LOCUS       c00187_gnlPro..        14686 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HCFINGKG_190.
ACCESSION   c00187_gnlPro..
VERSION     c00187_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 10:02:40
            Original ID  :: gnl|Prokka|HCFINGKG_190
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14686
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14686
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[153:4686]"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      154..4686
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /neighbourhood="10000"
                     /product="fatty_acids-unassigned"
                     /protocluster_number="1"
     cand_cluster    1..14686
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /kind="single"
                     /product="fatty_acids-unassigned"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14686
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="fatty_acids-unassigned"
                     /region_number="1"
                     /rules="(not (EC1_2-faecali or baiH or baiCD or
                     ECH1_Enoyl_CoA_DH1 or ECH1_Enoyl_CoA_DH2 or
                     ECH1_Enoyl_CoA_DH3 or ECH1_Enoyl_CoA_DH4 or POR or POR_N or
                     PFOR_II) and minimum(4, [AcetylCoA_hyd_C, Acyl-CoA_dh_1,
                     Acyl-CoA_dh_2, EC1_2-faecali, ECH1_8_CARC, ECH_1, ECH_2,
                     HBT, HCDH, HCDH_N, Thiolase_C, Thiolase_N,
                     ketoacyl-synt]))"
                     /tool="gutsmash"
     CDS             2..178
                     /locus_tag="ctg187_1"
                     /transl_table=11
                     /translation="IREHREASKSELVFRASPEYKILYSLVNEQQNELEIDIHFGFKLI
                     IRGGGTCKRLILQ"
     CDS             154..924
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg187_2"
                     /sec_met_domain="ECH_1 (E-value: 1.8e-67, bitscore: 217.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTVDFTVKNHVGWLTLNRPDKLNALNETMNREIMDVLTAAEQDP
                     QIRALVLTGAGRAFCSGEDLGSLNEQADHGEIIRKRYIPMVKKIAAFEKPLIAAVNGPA
                     AGAGFSLCLACDFRIASEQATFLNAFIHIGLVPDTGNLYFLPRIAGYAKALELSCLGEK
                     ISAPEAMEYGLLTKVVPACHLEKETQHFAERLAAMPTKAIGLIKRYMQKSFESTLDEML
                     EKEAYAQRIAGQTADHQEGVRAFFEKRKPEYKGN"
     CDS             1004..2461
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg187_3"
                     /sec_met_domain="Aldedh (E-value: 5e-181, bitscore: 592.6,
                     seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVINGEPVDAAGRETFHVYNPATGEPIATVPKADYADADRAVEAA
                     RHAFEHGKWRRYPVGKRARVLNKIASIMRSRFDALVEMEILNTGKTTETAKGQVMQAIE
                     DFEFFAGAIVGHRGAVNHVPGQFFNYTQKEPVGVAAQIIPWNYPLMMAAWKIAPAIAAG
                     CSVVVKPASLTPITAILLAEICHEAGVPAGVVNVITGPGAKIGSYLAKHEGVDKIAFTG
                     ETSTGKEIMANASETLKRVTLELGGKSPNLVFRDADIDAAVNGALYGIFYNTGQSCEAR
                     SRLFLQEEIYDAFMEKFVAKTKKLVLGDPFSPASHIGAIISKGQLETIHRYVEEAKQAG
                     ATIVTGGKPAKVEGFENGYWYEPTIITNVTNDSKIAQEEIFGPVVVVMPFKEEKEAVKL
                     ANATKYGLASSIWAKDQGLIKRVADSIQAGIVMVNSPFSAFPGTPFGGYKQSGFGRELS
                     FECLDLYSETKSVLTYAGAKPLNPFQL"
     CDS             2618..3484
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: HCDH"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg187_4"
                     /sec_met_domain="HCDH (E-value: 2.5e-34, bitscore: 108.4,
                     seeds: 68, tool: rule-based-clusters)"
                     /sec_met_domain="HCDH_N (E-value: 1.2e-61, bitscore: 198.2,
                     seeds: 60, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMAETLVVIGSGVMGRGIAYAGALGGFKVRLVDVRPDILHQAENI
                     IGSVMEKGLARGKINGADAERIKANIEYTVDLPAVAGSADVIIEAVPEKMEIKKEVFEK
                     MDRFAPAGCILATNTSTMSPTEIGSFTTRPASVIAMHFFNPVHKMPLVEIIRGLETSDE
                     TVQRAEKAAEKMGKETVIVNEFPGFVTSRISCLVGNEAFCMLQEGVGTAEEIDKAIKLG
                     LNFPMGPFELADLVGLDARLNNLRHLHEKLGEKYRPAPLLEKYVKAGRLGRKTGKGVYD
                     YTTVEGE"
     CDS             3487..4686
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     fatty_acids-unassigned: Thiolase_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg187_5"
                     /sec_met_domain="Thiolase_N (E-value: 4.5e-85, bitscore:
                     275.6, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="Thiolase_C (E-value: 3.4e-52, bitscore:
                     165.9, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDVVIVDAVRTPIGRYKGALKSVRPDDLAASAIKALLARHPEVP
                     WNEIEEVILGNANGAGEENRNVARMAALLAGLPVETAGTTVNRLCGSGLDAVNIAAKAI
                     MAGDGDIYIAGGTESMTRAPFVMAKPENGYPRGNLEMFDTTIGWRFVNEKLKKMYGTDS
                     MPETAENVAKQFHISREAQDAFAFTSQMRAKAAMEANRFQDEIVPVVYTDQKGESVSVI
                     RDEHPRPDTTPEKLARLKPLFAGGTVTAGNSSGINDGASAVLLMSAEKAVQLGIKPMAR
                     FAASATAGLEPRLMGLGPVYATRKALKRSGFNISDIDLVELNEAFASQSIACIRQLELD
                     SDIVNVNGGAIAFGHPLGASGARILTTLVHEMQKRKAKRGLATMCIGVGQGIATVIEKI
                     "
     CDS             4729..5622
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PaaX"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg187_6"
                     /sec_met_domain="PaaX (E-value: 6e-34, bitscore: 106.8,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKTLNTRSMIFTLYGDYIRHYGSEIWIGSLIKLLEAFGHHEQSV
                     RAAISRMSKQGWVESRKEGNNSYYSLTERGVKRMNEAAGRIFKLNPGKWDGKWRFFLYT
                     IPEKKRNIRDELRKELVWSGFGLLLNSVWLTPNDLLDEMKGIIDKYGINEYVKIFTAEN
                     VWGKSDKELVHELWDIDYMNDRYEDFMAHYREKYESVKEKMKRGEMTNQDCFVERTLLV
                     HNYRKLLFVDPGLPEELLPEKWKGEEAAALFRDYYRILAKPANDFFEDIFSEGYGTFQK
                     SKHYDVFDHPLITEKA"
     CDS             5653..6603
                     /locus_tag="ctg187_7"
                     /transl_table=11
                     /translation="VANPVTEMLGIKFPVFQGGMGNISDPALAASVSNAGGLGTIGAGT
                     LPVAEIEKRMDKMRSLAASPCCVNIAISVHPNASEVIRLAIEKKIPVVSLSAGNPSKYI
                     PVLHQNGIKVICVSSTVRQAKKAEAAGADIIVCEGYEAAGINAANESTTMVLVPQIVKA
                     VSIPVVAAGGIADGKGLAAALSLGAYGVQMGTRFIATKEAQFHPVYKNAVIEATDEATM
                     IIGRPYQMLRRVFKNVYAGYLRELEESGADPGRFKKLTSEAHHERGALQGDMEHGFING
                     GQIAGLIEDCPSVAQLLEEMVKEARAVLTRSMARL"
     CDS             6764..7648
                     /locus_tag="ctg187_8"
                     /transl_table=11
                     /translation="MEIDAVFSGGGIKGLALIGALEVLEKKGFTFKRLAGTSVGSVFAG
                     LRAAGYTSGEMKQMLAETDTAAFLDQRKPLLPVPFAKWLLLYWRLGLYRGTAFEEWIGE
                     KLASKGVYTFKDVPKGSLYFTASDLTHNRLVVLPDDLERYGVPWQTFPVAKAIRMSCSI
                     PYFFEPVRLRSLEGTSLIVDGGVLSNFPMWLFVKPEEKKARPVLGITLSPKQPEEPDVE
                     IKNAIQLFDALFKTMKDAHDARYISRKLEKDIIFIAVDGVTATDFQLSAAQKAALIEAG
                     RKKTETFLKTWSY"
     CDS             complement(7665..8033)
                     /locus_tag="ctg187_9"
                     /transl_table=11
                     /translation="LLKTRQWIIAGIFLLALVGLGSSLFHEPVVFLKRVLIAFIFAAVL
                     LAGIRFLLKRSTNVSNQEQKAFLKAARKSRKRMKKRNMKVHTVHTVKFSKRPLRKKSNV
                     QLTVIEGKKGKKKNRAVY"
     CDS             complement(8189..9067)
                     /locus_tag="ctg187_10"
                     /transl_table=11
                     /translation="MFGGKRHSVTAIRRKNNRIDFFYLPKETRPSVQKLKKIPFLRGII
                     AIIESSANGAKHLNFASERYDVDPEEDEKRKEAAPAKTTVVLGVAAAGVLSFLFAKFFM
                     TLIPVFLAELARPFFPGDAAQILIEGAFKLLLVLSYIYLISLTPFIKRVFQYHGAEHKV
                     INTFENGLALTVENVRSQSRLHYRCGSSFILFTVIVSVLIYTLVPTDPLWLRITDRILL
                     IPVVLGTAFEVLQLTNKVRHIPVLKYLGYPGLWLQLLTTKEPDDKQIEVAISSFQALLE
                     LESGDTDSAAR"
     CDS             9297..9815
                     /locus_tag="ctg187_11"
                     /transl_table=11
                     /translation="MENGSKVLKNQEHSMTFFQMVLVTGFAGGIIWSLVAYLYFSFHFT
                     AIEPNVLLEPFTVGSWRNMWIGKIISILVYGLLSTGCALVYYLFFKKLKSMWVGAIYGL
                     CLCAVVLIVLNPIFPGMKPFLKLDANTIITCCCIYILYGVFIGYSISFEYERSRVFKRK
                     LERQTNPLP"
     CDS             9942..10397
                     /locus_tag="ctg187_12"
                     /transl_table=11
                     /translation="MKKYLVLNGPNLNLLGQREPGTYGKDSLKTLMARMEAAARKHGVA
                     IGFFQSNHEGALIDKLHAAGDEGFAGIIFNPGAFTHYSYALRDAISAIRLPVIEVHISN
                     IHAREEFRHHSVTAAVAQGQIAGFGLYGYELALMALLEAEKGEEERC"
     CDS             10391..11452
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M24"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg187_13"
                     /sec_met_domain="Peptidase_M24 (E-value: 1.3e-70, bitscore:
                     227.8, seeds: 437, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKLEKLRETFPQAGIDGLLITSPYNRRYMSNFTGTTGIVLISGE
                     AAKFITDFRYVEQASKECEGYEIVQHQGPVEQEVAKQVEAMGIKRLGFEQDHMSYALFK
                     TYEGLLDAELVPVSGLVENLRLIKTDAEIKILKEAADIADAAFKHILDFLKPGVTELEV
                     SNELEFFMRKCGATASSFDTIVASGLRSAMPHGVATDKVIEKGDLVTMDYGALYKGYCS
                     DITRTVAVGEPSGQLKKIYNIVLESQLLAVQNIKPGMSGIEADAISRNYIARKGYGDAF
                     GHSLGHGIGLEIHEGPNLSMRSAYTLEPGMVVTIEPGIYVPGVGGVRIEDDTVITENSN
                     ELLTHSAKELIIL"
     CDS             11502..12059
                     /locus_tag="ctg187_14"
                     /transl_table=11
                     /translation="MISVNDFRTGLTIEVDGGIWRVLDFQHVKPGKGAAFVRSKLRNLR
                     TGAIQEKTFRAGEKVERAQIDNRRMQYLYANGDQHVFMDTETYEQIELSSAQIKDELQY
                     LLENMEVQMIMYQGETLGIELPNTVTLTVTHTEPGVKGDTATGGSKPATLETGLTVQVP
                     FFVNEGDKLIINTTDGSYVSRA"
     CDS             12268..13194
                     /locus_tag="ctg187_15"
                     /transl_table=11
                     /translation="MEDLLDILPKTLSKQLEKLGDMLEDVEEIRIRVNRPLEITSKGIP
                     HFLRYTPTESDAEQLINRLANFSFYALEEELKKGYVTISGGHRVGFAGKVILENGQVKA
                     IRYFSSFNIRIAREKIGTADPYLFALHNGRWLSAMIIGAPQTGKTTFLRDIARLISSGI
                     PERGISPAKVGIVDERSEIAGCVHGIPQLHFGPRVDVLDACPKAEGMMMLIRSMSPDVI
                     VVDEIGREEDAAAIMEAVNAGISLVMTTHGENFRDIQKRPILKKILESYAFDRFLELSR
                     GSRPGRVTAVRDAEGNIIRTGEGVSRA"
     CDS             13187..13702
                     /locus_tag="ctg187_16"
                     /transl_table=11
                     /translation="VLKLFGAALIVLATSFIGFEAAKRLSERPRQLRIFQNALQALEVE
                     IMYGHTPLHEAARKLSGQLPDPAAAFFRSFASQLTTLETTVKEAWEKSLDGIWKLTALK
                     ENEYEVLRQLGENLGKHDRYTEQKQLLLALSHLEREEKEAHERQLRYEKMAKSLGVLTG
                     LLIAILLI"
     CDS             13733..13936
                     /locus_tag="ctg187_17"
                     /transl_table=11
                     /translation="MGIDVDIIFKIAGVGIVVAFLHTILDQVGKKEYAQWVTLLGFLYI
                     LFLVASIVGDLFSKIKTVFLFQ"
     CDS             13986..14360
                     /locus_tag="ctg187_18"
                     /transl_table=11
                     /translation="VALITTFLALILKEQKPNFAFLLTLFAGCFIFLFLVDKIYEIIHL
                     LQKIAQKGNVDTMYIETILKIIGVAYIADFAANITKDAGQGALAAKVELAGKIIILTMA
                     IPILTVLIETIVNLVPRAGS"
ORIGIN
        1 tatccgggaa catcgcgaag cgtccaagtc cgaacttgta ttccgggcga gcccggaata
       61 caaaatctta tattcacttg tcaatgagca gcagaatgaa ctggaaattg acatccactt
      121 tggatttaaa cttattatac gaggaggggg gacatgcaaa cggttgattt tacagtaaaa
      181 aatcatgtcg gctggctgac gctgaaccgt ccggataaac tcaatgcttt gaatgaaacc
      241 atgaaccggg aaatcatgga cgttttaaca gcagctgaac aagatccgca aatacgtgca
      301 ctggtcctca ccggtgcagg ccgggccttc tgttccgggg aggatttggg cagtttaaac
      361 gaacaggccg atcacggtga aatcatccgg aaacgctaca tcccgatggt aaagaaaatc
      421 gcggcttttg aaaaaccgct cattgccgcc gtgaacgggc cggcggcggg cgcaggcttc
      481 agcctctgcc tggcgtgtga tttccggatc gcatccgaac aggccacttt tttaaacgcg
      541 tttattcata tcgggcttgt gccggatacc ggaaatctct atttcctgcc aagaattgca
      601 ggctacgcca aagcgttgga actctcttgc ttaggggaga aaatcagtgc accggaagcc
      661 atggagtacg ggcttttaac gaaagtggtt ccagcctgcc atctggaaaa ggaaacacag
      721 cattttgctg aaaggcttgc tgcaatgccg acaaaagcaa tcggcctcat taagcggtac
      781 atgcaaaaaa gctttgaaag cacattggat gaaatgctcg aaaaagaagc atacgcccag
      841 cggattgcag ggcaaacagc cgaccatcag gaaggggtcc gggcattttt tgaaaaaaga
      901 aaacctgaat acaaaggcaa ttaaacagaa agggtgaaca tgaatgccag taacaaaaga
      961 agcggcagca tttcctgctg aaatgaaacg gagcgcgtat aaaatggtga tcaacggaga
     1021 accggtggat gcagccggcc gcgaaacgtt ccacgtctat aatcctgcaa ctggcgaacc
     1081 aatcgccacg gtgccgaaag cggattacgc ggatgccgac cgggccgttg aggcggcgcg
     1141 ccatgctttt gaacacggaa aatggaggcg ttatccggtt ggaaaacggg cgcgcgtcct
     1201 gaacaaaatt gcctccatta tgcgcagccg ttttgatgcg cttgttgaaa tggaaatttt
     1261 aaataccgga aagacgactg agacggcaaa ggggcaggtg atgcaggcca ttgaagattt
     1321 cgagtttttc gcaggagcga ttgtcgggca tcgcggcgct gtgaaccatg ttcccggcca
     1381 gttctttaac tatacccaaa aagaaccggt tggggtcgct gcccagatca ttccatggaa
     1441 ttacccgctc atgatggctg cgtggaaaat tgccccggcg atcgcagcag gatgctctgt
     1501 tgtggtaaag ccggcaagcc ttacgccgat tacagccatt ttactggctg aaatctgcca
     1561 tgaggccggt gttccggcag gcgttgtgaa cgtgattacc gggccggggg cgaaaatcgg
     1621 gtcttatttg gcgaagcatg aaggggtcga taaaatcgct tttaccgggg aaacttccac
     1681 cggaaaagag atcatggcaa atgcctcgga aacattgaaa agagtcacgc tggaacttgg
     1741 cggaaaatct ccgaatctcg tatttcggga tgccgatatc gatgccgccg tcaatggcgc
     1801 cctgtacggc atcttctata ataccgggca atcgtgcgaa gcgagatccc gtcttttcct
     1861 gcaggaagaa atttacgatg cgtttatgga aaaatttgtg gccaaaacga aaaaactggt
     1921 gctcggtgac ccgttttcac ctgcctctca tatcggggcg atcatcagca aagggcagct
     1981 ggaaaccatc caccgctatg tcgaagaagc aaagcaggcc ggcgcaacca tcgtgacagg
     2041 cggaaaaccg gctaaagtgg aagggtttga aaatggttac tggtatgaac cgaccattat
     2101 cacaaacgtc accaatgaca gcaaaattgc ccaggaagaa atttttgggc cggttgtggt
     2161 ggtgatgcct tttaaagagg agaaggaagc cgtaaaactt gcaaatgcga cgaagtacgg
     2221 cctggcttca agcatctggg caaaagacca gggcctgatt aagcgggtcg cggacagcat
     2281 ccaggcaggc attgtcatgg tcaacagccc gttctccgca tttccgggga cgccgttcgg
     2341 cggatataaa caatccggtt tcgggcgcga attaagcttc gaatgcctcg atttatacag
     2401 cgaaaccaaa agtgtgctca cttatgcagg ggcaaaacct ttaaacccgt ttcaattgta
     2461 agcttccggc ccaataaagg cgctcattgc ggcacgtgca gtgaaacgga tccggcgggg
     2521 caggatggac aaataagaag cggacgcatt ctttcgggat gggttcgctt cttttaaaaa
     2581 tcatcgcaaa agatagaaaa tttgaagagg aagtggtatg atggcggaaa cattggttgt
     2641 cattggttca ggggtaatgg ggcgcggcat cgcttatgcg ggcgcactcg gcggtttcaa
     2701 agtcaggctg gtagatgtcc ggcctgacat cctgcatcaa gcggaaaaca taatcggatc
     2761 cgtcatggaa aaagggctgg cgagggggaa aatcaacggg gcagacgctg aaaggataaa
     2821 ggcaaatatc gaatataccg ttgatttgcc ggcagtagcc ggttctgcag atgtgatcat
     2881 cgaggcagtg ccggaaaaaa tggaaataaa aaaagaagtg tttgaaaaaa tggacaggtt
     2941 tgcgcctgcc ggttgcatcc ttgcgaccaa tacatccacc atgagcccga ctgaaatcgg
     3001 ttcttttacc acccgccccg catctgtcat tgccatgcat tttttcaatc cggtgcataa
     3061 aatgccgctt gtcgagatca tcagggggct tgaaacaagc gatgaaacgg ttcaacgggc
     3121 tgaaaaagca gcggaaaaaa tggggaaaga aacagtgatc gtgaatgaat ttcccggctt
     3181 tgttacaagc agaatcagct gtttggttgg aaatgaagcg ttctgcatgc tgcaggaagg
     3241 ggtggggaca gcggaagaaa tcgataaagc catcaaactc ggcttgaatt ttccgatggg
     3301 gccgtttgaa ttggcggatc tggtcgggtt ggatgcaagg ctaaacaatt tgcgccactt
     3361 gcatgaaaag cttggcgaaa agtaccggcc ggcgccttta ctggaaaagt atgtgaaagc
     3421 gggccggctt gggcggaaaa caggcaaggg cgtatatgat tacacaacgg ttgaaggaga
     3481 atgaagatga gagacgtcgt catcgtggat gcggtcagaa caccgattgg gcgatataaa
     3541 ggcgcattaa aatcagtaag gccggacgat ctggcggcaa gtgccatcaa ggcgttgctc
     3601 gcccgccatc ccgaagtccc ctggaacgaa atcgaagaag tcattctcgg aaatgcgaac
     3661 ggcgctggcg aagaaaaccg gaatgtcgca agaatggctg cactgctcgc cgggcttccg
     3721 gtcgaaaccg ccggcacaac cgttaaccgc ttatgcggat caggcctcga tgctgtcaat
     3781 attgcagcga aagcgattat ggctggtgac ggggacatct atattgccgg cgggacggag
     3841 agcatgacaa gggcgccttt tgtcatggca aagccggaaa acggctaccc gaggggaaat
     3901 ctggaaatgt ttgacacaac gatcggatgg agatttgtaa atgaaaaatt aaagaaaatg
     3961 tacgggacag acagcatgcc ggaaacagcg gaaaatgtcg caaagcaatt ccacatcagc
     4021 cgggaagcgc aggatgcctt tgcttttacg agccaaatga gggcgaaagc ggccatggaa
     4081 gcaaaccgct ttcaagatga aatcgtgcct gtcgtgtata cggatcagaa gggggaatcc
     4141 gtatctgtca tccgggatga acatccccgc cccgatacta cgccggaaaa actggcaagg
     4201 ttgaaaccgc tttttgcagg aggcacggtg actgccggaa attcatccgg catcaatgac
     4261 ggggcgtctg ccgtgctatt gatgagcgcg gaaaaagcgg tccaattggg catcaaaccg
     4321 atggcccggt ttgccgccag cgcaacggca gggctggaac caaggctcat ggggctgggc
     4381 ccggtgtatg caacgagaaa agcattaaag cgttccggat tcaatatttc ggatattgat
     4441 cttgtagagt taaatgaggc ctttgcttcc cagtccattg catgcatccg gcagctggag
     4501 ctggacagtg atattgtcaa tgtaaacgga ggggcgattg cgttcgggca tccgctgggg
     4561 gcaagcggcg cgagaatttt aacaacgctc gtccacgaga tgcaaaaacg aaaggcaaaa
     4621 cgggggctcg ctacgatgtg tatcggggtg ggccagggga ttgcaaccgt tatcgaaaaa
     4681 atttaaaatg ggggaaagac atctttggca gagacaagga gcttataaat ggaaaaaacg
     4741 ttaaatacgc gttcgatgat ttttacgctg tatggcgatt acatccgcca ttacggaagc
     4801 gaaatttgga ttggcagttt aattaaattg ttggaagcgt tcggccacca tgagcaatct
     4861 gtccgcgccg ccatttcccg catgagcaaa caaggctggg tggaaagccg caaagaagga
     4921 aacaatagtt actattcttt gactgaacgc ggtgtcaaac ggatgaacga ggccgccggg
     4981 cggattttta aactgaaccc gggcaaatgg gacggcaaat ggcggttttt tctgtatacg
     5041 atacccgaaa aaaagcggaa catcagggat gaactgagaa aagaactggt gtggagcggc
     5101 tttggcctcc tgttaaacag tgtctggctt acgccgaatg atttgctgga tgaaatgaaa
     5161 gggattatcg acaaatacgg gatcaatgaa tatgtcaaaa tcttcactgc cgaaaacgta
     5221 tggggcaaat ccgacaaaga acttgtgcat gaattatggg atattgatta tatgaacgac
     5281 cgttatgaag attttatggc ccattaccgg gaaaaatatg aaagcgtcaa agaaaagatg
     5341 aaaagagggg aaatgaccaa ccaggactgc tttgtcgaac ggacgctgct tgttcataat
     5401 taccggaaac tattgtttgt ggatcccggt ttgccggaag aactgctgcc tgaaaagtgg
     5461 aaaggggaag aagcagccgc gcttttccgg gactattacc ggatccttgc caaaccggca
     5521 aatgattttt ttgaagacat tttttccgaa ggatacggca cttttcagaa aagcaaacat
     5581 tatgatgtgt ttgaccatcc tcttataact gaaaaagcat aaccggatcc gtgcgcagaa
     5641 aggagcgata aagtggcaaa tccggtaact gaaatgctgg gcatcaaatt tccggttttt
     5701 cagggcggga tgggtaatat cagtgatcct gcccttgctg caagtgtttc caacgccggc
     5761 gggctgggaa cgattggcgc cggaacactg cctgtagcgg aaatcgaaaa aagaatggac
     5821 aaaatgcgca gcctggccgc ttccccctgc tgcgttaata ttgccatttc ggttcatcca
     5881 aacgcgagcg aagtaatccg gttagccatt gaaaagaaga ttccggttgt ttccttatct
     5941 gccggcaacc cttcaaaata tatcccggtt ttgcatcaaa acggcataaa agtgatttgt
     6001 gtctcctcca ctgtccgcca ggcgaaaaaa gcggaagcag cgggggctga catcattgta
     6061 tgcgaaggat acgaggcagc agggatcaat gctgccaatg aaagcacgac aatggtgctc
     6121 gttccgcaga ttgtaaaagc ggtcagcatt ccggttgtcg ctgcgggagg gattgcagac
     6181 ggcaaaggtt tggcggcggc actttcgctc ggggcatacg gcgtgcaaat ggggacgaga
     6241 ttcatcgcga caaaagaagc gcagtttcac cctgtatata agaacgctgt gattgaagca
     6301 acagatgaag cgacgatgat catcggaagg ccctaccaaa tgttgcgcag agtgttcaaa
     6361 aatgtgtacg caggctatct ccgcgaactg gaagaaagtg gtgcggatcc gggccgcttt
     6421 aaaaagctga caagcgaagc ccatcatgaa aggggagcgc ttcaaggcga tatggaacac
     6481 ggttttataa acgggggcca aattgccggc cttattgagg actgcccgtc tgttgcccaa
     6541 ttattagaag aaatggtaaa agaagcacgg gctgtgctaa ccaggagcat ggcgcggtta
     6601 taatcccgta agaactcttt gttctaattc ctttccttat gcgctaaaat aataaaaaag
     6661 catttttttc atctttcgtt caagcggggc atcctgccaa cattccgcat tttttctgac
     6721 caacaaaccg aaacgcccgg tgcaaatcca agggtggatt tccatggaga ttgacgcggt
     6781 gttttccggc ggaggcataa aaggccttgc gctcatcggg gcattggaag ttttggaaaa
     6841 aaagggattt acgtttaaac ggctggccgg cacaagcgtc ggctccgttt ttgcagggct
     6901 gcgggctgca ggctatacaa gcggcgaaat gaagcaaatg cttgcggaaa cagacacggc
     6961 cgcgtttctt gaccagcgaa aaccgctgct gccggtgccg tttgcgaaat ggctgctgct
     7021 gtattggcgg ctcgggttgt acaggggcac cgcgtttgag gaatggatcg gggaaaaact
     7081 cgcatctaaa ggtgtgtaca cgttcaaaga tgttccaaaa ggctcccttt atttcacggc
     7141 atccgatctt acccataacc ggcttgttgt tttgccggat gacctggaac gttacggggt
     7201 tccatggcaa acctttccgg tggcaaaggc cattcggatg agctgcagca ttccatattt
     7261 tttcgaaccg gtacggttgc gctcgctgga aggcacaagc ctcattgtag acggcggggt
     7321 attaagcaat tttccgatgt ggttgtttgt caaaccggaa gaaaaaaagg cgcggccggt
     7381 gctcggcatt acgctcagcc cgaaacaacc ggaagagccg gatgtggaga taaaaaatgc
     7441 gatccagctg ttcgatgccc tgttcaagac gatgaaagac gcccatgatg cccgctatat
     7501 ttcaagaaaa ctggaaaaag acattatttt tatcgctgta gatggcgtga ctgctacaga
     7561 ttttcagctt tccgccgcac aaaaagcagc cttaatcgag gcgggtcgga aaaaaacaga
     7621 aacgtttctg aaaacgtggt cctattaata aaaaagaatc gagcttagta gacagctcga
     7681 tttttctttt tgcccttttt gccttcaatc acggttaact ggacattgga ttttttgcgc
     7741 agcggccgtt ttgaaaattt aaccgtgtgg acagtatgga ccttcatatt cctttttttc
     7801 attcttttcc tggatttgcg ggcggctttt aaaaatgctt tttgttcctg gttggaaaca
     7861 ttcgtgcttc tcttgagcag gaaacgtatg ccagccaaaa gcactgccgc aaaaatgaag
     7921 gctatcaaca cccttttcaa gaatacaacc ggctcatgaa acaaagagga acccaggccg
     7981 accagggcca aaagaaaaat gccggcgatg atccattgac gcgtcttcaa caaaagccac
     8041 ctcctcatgt tttcccaacc attttttcca tcattctatc agtttatacg gatccggccg
     8101 tttttatttt gaggttgatt ccccgtcgca caaacaagct tgtgatagta aatgtattcc
     8161 catgcgctgg aaatttcaaa cgccgttttt aacgggcggc agaatccgta tcacccgatt
     8221 ccagttcaag cagcgcctga aaggaggaaa tcgcgacttc aatttgcttg tcatccggct
     8281 cttttgtcgt taacagctgc agccacaggc ccggatagcc aagatacttc agaaccggaa
     8341 tatggcggac tttattggtc agctgaagga cttcaaacgc cgtgccgagc acgaccggaa
     8401 tgagcaaaat ccggtcggtg atgcggagcc agagcggatc tgtcgggaca agcgtataaa
     8461 tcaggacgct cacaatcacg gtaaacagaa taaaactgct gccgcaccgg taatgcagcc
     8521 tcgattgcga gcggacgttt tcaacggtca gggcaagccc gttttcaaat gtattgatga
     8581 ctttatgttc agccccgtgg tattggaata cccgcttgat aaacggcgtt aaagaaatca
     8641 aataaatata cgaaagcacg agcagcagtt taaacgcgcc ttcaatgaga atttgcgcgg
     8701 catccccggg aaaaaacggc cttgccagtt ctgccagaaa aacgggaata agcgtcatga
     8761 aaaatttggc aaacaaaaag gacaagacgc cggcagcagc cacgccgagc accacggttg
     8821 tttttgcggg ggctgcttcc ttccgttttt cgtcttcttc cgggtcaaca tcataccgct
     8881 cgcttgcaaa attcaaatgc tttgctccgt ttgcggatga ttcaatgatg gcaatgatcc
     8941 cacgcaaaaa cgggattttt ttcaattttt ggacggacgg gcgcgtctct tttggcagat
     9001 aaaagaagtc gatccggttg tttttgcggc ggatggcagt gaccgaatgc cgctttccgc
     9061 cgaacataac cccttccacg actgcctggc cgccataaac tggttttgtc aatttctttt
     9121 cccccaaacc tgaacttcaa atgcttcttt cccgtttaac ctgaaaacgg agtggatttc
     9181 cgaaacgata ttcactctta ttttactaaa tcattttaaa tacgactagg ggaaagactt
     9241 gtgggaaaga taagaaagaa aagatgcatg ccgtcacatg tgaaggagtg gaaaatatgg
     9301 aaaatggcag caaagtatta aaaaaccagg agcattccat gacctttttt caaatggtgc
     9361 ttgtgaccgg atttgcgggc gggatcattt ggagcctggt tgcttattta tacttttctt
     9421 ttcattttac ggcgattgaa ccgaatgtcc tgcttgaacc atttacagta ggatcctggc
     9481 gcaatatgtg gatcggaaaa atcatttcca tattggtata cggattgctt tctaccggct
     9541 gtgcccttgt ctattatctt ttctttaaaa aattgaaatc gatgtgggtc ggcgcgatat
     9601 acgggctttg cctgtgcgca gtcgtcctca ttgtgctgaa tccgattttt cccggcatga
     9661 aacctttttt aaaactggat gccaatacga tcattacctg ctgttgcatt tacattctct
     9721 acggcgtgtt tatcggttat tcgatttcat ttgagtatga aagaagccgg gtttttaaaa
     9781 gaaaactgga gaggcagacg aacccgctgc cgtaaatcga tccgggcggg aggaacgccc
     9841 cggattcagg cgcaagcatg cggccgaaaa gttaaaaaat agaaattttc ttcaatttat
     9901 ggtaaaatgg gcacgttaaa tatgggaaaa aggtgcttga aatgaaaaaa tacctcgtat
     9961 taaacggccc aaatctgaat ttgctcgggc aaagggaacc cggcacttac gggaaagatt
    10021 cgttaaaaac cctgatggcg cgcatggaag cggcggcccg aaagcacggc gtcgccatcg
    10081 gtttttttca atccaaccat gaaggcgccc tgattgacaa gctgcacgct gccggggatg
    10141 aaggctttgc agggattatt ttcaatccgg gcgcgttcac gcattacagc tatgctttgc
    10201 gggacgcgat cagtgccatc cgcctaccgg tgattgaagt tcatatttcg aacatccatg
    10261 cccgcgagga attccgccac cattctgtaa cggcggctgt tgcgcagggg caaattgcag
    10321 gcttcgggct gtacggctat gagcttgccc tcatggcctt gcttgaggca gaaaagggag
    10381 aggaagaaag atgttaaaac tggagaaact gagagaaaca tttccgcagg ccggtattga
    10441 cggcttgctc attacaagcc cgtataaccg ccgctatatg tccaatttta cggggactac
    10501 cgggattgtc cttatatccg gggaagcggc aaaatttatt acggacttcc gctatgtcga
    10561 gcaggcatcg aaagagtgtg aaggctacga aatcgtccag catcaggggc cggtggaaca
    10621 ggaagtggcc aaacaggtgg aagcaatggg gatcaaacgg ctcgggtttg agcaggacca
    10681 tatgagctat gcgcttttta aaacgtatga agggctgctc gatgcggaac tggtcccggt
    10741 ttccggcctt gttgaaaatt tgcgcttgat caaaacagat gcggaaatta agatattaaa
    10801 agaggctgcg gatattgcgg atgctgcctt taaacatatc cttgacttct taaaaccggg
    10861 cgtcacggaa ttggaagttt ccaatgaact ggaatttttc atgaggaaat gcggcgcgac
    10921 tgcttcttca tttgatacca ttgtcgcatc cggcctccgc tctgccatgc cgcacggggt
    10981 ggcgacggac aaggtgatcg aaaaaggcga tttggttacg atggattacg gcgcgctcta
    11041 taaaggctat tgttcggata ttacaaggac ggttgcggtc ggcgagcctt ccgggcaatt
    11101 gaagaaaatc tacaatattg tgctggaatc gcagctgctt gccgtccaaa acatcaaacc
    11161 gggcatgtcc ggtattgaag cagacgccat ttcccgcaat tatatcgccc ggaaaggtta
    11221 cggcgatgcg ttcggccatt cccttgggca cgggatcggc cttgaaatcc acgaaggccc
    11281 gaatctttcc atgcgctcgg cctatacttt ggaaccgggc atggttgtca ccatcgaacc
    11341 gggcatttat gtgccgggtg tcggcggcgt ccggattgaa gacgatacgg tgattaccga
    11401 aaattcgaat gaattgctga cgcattccgc aaaagaactg attatattat aatagttaca
    11461 gccctcaaca ggggatcgaa tgaacatgta ggaggaaaaa tatgatttca gtaaacgatt
    11521 ttcgcaccgg cttaacgatt gaagtggacg gcggcatctg gcgcgtcctc gatttccagc
    11581 atgttaagcc gggaaaaggc gccgcttttg tgcgctcgaa gcttcgcaat ttgcgtaccg
    11641 gcgctatcca ggaaaaaacg ttccgtgccg gcgaaaaagt tgaaagggca cagatcgaca
    11701 accggagaat gcagtattta tatgcaaacg gcgaccagca cgtatttatg gatacggaaa
    11761 cgtatgaaca aatcgagctg agtagcgccc aaattaaaga tgagctgcaa tacttgctgg
    11821 aaaacatgga agtgcaaatg atcatgtacc agggagaaac gctcggcatt gaactcccga
    11881 atacggtcac gctgacagtt acccatacag aaccgggggt aaagggcgat acggcaacag
    11941 gcgggtccaa accggccacg cttgaaaccg gcctgacggt acaggtgcct ttctttgtca
    12001 atgaaggcga taaattgatc atcaatacaa cggacggttc atacgtgtcc cgtgcctgat
    12061 ttctttgaaa aaagcttggc gtcccaaacg gcgccaagct tttttgcttt tccggcaaga
    12121 gacaggcaaa aataagttta cataatcatg ttataaataa cttaaacttt cagcatctgc
    12181 ctcgcttcct tgtcatagtt ttcaaacccg gcgaatagat tgtactatcc atgaaccaaa
    12241 ctgtatgttt tgaaagcagg gatgaagatg gaagatttgc tggacatttt gccgaaaacc
    12301 ttatccaaac agctggaaaa attgggggac atgctcgaag atgtggaaga aatccgcatc
    12361 cgcgtaaacc gcccgcttga aattacttca aaaggaatcc cgcatttttt gcgctatacg
    12421 ccaacggaga gcgatgctga gcagttgatc aaccggcttg cgaatttctc tttttacgcc
    12481 cttgaagaag agctgaaaaa gggatacgtc acgatcagcg gcgggcatcg tgtcggattc
    12541 gcggggaaag tcattcttga aaatggacaa gtaaaggcga tccgctattt ttcatctttt
    12601 aatatccgga ttgcccggga aaaaatcggg actgcggatc cttatctttt cgcccttcac
    12661 aacgggcgct ggctgtccgc gatgatcatc ggggcgcccc agaccggaaa aacgactttt
    12721 ttaagggata tcgcgcggct gatttcaagc ggcatcccgg aacgcgggat ttcgcctgcc
    12781 aaagtgggga ttgtcgacga acggtctgaa attgccggct gcgtccacgg catcccgcaa
    12841 ctccatttcg ggccaagggt cgatgtgctg gatgcctgtc cgaaagcgga agggatgatg
    12901 atgctgatcc ggtcgatgag cccggatgtc attgtcgtgg atgagatcgg ccgcgaagaa
    12961 gatgcggcgg cgattatgga ggcggtaaat gcgggcattt cgctcgtcat gacaacgcac
    13021 ggggaaaact tccgggatat ccaaaaacgc ccgattttaa agaaaatcct cgaatcgtat
    13081 gcgtttgacc gctttctcga actgtcacgg gggagccggc cgggaagggt aacagcggtc
    13141 cgcgatgcgg aagggaacat catccgtacc ggtgaaggtg tttcccgtgc ttaaactttt
    13201 tggagcagca ctgattgtgc tcgccaccag tttcatcggc tttgaggcag caaaacggtt
    13261 aagcgaacgc ccccgccagc tgagaatttt tcaaaacgcg cttcaggcac tagaagtgga
    13321 aatcatgtac gggcataccc cgctgcatga agcggcaaga aaactatcag gccagctccc
    13381 ggatccggct gccgccttct tccgttcctt tgccagccag ttgaccacat tggaaacaac
    13441 ggtcaaagaa gcgtgggaaa aaagccttga cggaatttgg aaactgacgg ccctgaaaga
    13501 aaacgagtat gaagtattgc ggcagctcgg ggaaaacctg ggcaaacatg accgctatac
    13561 cgagcaaaag cagctgctcc tggccctttc acatttagaa agggaagaaa aagaagcgca
    13621 cgaaaggcag ctccgctatg aaaaaatggc aaaaagcctt ggcgtcctca cgggtttact
    13681 gatcgctatt ttactgatct aaagtctcac ggatcatatt gggggaaaag caatgggcat
    13741 tgatgtggac atcattttta aaattgccgg ggtcgggatt gttgtggcgt ttctccacac
    13801 gattctggac caggtcggca aaaaagaata tgcgcaatgg gtcacgcttc tcggttttct
    13861 ttacattttg tttttagtgg catccatcgt aggggatttg ttttccaaaa tcaaaacggt
    13921 ctttcttttt caataagccg ggaaaaaagg ggggatttcc cattgaaatt ttgcaaattg
    13981 cgggtgtggc gctcatcacg actttccttg cgctcatatt aaaagagcag aaaccgaatt
    14041 ttgccttttt gctgacgctt tttgccggct gttttatctt tctttttctg gtggacaaga
    14101 tatacgaaat catccacctg ctgcaaaaaa ttgcccaaaa agggaatgta gacacgatgt
    14161 atatcgaaac gatcctgaaa atcatcggcg tcgcttatat tgccgatttt gcagccaata
    14221 ttacaaaaga tgccgggcag ggggcacttg cggcaaaggt ggagctggcc ggcaaaatca
    14281 ttattttgac aatggccatc cccattctta ccgtgctgat cgaaacgatt gtcaatctcg
    14341 ttccgcgtgc agggagttga ggatatgggg cacaaaaaaa tatacatcgc acttttcatt
    14401 ctgtttgcct tctgtttctt cgcacagtcg gcatccgccg cttcggaaaa tacggacaaa
    14461 caggagaata ttccggaaaa aatggtcgat gaacaattga atcaattgga cttatcagaa
    14521 ctgaaaaact actgggacga cattgtcagc aaatacggcg gatacttgcc ggaaagccag
    14581 aaagggagcc ttatggattt tatgaaaggc gagaagcatt tttccttgca agcctggctg
    14641 aaagggctgc tttcgtatat tttccaggag ctgctgatca acgcaa
//
