LOCUS       gnlProkkaMIIDHJAL_110   4566 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MIIDHJAL_110.
ACCESSION   gnlProkkaMIIDHJAL_110
VERSION     gnlProkkaMIIDHJAL_110
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 09:22:27
            Original ID  :: gnl|Prokka|MIIDHJAL_110
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4566
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4566
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[2469:4566]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2470..4566
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..4566
                     /SMILES="NC(C)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..4566
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(3..338)
                     /locus_tag="ctg110_1"
                     /transl_table=11
                     /translation="MTEEAKLTKTEKLNTVKVTTSNAISKFGDVLFDYVNTVFLSSIPN
                     GGFWLSFYQSSEVLISVFFNFWGGAVSDSGNRKRIIFHCDLISGFICLILAIFIPKSFF
                     IYTIILIN"
     CDS             519..1151
                     /locus_tag="ctg110_2"
                     /transl_table=11
                     /translation="MAYRIQVDGISNSGKTTLCNNLSKQLGYKIVPESIRYLENRLNEK
                     GDNILYVPKNIQEELRNQEILFDLEFDKWFDANYFADHGQNVVIDKSPYSIVATAFAFE
                     SSNISGTYNKSLEFLDDFIEKAKRYKLYSPDLLLLLKADSSASSKRNLERNHHLLSVWT
                     QESTRQKQEEILEKEFQELDMKKALIDTSNLSPRDVYDEALKQITSL"
     CDS             1187..2461
                     /locus_tag="ctg110_3"
                     /transl_table=11
                     /translation="MITIAELIMFLMLLQCLWHIARTMLVNKKIKQNKNNAASFKETRD
                     EKPKFFIVIPCLQEQKIINRTIDDFVNIITSTKIDAKLFIVTTDKEKLLTNQGKTTFDI
                     VKEKIDTSDSYKDIKLLNYPGVNGMMADQLNYAFDTIYKMYDIDEKSSYFCVYNADSRP
                     GKDAFLQAKTVALKKHFPLIMQEYSAFFSNLNTLSPIMQGFAVYQTNFELINGLTNAIL
                     PSIFLRNHVVGHGLFVRFDYLKRIGSFNTEFWCEDIYLSFYLRSQGIIIEPLFALEYGE
                     SPKNIQILAKQNANWFKTLSDNKKFYQILSKNKDTKQLNTFLYYLNQVRGAFAWLLLPS
                     FYLVIFIFLIFINSGLALVFTLVYLTTTFLRFWLSNSIAKNLHGKLPVNNFLLAFESSI
                     AYLISNVGPLYLVFHRKGTKYKTER"
     CDS             2470..4566
                     /NRPS_PKS="Domain: AMP-binding (8-390). E-value: 5.9e-69.
                     Score: 224.4. Matches aSDomain:
                     nrpspksdomains_ctg110_4_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (501-540). E-value: 7.6e-08.
                     Score: 24.7. Matches aSDomain:
                     nrpspksdomains_ctg110_4_PP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     185.9; E-value: 1.6e-56)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_4"
                     /sec_met_domain="AMP-binding (E-value: 3.2e-69, bitscore:
                     221.5, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 5.4e-09, bitscore:
                     24.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFIIDNFIQRSQNTPDQVAVKSPNGDYTYQEISNIAQQLAAKLDE
                     ENAQDIVPFYLKDTRFVLPTVIGIWLSNRIPMPLVSALDLPEATDRVKEVQWDTLITDL
                     PATLKQKNIIQVDLFNQNNHADFKAKPFSQKNVYILSTSGSTGIPKKVFLTESNLKWIL
                     TRLYSLINVNETTKFLFSTPYSFDVSLTELLSPVIAGAELVCLPTSPSNSESIRLIPKL
                     INQKQITHLSLSPSFAEALLDIVGPEAFDKLKFLMVAGEAFPINLAKKLKRALNKGCKV
                     FNLYGPTETTVYSTYHQVTENEEEYVPIGRPLPEGKVKVLDANNNEAKKGELYIGGNGV
                     TDGYLLDSVKSSSSFITLDGERYYKTGDKVEILQNGELLFLEREDDQVQVNGIRVELGE
                     IQTLVSKIADVTTAIAKFKNKRIYIFYISSQDKEAEIKSKLPTYLNPIIIKVDHFLYTY
                     NRKIDTQRMIDEYYNRSLTTDSSNTLDELKKLIAKYHVNEIKELDSLDSVRFIVDVENT
                     FKIQIDDAQFSLLNTLERLAAYIDKQQTNTAAETREQANEADLLNLKLLFANFSSSYED
                     AKITASSTQQSLFSQQKPSFDLLRVSFPTINFEEIQKIRQIFTDLTTKIDLLKFAWFKD
                     RDGKLYFKKIINPAPISLVTANSFSETDLEKVMYSKPGSPIHCLIFNMKKQELNIVFSH
                     HALDA"
     aSDomain        2494..3639
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg110_4_AMP-binding.1"
                     /evalue="5.90E-69"
                     /label="ctg110_4_AMP-binding.1"
                     /locus_tag="ctg110_4"
                     /protein_end="390"
                     /protein_start="8"
                     /score="224.4"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="QRSQNTPDQVAVKSPNGDYTYQEISNIAQQLAAKLDEENAQDIVP
                     FYLKDTRFVLPTVIGIWLSNRIPMPLVSALDLPEATDRVKEVQWDTLITDLPATLKQKN
                     IIQVDLFNQNNHADFKAKPFSQKNVYILSTSGSTGIPKKVFLTESNLKWILTRLYSLIN
                     VNETTKFLFSTPYSFDVSLTELLSPVIAGAELVCLPTSPSNSESIRLIPKLINQKQITH
                     LSLSPSFAEALLDIVGPEAFDKLKFLMVAGEAFPINLAKKLKRALNKGCKVFNLYGPTE
                     TTVYSTYHQVTENEEEYVPIGRPLPEGKVKVLDANNNEAKKGELYIGGNGVTDGYLLDS
                     VKSSSSFITLDGERYYKTGDKVEILQNGELLFLEREDDQVQV"
     aSModule        2494..4089
                     /complete
                     /domains="nrpspksdomains_ctg110_4_AMP-binding.1"
                     /domains="nrpspksdomains_ctg110_4_PP-binding.1"
                     /locus_tags="ctg110_4"
                     /monomer_pairings="Ala -> Ala"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       2881..2934
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg110_4_0001"
                     /evalue="2.60E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg110_4"
                     /protein_end="155"
                     /protein_start="137"
                     /score="13.9"
                     /tool="antismash"
                     /translation="YILSTSGSTGIPKKVFLT"
     CDS_motif       3460..3534
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg110_4_0002"
                     /evalue="1.90E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg110_4"
                     /protein_end="355"
                     /protein_start="330"
                     /score="20.2"
                     /tool="antismash"
                     /translation="GELYIGGNGVTDGYLLDSVKSSSSF"
     CDS_motif       3607..3672
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg110_4_0003"
                     /evalue="4.00E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg110_4"
                     /protein_end="401"
                     /protein_start="379"
                     /score="25.6"
                     /tool="antismash"
                     /translation="FLEREDDQVQVNGIRVELGEIQ"
     aSDomain        3973..4089
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg110_4_PP-binding.1"
                     /evalue="7.60E-08"
                     /label="ctg110_4_PP-binding.1"
                     /locus_tag="ctg110_4"
                     /protein_end="540"
                     /protein_start="501"
                     /score="24.7"
                     /tool="antismash"
                     /translation="LDSLDSVRFIVDVENTFKIQIDDAQFSLLNTLERLAAYI"
ORIGIN
        1 atattgataa gtataatcgt ataaataaaa aatgacttag gaataaaaat tgctaatata
       61 agacaaataa atccactaat caaatcacaa tgaaaaataa ttcgctttct attaccactg
      121 tcagagacag cacctcccca aaaattaaaa aatacgctga ttaaaacttc actactttgg
      181 tagaaagaca gccaaaaacc tccatttgga atagaagaaa gaaatactgt atttacgtag
      241 tcaaataaaa catcaccaaa tttcgaaatc gcattactgg tagtaacctt aaccgtattt
      301 agcttttccg tttttgttaa ttttgcttct tctgtcattg aatcaccttc ataaaaagta
      361 ttgactttga aatnnnnnnn nnnnnnnnnn nnnnaaaata aatgattgtt aataaattat
      421 agcactatta aaaaagcttt aacaaaaaag ttatgcatct tgtttcttaa gaaaggaaga
      481 tattaatatt atgagtagag gaaaaataat acttatagat ggcatatcga attcaggtag
      541 atggcatatc gaattcaggt aaaactactt tatgtaataa cctatcaaaa caactaggtt
      601 ataaaattgt tcctgaatca ataagatatc tagaaaatag gttaaatgaa aaaggagata
      661 atattttata tgttcctaaa aatattcaag aagaattacg gaatcaggaa atattatttg
      721 acctagaatt tgataaatgg tttgatgcaa attattttgc tgatcatgga caaaatgttg
      781 taattgataa atcaccctat tcaatcgttg cgacagcatt tgctttcgaa tcttctaata
      841 tatctggaac atataataaa tcgttagagt ttttagacga ttttatagaa aaagctaaac
      901 gatataaatt atacagtccg gacttgctat tactattaaa agctgatagt tctgcttcat
      961 caaagagaaa tttggaacgg aatcatcacc ttttaagtgt ctggactcaa gaaagtacaa
     1021 gacaaaagca agaagaaata ttagaaaaag aatttcaaga attagacatg aaaaaggcac
     1081 taattgatac atcaaatctt tcaccacggg atgtctatga tgaggcttta aaacaaatca
     1141 ctagtttgtg atttaactca tcaaatttta ttaaggaggg ctaattatga taacaatagc
     1201 agaattaata atgtttctaa tgctactaca atgtttgtgg cacatagcta gaacaatgct
     1261 agtgaataaa aaaataaagc aaaataaaaa taatgctgcg agctttaaag aaactagaga
     1321 tgaaaaacca aaattcttta tagttattcc atgtttacaa gaacaaaaga taattaatag
     1381 aacgatagat gattttgtaa atattattac tagtacaaaa attgatgcaa aattattcat
     1441 cgtaactact gataaagaaa aattgctaac caatcaagga aaaactacat ttgacattgt
     1501 aaaagaaaag attgatacat cagatagtta taaagacatt aaacttttaa actatcctgg
     1561 agtaaatggc atgatggctg atcaattaaa ttatgcattc gatacaattt ataaaatgta
     1621 tgatattgat gagaaaagct cctatttctg tgtctataat gccgatagtc gccccggaaa
     1681 agacgcattc cttcaggcaa aaacagttgc cctaaagaag cattttcctt taattatgca
     1741 agaatattct gcatttttct ctaacttaaa tacgttaagt ccaattatgc aaggcttcgc
     1801 tgtttatcaa actaattttg aattaataaa tggactaaca aatgctatat taccttctat
     1861 tttcttaagg aatcatgttg taggccatgg actttttgtc agatttgatt atttaaaacg
     1921 aataggtagc tttaatactg aattttggtg tgaagatatt tatcttagtt tctatttgag
     1981 aagtcaggga attataattg aaccattatt tgccttggaa tatggggaat ctcctaaaaa
     2041 tattcaaata cttgctaaac aaaatgctaa ttggttcaaa acattgtctg ataataaaaa
     2101 attttatcaa atattaagta agaataaaga tactaaacaa ttgaatactt ttctttatta
     2161 tctaaatcaa gtaagaggag cctttgcatg gctattacta cctagctttt atctagttat
     2221 ctttatattt cttattttta taaatagtgg attagcacta gtttttactt tagtttatct
     2281 aactaccaca tttcttcgat tctggttatc taattcaatc gcgaaaaatt tacacggaaa
     2341 attaccggta aataatttcc ttctagcgtt tgaaagtagc atagcatatt taatttctaa
     2401 tgtaggtcct ctctatctag tatttcatag aaaaggaact aaatataaaa cagaaaggtg
     2461 agtttcagta tgtttattat tgataatttt attcaacgca gccagaatac tcctgatcaa
     2521 gtggcagtta aatcaccaaa tggtgattat acctatcaag aaatttccaa tattgcccag
     2581 caattagccg ctaaacttga tgaggaaaat gctcaggaca tcgttccctt ttatttaaaa
     2641 gatacccgtt ttgtactgcc cacagtaatt ggaatttggc tatccaaccg catccctatg
     2701 ccacttgtat cagcgttaga cctacctgaa gccactgatc gtgtaaaaga agttcaatgg
     2761 gatactttaa taactgactt acctgccaca cttaagcaga aaaatatcat tcaagttgat
     2821 cttttcaatc agaataatca cgccgacttt aaagctaaac cgttctcgca aaaaaatgta
     2881 tacatcctct ctacttctgg cagtaccggc attcctaaaa aagtttttct gacagaaagc
     2941 aatctaaagt ggatccttac aagactgtac tcattaatta acgtcaacga gacgaccaaa
     3001 tttttatttt caacgcctta ttcttttgat gtttcattaa cagagcttct gtcgcccgtt
     3061 attgccggtg ccgagctggt ttgtctccca acaagtcctt ctaattcaga gagtatcagg
     3121 ctaattccca aattaattaa tcaaaagcaa ataacgcacc tttccttatc cccttcattt
     3181 gcggaggcac ttcttgatat cgttggtcct gaagcctttg ataaactcaa gtttctgatg
     3241 gtagccggtg aagcatttcc gattaatttg gcaaaaaaat tgaaacgggc gcttaataag
     3301 ggatgcaaag tttttaatct ttatggtccg actgaaacaa ctgtctattc tacttatcat
     3361 caggtaactg aaaatgaaga agaatacgta ccgattggcc gcccattacc agagggaaag
     3421 gtaaaagtcc ttgatgcaaa caataatgaa gcaaaaaaag gtgaattata tattggcgga
     3481 aatggagtaa cagacggcta tcttttagat tctgttaaaa gcagctcaag cttcatcact
     3541 cttgacggtg aacgctatta taaaactggt gataaggtag aaattttaca aaacggtgag
     3601 ctacttttcc tagaaagaga agacgatcaa gtccaagtta acggaatccg tgtggaatta
     3661 ggtgaaattc aaactctagt atcgaaaatc gctgatgtta ccacagcaat tgcgaagttc
     3721 aaaaacaagc gaatctatat tttttacatt agttcgcaag ataaagaagc tgagattaaa
     3781 agtaaactgc caacttatct caatccaata attattaagg tcgatcactt cttgtacacc
     3841 tacaaccgta agattgatac gcaaagaatg atcgacgagt attataatcg ttctttgact
     3901 actgatagct ctaacacttt agacgaattg aaaaagttga tagccaaata ccacgttaat
     3961 gaaattaaag agctggattc tctggattca gtgcgcttca ttgttgatgt agaaaatact
     4021 tttaagattc agattgatga tgcccagttc tcactgttga acacgcttga gcgcttggca
     4081 gcatatattg acaagcagca aacaaataca gctgcagaga ctcgcgagca agcaaatgaa
     4141 gctgacttac ttaatcttaa attgctgttt gcaaactttt cgagcagcta tgaggatgcg
     4201 aaaattactg cttcatcaac gcagcagagt ctcttttcac aacaaaaacc atcttttgac
     4261 ctgctaagag tatcttttcc gacaattaac tttgaagaaa ttcagaagat tagacagatt
     4321 tttactgatt taactactaa gatagatcta ttgaaatttg cttggtttaa agatcgagac
     4381 ggtaaactat atttcaagaa gataatcaat ccagctccaa tctcacttgt taccgcaaac
     4441 agcttttccg aaactgactt agaaaaagtg atgtattcta agcctggttc gccaattcat
     4501 tgccttattt tcaatatgaa gaagcaggag ttaaacattg tcttttcaca ccacgctcta
     4561 gatgcc
//
