtgacgt
    10621 gaaagaaatc ttcccgatca cccgtctgta tacggctaat atcccgacgt acccgagcgg
    10681 cctgtggaca tttacaatcg gttctaaaaa gtacgatccg cttgaagtgg aggacagccg
    10741 tttctttgac atcgacacga aatattacac aaaagagctt cacaaagcgg catttgttct
    10801 tccgaaattt gtgagcgact taatcaaata aaaacgtacg gcgcaggagc gaatcttgcg
    10861 cttttttaca ggaaagcgag ggttttatca tgaggtttga tgaagcatat tcaggaaaag
    10921 tatttatcgc aagccgcccc gactggaaag aggcggacgc catcctttac ggcatgccga
    10981 tggattggac ggtcagctac cgtccgggtt cgcgtttcgg cccggggaga atccgcgagg
    11041 tgtcaatcgg tcttgaagaa tacagcccgt atctcgaccg tgacttggct gatttgaatt
    11101 tctttgatgc cggcgacatt ccgcttccgt tcggcaatcc gcaaagaagc cttgatatga
    11161 ttgaagaata cgtggacagc attttagaaa aaggaaagtt cccgctcggc atgggagggg
    11221 agcaccttgt atcatggcct gtcataaaag ccatgtataa gaaatttccg gaccttgcca
    11281 tcattcattt tgacgcgcac accgacctgc gcacggatta tgaaggcgaa ccgctttccc
    11341 actctactcc gatccgcaaa gcggccgagc tcatcgggcc gcaaaacgta ttttcattcg
    11401 gcatccgttc cggaatgaag gaagaatttg aatgggcgaa agaaaacggc atgcacattt
    11461 ctaagtttga agtgcttgag ccgctgaaaa aagtgctgcc gcagcttgcg ggacgccctg
    11521 tttatgtcac catcgatatc gacgtgcttg atcccgctca tgcgccggga acgggcacgg
    11581 ttgacgcagg aggcatcacg tctaaagaat tgctcgcgtc catccatgaa atcgcacgct
    11641 cagaagtcaa cgtaaaaggc gccgacctcg tagaagtggc accggtctat gatcactcag
    11701 aacaaaccgc aaacacggca agcaagatga ttcgtgaaat gctgcttggg tttgtgaaat
    11761 aaaagaattt cccccgcttg aaacacgcgg gggcttttta tattgtatat aaactactta
    11821 gaagttagtt attttaccat taataattga tgttattgat aaaaattata taatagggta
    11881 ttatttagta aatacatctt tagaaaggaa gttagaatga aaacagcagt agaaaatgaa
    11941 ttggaattaa aaaagattga aatttcagta attaaactga taattgctga aaaacctaat
    12001 aaagagatcg ctaagtcatt aaactactcg cagcgtaatg tcgaatatat catagccggt
    12061 ctctgtaaaa agtggaatgt gagtactaga gtcggtattg tttcggaagc atataaaagg
    12121 aattgtatac agtgaacgat atgaaagaaa aacccctatt gagggggttt atttatatat
    12181 gctaaaaaaa cattctatac aggaatgccg taaaaataaa aactgagatt gtcaggtagt
    12241 tcaaattcgt tctccatttc agaagaataa acaaaagaaa taagtatgta atattgaaca
    12301 aatcaaagat agaaaaaatc aaatgattac ttgtgaaaaa taaactagtg tttggatgtt
    12361 ctgcgaaaat gtttttgaat gatataagaa aaaacttaat tgcgaccggg atgttagaaa
    12421 acataaatag ggaataaaaa gttttgatct taatttgagc gccaagaaaa tttataatga
    12481 gaaataatac gaatccttca aaaatcaccc cgaacattaa aagaaacaga gcaacaattg
    12541 ctatgatata atctaaatgt tttatgtgat caataacttg tatagatatg tttttgggaa
    12601 ttaaactttt cataaaaggt aaaagggaac ttaaataaaa ggctaacccg ataatataaa
    12661 acaaaaacga ggacaaaaaa ttaatttttc gttccttaaa tgaagataat tcaatttgca
    12721 taatcctaag agactccttt tataaagata ggtgtaataa atgtttctaa catagctgct
    12781 attattaaac cgataaatat aataccaata tatttaaaag tgaatttcaa atttattttg
    12841 aggagtaata aatctaaagt taatttcatt cctacagagg ctgcaagaag caataccggc
    12901 acttcaatta ttccatgggg aataacaagc agtaaaaggt ttaaattgtc tttgatgttt
    12961 cctatcgcat tccctaaaat taatccattt ataattaaaa cagcaaccgt gccaagtgac
    13021 agcgtcaacg gtcctaaaaa aacaagcaga ctcgctactt taatattatt aaagaaaatc
    13081 tgaaaaaaat ccggacggat atttcgattt agattattta catttgaagc gggatctgta
    13141 taaaaatatg ctgtaaataa agcaattaaa aataagatca gacagagtat gtacaatttg
    13201 actaaaacat tctttttaaa caatgtattt tcatccattc gttaaaggga ctgccaggga
    13261 tattgaattt aatgttttat attatgctgc tgctgtactt gctccagcca attgttctaa
    13321 aacggccaat ggcaagcccg caccaagaga tcctaaaaca gtaatgatag ccagaactga
    13381 acccgttgcg gtgatagcac tgacaagcca actaggagcg ataattccag ctctgtttaa
    13441 aatatcgata acatccatgc ttaaatgatt atgtttcata ctgaaaagtg cgagaacaat
    13501 gattcctgat gctactaatg taaaaattgc tttactattt tgtgatttta aaagtagatt
    13561 cattttttcc tccaattttt tcaatatccc cagcaagtta aataataaaa tatattggaa
    13621 gctatttgaa ttgcggattt ccgaaaaatt atagttaaga ggtgaaatcc gtaaaagtat
    13681 ctgctgactt atttcgtaca aagaaagccg gaccatatgt atgatccggc tttcttcggt
    13741 actgaaacat tatacttttt tttcaaaaat aatatcaaaa taatcggctg ccccatagcc
    13801 tgaaatagga ggagcaaata tttggaccag cttccatcct tgctgcgaat acttttcaat
    13861 aatttcttta tagtcttctt taggttttcc tttccatcgg tttacttcta cttttatgaa
    13921 cttgtattcg tacattgctg tataatcctc cggaagtgta ttggaatcgt taccttgttt
    13981 ttcgattatg ataaacttga atccataaat agagcgcgca gcctattaaa agtattggaa
    14041 attgccatcc tgtatttccg tttttaaaat aatctattaa tgaccatatc agtaaagcga
    14101 cagtataaaa actaaatgct attctggcgg ctatacccga ttggtgtttt tgcatctcat
    14161 ccattttctt cataagaacc gctcccttaa ttttttttgg cgttatagtt gaatacttta
    14221 tctattcccg tatttaatgc gtgagctatc gaaaaagcca gacctaaagt cgggtcatat
    14281 ttattatttt caattgcatt gatggtttgc ctggtcacat tgcagagctt agccagatca
    14341 ttttgtgaaa tatcagctgc tgttctaagt ttttttatat tgttatccac taaaaccctc
    14401 cttaaatatt tttgttttca ttttaaattt tcaaatttat atatatttat tt
//
